A multi-plane based heart valve determination method, device and electronic equipment

Abstract

The application discloses a kind of based on multi-plane cardiac valve determination method, device and electronic equipment.Therein, the method comprises: according to the anatomical structure image of heart, determine multiple target planes in heart;Determine the first initial push point in each target plane in multiple target planes;Determine the first push open arrival point corresponding to the first initial push point, wherein the position where the first push open arrival point is located is the position reached after the first initial push point moves to the pipe wall by first push open distance, and the pipe wall is the pipe wall of aortic sinus in heart;According to the first push open arrival point, determine the first push open range corresponding to each target plane;According to the first push open range corresponding to each target plane, determine the second push open range corresponding to autologous heart valve;According to the second push open range, determine the artificial heart valve matched with autologous heart valve.The application solves the technical problem that accuracy cannot be guaranteed due to the determination of heart valve according to experience in the related art.

Description

Technical Field

[0001] This invention relates to the field of medical technology, and more specifically, to a method, apparatus, and electronic device for determining heart valves based on a multi-plane approach. Background Technology

[0002] The aortic valve is located in the opening between the left ventricle and the ascending aorta, and it opens with the contraction of the left ventricle. A normal aortic valve consists of three semilunar leaflets, through which blood flows through the aortic valve and into the ascending aorta to supply the whole body. When the aortic valve leaflets are congenitally malformed or undergo degenerative calcification, the leaflets thicken, calcify, or fuse, narrowing the valve opening and reducing the amount of blood pumped into the aorta, affecting normal cardiac function, and in more severe cases, leading to heart failure.

[0003] For patients with severe aortic stenosis, surgical replacement of the diseased valve is the best treatment option. Traditional surgical replacement methods are highly invasive and have a long recovery period; therefore, an increasing number of patients are now undergoing transcatheter aortic valve replacement (TAVR). During TAVR surgery, it is necessary to select an artificial heart valve suitable for the patient's specific physiological and anatomical structure, i.e., to choose the appropriate artificial heart valve model.

[0004] When determining the type of artificial heart valve, the extent to which the patient's heart valves are displaced is an important reference parameter. Currently, there is no standard procedure for determining the extent to which a patient's heart valves are displaced during TAVR surgery. In many cases, it depends on the doctor's experience, which leads to a longer time required to determine the extent to which the heart valves are displaced and the accuracy cannot be guaranteed. Summary of the Invention

[0005] This invention provides a method, apparatus, and electronic device for determining heart valves based on multiple planes, to at least solve the technical problem that the accuracy of heart valve determination based on experience in related technologies cannot be guaranteed.

[0006] According to one aspect of the present invention, a method for determining an artificial heart valve based on multiple planes is provided, comprising: determining multiple target planes in the heart based on an anatomical image of the heart; determining a first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of an autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance toward the aortic sinus in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; and determining an artificial heart valve matching the autologous heart valve based on the second push-off range.

[0007] Optionally, determining multiple target planes in the heart based on anatomical images includes: determining the position of a reference plane in the heart based on anatomical images; and selecting multiple cross-sections above the reference plane, wherein the multiple cross-sections are the multiple target planes.

[0008] Optionally, the reference plane is the plane defined by the lowest point of the wall of the aortic sinus where the leaflet of the autologous heart valve is attached.

[0009] Optionally, based on the first push-away point, the first push-away range corresponding to each target plane is determined as follows:

[0010] Based on the first push-opening arrival point, the target shape is determined, wherein all the first push-opening arrival points are located on the outline of the target shape; the size information of the target shape is determined, and the first push-opening range is determined based on the size information.

[0011] Optionally, determining the target shape based on the first push-opening point includes: determining the structural features of the autologous heart valve in each target plane, wherein the structural features of the autologous heart valve include the fusion between any two adjacent leaflets of the autologous heart valve; determining a second push-opening point in each target plane based on the structural features of the autologous heart valve, wherein the second push-opening point is located at the boundary edge of any two adjacent leaflets; and determining the target shape based on the first push-opening point and the second push-opening point, wherein all second push-opening points are located on the outline of the target shape.

[0012] Optionally, determining the second push-off arrival point in each target plane based on the structural characteristics of the autologous heart valve includes: determining the junction of any two adjacent leaflets as the second push-off arrival point corresponding to the two adjacent leaflets when no fusion occurs between them; determining the second initial push point at the junction of any two adjacent leaflets when fusion occurs between them; and determining the second push-off arrival point based on the second initial push point.

[0013] Optionally, determining the second push-off arrival point based on the second initial push point includes: determining the fusion status between any two adjacent leaflets, wherein the fusion status includes at least one of the following: fusion type, fusion portion length; determining the second push-off distance corresponding to the second initial push point based on the fusion status; and determining the second push-off arrival point based on the second push-off distance and the second initial push point, wherein the position of the second push-off arrival point is the position reached after the second initial push point moves along the fusion site in a direction away from the center of the autologous heart valve by the second push-off distance.

[0014] Optionally, determining the second push-opening range corresponding to the autologous heart valve based on the first push-opening range corresponding to each target plane includes: determining the smallest first push-opening range among multiple first push-opening ranges as the second push-opening range.

[0015] Optionally, determining the first push-opening arrival point corresponding to the first initial push point includes: determining the thickness and calcification degree of the leaflet corresponding to the first initial push point; determining the first push-opening distance based on the thickness and calcification degree of the leaflet; and determining the position of the first push-opening arrival point based on the position of the first initial push point and the first push-opening distance.

[0016] According to another aspect of the present invention, a method for determining an artificial heart valve based on multiple planes is also provided, comprising: acquiring an anatomical image of the heart; determining multiple target planes in the heart based on the anatomical image of the heart; determining a first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of an autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance toward the wall, and the wall is the wall of the aortic sinus in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; determining target setting parameters corresponding to the artificial heart valve based on the second push-off range, wherein the target setting parameters include the size information of the artificial heart valve; and determining the artificial heart valve based on the target setting parameters.

[0017] Optionally, the target plane is a plane located above the aortic valve annulus. The determination of the corresponding target setting parameters of the artificial heart valve based on the second opening range includes: determining the first structural feature of the aortic valve annulus and the second structural feature of the autologous heart valve below the aortic valve annulus; and determining the target setting parameters based on the first structural feature, the second structural feature, and the second opening range.

[0018] According to another aspect of the present invention, an apparatus for determining an artificial heart valve is provided, comprising: a processing module for determining a plurality of target planes in the heart based on an anatomical image of the heart; an identification module for determining a first initial push point in each of the plurality of target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of an autologous heart valve; a positioning module for determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance toward the wall, and the wall is the wall of the aortic sinus in the heart; a calculation module for determining a first push-off range corresponding to each target plane based on the first push-off arrival point; a selection module for determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; and a determination module for determining an artificial heart valve matching the autologous heart valve based on the second push-off range.

[0019] According to another aspect of the present invention, a non-volatile storage medium is provided, the non-volatile storage medium including a stored program, wherein, when the program is running, the device where the non-volatile storage medium is located executes a multi-plane-based artificial heart valve determination method.

[0020] According to another aspect of the present invention, an electronic device is provided, the electronic device including a processor for running a program, wherein the program executes a multiplane-based artificial heart valve determination method during runtime.

[0021] In this embodiment of the invention, multiple target planes are determined within the heart based on anatomical images of the heart; a first initial push point is determined within each target plane, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve; a first push-off arrival point is determined corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance towards the aortic sinus wall in the heart; a first push-off range is determined for each target plane based on the first push-off arrival point; and the autologous heart valve is then determined based on the first push-off range corresponding to each target plane. The second retraction range corresponding to the visceral valve; based on the second retraction range, the method of determining the artificial heart valve matching the autologous heart valve is achieved by determining multiple target planes in the autologous heart valve and determining the initial push point and push arrival point in each target plane, thereby determining the first retraction range corresponding to each target plane, and further determining the second retraction range of the autologous heart valve based on the first retraction range corresponding to each target plane. This achieves the technical effect of determining the artificial heart valve matching the autologous heart valve based on the second retraction range, and solves the technical problem of inaccuracy caused by determining the heart valve based on experience in related technologies. Attached Figure Description

[0022] The accompanying drawings, which are included to provide a further understanding of the invention and form part of this application, illustrate exemplary embodiments of the invention and, together with their description, serve to explain the invention and do not constitute an undue limitation thereof. In the drawings:

[0023] Figure 1 This is a schematic flowchart of a method for determining an artificial heart valve based on a multi-plane configuration according to an embodiment of the present disclosure.

[0024] Figure 2 This is a schematic longitudinal section of an autologous heart valve according to an embodiment of the present disclosure;

[0025] Figure 3 This is a schematic flowchart of a heart valve determination process according to an embodiment of the present disclosure;

[0026] Figure 4 This is a schematic flowchart of another heart valve determination process according to an embodiment of the present disclosure;

[0027] Figure 5 This is a schematic flowchart of another method for determining an artificial heart valve based on a multi-plane configuration according to an embodiment of the present disclosure;

[0028] Figure 6a This is a cross-sectional schematic diagram of a first type of autologous heart valve according to an embodiment of the present disclosure;

[0029] Figure 6b This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the first type of autologous heart valve according to the embodiments of this disclosure;

[0030] Figure 6c This is a schematic diagram of the opening range corresponding to the first type of autologous heart valve according to an embodiment of the present disclosure;

[0031] Figure 7a This is a cross-sectional schematic diagram of a second type of autologous heart valve according to an embodiment of the present disclosure;

[0032] Figure 7b This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the second type of autologous heart valve according to an embodiment of the present disclosure;

[0033] Figure 7c This is a schematic diagram of the opening range corresponding to the second type of autologous heart valve according to an embodiment of the present disclosure;

[0034] Figure 8a This is a cross-sectional schematic diagram of a third type of autologous heart valve according to an embodiment of the present disclosure;

[0035] Figure 8b This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the third type of autologous heart valve according to the embodiments of this disclosure;

[0036] Figure 8c This is a schematic diagram of the opening range corresponding to the third type of autologous heart valve according to an embodiment of the present disclosure;

[0037] Figure 9a This is a cross-sectional schematic diagram of a fourth type of autologous heart valve according to an embodiment of the present disclosure;

[0038] Figure 9b This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the fourth type of autologous heart valve according to the embodiments of this disclosure;

[0039] Figure 9c This is a schematic diagram of the opening range corresponding to the fourth type of autologous heart valve according to an embodiment of the present disclosure;

[0040] Figure 10a This is a cross-sectional schematic diagram of a fifth type of autologous heart valve according to an embodiment of the present disclosure;

[0041] Figure 10b This is a schematic diagram of the initial push point and the push-out arrival point of a type 5 autologous heart valve according to an embodiment of the present disclosure;

[0042] Figure 10c This is a schematic diagram of the opening range corresponding to a type 5 autologous heart valve according to an embodiment of this disclosure;

[0043] Figure 10d This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the second type of fifth-class autologous heart valve according to the embodiments of this disclosure;

[0044] Figure 10e This is a schematic diagram of the opening range corresponding to the second type of fifth-class autologous heart valve according to the embodiments of this disclosure;

[0045] Figure 10f This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the third type of fifth type autologous heart valve according to the embodiments of this disclosure;

[0046] Figure 10g This is a schematic diagram of the opening range corresponding to the third type of fifth-class autologous heart valve according to the embodiments of this disclosure;

[0047] Figure 10h This is a schematic diagram of the initial push point and the push-out arrival point corresponding to the fourth type of fifth type autologous heart valve according to the embodiments of this disclosure;

[0048] Figure 10i This is a schematic diagram of the opening range corresponding to the fourth type of fifth-class autologous heart valve according to the embodiments of this disclosure;

[0049] Figure 11 This is a schematic diagram of a multi-plane artificial heart valve determination device according to an embodiment of the present disclosure;

[0050] Figure 12 This is a schematic diagram of the structure of a computer device according to an embodiment of the present disclosure. Detailed Implementation

[0051] To enable those skilled in the art to better understand the present invention, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of the present invention.

[0052] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this invention are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged where appropriate so that the embodiments of the invention described herein can be implemented in orders other than those illustrated or described herein. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover a non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0053] First, some nouns or terms that appear in the description of the embodiments of this disclosure shall be interpreted as follows:

[0054] Normal aortic structure: The aortic valve is located in the opening between the left ventricle and the ascending aorta. It opens with the contraction of the left ventricle to pump blood into the aorta, which then supplies blood to the whole body. A normal aortic valve consists of three semilunar leaflets. The leaflets attach to the proximal end of the aortic valve, and the aortic wall bulges outward to form the aortic sinuses, which are divided into the left coronary sinus, right coronary sinus, and non-coronary sinus according to their respective coronary artery openings. Each leaflet attaches to the aortic wall at its base with a semicircular margin, and any two adjacent leaflets intersect at their junctional edges.

[0055] Aortic stenosis (AS) is a condition where the opening of the aortic valve in the heart becomes narrowed, preventing it from opening completely. Aortic stenosis causes thickening and narrowing of the valve between the heart's main pump chamber (left ventricle) and the body's main artery (aorta). This narrowing reduces or prevents blood from flowing from the heart to other parts of the body. Aortic stenosis is usually caused by congenital valve leaflet malformations (bi-leaflet, quad-leaflet, uni-leaflet) or degenerative valve calcification, primarily manifested as leaflet calcification, leaflet thickening, and fusion at the leaflet junction.

[0056] Leaflet fusion: This occurs when the junctional edges of two adjacent leaflets adhere together, sometimes with calcification and sometimes without. The edges of the two leaflets fuse completely or partially together, preventing them from fully opening and thus reducing the leaflet opening. Based on the fusion pattern, it can be classified into three types: complete calcification fusion, partial calcification fusion, and non-calcification fusion. Non-calcification fusion refers to the adhesion of two adjacent leaflets without any calcification.

[0057] Inner side of the leaflet: During ventricular systole, when the leaflet is fully open, the side of the leaflet closest to the central axis of the aorta.

[0058] Lateral leaflet: During ventricular systole, when the leaflets are fully open, the side of the leaflet that is relatively far from the central axis of the aorta.

[0059] Leaflet thickness: The height of a cross-section on the same leaflet, the distance from the outer side of the leaflet to the inner side of the leaflet.

[0060] Reference plane: The plane corresponding to the aortic valve annulus, specifically the plane determined by the attachment of the aortic valve leaflet to the lowest point of the vessel wall, usually referring to the plane corresponding to the virtual valve annulus.

[0061] According to an embodiment of the present invention, a method embodiment for determining an artificial heart valve based on a multi-plane approach is provided. It should be noted that the steps shown in the flowchart in the accompanying drawings can be executed in a computer system such as a set of computer-executable instructions. Furthermore, although a logical order is shown in the flowchart, in some cases, the steps shown or described may be executed in a different order than that shown here.

[0062] Figure 1 This is a method for determining artificial heart valves based on multiplanar planes according to embodiments of the present invention, such as... Figure 1 As shown, the method includes the following steps:

[0063] Step S102: Based on the anatomical images of the heart, determine multiple target planes within the heart.

[0064] In the scheme provided in step S102, the above-mentioned multiple target planes are cross-sections of the heart, and each of the multiple target planes is perpendicular to the central axis of the aorta.

[0065] In addition, the aforementioned anatomical images of the heart include at least the anatomical images of the aortic valve and its surrounding tissue structures, and each of the aforementioned target planes includes at least the contour information of the heart's own heart valve and the contour information of the tissue structures surrounding the heart valve.

[0066] Step S104: Determine the first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve.

[0067] Step S106: Determine the first push-opening point corresponding to the first initial push point, wherein the location of the first push-opening point is the position reached after the first initial push point moves a first push-opening distance toward the tube wall, and the tube wall is the tube wall of the aortic sinus in the heart.

[0068] Step S108: Based on the first push-opening arrival point, determine the first push-opening range corresponding to each target plane;

[0069] In the scheme provided in step S108, a target shape can be determined within each target plane based on the first push-away arrival point, wherein all the first push-away arrival points are located on the outline of the target shape. Based on the size information of the target shape, the first push-away range corresponding to each target plane can be determined. The size information of the target shape includes its perimeter, area, radius, diameter, and average diameter.

[0070] Specifically, when the type of artificial heart valve is a bulbous expansion valve, the size information of the target graphic can be the area; when the type of artificial heart valve is a self-expanding valve, the size information of the target graphic can be the perimeter.

[0071] Step S110: Determine the second push-open range corresponding to the autologous heart valve based on the first push-open range corresponding to each target plane;

[0072] In the technical solution provided in step S110, the smallest of the multiple first pushing-opening ranges can be determined as the second pushing-opening range.

[0073] Step S112: Based on the second opening range, determine the artificial heart valve that matches the autologous heart valve.

[0074] By using images of the heart's anatomical structure, multiple target planes are determined within the heart. A first initial push point is determined within each target plane, where the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve. A first push-off arrival point is determined corresponding to the first initial push point, where the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance towards the aortic sinus wall. Based on the first push-off arrival point, a first push-off range is determined for each target plane. Based on the first push-off range for each target plane, a second push-off range is determined for the autologous heart valve. Based on the second push-off range, an artificial heart valve matching the autologous heart valve is determined. By determining multiple target planes within an autologous heart valve and identifying the initial push point and push-off arrival point in each target plane, the first push-off range corresponding to each target plane is determined. Furthermore, based on the first push-off range corresponding to each target plane, the second push-off range of the autologous heart valve is determined. This achieves the technical effect of determining an artificial heart valve that matches the autologous heart valve based on the second push-off range, thereby solving the technical problem of inaccuracy caused by relying on experience to determine the heart valve in related technologies.

[0075] In the scheme provided in step S102, a reference plane can first be determined based on the anatomical structure image. Then, multiple cross-sections are selected equidistantly or unequally above the reference plane as target planes, and each of the multiple cross-sections is perpendicular to the aortic axis of the heart. Specifically, when determining the reference plane based on the anatomical structure image, the plane determined by the attachment of the leaflet of the autologous heart valve to the lowest point of the vessel wall can be first determined in the anatomical structure image, and then the above plane can be used as the reference plane.

[0076] Specifically, Figure 2 This is a longitudinal section of the heart. Figure 2 The horizontal and dashed lines in the diagram indicate that h corresponds to the height of the target plane from the reference plane. Point m is the inner side of the leaflet, and point n is the outer side of the leaflet. The distance between points m and n is the leaflet thickness.

[0077] The height can be determined by taking into account the actual situation of the original leaflet and taking values ​​at equal or unequal intervals above the reference plane. For example, a height of 2mm, 4mm, 6mm, or 8mm can be taken on the leaflet.

[0078] In the scheme provided in step S108, when determining the first push-open range corresponding to each target plane based on the first push-open arrival point, a target shape can be determined first based on the first push-open arrival point, wherein all the first push-open arrival points in the target plane are located on the outline of the target shape.

[0079] As an optional implementation, for different types of autologous heart valves, when determining the target shape based on the first push-off arrival point, the structural features of the autologous heart valve in each target plane can be determined first. These structural features include the fusion between any two adjacent leaflets of the autologous heart valve. Based on the structural features of the autologous heart valve, a second push-off arrival point is determined in each target plane. This second push-off arrival point is located at the boundary edge between any two adjacent leaflets. Based on the first push-off arrival point and the second push-off arrival point, the target shape is determined, wherein all second push-off arrival points are located on the outline of the target shape.

[0080] Specifically, the method for determining the second push-opening point varies depending on the fusion status of adjacent leaflets in an autologous heart valve. If no fusion has occurred between adjacent leaflets, the junction point of the two leaflets is determined as the corresponding second push-opening point. If fusion has occurred between adjacent leaflets, the second initial push point at the junction of the two leaflets must first be determined, and then the second push-opening point is determined based on this second initial push point.

[0081] In some embodiments of this disclosure, when two adjacent leaflets fuse at their junction, the method for determining the second push-away arrival point based on the second initial push point is as follows: determining the fusion status between any two adjacent leaflets, wherein the fusion status includes at least one of the following: fusion type, fusion portion length; determining the second push-away distance corresponding to the second initial push point based on the fusion status; determining the second push-away arrival point based on the second push-away distance and the second initial push point, wherein the position of the second push-away arrival point is the position reached after the second initial push point moves the second push-away distance away from the center of the autologous heart valve along the fusion direction.

[0082] In some embodiments of this disclosure, autologous heart valves can be classified into different types based on the number of leaflets and the degree of fusion between adjacent leaflets, and each type of autologous heart valve corresponds to a method for determining the target pattern, including... Figure 6a The first type of autologous heart valve shown is shown in the figure. Figure 7a The second type of autologous heart valve shown is shown in the image. Figure 8a The third type of autologous heart valve shown in the image. Figure 9a The fourth type of autologous heart valve shown, and Figure 10a The fifth type of autologous heart valve is shown in the diagram. It should be noted that this disclosure only selects the above five types of valve structures that are representative of clinical cases to further explain this approach, and does not imply that this disclosure is only applicable to the above five types of situations.

[0083] Specifically, for Figure 6a The first type of autologous heart valve shown is characterized in that the autologous heart valve has three leaflets, and the different leaflets have not fused with each other, or although they have fused, the fusion length is less than a preset first fusion length and can be ignored. The first preset fusion length can be set by the target object itself.

[0084] The positions of the first initial push point, the first push-off arrival point, and the second push-off arrival point are as follows: Figure 6b As shown, there are three initial push points in the autologous heart valve, corresponding to points C1, C2, and C3 in the figure. There are also three first push-out points, corresponding to points X1, X2, and X3 in the figure. Similarly, there are three second push-out points, corresponding to points A1, A2, and A3 in the figure.

[0085] from Figure 6bAs can be seen, when determining the first initial push point, the junction point at the root of any two adjacent leaflets in the autologous heart valve can be determined as the base point. Then, three target line segments are obtained by connecting the base points in pairs. The perpendicular bisectors of the three target line segments are then drawn. The intersection point of each perpendicular bisector with the corresponding inner side of the leaflet is the first initial push point.

[0086] After determining the first initial push point, it is necessary to determine the push-off arrival point corresponding to each first initial push point. Specifically, the first push-off distance of the first initial push point can be determined based on the leaflet thickness and calcification degree corresponding to each initial push point. Then, by moving the first initial push point along the vertical line in a direction away from the center of the heart valve by the first push-off distance corresponding to the first initial push point, the first push-off arrival point can be determined.

[0087] In addition, for the first type of autologous heart valve, the aforementioned baseline point is the second driving point.

[0088] After determining the three first push-opening arrival points and the three second push-opening arrival points, the method can be determined based on the first push-opening arrival points and the second push-opening arrival points. Figure 6c The target shape shown has the first push-out points X1, X2, X3 and the second push-out points A1, A2, A3 all located on the outline of the target shape.

[0089] For example Figure 7a The second type of autologous heart valve shown is characterized in that the number of leaflets in the autologous heart valve is three, and fusion occurs between any two adjacent leaflets, that is, leaflet adhesion and / or calcification occurs between two adjacent leaflets, and the length of adhesion and / or calcification, i.e., the fusion length, is not less than a preset first preset fusion length and is less than a second preset fusion length.

[0090] The positions of the first initial push point, the first push-off arrival point, and the second push-off arrival point are as follows: Figure 7b As shown, there are three initial push points in the autologous heart valve, corresponding to points C1, C2, and C3 in the figure. There are also three first push-out points corresponding to the initial push points, corresponding to points X1, X2, and X3 in the figure. Similarly, there are three second push-out points, corresponding to points A1, A2, and A3 in the figure.

[0091] from Figure 7bAs can be seen, when determining the first initial push point, the endpoint of the fusion point between any two adjacent leaflets of the autologous heart valve, closer to the inner side of the leaflet, can be identified as the second initial push point. The second initial push point is then moved a second distance away from the center of the autologous heart valve along the fusion direction until it reaches the second push point. Connecting each pair of these second push points yields three target line segments. A perpendicular bisector is then drawn from these three target line segments; the intersection of each perpendicular bisector with the corresponding inner side of the leaflet is the first initial push point.

[0092] After determining the initial pushing point, the first pushing distance corresponding to the initial pushing point can be determined based on the leaflet thickness and calcification. The initial pushing point moves the first pushing distance to reach the first pushing arrival point.

[0093] Specifically, the method for determining the first retraction distance is the same as that for Class I autologous heart valves. For the Class II retraction distance, firstly, the fusion type and fusion length of the junction between the corresponding two adjacent leaflets are determined. Then, the degree of retraction at this junction is determined based on the fusion type, and the second retraction distance is determined based on the degree of retraction and the fusion length of the junction. The degree of retraction can be represented by a fusion coefficient, and the second retraction distance is equal to the fusion length multiplied by the fusion coefficient.

[0094] The first push-opening point is determined based on the first push-opening distance, and the second push-opening point is determined based on the second push-opening distance. Specifically, the position where the first initial push point is located after moving the first push-opening distance along the vertical line away from the center of the autologous heart valve is the position of the first push-opening point. Similarly, the position where the second initial push point is located after moving the second push-opening distance along the fusion direction away from the center of the autologous heart valve is the position of the second push-opening point.

[0095] After determining the three first push-opening arrival points and the three second push-opening arrival points, the method can be determined based on the first push-opening arrival points and the second push-opening arrival points. Figure 7c The target shape shown has the first push-out points X1, X2, X3 and the second push-out points A1, A2, A3 all located on the outline of the target shape.

[0096] for Figure 8a The third type of autologous heart valve shown is characterized in that the autologous heart valve has two leaflets, and the two leaflets do not fuse, or although they fuse, the fusion length is less than a preset first fusion length and can be ignored. The first fusion length can be set by the target object itself.

[0097] For type III autologous heart valves, such as Figure 8bAs shown, there are two second push-opening points (i.e., base points). The junction points A1 and A2 at the roots of the two petals are the second push-opening points.

[0098] When determining the first initial push point and the first push-out arrival point, such as Figure 8b As shown, first connect the two base points to obtain the target line segment, and determine the intersection of the perpendicular bisector of the target line segment and the inner side of the two leaflets as the first initial pushing points C1 and C2. Based on the leaflet thickness and calcification degree corresponding to each first initial pushing point, determine the first pushing distance for each first initial pushing point. Move each first initial pushing point along the perpendicular bisector away from the valve center by the corresponding first pushing distance to obtain the first pushing arrival points X1 and X2.

[0099] After determining the two first push-opening arrival points and the two second push-opening arrival points, the following can be determined based on the first push-opening arrival points and the second push-opening arrival points: Figure 8c The target shape shown has the first push-out points X1 and X2 and the second push-out points A1 and A2 all located on the outline of the target shape.

[0100] for Figure 9a The fourth type of autologous heart valve shown is characterized by having three leaflets, but the fusion length between two leaflets is greater than the second preset fusion length. Therefore, the autologous heart valve in this case can be considered as a bicuspid valve, where one leaflet is a normal leaflet and the other leaflet is formed by the fusion of two leaflets.

[0101] like Figure 9b As shown, the fourth type of autologous heart valve has one initial push point, corresponding to point C1 in the figure; one first push-open point, corresponding to X1 in the figure; and three second push-open points, corresponding to A1, A2, and A3 in the figure. Among them, A1 and A2 are the junction points at the roots of two adjacent leaflets that have not fused, i.e., the base points.

[0102] When determining the first initial push point, first connect the two base points to obtain the target line segment, then draw the perpendicular bisector of the target line segment, and determine the intersection of the perpendicular bisector and the inner side of the target leaflet as the first initial push point C1. The target leaflet is a leaflet that has not merged with other leaflets or whose fusion length is less than the first preset fusion length.

[0103] Then, based on the thickness and calcification of the target leaflet, the first push distance is determined, and the first initial push point is moved along the vertical line away from the valve center by the first push distance to reach the first push arrival point.

[0104] When determining the second push-opening arrival point (excluding the two base points) among the three second push-opening arrival points, it is necessary to first determine the second initial push point corresponding to this second push-opening arrival point. This second initial push point is the endpoint near the valve center at the junction of the two leaflets that have fused and whose fusion length is greater than a second preset fusion length. After determining the second initial push point, the second push-opening distance can be determined based on the fusion length and the degree of push-opening at the junction of the fusion points. The second initial push point is then moved along the junction of the fusion points away from the valve center by the second push-opening distance to determine the second push-opening arrival point A3. The degree of push-opening is determined by the fusion type at the junction of the fusion points, which includes fully calcified fusion, partially calcified fusion, and non-calcified fusion.

[0105] After determining one first push-opening arrival point and three second push-opening arrival points, the following can be determined: Figure 9c The target graphic shown has the first push-out point X1 and the second push-out points A1, A2, and A3 all located on the outline of the target graphic.

[0106] for Figure 10a The fifth type of autologous heart valve shown is characterized by having three leaflets, wherein one target leaflet fuses with the other two leaflets, and the fusion length of each leaflet is greater than a first preset fusion length, while the other two leaflets do not fuse or the fusion length is less than the first preset fusion length. In this case, based on the fusion status between the target leaflet and the other two leaflets, the fifth type of autologous heart valve is classified into four types.

[0107] Specifically, the first type of Class V autologous heart valve is characterized by complete fusion between the target leaflet and the other two leaflets, and the fused portion cannot be pushed apart. In this case, the initial push point and the push-apart point in the first type of Class V autologous heart valve are as follows: Figure 10b As shown, it includes two first initial pushing points C1 and C2, two first pushing-away points X1 and X2, and two second pushing-away points A1 and A2. Among them, A1 is the junction point at the base of the leaflets between two unfused leaflets, and A2 is the junction point of the three leaflets.

[0108] When determining the first initial push point, the target line segment can be obtained by connecting the two second push-open arrival points. Then, the perpendicular bisector of the target line segment is drawn. The intersection of the perpendicular bisector with the inner side of the two leaflets other than the target leaflet is determined as the first initial push point. Then, the first push-open distance is determined according to the thickness and fusion of the leaflets where the two first initial push points are located. Finally, the two first initial push points are moved along the perpendicular bisector towards the wall of the aortic sinus by the corresponding first push-open distance to determine the two first push-open arrival points.

[0109] Once the two first push-opening arrival points and the two second push-opening arrival points are determined, then the following can be determined: Figure 10c The target shape shown has the first push-out points X1 and X2 and the second push-out points A1 and A2 all located on the outline of the target shape.

[0110] The second type of Class V autologous heart valve is characterized by a fusion length between the target leaflet and the other two leaflets that is greater than a second preset length, but not completely fused, and the fusion site can be partially pushed apart. In this case, the initial push point and the point of push-apart arrival in the second type of Class V autologous heart valve are as follows: Figure 10d As shown, it includes a first initial push point C1, a first push-open arrival point X1, a second initial push point (i.e., a second push-open arrival point) A3, and two second push-open arrival points A1 and A2.

[0111] The three second push-away points include the junction point A3 at the base of two adjacent leaflets that have not fused, and the other two second push-away points A1 and A2 correspond to the second initial push-away points. The two second initial push-away points are the endpoints near the medial side of the fusion point between the target leaflet and the other two leaflets. The method used to determine the second push-away points corresponding to the two second initial push-away points is the same as that used in type II autologous heart valves, and therefore will not be repeated here.

[0112] When determining the first initial push point, the two second push-off arrival points A1 and A2 mentioned above can be connected to obtain the target line segment. Then, the perpendicular bisector of the target line segment is drawn, and the intersection of the perpendicular bisector and the inner side of the target leaflet is determined as the first initial push point C1. The method for determining the first push-off distance and the first push-off arrival point is the same as that in the second type of autologous heart valve, and will not be repeated here.

[0113] After determining one first push-opening arrival point and three second push-opening arrival points, the following can be determined: Figure 10e The target shape shown has the first push-out point X1 and the second push-out points A1, A2, and A3 all located on the outline of the target shape.

[0114] Compared to the second type of type V autologous heart valve, the third type of type V autologous heart valve exhibits identical fusion between the target leaflet and the other two leaflets. The only difference lies in the methods used to determine the first initial push point and the first push-open arrival point. In this embodiment, there are two first initial push points and two first push-open arrival points.

[0115] Specifically, such as Figure 10fAs shown, there are two first initial push points and two first push-off arrival points, and three second push-off arrival points. Among the three second push-off arrival points, one is the junction point A3 at the root of two adjacent leaflets that have not fused. The other two second push-off arrival points, A1 and A2, correspond to the second initial push points. The two second initial push points are the endpoints near the inner side of the leaflet at the fusion junction between the target leaflet and the other two leaflets. The method used to determine the second push-off arrival points corresponding to the two second initial push points is the same as that used in type II autologous heart valves, and therefore will not be repeated here.

[0116] When determining the first initial push point, first connect A1A3 and A2A3 respectively, to obtain the following: Figure 10f The two target line segments are shown. Then, the perpendicular bisectors of the two target line segments are drawn, and the intersection points C1 and C2 of the two perpendicular bisectors with the inner sides of the other two leaflets (excluding the target leaflet) are determined as the first initial push points. The method for determining the first push distance and the first push arrival points X1 and X2 is the same as that in the second type of autologous heart valve, and will not be repeated here.

[0117] After determining the two first push-opening arrival points and the three second push-opening arrival points, it is possible to determine, as follows: Figure 10g The target shape shown has the first push-out points X1 and X2 and the second push-out points A1, A2 and A3 all located on the outline of the target shape.

[0118] Compared to the second and third types of Class V autologous heart valves, the fourth type of Class V autologous heart valve exhibits identical fusion between the target leaflet and the other two leaflets. The only difference lies in the methods used to determine the first initial push point and the first push-open arrival point. In this embodiment, there are three first initial push points and three first push-open arrival points.

[0119] Specifically, such as Figure 10h As shown, there are three first initial push points and three first push-off arrival points, as well as three second push-off arrival points. Among the three second push-off arrival points, one is the junction point A3 at the root of two adjacent leaflets that have not fused. The other two second push-off arrival points, A1 and A2, correspond to the second initial push points. The two second initial push points are the endpoints near the inner side of the leaflet at the fusion junction between the target leaflet and the other two leaflets. The method used to determine the second push-off arrival points corresponding to the two second initial push points is the same as that used in type II autologous heart valves, and therefore will not be repeated here.

[0120] When determining the first initial push point, the three second push-off arrival points are connected in pairs to obtain three target line segments: A1A2, A1A3, and A2A3. Then, the perpendicular bisector of each target line segment is drawn. The intersection points C1, C2, and C3 of the perpendicular bisector with the inner side of the leaflet are the three first initial push points. The method for determining the three first push-off arrival points X1, X2, and X3 is the same as that used in type II autologous heart valves, and will not be repeated here.

[0121] After determining the three first push-opening arrival points X1, X2, X3 and the three second push-opening arrival points A1, A2, A3, then the following can be determined: Figure 10i The target graphic shown has the first push-out points X1, X2, X3 and the second push-out points A1, A2, A3 all located on the outline of the target graphic.

[0122] After determining the three first push-opening arrival points and the three second push-opening arrival points, it is possible to determine, as follows: Figure 10i The target shape shown has the first push-out points X1, X2, X3 and the second push-out points A1, A2, A3 all located on the outline of the target shape.

[0123] In some embodiments of this disclosure, in the above-mentioned first to fifth types of autologous heart valves, when determining the first push-open distance based on the thickness and calcification degree of the leaflet, the distance between the inner side of the leaflet where the first initial push point is located and the vessel wall can be determined first. Then, a distance coefficient is determined based on the leaflet thickness and calcification degree, and the first push-open distance is obtained by multiplying the distance between the inner side of the leaflet and the vessel wall by the distance coefficient.

[0124] Specifically, when the leaflets are calcified and the calcification extends to the aortic sinus wall, the leaflets can be considered unable to be pushed open, and the aforementioned distance coefficient is 0. When the leaflets are thickened but do not completely fill the aortic sinus, the aforementioned distance coefficient can be between 1 / 3 and 7 / 10, preferably between 1 / 2 and 2 / 3. Leaflet calcification can be divided into free-edge calcification and solid-fill calcification, depending on the type. Specifically, free-edge calcification refers to calcification adhering to the leaflet edge or on the leaflet, but the calcification does not extend to the aortic sinus wall, thus having little impact on the degree of leaflet opening; the distance coefficient can be between 1 / 3 and 7 / 10, preferably between 1 / 2 and 2 / 3. Solid-fill calcification refers to the presence of calcification in the leaflets that extends to the aortic sinus wall; in this case, the calcification completely fills the space between the leaflets and the aortic sinus, therefore the leaflets cannot be pushed open, and the aforementioned distance coefficient is 0.

[0125] For example, for a type I autologous heart valve, the measured distances between the three leaflets and the aortic sinus wall are L1 = 13.7 mm, L2 = 12.6 mm, and L3 = 12.4 mm, respectively, and each leaflet exhibits free edge calcification. Based on the above range of distance coefficient values ​​and the actual aortic valve anatomy, the first retraction distance corresponding to L1 is S1 = 10 mm, with a corresponding distance coefficient of 73%; similarly, the first retraction distance corresponding to L2 is S2 = 8.3 mm, with a corresponding distance coefficient of 65.9%; and the first retraction distance corresponding to L3 is S3 = 7.1 mm, with a corresponding distance coefficient of 57.3%.

[0126] For the type II autologous heart valve, the measured distances between the two leaflets and the aortic sinus wall were L1 = 11.9 mm, L2 = 12.4 mm, and L3 = 14.1 mm, respectively, with free edge calcification present on each leaflet. Based on the above range of distance coefficients and the actual aortic valve anatomy, the first retraction distance corresponding to L1 is S1 = 8 mm, with a distance coefficient of 67.2%; similarly, the first retraction distance corresponding to L2 is S2 = 6.3 mm, with a distance coefficient of 50.8%; and the first retraction distance corresponding to L3 is S3 = 7.7 mm, with a distance coefficient of 54.6%.

[0127] For the type III autologous heart valve, the measured distances between each leaflet and the aortic sinus wall were L1 = 16.8 mm and L2 = 15.4 mm, respectively, and each leaflet exhibited free edge calcification. Based on the above range of distance coefficient values ​​and the actual aortic valve anatomy, the first retraction distance corresponding to L1 is S1 = 5.8 mm, with a corresponding distance coefficient of 34.5%; similarly, the first retraction distance corresponding to L2 is S2 = 8.1 mm, with a corresponding distance coefficient of 52.6%.

[0128] For a type IV autologous heart valve, the non-fused target leaflet was found to have free edge calcification, and the distance L between the medial side of the non-fused target leaflet and the aortic sinus wall was 15.1 mm. Based on the aforementioned range of distance coefficient values ​​and the actual aortic valve anatomy, the first push-away distance corresponding to L is S = 7.1 mm, with a corresponding distance coefficient of 47%. In another embodiment, the distance L between the medial side of the target leaflet and the aortic sinus wall is 13 mm. In this case, the first push-away distance corresponding to L is S = 5.9 mm, with a corresponding distance coefficient of 45.4%.

[0129] For the third type of Class V autologous heart valve, free edge calcification was measured in the other two leaflets besides the target leaflet, with distances of L1 = 14.9 mm and L2 = 8.2 mm from the aortic sinus wall, respectively. The target leaflet is the one fused with the other leaflets. Based on the above range of distance coefficients and the actual aortic valve anatomy, the first displacement distance corresponding to L1 is S1 = 6.3 mm, with a distance coefficient of 42.3%; similarly, the first displacement distance corresponding to L2 is S2 = 3.7 mm, with a distance coefficient of 45.1%.

[0130] When determining the second pushing distance, different fusion types correspond to different degrees of pushing, which can be represented by a fusion coefficient. Specifically, when the fusion type is complete calcification fusion, the pushing degree, i.e., the fusion coefficient, is 0; when the fusion type is partial calcification fusion, the fusion coefficient can take a value between 1 / 3 and 2 / 3, preferably between 2 / 5 and 3 / 5. In this case, the fusion length at the boundary fusion point is the actual boundary fusion length minus the length of the calcified portion. Wherein, when there are multiple calcification sites scattered at the fusion point, the length of the calcified portion is equal to the sum of the lengths of the multiple calcification sites; when the fusion type is non-calcification fusion, the fusion coefficient can take a value between 1 / 3 and 2 / 3, preferably between 2 / 5 and 3 / 5.

[0131] Figure 3 This is a schematic flowchart of a heart valve determination process according to an embodiment of the present disclosure, as shown below. Figure 3 As shown, the process includes the following steps:

[0132] Step S302: Obtain anatomical imaging data of the aortic valve and surrounding tissues;

[0133] Step S304: Determine the location of the virtual valve annulus in the aortic valve;

[0134] In this embodiment of the disclosure, the virtual valve annulus position corresponds to the reference plane, which is the plane determined by the aortic valve leaflet being attached to the lowest point of the vessel wall.

[0135] Step S306: Determine the distance between multiple cross-sections and the virtual valve ring above the virtual valve ring position, and determine multiple cross-sections;

[0136] Step S308: Determine the leaflet condition of the aortic valve corresponding to each of the multiple cross-sections;

[0137] Step S310: Determine the degree of opening of each leaflet in each cross section based on the leaflet condition corresponding to each cross section.

[0138] Step S312: Determine the first pushing range corresponding to each cross section based on the degree of pushing open of each petal leaf;

[0139] Step S314: Compare the first pushing range corresponding to each cross section, and determine the minimum first pushing range as the condition that the implanted stent valve needs to meet.

[0140] Figure 4 This is a schematic flowchart of another heart valve determination process according to an embodiment of the present disclosure, which includes the following steps:

[0141] Step S402: Obtain imaging data of the aorta and surrounding tissue anatomical structures:

[0142] In some embodiments of this disclosure, the above-mentioned image data can be obtained by ultrasound, CT, MRI, etc.

[0143] Step S404: Determine the lesion type based on imaging data;

[0144] In some embodiments of this disclosure, the aforementioned lesion types include aortic stenosis and regurgitation.

[0145] Step S406: Process the image data and extract aortic-related data;

[0146] In some embodiments of this disclosure, processing the image data includes remodeling the structural information of the aorta and surrounding tissues in the image data.

[0147] Step S408: Determine the virtual valve annulus in the aortic valve, and then determine the conditions that the artificial heart valve needs to meet based on the supravalvular anatomical structure data above the virtual valve annulus, the valve annulus anatomical structure data corresponding to the virtual valve annulus, and the subvalvular anatomical structure data below the virtual valve annulus.

[0148] Step S410: Identify artificial heart valves that meet the requirements;

[0149] Step S412: Simulate the situation after artificial heart valve implantation;

[0150] Step S414: Determine the optimal implantable artificial heart valve based on the post-implantation condition.

[0151] Figure 5 This is another method for determining heart valves according to an embodiment of the present disclosure, the method comprising the following steps:

[0152] Step S502: Obtain images of the anatomical structure of the heart;

[0153] Step S504: Based on the anatomical images of the heart, determine multiple target planes within the heart.

[0154] Step S506: Determine the first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve;

[0155] Step S508: Determine the first push-open arrival point corresponding to the first initial push point, wherein the location of the first push-open arrival point is the position reached after the first initial push point moves a first push-open distance toward the tube wall, and the tube wall is the tube wall of the aortic sinus in the heart.

[0156] Step S510: Based on the first push-opening arrival point, determine the first push-opening range corresponding to each target plane;

[0157] Step S512: Determine the second push-open range corresponding to the autologous heart valve based on the first push-open range corresponding to each target plane;

[0158] Step S514: Based on the second push-out range, determine the target setting parameters corresponding to the artificial heart valve, wherein the target setting parameters include the size information of the artificial heart valve;

[0159] Step S516: Determine the artificial heart valve based on the target setting parameters.

[0160] In the technical solution provided in step S514, the target plane is always a plane located above the aortic valve annulus. To ensure that the final determined artificial heart valve is an artificial heart valve that meets actual needs, as an optional implementation, when determining the target setting parameters of the artificial heart valve, the first structural feature of the aortic valve annulus and the second structural feature of the autologous heart valve below the aortic valve annulus can also be determined first, and then the target setting parameters can be determined based on the first structural feature, the second structural feature, and the second push-out range.

[0161] According to embodiments of this disclosure, an embodiment of a device for determining an artificial heart valve based on a multi-plane design is provided. Figure 11 This is a heart valve opening device provided according to embodiments of this disclosure. For example... Figure 11As shown, the device includes: a processing module 110 for determining multiple target planes in the heart based on anatomical images of the heart; an identification module 112 for determining a first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve; a positioning module 114 for determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance towards the aortic sinus in the heart; a calculation module 116 for determining a first push-off range corresponding to each target plane based on the first push-off arrival point; a selection module 118 for determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; and a determination module 120 for determining an artificial heart valve that matches the autologous heart valve based on the second push-off range.

[0162] It should be noted that, Figure 11 The apparatus shown can be used to perform Figure 1 The multi-planar artificial heart valve determination method shown herein, therefore, for Figure 1 The explanations and descriptions of the methods shown also apply to the embodiments of this application, and will not be repeated here.

[0163] According to an embodiment of this disclosure, a non-volatile storage medium is provided. The non-volatile storage medium includes a stored program, wherein, during program execution, the device containing the storage medium executes the following multi-plane-based artificial heart valve determination method: determining multiple target planes in the heart based on an anatomical image of the heart; determining a first initial push point within each target plane, wherein the first initial push point is a point located on the inner contour line of the leaflet of an autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance towards the aortic sinus wall in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; and determining an artificial heart valve matching the autologous heart valve based on the second push-off range.

[0164] As an optional implementation, the above program can also control the device containing the storage medium to execute the following multi-plane-based artificial heart valve determination method: acquiring an anatomical image of the heart; determining multiple target planes in the heart based on the anatomical image; determining a first initial push point in each target plane, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance towards the wall, and the wall is the wall of the aortic sinus in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; determining target setting parameters corresponding to the artificial heart valve based on the second push-off range, wherein the target setting parameters include the size information of the artificial heart valve; and determining the artificial heart valve based on the target setting parameters.

[0165] According to an embodiment of this disclosure, an electronic device is provided, comprising a processor for running a program, wherein, during program execution, the following multi-plane-based artificial heart valve determination method is performed: determining multiple target planes in the heart based on an anatomical image of the heart; determining a first initial push point within each target plane, wherein the first initial push point is a point located on the inner contour line of the leaflet of an autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance toward the aortic sinus wall in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; and determining an artificial heart valve matching the autologous heart valve based on the second push-off range.

[0166] As an optional implementation, the above program can also execute the following multi-plane-based artificial heart valve determination method during runtime: acquiring an anatomical image of the heart; determining multiple target planes in the heart based on the anatomical image; determining a first initial push point in each target plane, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance towards the vessel wall, and the vessel wall is the wall of the aortic sinus in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; determining target setting parameters corresponding to the artificial heart valve based on the second push-off range, wherein the target setting parameters include the size information of the artificial heart valve; and determining the artificial heart valve based on the target setting parameters.

[0167] According to an embodiment of the present invention, an embodiment of a computer terminal is also provided. Figure 12 This is a schematic diagram of the structure of a computer device 1200 according to an embodiment of the present invention.

[0168] In an exemplary embodiment, a computer-readable storage medium including instructions is also provided, such as a memory 1204 including instructions, which can be executed by a processor 1202 of the device 1200 to perform the following multi-plane-based artificial heart valve determination method: determining multiple target planes in the heart based on an anatomical image of the heart; determining a first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance toward the wall, and the wall is the wall of the aortic sinus in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; and determining an artificial heart valve matching the autologous heart valve based on the second push-off range. Optionally, the storage medium may be a non-transitory computer-readable storage medium, such as a ROM, random access memory (RAM), CD-ROM, magnetic tape, floppy disk, and optical data storage device.

[0169] As an optional implementation, the above instructions can be executed by the processor 1202 of the device 1200 to complete the following multi-plane-based artificial heart valve determination method: acquiring an anatomical image of the heart; determining multiple target planes in the heart based on the anatomical image; determining a first initial push point in each of the multiple target planes, wherein the first initial push point is a point located on the inner contour line of the leaflet of the autologous heart valve; determining a first push-off arrival point corresponding to the first initial push point, wherein the location of the first push-off arrival point is the position reached after the first initial push point moves a first push-off distance toward the wall, and the wall is the wall of the aortic sinus in the heart; determining a first push-off range corresponding to each target plane based on the first push-off arrival point; determining a second push-off range corresponding to the autologous heart valve based on the first push-off range corresponding to each target plane; determining target setting parameters corresponding to the artificial heart valve based on the second push-off range, wherein the target setting parameters include the size information of the artificial heart valve; and determining the artificial heart valve based on the target setting parameters.

[0170] In the above embodiments of the present invention, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions of other embodiments.

[0171] In the several embodiments provided in this application, it should be understood that the disclosed technical content can be implemented in other ways. The device embodiments described above are merely illustrative; for example, the division of units can be a logical functional division, and in actual implementation, there may be other division methods. For instance, multiple units or components may be combined or integrated into another system, or some features may be ignored or not executed. Furthermore, the displayed or discussed mutual coupling, direct coupling, or communication connection may be through some interfaces; the indirect coupling or communication connection between units or modules may be electrical or other forms.

[0172] The units described as separate components may or may not be physically separate. The components shown as units may or may not be physical units; that is, they may be located in one place or distributed across multiple units. Some or all of the units can be selected to achieve the purpose of this embodiment according to actual needs.

[0173] Furthermore, the functional units in the various embodiments of the present invention can be integrated into one processing unit, or each unit can exist physically separately, or two or more units can be integrated into one unit. The integrated unit can be implemented in hardware or as a software functional unit.

[0174] If the integrated unit is implemented as a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present invention, in essence, or the part that contributes to the prior art, or all or part of the technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions to cause a computer device (which may be a personal computer, server, or network device, etc.) to execute all or part of the steps of the methods described in the various embodiments of the present invention. The aforementioned storage medium includes various media capable of storing program code, such as USB flash drives, read-only memory (ROM), random access memory (RAM), portable hard drives, magnetic disks, or optical disks.

[0175] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A method for determining a multiplanar based prosthetic heart valve, characterized in that, The method comprises the following steps: determining a plurality of target planes in an anatomical image of a heart according to the anatomical image of the heart; determining a first initial pushing point in each of the plurality of target planes, wherein the first initial pushing point is a point on an inside contour line of a leaflet of a native heart valve; determining a first push-away arrival point corresponding to the first initial pushing point, wherein the first push-away arrival point is a position reached by moving the first initial pushing point a first push-away distance to a pipe wall, the pipe wall being a pipe wall of an aortic sinus in the heart, and the first push-away distance is determined by determining a distance between the inside of the leaflet and the pipe wall, determining a distance coefficient according to a thickness of the leaflet and a degree of calcification, and multiplying the distance between the inside of the leaflet and the pipe wall by the distance coefficient to obtain the first push-away distance; determining a first push-away range corresponding to each of the target planes according to the first push-away arrival point, comprising: determining a target figure according to the first push-away arrival point, wherein the first push-away arrival point is located on a contour line of the target figure; determining size information of the target figure, and determining the first push-away range according to the size information; determining a second push-away range corresponding to the native heart valve according to the first push-away range corresponding to each of the target planes, comprising: determining a first push-away range that is the smallest among a plurality of the first push-away ranges as the second push-away range; determining an artificial heart valve matched with the native heart valve according to the second push-away range.

2. The method of claim 1, wherein the plurality of planes are determined based on a plurality of planes of a plurality of 3D models of the artificial heart valve. The method comprises the following steps: determining a plurality of target planes in an anatomical image of a heart according to the anatomical image of the heart; determining a position of a reference plane in the heart according to the anatomical image; 3. The method of claim 2, wherein the plurality of planes are determined based on a plurality of planes of a plurality of 3D models of the artificial heart valve. selecting a plurality of cross sections above the reference plane, wherein the plurality of cross sections are the plurality of target planes. 4.The method of claim 1, wherein, The reference plane is a plane determined by a lowest point at which a leaflet of the native heart valve is attached to a pipe wall of an aortic sinus. The method comprises the following steps: determining a structure feature of the native heart valve in each of the target planes according to the structure feature of the native heart valve; determining a second push-away arrival point in each of the target planes according to the structure feature of the native heart valve, wherein the second push-away arrival point is located at a junction edge between any two adjacent leaflets of the native heart valve; 5. The method of claim 4, wherein the plurality of planes are determined based on a plurality of planes of a plurality of 3D models of the artificial heart valve. determining a target figure according to the first push-away arrival point and the second push-away arrival point, wherein the second push-away arrival point is located on a contour line of the target figure. The method comprises the following steps: in a case where no fusion occurs between the any two adjacent leaflets, determining a junction point between the any two adjacent leaflets as the second push-away arrival point corresponding to the any two adjacent leaflets; in a case where fusion occurs between the any two adjacent leaflets, determining a second initial pushing point at a junction fusion between the any two adjacent leaflets; and, Determine the second push-away arrival point according to the second initial pushing point.

6. The method of claim 5, wherein the plurality of planes are determined based on a plurality of planes of a plurality of 3D models of the artificial heart valve. Determine the second push-away arrival point according to the second initial pushing point, including: Determine the fusion condition between any two adjacent leaflets, wherein the fusion condition includes at least one of the following: fusion type, fusion part length; Determine the second push-away distance corresponding to the second initial pushing point according to the fusion condition; Determine the second push-away arrival point according to the second push-away distance and the second initial pushing point, wherein the position of the second push-away arrival point is the position reached by moving the second push-away distance from the second initial pushing point along the fusion part in the direction away from the center of the native heart valve.

7. A method for determining a multiplanar based prosthetic heart valve, characterized in that, Including: Obtain the anatomical structure image of the heart; Determine a plurality of target planes in the anatomical structure image of the heart according to the anatomical structure image of the heart; Determine a first initial pushing point in each target plane in the plurality of target planes, wherein the first initial pushing point is a point located on the inner side contour line of the leaflet of the native heart valve; Determine a first push-away arrival point corresponding to the first initial pushing point, wherein the position of the first push-away arrival point is the position reached by moving a first push-away distance from the first initial pushing point to the pipe wall, and the pipe wall is the pipe wall of the aortic sinus in the heart, and determining the first push-away distance includes: determining the distance between the inner side of the leaflet where the first initial pushing point is located and the pipe wall, determining a distance coefficient according to the thickness and the calcification degree of the leaflet, and multiplying the distance between the inner side of the leaflet and the pipe wall by the distance coefficient to obtain the first push-away distance; Determine a first push-away range corresponding to each target plane according to the first push-away arrival point, including: determining a target graph according to the first push-away arrival point, wherein the first push-away arrival point is located on the contour line of the target graph; determining the size information of the target graph, and determining the first push-away range according to the size information; Determine a second push-away range corresponding to the native heart valve according to the first push-away range corresponding to each target plane, including: determining the smallest first push-away range in the plurality of first push-away ranges as the second push-away range; Determine a target setting parameter corresponding to the artificial heart valve according to the second push-away range, wherein the target setting parameter includes the size information of the artificial heart valve; Determine the artificial heart valve according to the target setting parameter.

8. The multi-plane based prosthetic heart valve determination method of claim 7, wherein, The target plane is a plane located above the aortic valve ring, and determining the target setting parameter corresponding to the artificial heart valve according to the second push-away range includes: Determine the first structural feature of the aortic valve ring and the second structural feature of the native heart valve below the aortic valve ring; Determine the target setting parameter according to the first structural feature, the second structural feature and the second push-away range.

9. A determination device for a prosthetic heart valve, characterized in that Including: The processing module is configured to determine a plurality of target planes in the heart according to the anatomical structure image of the heart; The identification module is configured to determine a first initial pushing point in each of the plurality of target planes, wherein the first initial pushing point is a point on an inside profile line of a leaflet of the native heart valve. The positioning module is configured to determine a first push-away arrival point corresponding to the first initial pushing point, wherein the first push-away arrival point is a position reached by the first initial pushing point after moving a first push-away distance, and the position is a wall of an aortic sinus in the heart. The first push-away distance is determined by determining a distance between the inside of the leaflet and the wall, determining a distance coefficient according to a thickness of the leaflet and a degree of calcification, and multiplying the distance between the inside of the leaflet and the wall by the distance coefficient to obtain the first push-away distance. The calculation module is configured to determine a first push-away range corresponding to each of the target planes according to the first push-away arrival point, including: determining a target graph according to the first push-away arrival point, wherein the first push-away arrival point is located on a profile line of the target graph; determining size information of the target graph, and determining the first push-away range according to the size information. The selection module is configured to determine a second push-away range corresponding to the native heart valve according to the first push-away range corresponding to each of the target planes, including: determining a smallest first push-away range in the plurality of first push-away ranges as the second push-away range. The determination module is configured to determine an artificial heart valve matched with the native heart valve according to the second push-away range.

10. A non-volatile storage medium, comprising: The non-volatile storage medium includes a stored program, wherein the program controls a device in which the non-volatile storage medium is located to perform the multi-plane based artificial heart valve determination method in any one of claims 1 to 6 when the program is running.

11. An electronic device comprising a processor, characterized in that The processor is configured to run a program, wherein the program performs the multi-plane based artificial heart valve determination method in any one of claims 1 to 6 when the program is running.

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