PET image reconstruction method, device, equipment and storage medium

Abstract

The present invention relates to a PET image reconstruction method, device, equipment and storage medium, including: obtaining reconstruction sequence data and event time data; determining the start time of the reconstruction sequence data according to the event time data; obtaining mode data selected by a user, and performing decay correction on the reconstruction sequence data according to the start time, the event time data and the mode data. The present invention combines the event time data and the mode data in the PET reconstruction process to perform decay correction on the reconstruction sequence data, thereby simplifying the decay correction process of PET reconstruction in different scenarios.

Description

Technical Field

[0001] The present invention relates to the technical field of image reconstruction, and particularly relates to a PET image reconstruction method, apparatus, device, and storage medium. Background Art

[0002] In PET (Positron Emission Tomography) scanning, after a radioactive pharmaceutical enters the patient's body through injection, inhalation, ingestion, etc., due to the physical properties of the radioactive pharmaceutical and the biological molecular properties, the radioactive pharmaceutical accumulates in specific parts of the human body, and scanning imaging is performed by a positron emission imaging device. Myocardial perfusion imaging is performed by injecting a radioactive nuclide that can be taken up by myocardial cells, and using a positron emission imaging device to detect the distribution of radioactive nuclides in different parts of the myocardium, and performing multi-angle tomographic imaging to diagnose heart diseases. The radioactive nuclides used for positron collection are all short half-life nuclides. During the PET collection process, due to the long sampling period, the nuclides may have decayed by several half-lives. During PET reconstruction, correction for the natural decay of the radioactive nuclides needs to be performed. Currently, there are two decay correction modes, namely the START mode and the ADMIN mode. The starting reference time for performing decay correction is the sequence start time, which is very close to the acquisition time of the first bed.

[0003] During the above reconstruction process, affected by some factors, it may lead to the situation that the sequence start time of the reconstructed sequence data is inconsistent with the acquisition time, drug injection time, etc. Therefore, it is necessary to correct the sequence start time of the reconstructed sequence data. For example, during PET / CT (Positron Emission Tomography / Computed Tomography) scanning, when the user clicks the sequence start button, but does not click the acquisition button of the CTbox (it should be noted that the CTbox is a CT control box and can be clicked multiple times to trigger CT acquisition), resulting in a too large gap between the sequence start time and the acquisition start time of the reconstructed sequence data; or, during myocardial perfusion, the patient is scanned first, and then the drug is injected during the scanning process. At this time, if the START mode is selected for decay correction on the interface, it will cause the correction baseline of the drug to be too early. Therefore, how to correct the sequence start time of the reconstructed sequence data in PET scanning and perform efficient decay correction on the reconstructed sequence data is an urgent problem to be solved. Summary of the Invention

[0004] In view of this, it is necessary to provide a PET image reconstruction method, apparatus, device and storage medium to overcome the problem in the prior art that the reconstruction sequence data in PET scanning cannot be efficiently decay-corrected.

[0005] The present invention provides a PET image reconstruction method, including:

[0006] Obtain reconstruction sequence data and event time data;

[0007] Determine the start time of the reconstruction sequence data according to the event time data;

[0008] Obtain the mode data selected by the user, and perform decay correction on the reconstruction sequence data according to the start time, the event time data and the mode data.

[0009] Further, the event time data includes the scan acquisition time and the drug injection time, and the determining the start time of the reconstruction sequence data according to the event time data includes:

[0010] Determine the start time according to the comparison result between the scan acquisition time and the drug injection time.

[0011] Further, the determining the start time according to the comparison result between the scan acquisition time and the drug injection time includes:

[0012] If the scan acquisition time is earlier than the drug injection time, determine the start time as the drug injection time.

[0013] Further, the determining the start time according to the comparison result between the scan acquisition time and the drug injection time includes:

[0014] If the scan acquisition time is later than the drug injection time, determine the start time as the scan acquisition time.

[0015] Further, the performing decay correction on the reconstruction sequence data according to the start time, the event time data and the mode data includes:

[0016] Judge the decay correction mode selected by the user at the current moment according to the mode data;

[0017] For different decay correction modes, perform decay correction on the reconstruction sequence data according to the start time and the event time data.

[0018] Further, the performing decay correction on the reconstruction sequence data according to the start time and the event time data for different decay correction modes includes:

[0019] If the decay correction mode is the first mode, determine a correction reference time for the reconstructed sequence data according to the start time.

[0020] Further, for different decay correction modes, performing decay correction on the reconstructed sequence data according to the start time and the event time data includes:

[0021] If the decay correction mode is the second mode, determine a correction reference time for the reconstructed sequence data according to the drug injection time.

[0022] The present invention also provides a PET image reconstruction device, including:

[0023] An acquisition unit for acquiring reconstructed sequence data and event time data;

[0024] A processing unit for determining a start time of the reconstructed sequence data according to the event time data;

[0025] A correction unit for acquiring mode data selected by a user, and performing decay correction on the reconstructed sequence data according to the start time, the event time data, and the mode data.

[0026] The present invention also provides a PET image reconstruction device, including a memory and a processor, where the memory stores an executable program, and when the processor executes the executable program, the above-mentioned PET image reconstruction method is implemented.

[0027] The present invention also provides a computer-readable storage medium, on which an executable program is stored, and when the executable program is executed by a processor, the above-mentioned PET image reconstruction method is implemented.

[0028] Compared with the prior art, the beneficial effects of the present invention include: First, effectively obtain the reconstructed sequence data and event time data; then, according to the event time data, determine the sequence of occurrence of corresponding drug injection, scan acquisition, etc., fully considering the influencing factors of different events occurring successively during the scanning process, so as to effectively determine the starting time of the reconstructed sequence data and ensure the accuracy of the reconstructed sequence data; furthermore, in combination with the mode data selected by the user, consider the impact of the selected mode on calibration, and then combine the starting time and event time data to comprehensively distinguish various situations, fully considering the influence of different factors. Before reconstruction starts, correct the starting time of the reconstructed sequence data, use the starting time of the reconstructed sequence as the time for decay correction to be saved and transmitted, thereby pre-adjusting the starting time point of decay correction, and transmitting the starting time together with the PET raw data obtained under this acquisition sequence to the reconstruction module for decay correction. For different situations, ensure the efficiency and accuracy of calibration, thereby improving the accuracy of the reconstructed image. In summary, the present invention can be compatible with most clinical scanning processes and also compatible with the scanning scenarios of myocardial perfusion. For example, in the field of Positron Emission Tomography / Computed Tomography (PET / CT) or Positron Emission Tomography / Magnetic Resonance Imaging (PET-MRI), during the PET reconstruction process, in combination with event time data and mode data, perform decay correction on the reconstructed sequence data, simplifying the decay correction process of PET reconstruction in different scenarios. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 It is a schematic flowchart of an embodiment of the PET image reconstruction method provided by the present invention;

[0030] Figure 2 Provided by the present invention Figure 1 It is a schematic flowchart of an embodiment of step S103 in

[0031] Figure 3 It is a schematic structural diagram of an embodiment of the PET image reconstruction device provided by the present invention;

[0032] Figure 4 It is a schematic structural diagram of an embodiment of the PET image reconstruction device provided by the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0033] The preferred embodiments of the present invention will be specifically described below with reference to the accompanying drawings. The accompanying drawings form a part of this application and are used together with the embodiments of the present invention to explain the principles of the present invention, rather than to limit the scope of the present invention.

[0034] In the description of the present invention, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the meaning of "a plurality" is at least two, such as two, three, etc., unless otherwise specifically defined.

[0035] In the description of the present invention, referring to "embodiment" means that the specific features, structures or characteristics described in connection with the embodiment may be included in at least one embodiment of the present invention. The phrase appearing at various positions in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment mutually exclusive with other embodiments. Those skilled in the art will explicitly and implicitly understand that the described embodiments may be combined with other embodiments.

[0036] The present invention provides a PET image reconstruction method, device, equipment and storage medium, which can distinguish different scanning situations based on event time data and pattern data, and perform decay correction in a targeted manner, providing a new idea for further improving the accuracy of PET reconstruction.

[0037] Before describing the embodiments, the meanings of relevant terms are explained as follows:

[0038] Myocardial perfusion scan: Also known as myocardial perfusion imaging, it can measure the blood content in the heart muscle at rest and during activity. It is often used to find the causes that may lead to angina (such as chest pain or tenderness), and can also be used to check whether some parts of the heart do not receive enough blood after a heart attack, or to find out how much myocardial damage has been caused by a heart attack. During this process, the doctor will first inject a special test drug (radioactive tracer) into the patient's vein and take pictures of the heart using a "camera". The tracer will enter the heart muscle through the blood, and the parts with good blood flow can absorb the tracer. The parts that do not absorb the tracer may not have enough blood or have been damaged due to a heart attack;

[0039] PET Reconstruction: In positron emission tomography (PET) scans, radioactive pharmaceuticals are administered to patients through injection, inhalation, or ingestion. Subsequently, due to the physical properties and biomolecular properties of the radioactive pharmaceuticals, they accumulate in specific parts of the human body. Scanning and imaging are performed using a positron emission imaging device. Since the positron emission imaging device has a limited axial length and cannot cover all the parts of the human body that need to be imaged in a single scan, multiple bed scans are required. During multiple bed scans, the patient lies on a hospital bed. After completing the scan of the current bed, the hospital bed moves inward (outward) by the distance of one bed for the scan of the next bed. During the scanning process, data reconstruction needs to be performed on the multiple reconstructed sequence data generated from multiple beds to obtain the final scanned image.

[0040] Based on the description of the above technical terms, during the PET reconstruction process, the user can select the decay correction method for the next reconstructed sequence on the reconstruction parameter panel of the scanning interface.

[0041] Currently, there are two decay correction modes, the START mode and the ADMIN mode. The starting reference time for decay correction during reconstruction is the sequence start time, which is very close to the acquisition time of the first bed. When the user clicks the sequence start button but does not click the acquisition button on the data acquisition start panel, the gap between the sequence start time and the acquisition start time becomes too large. In addition, in the process of myocardial perfusion, the patient first undergoes a scan and then injects drugs during the scan. At this time, if the START mode is selected on the interface for decay correction, it will cause the correction baseline of the drug to be too early. The above problems have no impact on the calculation of SUV (standard uptake value) in the scenario of multiple reconstructions after data cutting for the same raw data, but will lead to inconsistencies in multiple reconstructed sequences when using the unit of Bq / ml (it should be noted that Bq / ml is the unit method for calculating SUV by the PET scanning device, the activity density of the region).

[0042] The following will separately elaborate on specific embodiments in detail:

[0043] An embodiment of the present invention provides a PET image reconstruction method, combined with Figure 1 to see, Figure 1 is a schematic flowchart of an embodiment of the PET image reconstruction method provided by the present invention, including steps S101 to S103, where:

[0044] In step S101, reconstructed sequence data and event time data are obtained;

[0045] In step S102, according to the event time data, the start time of the reconstructed sequence data is determined;

[0046] In step S103, in the set mode, decay correction is performed on the reconstructed sequence data according to the start time and the event time data.

[0047] In the embodiment of the present invention, first, the reconstructed sequence data and the event time data are effectively obtained; then, according to the event time data, the sequence of occurrence of corresponding drug injection, scan acquisition, etc. times is determined, and the influencing factors of different events occurring successively during the scanning process are fully considered, so as to effectively determine the start time of the reconstructed sequence data and ensure the accuracy of the reconstructed sequence data; furthermore, in combination with the mode data selected by the user, considering the influence of the mode selected by the user on the correction, and then in combination with the start time and the event time data, various situations are comprehensively distinguished, the influence of different factors is fully considered, and decay correction is performed on the reconstructed sequence data. For different situations, the efficiency and accuracy of the correction are ensured, thereby improving the accuracy of the reconstructed image. Among them, the set mode can be the mode selected by the user, such as the START mode or the ADMIN mode.

[0048] In a specific embodiment of the present invention, during myocardial perfusion scanning, multiple reconstructed sequence data generated by scanning are reconstructed. The multiple reconstructed sequence data need to ensure that the calibration reference time is consistent in order to generate accurate reconstructed images. For example, after injecting a small amount of 18 F-FDG into the human body through intravenous injection and then starting the scan, and injecting drug Rb-82 during the scan. If the uptake of drug Rb-82 by the heart is to be detected, since the time when the patient injects drug Rb-82 is later than the data acquisition time, if the scan start time is used as the start time of the reconstructed sequence, it will cause the calibration baseline of drug Rb-82 to be too early, so the start time of the reconstructed sequence data needs to be corrected. Among them, the reconstructed sequence data are PET raw data collected under the reconstructed sequence, and the event time data include the time information about the start of drug injection and the start of data acquisition, that is, the drug injection time and the scan acquisition time. Obtaining the reconstructed sequence data, the start time of the reconstructed sequence and combining the reconstruction algorithm can obtain the PET reconstructed image.

[0049] As a preferred embodiment, the above step S202 includes:

[0050] Determine the start time according to the comparison result of the scan acquisition time and the drug injection time.

[0051] In the embodiment of the present invention, by comparing the scan acquisition time and the drug injection time, the sequence of scan acquisition and drug injection is determined, so as to determine the start time of the corresponding reconstructed sequence data for different situations.

[0052] As a preferred embodiment, the above determining the start time according to the comparison result of the scan acquisition time and the drug injection time specifically includes:

[0053] If the scanning acquisition time is earlier than the drug injection time, the starting time is determined as the drug injection time.

[0054] In the embodiment of the present invention, when the scanning acquisition time is earlier than the drug injection time, the starting time of the reconstructed sequence data is set as the drug injection time. At this time, starting from the drug injection time, the accuracy of the reconstructed sequence data is ensured.

[0055] As a preferred embodiment, determining the starting time according to the comparison result of the scanning acquisition time and the drug injection time specifically includes:

[0056] If the scanning acquisition time is later than the drug injection time, the starting time is determined as the scanning acquisition time.

[0057] In the embodiment of the present invention, when the scanning acquisition time is later than the drug injection time, the starting time of the reconstructed sequence data is set as the scanning acquisition time. At this time, starting from the scanning acquisition time, the accuracy of the reconstructed sequence data is ensured.

[0058] As a preferred embodiment, combined with Figure 2 to see, Figure 2 provided by the present invention Figure 1 is a schematic flowchart of an embodiment of step S103 in the present invention. The above step S103 includes steps S201 to S202, wherein:

[0059] In step S201, according to the mode data, determine the decay correction mode selected by the user at the current moment;

[0060] In step S202, for different decay correction modes, perform decay correction on the reconstructed sequence data according to the starting time and the event time data.

[0061] In the embodiment of the present invention, the user-selected mode data is used to distinguish different mode states, so as to perform decay correction on the reconstructed sequence data in a targeted manner under different decay correction modes.

[0062] As a preferred embodiment, the above step S202 specifically includes:

[0063] If the decay correction mode is the first mode, determine the correction reference time of the reconstructed sequence data according to the starting time.

[0064] In the embodiment of the present invention, the first mode is preferably the START mode. When the decay correction mode is the START mode, the correction reference time of the reconstructed sequence data is set as the starting time. At this time, starting from the starting time as the correction reference time, the accuracy of the reconstructed sequence data is ensured.

[0065] As a preferred embodiment, step S202 specifically includes:

[0066] If the decay correction mode is the second mode, determine the correction reference time of the reconstructed sequence data according to the drug injection time.

[0067] In the embodiment of the present invention, the second mode is preferably the ADMIN mode. When the decay correction mode is the ADMIN mode, the correction reference time of the reconstructed sequence data is set as the drug injection time. At this time, with the drug injection time as the correction reference time, the accuracy of the reconstructed sequence data is ensured.

[0068] The technical solution of the present invention will be described more specifically below with a specific application example:

[0069] First step, when the reconstruction task is started, perform a correction process on the start time of the reconstructed sequence;

[0070] Second step, when the acquisition time is earlier than the drug injection time, directly fill in the start time of the reconstructed sequence as the start time of the drug injection at this time; when the acquisition time is later than the drug injection time, modify the value of the start time of the reconstructed sequence to the acquisition time at this time;

[0071] Third step, transfer the above information to the reconstruction module. At the same time, continuously read the disk raw data file of the PET raw data collected under this acquisition sequence and transfer it to the reconstruction module together;

[0072] Fourth step, after the reconstruction is started, obtain the decay correction mode of the parameters configured by the user interface, whether it is ADMIN or START; if it is the START mode, the base point time of the decay correction is the start time of the reconstructed sequence; if it is the ADMIN mode, the starting reference time of the decay correction is the drug injection time.

[0073] It should be noted that the above rules ensure that regardless of whether the entire raw data is cut and reconstructed multiple times, their starting reference times are the same. As a result, the decay correction factors of the same acquisition and different reconstruction results will meet the expectations. By comparing the relationship between the scan acquisition time and the drug injection time before the reconstruction starts, the time used for decay correction is saved and transferred using the start time of the reconstructed sequence, thereby pre-adjusting the starting time point of the decay correction. Such an adjustment can not only be compatible with most clinical scan processes but also be compatible with the scan scenario of myocardial perfusion. In summary, this time is set before the reconstruction starts, simplifying the decay correction process of the reconstruction algorithm module in different scenarios.

[0074] The embodiment of the present invention also provides a PET image reconstruction device, combined with Figure 3 seen Figure 3Schematic structural diagram of an embodiment of the PET image reconstruction device provided by the present invention. The PET image reconstruction device 300 includes:

[0075] An acquisition unit 301, configured to acquire reconstruction sequence data and event time data;

[0076] A processing unit 302, configured to determine the start time of the reconstruction sequence data according to the event time data;

[0077] A correction unit 303, configured to acquire the mode data selected by the user, and perform decay correction on the reconstruction sequence data according to the start time, the event time data, and the mode data.

[0078] For more specific implementation manners of each unit of the PET image reconstruction device, reference may be made to the description of the above PET image reconstruction method, and it has similar beneficial effects, which will not be elaborated herein.

[0079] An embodiment of the present invention further provides a computer-readable storage medium, on which a computer program is stored. When the program is executed by a processor, the above-mentioned PET image reconstruction method is implemented.

[0080] Generally speaking, computer instructions for implementing the method of the present invention can be carried by any combination of one or more computer-readable storage media. A non-transitory computer-readable storage medium may include any computer-readable medium except for a signal propagating temporarily itself.

[0081] The computer-readable storage medium may be, for example, but not limited to, an electrical, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any combination of the above. More specific examples (non-exhaustive list) of the computer-readable storage medium include: an electrical connection having one or more wires, a portable computer disk, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber, a portable compact disk read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the above. In this document, the computer-readable storage medium may be any tangible medium that contains or stores a program, and the program can be used by or combined with an instruction execution system, apparatus, or device.

[0082] The computer program code for performing the operations of the present invention can be written in one or more programming languages or combinations thereof. The programming languages include object-oriented programming languages such as Java, Smalltalk, C++, and also include conventional procedural programming languages such as the "C" language or similar programming languages. In particular, the Python language suitable for neural network computing and platform frameworks based on TensorFlow, PyTorch, etc. can be used. The program code can be executed entirely on the user's computer, partially on the user's computer, executed as an independent software package, partially on the user's computer and partially on a remote computer, or entirely on a remote computer or server. In the case of a remote computer, the remote computer can be connected to the user's computer through any type of network, including a local area network (LAN) or a wide area network (WAN), or can be connected to an external computer (for example, by connecting through an Internet service provider via the Internet).

[0083] An embodiment of the present invention also provides a PET image reconstruction device. In combination with Figure 4 viewed as Figure 4 FIG. 7 is a schematic structural diagram of an embodiment of the PET image reconstruction device provided by the present invention. The PET image reconstruction device 400 includes a processor 401, a memory 402, and a computer program stored in the memory 402 and executable on the processor 401. When the processor 401 executes the program, the above-described PET image reconstruction method is implemented.

[0084] As a preferred embodiment, the above PET image reconstruction device 400 further includes a display 403 for displaying the data processing result after the processor 401 executes the PET image reconstruction method.

[0085] Exemplarily, the computer program can be divided into one or more modules / units. One or more modules / units are stored in the memory 402 and executed by the processor 401 to complete the present invention. One or more modules / units can be a series of computer program instruction segments capable of performing specific functions, and these instruction segments are used to describe the execution process of the computer program in the PET image reconstruction device 400. For example, the computer program can be divided into the acquisition unit 301, the processing unit 302, and the correction unit 303 in the above embodiment. The specific functions of each unit are as described in the first embodiment or the second embodiment, and will not be elaborated here one by one.

[0086] The PET image reconstruction device 400 can be a desktop computer with an adjustable camera module, a notebook, a palm computer, a smart phone, or other devices.

[0087] Among them, the processor 401 may be an integrated circuit chip with signal processing capabilities. The above-mentioned processor 401 may be a general-purpose processor, including a central processing unit (CPU), a network processor (NP), etc.; it may also be a digital signal processor (DSP), an application specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components. It can implement or execute the various methods, steps, and logic block diagrams disclosed in the embodiments of the present invention. The general-purpose processor may be a microprocessor or the processor may also be any conventional processor, etc.

[0088] Among them, the memory 402 may be, but is not limited to, a random access memory (RAM), a read-only memory (ROM), a programmable read-only memory (PROM), an erasable programmable read-only memory (EPROM), an electrically erasable programmable read-only memory (EEPROM), etc. Among them, the memory 402 is used to store programs. After the processor 401 receives an execution instruction, it executes the program. The methods defined by the processes disclosed in any of the embodiments of the present invention described above can be applied to or implemented by the processor 401.

[0089] Among them, the display 403 may be an LCD display screen or an LED display screen. For example, the display screen on a mobile phone.

[0090] It can be understood that Figure 4 The structure shown is only a schematic structural diagram of the PET image reconstruction device 400, and the PET image reconstruction device 400 may also include more or less components than Figure 4 shown. Figure 4 Each component shown in may be implemented by hardware, software, or a combination thereof.

[0091] According to the computer-readable storage medium and the PET image reconstruction device provided in the above embodiments of the present invention, they can be implemented with reference to the content specifically described in the PET image reconstruction method implemented according to the present invention, and have beneficial effects similar to those of the PET image reconstruction method described above, which will not be elaborated here.

[0092] The present invention discloses a PET image reconstruction method, device, equipment and storage medium. First, the reconstruction sequence data and event time data are effectively acquired; then, according to the event time data, the sequence of occurrence of corresponding drug injection, scan acquisition and other times is determined, and the influencing factors of different events occurring successively during the scan are fully considered, so as to effectively determine the start time of the reconstruction sequence data and ensure the accuracy of the reconstruction sequence data; furthermore, in combination with the mode data selected by the user, considering the influence of the mode selected by the user on the correction, and then combining the start time and event time data, various situations are comprehensively distinguished, and the influence of different factors is fully considered, and the decay correction is performed on the reconstruction sequence data. For different situations, the efficiency and accuracy of the correction are ensured, thereby improving the accuracy of the reconstructed image.

[0093] The technical solution of the present invention can be compatible with most clinical scan processes and also compatible with the scan scenario of myocardial perfusion. During the PET reconstruction process, in combination with the event time data and mode data, the decay correction is performed on the reconstruction sequence data, which simplifies the decay correction process of PET reconstruction in different scenarios.

[0094] The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any changes or substitutions that can be easily thought of by those skilled in the art within the technical scope disclosed by the present invention should be covered by the protection scope of the present invention.

Claims

1. A PET image reconstruction method, characterized in that: include: Acquiring reconstruction sequence data and event time data, wherein the event time data includes scan acquisition time and drug injection time; Determining the starting time of the reconstructed sequence data according to the event time data; acquiring mode data selected by a user, and performing decay correction on the reconstructed sequence data according to the start time, the event time data and the mode data; Wherein, determining the starting time of the reconstructed sequence data according to the event time data includes: Determining the start time according to a comparison result between the scan acquisition time and the drug injection time; If the scan acquisition time is earlier than the drug injection time, the start time is determined as the drug injection time; If the scan acquisition time is later than the drug injection time, the start time is determined as the scan acquisition time.

2. The PET image reconstruction method according to claim 1, characterized in that: The performing decay correction on the reconstructed sequence data according to the start time, the event time data and the mode data comprises: Determining the decay correction mode currently selected by the user according to the mode data; For different decay correction modes, decay correction is performed on the reconstructed sequence data according to the start time and the event time data.

3. The PET image reconstruction method according to claim 2, characterized in that: The performing decay correction on the reconstructed sequence data according to the start time and the event time data for different decay correction modes includes: If the decay correction mode is the first mode, a correction reference time for the reconstructed sequence data is determined according to the start time.

4. The PET image reconstruction method according to claim 2, characterized in that: The performing decay correction on the reconstructed sequence data according to the start time and the event time data for different decay correction modes includes: If the decay correction mode is the second mode, the correction reference time of the reconstructed sequence data is determined according to the drug injection time.

5. A PET image reconstruction device, characterized in that: include: An acquisition unit, used for acquiring reconstruction sequence data and event time data, wherein the event time data includes scan acquisition time and drug injection time; a processing unit, configured to determine a start time of the reconstructed sequence data according to the event time data; a correction unit, configured to obtain mode data selected by a user, and perform decay correction on the reconstructed sequence data according to the start time, the event time data and the mode data; Wherein, determining the starting time of the reconstructed sequence data according to the event time data includes: Determining the start time according to a comparison result between the scan acquisition time and the drug injection time; If the scan acquisition time is earlier than the drug injection time, the start time is determined as the drug injection time; If the scan acquisition time is later than the drug injection time, the start time is determined as the scan acquisition time.

6. A PET image reconstruction device, comprising a memory and a processor, wherein the memory stores an executable program, characterized in that: When the processor executes the executable program, the PET image reconstruction method according to any one of claims 1 to 4 is implemented.

7. A computer-readable storage medium having an executable program stored thereon, characterized in that: When the executable program is executed by a processor, the PET image reconstruction method according to any one of claims 1 to 4 is implemented.

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