A vaccine shaking device

Abstract

This invention discloses a vaccine mixing device, comprising: a body (100), the middle of which is a working area for mixing vaccines; a mixing mechanism (200), including a central connecting component (202), two sets of base plates (201), and two sets of rocker arms (207), wherein the central connecting component (202) is rotatably disposed at the center of the working area of ​​the body (100), the two sets of base plates (201) are arranged opposite to each other on both sides of the central connecting component (202) along a first direction, and the two sets of rocker arms (207) are arranged opposite to each other on both sides of the central connecting component (202) along a second direction, one end of each rocker arm (207) is connected to the central connecting component (202), and the other end is provided with a clamping mechanism for clamping vaccine vials; and a driving mechanism (300), including a driver (301) to drive the central connecting component (202) to rotate. This invention can achieve the effect of automatic mixing of vaccine vials. In addition, by designing a dual-arm multi-mode feature, it can meet different requirements for mixing vaccines at one time.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a vaccine shaking device. Background Technology

[0002] Vaccines are preventive biological products used for human immunization to prevent and control the occurrence and spread of diseases. Vaccines containing adsorbents should be thoroughly shaken before use. For novel coronavirus mRNA vaccines, the vial should be gently inverted (upside down) 10 times to mix thoroughly, and should not be shaken vigorously. Manual shaking by vaccination personnel is inefficient, prone to fatigue, and occasionally results in vaccination without proper shaking. Furthermore, long-term shaking can cause occupational health damage to the arms of vaccination personnel. Moreover, with the market launch and use of vaccines using novel mRNA technology, the shaking process differs significantly from that of previous adsorbent-containing vaccines; it is more complex, time-consuming, and difficult to control in terms of whether the shaking is performed correctly. Because shaking can affect vaccine efficacy, the requirements for shaking operation are becoming increasingly stringent. Therefore, it is necessary to research a vaccine shaking device to improve the automation and accuracy of shaking. Summary of the Invention

[0003] In view of the problems mentioned above and / or existing medical devices, this invention is proposed. The technical problem to be solved by this invention is that the manual shaking method used by vaccination personnel is inefficient, easily leads to fatigue, and occasionally results in vaccination without proper shaking. Furthermore, long-term shaking can cause occupational health damage to the arms of vaccination personnel. Moreover, with the market launch and use of vaccines using novel mRNA technology, the shaking process differs significantly from that of previous adsorbent-containing vaccines, making the shaking operation more complex, time-consuming, and difficult to control in terms of whether the operator is shaking correctly.

[0004] To achieve the above objectives, the present invention provides a vaccine mixing device, comprising,

[0005] The body, with the central part of the body serving as the working area for mixing the vaccine;

[0006] The shaking mechanism includes a central connecting assembly, two sets of base plates, and two sets of rocker arms. The central connecting assembly is rotatably disposed at the center of the working area of ​​the machine body. The two sets of base plates are arranged opposite to each other on both sides of the central connecting assembly along a first direction. The two sets of rocker arms are arranged opposite to each other on both sides of the central connecting assembly along a second direction, and the two sets of base plates are fixed to the working area of ​​the machine body. One end of each set of rocker arms is connected to the central connecting assembly, and the other end is provided with a clamping mechanism for holding the vaccine vial.

[0007] A drive mechanism, including a driver, is located below the body and is drively connected to the central connecting component to drive the central connecting component to rotate.

[0008] In some embodiments, the two sets of rocker arms include at least one fully shaking robotic arm, the distal end of which is fixedly connected to a clamping mechanism, which revolves synchronously with the fully shaking robotic arm under the rotation of the central connecting assembly.

[0009] In some embodiments, the two sets of rocker arms include at least one lightly reversing robotic arm. A first bearing is provided at the distal end of the lightly reversing robotic arm. A gear is rotatably disposed outside the first bearing. The machine body has an annular rack arranged in its working area. The gear meshes with the annular rack. A clamping mechanism is fixedly connected to the outside of the gear. The clamping mechanism and the lightly reversing robotic arm revolve synchronously under the rotation of the central connecting assembly. At the same time, the gear rotates on the annular rack, and the clamping mechanism rotates under the drive of the gear.

[0010] In some embodiments, the central connection assembly includes a connection housing, the bottom of which is connected to the driver via a connection shaft, and the side wall of the connection housing has at least two mounting slots.

[0011] Each of the two sets of rocker arms has a plug at one end connected to the central connecting component. The shape of the plug matches the mounting slot. The two sets of rocker arms are connected and fixed to the central connecting component by inserting the plug into the corresponding mounting slot.

[0012] In some embodiments, the upper part of the connecting shell has a movable groove, the movable groove has a plurality of sliding grooves around its periphery, a movable component is disposed in the movable groove, the movable component has a plurality of through holes corresponding to the sliding grooves around its periphery, and an elastic insertion component is disposed on the movable component, the elastic insertion component including a plurality of insert rods inserted into the through holes;

[0013] The insert has a mounting hole, and when the insert is inserted into the corresponding mounting slot, the mounting hole corresponds to the sliding groove and the insert rod in the connecting shell.

[0014] In some embodiments, the movable component includes a movable plate with a plurality of through holes around its perimeter, a connecting block fixedly connected to the center of the movable plate, the connecting block extending to the outside of the connecting shell and having a pull ring at its top.

[0015] In some embodiments, the resilient insert assembly further includes a plurality of baffles and springs, the baffles and springs being mounted above the movable plate, the top end of the insert rod being fixedly connected to the lower part of the baffles, and the springs being fixed above the baffles.

[0016] In some embodiments, the insert block has a hollow structure, and the two sets of rocker arms are provided with flow grooves. The insert block is connected to the clamping mechanism through the flow grooves.

[0017] Several sliding grooves have air holes connected to their lower surfaces, and a sealing assembly is snapped into the lower surface of the connecting shell; the air holes are connected to the sealing assembly.

[0018] A fan is located below the driver, and the fan is connected to an air vent through a sealing assembly.

[0019] In some embodiments, the sealing assembly includes a second bearing, a connecting ring is sleeved inside the second bearing, the connecting ring has a plurality of connecting holes, the connecting ring is snapped into an air hole, the second bearing is snapped into the body, and the connecting holes are connected to the air hole.

[0020] In some embodiments, a first duct is provided at the bottom of the machine body, and four suction cups are provided at the four corners of the bottom of the machine body. The air inlet of the fan is connected to the first duct, and the first duct is connected to the four suction cups respectively.

[0021] In some embodiments, the clamping mechanism includes an arc-shaped first clamping plate and a second clamping plate. The two sides of the first clamping plate and the second clamping plate are connected by a telescopic tube. A return spring is provided outside the telescopic tube. An adsorption groove is provided in both the first clamping plate and the second clamping plate. The adsorption groove is connected to the flow groove in the two sets of rocker arms.

[0022] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0023] This vaccine mixing device, when the actuator is running, drives the connecting shell to rotate via the connecting shaft. Since the connecting shell is connected to a rocker arm, the actuator causes the rocker arm to swing along the connecting shell, achieving the effect of mixing the vaccine inside the vial. Furthermore, this invention features a dual-arm, multi-mode design. Addressing different requirements for vaccine mixing, the two sets of robotic arms are specifically configured. The fully mixing robotic arm uses a uniform or variable speed mixing method (pre-set drive mode) for mixing vaccines containing adsorbents (fully mixing). The gently inverting robotic arm can uniformly invert and mix, used for mixing vaccines using novel mRNA technology (the vaccine vial needs to be gently inverted 10 times before use, and should not be shaken violently). The robotic arms provided by this invention have a high degree of human-like operation, eliminating the need for manual control, making it easier to determine the mixing effect of the vaccine inside the vial, and achieving automated control. Attached Figure Description

[0024] To more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are merely exemplary, and those skilled in the art can derive other embodiments based on the provided drawings without creative effort.

[0025] The structures, proportions, sizes, etc. illustrated in this specification are only for the purpose of assisting those skilled in the art in understanding and reading the content disclosed herein, and are not intended to limit the conditions under which the present invention can be implemented. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportions, or adjustments to the size, without affecting the effects and objectives that the present invention can produce, should still fall within the scope of the technical content disclosed in the present invention.

[0026] Figure 1 This is a schematic diagram of the overall structure of a vaccine shaking device according to an embodiment of the present invention (with the protective cover open).

[0027] Figure 2 This is a schematic diagram of the overall structure of a vaccine shaking device according to an embodiment of the present invention (with the protective cover closed).

[0028] Figure 3 This is a schematic diagram of the overall structure of the shaking mechanism in a vaccine shaking device according to an embodiment of the present invention.

[0029] Figure 4 This is an exploded structural diagram of the shaking mechanism in a vaccine shaking device according to an embodiment of the present invention.

[0030] Figure 5 for Figure 1 Enlarged structural diagram at point A in the middle.

[0031] Figure 6 This is a schematic diagram of the cross-sectional structure of the rocker arm in a vaccine shaking device according to an embodiment of the present invention.

[0032] Figure 7 This is a schematic diagram of the drive mechanism in a vaccine shaking device according to an embodiment of the present invention.

[0033] Figure 8 for Figure 7 Enlarged structural diagram at point B.

[0034] 100 Body, 101 Ring rack, 102 Protective cover, 103 Control buttons, 104 Heat dissipation vent;

[0035] 200 Shaking mechanism, 201 Base plate, 202 Center connecting assembly, 202a Connecting shell, 202b Movable groove, 202c Slide groove, 202d Air hole, 202e Mounting slot, 203 Elastic insertion assembly, 203a Insert rod, 203b Baffle, 203c Spring, 204 Movable assembly, 204a Movable plate, 204b Through hole, 204c Connecting block, 204d Pull ring, 205 Sealing assembly, 205a Second bearing, 205b Connecting ring, 205c Connecting hole, 206 Connecting shaft, 207 Rocker arm, 207a Insert block, 207b Mounting hole, 207c Fully shaking robotic arm, 207d Flow groove, 207e Gear, 207f First bearing, 207g First clamping plate, 207h Telescopic tube, 207i Lightly reversing robotic arm, 207j Second clamping plate, 207k Adsorption groove;

[0036] 300 Drive mechanism, 301 Driver, 302 Fan, 303 First duct, 304 Second duct, 305 Suction cup.

[0037] In the various figures, the same or corresponding reference numerals indicate the same or corresponding parts. Detailed Implementation

[0038] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be further described in detail below with reference to the accompanying drawings. Here, the illustrative embodiments and descriptions of the present invention are used to explain the present invention, but are not intended to limit the present invention.

[0039] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0040] It should be understood that the terms "comprising / including," "consisting of," or any other variations are intended to cover non-exclusive inclusion, such that a product, apparatus, process, or method that comprises a list of elements includes not only those elements but may also include, where necessary, other elements not expressly listed, or elements inherent to such a product, apparatus, process, or method. Without further limitation, an element defined by the phrases "comprising / including," "consisting of," does not exclude the presence of additional identical elements in the product, apparatus, process, or method that includes said element.

[0041] It should also be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device, component or structure referred to must have a specific orientation, be constructed or operated in a specific orientation, and should not be construed as a limitation of the present invention.

[0042] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0043] This invention aims to provide a vaccine shaking device that simulates the characteristics of human shaking. It adopts a dual-arm, multi-mode shaking configuration, distinguishing the shaking function of conventional vaccines containing adsorbents from that of novel mRNA vaccines. This solves the problems of lack of quality control, low efficiency, and fatigue and occupational health hazards of shaking operations by ordinary manual shaking methods. It is especially suitable for shaking operations before vaccination.

[0044] To better understand the above technical solution, the following will provide a detailed explanation of the technical solution in conjunction with the accompanying drawings and specific implementation methods.

[0045] like Figure 1-8 As shown, the present invention provides a vaccine mixing device, mainly comprising a body 100, a mixing mechanism 200, and a driving mechanism 300. The body 100 has a central working area for mixing the vaccine before administration, and a control button 103 is located at the front of the body 100. The mixing mechanism 200 includes a central connecting component 202, two sets of base plates 201, and two sets of rocker arms 207. The central connecting component 202 is rotatably disposed at the center of the working area of ​​the body 100. The two sets of base plates 201 are arranged opposite each other on both sides of the central connecting component 202 along a first direction, and the two sets of rocker arms 207 are arranged opposite each other on both sides of the central connecting component 202 along a second direction. The two sets of base plates 201 are fixed to the working area of ​​the body 100. One end of each rocker arm 207 is connected to the central connecting component 202, and the other end is provided with a clamping mechanism for holding the vaccine vial. The driving mechanism 300 includes a driver 301, disposed below the body 100 and connected to the central connecting component 202 for driving the central connecting component 202 to rotate.

[0046] The first direction can be one of the directions toward the body 100, such as the direction parallel to the control button 103. The second direction can be another direction toward the body 100, such as the direction perpendicular to the control button 103. The first direction and the second direction are perpendicular to each other. The two sets of base plates 201 and the two sets of rocker arms 207 are arranged in a cross shape, with the central connecting component 202 as the central base point.

[0047] See details Figure 1 , Figure 2 The main body 100 is the main structure of the entire shaking device. It serves as the base for installing related components and providing support. For example, it can adopt a box-shaped structure. To facilitate handling and carrying, its thickness is designed to be as thin as possible while meeting design requirements. For example, it is similar to a flat plate structure, and together with the outer cover, the whole resembles a suitcase.

[0048] The middle part of the body 100 is the working area for shaking before vaccination. A control button 103 is provided at the front of the body 100. The body 100 can be powered by its own battery or temporarily connected to an AC power source. The control button 103 is electrically connected to the drive mechanism 300 and is used to drive and control the drive mechanism 300.

[0049] Considering the safety of the bearings and large gears during operation, a protective cover 102 can be further provided on the top of the body 100. The protective cover 102 is hinged to the side of the body 100 opposite to the control button 103. The protective cover 102 can provide protection for the entire device in working or non-working states, preventing the external environment from affecting the vaccine shaking operation, or from causing contamination to the internal structure (such as gears) when idle.

[0050] See also Figure 3 , Figure 4 The shaking mechanism 200 includes a central connecting component 202, two sets of base plates 201 and two sets of rocker arms 207. The central connecting component 202 is rotatably disposed at the center of the working area of ​​the machine body 100. The two sets of base plates 201 are arranged opposite to each other on both sides of the central connecting component 202 along a first direction. The two sets of rocker arms 207 are arranged opposite to each other on both sides of the central connecting component 202 along a second direction. The two sets of base plates 201 are fixed to the working area of ​​the machine body 100. One end of the two sets of rocker arms 207 is connected to the central connecting component 202, and the other end is provided with a clamping mechanism for clamping vaccine vials.

[0051] In some embodiments, the central connecting assembly 202 is rotatably disposed at the center of the working area of ​​the body 100, including a connecting shell 202a. The bottom of the connecting shell 202a is connected to the bottom driver 301 via a connecting shaft 206. At least two mounting slots 202e are provided on the side wall of the connecting shell 202a. Each end of the two sets of rocker arms 207 connected to the central connecting assembly 202 includes a plug 207a. The shape of the plug 207a matches the mounting slot 202e. The two sets of rocker arms 207 are inserted into the corresponding mounting slots 202e via the plug 207a and are connected and fixed to the central connecting assembly 202. The central connecting assembly 202 rotates under the drive of the drive mechanism 300, which in turn drives the two sets of rocker arms 207 to rotate. When the two sets of rocker arms 207 rotate, they shake the vaccine vials held by the clamping mechanism to mix them.

[0052] The central connecting component 202 can specifically adopt a cylindrical structure. Two sets of base plates 201 are set in the working area of ​​the machine body 100 and kept fixed. The ends of the two sets of base plates 201 near the central connecting component 202 are separated from the connecting shell 202a by a small gap, or are in contact but not connected, to ensure the smooth rotation of the central connecting component 202. The two sets of base plates 201 are fixed as a stop and limit structure when the two sets of rocker arms 207 rotate.

[0053] See Figure 1 , Figure 7 , Figure 8 The drive mechanism 300 includes a driver 301, which is disposed below the body 100 and is driveably connected to the central connecting assembly 202 to drive the central connecting assembly 202 to rotate. Specifically, the output shaft of the driver 301 is driveably connected to the connecting shaft 206, driving the connecting shaft 206 to rotate.

[0054] See also Figure 3 , Figure 4 The connecting shell 202a has a movable groove 202b on its upper interior. The movable groove 202b has several sliding grooves 202c around its circumference, which are evenly spaced on the circumference. A movable component 204 is provided inside the movable groove 202b. The movable component 204 has several through holes 204b around its circumference that correspond to the sliding grooves 202c. An elastic insertion component 203 is provided on the movable component 204. The elastic insertion component 203 includes several insertion rods 203a that are inserted into the through holes 204b. An installation hole 207b is provided on the insertion block 207a. When the insertion block 207a is inserted into the corresponding installation slot 202e, the installation hole 207b corresponds to the sliding groove 202c and the insertion rod 203a in the connecting shell 202a.

[0055] The bottom end of the insertion rod 203a can be designed as a bevel, with the bevel facing outwards. When it is necessary to insert and connect the rocker arm 207, simply insert the insertion block 207a into the mounting slot 202e. At this time, the insertion rod 203a will move upwards due to the pressure of the insertion block 207a on its bevel. After the insertion block 207a has moved a certain distance within the mounting slot 202e, the insertion rod 203a will align with the mounting hole 207b. At this point, the insertion rod 203a can elastically move downwards, sequentially inserting into the sliding groove 202c and the mounting hole 207b, thus achieving the insertion and connection fixation of the rocker arm 207. This allows the shaking device to be quickly inserted and fixed, and can be adjusted accordingly for different shaking requirements.

[0056] More specifically, the movable component 204 includes a movable plate 204a with several through holes 204b around its perimeter. A connecting block 204c is fixedly connected to the center of the movable plate 204a. The connecting block 204c extends to the outside of the connecting shell 202a and has a pull ring 204d at its top. This allows the movable plate 204a to be moved upwards by pulling the pull ring 204d.

[0057] More specifically, the elastic insertion assembly 203 also includes several baffles 203b and springs 203c. The baffles 203b and springs 203c are installed above the movable plate 204a. The top of the insertion rod 203a is fixedly connected to the bottom of the baffle 203b. The springs 203c are fixed above the baffles 203b. That is, the springs 203c are located between the baffles 203b and the top inner wall of the connecting shell 202a. The top movement distance should ensure that the insertion rod 203a can be smoothly dislodged from the mounting hole 207b when it moves upward.

[0058] When it is necessary to disassemble or replace different rocker arms 207, simply pull the pull ring 204d upwards to move the movable plate 204a upwards. At this time, the movable plate 204a will drive the baffle 203b to move, so that the insertion rod 203a will disengage from the mounting hole 207b under the action of the baffle 203b. Then the insertion block 207a can be removed. The staff can easily install and disassemble the rocker arm 207, thereby reducing the difficulty of disassembly and replacement when using the shaking device and expanding the application range.

[0059] In some embodiments, see continue to see Figure 4 , Figure 6The insert 207a has a hollow structure, and the two sets of rocker arms 207 have flow grooves 207d. The insert 207a is connected to the clamping mechanism through the flow grooves 207d. Several sliding grooves 202c are connected to air holes 202d below. A sealing component 205 is snapped into the lower part of the connecting shell 202a. The air holes 202d are connected to the sealing component 205. Furthermore, a fan 302 is provided below the driver 301. The fan 302 is connected to the air holes 202d through the sealing component 205. During use, the vaccine vial is held in the clamping mechanism. After startup, the blower 302 will also run, at which time the blower 302 will draw air from the air hole 202d. The upper movable groove 202b is sealed and blocked by the movable plate 204a. The air hole 202d will draw gas along the flow groove 207d in the rocker arm 207. Since the flow groove 207d is also connected to the clamping mechanism at the far end, it will draw gas from the clamping mechanism, so that negative pressure is generated in the clamping mechanism. This can increase the clamping effect on the vaccine vial, prevent damage to the vaccine vial due to excessive mechanical clamping, ensure the stability and safety of fixing the vaccine vial, and also avoid the situation where the vaccine vial slips due to centrifugal force.

[0060] Specifically, the sealing assembly 205 includes a second bearing 205a, inside which is a connecting ring 205b. The diameter of the connecting ring 205b is smaller than that of the second bearing 205a, and it contracts inward relative to the second bearing 205a. Several connecting holes 205c are provided on the connecting ring 205b, which can be precisely engaged within the air hole 202d (the air hole 202d is actually an annular structure, shown in cross-section in the figure). The second bearing 205a is engaged within the body 100, and the connecting holes 205c communicate with the air hole 202d. After the fan 302 starts, air is drawn from the air hole 202d through the connecting holes 205c on the connecting ring 205b. The sealing assembly 205 ensures the installation and smooth rotation of the entire central connecting assembly 202 at the bottom of the body 100, and ensures airtightness during rotation.

[0061] In some embodiments, see continue to see Figure 5 , Figure 6The clamping mechanism includes an arc-shaped first clamping plate 207g and a second clamping plate 207j. The two sides of the first clamping plate 207g and the second clamping plate 207j are connected by a telescopic tube 207h. A return spring (not shown in the figure) is provided outside the telescopic tube 207h. The first clamping plate 207g and the second clamping plate 207j are hollow structures, each with an adsorption groove 207k. The adsorption groove 207k is connected to the flow groove 207d in one of the rocker arms 207. Specifically, the adsorption groove 207k of the first clamping plate 207g is connected to the flow groove 207d in one of the rocker arms 207, and the adsorption groove 207k of the second clamping plate 207j is connected to the adsorption groove 207k of the first clamping plate 207g through the telescopic tube 207h. Both the first clamping plate 207g and the second clamping plate 207j have a semi-circular or near-semi-circular structure. The inner wall has multiple small adsorption holes that connect to the adsorption grooves 207k. An elastic pad can be added to the inner wall. When the first clamping plate 207g and the second clamping plate 207j hold the vaccine bottle, the adsorption grooves 207k inside the first clamping plate 207g and the second clamping plate 207j are in contact with the vaccine bottle at this time. A negative pressure is formed at the contact surface, which enhances the retention effect of the vaccine bottle.

[0062] See also Figure 7 , Figure 8 The bottom of the body 100 is provided with a first conduit 303, and four suction cups 305 are provided at the four corners of the bottom of the body 100. The air inlet of the fan 302 is connected to the connecting ring 205b and the first conduit 303. The first conduit 303 is connected to the four suction cups 305 respectively. The bottom of the body 100 is also provided with a second conduit 304, and the air outlet of the fan 302 is connected to the second conduit 304. The second conduit 304 extends into the body 100. When the blower 302 is running, it draws gas from the flow channel 207d, the first clamping plate 207g, and the second clamping plate 207j. Simultaneously, it draws gas from the first conduit 303, creating a negative pressure environment inside the four suction cups 305 connected to the first conduit 303. This ensures that the shaking device can adhere to the table or ground during the shaking of the vaccine vial, guaranteeing stability during the shaking process. Furthermore, the gas drawn by the blower 302 is discharged into the machine body 100 through the second conduit 304, accelerating air circulation within the machine body 100 and ventilating and cooling it. This ensures that the ambient temperature inside the machine body 100 during shaking does not become too high, which is essential for ensuring the vaccine's efficacy.

[0063] Based on this, several heat dissipation vents 104 are provided on the back of the machine body 100 to ventilate and dissipate heat inside the protective cover 102 when the machine is closed for shaking in certain situations, so as to avoid overheating of gears due to friction during long-term shaking operations.

[0064] In this invention, each of the two sets of rocker arms 207 includes at least one fully agitating rocker arm 207. A clamping mechanism is fixedly connected to the distal end of the fully agitating rocker arm 207. This clamping mechanism and the fully agitating rocker arm 207 revolve synchronously under the rotation of the central connecting assembly 202. By pre-setting the drive mode of the driver 301 (e.g., using programmable control or a conventional controller), the fully agitating rocker arm 207 is agitated at a uniform or variable speed for the agitation of vaccines containing adsorbents.

[0065] On the other hand, the two sets of rocker arms 207 also include a lightly reversing robotic arm 207i. A first bearing 207f is located at the distal end of the lightly reversing robotic arm 207i, and a gear 207e is rotatably mounted outside the first bearing 207f. A ring rack 101 is arranged in the working area of ​​the machine body 100. The gear 207e meshes with the ring rack 101. A clamping mechanism is fixedly connected to the outside of the gear 207e. This clamping mechanism and the lightly reversing robotic arm 207i revolve synchronously under the rotation of the central connecting assembly 202. Simultaneously, the gear 207e rotates on the ring rack 101, and the clamping mechanism rotates under the drive of the gear 207e. By using the lightly reversing robotic arm 207i alone or simultaneously, variable speed or uniform speed + inverted shaking can be achieved for mixing operations of vaccines using novel mRNA technology routes (the vaccine vial needs to be gently inverted 10 times before use, and should not be shaken violently). By reasonably setting the number of teeth on the gear rack, the gear 207e can reverse the required number of times (e.g., 10 times) when it moves back and forth on the ring rack 101 one or more times, so as to automatically achieve the mixing effect of the novel mRNA technology route vaccine.

[0066] It should be noted that the above two shaking methods can be used individually or in combination. When used individually, both sets of rocker arms 207 are designed to either fully shake or gently invert the robotic arm 207i. When used in combination, both sets of rocker arms 207 are designed to be both fully shaken and gently inverted. Simply replace the corresponding rocker arm 207 by inserting / removing the plug 207a, and simultaneously add or remove the corresponding annular rack 101. This invention preferably uses the two sets of robotic arms in combination, with targeted arm configurations for each set, employing a dual-arm, multi-mode shaking method to meet the current requirement of shaking two different vaccines simultaneously.

[0067] It should also be noted that the number of rocker arms 207 can be flexibly adjusted as needed. For example, multiple rocker arms 207 for fully shaking and / or multiple lightly reversing robotic arms 207i can be provided on both sides of the substrate 201. In this case, the size of the body 100 and the central connecting component 202 can be appropriately increased as needed. This is foreseeable and within the scope of the concept of the present invention.

[0068] It should also be noted that the present invention can also use a chip program control plus a small motor drive, that is, the motor is directly controlled by the chip program to replace the large gear for shaking control. The chip program pre-sets the number of rotations, direction and speed of the motor so as to realize that the rocker arm 207 can rotate forward and backward in a predetermined manner.

[0069] The working principle of this invention is as follows: When using the shaking device, the vaccine bottle to be clamped is placed between the first clamping plate 207g and the second clamping plate 207j. By pulling the second clamping plate 207j outward, and then placing the vaccine bottle, the pulling of the second clamping plate 207j is released. At this time, the return spring outside the telescopic tube 207h drives the second clamping plate 207j to fit with the first clamping plate 207g, thereby completing the initial clamping and fixing of the vaccine bottle.

[0070] After the vaccine vial is initially secured, the driver 301 can be started via control button 103. At the same time as the driver 301 starts, the fan 302 will also run. At this time, the fan 302 will draw air from the air hole 202d through the connecting ring 205b. Since the upper movable groove 202b is sealed and blocked by the movable plate 204a, the air hole 202d will draw gas from the adsorption groove 207k inside the first clamping plate 207g and the second clamping plate 207j along the flow groove 207d inside the rocker arm 207. Since the adsorption groove 207k inside the first clamping plate 207g and the second clamping plate 207j are in contact with the vaccine vial at this time, and the surfaces of the first clamping plate 207g and the second clamping plate 207j are provided with elastic pads, a negative pressure is formed at the contact point to enhance the clamping effect.

[0071] When the driver 301 is running, the driver 301 will drive the connecting shell 202a to rotate through the connecting shaft 206. Since the connecting shell 202a is fixed with a rocker arm 207, the driver 301 will drive the rocker arm 207 to swing, thereby achieving the effect of shaking the vaccine inside the vaccine vial. At the same time, during the swinging process of the rocker arm 207, the gear 207e of the lightly reversed mechanical arm 207i will rotate along the annular rack 101 during the swinging process. This allows the shaking device to shake the vaccine inside the vaccine vial through the rocker arm 207, while simultaneously rotating the first clamping plate 207g and the second clamping plate 207j along the first bearing 207f, thereby achieving the reverse shaking of the vaccine vial.

[0072] When the fan 302 is running, on the one hand, the fan 302 will draw gas from the first clamping plate 207g and the second clamping plate 207j, and on the other hand, the fan 302 will draw gas from the first duct 303, so that the four suction cups 305 connected to the first duct 303 are in a negative pressure state. Furthermore, the gas drawn by the fan 302 will be discharged into the body 100, thereby accelerating the air circulation inside the body 100.

[0073] When a new rocker arm 207 needs to be connected, simply insert the plug 207a into the mounting slot 202e. The plug rod 203a will then move upward due to the pressure of the plug 207a on its inclined surface. After the plug 207a has moved a certain distance in the mounting slot 202e, the plug rod 203a will align with the mounting hole 207b. At this point, the plug rod 203a will quickly move downward under the force of the spring 203c, allowing the rocker arm 207 to be installed quickly. When the rocker arm 207 needs to be disassembled, simply pull the pull ring 204d upward to move the movable plate 204a upward. The movable plate 204a will then move the baffle 203b, causing the plug rod 203a to disengage from the mounting hole 207b under the action of the baffle 203b. The plug 207a can then be removed.

[0074] When it is necessary to change the shaking method, simply install the rocker arm 207 into the mounting slot 202e on one side of the connecting shell 202a. Since the other side of the body 100 does not have a ring rack 101, the rocker arm 207 will only swing along the connecting shell, so that the shaking device can achieve revolution shaking. That is, while one side swings the arm to shake, the other side can also rotate around one end of the rocker arm 207 as the center. This makes the shaking device not only suitable for shaking vaccines containing adsorbents, but also for inverting and mixing vaccine vials.

[0075] It should be noted that the term "one embodiment" or "embodiment" as used above refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The phrase "in one embodiment" appearing in different places in this specification does not necessarily refer to the same embodiment, nor is it a single or selective embodiment that excludes other embodiments.

[0076] While several specific implementation details are included in the foregoing discussion, these should not be construed as limiting the scope of the invention. Certain features described in the context of individual embodiments may also be implemented in combination in a single implementation. Conversely, various features described in the context of a single implementation may also be implemented individually or in any suitable sub-combination in multiple implementations.

[0077] The various embodiments of the present invention have been described above. These descriptions are exemplary and not exhaustive, nor are they limited to the disclosed embodiments. Many modifications and variations will be apparent to those skilled in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen to best explain the principles, practical application, or technical improvements to the embodiments in the market, or to enable others skilled in the art to understand the embodiments disclosed herein.

Claims

1. A vaccine mixing device, characterized in that, include: The body (100) has a working area in the middle for mixing the vaccine. The shaking mechanism (200) includes a central connecting assembly (202), two sets of base plates (201), and two sets of rocker arms (207). The central connecting assembly (202) is rotatably disposed at the center of the working area of ​​the body (100). The two sets of base plates (201) are arranged opposite to each other on both sides of the central connecting assembly (202) along a first direction. The two sets of rocker arms (207) are arranged opposite to each other on both sides of the central connecting assembly (202) along a second direction. The two sets of base plates (201) are fixed to the working area of ​​the body (100). One end of each set of rocker arms (207) is connected to the central connecting assembly (202), and the other end is provided with a clamping mechanism for clamping vaccine vials. The drive mechanism (300) includes a driver (301), which is disposed below the body (100) and is drively connected to the central connection assembly (202) to drive the central connection assembly (202) to rotate; The two sets of rocker arms (207) include at least one fully shaking mechanical arm (207c), the distal end of which is fixedly connected to a clamping mechanism, which revolves synchronously with the fully shaking mechanical arm (207c) under the rotation of the central connecting assembly (202); The two sets of rocker arms (207) include at least one light reversing mechanical arm (207i). The light reversing mechanical arm (207i) is provided with a first bearing (207f) at its distal end. A gear (207e) is rotatably provided outside the first bearing (207f). The machine body (100) has an annular rack (101) arranged in its working area. The gear (207e) meshes with the annular rack (101). A clamping mechanism is fixedly connected to the outside of the gear (207e). The clamping mechanism and the light reversing mechanical arm (207i) revolve synchronously under the rotation of the central connecting assembly (202). At the same time, the gear (207e) rotates on the annular rack (101). The clamping mechanism rotates under the drive of the gear (207e).

2. The vaccine mixing device according to claim 1, characterized in that: The central connection assembly (202) includes a connection shell (202a), the bottom of which is connected to the driver (301) via a connection shaft (206), and the side wall of the connection shell (202a) is provided with at least two mounting slots (202e). Each of the two sets of rocker arms (207) has a plug (207a) at one end connected to the central connecting component (202). The shape of the plug (207a) matches the mounting slot (202e). The two sets of rocker arms (207) are connected and fixed to the central connecting component (202) by inserting the plug (207a) into the corresponding mounting slot (202e).

3. The vaccine shaking device according to claim 2, characterized in that: The connecting shell (202a) has a movable groove (202b) at the top inside. The movable groove (202b) has several sliding grooves (202c) around its perimeter. A movable component (204) is disposed in the movable groove (202b). The movable component (204) has several through holes (204b) around its perimeter that correspond to the sliding grooves (202c). An elastic insertion component (203) is disposed on the movable component (204). The elastic insertion component (203) includes several insertion rods (203a) that are inserted into the through holes (204b). The insert (207a) has a mounting hole (207b). When the insert (207a) is inserted into the corresponding mounting slot (202e), the mounting hole (207b) corresponds to the sliding groove (202c) and the insert rod (203a) in the connecting shell (202a).

4. The vaccine mixing device according to claim 3, characterized in that: The movable component (204) includes a movable plate (204a), which has a plurality of through holes (204b) around its perimeter. A connecting block (204c) is fixedly connected to the center of the movable plate (204a). The connecting block (204c) extends to the outside of the connecting shell (202a) and has a pull ring (204d) at its top.

5. The vaccine shaking device according to claim 4, characterized in that: The elastic insert assembly (203) also includes several baffles (203b) and springs (203c). The baffles (203b) and springs (203c) are installed above the movable plate (204a). The top end of the insert rod (203a) is fixedly connected to the bottom of the baffle (203b), and the spring (203c) is fixed above the baffle (203b).

6. The vaccine mixing device according to claim 3, characterized in that: The insert (207a) has a hollow structure, and the two sets of rocker arms (207) have flow grooves (207d) inside. The insert (207a) is connected to the clamping mechanism through the flow grooves (207d). A plurality of sliding grooves (202c) are connected to air holes (202d) at their lower ends, and a sealing assembly (205) is snapped into the lower end of the connecting shell (202a). The air holes (202d) are connected to the sealing assembly (205); and A fan (302) is disposed below the driver (301), and the fan (302) is connected to the air hole (202d) through a sealing assembly (205).

7. The vaccine mixing device according to claim 6, characterized in that: The sealing assembly (205) includes a second bearing (205a), inside which is a connecting ring (205b). The connecting ring (205b) has several connecting holes (205c). The connecting ring (205b) is engaged in the air hole (202d). The second bearing (205a) is engaged in the body (100). The connecting holes (205c) are connected to the air hole (202d).

8. The vaccine mixing device according to claim 6, characterized in that: The bottom of the body (100) is provided with a first conduit (303), and four suction cups (305) are provided at the four corners of the bottom of the body (100). The air inlet of the fan (302) is connected to the first conduit (303), and the first conduit (303) is connected to the four suction cups (305) respectively.

9. The vaccine mixing device according to claim 1, characterized in that: The clamping mechanism includes an arc-shaped first clamping plate (207g) and a second clamping plate (207j). The two sides of the first clamping plate (207g) and the second clamping plate (207j) are connected by a telescopic tube (207h). A return spring is provided outside the telescopic tube (207h). An adsorption groove (207k) is provided in both the first clamping plate (207g) and the second clamping plate (207j). The adsorption groove (207k) is connected to the flow groove (207d) in the two sets of rocker arms (207).

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