Electronic capsule pressure sensor secondary calibration device and method

Abstract

The application provides a kind of electronic capsule pressure sensor secondary calibration device and method, including shell, control circuit, battery pack, pressure calibration module, air hole, data communication interface, storage module, system status indicator light, button etc.The application is based on electronic capsule before use pressure detection data and simultaneously recorded secondary calibration device pressure detection data, through algorithm correction, can effectively improve the precision of electronic capsule pressure detection, full automatic calibration, convenient and efficient.

Description

Technical Field

[0001] This invention relates to the technical field of medical devices, and more specifically, to a secondary calibration device and method for electronic capsule pressure sensors. Background Technology

[0002] The pressure sensor integrated into the electronic capsule is used to detect the pressure inside the digestive tract. By analyzing the collected pressure data, the gastrointestinal motility function can be assessed. Diffused silicon pressure sensors have advantages such as high sensitivity, good linearity, small size, and light weight, and are often integrated inside electronic capsules. Due to the limited internal space of the electronic capsule, a secondary packaging design using a bare diffused silicon pressure sensor die is typically employed to meet the overall design requirements of the electronic capsule.

[0003] Residual stress is introduced during the secondary packaging process, which can affect the long-term stability of the pressure sensor. The long-term stability of a secondary-packaged pressure sensor is a crucial technical indicator, as it impacts the validity and accuracy of the detection data.

[0004] A method for achieving long-term stable performance of an in vivo pressure sensor is disclosed in patent document CN114323403A. A layer of parylene material is deposited on a PDMS film by chemical vapor deposition. Due to the presence of the parylene deposition layer, the interfacial fluid and biological tissue fluid inside the pressure chamber are prevented from permeating each other, ensuring the stability of the chemical composition and interfacial fluid volume inside the pressure chamber. This method is then applied to the encapsulation of an in vivo pressure sensor.

[0005] Existing electronic capsule systems only calibrate the pressure sensor once before assembly is complete. As residual stress is released naturally, the pressure sensor in the electronic capsule will have certain measurement errors during use, reducing the feasibility of data acquisition.

[0006] Therefore, a new technical solution is needed to improve the above-mentioned technical problems. Summary of the Invention

[0007] To address the shortcomings of existing technologies, the purpose of this invention is to provide a secondary calibration device and method for an electronic capsule pressure sensor.

[0008] The present invention provides a secondary calibration device for an electronic capsule pressure sensor, comprising a control circuit, a battery pack, a storage module, a pressure calibration module, an air vent, a data communication interface, and a housing;

[0009] The housing contains a control circuit, a battery pack, a pressure calibration module, an air vent, a data communication interface, and a storage module. The battery pack is connected to the control circuit. The pressure calibration module is also connected to the control circuit. The air vent is located on the housing. The storage module receives pressure data detected by the electronic capsule and stores calibration parameters of the pressure calibration module and the integrated pressure sensor of the electronic capsule. The data communication interface records the latest calibration parameters in the storage module.

[0010] Preferably, the surface of the housing is provided with a system status indicator light and a button; the system status indicator light and the button are connected to the control circuit via a data cable.

[0011] Preferably, the pressure detected by the pressure calibration module is transmitted to the control circuit via a data bus and stored in the storage module.

[0012] Preferably, the data communication interface is connected to a host computer, and the data communication interface transmits the calibration parameters of the pressure calibration module to the control circuit through the host computer, thereby updating the calibration parameters of the pressure calibration module.

[0013] Preferably, the long-term stability index of the pressure calibration module is not less than ±0.2% FS / year.

[0014] The present invention also provides a secondary calibration method for an electronic capsule pressure sensor, the method using the above-described secondary calibration device for an electronic capsule pressure sensor, the method comprising the following steps:

[0015] Step S1: Calibrate the pressure calibration module and store the calibration data in the storage module;

[0016] Step S2: After the electronic capsule is opened, the output value of the pressure calibration module is stored in the storage module;

[0017] Step S3: Store the output value of the pressure detection module integrated inside the electronic capsule in the storage module;

[0018] Step S4: During the secondary calibration, first calculate the pressure value P detected by the pressure calibration module and the pressure value P detected by the electronic capsule. M The difference between the two measurements is the calibration pressure ΔP. After correcting all the measured pressure values ​​of the electronic capsule with the calibration pressure ΔP, the calibrated pressure measurement value of the electronic capsule is obtained.

[0019] Preferably, the pressure sensor module integrated in the electronic capsule in step S1 is calibrated after assembly. Based on the calibration data, its input-output curve is fitted and expressed as follows:

[0020] y1=αx1+β Formula 1

[0021] α and β are stored in the storage module as calibration parameters for the electronic capsule pressure sensor.

[0022] Preferably, before use, the electronic capsule pressure sensor secondary calibration device in step S2 needs to calibrate the pressure calibration module; based on the calibrated pressure data, a curve is fitted, represented as:

[0023] y2=kx2+l Formula 2

[0024] k and l are stored in the storage module as calibration parameters of the pressure calibration module.

[0025] Preferably, in step S3, when the pressure sensor of the electronic capsule is calibrated for the second time, the electronic capsule and the second calibration device exist in the same pressure environment, and the control circuit will simultaneously record the output x1 of the pressure sensor integrated in the electronic capsule and the output x2 of the pressure calibration module in the second calibration device.

[0026] Preferably, in step S4, the pressure value y2 detected by the secondary calibration device is regarded as the actual pressure.

[0027] Δy=y2-y1

[0028] This refers to the measurement deviation of the pressure sensor integrated into the electronic capsule; by correcting Equation 1, we obtain:

[0029] y′1=αx1+β+Δy Formula 3

[0030] All the data collected by the electronic capsule stored in the storage module were corrected according to Formula 3 to obtain the calibrated electronic capsule pressure measurement value.

[0031] Compared with the prior art, the present invention has the following beneficial effects:

[0032] The electronic capsule pressure sensor secondary calibration device and method of the present invention can perform secondary calibration on the pressure value detected by the electronic capsule, thereby reducing the measurement error caused by long-term storage of the electronic capsule. Attached Figure Description

[0033] Other features, objects, and advantages of the present invention will become more apparent from the following detailed description of non-limiting embodiments with reference to the accompanying drawings:

[0034] Figure 1 This is a schematic diagram of the secondary calibration device for the electronic capsule pressure sensor, as exemplified by the present invention.

[0035] Figure 2 This is a surface structure diagram of the secondary calibration device for the electronic capsule pressure sensor, an example of the present invention.

[0036] in:

[0037] Outer shell 1, vents 5

[0038] Control circuit 2; Data communication interface 6

[0039] Battery pack 3 Storage module 7

[0040] Pressure calibration module 4 System status indicator 8

[0041] Button 9 Detailed Implementation

[0042] The present invention will now be described in detail with reference to specific embodiments. These embodiments will help those skilled in the art to further understand the present invention, but do not limit the invention in any way. It should be noted that those skilled in the art can make several changes and improvements without departing from the concept of the present invention. These all fall within the protection scope of the present invention.

[0043] Example 1:

[0044] According to the present invention, a secondary calibration device for an electronic capsule pressure sensor includes a control circuit 2, a battery pack 3, a storage module 7, a pressure calibration module 4, an air vent 5, a data communication interface 6, and a housing 1. The housing 1 internally contains the control circuit 2, the battery pack 3, the pressure calibration module 4, the air vent 5, the data communication interface 6, and the storage module 7. The battery pack 3 is connected to the control circuit 2. The pressure calibration module 4 is connected to the control circuit 2. The air vent 5 is disposed on the housing 1. The storage module 7 receives pressure data detected by the electronic capsule and stores the calibration parameters of the pressure calibration module 4 and the integrated pressure sensor of the electronic capsule. The data communication interface 6 records the latest calibration parameters in the storage module 7.

[0045] The outer casing 1 has a system status indicator light 8 and a button 9 on its surface; the system status indicator light 8 and button 9 are connected to the control circuit 2 via a data cable. The pressure detected by the pressure calibration module 4 is transmitted to the control circuit 2 via a data bus and stored in the storage module 7. The data communication interface 6 is connected to a host computer, which transmits the calibration parameters of the pressure calibration module 4 to the control circuit 2 and updates the calibration parameters of the pressure calibration module 4. The long-term stability index of the pressure calibration module 4 is not less than ±0.2% FS / year.

[0046] The present invention also provides a secondary calibration method for an electronic capsule pressure sensor, the method using the above-described secondary calibration device for an electronic capsule pressure sensor, the method comprising the following steps:

[0047] Step S1: Calibrate the pressure calibration module 4 and store the calibration data in the storage module 7; the pressure sensor module integrated in the electronic capsule is calibrated after assembly, and based on the calibration data, its input-output curve is fitted and expressed as:

[0048] y1=αx1+β Formula 1

[0049] α and β are stored in storage module 7 as calibration parameters for the electronic capsule pressure sensor.

[0050] Step S2: After the electronic capsule is opened, the output value of the pressure calibration module 4 is stored in the storage module 7; before use, the secondary calibration device for the electronic capsule pressure sensor needs to calibrate the pressure calibration module 4; based on the calibrated pressure data, a curve is fitted, as shown below:

[0051] y2=kx2+l Formula 2

[0052] k and l are stored in storage module 7 as calibration parameters of pressure calibration module 4.

[0053] Step S3: Store the output value of the pressure detection module integrated in the electronic capsule in the storage module 7; when the pressure sensor of the electronic capsule is calibrated for the second time, the electronic capsule and the second calibration device exist in the same pressure environment, and the control circuit 2 will simultaneously record the output x1 of the pressure sensor integrated in the electronic capsule and the output x2 of the pressure calibration module 4 in the second calibration device.

[0054] Step S4: During the secondary calibration, first calculate the pressure value P detected by the pressure calibration module 4 and the pressure value P detected by the electronic capsule. M The difference between the two measured values ​​is the calibration pressure ΔP. After correcting all measured pressure values ​​of the electronic capsule with the calibration pressure ΔP, the calibrated pressure measurement value of the electronic capsule is obtained. The pressure value y2 detected by the secondary calibration device is regarded as the true pressure.

[0055] Δy=y2-y1

[0056] This refers to the measurement deviation of the pressure sensor integrated into the electronic capsule; by correcting Equation 1, we obtain:

[0057] y′1=αx1+β+Δy Formula 3

[0058] All the data collected by the electronic capsule stored in storage module 7 were corrected according to formula 3 to obtain the calibrated electronic capsule pressure measurement value.

[0059] Example 2:

[0060] The purpose of this invention is to provide a secondary calibration device and method for an electronic capsule pressure sensor, which enables secondary calibration of the pressure sensor integrated in the electronic capsule before use, thereby improving the accuracy of data collected by the electronic capsule system.

[0061] To achieve the above objectives, the present invention provides the following technical solution: a secondary calibration device for an electronic capsule pressure sensor, comprising a control circuit, a battery pack, a storage module, a pressure calibration module, vents, a data communication interface, and a housing. The pressure calibration module exhibits excellent long-term stability. Vents on the housing ensure that the environmental pressure of the pressure calibration module is the same as the external atmospheric pressure.

[0062] The secondary calibration method for electronic capsule pressure sensors includes the following specific implementation steps:

[0063] Step 1: Calibrate the pressure calibration module and store the calibration data in the storage module;

[0064] Step 2: After the electronic capsule is opened, the output value of the pressure calibration module is stored in the storage module;

[0065] Step 3: Store the output value of the pressure detection module integrated inside the electronic capsule in the storage module as well;

[0066] Step 4: During the secondary calibration, first calculate the pressure value P detected by the pressure calibration module and the pressure value P detected by the electronic capsule. M The difference between the two measurements is the calibration pressure ΔP. After correcting all the pressure values ​​measured by the electronic capsule with the calibration pressure ΔP, the true pressure value measured by the electronic capsule can be obtained.

[0067] like Figure 1 As shown in the figure, the principle block diagram of the secondary calibration device for the electronic capsule pressure sensor according to the embodiment of the present invention includes a housing 1, a control circuit 2, a battery pack 3, a pressure calibration module 4, an air vent 5, a data communication interface 6, and a storage module 7. Figure 2 The surface structure of the electronic capsule pressure sensor secondary calibration device shown includes a housing 1, a system status indicator light 8, and a button 9.

[0068] The electronic capsule pressure sensor secondary calibration device not only has the calibration function of the electronic capsule pressure sensor, but also has the function of receiving and recording the data transmitted from the electronic capsule.

[0069] The battery pack 3 is connected to the control circuit 2 and provides power to the system.

[0070] The pressure calibration module 4 is connected to the control circuit 2. The pressure detected by the pressure calibration module 4 is transmitted to the control circuit 2 via the data bus and stored in the storage module 7.

[0071] The vent 5 ensures that the environmental pressure of the pressure calibration module 4 is consistent with the environmental pressure of the electronic capsule being calibrated.

[0072] The data communication interface 6 can be connected to a host computer, which can transmit the calibration parameters of the pressure calibration module 4 to the control circuit 2, and can update the calibration parameters of the pressure calibration module 4 from time to time to ensure the accuracy of its pressure detection.

[0073] The storage module 7 is mainly used to receive pressure data detected by the electronic capsule, and also stores the calibration parameters of the pressure calibration module 4 and the integrated pressure sensor of the electronic capsule.

[0074] The system status indicator light 8 and the button 9 are connected to the control circuit 2 via a data cable to display the system's working status and control the system's operation.

[0075] The specific implementation of the secondary calibration method for the electronic capsule pressure sensor is as follows:

[0076] Step 1: After the pressure sensor module integrated in the electronic capsule is assembled, it is calibrated. Based on the calibration data, its input-output curve can be fitted and expressed as y1=αx1+β (Formula 1), where α and β are stored in the storage module 7 as calibration parameters of the electronic capsule pressure sensor.

[0077] Step two: Before using the electronic capsule pressure sensor secondary calibration device, the pressure calibration module 4 also needs to be calibrated. Based on the calibrated pressure data, a curve can be fitted, which can be expressed as y2=kx2+l (Formula 2), where k and l are stored in the storage module 7 as calibration parameters of the pressure calibration module 4.

[0078] Step 3: When performing secondary calibration on the electronic capsule pressure sensor, both the electronic capsule and the secondary calibration device exist in the same pressure environment. The control circuit 2 will simultaneously record the output x1 of the pressure sensor integrated in the electronic capsule and the output x2 of the pressure calibration module 4 in the secondary calibration device.

[0079] Step four: Before processing the gastrointestinal pressure data collected by the electronic capsule in the computer, the four parameter values ​​α, β, k, and l stored in the storage module 7 must first be read. Based on x1 and formula (1), the pressure value y1 detected at the time of electronic capsule calibration can be calculated; based on x2 and formula (2), the pressure value y2 detected by the secondary calibration device at the time of calibration can be calculated.

[0080] Step 5: Since the pressure calibration module 4 in the secondary calibration device has excellent long-term stability and can be calibrated multiple times, the pressure value y2 detected by the secondary calibration device can be regarded as the real pressure. Then, Δy = y2 - y1 is the measurement deviation of the integrated pressure sensor of the electronic capsule.

[0081] Step six, after correcting formula (1), we can get y′1=αx1+β+Δy (formula 3). After correcting all the data collected by the electronic capsule stored in the storage module 7 according to formula (3), we get the calibrated electronic capsule pressure measurement value.

[0082] This completes the entire secondary calibration process for the integrated pressure sensor in the electronic capsule.

[0083] The apparatus and method proposed in this invention can effectively reduce measurement errors caused by long-term storage of self-encapsulated pressure sensors in electronic capsules. This device is integrated with the electronic capsule data receiving device to achieve automatic acquisition of secondary calibration data, making it convenient to use. Algorithm compensation can effectively improve the measurement accuracy of the calibrated pressure sensor.

[0084] This invention provides a secondary calibration device and method for an electronic capsule pressure sensor. The housing contains a control circuit, a battery pack, a pressure calibration module, an air vent, a data communication interface, and a storage module. The housing surface is equipped with system status indicator lights and buttons. The pressure calibration module exhibits excellent long-term stability, with a long-term stability index of no less than ±0.2%FS / year. The pressure calibration module can be repeatedly calibrated periodically, and the latest calibration parameters are recorded in the storage module via the data communication interface to ensure the accuracy of its secondary calibration. The air vent ensures that the ambient air pressure of the pressure calibration module is consistent with the ambient air pressure of the electronic capsule. The secondary calibration method simultaneously records the pressure values ​​collected by the electronic capsule and the secondary calibration device, and uses the difference between the two as a secondary calibration parameter to correct the detection value of the integrated pressure sensor in the electronic capsule.

[0085] Those skilled in the art can understand this embodiment as a more specific description of Embodiment 1.

[0086] Those skilled in the art will understand that, besides implementing the system and its various devices, modules, and units provided by this invention in the form of purely computer-readable program code, the same functions can be achieved entirely through logical programming of the method steps, making the system and its various devices, modules, and units of this invention function in the form of logic gates, switches, application-specific integrated circuits, programmable logic controllers, and embedded microcontrollers. Therefore, the system and its various devices, modules, and units provided by this invention can be considered as a hardware component, and the devices, modules, and units included therein for implementing various functions can also be considered as structures within the hardware component; alternatively, the devices, modules, and units for implementing various functions can be considered as both software modules implementing the method and structures within the hardware component.

[0087] Specific embodiments of the present invention have been described above. It should be understood that the present invention is not limited to the specific embodiments described above, and those skilled in the art can make various changes or modifications within the scope of the claims, which do not affect the essence of the present invention. Unless otherwise specified, the embodiments and features described in this application can be arbitrarily combined with each other.

Claims

1. A secondary calibration method for an electronic capsule pressure sensor, characterized in that, include: The electronic capsule pressure sensor secondary calibration device includes a control circuit (2), a battery pack (3), a storage module (7), a pressure calibration module (4), an air vent (5), a data communication interface (6), and a shell (1). The housing (1) contains a control circuit (2), a battery pack (3), a pressure calibration module (4), an air vent (5), a data communication interface (6), and a storage module (7); the air vent (5) is located on the housing (1); the storage module (7) receives pressure data detected by the electronic capsule and stores the calibration parameters of the pressure calibration module (4) and the integrated pressure sensor of the electronic capsule; the data communication interface (6) records the latest calibration parameters in the storage module (7); The long-term stability index of the pressure calibration module (4) is not less than ±0.2% FS / year; The method includes the following steps: Step S1: Calibrate the pressure calibration module (4) and store the calibration data in the storage module (7); Step S2: After the electronic capsule is opened, the output value of the pressure calibration module (4) is stored in the storage module (7); Step S3: Store the output value of the pressure detection module integrated in the electronic capsule in the storage module (7); Step S4: During the secondary calibration, first calculate the pressure value detected by the pressure calibration module (4). Pressure values ​​detected by electronic capsules The difference between the two measurements is the calibration pressure. Compare all pressure values ​​measured by the electronic capsule with the calibration pressure. After correction, the calibrated electronic capsule pressure measurement value is obtained; In step S3, when the pressure sensor of the electronic capsule is calibrated for the second time, the electronic capsule and the second calibration device exist in the same pressure environment, and the control circuit (2) will simultaneously record the output of the pressure sensor integrated in the electronic capsule. The output of the pressure calibration module (4) in the secondary calibration device ; The pressure sensor module integrated in the electronic capsule in step S1 is calibrated after assembly. Based on the calibration data, its input-output curve is fitted and expressed as follows: in and The calibration parameters of the electronic capsule pressure sensor are stored in the storage module (7); Before use, the electronic capsule pressure sensor secondary calibration device in step S2 needs to calibrate the pressure calibration module (4); based on the calibrated pressure data, a curve is fitted, which is expressed as: in and The calibration parameters of the pressure calibration module (4) are stored in the storage module (7); Step S4 involves measuring the pressure value detected by the secondary calibration device. Consider it real pressure. This refers to the measurement deviation of the pressure sensor integrated into the electronic capsule; by correcting Equation 1, we obtain: The data collected by the electronic capsule stored in the storage module (7) is corrected according to Formula 3 to obtain the calibrated electronic capsule pressure measurement value.

2. The secondary calibration method for the electronic capsule pressure sensor according to claim 1, characterized in that, The battery pack (3) is connected to the control circuit (2); the pressure calibration module (4) is connected to the control circuit (2).

3. The secondary calibration method for the electronic capsule pressure sensor according to claim 1, characterized in that, The outer casing (1) is provided with a system status indicator (8) and a button (9), which are connected to the control circuit (2) via a data cable.

4. The secondary calibration method for the electronic capsule pressure sensor according to claim 1, characterized in that, The pressure detected by the pressure calibration module (4) is transmitted to the control circuit (2) via the data bus and stored in the storage module (7).

5. The secondary calibration method for the electronic capsule pressure sensor according to claim 1, characterized in that, The data communication interface (6) is connected to a host computer. The data communication interface (6) transmits the calibration parameters of the pressure calibration module (4) to the control circuit (2) through the host computer and updates the calibration parameters of the pressure calibration module (4).

Images