A physiological saline injection device for hemodynamic monitoring and a working method thereof

Abstract

The invention provides a physiological saline push injection device for hemodynamic monitoring and a working method, which relates to the field of liquid push injection devices, and comprises a delivery pipe and a push injection pump connected in series to the delivery pipe, wherein a refrigeration mechanism acting on the delivery pipe is arranged between the inlet end of the delivery pipe and the push injection pump, a first temperature sensor is arranged at the inlet of the push injection pump, and a second temperature sensor is arranged at the outlet end of the delivery pipe, the first temperature sensor and the second temperature sensor obtain temperature data of a medium in the delivery pipe and send the data to a controller, and the controller is used to control the refrigeration power of the refrigeration mechanism and the pumping flow rate of the push injection pump; in view of the problem that it is difficult to accurately control the temperature and flow rate during the current low-temperature saline push injection process, physiological saline is transported through the delivery pipe and a refrigeration mechanism is arranged to cool the physiological saline, the physiological saline is transported stably and unidirectionally by the push injection pump, uniform injection speed is ensured and contamination is avoided, the cooling temperature of the physiological saline is controlled in combination with temperature sensors at multiple points, the power of the refrigeration mechanism is adjusted in time according to environmental changes, the output temperature of the physiological saline is ensured to be accurate, and the operation burden of medical staff is reduced.

Description

Technical Field

[0001] The invention relates to the field of liquid push injection devices, and in particular to a physiological saline push injection device for hemodynamic monitoring and a working method. Background Art

[0002] Pulse indicator continuous cardiac output (Picco) is a common hemodynamic monitoring tool in clinical practice. Because it is relatively minimally invasive (only an arterial catheter and a central venous catheter are required) and can provide a wealth of hemodynamic indicators, it is widely used in patients with hemodynamic instability in critical care medicine and has important guiding value for the clinical treatment of patients.

[0003] Since Picco is based on thermodilution technology, low-temperature saline at 2 to 15°C is usually injected at a uniform speed from the venous end. After the injected cold saline flows through the right heart, pulmonary circulation, and left heart, its temperature change is sensed by the temperature receptor located in the femoral artery, and the relevant hemodynamic indicators are calculated. This requires clinicians to prepare frozen saline in advance, and after thawing, draw an appropriate amount of low-temperature saline (usually 15-20 ml) with a sterile syringe and inject it into the venous catheter end of Picco at a uniform speed and within a specified time (usually 5 seconds). In this process, the preparation of ice saline is cumbersome, and the temperature cannot be accurately controlled; the injection process also requires strict sterility, and it needs to be injected at a uniform speed at fixed time intervals. These mechanical and repetitive tasks increase the clinical workload.

[0004] At present, routine Picco operations require the preparation of ice saline in advance, thawing, and manual injection after extraction with a syringe. There are the following problems in this process: 1. The temperature of the ice saline after thawing is difficult to control accurately, and low-temperature saline of different temperatures may cause bias in the Picco results; 2. When injecting, a certain amount of low-temperature saline must be extracted with a sterile syringe, and then the syringe is placed on the Picco central venous catheter connection before injection. This operation must be performed at least 3 times. Repeated extraction and injection of low-temperature saline may contaminate the syringe, thereby posing a risk of bloodstream infection in patients; 3. It is difficult to ensure a uniform speed for manual injection, and at different injection speeds, the time for heat exchange between the low-temperature saline and the environment is different, which will cause the temperature of the low-temperature saline when injected into the human body to deviate, and will also affect the accuracy of the measurement results; 4. For critically ill patients, several Picco measurements may be required a day. The above cumbersome and mechanical operations increase the burden on clinicians and the risk of infection for patients. Summary of the invention

[0005] The purpose of the present invention is to address the defects of the prior art and provide a physiological saline push injection device and working method for hemodynamic monitoring. The physiological saline is delivered through a delivery tube and a refrigeration mechanism is set to cool the physiological saline. The physiological saline is stably delivered in one direction by an injection pump to ensure uniform injection and avoid contamination. The cooling temperature of the physiological saline is controlled by combining multi-point temperature sensors. The power of the refrigeration mechanism is adjusted in time according to environmental changes to ensure that the output temperature of the physiological saline is accurate and reduce the operating burden of medical staff.

[0006] The first object of the present invention is to provide a physiological saline push injection device for hemodynamic monitoring, which adopts the following scheme:

[0007] It includes a delivery pipe and an injection pump connected in series to the delivery pipe. A refrigeration mechanism acting on the delivery pipe is provided between the inlet end of the delivery pipe and the injection pump. A first temperature sensor is provided at the inlet of the injection pump, and a second temperature sensor is provided at the outlet end of the delivery pipe. The first temperature sensor and the second temperature sensor obtain temperature data of the medium in the delivery pipe and send it to a controller. The controller is used to control the refrigeration power of the refrigeration mechanism and the pumping flow rate of the injection pump.

[0008] Furthermore, a three-way joint is connected in series between the outlet end and the injection pump, and the three-way joint is connected to the exhaust pipe.

[0009] Furthermore, it also includes an incubator for accommodating the delivery tube, the injection pump and the first sensor, and the inlet end and the outlet end of the delivery tube are both located outside the incubator.

[0010] Furthermore, the refrigeration mechanism and the injection pump are fixed in the insulated box, and the second sensor is located at the outlet end of the delivery pipe outside the insulated box.

[0011] Furthermore, the heat preservation box is provided with a heating mechanism to increase the temperature inside the heat preservation box and the temperature of the medium at the outlet end.

[0012] Furthermore, the delivery pipe between the inlet end and the push pump is coiled to form a multi-section curved structure, and the working area of ​​the refrigeration mechanism wraps the multi-section curved structure.

[0013] Furthermore, the inlet end is provided with a first connector to connect to a physiological saline storage bag; and the outlet end is provided with a second connector to connect to a syringe.

[0014] Furthermore, the push pump is a flow pump, and a flow meter is provided at the outlet end of the delivery pipe. The flow meter obtains flow data of the medium in the delivery pipe at the outlet end and sends it to the controller.

[0015] Furthermore, the refrigeration mechanism is wrapped around the outer ring of the delivery pipe along the axial direction of the delivery pipe, and performs heat exchange with the medium inside the delivery pipe.

[0016] A second object of the present invention is to provide a method for operating the physiological saline push injection device for hemodynamic monitoring as described above, comprising the following steps:

[0017] The inlet end of the delivery tube obtains and delivers the physiological saline solution, and the cooling mechanism cools the physiological saline solution in the delivery tube;

[0018] The push pump drives the physiological saline to flow along the delivery tube and pushes the cooled physiological saline to the outlet end, and the first temperature sensor and the second temperature sensor measure the temperature of the physiological saline at the corresponding position;

[0019] The controller adjusts the power of the refrigeration mechanism according to the first temperature sensor data, and adjusts the power of the refrigeration mechanism and / or the pumping flow of the injection pump according to the second temperature sensor data, so that the outlet end outputs physiological saline that meets the temperature requirement.

[0020] Compared with the prior art, the present invention has the following advantages and positive effects:

[0021] (1) In view of the difficulty in accurately controlling the temperature and flow rate during the current low-temperature saline push injection process, physiological saline is delivered through a delivery tube and a refrigeration mechanism is set up to cool the physiological saline. The physiological saline is delivered stably in one direction through an injection pump to ensure uniform injection speed and avoid contamination. The cooling temperature of the physiological saline is controlled by combining multiple temperature sensors. The power of the refrigeration mechanism is adjusted in time according to environmental changes to ensure the accuracy of the output temperature of the physiological saline and reduce the operating burden of medical staff.

[0022] (2) The temperature of the saline solution at the outlet is measured by a temperature sensor and adjusted by a controller, which significantly reduces the workload of medical staff in Picco monitoring. The temperature sensor feedback controls the injection pump and refrigeration mechanism to achieve precise temperature control. The injection pump is used to achieve uniform injection speed, reducing the deviation of Picco results caused by manual injection. Instant cooling and a relatively closed one-way flow delivery tube reduce the chance of bloodstream infection in patients.

[0023] (3) The delivery tube is provided with an inlet end and an outlet end and a connector to facilitate connection with an external saline supply source and a syringe. The connector at the inlet end can be connected to a storage container such as a saline bag / bottle, and normal temperature saline can be directly obtained from the sterile storage container and cooled. The normal temperature saline is supplied and cooled in real time according to demand, thereby reducing the temperature fluctuation of the pre-cooled saline.

[0024] (4) The temperature at the outlet is monitored. Compared with the temperature monitoring before or after the injection pump, the temperature of the saline solution at the output position is directly obtained, thereby reducing the temperature fluctuation caused by the heat exchange between the saline solution and the environment during the flow of the saline solution in the delivery tube. The final output temperature is used as a reference to adjust the refrigeration mechanism and the injection pump to obtain and output the saline solution at the required temperature.

[0025] (5) Considering the change in the flow rate of the saline solution in the delivery tube caused by the change in the flow rate of the injection pump, the heat exchange time between the low-temperature saline and the environment at different injection speeds affects the temperature of the low-temperature saline when it is finally output. The temperature measured by the second temperature sensor is compared with the required temperature. On the one hand, under the premise of meeting the injection flow rate range, the injection pump flow rate is adjusted to adjust the heat exchange time to achieve fine-tuning of the output temperature and finally reach the required temperature; on the other hand, the power of the refrigeration mechanism is adjusted to ensure that the temperature of the saline supplied to the injection pump meets the requirements of Picco operation.

[0026] (6) During operation, unstable operation of the refrigeration mechanism will affect the temperature of the saline solution in the delivery pipe. In order to prevent the low-temperature saline solution output through the outlet from being too cold, a heating mechanism is provided to compensate for the temperature of the saline solution in the delivery pipe and to timely heat up the overcooled low-temperature saline solution to ensure that the temperature of the output saline solution can meet the demand. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The accompanying drawings in the specification, which constitute a part of the present invention, are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute improper limitations on the present invention.

[0028] Figure 1 Schematic diagram of the structure of the physiological saline push injection device for hemodynamic monitoring in Example 1 or 2 of the present invention.

[0029] Among them, 1. delivery pipe, 2. injection pump, 3. refrigeration mechanism, 4. first temperature sensor, 5. second temperature sensor, 6. three-way joint, 7. exhaust pipe, 8. insulation box, 9. inlet end, 10. outlet end, 11. flow meter. DETAILED DESCRIPTION

[0030] Example 1

[0031] In a typical embodiment of the present invention, Figure 1 As shown, a physiological saline push injection device for hemodynamic monitoring is provided.

[0032] like Figure 1The physiological saline push injection device for hemodynamic monitoring shown can obtain physiological saline from an external physiological saline supply source and output it uniformly and at a constant temperature after cooling it down, especially for supplying low-temperature saline during Picco determination. The physiological saline is delivered through the delivery tube 1 and a refrigeration mechanism 3 is set to cool the physiological saline. The physiological saline is delivered stably in one direction through the push injection pump 2 to ensure uniform injection and avoid contamination. The cooling temperature of the physiological saline is controlled by combining multiple temperature sensors. The power of the refrigeration mechanism 3 is adjusted in time according to environmental changes to ensure the accuracy of the output physiological saline temperature and reduce the operating burden of medical staff.

[0033] Specific, combined Figure 1 The physiological saline push injection device for hemodynamic monitoring shown in the figure mainly includes a delivery tube 1, an injection pump 2, a refrigeration mechanism 3 and a temperature sensor, wherein one end of the delivery tube 1 is an inlet end 9, which can obtain external physiological saline, and the other end is an outlet end 10, which can output the physiological saline; when the physiological saline flows along the delivery tube 1, it is cooled by the refrigeration mechanism 3 so that its temperature can reach the required requirement, and it is pressurized by the injection pump 2 so that it can stably output to meet the stable flow requirement during the measurement process, and the temperature of the physiological saline medium transported in the delivery tube 1 is measured by the temperature sensor, and the working state of the refrigeration mechanism 3 and the injection pump 2 is adjusted by the controller according to the measured temperature to form feedback control.

[0034] Since this embodiment is used for Picco hemodynamics low-temperature saline injection, the amount, temperature, and injection speed of the low-temperature saline during the injection process have high requirements, especially the temperature, which directly determines the accuracy of Picco measurement. Compared with the current method of thawing and extracting frozen saline before injection, when thawing saline or using pre-cooled saline, there is a problem that the temperature of the cooled saline in the delivery pipe 1 fluctuates, resulting in the problem that the temperature of the saline that finally enters the patient's body does not meet the standard. In this embodiment, physiological saline is extracted from a physiological saline supply source and cooled in real time, so that the saline is cooled in the delivery pipe 1. A temperature sensor is provided at the end of the pipe, which can accurately ensure the output saline temperature.

[0035] In addition, the inlet end 9 of the delivery tube 1 in this embodiment is provided with a first connector, which can be connected to a storage container such as a saline storage bag. There is no need for pre-cooling, but only the existing finished saline bags, saline bottles, etc. need to be used. It is easy to use and can reduce the risk of contamination of saline during pre-treatment processes such as pre-cooling and thawing, reduce the operation of medical staff and improve efficiency.

[0036] The temperature sensor is a component for obtaining temperature data, which facilitates temperature data collection. Other methods or components can also be used to obtain temperature. In this embodiment, the temperature sensors are dispersedly arranged, a first temperature sensor 4 is provided at the inlet of the push pump 2, and a second temperature sensor 5 is provided at the outlet end 10 of the delivery pipe 1. The first temperature sensor 4 and the second temperature sensor 5 obtain the temperature data of the medium in the delivery pipe 1 and send it to the controller. The controller is used to control the refrigeration power of the refrigeration mechanism 3 and the pumping flow of the push pump 2.

[0037] In this embodiment, the temperature sensors are dispersedly arranged to realize multi-point temperature monitoring. The temperature of the physiological saline at the outlet end 10 is measured by the temperature sensor, and feedback adjustment is performed through the controller, which significantly reduces the workload of medical personnel in Picco monitoring. The push pump 2 and the refrigeration mechanism 3 are controlled by the temperature sensor feedback to achieve precise temperature control. The push pump is used to achieve uniform injection speed, reducing the Picco result deviation caused by manual injection. The instant cooling and the relatively closed one-way flow delivery tube 1 reduce the chance of bloodstream infection in patients.

[0038] It should be particularly pointed out that, compared with monitoring the temperature before or after the push pump 2, monitoring the temperature of the outlet end 10 directly obtains the temperature of the saline solution at the output position, reduces the temperature fluctuation caused by heat exchange between the saline solution and the environment during the flow of the saline solution in the delivery tube 1, and uses the final output temperature as a reference to adjust the refrigeration mechanism 3 and the push pump 2 to obtain and output the saline solution at the required temperature.

[0039] Furthermore, the push pump 2 is selected as a flow pump, which can control the pumping flow rate. The outlet end 10 of the delivery pipe 1 is provided with a flow meter 11, which obtains the flow data of the medium in the delivery pipe 1 at the outlet end 10 and sends it to the controller.

[0040] Considering the change in flow rate of the saline solution in the delivery tube 1 caused by the change in flow rate of the push pump 2, the heat exchange time between the low-temperature saline and the environment at different injection speeds affects the temperature of the low-temperature saline when it is finally output. In view of the error problem existing in manual push injection mentioned in the background technology, the position of the temperature sensor is specially configured in this embodiment to ensure precise control of the output temperature of the saline solution.

[0041] The temperature measured by the second temperature sensor 5 is compared with the required temperature. On the one hand, under the premise of meeting the injection flow range, the flow of the injection pump 2 is adjusted to adjust the heat exchange time to achieve fine-tuning of the output temperature and finally reach the required temperature; on the other hand, the power of the refrigeration mechanism 3 is adjusted to ensure that the temperature of the physiological saline supplied to the injection pump 2 meets the requirements of Picco operation.

[0042] The control is performed respectively from the main body of the push pump 2 and the refrigeration mechanism 3 upstream of the push pump 2, so as to comprehensively consider the temperature of the physiological saline itself and environmental factors, and reasonably ensure that the temperature of the physiological saline is constant when it is output from the outlet end 10.

[0043] It can be understood that the constant temperature mentioned in this embodiment means that the temperature of the physiological saline output from the outlet 10 is stable within a certain range. For example, the temperature of the physiological saline output from the outlet 10 may fluctuate within the range of 4.5°C-5.5°C, taking the low-temperature saline required to be 5°C as an example. The corresponding physiological saline temperature range is selected according to the accuracy requirements of the Picco measurement.

[0044] In order to ensure the flow rate of the output of the saline solution from the outlet end 10 is stable, a three-way joint 6 is connected in series between the outlet end 10 and the injection pump 2, and the three-way joint 6 is connected to the exhaust pipe 7 to discharge the bubbles in the delivery pipe 1. The delivery pipe 1 is provided with an inlet end 9 and an outlet end 10 and a joint, which is convenient for docking with an external saline supply source and a syringe. The joint of the inlet end 9 can be connected to a storage container such as a saline bag / bottle, and normal temperature saline solution is directly obtained from the sterile storage container and cooled, and supplied and cooled in real time according to demand, thereby reducing the temperature fluctuation of the pre-cooled saline solution.

[0045] For the needs of cooling, regulating and maintaining the saline solution in the delivery tube 1, for temperature maintenance, an incubator 8 is also included to accommodate the delivery tube 1, the push pump 2 and the first sensor, and the inlet end 9 and the outlet end 10 of the delivery tube 1 are both located outside the incubator 8. The refrigeration mechanism 3 and the push pump 2 are fixed in the incubator 8, and the second sensor is located at the outlet end 10 of the delivery tube 1 outside the incubator 8.

[0046] The inlet end 9 is provided with a first connector for connecting to a physiological saline storage bag; the outlet end 10 is provided with a second connector for connecting to a syringe.

[0047] At the same time, for cooling, the refrigeration mechanism 3 is wrapped around the outer circle of the delivery pipe 1 along the axial direction of the delivery pipe 1, and exchanges heat with the medium inside the delivery pipe 1; the delivery pipe 1 between the inlet end 9 and the push pump is coiled to form a multi-section curved structure, and the working area of ​​the refrigeration mechanism 3 wraps the multi-section curved structure.

[0048] The refrigeration mechanism 3 in this embodiment can be an existing refrigeration component, such as a semiconductor refrigeration component.

[0049] Temperature regulation includes not only the cooling process of the saline in the delivery tube 1 , but also the heating process of the supercooled saline. The insulated box 8 is provided with a heating mechanism to increase the temperature in the insulated box 8 and the medium temperature at the outlet end 10 .

[0050] It is understandable that during operation, unstable operation of the refrigeration mechanism 3 will affect the temperature of the saline solution in the delivery tube 1. In order to prevent the low-temperature saline solution output through the outlet port 10 from being too cold, a heating mechanism is provided to compensate for the temperature of the saline solution in the delivery tube 1 and to timely heat up the overcooled low-temperature saline solution to ensure that the temperature of the output saline solution can meet the demand.

[0051] At the same time, it should be particularly pointed out that the heating mechanism can be selected from existing heating equipment, such as electric heating wires, etc., and the output power of the heating mechanism can be adjusted to increase or decrease the internal temperature of the insulation box 8.

[0052] By increasing the internal temperature of the incubator 8 and performing high-temperature disinfection on the inside of the incubator 8, the entire push injection device can be kept in a sterile state, thereby reducing the risk of infection.

[0053] Example 2

[0054] In another typical embodiment of the present invention, Figure 1 As shown, a working method of a physiological saline push injection device for hemodynamic monitoring is given.

[0055] Based on the physiological saline injection device for hemodynamic monitoring in Example 1, the working method includes the following steps:

[0056] The inlet end 9 of the delivery tube 1 obtains and delivers the saline solution, and the cooling mechanism cools the saline solution in the delivery tube 1;

[0057] The injection pump 2 drives the physiological saline to flow along the delivery tube 1 and injects the cooled physiological saline to the outlet end 10, and the first temperature sensor 4 and the second temperature sensor 5 measure the temperature of the physiological saline at the corresponding position;

[0058] The controller adjusts the power of the refrigeration mechanism 3 according to the data of the first temperature sensor 4, and adjusts the power of the refrigeration mechanism 3 and / or the pumping flow of the injection pump 2 according to the data of the second temperature sensor 5, so that the outlet end 10 outputs physiological saline that meets the temperature requirements.

[0059] On the one hand, the temperature of the outlet end 10 is monitored, and compared with the temperature monitoring before or after the push pump 2, the temperature of the physiological saline at the output position is directly obtained, so as to reduce the temperature fluctuation caused by the heat exchange between the physiological saline and the environment during the flow of the physiological saline in the delivery tube 1. The final output temperature is used as a reference to adjust the refrigeration mechanism 3 and the push pump 2, and the physiological saline of the required temperature is obtained and output.

[0060] On the other hand, considering the change in flow rate of the physiological saline in the delivery tube 1 caused by the change in the flow rate of the injection pump 2, the heat exchange time between the low-temperature saline and the environment at different injection speeds affects the temperature of the low-temperature saline when it is finally output. Under the premise of meeting the injection flow rate range, the flow rate of the injection pump 2 is adjusted to adjust the heat exchange time to achieve fine-tuning of the output temperature.

[0061] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A physiological saline injection device for hemodynamic monitoring, characterized in that: It includes a delivery pipe and a push pump connected in series to the delivery pipe, a refrigeration mechanism acting on the delivery pipe is provided between the inlet end of the delivery pipe and the push pump, a first temperature sensor is provided at the inlet of the push pump, and a second temperature sensor is provided at the outlet end of the delivery pipe, the first temperature sensor and the second temperature sensor obtain temperature data of the medium in the delivery pipe and send it to a controller, and the controller is used to control the refrigeration power of the refrigeration mechanism and the pumping flow rate of the push pump; The inlet end is provided with a first connector to connect to a physiological saline storage bag, obtain normal temperature physiological saline from a sterile storage container and cool it, and supply and cool it in real time according to demand; The temperature of the physiological saline solution at the output position is directly obtained by using the first temperature sensor and the second temperature sensor, and the push pump and the refrigeration mechanism are controlled by the temperature sensor feedback to achieve precise temperature control, that is, the power of the refrigeration mechanism is adjusted according to the data of the first temperature sensor, and the power of the refrigeration mechanism and / or the pumping flow of the push pump are adjusted according to the data of the second temperature sensor, so that the outlet end outputs the physiological saline solution that meets the temperature requirements and the Picco operation requirements; The physiological saline storage bag storage container is connected, and no pre-cooling is required. Instead, only the existing finished physiological saline bags and physiological saline bottles can be used, which is convenient for use and can reduce the risk of contamination of the saline during pre-cooling and thawing pretreatment; The delivery pipe between the inlet end and the injection pump is coiled to form a multi-section curved structure, and the working area of ​​the refrigeration mechanism wraps the multi-section curved structure; The refrigeration mechanism is wrapped around the outer ring of the delivery pipe along the axial direction of the delivery pipe and performs heat exchange with the medium inside the delivery pipe; Also included is an incubator housing the delivery tube, the injection pump, and the first sensor, wherein the inlet end and the outlet end of the delivery tube are both located outside the incubator; The incubator is provided with a heating mechanism to increase the temperature inside the incubator and the temperature of the medium at the outlet. Specifically, the heating mechanism is used to perform temperature compensation on the saline in the delivery tube to prevent the low-temperature saline output through the outlet from being too cold.

2. The physiological saline injection device for hemodynamic monitoring according to claim 1, characterized in that: A three-way joint is connected in series between the outlet end and the injection pump, and the three-way joint is connected to the exhaust pipe.

3. The physiological saline injection device for hemodynamic monitoring according to claim 1, characterized in that: The refrigeration mechanism and the injection pump are fixed in the heat preservation box, and the second sensor is located at the outlet end of the delivery pipe outside the heat preservation box.

4. The physiological saline injection device for hemodynamic monitoring according to claim 1, characterized in that: The outlet end is provided with a second connector for connecting with a syringe.

5. The physiological saline injection device for hemodynamic monitoring according to claim 1, characterized in that: The push injection pump is a flow pump, and a flow meter is provided at the outlet end of the delivery pipe. The flow meter obtains flow data of the medium in the delivery pipe at the outlet end and sends it to the controller.

6. A method for operating the physiological saline push injection device for hemodynamic monitoring according to any one of claims 1 to 5, characterized in that: The following steps are involved: The inlet end of the delivery tube obtains and delivers the physiological saline solution, and the cooling mechanism cools the physiological saline solution in the delivery tube; The push pump drives the physiological saline to flow along the delivery tube and pushes the cooled physiological saline to the outlet end, and the first temperature sensor and the second temperature sensor measure the temperature of the physiological saline at the corresponding position; The controller adjusts the power of the refrigeration mechanism according to the first temperature sensor data, and adjusts the power of the refrigeration mechanism and / or the pumping flow of the injection pump according to the second temperature sensor data, so that the outlet end outputs physiological saline that meets the temperature requirement.

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