Biopharmaceutical waste gas treatment monitoring device based on laser-induced breakdown spectroscopy

Abstract

The application discloses a biopharmaceutical waste gas treatment monitoring device based on laser-induced breakdown spectroscopy, and relates to the technical field of waste gas treatment monitoring. When monitoring, a plurality of devices are used to reasonably and effectively control the gas pressure in the monitoring cavity, thereby ensuring the safety of the whole process. Before monitoring the waste gas sample, the sample does not need to be treated, and the application can be directly used to treat and monitor the waste gas in real time. The spectrometer in the device receives the spectrum emitted by the waste gas after laser irradiation. Through the machine learning method, the composition and content of the pollutants in the waste gas can be quickly obtained, and the time and cost of manual analysis and calculation are reduced. The instrument can send data to external equipment through a Bluetooth module, the data can be saved to a built-in chip and a cloud, and users can obtain information such as whether the waste gas meets the emission standard in real time through a mobile device such as a mobile phone.

Description

Technical Field

[0001] This invention relates to the field of waste gas treatment monitoring technology, specifically a biopharmaceutical waste gas treatment monitoring device based on laser-induced breakdown spectroscopy. Background Technology

[0002] In recent years, with the development of science and technology and the significant improvement of people's living standards, the pursuit of health quality has been increasing, and the scale of the biopharmaceutical industry has expanded rapidly. However, in the biopharmaceutical industry, both the experimental research process and the actual production process generate a large amount of polluting and harmful gases. Due to the special nature of drugs, the components of various varieties are completely different, and the acidity and alkalinity of the exhaust gas are also unstable, which poses great harm to water bodies, structures, and crops. In addition, the concentration of pharmaceutical exhaust gas is very high, causing huge pollution to the local air. Therefore, the treatment and monitoring of the components of biopharmaceutical exhaust gas to ensure that they meet the standards is of great significance.

[0003] Laser-induced breakdown spectroscopy (LIBS) is a highly advanced optical detection technology that can theoretically detect the composition of substances in any state, including gaseous, solid, and liquid phases. The basic principle of this technology is to use an ultrashort pulse laser, focused onto the sample surface through a lens, to form a high-temperature plasma within a short time. Subsequently, a spectrometer analyzes the received plasma spectrum and compares it with a comparative spectral database to determine the sample's composition and content. LIBS technology is a laser-based analytical technique that eliminates the need for any sample pretreatment, offering unique advantages. Furthermore, it boasts high analysis speed, enabling real-time in-situ monitoring and measurement with minimal damage to the sample. Therefore, this paper proposes a monitoring device for biopharmaceutical waste gas treatment based on laser-induced breakdown spectroscopy. Summary of the Invention

[0004] To address the shortcomings mentioned in the background art, the present invention aims to provide a biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy.

[0005] The objective of this invention can be achieved through the following technical solution: a biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy, comprising a waste gas treatment system, a spectral acquisition system, an analysis and processing system, a central control system, and a monitoring and judgment system.

[0006] The exhaust gas treatment system includes an exhaust gas treatment device and an exhaust gas inlet. An exhaust gas inlet is provided below the exhaust gas treatment device. The exhaust gas treatment device is used to treat exhaust gas, and the exhaust gas inlet is used to introduce exhaust gas into the exhaust gas treatment device.

[0007] The spectral acquisition system includes a high-power laser power interface, a laser pump source, a laser resonant cavity, a reflector, a variable laser focuser, a laser beam, a spectral probe, an ICCD detector, and a spectrometer. A high-power laser interface is located below the laser pump source. A laser resonant cavity is located on one side of the laser pump source. A reflector is mounted on one side of the laser resonant cavity. A variable laser focuser is fixedly mounted on the reflector. A laser beam is mounted on the variable laser focuser. An ICCD detector is located above the laser beam. A spectrometer is located on one side of the ICCD detector. An external high-power power supply provides energy to the laser pump source. The laser pump source connects to the laser resonant cavity to generate a high-energy laser beam. After the optical path is changed by the reflector, the variable laser focuser focuses the laser beam onto the waste gas to be tested within the cavity. The spectral probe receives the emitted spectrum and is coupled to an optical fiber to transmit the acquired optical signal to the spectrometer. The ICCD detector delay time parameter is optimized by an internal controller equipped with a time delay device. In this embodiment, this design improves detection accuracy.

[0008] The central control system includes a central control unit, whose function is to control the interaction between the various devices.

[0009] The analysis and processing system consists of a built-in chip in the central control unit;

[0010] The monitoring and judgment system includes a gas pressurization device, a gas flow monitoring device, an airflow balancing device, and a gas congestion monitoring device. The gas pressurization device is connected to the gas flow monitoring device, the gas flow monitoring device is connected to the airflow balancing device, and the airflow balancing device is connected to the gas congestion monitoring device. The gas pressurization device is used to increase the gas pressure, the gas flow monitoring device is used to monitor the airflow, the airflow balancing device is used to stabilize the airflow, and the gas congestion monitoring device is used to detect whether the airflow is congested.

[0011] Furthermore, the central control unit is connected to a booster, a high-pressure air pump, a laser, a gas flow detection device, a gas congestion monitoring device, a variable laser focuser, a spectrometer, and a Bluetooth module.

[0012] Furthermore, the waste gas treatment device is connected to a non-monitoring gas pipeline, and a waste gas outlet is provided on one side of the non-monitoring gas pipeline.

[0013] Furthermore, the airflow equalization device is provided with a gas detection chamber, and a high-pressure gas injection head is provided on one side of the airflow equalization device, with a high-pressure gas pipeline connected to one side of the high-pressure gas injection head.

[0014] Furthermore, the high-pressure gas pipeline is connected to a high-pressure gas pump.

[0015] The beneficial effects of this invention are:

[0016] This invention enables real-time and rapid monitoring of the composition and content of pollutants in biopharmaceutical waste gas, effectively reducing the pollution and harm of harmful components in the waste gas to the air, and monitoring in real time whether emissions meet standards, greatly improving the efficiency and accuracy of waste gas treatment and monitoring. During treatment and monitoring, multiple devices are used to reasonably and effectively control the gas pressure in the monitoring chamber, ensuring the safety of the entire process. Before monitoring waste gas samples, no sample treatment is required; the invention can be used directly to treat and monitor the waste gas in real time. The spectrometer in the device receives the spectrum emitted by the waste gas after laser irradiation, and through machine learning methods, the composition and content of pollutants in the waste gas can be quickly obtained, reducing the time and cost of manual analysis and calculation. The instrument can send data to external devices via Bluetooth module, and the data can be saved to the built-in chip and the cloud. Users can obtain information such as whether the waste gas meets emission standards in real time through mobile devices such as mobile phones. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0019] Figure 2 This is a schematic diagram of the airflow distribution within the airflow equalization device of the present invention;

[0020] Figure 3 This is a schematic diagram of the airflow equalization device of the present invention.

[0021] The attached diagram lists the components represented by each number as follows:

[0022] 1. Exhaust gas treatment device; 2. Exhaust gas inlet; 3. Gas pressurization device; 4. Gas flow monitoring device; 5. Airflow equalization device; 6. High-power laser power interface; 7. Laser pump source; 8. Laser resonant cavity; 9. Reflector; 10. Variable laser focuser; 11. Laser beam; 12. Spectrometer head; 13. High-pressure gas jet head; 14. High-pressure gas pipeline; 15. High-pressure gas pump; 16. ICCD detector; 17. Spectrometer; 18. Gas congestion monitoring device; 19. Bluetooth module; 20. Central control unit; 21. Gas detection cavity; 22. Non-monitored gas pipeline; 23. Exhaust gas outlet. Detailed Implementation

[0023] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0024] like Figure 1-3 As shown, the biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy includes a waste gas treatment system, a spectral acquisition system, an analysis and processing system, a central control system, and a monitoring and judgment system.

[0025] The exhaust gas treatment system includes an exhaust gas treatment device 1 and an exhaust gas inlet 2. The exhaust gas inlet 2 is located below the exhaust gas treatment device 1. It should be further explained that, in the specific implementation process, the exhaust gas treatment device 1 is used to treat the exhaust gas, and the exhaust gas inlet 2 is used to introduce the exhaust gas into the exhaust gas treatment device 1.

[0026] The spectral acquisition system includes a high-power laser interface 6, a laser pump source 7, a laser resonant cavity 8, a reflector 9, a variable laser focuser 10, a laser beam 11, a spectral detector 12, an ICCD detector 16, and a spectrometer 17. A high-power laser interface is located below the laser pump source 7. The laser resonant cavity 8 is located on one side of the laser pump source 7. A reflector 9 is mounted on one side of the laser resonant cavity 8. A variable laser focuser 10 is fixedly mounted on the reflector 9. A laser beam 11 is mounted on the variable laser focuser 10. An ICCD detector 16 is located above the laser beam 11. A spectrometer 17 is provided on one side. It should be further explained that in the specific implementation process, an external high-power power supply provides energy to the laser pump source 7. The laser pump source 7 is connected to the laser resonant cavity 8 to generate a high-energy laser beam 11. After the optical path is changed by the reflector 9, the laser beam 11 is focused on the waste gas to be tested in the cavity by the variable laser focuser 10. The spectral probe 12 receives the emitted spectrum. The spectral probe 12 is coupled to the optical fiber and transmits the collected optical signal to the spectrometer 17. The delay time parameter of the ICCD detector 16 is optimized by the internal controller equipped with a time delay device. In this embodiment, this design is used to improve the detection accuracy.

[0027] The central control system includes a central control unit 20. It should be further explained that, in the specific implementation process, the function of the central control unit 20 is to control the mutual operation between the various devices.

[0028] The analysis and processing system consists of a built-in chip in the central control unit 20.

[0029] The monitoring and judgment system includes a gas pressurization device 3, a gas flow monitoring device 4, an airflow balancing device 5, and a gas congestion monitoring device 18. The gas pressurization device 3 is connected to the gas flow monitoring device 4, the gas flow monitoring device 4 is connected to the airflow balancing device 5, and the airflow balancing device 5 is connected to the gas congestion monitoring device 18. The gas pressurization device 3 is used to increase the gas pressure, the gas flow monitoring device 4 is used to monitor the airflow, the airflow balancing device 5 is used to stabilize the airflow, and the gas congestion monitoring device 18 is used to detect whether the airflow is congested.

[0030] It should be further explained that, in the specific implementation process, the central control unit 20 is connected to the booster, high-pressure air pump 15, laser, gas flow detection device, gas congestion monitoring device 18, variable laser focuser 10, spectrometer 17 and Bluetooth module 19.

[0031] It should be further explained that, in the specific implementation process, the waste gas treatment device 1 is connected to a non-monitoring gas pipeline 22, and a waste gas outlet 23 is opened on one side of the non-monitoring gas pipeline 22.

[0032] It should be further explained that, in the specific implementation process, the airflow equalization device 5 is provided with a gas detection chamber 21, and a high-pressure gas injection head 13 is provided on one side of the airflow equalization device 5, and a high-pressure gas pipeline 14 is connected to one side of the high-pressure gas injection head 13.

[0033] It should be further explained that, in the specific implementation process, the high-pressure gas pipeline 14 is connected to the high-pressure gas pump 15.

[0034] It needs further explanation that, in the specific implementation process, such as Figure 2 As shown, when the exhaust gas enters the detection chamber, the gas velocity is faster in the middle of the chamber and slower near the chamber wall. Two mesh airflow equalization devices 5 are used to change the gas velocity distribution, so that the gas velocity distribution is uniform between the two airflow equalization devices 5.

[0035] like Figure 3 As shown, the gas equalization device 5 has a mesh structure with centrally symmetrical mesh holes that allow airflow to pass through. The holes in the central part are smaller in diameter, while those at the edges are larger in diameter, which ensures that the gas velocity is evenly distributed throughout the flow.

[0036] Working principle: Turn on the instrument, set the monitoring mode and requirements, and introduce biopharmaceutical waste gas into the waste gas treatment device 1 through waste gas inlet 2. A small amount of treated gas enters the gas flow monitoring device 4 through the booster pipe, while the remaining waste gas is discharged through the non-monitored gas pipeline 22. Before the gas to be monitored enters the detection chamber, the gas flow detection device connects to the central control unit 20 to control the parameters of the booster pipe in real time to ensure safe gas pressure and gas flow rate within the gas chamber. Then, the gas flow rate is evenly distributed within the detection chamber by the gas equalization devices on both sides of the chamber. An external high-power power supply provides energy to the laser pump source 7. The laser pump source 7 connects to the laser resonant cavity 8 to generate a high-energy laser beam 11. After the optical path is changed by the reflector 9, the laser beam 11 is focused onto the waste gas to be tested within the chamber using a variable laser focuser 10. Furthermore, the central control unit 20 controls the variable laser focuser 10. The gas at different locations within the cavity is measured by continuously changing the focal position, improving detection accuracy. The spectral probe 12 receives the emitted spectrum and is coupled to an optical fiber, transmitting the collected light signal to the spectrometer 17. The delay time parameter of the ICCD detector 16 is optimized by an internal controller equipped with a time delay device, improving detection accuracy. The spectrometer 17 transmits the spectral data to the central control unit 20, compares it with the instrument's database, and transmits detailed monitoring results in real-time to computers and mobile phones via Bluetooth module 19, while simultaneously storing them in the built-in chip and the cloud. The detected gas passes through a gas congestion monitoring device 18, which transmits gas flow information to the central control unit 20. If gas congestion occurs, monitoring is immediately stopped. The monitored exhaust gas mixes with the undetected exhaust gas and is discharged from the exhaust outlet 23. During monitoring, the central control unit 20 controls the high-pressure gas pump 15 to periodically spray clean high-pressure gas onto the spectral probe 12, removing impurities near the probe and improving monitoring accuracy.

[0037] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed invention.

Claims

1. A biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy, characterized in that, It includes an exhaust gas treatment system, a spectral acquisition system, an analysis and processing system, a central control system, and a monitoring and judgment system; The exhaust gas treatment system includes an exhaust gas treatment device (1) and an exhaust gas inlet (2), with the exhaust gas inlet (2) located below the exhaust gas treatment device (1). The spectral acquisition system includes a high-power laser power interface (6), a laser pump source (7), a laser resonant cavity (8), a reflector (9), a variable laser focuser (10), a laser beam (11), a spectral probe (12), an ICCD detector (16), and a spectrometer (17). The high-power laser power interface (6) is provided below the laser pump source (7). The laser resonant cavity (8) is provided on one side of the laser pump source (7). A reflector (9) is installed on one side of the laser resonant cavity (8). A variable laser focuser (10) is fixedly installed on the reflector (9). A laser beam (11) is provided on the variable laser focuser (10). An ICCD detector (16) is provided above the laser beam (11). A spectrometer (17) is provided on one side of the ICCD detector (16). The spectral probe (12) receives the emitted spectrum. The central control system includes a central control unit (20). The analysis and processing system consists of a built-in chip in the central control unit (20); The monitoring and judgment system includes a gas pressurization device (3), a gas flow monitoring device (4), a gas detection cavity (21), an airflow equalization device (5), and a gas congestion monitoring device (18). The gas pressurization device (3) is connected to the gas flow monitoring device (4), the gas flow monitoring device (4) is connected to the gas detection cavity (21), and the gas detection cavity (21) is connected to the gas congestion monitoring device (18). The gas treated by the waste gas treatment device (1) enters the gas flow monitoring device (4) through the gas pressurization device (3). The laser pump source (7) is connected to the laser resonant cavity (8) to generate a high-energy laser beam (11). After the optical path is changed by the reflector (9), the laser beam (11) is focused on the waste gas to be tested in the gas detection cavity (21) by the variable laser focuser (10). The airflow equalization device (5) is installed in the gas detection chamber (21). A high-pressure gas nozzle (13) is provided on one side of the airflow equalization device (5), and a high-pressure gas pipeline (14) is connected to one side of the high-pressure gas nozzle (13).

2. The biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy according to claim 1, characterized in that, The gas booster (3) is used to increase the pressure of the gas, the gas flow monitoring device (4) is used to monitor the airflow, the airflow balancing device (5) is used to stabilize the airflow, and the gas congestion monitoring device (18) is used to detect whether the airflow is congested.

3. The biopharmaceutical waste gas treatment monitoring device based on laser-induced breakdown spectrum according to claim 1, wherein the central control unit (20) is connected to a booster, a high-pressure air pump (15), a laser, a gas flow detection device, a gas congestion monitoring device (18), a variable laser focuser (10), a spectrometer (17), and a Bluetooth module (19).

4. The biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy according to claim 1, characterized in that, The waste gas treatment device (1) is connected to a non-monitoring gas pipeline (22), and a waste gas outlet (23) is provided on one side of the non-monitoring gas pipeline (22).

5. The biopharmaceutical waste gas treatment and monitoring device based on laser-induced breakdown spectroscopy according to claim 1, characterized in that, The high-pressure gas pipeline (14) is connected to the high-pressure gas pump (15).

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