Aneurysm closure system

By using woven mesh-structured intra-aneurysm occlusion units and aneurysm neck occlusion units, combined with shape memory materials and coatings, the problems of large trauma and recurrence in aneurysm treatment have been solved, achieving a highly efficient and safe occlusion effect.

CN116407191BActive Publication Date: 2025-11-14SINOMED NEUROVITA TECH INC
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Patent Information

Application Number
CN202111643345.5
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-12-29
Publication Date
2025-11-14
Estimated Expiration
2041-12-29

AI Technical Summary

Technical Problem

Existing aneurysm treatment methods suffer from problems such as high trauma, high cost, and high recurrence rate, especially minimally invasive interventional treatment, which has a significant space-occupying effect.

Method used

The intra-aneurysmal occlusion unit and the aneurysm neck occlusion unit are made of a mesh structure formed by woven filaments. They are implanted into the aneurysm and the carrier vessel through a microcatheter, respectively adapting to the shape of the aneurysm and the aneurysm neck to form an occlusion. Combined with shape memory materials and coatings, they promote thrombus formation and endothelialization.

Benefits of technology

It achieves effective closure of aneurysms, reduces the risk of recurrence, minimizes the impact on the carrier vessels, and improves safety and closure efficacy.

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Abstract

This application discloses an aneurysm occlusion system, including an intra-aneurysm occlusion unit and an aneurysm neck occlusion unit. The intra-aneurysm occlusion unit is implanted into the aneurysm body via a microcatheter, and the shape of the intra-aneurysm occlusion unit is adapted to the shape of the aneurysm. The aneurysm neck occlusion unit is implanted into the carrier vessel via a microcatheter, and the aneurysm neck occlusion unit is fixedly connected to the intra-aneurysm occlusion unit. The aneurysm neck occlusion unit forms a seal on the aneurysm neck. Both the intra-aneurysm occlusion unit and the aneurysm neck occlusion unit are mesh structures woven from filaments. One technical advantage of this application is its highly rational structural design, simple operation, and ability to simultaneously occlude both the aneurysm body and the aneurysm neck, resulting in good occlusion efficacy and low recurrence rate. Furthermore, because this aneurysm occlusion system requires fewer implants within the carrier vessel, it has minimal impact on the carrier vessel and offers high safety.
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Description

Technical Field

[0001] This application belongs to the field of medical device technology, specifically, this application relates to an aneurysm closure system. Background Technology

[0002] Aneurysms are a very common vascular disease. Among cerebrovascular diseases, intracranial aneurysms are second only to cerebral thrombosis in incidence. Their occurrence is related to hypertension, cerebral arteriosclerosis, infection, and trauma, and they are most common in middle-aged and elderly people between 40 and 60 years old. Aneurysms are mainly characterized by an expansile, pulsating mass and can occur in any part of the arterial system. Rupture of an aneurysm can lead to serious consequences. For example, rupture of an intracranial aneurysm can cause subarachnoid hemorrhage, and in severe cases, can trigger vasospasm and cause extensive cerebral infarction, leading to hemiplegia and coma.

[0003] Currently, aneurysm treatment methods include: 1) Surgical treatment, such as aneurysm neck clipping, aneurysm neck ligation, and open suturing of giant aneurysms. This treatment method requires cutting through the superficial skin tissue to expose the artery, resulting in significant surgical trauma, substantial bleeding, and a long treatment time, which is very detrimental to the patient's recovery.

[0004] 2) Medical drug therapy: Traditional medical drug therapy is usually used for stable, unruptured aneurysms. The main purpose is to control potential risk factors that could induce aneurysm rupture, such as controlling the patient's blood pressure. This treatment method cannot effectively prevent aneurysm rupture and has poor treatment results.

[0005] 3) Minimally invasive interventional treatments, such as coil embolization, liquid glue embolization, and stent-assisted embolization. This treatment method has relatively lower risks, is safer, avoids complications caused by surgical trauma, and greatly improves patient prognosis.

[0006] However, the current drawbacks of minimally invasive media therapy are the space-occupying effect and the need for other stents, which increases the cost of treatment. Summary of the Invention

[0007] One objective of this application is to provide a new technical solution for an aneurysm closure system.

[0008] According to one aspect of the embodiments of this application, an aneurysm occlusion system is provided, comprising:

[0009] An intra-aneurysmal occlusion unit is implanted into the aneurysm via a microcatheter, and the shape of the intra-aneurysmal occlusion unit is adapted to the shape of the aneurysm.

[0010] A neck occlusion unit is implanted into the aneurysm-bearing vessel via a microcatheter and is fixedly connected to the intra-aneurysmal occlusion unit; the neck occlusion unit occludes the neck of the aneurysm.

[0011] The intratumoral occlusion unit and the aneurysm neck occlusion unit are both mesh structures woven from filaments.

[0012] Optionally, the intratumoral occlusion unit and the aneurysm neck occlusion unit are fixed outside the body and form an integrated structure, and the integrated structure is implanted into the body through a microcatheter.

[0013] Optionally, the intratumoral occlusion unit is woven to form an interlocking portion, which is connected to the aneurysm neck occlusion unit.

[0014] Optionally, the neck occlusion unit is woven to form an interlocking portion, which is connected to the intratumoral occlusion unit.

[0015] Optionally, the connecting portion is located in the middle of the aneurysm neck sealing unit.

[0016] Optionally, the number of the connecting parts is multiple.

[0017] Optionally, the outer surface of the intraneural plugging unit is fitted to the aneurysm cavity.

[0018] Optionally, the filaments are made of shape memory material;

[0019] After the intra-aneurysmal occlusion unit is implanted into the aneurysm body via a microcatheter and then released, the intra-aneurysmal occlusion unit can adapt to the shape of the aneurysm.

[0020] After the aneurysm neck occlusion unit is implanted into the carrier vessel of the aneurysm via a microcatheter and then released, the aneurysm neck occlusion unit can adapt to the shape of the carrier vessel.

[0021] Optionally, the aneurysm neck occlusion unit has a semi-circular curved surface structure on the carrier vessel, and the outer surface of the aneurysm neck occlusion unit is attached to the inner surface of the carrier vessel surrounding the aneurysm.

[0022] Optionally, the filament is made of shape memory alloy, shape memory ceramic, shape memory metal composite material, or shape memory polymer.

[0023] Optionally, the surface of the intratumoral occlusion unit is coated with a first coating layer, which is used to promote thrombus formation;

[0024] The surface of the aneurysm neck occlusion unit is coated with a second coating, which is used to promote endothelialization of the aneurysm neck occlusion unit or to prevent thrombosis.

[0025] One technical advantage of the embodiments of this application is that:

[0026] In this embodiment, the intra-aneurysmal occlusion unit and the neck occlusion unit are both mesh structures woven from filaments. The intra-aneurysmal occlusion unit is implanted into the aneurysm via a microcatheter, adapting its shape to the shape of the aneurysm. The neck occlusion unit is implanted into the carrier vessel via a microcatheter, thus occluding the neck of the aneurysm. Simultaneously, the neck occlusion unit is fixedly connected to the intra-aneurysmal occlusion unit. The intra-aneurysmal occlusion unit disrupts blood flow within the aneurysm, causing aneurysm embolization. Simultaneously, the neck occlusion unit, connected and fixed to the intra-aneurysmal unit, alters the blood flow direction of the carrier vessel at the neck opening. This coordinated action with the intra-aneurysmal occlusion unit effectively occludes the neck of the aneurysm, preventing the formation of new aneurysms at the neck opening.

[0027] Therefore, this aneurysm closure system can simultaneously occlude both the aneurysm body and neck, achieving excellent closure results and reducing the likelihood of recurrence. Furthermore, because the system requires minimal implantation within the parent vessel, it has minimal impact on the parent vessel, resulting in high safety and good postoperative outcomes.

[0028] Other features and advantages of this application will become clear from the following detailed description of exemplary embodiments with reference to the accompanying drawings. Attached Figure Description

[0029] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments of the present application and, together with their description, serve to explain the principles of the present application.

[0030] Figure 1 This is a schematic diagram of a first structure of the intra-aneurysmal occlusion unit and the aneurysmal neck occlusion unit of the aneurysm occlusion system provided in the embodiments of this application;

[0031] Figure 2 This is a reference diagram showing the first usage state of the aneurysm closure system provided in the embodiments of this application;

[0032] Figure 3 This is a second structural schematic diagram of the intra-aneurysmal occlusion unit and the aneurysmal neck occlusion unit of the aneurysm occlusion system provided in the embodiments of this application;

[0033] Figure 4 This is a reference diagram showing a third usage state of the aneurysm closure system provided in the embodiments of this application;

[0034] Figure 5 This is a second structural schematic diagram of the intra-aneurysmal occlusion unit and the aneurysmal neck occlusion unit of the aneurysm occlusion system provided in the embodiments of this application;

[0035] Figure 6This is a reference diagram showing a third usage state of the aneurysm closure system provided in the embodiments of this application;

[0036] Figure 7 This is a fourth structural schematic diagram of the intra-aneurysmal occlusion unit and the aneurysmal neck occlusion unit of the aneurysm occlusion system provided in the embodiments of this application;

[0037] Figure 8 This is a reference diagram showing the fourth usage state of the aneurysm closure system provided in the embodiments of this application.

[0038] In the figure: 1. Intratumoral occlusion unit; 2. Neck occlusion unit; 3. Tumor body; 4. Tumor-bearing vessel; 5. Connecting part. Detailed Implementation

[0039] Various exemplary embodiments of the present application will now be described in detail with reference to the accompanying drawings. It should be noted that, unless otherwise specifically stated, the relative arrangement, numerical expressions, and values ​​of the components and steps set forth in these embodiments do not limit the scope of the present application.

[0040] The embodiments of this application will now be described in detail. Examples of these embodiments are illustrated in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this application, and should not be construed as limiting this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.

[0041] The terms "first" and "second" in the specification and claims of this application may explicitly or implicitly include one or more of the features. In the description of this application, unless otherwise stated, "multiple" means two or more. Furthermore, "and / or" in the specification and claims indicates at least one of the connected objects, and the character " / " generally indicates that the preceding and following objects are in an "or" relationship.

[0042] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0043] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0044] like Figures 1 to 8 As shown, this application provides an aneurysm closure system. The aneurysm closure system includes an intra-aneurysm closure unit 1 and an aneurysm neck closure unit 2. The intra-aneurysm closure unit 1 is disposed within the aneurysm body 3 and is used to close the aneurysm; the aneurysm neck closure unit 2 is disposed in the carrier vessel 4 and is fixedly connected to the intra-aneurysm closure unit 1, and is used to close the aneurysm neck.

[0045] Specifically, the intra-aneurysmal occlusion unit 1 is implanted into the aneurysm body 3 via a microcatheter. After implantation, the shape of the intra-aneurysmal occlusion unit 1 conforms to the shape of the aneurysm, meaning it fits snugly against the inner surface of the aneurysm cavity. The intra-aneurysmal occlusion unit 1 can disrupt blood flow within the aneurysm and cause aneurysm embolization, thereby effectively sealing the aneurysm.

[0046] More specifically, the aneurysm neck occlusion unit 2 is implanted into the carrier vessel 4 via a microcatheter. After the aneurysm neck occlusion unit 2 is implanted into the carrier vessel 4, it is fixedly connected to the intra-aneurysm occlusion unit 1, and part of the outer surface of the aneurysm neck occlusion unit 2 is attached to the inner surface of the carrier vessel 4, so that the aneurysm neck occlusion unit 2 effectively occludes the aneurysm neck.

[0047] In this embodiment, the intra-aneurysmal occlusion unit 1 and the aneurysm neck occlusion unit 2 are both mesh structures woven from filaments. On the one hand, the mesh structure facilitates the occlusion of the aneurysm body 3 and the aneurysm neck; on the other hand, the mesh structure is lightweight, reducing patient discomfort. It should be noted that the aneurysm neck refers to the location where the aneurysm connects to the carrier vessel 4.

[0048] For example, the intra-aneurysmal occlusion unit 1 has both a compressed state and an expanded state. In its compressed state, the intra-aneurysmal occlusion unit 1 is smaller in volume, facilitating its implantation into the aneurysm body 3. After implantation, the intra-aneurysmal occlusion unit 1 expands in volume, thus achieving better occlusion of the aneurysm. The intra-aneurysmal occlusion unit 1 can be prefabricated according to the shape and size of the aneurysm. Preferably, the intra-aneurysmal occlusion unit 1 can be spherical or similar to a spherical shape, or umbrella-shaped or similar to an umbrella shape.

[0049] Similarly, the aneurysm neck occlusion unit 2 has both a compressed and an expanded state. In its compressed state, the aneurysm neck occlusion unit 2 is smaller in size, facilitating the implantation of the intra-aneurysm occlusion unit 1 into the carrier vessel 4. After implantation, the aneurysm neck occlusion unit 2 expands in size, effectively occluding the aneurysm neck. The aneurysm neck occlusion unit 2 can also be prefabricated according to the shape and size of the aneurysm.

[0050] In this embodiment, the intra-aneurysmal occlusion unit 1 and the aneurysm neck occlusion unit 2 are both mesh structures woven from filaments. The intra-aneurysmal occlusion unit 1 is implanted into the aneurysm body 3 via a microcatheter, adapting its shape to the shape of the aneurysm. The aneurysm neck occlusion unit 2 is implanted into the carrier vessel 4 via a microcatheter, thus occluding the aneurysm neck. Simultaneously, the aneurysm neck occlusion unit 2 is fixedly connected to the intra-aneurysmal occlusion unit 1. The intra-aneurysmal occlusion unit 1 disrupts blood flow within the aneurysm, causing aneurysm embolism. Meanwhile, the aneurysm neck occlusion unit 2, connected and fixed to the intra-aneurysmal occlusion unit 1, alters the blood flow direction of the carrier vessel 4 at the aneurysm neck, working in conjunction with the intra-aneurysmal occlusion unit 1 to effectively occlude the aneurysm neck, thereby preventing the formation of new aneurysms at the aneurysm neck.

[0051] Therefore, this aneurysm closure system can simultaneously occlude both the aneurysm body (3) and the aneurysm neck, achieving good closure results and reducing the likelihood of recurrence. Furthermore, because the system requires fewer implants within the parent vessel (4), it has minimal impact on the parent vessel, resulting in higher safety and better postoperative outcomes.

[0052] In some implementations, such as Figure 7 and Figure 8 As shown, the shape of the intra-aneurysmal occlusion unit 1 can be composed of a partial spherical structure. Simultaneously, this partial spherical structure is supported within the aneurysm cavity connected to the carrier vessel 4, thereby occluding the aneurysm. This also further reduces the volume of the aneurysm occlusion system. Figure 7 and Figure 8This only provides one connection method between the intraneural plugging unit 1 and the aneurysm neck plugging unit 2, which have a partially spherical structure. Of course, these two can also be connected in the second or third implementation method to achieve better sealing of the aneurysm by the aneurysm plugging system.

[0053] Optionally, refer to Figure 1 and Figure 2 The intratumoral occlusion unit 1 and the aneurysm neck occlusion unit 2 are fixed outside the body and form an integrated structure, which is then implanted into the body through a microcatheter.

[0054] In the above embodiments, since the intraneural occlusion unit 1 and the aneurysm neck occlusion unit 2 are fixed outside the body and form an integral structure, the connection method is relatively stable, effectively avoiding the separation between the two. At the same time, the integral structure is implanted into the body through a microcatheter, which is simple to operate and facilitates the accurate implantation of the integral structure into the accurate position, thereby facilitating the occlusion of the aneurysm by the aneurysm occlusion system.

[0055] For example, after the intra-aneurysmal occlusion unit 1 is woven, it will form a binding portion, and after the aneurysm neck occlusion unit 2 is woven, it will form a binding portion. These binding portions are used to fix the intra-aneurysmal occlusion unit 1 and the aneurysm neck occlusion unit 2 together, which helps to reduce the volume of the aneurysm occlusion system, facilitates the optimization of the aneurysm occlusion system's structure, and makes implantation easier. At the same time, it also makes the connection between the intra-aneurysmal occlusion unit 1 and the aneurysm neck occlusion unit 2 very stable.

[0056] Optionally, refer to Figure 5 and Figure 6 The intratumoral sealing unit 1 is woven to form a hook part 5, which hooks the tumor neck sealing unit 2.

[0057] In the above embodiment, a hooking part 5 is formed on the intratumoral occlusion unit 1. Moreover, the hooking part 5 is formed by weaving. The formation method of the hooking part 5 is relatively simple and facilitates the hooking and fixing between the intratumoral occlusion unit 1 and the cervical occlusion unit 2.

[0058] Optionally, refer to Figure 3 and Figure 4 The neck occlusion unit 2 is woven to form a hook part 5, which hooks the intratumoral occlusion unit 1.

[0059] In the above embodiment, a hooking part 5 is formed on the aneurysm neck occlusion unit 2. Moreover, the hooking part 5 is formed by weaving. The formation method of the hooking part 5 is relatively simple and facilitates the hooking and fixing between the aneurysm neck occlusion unit 1 and the aneurysm neck occlusion unit 2.

[0060] Optionally, the connecting portion 5 is located in the middle of the aneurysm neck occlusion unit 2. On the one hand, this allows the periphery of the aneurysm neck occlusion unit 2 to better fit with the carrier vessel 4, thereby changing the blood flow direction of the carrier vessel 4 at the aneurysm neck orifice, effectively occluding the aneurysm neck and preventing the formation of new aneurysms at the aneurysm neck orifice. On the other hand, it also helps to achieve a firm connection between the intra-aneurysm occlusion unit 1 and the aneurysm neck occlusion unit 2.

[0061] Optionally, the number of the connecting parts 5 is multiple. This allows for better fixation between the intra-aneurysmal occlusion unit 1 and the aneurysm neck occlusion unit 2, effectively preventing detachment between them and thus effectively occluding the aneurysm.

[0062] In this embodiment, the aneurysm occlusion system can simultaneously occlude the aneurysm body 3 and the aneurysm neck, with a good occlusion effect.

[0063] In some implementations, the aneurysm 3 occlusion unit and the aneurysm neck occlusion unit 2 can be integrally formed outside the body and then implanted inside the body; or they can be divided into two parts outside the body, implanted separately inside the body and then connected together. The specific choice can be made according to the patient's specific situation in order to better occlude the aneurysm.

[0064] Optionally, the outer surface of the intra-aneurysmal occlusion unit 1 is fitted to the aneurysm cavity. This allows the intra-aneurysmal occlusion unit 1 to effectively disrupt blood flow within the aneurysm and cause aneurysm embolization, thereby effectively occluding the aneurysm body 3.

[0065] Optionally, the filaments are made of shape memory material;

[0066] After the intra-aneurysmal occlusion unit 1 is implanted into the aneurysm body 3 via a microcatheter and then released, the intra-aneurysmal occlusion unit 1 can adapt to the shape of the aneurysm.

[0067] After the aneurysm neck occlusion unit 2 is implanted into the aneurysm-bearing vessel 4 via a microcatheter and released, the aneurysm neck occlusion unit 2 can adapt to the shape of the aneurysm-bearing vessel 4.

[0068] In the above embodiments, the intraneural occlusion unit 1 and the neck occlusion unit 2 are woven using shape memory material, which helps to reduce the volume of the intraneural occlusion unit 1 and the neck occlusion unit 2, making them easier to implant into the body. At the same time, it also facilitates the expansion of the intraneural occlusion unit 1 and the neck occlusion unit 2 after implantation, so as to better fit the intraneural occlusion unit 1 with the aneurysm cavity and the neck occlusion unit 2 with the aneurysm-bearing vessel 4, thereby enabling the aneurysm occlusion system to effectively occlude the aneurysm.

[0069] Optionally, the aneurysm neck occlusion unit 2 has a semi-circular curved surface structure on the carrier vessel 4, and the outer surface of the aneurysm neck occlusion unit 2 is fitted with the inner surface of the carrier vessel 4 surrounding the aneurysm. This makes the shape of the aneurysm neck occlusion unit 2 conform to the shape of the carrier vessel 4, which not only has less impact on the carrier vessel 4, but also effectively occludes the aneurysm neck.

[0070] Optionally, the filament is made of shape memory alloy, shape memory ceramic, shape memory metal composite material, or shape memory polymer. This allows the intra-aneurysmal occlusion unit 1 and the aneurysm neck occlusion unit 2 to effectively change between compressed and expanded states. It can be in a compressed state to meet implantation requirements, or in an expanded state to meet the requirements for expanding and occluding the aneurysm, making operation very convenient. This aneurysm occlusion system, after being implanted into the aneurysm through a microcatheter and released, can adapt to the morphology of the aneurysm, conforming well to the aneurysm, thereby effectively occluding the aneurysm.

[0071] In some embodiments, the filament may be a mixture of shape memory alloy and other materials. For example, the filament may be a mixture of shape memory alloy and precious metal, wherein the precious metal may be Pt-Ir, Pt-W, etc., and the precious metal filament serves as a contrast agent; or, the filament may be a mixture of shape memory alloy and nylon-like materials, wherein the nylon-like materials are used to accelerate thrombus formation; or, the filament may also be woven from a mixture of multiple materials.

[0072] Optionally, the surface of the intra-aneurysmal occlusion unit 1 is coated with a first coating layer, which is used to promote thrombus formation; wherein, the first coating layer can be a thrombin-like coating layer, thereby helping to improve the occlusion effect of the intra-aneurysmal occlusion unit 1, effectively avoiding aneurysm rupture, and improving the safety of the aneurysm occlusion system.

[0073] The surface of the aneurysm neck occlusion unit 2 is coated with a second coating that promotes endothelialization of the aneurysm neck occlusion unit, which helps reduce patient rejection after implantation of the aneurysm occlusion system; or, the second coating is used for antithrombotic purposes, which helps to further prevent the formation of new aneurysms at the aneurysm neck.

[0074] In the embodiments of this application, the aneurysm occlusion system can not only effectively reduce the space-occupying effect and save costs, but also adapt to aneurysms of different shapes and locations, and reduce the risk of delayed aneurysm rupture and avoid aneurysms that block other branches.

[0075] In addition, the aneurysm closure system has a very stable structure and is not easily displaced, which can effectively prevent aneurysm recurrence.

[0076] The aneurysm occlusion system provided in this application has a very reasonable structural design and is simple to operate. It can simultaneously occlude the aneurysm body 3 and the aneurysm neck, with good occlusion effect and low recurrence rate. In addition, because the aneurysm occlusion system requires fewer implants in the carrier vessel 4, it has minimal impact on the carrier vessel 4 and has high safety.

[0077] While specific embodiments of this application have been described in detail by way of examples, those skilled in the art should understand that the above examples are for illustrative purposes only and are not intended to limit the scope of this application. Those skilled in the art should understand that modifications can be made to the above embodiments without departing from the scope and spirit of this application. The scope of this application is defined by the appended claims.

Claims

1. An aneurysm occlusion system, characterized in that, include: Intra-aneurysmal occlusion unit (1), wherein the intra-aneurysmal occlusion unit (1) is implanted into the aneurysm body (3) through a microcatheter, and the shape of the intra-aneurysmal occlusion unit (1) is adapted to the shape of the aneurysm; Aneurysm neck occlusion unit (2) is implanted into the aneurysm-bearing vessel (4) through a microcatheter, and the aneurysm neck occlusion unit (2) forms an occlusion on the aneurysm neck; The intratumoral occlusion unit (1) and the aneurysm neck occlusion unit (2) are respectively mesh structures woven from filaments, and the filaments are made of shape memory material; The intratumoral occlusion unit (1) or the cervical occlusion unit (2) is woven to form a hook part (5), and the intratumoral occlusion unit (1) and the cervical occlusion unit (2) are hooked together through the hook part (5) to form a fixed connection.

2. The aneurysm occlusion system according to claim 1, characterized in that, The intratumoral occlusion unit (1) and the aneurysm neck occlusion unit (2) are fixed outside the body and form an integrated structure, and the integrated structure is implanted into the body through a microcatheter.

3. The aneurysm occlusion system according to claim 1, characterized in that, The connecting part (5) is located in the middle of the neck sealing unit (2).

4. The aneurysm occlusion system according to claim 1, characterized in that, The number of the connecting parts (5) is multiple.

5. The aneurysm occlusion system according to claim 1, characterized in that, The outer surface of the intraneural plugging unit (1) is attached to the aneurysm cavity.

6. The aneurysm occlusion system according to claim 1, characterized in that, After the intra-aneurysmal occlusion unit (1) is implanted into the aneurysm body (3) via a microcatheter and released, the intra-aneurysmal occlusion unit (1) can adapt to the shape of the aneurysm; After the aneurysm neck occlusion unit (2) is implanted into the aneurysm-bearing vessel (4) via a microcatheter and released, the aneurysm neck occlusion unit (2) can adapt to the shape of the aneurysm-bearing vessel (4).

7. The aneurysm occlusion system according to claim 6, characterized in that, The aneurysm neck occlusion unit (2) has a semi-circular curved surface structure inside the aneurysm-bearing vessel (4), and the outer surface of the aneurysm neck occlusion unit (2) is attached to the inner surface of the aneurysm-bearing vessel (4) around the aneurysm.

8. The aneurysm occlusion system according to claim 1, characterized in that, The filaments are made of shape memory alloys, shape memory ceramics, shape memory metal composites, or shape memory polymers.

9. The aneurysm occlusion system according to claim 1, characterized in that, The surface of the intratumoral occlusion unit is coated with a first coating layer, which is used to promote thrombus formation. The surface of the aneurysm neck occlusion unit is coated with a second coating, which is used to promote endothelialization of the aneurysm neck occlusion unit or to prevent thrombosis.

Citation Information

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