A stem cell guided static fixation device based on magnetic targeting technology

By designing a stem cell guided static fixation device based on magnetic targeting technology and utilizing electromagnetic induction coils and multi-axis adjustment structures, the problem of inconvenience in traditional magnetic field adjustment is solved, flexible magnetic field adjustment and precise drug targeting are achieved, and the treatment effect is improved.

CN117122801BActive Publication Date: 2025-09-26INNER MONGOLIA MENGKE STEM CELL GENE MEDICINE RES CO LTD
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Patent Information

Application Number
CN202311175203.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-09-13
Publication Date
2025-09-26
Estimated Expiration
2043-09-13

AI Technical Summary

Technical Problem

The traditional external magnetic field method is difficult to flexibly adjust the magnetic field strength and angle, which affects the effect of stem cell targeted therapy. In particular, the position and size of the electromagnet are not easy to adjust at different lesion locations, resulting in poor treatment effect.

Method used

A stem cell guided static fixation device based on magnetic targeting technology was designed. The electromagnetic induction coil and multi-axis adjustment structure were used to achieve flexible disassembly and assembly, angle and height adjustment of the electromagnetic induction coil. The magnetic field strength was adjusted by current to ensure that the coil was stably aligned with the lesion site.

Benefits of technology

It realizes flexible adjustment and stable alignment of the electromagnetic induction coil, improves the effect of magnetic targeted therapy, adapts to different lesion sites, and ensures the accuracy and therapeutic effect of drug targeting and delivery.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a stem cell guidance static fixation device based on magnetic targeting technology, which relates to the field of targeted therapy. The stem cell guidance static fixation device based on magnetic targeting technology includes a device body, a lifting adjustment seat with lifting and lowering adjustment is provided inside the device body, a supporting frame is provided on the lifting adjustment seat, an adjustable upper and lower azimuth adjustment shaft is provided on the supporting frame, a left and right azimuth adjustment shaft is fixedly connected to the upper and lower azimuth adjustment shaft, and an adjustable adjustment arm is provided on the left and right azimuth adjustment shaft. The stem cell guidance static fixation device based on magnetic targeting technology is convenient for assembling or storing the device as a whole. The electromagnetic induction coil is not only convenient for disassembly and assembly to replace different sizes and models to be suitable for lesions of different sizes, but also the spin angle of the electromagnetic induction coil and the left and right and up and down angles can be flexibly adjusted to ensure that the magnetic targeting positioning of the drug is effective in drug administration.
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Description

Technical Field

[0001] The present invention relates to the technical field of targeted therapy, in particular to a stem cell guided static fixation device based on magnetic targeting technology. Background Art

[0002] With the development of magnetic nanomedicines, applying an external magnetic field to improve the targeting efficiency of magnetic nanomedicines has become an important and safe physical intervention strategy.

[0003] There are two traditional methods of applying an external magnetic field. One is to use a permanent magnet attached to the skin of the patient's lesion site. Although this treatment method is low-cost, it is not easy to control the magnetic strength. The other is to use an electromagnet to be placed at the patient's lesion site, and change the magnetic field strength by the current size to adjust to the magnetic field strength suitable for different drugs. However, the ring formed by this electromagnet is not easy to adjust the position and can only move in the horizontal direction. Different lesion locations require different deflection angles to ensure better magnetic field targeting effect. If there is a deviation in the magnetic field angle, it is easy to affect organs in other normal parts and reduce the efficacy of stem cell targeted therapy. Moreover, the size of the electromagnet itself is not easy to adjust, so the size of the magnetic field cannot be adjusted according to the size of the lesion site, which affects the treatment effect. In response to the shortcomings of the existing technology, the present invention provides a stem cell guided static fixation device based on magnetic targeting technology to solve the above problems. Summary of the Invention

[0004] (1) Technical problems solved

[0005] In response to the shortcomings of the existing technology, the present invention provides a stem cell guidance static fixation device based on magnetic targeting technology, which is convenient for assembling or storing the entire device. After the entire device is assembled, an electromagnetic induction coil is used to provide magnetic targeted stem cell guidance to the patient's lesion site. The electromagnetic induction coil is not only convenient for disassembly and assembly to replace different sizes and models to adapt to lesions of different sizes, but also the rotation angle of the electromagnetic induction coil and the left and right and up and down angles can be flexibly adjusted. The height of the electromagnetic induction coil is also convenient to adjust, so that the electromagnetic induction coil can be conveniently facing the patient's lesion site and the position and angle of the electromagnetic induction coil can be kept stable. The strength of the magnetic field is adjusted by adjusting the current passed into the electromagnetic induction coil, so that the stem cell guidance process of the magnetic targeting technology is stable, ensuring that the magnetic targeting positioning of the drug delivery treatment effect is good.

[0006] (2) Technical solution

[0007] To achieve the above objectives, the present invention is implemented through the following technical solutions: a stem cell guided static fixation device based on magnetic targeting technology, comprising a device body, wherein a lifting and adjusting seat with lifting and adjusting type is provided inside the device body, and a supporting frame is provided on the lifting and adjusting seat;

[0008] The carrier is provided with an adjustable upper and lower position adjustment shaft, and the upper and lower position adjustment shaft is fixedly connected to the left and right position adjustment shaft;

[0009] The left and right azimuth adjustment shaft is provided with an adjustable adjustment arm, and the adjustment arm is provided with an angle adjustment seat;

[0010] The angle adjustment seat and the adjustment arm are provided with a fixed card slot inside, and the fixed card slot is movably connected to a fixed card post inside.

[0011] The fixed clamping column is rotatably connected to a connecting rod, and the connecting rod is provided with an electromagnetic induction coil;

[0012] The angle adjustment seat is provided with an angle adjustment mechanism, and the angle adjustment mechanism is used to adjust the angle of the connecting rod and the electromagnetic induction coil.

[0013] Preferably, the carrier is provided with a first shaft sleeve, and the upper and lower position adjustment shafts are rotatably connected in the first shaft sleeve;

[0014] The adjusting arm is provided with a second shaft sleeve, and the left and right azimuth adjusting shaft is rotatably connected in the second shaft sleeve.

[0015] Preferably, a first gear is provided on the upper and lower position adjustment shafts, a first electric push rod is provided on the carrier frame, a first rack is provided at the output end of the first electric push rod, and the first rack is meshed with the first gear;

[0016] A second gear is provided on the left and right azimuth adjustment shaft, a second electric push rod is provided on the adjustment arm, a second rack is provided at the output end of the second electric push rod, and the second rack is meshed with the second gear.

[0017] Preferably, a first limiting sleeve is provided on the first shaft sleeve, and the first rack is slidably connected in the first limiting sleeve;

[0018] A second limiting sleeve is provided on the second shaft sleeve, and the second rack is slidably connected to the inside of the second limiting sleeve.

[0019] Preferably, the fixed clamping column is provided with a shaft seat, and the connecting rod is rotatably connected in the shaft seat.

[0020] Preferably, a locking hole is provided on the fixed clamping column, a locking seat is fixedly connected to the adjusting arm, an adjustable slider is provided inside the locking seat, a locking rod is provided on the slider, and the locking rod is movably inserted into the locking hole.

[0021] Preferably, a spring is fixedly connected between the slider and the inner cavity of the locking seat, and an unlocking handle is provided on the slider.

[0022] Preferably, the angle adjustment seat is provided with an axle seat slot, the axle seat is movably clamped inside the axle seat slot, the angle adjustment mechanism includes a second screw rod, the second screw rod is threadedly connected to the angle adjustment seat, an arc-shaped clamping positioning block is rotatably connected to the second screw rod, the arc-shaped clamping positioning block is slidably connected to the inside of the angle adjustment seat, the arc-shaped clamping positioning block is clamped to the surface of the connecting rod, and a rotating handle is provided on the second screw rod.

[0023] Preferably, a base is provided on the top of the device body, a universal wheel is provided on the bottom of the base, a push handle is provided on the device body, a storage bin is provided inside the device body, a sealed door is provided on the device body, and an ultraviolet sterilization lamp is provided inside the storage bin.

[0024] Preferably, a guide rail rod is provided inside the device body, the lifting adjustment seat is slidably connected to the guide rail rod, the first screw rod is rotatably connected inside the device body, the first screw rod is threadedly connected to the lifting adjustment seat, a motor body is provided on the top of the device body, the first screw rod is fixedly connected to the output end of the motor body, a first mounting plate is provided on the lifting adjustment seat, a second mounting plate is provided on the supporting frame, and the second mounting plate is fixed to the first mounting plate by bolts.

[0025] The present invention discloses a stem cell guided static fixation device based on magnetic targeting technology, which has the following beneficial effects:

[0026] 1. This stem cell guidance static fixation device based on magnetic targeting technology is convenient for assembling or storing the entire device. After the entire device is assembled, the electromagnetic induction coil is used to provide magnetic targeted stem cell guidance to the patient's lesion site. The electromagnetic induction coil is not only convenient for disassembly and assembly to replace different sizes to suit lesions of different sizes, but also the electromagnetic induction coil's rotation angle and left and right and up and down angles can be flexibly adjusted. The height of the electromagnetic induction coil is also convenient to adjust, so that the electromagnetic induction coil can be conveniently facing the patient's lesion site and keep the position and angle of the electromagnetic induction coil stable. The strength of the magnetic field is adjusted by adjusting the current passed into the electromagnetic induction coil, thereby making the stem cell guidance process of the magnetic targeting technology stable and ensuring good drug magnetic targeting and positioning therapeutic effects.

[0027] 2. The stem cell guided static fixation device based on magnetic targeting technology is easy to assemble and store as a whole. When storing the device as a whole, the supporting frame and the lifting adjustment seat are disassembled, the fixed clamping column and the angle adjustment seat are disassembled, and then the supporting frame, upper and lower position adjustment shafts, left and right position adjustment shafts, adjustment arms, angle adjustment seats, fixed clamping columns, connecting rods and electromagnetic induction coils are placed as a whole inside the storage bin for storage. At the same time, they are disinfected and sterilized by ultraviolet sterilization lamps to ensure the hygiene of the device.

[0028] 3. The stem cell guided static fixation device based on magnetic targeting technology has a locking seat that provides a limit for the slider, and the slider provides support and limit for the locking rod. When the locking rod is inserted into the locking hole, the fixed clamping column is clamped in the fixed clamping slot for locking. Therefore, the installation of the fixed clamping column, the connecting rod and the electromagnetic induction coil is convenient, and the subsequent disassembly and replacement are also convenient, so it is convenient to replace the size of the electromagnetic induction coil. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0030] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0031] Figure 2 This is a structural diagram of the lifting and adjusting seat of the present invention;

[0032] Figure 3 This is a schematic structural diagram of the storage bin of the present invention;

[0033] Figure 4 Schematic diagram of the overall connection between the carrier and the electromagnetic induction coil of the present invention;

[0034] Figure 5 This is a schematic diagram of the connection of the upper and lower azimuth adjustment shafts of the present invention;

[0035] Figure 6 This is a schematic diagram of the connection of the left and right azimuth adjustment shafts of the present invention;

[0036] Figure 7 It is a cross-sectional schematic diagram of the locking seat of the present invention;

[0037] Figure 8 It is a cross-sectional schematic diagram of the angle adjustment seat of the present invention;

[0038] Figure 9It is a structural schematic diagram of the electromagnetic induction coil of the present invention.

[0039] In the figure: 1. Device body; 101. Base; 102. Universal wheel; 103. Push handle; 104. Storage compartment; 105. Sealed door; 106. UV germicidal lamp; 2. Lifting adjustment seat; 201. Guide rod; 202. First screw rod; 203. Motor body; 204. First mounting plate; 3. Carrying frame; 301. Second mounting plate; 302. First shaft sleeve; 303. First limiting sleeve; 4. Up and down azimuth adjustment shaft; 401. First gear; 402. First electric push rod; 403. First rack; 5. Left and right azimuth adjustment shaft; 50 1. Second gear; 502. Second electric push rod; 503. Second rack; 6. Adjusting arm; 601. Second sleeve; 602. Second limiting sleeve; 7. Angle adjustment seat; 701. Fixed slot; 702. Shaft seat slot; 703. Second screw rod; 704. Arc clamping positioning block; 705. Rotating handle; 8. Fixed clamping column; 801. Locking hole; 802. Shaft seat; 9. Connecting rod; 10. Electromagnetic induction coil; 11. Locking seat; 1101. Slider; 1102. Locking rod; 1103. Spring; 1104. Unlocking handle. DETAILED DESCRIPTION

[0040] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention are clearly and completely described. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0041] The embodiment of the present application provides a stem cell guiding static fixation device based on magnetic targeting technology, which solves the problem that when the traditional external magnetic field method in magnetic targeting technology uses an electromagnetic method, the ring formed by the electromagnet is not easy to adjust the position and can only move in the horizontal direction. Different lesion locations require different deflection angles to ensure better magnetic field targeting effect. If there is a deviation in the magnetic field angle, it is easy to affect organs in other normal parts and reduce the efficacy of stem cell targeted therapy. In addition, the size of the electromagnet itself is not easy to adjust, so the size of the magnetic field cannot be adjusted according to the size of the lesion site, which affects the treatment effect.

[0042] In order to better understand the above technical solution, the above technical solution will be described in detail below with reference to the accompanying drawings and specific implementation methods.

[0043] The embodiment of the present invention discloses a stem cell guided static fixation device based on magnetic targeting technology. Figure 1-9As shown, it includes a device body 1, an interior of the device body 1 is provided with a lifting adjustment seat 2 of lifting adjustment type, and a supporting frame 3 is provided on the lifting adjustment seat 2;

[0044] The carrier 3 is provided with an adjustable upper and lower position adjustment shaft 4, and the upper and lower position adjustment shaft 4 is fixedly connected to the left and right position adjustment shaft 5;

[0045] An adjustable adjustment arm 6 is provided on the left and right azimuth adjustment shaft 5, and an angle adjustment seat 7 is provided on the adjustment arm 6;

[0046] A fixed card slot 701 is provided inside the angle adjustment seat 7 and the adjustment arm 6, and a fixed card post 8 is movably connected inside the fixed card slot 701;

[0047] A connecting rod 9 is rotatably connected to the fixed clamping column 8, and an electromagnetic induction coil 10 is provided on the connecting rod 9;

[0048] An angle adjustment mechanism is provided on the angle adjustment seat 7 , and the angle adjustment mechanism is used to adjust the angle of the connecting rod 9 and the electromagnetic induction coil 10 .

[0049] Specifically, a first shaft sleeve 302 is provided on the carrier 3, and the upper and lower position adjustment shafts 4 are rotatably connected in the first shaft sleeve 302;

[0050] A second sleeve 601 is provided on the adjusting arm 6, and the left and right azimuth adjusting shaft 5 is rotatably connected in the second sleeve 601. The first sleeve 302 is provided to provide support and limitation for the upper and lower azimuth adjusting shafts 4, and the second sleeve 601 is provided to provide support and limitation for the left and right azimuth adjusting shafts 5.

[0051] Furthermore, a first gear 401 is provided on the upper and lower position adjustment shafts 4, a first electric push rod 402 is provided on the carrier 3, and a first rack 403 is provided at the output end of the first electric push rod 402, and the first rack 403 is meshed with the first gear 401;

[0052] A second gear 501 is provided on the left and right azimuth adjustment shaft 5, a second electric push rod 502 is provided on the adjustment arm 6, a second rack 503 is provided at the output end of the second electric push rod 502, the second rack 503 is engaged with the second gear 501, and the first electric push rod 402 is provided to conveniently drive the first rack 403 to move and make the first gear 401 rotate, thereby realizing the rotation of the upper and lower azimuth adjustment shaft 4 and realizing the upper and lower azimuth adjustment of the electromagnetic induction coil 10. The second electric push rod 502 is provided to conveniently drive the second rack 503 to move and move relative to the second gear 501, so that the electromagnetic induction coil 10 can be adjusted to the left and right azimuth.

[0053] Furthermore, a first limiting sleeve 303 is provided on the first shaft sleeve 302, and the first rack 403 is slidably connected in the first limiting sleeve 303;

[0054] A second limiting sleeve 602 is provided on the second shaft sleeve 601, and the second rack 503 is slidably connected to the inside of the second limiting sleeve 602. The first limiting sleeve 303 is provided to provide support and limitation for the first rack 403, and the second limiting sleeve 602 is provided to provide support and limitation for the second rack 503, ensuring the stable force of the first rack 403 and the second rack 503.

[0055] Specifically, a shaft seat 802 is provided on the fixed clamping column 8, and the connecting rod 9 is rotatably connected in the shaft seat 802. The provided shaft seat 802 realizes the rotational connection between the fixed clamping column 8 and the connecting rod 9, ensuring the stability of the connection.

[0056] Furthermore, a locking hole 801 is provided on the fixed clamping column 8, and a locking seat 11 is fixedly connected to the adjusting arm 6. An adjustable slider 1101 is provided inside the locking seat 11, and a locking rod 1102 is provided on the slider 1101. The locking rod 1102 is movably inserted into the locking hole 801. The provided locking seat 11 provides a limit for the slider 1101, and the provided slider 1101 provides support and limit for the locking rod 1102. When the locking rod 1102 is inserted into the locking hole 801, the fixed clamping column 8 is locked in the fixed slot 701 for locking. Therefore, the installation of the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10 is convenient, and the subsequent disassembly and replacement is also convenient, so it is convenient to replace the size of the electromagnetic induction coil 10.

[0057] Furthermore, a spring 1103 is fixedly connected between the slider 1101 and the inner cavity of the locking seat 11, and an unlocking handle 1104 is provided on the slider 1101. The provided spring 1103 applies elastic force to the slider 1101 and the locking rod 1102 as a whole, so that the locking rod 1102 is stable and not easy to loosen when inserted into the locking hole 801. The provided unlocking handle 1104 facilitates the pushing of the slider 1101 and the locking rod 1102 as a whole.

[0058] Specifically, an axle seat slot 702 is provided on the angle adjustment seat 7, and the axle seat 802 is movably connected to the inside of the axle seat slot 702. The angle adjustment mechanism includes a second screw rod 703, and the second screw rod 703 is threadedly connected to the angle adjustment seat 7. An arc-shaped clamping positioning block 704 is rotatably connected to the second screw rod 703, and the arc-shaped clamping positioning block 704 is slidably connected to the inside of the angle adjustment seat 7. The arc-shaped clamping positioning block 704 is clamped with the surface of the connecting rod 9, and a rotating handle 705 is provided on the second screw rod 703. The overall structure of the angle adjustment mechanism is simple, and the arc-shaped clamping positioning block 704 is clamped with the surface of the connecting rod 9 to achieve the clamping and fixing of the rotation angle of the connecting rod 9.

[0059] Specifically disclosed is that a base 101 is provided on the top of the device body 1, a universal wheel 102 is provided at the bottom of the base 101, a push handle 103 is provided on the device body 1, a storage bin 104 is provided inside the device body 1, a sealed door 105 is provided on the device body 1, and an ultraviolet sterilization lamp 106 is provided inside the storage bin 104. The provided base 101, universal wheel 102 and push handle 103 make the device as a whole convenient to move, the provided storage bin 104 is convenient for storing multiple groups of electromagnetic induction coils 10 of different models and disassembled carrier frames 3, upper and lower azimuth adjustment shafts 4, left and right azimuth adjustment shafts 5, adjustment arms 6 and angle adjustment seats 7, the provided sealed door 105 is convenient for protecting the storage bin 104, and the provided ultraviolet sterilization lamp 106 is convenient for disinfecting and sterilizing the interior of the storage bin 104.

[0060] Furthermore, a guide rod 201 is provided inside the device body 1, and the lifting adjustment seat 2 is slidably connected to the guide rod 201. The first screw rod 202 is rotatably connected to the lifting adjustment seat 2 inside the device body 1, and the first screw rod 202 is threadedly connected to the lifting adjustment seat 2. A motor body 203 is provided on the top of the device body 1, and the first screw rod 202 is fixedly connected to the output end of the motor body 203. A first mounting plate 204 is provided on the lifting adjustment seat 2, and a second mounting plate 301 is provided on the supporting frame 3. The second mounting plate 301 is fixed to the first mounting plate 204 by bolts. The second mounting plate 301 and the first mounting plate 204 are convenient for disassembly and assembly of the lifting adjustment seat 2 and the supporting frame 3. The lifting adjustment seat 2, guide rod 201, first screw rod 202 and motor body 203 are convenient for height adjustment of the lifting adjustment seat 2, thereby making it convenient to adjust the height of the supporting frame 3, the upper and lower azimuth adjustment shafts 4, the left and right azimuth adjustment shafts 5, the adjusting arm 6, the angle adjustment seat 7, the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10.

[0061] Working Principle: This stem cell guided static fixation device based on magnetic targeting technology is easy to assemble and store as a whole. When storing the device as a whole, the carrier frame 3 and the lifting adjustment seat 2 are disassembled, the fixed clamping column 8 and the angle adjustment seat 7 are disassembled, and then the carrier frame 3, the upper and lower position adjustment shaft 4, the left and right position adjustment shaft 5, the adjustment arm 6, the angle adjustment seat 7, the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10 are placed in the storage compartment 104 for storage. At the same time, the device is disinfected and sterilized by the ultraviolet germicidal lamp 106 to ensure the hygiene of the device.

[0062] During use, the device is easy to assemble quickly, and the height and XYZ axis deflection angle of the electromagnetic induction coil 10 can be adjusted and fixed in position at the same time, thereby achieving the goal of using the induced magnetic field generated by the electromagnetic induction coil 10 to face the lesion site while maintaining the position and angle of the electromagnetic induction coil 10 stable. The intensity of the magnetic field is adjusted by adjusting the current flowing into the electromagnetic induction coil 10, thereby stabilizing the stem cell guidance process of the magnetic targeting technology and ensuring good magnetic targeting drug delivery treatment effects.

[0063] When assembling the entire device, first fix the first mounting plate 204 and the second mounting plate 301 with bolts, then insert the fixed clamping column 8 into the fixed clamping slot 701, and pull the unlocking handle 1104 upwards at the same time, so that the unlocking handle 1104 drives the slider 1101 and the locking rod 1102 to move upwards and squeeze the spring 1103 at the same time. When the fixed clamping column 8 is fully inserted into the fixed clamping slot 701, release the unlocking handle 1104, and use the restoring elastic force of the spring 1103 to push the slider 1101 and the locking rod 1102 to move, so that the locking rod 1102 is inserted into the locking hole 801, thereby fixing the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10 on the adjusting arm 6 and the angle adjustment seat 7;

[0064] Furthermore, the rotation angle of the electromagnetic induction coil 10 is adjusted so that the electromagnetic induction coil 10 is facing the patient's lesion. After the adjustment is completed, the rotation handle 705 is rotated to drive the second screw rod 703 to rotate, and the second screw rod 703 is used to push the arc-shaped clamping and positioning block 704 to move and clamp the arc-shaped clamping and positioning block 704 to limit the connecting rod 9, thereby achieving a fixed angle between the connecting rod 9 and the electromagnetic induction coil 10.

[0065] Furthermore, the height of the electromagnetic induction coil 10 is adjusted by driving the motor body 203, which drives the first screw rod 202 to rotate, and the first screw rod 202 drives the lifting adjustment seat 2 to move, and the lifting adjustment seat 2 drives the supporting frame 3, the upper and lower position adjustment shaft 4, the left and right position adjustment shaft 5, the adjustment arm 6, the angle adjustment seat 7, the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10 to move up and down as a whole, thereby achieving the height adjustment of the electromagnetic induction coil 10;

[0066] When adjusting the left and right and up and down inclination angles of the height of the electromagnetic induction coil 10, the first electric push rod 402 and the second electric push rod 502 are used. When the first electric push rod 402 is working, it drives the first rack 403 to move, and the first rack 403 drives the first gear 401 to rotate. The first gear 401 drives the upper and lower position adjustment shafts 4 to rotate, and the upper and lower position adjustment shafts 4 drive the left and right position adjustment shafts 5, the adjustment arm 6, the angle adjustment seat 7, the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10 to rotate as a whole, thereby achieving the up and down angle adjustment of the electromagnetic induction coil 10;

[0067] When the second electric push rod 502 is working, it drives the second rack 503 to move relative to the second gear 501, so that the adjustment arm 6 rotates along the left and right azimuth adjustment axis 5. Then, the adjustment arm 6 drives the angle adjustment seat 7, the fixed clamping column 8, the connecting rod 9 and the electromagnetic induction coil 10 to rotate as a whole, thereby achieving left and right angle adjustment of the electromagnetic induction coil 10;

[0068] In summary, the stem cell guidance static fixation device based on magnetic targeting technology is convenient for assembling or storing the entire device. After the entire device is assembled, the electromagnetic induction coil 10 is used to provide magnetic targeted stem cell guidance to the patient's lesion site. The electromagnetic induction coil 10 is not only convenient for disassembly and assembly to replace different sizes to suit lesions of different sizes, but also the rotation angle of the electromagnetic induction coil 10 and the left and right and up and down angles can be flexibly adjusted. The height of the electromagnetic induction coil 10 is also convenient to adjust, so that the electromagnetic induction coil 10 is convenient to face the patient's lesion site and keep the position and angle of the electromagnetic induction coil 10 stable. The strength of the magnetic field is adjusted by adjusting the current passed into the electromagnetic induction coil 10, so that the stem cell guidance process of the magnetic targeting technology is stable, ensuring that the magnetic targeting positioning drug delivery treatment effect is good.

[0069] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, an element defined by the phrase "comprising a ..." does not exclude the presence of other identical elements in the process, method, article, or device comprising the element.

[0070] The basic principles, main features, and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and modifications may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and modifications are intended to fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. A stem cell guided static fixation device based on magnetic targeting technology, comprising a device body (1), characterized in that: A lifting and adjusting seat (2) of lifting and adjusting type is provided inside the device body (1), and a supporting frame (3) is provided on the lifting and adjusting seat (2); The carrier frame (3) is provided with an adjustable upper and lower azimuth adjustment shaft (4), and the upper and lower azimuth adjustment shaft (4) is fixedly connected to a left and right azimuth adjustment shaft (5); An adjustable adjustment arm (6) is provided on the left and right azimuth adjustment shaft (5), and an angle adjustment seat (7) is provided on the adjustment arm (6); A fixed card slot (701) is provided inside the angle adjustment seat (7) and the adjustment arm (6), and a fixed card post (8) is movably connected inside the fixed card slot (701); A connecting rod (9) is rotatably connected to the fixed clamping column (8), and an electromagnetic induction coil (10) is provided on the connecting rod (9); The angle adjustment seat (7) is provided with an angle adjustment mechanism, and the angle adjustment mechanism is used to adjust the angle of the connecting rod (9) and the electromagnetic induction coil (10); The carrier frame (3) is provided with a first shaft sleeve (302), and the upper and lower position adjustment shafts (4) are rotatably connected in the first shaft sleeve (302); The regulating arm (6) is provided with a second shaft sleeve (601), and the left and right azimuth regulating shaft (5) is rotatably connected in the second shaft sleeve (601); A first gear (401) is provided on the upper and lower position adjustment shaft (4), a first electric push rod (402) is provided on the carrier frame (3), a first rack (403) is provided at the output end of the first electric push rod (402), and the first rack (403) is meshed with the first gear (401); A second gear (501) is provided on the left-right azimuth adjustment shaft (5), a second electric push rod (502) is provided on the adjustment arm (6), a second rack (503) is provided at the output end of the second electric push rod (502), and the second rack (503) is meshed with the second gear (501); The fixed clamping column (8) is provided with a shaft seat (802), and the connecting rod (9) is rotatably connected in the shaft seat (802); The angle adjustment seat (7) is provided with an axle seat slot (702), and the axle seat (802) is movably connected to the inside of the axle seat slot (702). The angle adjustment mechanism includes a second screw rod (703), the second screw rod (703) is threadedly connected to the angle adjustment seat (7), and an arc-shaped clamping positioning block (704) is rotatably connected to the second screw rod (703). The arc-shaped clamping positioning block (704) is slidably connected to the inside of the angle adjustment seat (7), and the arc-shaped clamping positioning block (704) is clamped to the surface of the connecting rod (9). The second screw rod (703) is provided with a rotating handle (705).

2. The stem cell guided static fixation device based on magnetic targeting technology according to claim 1, characterized in that: A first limiting sleeve (303) is provided on the first shaft sleeve (302), and the first rack (403) is slidably connected in the first limiting sleeve (303); A second limiting sleeve (602) is provided on the second shaft sleeve (601), and the second rack (503) is slidably connected to the interior of the second limiting sleeve (602).

3. The stem cell guided static fixation device based on magnetic targeting technology according to claim 1, characterized in that: A locking hole (801) is provided on the fixed clamping column (8), a locking seat (11) is fixedly connected to the adjusting arm (6), an adjustable slider (1101) is provided inside the locking seat (111), a locking rod (1102) is provided on the slider (1101), and the locking rod (1102) is movably inserted into the locking hole (801).

4. The stem cell guided static fixation device based on magnetic targeting technology according to claim 3, characterized in that: A spring (1103) is fixedly connected between the slider (1101) and the inner cavity of the locking seat (11), and an unlocking handle (1104) is provided on the slider (1101).

5. The stem cell guided static fixation device based on magnetic targeting technology according to claim 1, characterized in that: The top of the device body (1) is provided with a base (101), the bottom of the base (101) is provided with a universal wheel (102), the device body (1) is provided with a push handle (103), the interior of the device body (1) is provided with a storage bin (104), the device body (1) is provided with a sealing door (105), and the interior of the storage bin (104) is provided with an ultraviolet sterilization lamp (106).

6. The stem cell guided static fixation device based on magnetic targeting technology according to claim 1, characterized in that: A guide rail rod (201) is provided inside the device body (1), the lifting adjustment seat (2) is slidably connected to the guide rail rod (201), a first screw rod (202) is rotatably connected inside the device body (1), the first screw rod (202) is threadedly connected to the lifting adjustment seat (2), a motor body (203) is provided on the top of the device body (1), the first screw rod (202) is fixedly connected to the output end of the motor body (203), a first mounting plate (204) is provided on the lifting adjustment seat (2), a second mounting plate (301) is provided on the supporting frame (3), and the second mounting plate (301) is fixed to the first mounting plate (204) by bolts.

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