A prosthetic valve device

Abstract

The present application relates to the technical field of medical devices, and discloses an artificial valve device. The first end of the first mesh unit and the first end of the second mesh unit are spaced apart from each other in a preset direction, and the second end of the first mesh unit and the second end of the second mesh unit are spaced apart from each other in the preset direction. The present application is provided with the corresponding end portions of the first mesh unit and the second mesh unit being spaced apart from each other in the preset direction, so that the corresponding end portions of the first mesh unit and the second mesh unit are staggered in the preset direction, which is beneficial to reducing the limit diameter size of the compressed artificial valve device, i.e. the artificial valve device can be compressed to a smaller diameter size, and further beneficial to reducing the difficulty of sheathing the artificial valve device.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to an artificial valve device. BACKGROUND

[0002] The aortic valve is a three-leaflet valve located between the left ventricular outflow tract and the ascending aorta. The main function of the valve is to maintain effective left ventricular ejection. Under many pathological conditions, the valve is affected and various abnormalities occur. Aortic valve disease is a common disease in the clinical work of cardiologists and cardiac surgeons, mainly because of its high incidence in the elderly population. The treatment methods for severe aortic valve disease include valve surgical repair or replacement surgery, etc. The standard surgical treatment strategies include aortic valve repair, valve protection technology and aortic valve replacement technology, etc.

[0003] Aortic valve disease includes aortic valve stenosis and aortic valve insufficiency, etc., and in most cases, both coexist. Aortic valve stenosis accounts for the majority of aortic valve disease, with an incidence of 1-2% in people over the age of 65, and 4% in people over the age of 85.

[0004] The technical principle of transcatheter aortic valve replacement (TAVR) is to compress and load a fixed stent with an artificial valve into a delivery system, then send it along an access (such as an artery) to the aortic valve and release it, squeeze the diseased aortic valve next to the artificial valve, and fix the artificial aortic valve at the aortic valve to replace the diseased aortic valve.

[0005] However, the current artificial valve stent, due to unreasonable structural design, still has a relatively large limit diameter size after compression, which is not convenient for loading the artificial valve stent into the delivery system and is not conducive to the operation. SUMMARY

[0006] Therefore, the technical problem to be solved by the present application is to provide an artificial valve device which can reduce the limit diameter size of the artificial valve device after compression.

[0007] To solve the above technical problems, one technical solution of the present application is to provide an artificial valve device. The artificial valve device comprises a stent, the stent has a blood flow inlet end and a blood flow outlet end, and the blood flow inlet end and the blood flow outlet end are oppositely arranged along a preset direction. The stent comprises a plurality of mesh structure layers distributed layer by layer along the preset direction, at least part of the mesh structure layers are target mesh structure layers, the target mesh structure layers comprise first mesh hole units and second mesh hole units, the first mesh hole units and the second mesh hole units are adjacent to each other in a preset circumferential direction, wherein the preset direction is perpendicular to a plane defined by the preset circumferential direction. The first mesh hole unit and the second mesh hole unit each have a first end facing the blood flow inlet end and a second end facing the blood flow outlet end, the first end of the first mesh hole unit and the first end of the second mesh hole unit are spaced apart from each other in the preset direction, and the second end of the first mesh hole unit and the second end of the second mesh hole unit are spaced apart from each other in the preset direction. The artificial valve device further comprises a valve connected to the stent.

[0008] In an embodiment of the present application, the first end of the first mesh hole unit is closer to the blood flow inlet end than the first end of the second mesh hole unit, and the second end of the first mesh hole unit is closer to the blood flow outlet end than the second end of the second mesh hole unit.

[0009] In an embodiment of the present application, the mesh structure layer adjacent to the target mesh structure layer is connected to the first end of the first mesh hole unit or to the second end of the second mesh hole unit.

[0010] In an embodiment of the present application, when the mesh structure layer adjacent to the target mesh structure layer is connected to the first end of the first mesh hole unit, the valve is sewn to the stent through the first mesh hole unit; and when the mesh structure layer adjacent to the target mesh structure layer is connected to the second end of the second mesh hole unit, the valve is sewn to the stent through the second mesh hole unit.

[0011] In an embodiment of the present application, the first end of the first mesh hole unit is closer to the blood flow inlet end than the first end of the second mesh hole unit, and the second end of the first mesh hole unit is closer to the blood flow outlet end than the second end of the second mesh hole unit.

[0012] In an embodiment of the present application, the mesh structure layer adjacent to the target mesh structure layer comprises a connecting portion and at least two support rod portions, the at least two support rod portions are sequentially and spacedly distributed along the preset circumferential direction, and the connecting portion is arranged between any two adjacent support rod portions; the support rod portion is connected to the first mesh hole unit, and the connecting portion is recessed towards the target mesh structure layer.

[0013] In an embodiment of the present application, the connecting portion comprises a first connecting rod portion and a second connecting rod portion, the first connecting rod portion connects the second connecting rod portion, and the first connecting rod portion further connects the support rod portion on one side of the connecting portion, and the second connecting rod portion further connects the support rod portion on the other side of the connecting portion; wherein the length of the first connecting rod portion and the length of the second connecting rod portion are both less than the length of the support rod portion.

[0014] In an embodiment of the present application, the mesh structure layer adjacent to the target mesh structure layer comprises a connecting portion and at least two support rod portions, the at least two support rod portions are sequentially and spacedly distributed along a preset circumferential direction, and the connecting portion is arranged between any two adjacent support rod portions; the support rod portion connects the second mesh cell, and the connecting portion protrudes away from the target mesh structure layer.

[0015] In an embodiment of the present application, the mesh structure layer adjacent to the target mesh structure layer comprises a connecting portion; and the connecting portion is arranged between any two adjacent first mesh cells.

[0016] In an embodiment of the present application, the mesh structure layer comprises at least two mesh cells sequentially distributed along a preset circumferential direction; and the density of the mesh cells of the mesh structure layer close to the blood flow outflow end is greater than the density of the mesh cells of the mesh structure layer close to the blood flow inflow end.

[0017] The present application has the following beneficial effects: Different from the prior art, the present application provides an artificial valve device. The artificial valve device comprises a stent, and the stent comprises a plurality of mesh structure layers sequentially distributed along a preset direction. At least part of the mesh structure layers is a target mesh structure layer, and the first mesh cell and the second mesh cell of the target mesh structure layer both have a first end facing the blood flow inflow end and a second end facing the blood flow outflow end.

[0018] The first end of the first mesh cell and the first end of the second mesh cell are spaced apart from each other in the preset direction, and the second end of the first mesh cell and the second end of the second mesh cell are spaced apart from each other in the preset direction. Since the size of the end portion of the first mesh cell and the second mesh cell is greater than the size of other positions of the first mesh cell and the second mesh cell after the stent is compressed, the present application arranges the end portions corresponding to the first mesh cell and the second mesh cell to be spaced apart from each other in the preset direction, so that the end portions corresponding to the first mesh cell and the second mesh cell are staggered in the preset direction, which is beneficial to reduce the limit diameter size of the artificial valve device after compression, i.e., the artificial valve device can be compressed to a smaller diameter size, and thus the difficulty of sheathing the artificial valve device is reduced. BRIEF DESCRIPTION OF DRAWINGS

[0019] The accompanying drawings, which are incorporated herein and constitute part of this specification, illustrate embodiments consistent with the application and serve to explain the principles of the application. Together with the general description of the application given above, the drawings serve to explain the principles of the application.

[0020] Figure 1 is a structural schematic diagram of an embodiment of the artificial valve device of the present application;

[0021] Figure 2 is a structural schematic diagram of a first embodiment of the stent of the present application;

[0022] Figure 3 is a structural schematic diagram of the stent of the present application in a compressed state;

[0023] Figure 4 is a structural schematic diagram of the stent of the present application in an expanded state; Figure 2

[0024] Figure 5 is a structural schematic diagram of a second embodiment of the stent of the present application in an expanded state;

[0025] Figure 6 is a structural schematic diagram of a third embodiment of the stent of the present application in an expanded state;

[0026] Figure 7 is a structural schematic diagram of a fourth embodiment of the stent of the present application in an expanded state. DETAILED DESCRIPTION

[0027] In order to make the objects, technical solutions and advantages of the present application clearer, the following will be combined with the embodiments of the present application to make a clear and complete description of the technical solutions in the embodiments of the present application. Obviously, the described embodiments are a part of the embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those of ordinary skill in the art without creative work fall within the protection scope of the present application. The following embodiments and features in the embodiments can be combined with each other without conflict.

[0028] ​To solve the technical problem of a large diameter size of a prosthesis stent after compression in the prior art, an embodiment of the present application provides a prosthesis device. The prosthesis device comprises a stent, the stent having a blood flow inlet end and a blood flow outlet end, the blood flow inlet end and the blood flow outlet end being oppositely arranged along a preset direction. The stent comprises a plurality of mesh structure layers distributed layer by layer along the preset direction, at least part of the mesh structure layers being target mesh structure layers, the target mesh structure layers comprising first mesh cell units and second mesh cell units, the first mesh cell units and the second mesh cell units being adjacent to each other in a preset circumferential direction, wherein the preset direction is perpendicular to a plane defined by the preset circumferential direction. The first mesh cell units and the second mesh cell units each have a first end facing the blood flow inlet end and a second end facing the blood flow outlet end, the first end of the first mesh cell unit and the first end of the second mesh cell unit being spaced apart from each other in the preset direction, and the second end of the first mesh cell unit and the second end of the second mesh cell unit being spaced apart from each other in the preset direction. The prosthesis device further comprises a valve connected to the stent. Details are described below.

[0029] Referring to Figure 1 , Figure 1 is a structural schematic diagram of an embodiment of the prosthesis device of the present application.

[0030] In an embodiment, the prosthesis device can be applied to transcatheter aortic valve replacement, etc., specifically, the prosthesis device can be compressed and loaded into a delivery system, then delivered along an access to the aortic valve and released at the aortic valve, so that the prosthesis device expands to squeeze the diseased aortic valve aside, and then the prosthesis device is anchored at the aortic valve to replace the diseased aortic valve.

[0031] Specifically, the prosthesis device comprises a stent 10 and a valve 20. The stent 10 is used to anchor the valve 20 at a patient. To adapt to transcatheter aortic valve replacement, the stent 10 of the present embodiment can be compressed and expanded, that is, the stent 10 of the present embodiment allows to be compressed and loaded into a delivery system, and allows to expand at the patient so that the stent 10 is anchored at the patient. The valve 20 is connected to the stent 10, and the valve 20 can be anchored at the patient together with the stent 10 to replace the diseased aortic valve.

[0032] Further, the valve 20 can be connected to the stent 10 by sewing, welding, etc. The stent 10 can be provided with a fixing hole, and the valve 20 is connected to the stent 10 through the fixing hole. Of course, in other embodiments of the present application, the valve 20 can be directly connected to the stent 10, and the stent 10 is not provided with the fixing hole.

[0033] Referring to Figure 2 , Figure 2 is a structural schematic diagram of a first embodiment of the stent of the present application.

[0034] In one embodiment, the stent 10 has a blood inflow end A and a blood outflow end B, the blood inflow end A and the blood outflow end B being aligned in a predetermined direction (e.g., Figure 2 (As indicated by the middle arrow X, the same applies below) Relative settings.

[0035] The support 10 includes several mesh structure layers (including the first mesh structure layer, the second mesh structure layer, etc., hereinafter referred to as such) distributed layer by layer along a preset direction. At least a portion of the mesh structure layers is a target mesh structure layer, which includes a first mesh unit 31 and a second mesh unit 32. The first mesh unit 31 and the second mesh unit 32 are arranged along a preset circumferential direction (e.g., ...). Figure 2 As indicated by the middle arrow O (the same applies below), the first mesh unit 31 and the second mesh unit 32 are adjacent to each other in a preset circumferential direction, wherein the preset direction is perpendicular to the plane defined by the preset circumferential direction.

[0036] Please refer to the following: Figure 3 The mesh unit 10a of the stent 10 faces the end 10b of the blood flow inlet A and the blood flow outlet B. Figure 3 An illustrative example shows that the end 10b, facing the blood flow inlet A), typically retains a certain curvature after the stent 10 is compressed, meaning the end 10b of the mesh unit 10a cannot be compressed to its limit. This limit refers to the rods 10c on both sides of the end 10b of the mesh unit 10a being tightly pressed together. If the end 10b of the mesh unit 10a retains a certain curvature, it means the rods 10c on both sides of the end 10b of the mesh unit 10a cannot be tightly pressed together. This implies that the length of the end 10b of the mesh unit 10a in the aforementioned preset circumferential direction will be relatively large, typically reaching 0.8 mm. Other parts of the mesh unit 10a, except for the end 10b, can be compressed to their limit, and their length in the aforementioned preset circumferential direction can be compressed to a smaller size, typically down to 0.6 mm. In other words, after the stent 10 is compressed, the size of the end 10b of the mesh unit 10a will be larger than other parts of the mesh unit 10a except for the end 10b.

[0037] In this embodiment, both the first mesh unit 31 and the second mesh unit 32 have a first end facing the blood inflow end A and a second end facing the blood outflow end B. Specifically, the first mesh unit 31 has a first end 311 and a second end 312, and the second mesh unit 32 has a first end 321 and a second end 322. The first end 311 of the first mesh unit and the first end 321 of the second mesh unit are spaced apart from each other in a preset direction, and the second end 312 of the first mesh unit and the second end 322 of the second mesh unit are also spaced apart from each other in a preset direction. This embodiment sets the corresponding ends of the first mesh unit 31 and the second mesh unit 32 to be spaced apart from each other in a preset direction, so that the corresponding ends of the first mesh unit 31 and the second mesh unit 32 are staggered in the preset direction. This is beneficial to reducing the ultimate diameter size of the artificial valve device after compression, that is, the artificial valve device can be compressed to a smaller diameter size, which in turn helps to reduce the difficulty of inserting the artificial valve device into the sheath.

[0038] Please see Figure 2 and Figure 4 , Figure 4 yes Figure 2 The diagram shows the unfolded structure of the support frame.

[0039] In one embodiment, the first end 311 of the first mesh unit is closer to the blood flow inlet end A than the first end 321 of the second mesh unit, and the second end 312 of the first mesh unit is also closer to the blood flow inlet end A than the second end 322 of the second mesh unit.

[0040] In the above manner, when the target reticular structure layer is connected to other reticular structure layers on the side near the blood flow inflow end A, such as Figure 4 As shown, the first end 321 of the second mesh unit can be kept away from the other mesh structure layers, thus avoiding interference or collision between the first end 321 of the second mesh unit and the other mesh structure layers after the stent 10 is compressed; and when the target mesh structure layer is connected to other mesh structure layers on the side away from the blood flow inlet A, the second end 312 of the first mesh unit can be kept away from the other mesh structure layers, thus avoiding interference or collision between the second end 312 of the first mesh unit and the other mesh structure layers after the stent 10 is compressed. This reduces the risk of wear caused by structural interference of the stent 10 and helps to ensure the overall reliability of the stent 10.

[0041] Furthermore, the mesh structure layer adjacent to the target mesh structure layer is connected to the first end 311 of the first mesh unit or to the second end 322 of the second mesh unit.

[0042] When the mesh structure layer adjacent to the target mesh structure layer is connected to the first end 311 of the first mesh unit, as follows: Figure 4As shown, the mesh structure layer avoids the first end 321 of the second mesh cell, so that interference or collision between the first end 321 of the second mesh cell and the mesh structure layer after the stent 10 is compressed can be avoided; and when the mesh structure layer adjacent to the target mesh structure layer is connected to the second end 322 of the second mesh cell, the mesh structure layer avoids the second end 312 of the first mesh cell, so that interference or collision between the second end 312 of the first mesh cell and the mesh structure layer after the stent 10 is compressed can be avoided, thereby reducing the risk of wear of the stent 10 due to structural interference, and facilitating to ensure the reliability of the stent 10 as a whole.

[0043] Further, for the case that the valve is connected to the stent 10 by sewing, when the mesh structure layer adjacent to the target mesh structure layer is connected to the first end 311 of the first mesh cell, as shown, the first mesh cell 31 has better rigidity and can play a good supporting role. The valve is connected to the stent 10 through the first mesh cell 31, so that the valve can be stably supported on the stent 10. Preferably, the valve is connected to the stent 10 through the first mesh cell 31, for example, the valve is sewn to the stent 10 through the first mesh cell 31, at this time at least part of the first mesh cell 31 acts as a fixing hole. Figure 4

[0044] When the mesh structure layer adjacent to the target mesh structure layer is connected to the second end 322 of the second mesh cell, the second mesh cell 32 has better rigidity and can play a good supporting role at this time. The valve is connected to the stent 10 through the second mesh cell 32, so that the valve can be stably supported on the stent 10. Preferably, the valve is connected to the stent 10 through the second mesh cell 32, for example, the valve is sewn to the stent 10 through the second mesh cell 32, at this time at least part of the second mesh cell 32 acts as a fixing hole.

[0045] It should be noted that for the case that the first end 311 of the first mesh cell is closer to the blood inflow end A than the first end 321 of the second mesh cell, and the second end 312 of the first mesh cell is also closer to the blood inflow end A than the second end 322 of the second mesh cell, the target mesh structure layer of the present embodiment can be located at the blood inflow end A (not shown), or at the blood outflow end B (as shown), i.e., the target mesh structure layer is closer to the blood inflow end A or closer to the blood outflow end B than other mesh structure layers of the stent 10, which is not limited herein. Figure 4

[0046] Please continue to refer to Figure 4 In an exemplary embodiment, the stent 10 comprises a first mesh structure layer 11 and a second mesh structure layer 12. The first mesh structure layer 11 and the second mesh structure layer 12 are sequentially arranged in the direction from the blood outflow end B to the blood inflow end A. ​​

[0047] The first mesh structure layer 11 in this embodiment is the target mesh structure layer as described in the above embodiments. The second mesh structure layer 12 also includes at least two mesh cell units arranged in sequence along the preset circumferential direction. The mesh cell units of the second mesh structure layer 12 are connected to the first ends 311 of the first mesh cell units of the first mesh structure layer 11.

[0048] The density of the mesh cell units of the mesh structure layer close to the blood flow outflow end B is greater than the density of the mesh cell units of the mesh structure layer close to the blood flow inflow end A. In this embodiment, the density of the mesh cell units of the first mesh structure layer 11 is greater than the density of the mesh cell units of the second mesh structure layer 12. In other words, the expansion amount of the mesh cell units in the first mesh structure layer 11 is smaller when the stent 10 expands, and the rigidity of the mesh cell units of the first mesh structure layer 11 is smaller, which is conducive to the first mesh structure layer 11 forming a trumpet-shaped structure after the stent 10 expands, thereby effectively plugging the lesion, and preventing paravalvular leakage.

[0049] Please refer to Figure 5 , Figure 5 is a schematic diagram of the expanded structure of the second embodiment of the stent of the present application.

[0050] In an embodiment, the first ends 311 of the first mesh cell units are close to the blood flow inflow end A relative to the first ends 321 of the second mesh cell units, and the second ends 312 of the first mesh cell units are close to the blood flow outflow end B relative to the second ends 322 of the second mesh cell units. Further, the middle positions of the first mesh cell units 31 in the preset direction are connected to the middle positions of the second mesh cell units 32 in the preset direction.

[0051] In this way, the second mesh cell units 32 do not substantially affect the length of the stent 10 in the preset direction, and the length of the first mesh cell units 31 in the preset direction is greater than the length of the second mesh cell units 32 in the preset direction, i.e., the length of the first mesh cell units 31 in the preset direction is greater. In this way, the length of the first mesh cell units 31 in the preset direction changes less with the expansion and compression of the stent 10, so that the length of the stent 10 in the axial direction (i.e., the preset direction) changes less during expansion, which is conducive to ensuring that the artificial valve device of this embodiment has good axial positioning performance, can ensure that the stent 10 is accurately anchored at the lesion, and reduces the risk of the stent 10 deviating from the lesion. Thus, this embodiment can improve the axial positioning performance of the artificial valve device.

[0052] Further, the mesh structure layer adjacent to the target mesh structure layer includes a connecting portion 13 and at least two support rod portions 14, the at least two support rod portions 14 being arranged in sequence and spaced apart along the preset circumferential direction, and the connecting portion 13 being arranged between any two adjacent support rod portions 14.

[0053] Please continue to refer to Figure 5In an exemplary embodiment, the stent 10 comprises a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are arranged in sequence along a direction from the blood outflow end B towards the blood inflow end A. The second mesh layer 12 in this embodiment is the target mesh layer as described in the above embodiments. The first mesh layer 11 comprises the connecting portion 13 and the at least two strut portions 14.

[0054] The strut portions 14 are connected to the first mesh cells 31, and at this time, there is sufficient space between the connecting portion 13 and the second mesh cells 32, so the connecting portion 13 protrudes towards the target mesh layer, and even after the stent 10 is compressed, the connecting portion 13 does not interfere with the second mesh cells 32. At the same time, when the stent 10 is expanded, the connecting portion 13 does not cause the length of the stent 10 in the preset direction to change, i.e., the embodiment can reduce the amount of change in the axial length of the stent 10 during expansion, which is beneficial to ensure that the artificial valve device of the embodiment has good axial positioning performance, can ensure that the stent 10 is accurately anchored at the patient site, and reduces the risk of the stent 10 deviating from the patient site, so the embodiment can improve the axial positioning performance of the artificial valve device.

[0055] Further, the connecting portion 13 comprises a first connecting rod portion 131 and a second connecting rod portion 132. The first connecting rod portion 131 is connected to the second connecting rod portion 132, and the first connecting rod portion 131 is further connected to the strut portions 14 on one side of the connecting portion 13, and the second connecting rod portion 132 is further connected to the strut portions 14 on the other side of the connecting portion 13. The length of the first connecting rod portion 131 and the length of the second connecting rod portion 132 are both less than the length of the strut portions 14.

[0056] It should be noted that the central axis of the strut portions 14 is parallel to the above-mentioned preset direction, and the length of the strut portions 14 should be understood as the length of the strut portions 14 in the preset direction.

[0057] In the above manner, after the stent 10 is compressed, the first connecting rod portion 131 and the second connecting rod portion 132 of the first mesh layer 11 do not interfere with the second mesh layer 12, which can reduce the risk of wear of the stent 10 due to structural interference, and is beneficial to ensure the reliability of the stent 10 as a whole.

[0058] Please refer to Figure 6 , Figure 6 is a schematic diagram of the expanded structure of the third embodiment of the stent of the present application.

[0059] In another exemplary embodiment, the stent 10 comprises a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are arranged in sequence along a direction from the blood flow out end B towards the blood flow in end A. The second mesh layer 12 in this embodiment is the target mesh layer as described in the above embodiments. The first mesh layer 11 comprises the connection portion 13 and at least two support rod portions 14.

[0060] The support rod portion 14 is connected to the second mesh unit 32. In order to avoid the connection portion 13 interfering with the first mesh unit 31 and causing abrasion, the connection portion 13 protrudes in a direction away from the target mesh layer. In this way, even after the stent 10 is compressed, the connection portion 13 will not interfere with the first mesh unit 31.

[0061] Please refer to Figure 7 , Figure 7 is a schematic diagram of an expanded structure of a fourth embodiment of the stent of the present application.

[0062] In another exemplary embodiment, the stent 10 comprises a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are arranged in sequence along a direction from the blood flow out end B towards the blood flow in end A.

[0063] The first mesh layer 11 in this embodiment is the target mesh layer as described in the above embodiments. The second mesh layer 12 comprises the connection portion 13. Any two adjacent first mesh units 31 in the first mesh layer 11 are connected by the connection portion 13.

[0064] It should be noted that for the case where the first end 311 of the first mesh unit is closer to the blood flow in end A relative to the first end 321 of the second mesh unit, and the second end 312 of the first mesh unit is closer to the blood flow out end B relative to the second end 322 of the second mesh unit, the target mesh layer in this embodiment can be located at the blood flow in end A or at the blood flow out end B, i.e. the target mesh layer is closer to the blood flow in end A or closer to the blood flow out end B relative to other mesh layers of the stent 10, which is not limited herein.

[0065] In summary, the artificial valve device provided by the application is characterized in that the first end of the first mesh unit and the first end of the second mesh unit are spaced apart from each other in a preset direction, and the second end of the first mesh unit and the second end of the second mesh unit are spaced apart from each other in the preset direction. Since the size of the end of the first mesh unit and the second mesh unit is larger than the size of other positions of the first mesh unit and the second mesh unit after the stent is compressed, the application is arranged to space apart the corresponding ends of the first mesh unit and the second mesh unit from each other in the preset direction, so that the corresponding ends of the first mesh unit and the second mesh unit are staggered with each other in the preset direction, which is beneficial to reduce the limit diameter size of the artificial valve device after compression, that is, the artificial valve device can be compressed to a smaller diameter size, and thus is beneficial to reduce the difficulty of sheathing the artificial valve device.

[0066] In addition, in the application, unless otherwise explicitly specified and limited, the terms "connected", "connected", "stacked" and the like should be understood in a broad sense, for example, can be fixedly connected, can be detachably connected, or integrated; can be directly connected, or indirectly connected through an intermediate medium; can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the application can be understood according to the specific circumstances.

[0067] Finally, it should be pointed out that: the above embodiments are only used to illustrate the technical solutions of the application, and not to limit them; although the application has been described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions recorded in the above embodiments, or make equivalent replacement for part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the application.

Claims

1. A prosthetic valve device, characterized by, The artificial valve device comprises: a stent having a blood flow inlet end and a blood flow outlet end, the blood flow inlet end and the blood flow outlet end being oppositely arranged along a preset direction; the stent comprises a plurality of mesh structure layers distributed layer by layer along the preset direction, at least part of the mesh structure layers being target mesh structure layers, the target mesh structure layers comprising first mesh cell units and second mesh cell units, the first mesh cell units and the second mesh cell units being adjacent to each other in a preset circumferential direction, wherein the preset direction is perpendicular to a plane defined by the preset circumferential direction; the first mesh cell units and the second mesh cell units each have a first end facing the blood flow inlet end and a second end facing the blood flow outlet end, the first end of the first mesh cell unit and the first end of the second mesh cell unit being spaced from each other in the preset direction, and the second end of the first mesh cell unit and the second end of the second mesh cell unit being spaced from each other in the preset direction; the first end of the first mesh cell unit is closer to the blood flow inlet end than the first end of the second mesh cell unit, and the second end of the first mesh cell unit is closer to the blood flow inlet end or the blood flow outlet end than the second end of the second mesh cell unit; a valve connected to the stent.

2. The artificial valve device according to claim 1, wherein a mesh structure layer adjacent to the target mesh structure layer is connected to the first end of the first mesh cell unit or to the second end of the second mesh cell unit.

3. The artificial valve device according to claim 2, wherein when the mesh structure layer adjacent to the target mesh structure layer is connected to the first end of the first mesh cell unit, the valve is connected to the stent through the first mesh cell unit; and when the mesh structure layer adjacent to the target mesh structure layer is connected to the second end of the second mesh cell unit, the valve is connected to the stent through the second mesh cell unit.

4. The artificial valve device according to claim 1, wherein the mesh structure layer adjacent to the target mesh structure layer comprises a connecting portion and at least two support rod portions, the at least two support rod portions being sequentially and spacedly arranged along the preset circumferential direction, and the connecting portion being arranged between any two adjacent support rod portions; the support rod portions are connected to the first mesh cell units, and the connecting portion protrudes towards the target mesh structure layer.

5. The artificial valve device according to claim 4, wherein the connecting portion comprises a first connecting rod portion and a second connecting rod portion, the first connecting rod portion being connected to the second connecting rod portion, and the first connecting rod portion being further connected to the support rod portion on one side of the connecting portion, and the second connecting rod portion being further connected to the support rod portion on the other side of the connecting portion; wherein the length of the first connecting rod portion and the length of the second connecting rod portion are both less than the length of the support rod portion.

6. The artificial valve device according to claim 1, wherein ​ The mesh structure layer adjacent to the target mesh structure layer comprises a connecting portion and at least two support rod portions, the at least two support rod portions are sequentially and spacedly distributed along the preset circumferential direction, and the connecting portion is arranged between any two adjacent support rod portions. The support rod portion is connected to the second mesh cell, and the connecting portion protrudes in a direction away from the target mesh structure layer.

7. The prosthetic valve device of claim 1, wherein: The mesh structure layer adjacent to the target mesh structure layer comprises a connecting portion; Any two adjacent first mesh cells are connected through the connecting portion.

8. The prosthetic valve device of any one of claims 1 to 7, wherein: The mesh structure layer comprises at least two mesh cells sequentially distributed along the preset circumferential direction; The density of the mesh cells of the mesh structure layer close to the blood outflow end is greater than the density of the mesh cells of the mesh structure layer close to the blood inflow end.

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