Aneurysm Interventional Embolization Delivery Device

Abstract

The present invention discloses an interventional embolization delivery device for aneurysms, which includes a microcatheter, a guide wire, and a radiopaque marker ring. The microcatheter is sleeved outside the guide wire, and the distal end of the guide wire is provided with a radiopaque marker ring. It also includes a distal fixing protrusion, a proximal fixing protrusion, and a limiting protrusion. The distal end of the guide wire is provided with a distal fixing protrusion that cooperates with the distal connection hole of the filler and a proximal fixing protrusion that cooperates with the proximal connection hole of the filler. The distal fixing protrusion and the proximal fixing protrusion are arranged in sequence along the axial direction of the guide wire. A limiting protrusion that cooperates with the filler spirally wound around the distal end of the guide wire is provided on the guide wire between the distal fixing protrusion and the proximal fixing protrusion. The limiting protrusion, the distal fixing protrusion, and the proximal fixing protrusion are in clearance fit with the microcatheter. The present invention has the advantages of simple structure, capable of realizing spiral winding of the filler, not easily displaced, and convenient for release.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to an aneurysm interventional embolization delivery device. Background Art

[0002] Aneurysms are common vascular diseases. They are caused by lesions or damage to the arterial wall, resulting in localized or diffuse expansion or bulging of the arterial wall. They are mainly manifested as expansive, pulsating masses and can occur in any part of the arterial system. One of the treatment options for aneurysms is vascular interventional therapy, in which a microcatheter is inserted from the femoral artery into the aneurysm through a guide catheter. Fillers are placed into the aneurysm cavity through the microcatheter and guidewire. The blood flow pattern in the aneurysm is significantly reduced, leading to thrombosis (coagulation) of the aneurysm. The thrombosed aneurysm will resist the entry of liquid blood, achieving the purpose of treatment.

[0003] The commonly used fillers for vascular interventional treatment on the market currently use spring coils, but they are not suitable for all hemangiomas. Intravascular fillers that can replace spring coils are gradually emerging, opening up more options for the treatment of aneurysms. CN2017800452528 is a system and method for embolic occlusion of neurovascular aneurysms, which discloses the structures and implementation methods of various fillers. Figures 14A to 14D of the specification disclose an implementation method of one of the fillers, which is composed of one or more segments connected end to end. One or more segments can be configured so that the segments are arranged at a certain angle relative to adjacent segments. A proximal connecting hole is provided at the proximal end of the filler, a distal connecting hole is provided at the distal end, and a transition connecting hole is provided at the transition between adjacent segments. The connecting holes are provided for auxiliary connection with a delivered support line or other structure, but there is no good solution for how to deliver the filler of this structure and how to release it from the catheter and enter the aneurysm. Summary of the invention

[0004] The purpose of the present invention is to solve the above-mentioned deficiencies of the prior art and to provide an aneurysm interventional embolization delivery device which has a simple structure, can realize spiral winding of fillers, is not easy to shift, and is easy to release.

[0005] The technical solution adopted by the present invention to solve its technical problem is:

[0006] An aneurysm interventional embolization delivery device comprises a microcatheter, a guide wire, and a development marker ring, wherein the microcatheter is sleeved outside the guide wire, and the distal end of the guide wire is provided with a development marker ring, characterized in that: it also comprises a distal fixing protrusion, a proximal fixing protrusion, and a limiting protrusion, and the distal end of the guide wire is provided with a distal fixing protrusion matched with a distal connection hole of a filler, and a proximal fixing protrusion matched with a proximal connection hole of the filler, and the distal fixing protrusion and the proximal fixing protrusion are sequentially arranged along the axial direction of the guide wire, and the distal fixing protrusion and the proximal fixing protrusion on the guide wire are provided with a distal fixing protrusion and a limiting protrusion. A limiting protrusion is provided between the proximal fixing protrusions to cooperate with the filler spirally wound on the distal end of the guide wire. The limiting protrusion, the distal fixing protrusion, the proximal fixing protrusion and the microcatheter gap cooperate. The filler is spirally wound on the guide wire, and the adjacent spiral segments are limited by the limiting protrusion. The connecting holes at both ends of the filler are respectively mounted on the distal fixing protrusion and the proximal fixing protrusion to ensure that the filler can be limited at the distal end of the guide wire. The filler will not shift when the guide wire is pushed in the microcatheter. At the same time, when the guide wire reaches the aneurysm, the filler is easy to release.

[0007] The limiting protrusions of the present invention are unit discontinuous protrusions arranged at intervals along the axial direction of the guide wire, and the adjacent spiral sections of the filler are separated by arranging the unit discontinuous protrusions.

[0008] The limiting protrusion of the present invention is a spiral protrusion extending along the axial direction of the guide wire. The spiral protrusion is arranged to cooperate with the spirally wound filler to separate adjacent spiral sections of the filler.

[0009] The gap size between the limiting protrusion and the inner wall of the microcatheter is smaller than the plane thickness of the filler, ensuring that the filler will not be released prematurely. At the same time, it also plays a role in limiting the filler and preventing the spiral filler from passing through the gap between the limiting protrusion and the inner wall of the microcatheter.

[0010] The height of the limiting protrusion along the radial direction of the guidewire is greater than the plane thickness of the filler, ensuring that the limiting protrusion rubs against the inner wall of the microcatheter during the pushing process of the guidewire, and the filler does not contact the inner wall of the microcatheter.

[0011] The angle between the radial surface of the limiting protrusion and the guide wire axis is less than or equal to 90 degrees to prevent the filler from moving along the outer surface of the unit limiting protrusion.

[0012] The unit discontinuous protrusions of the present invention are in the shape of long strips and extend in a spiral shape relative to the axial direction of the guide wire, so as to cooperate with the filler spirally wound on the distal end of the guide wire, thereby further ensuring a good limiting effect.

[0013] The unit discontinuous protrusions described in the present invention are point-shaped protrusions, which are used to limit the filler spirally wound on the distal end of the guide wire.

[0014] The development marker ring of the present invention is arranged on the guide wire near the distal fixing protrusion and / or the proximal fixing protrusion.

[0015] The beneficial effects of the present invention are as follows: the filler is spirally wound on the guide wire, and adjacent spiral segments are limited by limiting protrusions. The connecting holes at both ends of the filler are respectively sleeved on the distal fixing protrusion and the proximal fixing protrusion, ensuring that the filler can be limited at the distal end of the guide wire, and the filler will not shift when the guide wire is pushed in the microcatheter. At the same time, when the guide wire reaches the aneurysm, the filler is easy to release; the gap size between the limiting protrusion and the inner wall of the microcatheter is smaller than the thickness of the filler, ensuring that the filler will not be released prematurely, and also plays a role in limiting the filler, preventing the spiral filler from passing through the gap between the limiting protrusion and the inner wall of the microcatheter; the height of the limiting protrusion is greater than the thickness of the filler, ensuring that the limiting protrusion rubs against the inner wall of the microcatheter during the pushing process of the guide wire, and the filler does not contact the inner wall of the microcatheter. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a structural schematic diagram of the present invention in which limiting protrusions are arranged at intervals on the guide wire.

[0017] Figure 2 yes Figure 1 A cross-sectional view taken along the axial direction of the guide wire.

[0018] Figure 3 yes Figure 2 Enlarged schematic diagram at point A in the middle.

[0019] Figure 4 It is a structural schematic diagram of a spiral limiting protrusion provided on the guide wire of the present invention.

[0020] Figure 5 yes Figure 4 A cross-sectional view taken along the axial direction of the guide wire.

[0021] Figure 6 yes Figure 5 Enlarged schematic diagram of point B in the middle.

[0022] Figure 7 It is a schematic structural diagram of the cooperation between the upper limit projection of the guide wire and the filler of the present invention.

[0023] Figure 8 This is a schematic diagram of the planar structure of the filler of the present invention.

[0024] Figure numerals: guide wire-1, limiting protrusion-2, filler-3, connecting hole-301, distal fixing protrusion-4, proximal fixing protrusion-5. DETAILED DESCRIPTION

[0025] The present invention is described below in conjunction with the accompanying drawings and embodiments.

[0026] As shown in the accompanying drawings, an aneurysm interventional embolization delivery device includes a microcatheter, a guide wire 1, and a development marker ring (not shown in the figure). The microcatheter is sleeved outside the guide wire 1, and the distal end of the guide wire 1 is provided with a development marker ring, and also includes a distal fixing protrusion 4, a proximal fixing protrusion 5, and a limiting protrusion 2. The distal end of the guide wire 1 is provided with a distal fixing protrusion 4 that matches the connecting hole 301 at the distal end of the filler 3, and a proximal fixing protrusion 5 that matches the connecting hole 301 at the proximal end of the filler 3. The distal fixing protrusion 4 and the proximal fixing protrusion 5 are sequentially arranged along the axial direction of the guide wire 1. The guide wire 1 is provided with a distal fixing protrusion 4 that matches the connecting hole 301 at the distal end of the filler 3, and a proximal fixing protrusion 5 that matches the connecting hole 301 at the proximal end of the filler 3. The distal fixing protrusion 4 and the proximal fixing protrusion 5 are sequentially arranged along the axial direction of the guide wire 1. A limiting protrusion 2 is provided between the fixing protrusion 4 and the proximal fixing protrusion 5, which cooperates with the filler 3 spirally wound on the distal end of the guide wire. The limiting protrusion 2, the distal fixing protrusion 4, the proximal fixing protrusion 5 and the microcatheter gap cooperate. The filler 3 is spirally wound on the guide wire 1, and the adjacent spiral segments are limited by the limiting protrusion 2. The connecting holes 301 at both ends of the filler are respectively mounted on the distal fixing protrusion 4 and the proximal fixing protrusion 5, ensuring that the filler 3 can be limited at the distal end of the guide wire 1. The filler will not shift when the guide wire 1 is pushed in the microcatheter. At the same time, when the guide wire 1 reaches the aneurysm, the filler 3 is easy to release.

[0027] The limiting protrusions 2 are unit discontinuous protrusions arranged at intervals along the axial direction of the guide wire 1, and the adjacent spiral sections of the filler are separated by the unit discontinuous protrusions.

[0028] The limiting protrusion 2 is a spiral protrusion extending axially along the guide wire 1. The spiral protrusion is arranged to cooperate with the spirally wound filler to separate adjacent spiral segments of the filler.

[0029] The gap size between the limiting protrusion 2 and the inner wall of the microcatheter is smaller than the plane thickness of the filler 3, ensuring that the filler 3 will not be released prematurely. At the same time, it also plays a role in limiting the filler 3 and preventing the spiral filler from passing through the gap between the limiting protrusion 2 and the inner wall of the microcatheter.

[0030] The height of the limiting protrusion 2 along the radial direction of the guidewire 1 is greater than the plane thickness of the filler 3, ensuring that the limiting protrusion 2 rubs against the inner wall of the microcatheter during the pushing process of the guidewire 1, and the filler 3 does not contact the inner wall of the microcatheter.

[0031] The angle between the radial surface of the limiting protrusion 2 and the guidewire axis is less than or equal to 90 degrees to prevent the filler from moving along the outer surface of the unit limiting protrusion. In this embodiment, the connection between the radial surface of the limiting protrusion and the outer surface of the guidewire is the outer contour connection surface, and the angle between the outer contour connection surface and the guidewire axis is represented by θ. Figure 3 and Figure 6 It can be seen that the angle θ is less than or equal to 90 degrees, so that the filler will not move along the outer contour connecting surface of the limiting protrusion to the gap between the limiting protrusion and the microcatheter during the guide wire pushing process.

[0032] The unit discontinuous protrusion is in the shape of an elongated strip and extends in a spiral shape relative to the axial direction of the guide wire 1, so as to cooperate with the filler 3 spirally wound on the distal end of the guide wire 1, thereby further ensuring a good limiting effect.

[0033] The unit discontinuous protrusions are point-shaped protrusions, which are used to limit the filler spirally wound on the distal end of the guide wire.

[0034] The developing marker ring is arranged on the guide wire near the distal fixing protrusion 4 and / or the proximal fixing protrusion 5. In this embodiment, the developing marker ring is arranged at both the distal fixing protrusion 4 and the proximal fixing protrusion 5.

[0035] The filler shown in this embodiment is composed of multiple segments connected end to end, including a mesh structure with uniform pores and a non-porosity reinforcement part to provide smooth edges and structural support. Since the reinforcement part cannot be folded, it is transported in a spiral winding manner.

[0036] When the present invention is in use, the filler 3 is spirally wound around the distal end of the guide wire 1, and the adjacent spiral segments of the filler 3 are separated by the limiting protrusion 2. The connecting hole 301 at the distal end of the filler 3 is sleeved on the distal fixing protrusion 4, and the connecting hole 301 at the proximal end is sleeved on the proximal fixing protrusion 5. The guide wire 1 is arranged in the microcatheter, and the microcatheter is inserted from the femoral artery to the aneurysm through the guide catheter. The length of the microcatheter extending into the aneurysm is required to enable the spiral filler to be fully extended into the aneurysm, ensuring that the spiral filler can be released in the aneurysm. The guide wire 1 is pushed in the microcatheter to reach the aneurysm, and the microcatheter is withdrawn from the aneurysm, and the filler is detached from the distal fixing protrusion 4 and the proximal fixing protrusion 5 and released. In this embodiment, the filler 3 adopts a memory alloy, and the three-dimensional configuration after release is spherical. At this time, the guide wire is withdrawn from the aneurysm, and the blood flow pattern in the aneurysm is significantly reduced, resulting in thrombosis (coagulation) of the aneurysm. The thrombosed aneurysm will resist the entry of liquid blood, thereby achieving the purpose of treatment.

Claims

1. An interventional embolization delivery device for aneurysms, comprising a microcatheter, a guide wire, and a radiopaque marker ring. The microcatheter is sleeved outside the guide wire, and the distal end of the guide wire is provided with a radiopaque marker ring. Characterized in that: It further includes a distal fixing protrusion, a proximal fixing protrusion, and a limiting protrusion. The distal end of the guide wire is provided with a distal fixing protrusion that cooperates with the distal connection hole of the filler and a proximal fixing protrusion that cooperates with the proximal connection hole of the filler. The distal fixing protrusion and the proximal fixing protrusion are arranged in sequence along the axial direction of the guide wire. A limiting protrusion that cooperates with the filler spirally wound around the distal end of the guide wire is provided between the distal fixing protrusion and the proximal fixing protrusion on the guide wire. The limiting protrusion, the distal fixing protrusion, and the proximal fixing protrusion are in clearance fit with the microcatheter.

2. An interventional embolization delivery device for aneurysms according to claim 1, Characterized in that: The limiting protrusion is a unit intermittent protrusion arranged at intervals along the axial direction of the guide wire.

3. An interventional embolization delivery device for aneurysms according to claim 1, Characterized in that: The limiting protrusion is a spiral protrusion extending along the axial direction of the guide wire.

4. An interventional embolization delivery device for aneurysms according to claim 1 or 2 or 3, Characterized in that: The clearance size between the limiting protrusion and the inner wall of the microcatheter is smaller than the planar thickness of the filler.

5. An interventional embolization delivery device for aneurysms according to claim 4, Characterized in that: The height of the limiting protrusion in the radial direction of the guide wire is greater than the planar thickness of the filler.

6. An interventional embolization delivery device for aneurysms according to claim 1 or 2 or 3 or 5, Characterized in that: The included angle between the radial surface of the limiting protrusion and the axis of the guide wire is less than or equal to 90 degrees.

7. An interventional embolization delivery device for aneurysms according to claim 2, Characterized in that: The unit intermittent protrusion is long strip-shaped and extends spirally with respect to the axial direction of the guide wire.

8. An interventional embolization delivery device for aneurysms according to claim 2, Characterized in that: The unit intermittent protrusion is a dot-shaped protrusion.

9. An interventional embolization delivery device for aneurysms according to claim 1 or 2 or 3 or 5 or 7 or 8, Characterized in that: The radiopaque marker ring is arranged on the guide wire near the distal fixing protrusion and / or the proximal fixing protrusion.

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