A blood analyzer and a detection method thereof

By introducing a routine blood test module into the blood analyzer to dilute blood samples, the problem of inaccurate detection caused by excessively high concentrations of specific proteins is solved, thereby improving accuracy and efficiency, while avoiding multiple sampling.

CN115267238BActive Publication Date: 2025-12-05SHENZHEN DYMIND BIOTECH
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Patent Information

Application Number
CN202110483626.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-04-30
Publication Date
2025-12-05
Estimated Expiration
2041-04-30

AI Technical Summary

Technical Problem

Existing blood analyzers may produce inaccurate results for specific protein detection due to excessively high concentrations of certain proteins in the sample.

Method used

By introducing a routine blood test module into the blood analyzer to dilute blood samples, the sampling module sends the diluted sample to a specific protein detection module for detection. The routine blood test module is used as a dilution pool for the specific protein detection module to prevent the concentration of specific proteins from being too high.

Benefits of technology

It improves the accuracy and efficiency of blood analyzers, avoids the inconvenience of multiple samplings for patients, and enables simultaneous blood routine tests and specific protein tests.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The application discloses a blood analyzer and a detection method thereof, wherein the blood analyzer comprises a sampling module, a routine blood test module and a specific protein detection module; wherein: the sampling module is used for collecting a blood sample, and the blood sample is added to the routine blood test module; the routine blood test module is used for diluting the blood sample; the sampling module adds the diluted blood sample to the specific protein detection module; and the specific protein detection module is used for detecting specific proteins in the diluted blood sample. Through the above mode, the blood sample is diluted by the routine blood test module, so that the specific protein concentration of the blood sample is prevented from being too high, and the accuracy of the blood analyzer detection is improved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of blood detection, in particular to a blood analyzer and a detection method thereof. BACKGROUND

[0002] In hospital clinical examination, blood sampling of patients is usually performed and the collected blood samples are examined, various specific protein detection needs to be performed, and the detection results based on specific protein detection are used to determine the patient's condition.

[0003] The blood analyzer of the prior art includes a specific protein detection pool and a sample collection module, the sample collection module is used to collect samples and add the samples to the specific protein detection pool to realize specific protein detection of the samples. Since the specific protein concentration of the samples collected by the collection module is high, the detection results of the specific protein detection are inaccurate. SUMMARY

[0004] To solve the above problems, the present application provides a blood analyzer and a detection method thereof, which dilutes the blood sample through a routine blood test module, prevents the specific protein concentration of the blood sample from being too high, and improves the accuracy of specific protein detection.

[0005] One of the technical solutions adopted by the present application is to provide a blood analyzer, which comprises a sampling module, a routine blood test module and a specific protein detection module; wherein:

[0006] The sampling module is used to collect a blood sample and add the blood sample to the routine blood test module, and the routine blood test module is used to dilute the blood sample.

[0007] The sampling module adds the diluted blood sample to the specific protein detection module, and the specific protein detection module is used to perform specific protein detection on the diluted blood sample.

[0008] Another technical solution adopted by the present application is to provide a detection method applied to the above-mentioned blood analyzer, which comprises:

[0009] Collecting a blood sample and adding the blood sample to the routine blood test module;

[0010] Diluting the blood sample through the routine blood test module;

[0011] Adding the diluted blood sample to the specific protein detection module to perform specific protein detection on the diluted blood sample.

[0012] The blood analyzer of the application comprises a sampling module, a routine blood test module and a specific protein detection module, the sampling module is used for collecting a blood sample, the blood sample is added to the routine blood test module, the routine blood test module is used for diluting the blood sample; the sampling module adds the diluted blood sample to the specific protein detection module, the specific protein detection module is used for specific protein detection of the diluted blood sample; the blood sample is diluted by the routine blood test module to prevent the specific protein concentration of the blood sample from being too high, and the accuracy of the blood analyzer detection is improved. In addition, the first routine blood test pool of the routine blood test module performs routine blood test on the diluted blood sample, and the specific protein detection pool is used for specific protein detection of the diluted blood sample, so that the blood analyzer simultaneously realizes routine blood test and specific protein detection, improves the detection efficiency of the blood analyzer, and avoids the trouble caused by multiple sampling to the patient. BRIEF DESCRIPTION OF DRAWINGS

[0013] In order to more clearly illustrate the technical solutions in the embodiments of the application, the drawings needed to be used in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the application, and other drawings can be obtained by those skilled in the art without creative labor. Among them:

[0014] Figure 1 is a structural schematic diagram of the first embodiment of the blood analyzer of the application;

[0015] Figure 2 is a structural schematic diagram of the second embodiment of the blood analyzer of the application;

[0016] Figure 3 is a structural schematic diagram of the third embodiment of the blood analyzer of the application;

[0017] Figure 4 is a structural schematic diagram of the fourth embodiment of the blood analyzer of the application;

[0018] Figure 5 is a flowchart of the first embodiment of the detection method of the application;

[0019] Figure 6 is a flowchart of the second embodiment of the detection method of the application. DETAILED DESCRIPTION

[0020] With reference to the drawings, the technical solutions in the embodiments of the present application will be clearly and completely described below. It can be understood that the specific embodiments described here are only used to explain the present application, but not to limit the present application. In addition, it should be noted that, for the convenience of description, only the parts related to the present application are shown in the drawings, but not all the structures. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.

[0021] The terms "first", "second", and the like in the present application are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "include" and "have" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device including a series of steps or units is not limited to the listed steps or units, but optionally further includes steps or units not listed, or optionally further includes other steps or units inherent to the process, method, product or device.

[0022] In this document, the term "embodiment" means that the specific features, structures or characteristics described in connection with the embodiment can be included in at least one embodiment of the present application. The phrase appears at various places in the specification does not necessarily refer to the same embodiment, nor is it necessarily mutually exclusive or alternative embodiments. Those skilled in the art explicitly and implicitly understand that the embodiments described herein can be combined with other embodiments.

[0023] Please refer to Figure 1 shown, Figure 1 is a structural schematic diagram of a first embodiment of a blood analyzer of the present application. The blood analyzer 10 of the present embodiment at least includes a sampling module 11, a routine blood test module 12 and a specific protein detection module 13.

[0024] The sampling module 11 is used to collect a blood sample; when the blood analyzer 10 performs routine blood test through the routine blood test module 12 and specific protein detection through the specific protein detection module 13, the blood sample is a whole blood sample.

[0025] Among them, the routine blood test includes WBC (white blood cell), HGB (hemoglobin), RBC (red blood cell), DIFF (differential, white blood cell five classification) or RET (reticulocyte count).

[0026] The sampling module 11 is used to add the collected blood sample to the blood routine testing module 12. The blood routine testing module 12 is used to dilute the blood sample; that is, the blood routine testing module 12 serves as a dilution pool for the specific protein detection module 13 to dilute the blood sample. For example, the blood sample and the diluent in the blood routine testing module 12 are mixed to allow the blood routine testing module 12 to dilute the blood sample.

[0027] The sampling module 11 is used to draw diluted blood samples from the blood routine test module 12 and add the diluted blood samples to the specific protein detection module 13. The specific protein detection module 13 is used to perform specific protein detection on the diluted blood samples.

[0028] Among them, the specific proteins include one of SAA (serum amyloid A protein), CRP (C-reactive protein), TRF (transferrin), Hs-CRP (high-sensitivity C-reactive protein), PCT (procalcitonin), and D-Dimer. For example, the specific protein detection module 13 performs CRP detection on diluted blood samples.

[0029] In this embodiment, the sampling module 11 adds the collected blood sample to the blood routine detection module 12, which dilutes the blood sample. The sampling module 11 then adds the diluted blood sample to the specific protein detection module 13, which performs specific protein detection on the diluted blood sample. In other words, the blood routine detection module 12 acts as a dilution pool for the specific protein detection module 13 to dilute the blood sample, preventing excessively high concentrations of specific proteins and improving the accuracy of the blood analyzer 10. Furthermore, the blood analyzer 10 performs both blood routine and specific protein detection, improving its detection efficiency and avoiding the inconvenience caused to patients by multiple samplings.

[0030] Please see Figure 2 As shown, Figure 2 This is a schematic diagram of the structure of a second embodiment of the blood analyzer of this application. The blood analyzer 10 includes a control module 14 connected to a sampling module 11, a routine blood count (RBC) testing module 12, and a specific protein detection module 13, respectively. The RBC testing module 12 includes a first RBC testing pool 121, and the specific protein detection module 13 includes a specific protein detection pool 131. In other embodiments, the RBC testing module 12 includes multiple RBC testing pools, and the specific protein detection module 13 includes multiple specific protein detection pools 131.

[0031] The first blood routine test pool 121 is configured to dilute the blood sample to obtain a diluted blood sample, and further configured to perform blood routine test on the diluted blood sample. The specific protein test pool 131 is configured to perform specific protein test on the diluted blood sample, for example, the specific protein test pool 131 is configured to perform CRP test on the diluted blood sample.

[0032] The control module 14 is configured to control the sampling module 11 to draw the blood sample from the blood sample test tube 15, i.e., the control module 14 controls the sampling module 11 to draw the blood sample from the blood sample test tube 15 at the blood sampling position. For example, the blood analyzer 10 can include a test tube rack, and the plurality of blood sample test tubes 15 are arranged on the test tube rack. The test tube rack is configured to sequentially move the plurality of blood sample test tubes 15 to the blood sampling position, and the blood sampling position is the position where the sampling module 11 draws the blood sample.

[0033] Optionally, the blood analyzer 10 includes an optical coupling positioning assembly arranged at the blood sampling position and configured to determine whether the blood sample test tube 15 is located at the blood sampling position. For example, the control module 14 is configured to control the test tube rack to sequentially move the plurality of blood sample test tubes 15, and determine that the blood sample test tube 15 is located at the blood sampling position by the optical coupling positioning assembly, and then stop the test tube rack from sequentially moving the plurality of blood sample test tubes 15.

[0034] The control module 14 is configured to control the sampling module 11 to add the blood sample to the first blood routine test pool 121, so as to mix the blood sample and the diluent in the first blood routine test pool 121 to obtain a diluted blood sample. The first blood routine test pool 121 can store a certain amount of diluent. After the sampling module 11 adds the blood sample to the first blood routine test pool 121, the control module 14 can control the sampling module 11 to draw and push the blood sample and the diluent, so as to mix the blood sample and the diluent in the first blood routine test pool 121. In other embodiments, the bottom of the blood routine test pool (e.g., the first blood routine test pool 121) is provided with a mixing device, for example, a mixing device such as a pump or a syringe, to mix the liquid in the blood routine test pool.

[0035] The control module 14 is configured to control the sampling module 11 to perform cleaning and draw the diluted blood sample from the first blood routine test pool 121. In order to avoid contamination of the diluted blood sample in the first blood routine test pool 121, the sampling module 11 is cleaned. The control module 14 controls the sampling module 11 to draw the diluted blood sample from the first blood routine test pool 121.

[0036] The control module 14 is configured to control the sampling module 11 to add the diluted blood sample into the specific protein detection pool 131, so as to mix the diluted blood sample with the hemolytic agent and the latex reagent in the specific protein detection pool 131, and then perform specific protein detection on the diluted blood sample. For example, the blood analyzer 10 can comprise a reagent module, and the control module 14 controls the reagent module to add the hemolytic agent and the latex reagent (also referred to as antibody reagent) into the specific protein detection pool 131, so as to mix the diluted blood sample, the hemolytic agent and the latex reagent, and the control module 14 performs specific protein detection on the diluted blood sample through the specific protein detection pool 131.

[0037] In some embodiments, the control module 14 can control the sampling module 11 to aspirate and eject the diluted blood sample, the hemolytic agent and the latex reagent, so as to mix the diluted blood sample, the hemolytic agent and the latex reagent. In other embodiments, the specific protein detection pool 131 is provided with a mixing device at the bottom, such as a pumping device or a syringe, to mix the liquid in the specific protein detection pool 131.

[0038] Optionally, the control module 14 determines whether the specific protein detection pool 131 performs specific protein detection on the diluted blood sample abnormally. If so, the control module 14 determines that the specific protein detection pool 131 performs specific protein detection on the diluted blood sample abnormally, and then controls the sampling module 11 to re-aspirate the diluted blood sample from the first blood routine detection pool 121 and add the diluted blood sample into the specific protein detection pool 131, so as to re-perform specific protein detection on the diluted blood sample by the specific protein detection pool 131.

[0039] Optionally, the first blood routine detection pool 121 is arranged between the specific protein detection pool 131 and the blood sampling position, so that the sampling module 11 moves the shortest distance during the detection of the blood analyzer 10, thereby shortening the detection time of the blood analyzer 10 and improving the detection efficiency of the blood analyzer 10.

[0040] Optionally, before the sampling module 11 aspirates the blood sample from the blood sample tube 15, the control module 14 further controls the sampling module 11 to aspirate the blood sample from the blood sample tube 15 and add the blood sample into the specific protein detection pool 131, so as to perform specific protein detection on the blood sample and obtain a first detection result. The control module 14 determines whether the blood sample is a high-value sample based on the first detection result. If so, the control module 14 determines that the blood sample is a high-value sample, and then controls the sampling module 11 to aspirate the blood sample from the blood sample tube 15 to dilute the blood sample through the first blood routine detection pool 121. Therefore, the sampling module 11 realizes secondary sampling, and the high-value sample is diluted, thereby improving the accuracy of the detection of the blood analyzer 10.

[0041] Optionally, when the sampling module 11 completes the suction of the blood sample from the blood sample tube 15, the control module 14 controls the tube rack to continue the movement of the blood sample tube 15. When the control module 14 determines that the blood sample is a high-value sample, the control module 14 controls the tube rack to return the sampled blood sample tube 15 to the blood collection position. When the control module 14 determines that the blood sample is not a high-value sample, the blood sample tube 15 continues to move, which can improve the detection efficiency of the blood analyzer 10.

[0042] Please refer to Figure 3 as shown, Figure 3 is a structural schematic diagram of a third embodiment of the blood analyzer of the present application. The blood analyzer 10 of the present embodiment comprises a first container C1 for storing diluent, and the sampling module 11 comprises a driving device 111, a syringe 112, a controllable valve 113, and a sampling needle 114.

[0043] The driving device 111 is connected to the control module 14 and the syringe 112, respectively, and is used to drive the syringe 112. The common end of the controllable valve 113 is connected to the syringe 112 through a pipeline, the first branch end of the controllable valve 113 is connected to the first container C1 through a pipeline, and the second branch end of the controllable valve 113 is connected to the sampling needle 114 through a pipeline. In other embodiments, the sampling module 11 can be provided with a quantitative pump to realize the functions of the driving device 111 and the syringe 112.

[0044] The control module 14 controls the common end and the first branch end of the controllable valve 113 to be in communication, so that the syringe 112 sequentially communicates the controllable valve 113 and the first container C1 through the pipeline; the control module 14 controls the syringe 112 to suck the diluent from the first container C1 through the driving device 111. The control module 14 controls the common end and the second branch end of the controllable valve 113 to be in communication, so that the syringe 112 sequentially communicates the controllable valve 113 and the sampling needle 114 through the pipeline, and at this time the syringe 112 sucks or pushes out the blood sample and the diluted blood sample through the sampling needle 114.

[0045] The controllable valve 113 can be a three-way valve, which comprises a common end and two branch ends. The three-way valve realizes the selection of the three ports by means of on-off electricity, for example, when powered on, the common end and the first branch end are selected, and when powered off, the common end and the second branch end are selected. Those skilled in the art should know that if the connection mode of the first branch end and the second branch end is exchanged and the selection of the three-way valve is controlled in the opposite way, the same effect as the above-mentioned embodiment can be achieved, which should also be within the scope of the present embodiment.

[0046] Optionally, the sampling module 11 comprises a cleaning swab 115, which is arranged on the sampling needle 114 and is used to clean the outer wall and the inner wall of the sampling needle 114.

[0047] In addition, the sampling module 11 comprises a moving assembly, and the sampling needle 114 is arranged on the moving assembly. The moving assembly is configured to drive the sampling needle 114 to move in the horizontal direction or the vertical direction, so as to drive the sampling needle 114 to move.

[0048] The first blood routine detection pool 121 can comprise a WBC detection pool, an RBC detection pool, a DIFF detection pool or a RET detection pool. When the first blood routine detection pool 121 is the RBC detection pool, the control module 14 controls the sampling module 11 to add a diluent to the first blood routine detection pool 121, so as to perform RBC detection through the first blood routine detection pool 121 when performing specific protein detection on the diluted blood sample.

[0049] The detection process of the blood analyzer 10 is described in detail as follows:

[0050] The control module 14 controls the sampling needle 114 to move to the blood sampling position, so as to suck the blood sample from the blood sample tube 15 located at the blood sampling position. For example, the control module 14 controls the moving assembly to move the sampling needle 114 to the blood sampling position, where the blood sampling position is the initial position of the sampling needle 114.

[0051] The control module 14 controls the sampling needle 114 to move to the first blood routine detection pool 121, and adds the blood sample to the first blood routine detection pool 121. The blood sample is mixed with the diluent in the first blood routine detection pool 121, so as to obtain the diluted blood sample.

[0052] The control module 14 controls the sampling needle 114 to move, and the outer wall and the inner wall of the sampling needle 114 are cleaned by the cleaning swab 115, so as to prevent the blood sample remaining in the sampling needle 114 from contaminating the diluted blood sample.

[0053] The control module 14 controls the sampling needle 114 to move to the first blood routine detection pool 121, so as to suck the diluted blood sample from the first blood routine detection pool 121. The control module 14 controls the sampling needle 114 to move to the specific protein detection pool 131, so as to add the diluted blood sample to the specific protein detection pool 131.

[0054] The diluted blood sample, the hemolytic agent and the latex reagent in the specific protein detection pool 131 are mixed, so as to perform specific protein detection on the diluted blood sample. Meanwhile, the control module 14 controls the sampling needle 114 to move to the first blood routine detection pool 121, so as to add the diluent to the first blood routine detection pool 121. Then, the diluted blood sample is diluted and mixed again, so as to detect the RBC signal and perform RBC detection.

[0055] The control module 14 controls the sampling needle 114 to move, and the outer wall and the inner wall of the sampling needle 114 are cleaned by the cleaning swab 115.

[0056] The RBC detection pool of the embodiment serves as a dilution pool of the specific protein detection module 13 to dilute the blood sample to prevent the specific protein concentration of the blood sample from being too high and improve the accuracy of the blood analyzer 10. In addition, the RBC detection pool is used to detect the RBC of the diluted blood sample, so that the RBC detection and the specific protein detection are realized at the same time, the detection efficiency of the blood analyzer 10 is improved, and the patient is also avoided from being disturbed by multiple sampling.

[0057] Please refer to Figure 4 , Figure 4 is a structural schematic diagram of the fourth embodiment of the blood analyzer of the application. The blood routine detection module 12 of the embodiment further includes a second blood routine detection pool 122.

[0058] The control module 14 is configured to control the sampling module 11 to suck the blood sample from the blood sample test tube 15. The control module 14 is configured to control the sampling module 11 to add the blood sample into the first blood routine detection pool 121 to mix the blood sample and the diluent in the first blood routine detection pool 121 to obtain the diluted blood sample.

[0059] The control module 14 is configured to control the sampling module 11 to perform cleaning and suck the diluted blood sample from the first blood routine detection pool 121. The control module 14 is configured to control the sampling module 11 to add the diluted blood sample into the specific protein detection pool 131 to mix the diluted blood sample with the hemolytic agent and the latex reagent of the specific protein detection pool 131, and then perform specific protein detection on the diluted blood sample.

[0060] The control module 14 is configured to control the sampling module 11 to add the diluted blood sample into the second blood routine detection pool 122 to perform blood routine detection through the first blood routine detection pool 121 and the second blood routine detection pool 122 at the same time. In the process of adding the diluted blood sample into the second blood routine detection pool 122 by the sampling module 11, the diluted blood sample is mixed with the diluent in the second blood routine detection pool 122 to perform blood routine detection through the second blood routine detection pool 122.

[0061] The first blood routine detection pool 121 of the embodiment is a WBC detection pool, and the second blood routine detection pool 122 is an RBC detection pool. The detection process of the blood analyzer 10 is described in detail as follows:

[0062] The control module 14 controls the sampling needle 114 to move to the blood sampling position to suck the blood sample from the blood sample test tube 15 located at the blood sampling position.

[0063] The control module 14 controls the sampling needle 114 to move to the first blood routine test pool 121, and the blood sample is added to the first blood routine test pool 121; wherein the blood sample and the diluent in the first blood routine test pool 121 are mixed to obtain the diluted blood sample.

[0064] The control module 14 controls the sampling needle 114 to move, and the outer wall and the inner wall of the sampling needle 114 are cleaned by the cleaning swab 115, so as to prevent the blood sample remaining in the sampling needle 114 from contaminating the diluted blood sample.

[0065] The control module 14 controls the sampling needle 114 to move to the first blood routine test pool 121 to suck the diluted blood sample from the first blood routine test pool 121; and controls the sampling needle 114 to move to the specific protein test pool 131 to add the diluted blood sample to the specific protein test pool 131.

[0066] The diluted blood sample, the hemolytic agent and the latex reagent in the specific protein test pool 131 are mixed to perform specific protein detection on the diluted blood sample.

[0067] The control module 14 controls the sampling needle 114 to move to the first blood routine test pool 121 to suck the diluted blood sample from the first blood routine test pool 121.

[0068] The control module 14 controls the sampling needle 114 to move to the second blood routine test pool 122 to add the diluted blood sample to the second blood routine test pool 122, and then the diluted blood sample and the diluent in the second blood routine test pool 122 are mixed to detect the RBC signal and realize RBC detection. Meanwhile, the control module 14 controls the reagent module to add the hemolytic agent to the first blood routine test pool 121, and the diluted blood sample and the hemolytic agent are mixed to detect the WBC signal and realize WBC detection.

[0069] The control module 14 controls the sampling needle 114 to move, and the outer wall and the inner wall of the sampling needle 114 are cleaned by the cleaning swab 115.

[0070] The WBC detection pool in the embodiment serves as the dilution pool of the specific protein detection module 13 to dilute the blood sample, so as to prevent the specific protein concentration of the blood sample from being too high and improve the detection accuracy of the blood analyzer 10. In addition, the diluted blood sample is added to the RBC detection pool to mix the diluted blood sample and the diluent in the RBC detection pool, so that the diluent does not need to be added to the RBC detection pool, and the detection efficiency is improved. Furthermore, the WBC detection, the RBC detection and the specific protein detection are realized, the detection efficiency of the blood analyzer 10 is improved, and the patient is also avoided from being disturbed by multiple sampling.

[0071] Please refer to Figure 5 as shown, Figure 5is a flowchart of a detection method first embodiment of the present application. The detection method of the present embodiment is applied to the blood analyzer 10 disclosed in the above embodiments, and the detection method comprises the following steps:

[0072] S501: Collecting a blood sample and adding the blood sample to the routine blood test module 12.

[0073] The blood sample is collected by the sampling module 11 and added to the routine blood test module 12.

[0074] S502: Diluting the blood sample by the routine blood test module 12.

[0075] The routine blood test module 12 serves as a dilution pool for the specific protein detection module 13 to dilute the blood sample. For example, the blood sample and the diluent in the routine blood test module 12 are mixed to dilute the blood sample by the routine blood test module 12.

[0076] S503: Adding the diluted blood sample to the specific protein detection module 13 to detect specific proteins in the diluted blood sample.

[0077] The diluted blood sample is collected by the sampling module 11 and added to the specific protein detection module 13 to detect specific proteins in the diluted blood sample.

[0078] The step S501 comprises: controlling the sampling module 11 to draw the blood sample from the blood sample test tube 15 and add the blood sample to the first routine blood test pool 121. That is, the control module 14 controls the sampling module 11 to draw the blood sample from the blood sample test tube 15 and add the blood sample to the first routine blood test pool 121.

[0079] The step S502 comprises: mixing the blood sample and the diluent in the first routine blood test pool 121 by the first routine blood test pool 121 to obtain the diluted blood sample.

[0080] The step S503 comprises: controlling the sampling module 11 to be cleaned and draw the diluted blood sample from the first routine blood test pool 121; controlling the sampling module 11 to add the diluted blood sample to the specific protein detection pool 131 so that the diluted blood sample is mixed with the hemolytic agent and the latex reagent of the specific protein detection pool 131, and then the specific protein detection is performed on the diluted blood sample.

[0081] The control module 14 controls the sampling module 11 to perform cleaning and to suck the diluted blood sample from the first blood routine test pool 121. The control module 14 controls the sampling module 11 to add the diluted blood sample into the specific protein test pool 131, so that the diluted blood sample is mixed with the hemolytic agent and the latex reagent of the specific protein test pool 131, and then the specific protein test is performed on the diluted blood sample.

[0082] In this embodiment, the blood sample collected by the sampling module 11 is added into the blood routine test module 12, and the blood sample is diluted by the blood routine test module 12, i.e., the blood routine test module 12 serves as a dilution pool of the specific protein test module 13, so as to dilute the blood sample to prevent the specific protein concentration of the blood sample from being too high and improve the accuracy of the blood analyzer 10. In addition, the blood routine test and the specific protein test are realized, the detection efficiency of the blood analyzer 10 is improved, and the patient is not disturbed by multiple samplings.

[0083] Please refer to Figure 6 , and Figure 6 is a flowchart of the detection method of the second embodiment of the application. The detection method of this embodiment includes the following steps:

[0084] S601: Collect a blood sample, and add the blood sample into the specific protein test module 13 to perform specific protein test on the blood sample.

[0085] The blood sample is collected by the sampling module 11. The blood sample is added into the specific protein test module 13 by the sampling module 11 to perform specific protein test on the blood sample, and the first detection result is obtained.

[0086] S602: If it is determined that the blood sample is a high-value sample, then the step of collecting the blood sample is entered.

[0087] It is determined whether the blood sample is a high-value sample based on the first detection result. The high-value sample refers to a blood sample with a specific protein concentration greater than a certain threshold. If yes, it is determined that the blood sample is a high-value sample, and the step S603 is entered. If no, the next blood sample is detected by the blood analyzer 10.

[0088] S603: Collect a blood sample, and add the blood sample into the blood routine test module 12.

[0089] S604: Dilute the blood sample by the blood routine test module 12.

[0090] S605: Add the diluted blood sample into the specific protein test module 13 to perform specific protein test on the diluted blood sample.

[0091] Steps S603-S605 are the same as steps S501-S503 in the detection method of the first embodiment, and will not be described again here.

[0092] In the first blood routine detection pool 121 is an RBC detection pool, the detection method further comprises: when detecting the specific protein of the diluted blood sample, the sampling module 11 is controlled to add a diluent to the first blood routine detection pool 121, so as to perform RBC detection through the first blood routine detection pool 121. The control module 14 controls the sampling module 11 to add a diluent to the first blood routine detection pool 121, so as to perform RBC detection through the first blood routine detection pool 121.

[0093] Alternatively, the blood routine detection module 12 comprises a second blood routine detection pool 122, and the detection method further comprises: the sampling module 11 is controlled to add the diluted blood sample to the second blood routine detection pool 122, so as to perform blood routine detection through the first blood routine detection pool 121 and the second blood routine detection pool 122 simultaneously.

[0094] The control module 14 controls the sampling module 11 to add the diluted blood sample to the second blood routine detection pool 122, so as to perform blood routine detection through the first blood routine detection pool 121 and the second blood routine detection pool 122 simultaneously. Wherein, after the sampling module 11 adds the diluted blood sample to the second blood routine detection pool 122, the diluted blood sample and the diluent in the second blood routine detection pool 122 are mixed evenly, so as to perform blood routine detection through the second blood routine detection pool 122.

[0095] The embodiment improves the accuracy of the blood analyzer 10 by collecting blood samples twice to dilute the high-value sample through the blood routine detection module 12.

[0096] In summary, the blood routine detection module 12 of the present application serves as a dilution pool of the specific protein detection module 13 to dilute the blood sample, so as to prevent the specific protein concentration of the blood sample from being too high, and improve the accuracy of the blood analyzer 10. In addition, the blood analyzer 10 simultaneously realizes blood routine detection and specific protein detection, improves the detection efficiency of the blood analyzer 10, and also avoids the trouble caused to the patient by multiple sampling.

[0097] In the several embodiments provided in the present application, it should be understood that the disclosed device can be implemented in other ways. For example, the device embodiments described above are only schematic. The division of the modules or units is only a logical function division. There can be another division manner in actual implementation. For example, a plurality of units or components can be combined or integrated into another system, or some features can be ignored or not executed.

[0098] The units described as separate components may or may not be physically separate, and the components displayed as units may or may not be physical units, that is, may be located in one place, or may be distributed to multiple network units. Part or all of the units can be selected according to actual needs to achieve the purpose of the present embodiment scheme.

[0099] In addition, each functional unit in each embodiment of the present application can be integrated into one processing unit, or each unit can exist physically alone, or two or more units can be integrated into one unit. The integrated unit can be realized in the form of hardware or in the form of a software functional unit.

[0100] The above is only an embodiment of the present application, and does not limit the patent scope of the present application, and any equivalent structure or equivalent process transformation according to the content of the specification and drawings of the present application, or direct or indirect application in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A blood analyzer characterized by, The blood analyzer comprises a sampling module, a routine blood test module, a specific protein test module, and a control module connected with the sampling module, the routine blood test module and the specific protein test module respectively; wherein: The control module controls the sampling module to suck the blood sample from the blood sample test tube and add the blood sample into the specific protein test module to perform specific protein test on the blood sample to obtain a first test result; If the control module determines that the blood sample is a high-value sample based on the first test result, the sampling module is used to collect the blood sample and add the blood sample into the routine blood test module, and the routine blood test module is used to dilute the blood sample. The sampling module adds the diluted blood sample into the specific protein test module, and the specific protein test module is used to perform specific protein test on the diluted blood sample. When the sampling module completes sucking the blood sample from the blood sample test tube, the control module controls a test tube rack to move the blood sample test tube; when the control module determines that the blood sample is a high-value sample, the control module controls the test tube rack to return the sampled blood test tube to a blood sampling position.

2. The blood analyzer of claim 1, wherein, The routine blood test module comprises a first routine blood test pool, which is used to dilute the blood sample and perform routine blood test on the diluted blood sample; The specific protein test module comprises a specific protein test pool, which is used to perform specific protein test on the diluted blood sample.

3. The blood analyzer of claim 2, wherein, The control module is used to: control the sampling module to suck the blood sample from the blood sample test tube; control the sampling module to add the blood sample into the first routine blood test pool to mix the blood sample and diluent in the first routine blood test pool to obtain the diluted blood sample; control the sampling module to perform cleaning and suck the diluted blood sample from the first routine blood test pool; control the sampling module to add the diluted blood sample into the specific protein test pool to mix the diluted blood sample with hemolytic agent and latex reagent in the specific protein test pool, and then perform specific protein test on the diluted blood sample.

4. The blood analyzer of claim 3, wherein, The routine blood test module comprises a second routine blood test pool, and the control module is used to control the sampling module to add the diluted blood sample into the second routine blood test pool to perform routine blood test through the first routine blood test pool and the second routine blood test pool simultaneously.

5. The blood analyzer of claim 3, wherein, The first routine blood test pool is an RBC test pool, and when performing specific protein test on the diluted blood sample, the control module controls the sampling module to add diluent into the first routine blood test pool to perform RBC test through the first routine blood test pool.

6. The blood analyzer according to any one of claims 2-4, wherein, The first routine blood test pool comprises a WBC / HGB test pool, an RBC test pool, a DIFF test pool or a RET test pool; The specific protein includes one of SAA, CRP, TRF, Hs-CRP, PCT and D-Dimer.

7. A method of detection, characterized in that The detection method is applied to the blood analyzer of any one of claims 1-6, and the detection method comprises: collecting a blood sample; adding the blood sample to the specific protein detection module to detect specific proteins in the blood sample; when it is determined that the blood sample is a high-value sample, collecting the blood sample and adding the blood sample to the blood routine detection module; diluting the blood sample by the blood routine detection module; adding the diluted blood sample to the specific protein detection module to detect specific proteins in the diluted blood sample; wherein, when the sampling module completes the blood sample from the blood sample test tube, the control module controls the test tube rack to move the blood sample test tube; when the control module determines that the blood sample is a high-value sample, the control module controls the test tube rack to return the sampled blood test tube to the blood collection position.

8. The detection method according to claim 7, characterized in that, The blood routine detection module comprises a first blood routine detection pool, and the specific protein detection module comprises a specific protein detection pool, and the step of collecting a blood sample and adding the blood sample to the blood routine detection module comprises: controlling the sampling module to suck the blood sample from the blood sample test tube and add the blood sample to the first blood routine detection pool; The step of diluting the blood sample by the blood routine detection module comprises: mixing the blood sample and the diluent in the first blood routine detection pool to obtain the diluted blood sample; The step of adding the diluted blood sample to the specific protein detection module to detect specific proteins in the diluted blood sample comprises: controlling the sampling module to clean and suck the diluted blood sample from the first blood routine detection pool; controlling the sampling module to add the diluted blood sample to the specific protein detection pool to mix the diluted blood sample with the hemolytic agent and the latex reagent in the specific protein detection pool, and then to detect specific proteins in the diluted blood sample.

9. The detection method according to claim 8, characterized in that, The first blood routine detection pool is an RBC detection pool, and the detection method further comprises: when detecting specific proteins in the diluted blood sample, controlling the sampling module to add a diluent to the first blood routine detection pool to perform RBC detection by the first blood routine detection pool.

10. The detection method of claim 8, wherein, The blood routine detection module comprises a second blood routine detection pool, and the detection method further comprises: controlling the sampling module to add the diluted blood sample to the second blood routine detection pool to simultaneously perform blood routine detection by the first blood routine detection pool and the second blood routine detection pool.

Citation Information

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