A soft antenna for digestive tract tumor ablation with negative pressure positioning

Abstract

The present invention discloses a soft antenna for digestive tract tumor ablation with negative pressure positioning, which relates to the field of medical devices and is composed of a cavity component, a mounting frame, a laparoscope, an input component, and mounting screws. The present invention has a reasonable design, a simple structure, and is easy to use. Through the vacuum suction function of the cavity at the front end of the soft antenna, the vacuum negative pressure is used to attract the tumor tissue into the cavity and contact it with the ablation electrode on the cavity. The high-voltage electric pulse electric field is then transmitted to the target tumor tissue through the ablation electrode, thereby achieving high-voltage steep pulse ablation of the tumor tissue of the digestive tract cavity organ; and a temperature measuring probe is provided in the cavity at the front end of the soft antenna, which has the function of detecting the temperature of the tumor tissue, and can effectively avoid over-ablation caused by the high-voltage steep pulse and cause thermal ablation of the tumor tissue.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a soft antenna with negative pressure positioning for ablation of digestive tract tumors. Background Art

[0002] High-voltage steep pulse tumor ablation is a novel tumor ablation technique. It uses two parallel ablation electrodes attached to two parallel ablation needles to deliver high-voltage pulses to tumor cells, causing irreversible electroporation of the cell membrane at the nanoscale, disrupting the intracellular balance and leading to cell apoptosis. Following apoptosis, phagocytes in the body devour the cell fragments, and the treated area is gradually replaced by normal tissue.

[0003] Existing high-voltage steep-pulse ablation needles consist of a needle body, a handle, an electrode input lead, and a plug. The needle body is typically constructed from a conductive medical stainless steel round tube, covered with an insulating sleeve. The front end of the tube, exposed from the insulating sleeve, serves as the discharge electrode. The tip of the needle is pointed, allowing for percutaneous puncture.

[0004] During high-voltage steep pulse ablation surgery, two parallel ablation needles need to be inserted. The ablation discharge electrode of one ablation needle serves as the positive electrode, while the other serves as the negative electrode. A pulse voltage is input between the two electrodes to perform discharge ablation on the tumor tissue between the two discharge electrodes.

[0005] Currently, in the field of high-pressure steep pulse tumor ablation, tumors are typically ablated via percutaneous puncture with an ablation needle. Therefore, traditional tumor ablation can only be used for solid organ tumors, such as liver, lung, and thyroid tumors. However, it is unable to treat tumors of the digestive tract, such as esophageal cancer, gastric cancer, and colorectal cancer, which have very high incidence rates. Furthermore, existing high-pressure steep pulse ablation needles lack negative pressure suction, limiting the range of impact on tumor tissue and resulting in poor pulse ablation effectiveness. Furthermore, existing high-pressure steep pulse ablation needles lack temperature measurement, making it prone to over-ablation due to the high-pressure steep pulse, leading to thermal ablation of tumor tissue. Summary of the Invention

[0006] The purpose of the present invention is to provide a soft antenna for gastrointestinal tumor ablation with negative pressure positioning, which is used to solve the technical problems in the existing technology that traditional tumor ablation is not conducive to entering the digestive tract, is not convenient for ablating tumors of hollow organs of the digestive tract such as esophageal cancer, gastric cancer, colorectal cancer, etc., has poor pulse ablation effect of tumor tissue, and is prone to over-ablation due to high-voltage steep pulses, resulting in thermal ablation of tumor tissue.

[0007] In order to achieve the above object, the present invention adopts the following technical solutions:

[0008] A soft antenna for digestive tract tumor ablation with negative pressure positioning, consisting of a cavity assembly, a mounting frame, a laparoscope, an input assembly, and mounting screws. The cavity assembly includes: a cavity, which is generally in the shape of a rectangular box, hollow inside, open at the bottom, with a streamlined round head at the front end, two through-holes on the rear end, and U-shaped grooves on both the left and right sides of the open bottom. The U-shaped grooves are distributed inside and outside the cavity, and an exhaust channel for negative pressure suction is provided in the rear end of the cavity; a positive electrode is installed in the U-shaped groove on the left side and is flush with the outer surface of the cavity; The negative electrode is installed in the U-shaped groove on the right side and is flush with the outer surface of the cavity; the filter is a filter element with an extremely fine mesh and is installed in a through exhaust channel on the rear end face of the cavity; the sealing ring is in a ring shape, and its outer ring is tightly matched with the small hole in the cavity; the input component includes: a positive wire, one end of which is connected to the positive electrode; a negative wire, one end of which is connected to the negative electrode; a negative pressure air pipe, the front end of which is installed in the sealing ring at the rear end of the cavity, protruding from the front end of the sealing ring, and tightly matched with the sealing ring; an air pipe plug, one end of which is connected to the end of the negative pressure air pipe to achieve a tight fit in the air path.

[0009] Preferably, a circular hole is provided in the middle of the rear end of the mounting bracket, the cavity mirror is installed in the circular hole, a small through hole is provided on the outside of the mounting bracket, and the input component passes through the small hole; the end face of the rear end of the cavity component is provided with threaded holes around it, and the front end of the mounting bracket has corresponding through holes, and the mounting bracket and the cavity component are connected into one by the mounting screws.

[0010] Preferably, the cavity assembly also includes: a temperature measuring mounting sleeve, which is cylindrical with a step and has a non-through hole at its center, and the temperature measuring mounting sleeve is installed in another through hole on the rear end face of the cavity; an isolation retaining ring, which is ring-shaped and is installed together with the filter in the same through hole of the cavity and is tightly attached to the rear end face of the filter; the front end face of the sealing ring is installed tightly against the rear end of the isolation retaining ring.

[0011] Preferably, the input component includes: a positive wire insulation layer, which is sleeved on the positive wire; a negative wire insulation layer, which is sleeved on the negative wire; a temperature measuring probe, which is a short cylindrical shape, installed in the center hole of the temperature measuring installation sleeve, and its front end face is close to the inner end face of the center hole, for accurately sensing the temperature of the tissue in the cavity; a temperature measuring optical fiber, which is an extremely fine optical fiber material, the front end of which is connected to the temperature measuring probe to realize optical fiber detection and transmission of temperature; a sheath tube, which is a slender soft sleeve with a middle hole, and the positive wire, the positive wire insulation layer, the negative wire, the negative wire insulation layer and the temperature measuring optical fiber are connected to the positive wire, the negative wire, the negative wire insulation layer and the temperature measuring optical fiber. and the negative pressure air pipe are all arranged in the sheath tube, and the positive wire, the positive wire insulation layer, the negative wire, the negative wire insulation layer and the temperature measuring optical fiber and the front and rear ends of the negative pressure air pipe are respectively exposed from the sheath tube; the positive electrode plug, the rear end of the plug is electrically connected to the positive wire to realize electrical transmission; the negative electrode plug, the rear end of the plug is electrically connected to the negative wire to realize electrical transmission; the temperature measuring plug is a cylinder with a microhole in the middle, and the tail end of the temperature measuring optical fiber is installed in the temperature measuring plug; the plug body, the air pipe plug, the positive electrode plug, the negative electrode plug and the temperature measuring plug are all installed in it.

[0012] Preferably, the front end surface of the mounting frame is provided with a groove for installing and fixing the positive wire, the positive wire insulation layer, the negative wire and the negative wire insulation layer and the negative pressure air pipe, and the outer surface of the front end of the positive electrode and the negative electrode is slightly higher than the front end surface of the mounting frame.

[0013] Preferably, the height of the U-shaped groove inside the cavity is greater than the height of the U-shaped groove outside the cavity.

[0014] Preferably, the positive wire and the negative wire are both in the shape of an elongated cylinder; and the negative pressure air pipe is a elongated stainless steel pipe.

[0015] Preferably, the temperature measuring mounting sleeve is made of stainless steel; the isolation retaining ring is made of polytetrafluoroethylene; and the sealing ring is made of silicone.

[0016] Preferably, the sheath tube is made of polytetrafluoroethylene material; the temperature measuring plug is made of ceramic material.

[0017] Preferably, the cavity and the mounting frame are both made of highly transparent polypropylene material.

[0018] To sum up, due to the adoption of the above-mentioned technical scheme, the beneficial effects of the present invention are: the device is reasonably designed, simple in structure, and easy to use. Through the vacuum suction function of the cavity at the front end of the soft antenna, the tumor tissue is attracted into the cavity by utilizing the vacuum negative pressure and contacts with the ablation electrode on the cavity, and then the high-voltage electric pulse electric field is transmitted to the target tumor tissue through the ablation electrode, thereby realizing high-voltage steep pulse ablation of the tumor tissue of the hollow organs of the digestive tract; and there is a temperature measuring probe in the cavity at the front end of the soft antenna, which has the function of detecting the temperature of the tumor tissue, which can effectively avoid over-ablation caused by high-voltage steep pulses and cause thermal ablation of the tumor tissue. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a front view schematic diagram of the structure of the present invention.

[0020] Figure 2 It is a bottom view schematic diagram of the structure of the present invention.

[0021] Figure 3 yes Figure 1 Enlarged cross-sectional view at YY in the middle.

[0022] Figure 4 yes Figure 1 Enlarged cross-sectional view at TT in the middle.

[0023] Figure 5 yes Figure 4 Enlarged cross-sectional view at PP in the middle.

[0024] Figure 6 yes Figure 2 Enlarged cross-sectional view at VV in the middle.

[0025] Figure 7 yes Figure 2 Enlarged cross-sectional view at KK in the middle.

[0026] Figure 8 yes Figure 7 Enlarged cross-sectional view at point G in the middle.

[0027] Figure 9 yes Figure 2 Enlarged cross-sectional view at LL.

[0028] Figure 10 yes Figure 9 Enlarged cross-sectional view at point F in the middle.

[0029] Figure 11 yes Figure 2 Enlarged cross-sectional view at XX in the middle.

[0030] Figure numerals: 1. cavity assembly; 2. mounting bracket; 3. cavity mirror; 4. input assembly; 5. mounting screw; 6. cavity; 7. positive electrode; 8. negative electrode; 9. filter; 10. temperature measuring mounting sleeve; 11. isolation retaining ring; 12. sealing ring; 13. positive wire; 14. positive wire insulation layer; 15. negative wire; 16. negative wire insulation layer; 17. temperature measuring probe; 18. temperature measuring optical fiber; 19. negative pressure air pipe; 20. sheath tube; 21. air pipe plug; 22. positive electrode plug; 23. negative electrode plug; 24. temperature measuring plug; 25. plug body. DETAILED DESCRIPTION

[0031] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific embodiments and drawings. However, the following embodiments are only preferred embodiments of the present invention and are not exhaustive. Based on the embodiments in the implementation manner, other embodiments obtained by those skilled in the art without making any creative work are all within the scope of protection of the present invention.

[0032] Specific embodiments of the present invention are described below with reference to the accompanying drawings.

[0033] Example, such as Figure 1-Figure 2 、 Figure 4 and Figure 9 As shown, a soft antenna for digestive tract tumor ablation with negative pressure positioning is composed of a cavity component 1, a mounting frame 2, a laparoscope 3, an input component 4 and a mounting screw 5.

[0034] like Figure 1 and Figure 3 As shown, the cavity 6 is in the shape of a rectangular box, which is hollow inside and open at the bottom; the front end is a streamlined round head for easy entry into the digestive tract; the rear end has two small holes through it; there is a U-shaped groove on each side of the left and right sides of the open bottom position, each distributed inside and outside the cavity 6, and the height of the U-shaped groove inside the cavity 6 is greater than the height of the U-shaped groove outside the cavity 6.

[0035] like Figure 1 and Figure 3 As shown, the shapes of the positive and negative electrodes 7 and 8 match the U-shaped grooves of the cavity 6. They are installed in the left and right U-shaped grooves, respectively, and are flush with the outer surface of the cavity 6. The cavity 6 is made of an insulating transparent material, and in this embodiment, a medical-grade, highly transparent polypropylene polymer is used. The positive and negative electrodes 7 and 8 are both made of a thin conductive sheet, and in this embodiment, a medical-grade 316L stainless steel sheet with a thickness of 0.2 mm. The laparoscope 3 is a purchased part with an outer diameter of 9 mm.

[0036] like Figure 3 、 Figure 6 and Figure 8 As shown, the filter 9 is a filter element with an extremely fine mesh; it is installed in a through hole on the rear end surface of the cavity 6.

[0037] like Figure 8 As shown, the isolation retaining ring 11 is made of polytetrafluoroethylene material and is in a ring shape. It is installed together with the filter 9 in the same through hole of the cavity 6 and is tightly attached to the rear end surface of the filter 9.

[0038] like Figure 8 As shown, the sealing ring 12 is made of silicone material and is in a ring shape. The front end surface is installed tightly against the rear end of the isolation retaining ring 11, and the outer ring is tightly matched with the small hole of the cavity 6.

[0039] like Figure 3 and Figure 6 As shown, the temperature measuring sleeve 10 is installed in another through hole on the rear end surface of the cavity 6. The temperature measuring sleeve 10 is made of 316L stainless steel with high thermal conductivity, is cylindrical with a step, and has a non-through hole in the center.

[0040] like Figure 3-Figure 8 and Figure 10-11 As shown, the input component 4 includes a positive wire 13, a positive wire insulation layer 14, a negative wire 15, a negative wire insulation layer 16, a temperature measuring probe 17, a temperature measuring optical fiber 18, a negative pressure air pipe 19, a sheath tube 20, an air pipe plug 21, a positive electrode plug 22, a negative electrode plug 23, a temperature measuring plug 24 and a plug body 25.

[0041] The negative pressure air pipe 19 is made of a slender 316L stainless steel pipe with an outer diameter of 0.5 and an inner hole of 0.3 mm. The front end is installed in the sealing ring 12 at the rear end of the cavity 6, and the front end of the sealing ring 12 is exposed and tightly fitted with the sealing ring 12.

[0042] The positive wire 13 and the negative wire 15 are both in the shape of an elongated cylinder and are made of highly conductive materials. In this embodiment, the positive wire 13 and the negative wire 15 are made of silver-plated copper wire with a wire diameter of 0.2 mm.

[0043] like Figure 10 As shown, the outer peripheries of the positive wire 13 and the negative wire 15 except for the two ends are respectively covered with a positive wire insulation layer 14 and a negative wire insulation layer 16 .

[0044] The positive wire insulation layer 14 and the negative wire insulation layer 16 are both high-voltage resistant insulation sleeves. In this embodiment, they are made of polyimide polymer material.

[0045] like Figure 6As shown, the temperature measuring probe 17 is a short cylindrical shape and is installed in the center hole of the temperature measuring mounting sleeve 10, with its front end face close to the inner end face of the center hole; this embodiment uses an optical fiber temperature measuring probe, which is a purchased part.

[0046] like Figure 6 As shown, the temperature measuring optical fiber 18 is an extremely thin optical fiber material. In this embodiment, its outer diameter is 0.1 mm. Its front end is connected to the temperature measuring probe 17 to realize optical fiber detection and transmission of temperature.

[0047] like Figure 10 As shown, the sheath tube 20 is a slender, soft, through-hole sheath made of polytetrafluoroethylene, and the front and rear ends of the positive wire 13, the positive wire insulation layer 14, the negative wire 15, the negative wire insulation layer 16, the temperature measuring optical fiber 18 and the negative pressure air pipe 19 are respectively exposed from the sheath tube 20.

[0048] like Figure 1-Figure 2 and Figure 4 As shown, the front end of the input component 4 passes through another small hole of the mounting frame 2 that runs through the entire mounting frame 2, wherein the positive wire 13, the positive wire insulation layer 14, the negative wire 15, the negative wire insulation layer 16 and the negative pressure air pipe 19 are fixedly installed in the groove on the front end surface of the mounting frame 2.

[0049] like Figure 9 As shown, the mounting frame 2 is made of insulating transparent polypropylene material; there is a circular hole in the middle of the tail end, and the cavity mirror 3 is installed in the circular hole; there is a through small hole on the outside, and the input component 4 passes through it; at the front end, there are four small holes on the outer periphery, which can be connected to the cavity component 1 into one by installing screws 5.

[0050] like Figure 3-Figure 4 As shown, the positive electrode 7 and the negative electrode 8 on the two long sides of the cavity 6 extend all the way to the rear end face of the cavity 6; by tightening the mounting screws 5, the positive wire 13 and the negative wire 15 in the groove on the front end face of the mounting frame 2 are respectively connected to the positive electrode 7 and the negative electrode 8 on the rear end face of the cavity 6 to achieve reliable electrical connection.

[0051] like Figure 1 、 Figure 6-Figure 8 As shown, the cavity 6 at the rear end of the cavity assembly 1 has an exhaust channel for negative pressure suction and an anti-clogging filtering device, which is a filter 9.

[0052] like Figure 6 As shown, there is a temperature measuring sleeve 10 with fast heat conduction in the cavity 6 at the rear end of the cavity assembly 1, and the temperature measuring sleeve 10 is installed in the rear end surface of the cavity 6 and exposes the inner surface of the cavity 6. The temperature measuring probe 17 is installed therein, which can accurately sense the temperature of the tissue in the cavity 6.

[0053] like Figure 10-11 As shown, the plug body 25 is a plastic part, in which the tracheal plug 21, the positive electrode plug 22, the negative electrode plug 23 and the temperature measuring plug 24 are all installed; the positive electrode plug 22 and the negative electrode plug 23 are both made of conductive materials, and the rear ends of the plugs are electrically connected to the positive wire 13 and the negative wire 15 respectively to achieve electrical transmission; the temperature measuring plug 24 is a cylinder with a micropore in the middle, and the material is a ceramic part. In this embodiment, zirconia ceramic is used, and its inner hole is 0.125 mm. The tail end of the temperature measuring optical fiber 18 is installed therein; the tracheal plug 21 is a dedicated air circuit plug, which is a purchased part. Its front end and the tail end of the negative pressure air pipe 19 can achieve a tight fit in the air circuit.

[0054] The present invention uses the vacuum suction function of the cavity 6 at the front end of the soft antenna to utilize vacuum negative pressure to attract tumor tissue into the cavity 6, contact it with the ablation electrode on the cavity 6, and then transmit the high-voltage electric pulse electric field to the target tumor tissue through the ablation electrode, thereby realizing high-voltage steep pulse ablation of tumor tissue in the hollow organ; at the same time, there is a temperature measuring probe 17 in the cavity 6 at the front end of the soft antenna, which has the function of detecting the temperature of the ablated tumor tissue, and can effectively avoid over-ablation caused by high-voltage steep pulses and cause thermal ablation of the tumor tissue.

[0055] The above description is only a preferred specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any technician familiar with the technical field, within the technical scope disclosed by the present invention, who makes equivalent replacements or changes based on the technical solution and inventive concept of the present invention, should be covered by the scope of protection of the present invention.

[0056] The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. These preferred embodiments do not exhaustively describe all details, nor do they limit the present invention to specific embodiments. Obviously, many modifications and variations are possible based on the contents of this specification. These embodiments are selected and described in detail in this specification to better explain the principles and practical applications of the present invention, thereby enabling those skilled in the art to better understand and utilize the present invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A soft antenna for digestive tract tumor ablation with negative pressure positioning, consisting of a cavity assembly, a mounting frame, a laparoscope, an input assembly and mounting screws, characterized in that , The chamber assembly includes: The cavity is a rectangular box with a hollow interior and an open bottom. The front end is a streamlined round head, and the rear end has two through-holes. U-shaped grooves are provided on both sides of the open bottom. The U-shaped grooves are distributed inside and outside the cavity. An exhaust channel for negative pressure suction is provided in the rear end of the cavity. The positive electrode is installed in the U-shaped groove on the left side and is flush with the outer surface of the cavity; The negative electrode is installed in the U-shaped groove on the right side and is flush with the outer surface of the cavity; The filter is a filter element with an extremely fine mesh and is installed in a through exhaust channel on the rear end face of the cavity; The sealing ring is in the shape of a ring, and its outer ring fits tightly with the small hole of the cavity; Input components include: A positive wire, one end of which is connected to the positive electrode; a negative wire, one end of which is connected to the negative electrode; The front end of the negative pressure air pipe is installed in the sealing ring at the rear end of the cavity, protrudes from the front end of the sealing ring, and fits tightly with the sealing ring; Tracheal plug, one end of which is connected to the end of the negative pressure trachea to achieve a tight fit of the air path; The input component also includes: A positive conductor insulation layer is provided on the positive conductor; A negative conductor insulation layer is sleeved on the negative conductor; The temperature probe is a short cylindrical body installed in the center hole of the temperature measuring sleeve, with its front end close to the inner end surface of the center hole, and is used to accurately sense the temperature of the tissue in the cavity; The temperature measuring optical fiber is an extremely thin optical fiber material, the front end of which is connected to the temperature measuring probe to realize the optical fiber detection and transmission of temperature; The sheath tube is a slender, middle-through soft sheath tube, in which the positive wire, the positive wire insulation layer, the negative wire, the negative wire insulation layer, the temperature measuring optical fiber, and the negative pressure air pipe are all arranged, and the front and rear ends of the positive wire, the positive wire insulation layer, the negative wire, the negative wire insulation layer, the temperature measuring optical fiber, and the negative pressure air pipe are respectively exposed from the sheath tube; The positive electrode plug, the rear end of which is electrically connected to the positive wire to achieve electrical transmission; The negative electrode plug, the rear end of which is electrically connected to the negative wire to achieve electrical transmission; The temperature measuring plug is a cylinder with a microhole in the middle. The temperature measuring plug is made of zirconia ceramic material. Its inner hole is 0.125 mm. The tail end of the temperature measuring optical fiber is installed in the temperature measuring plug. The plug body, the air pipe plug, the positive electrode plug, the negative electrode plug and the temperature measuring plug are all installed therein.

2. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 1, characterized in that: A circular hole is set in the middle of the rear end of the mounting bracket, and the cavity mirror is installed in the circular hole. There is a small through hole on the outside of the mounting bracket, and the input component passes through the small hole; the end face of the rear end of the cavity component is surrounded by threaded holes, and the front end of the mounting bracket has corresponding through holes. The mounting bracket and the cavity component are connected into one by installing screws.

3. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 2, characterized in that: The cavity assembly also includes: The temperature measuring installation sleeve is cylindrical with a step and has a small non-through hole at its center. The temperature measuring installation sleeve is installed in another through hole on the rear end face of the cavity. The isolation retaining ring is in a ring shape and is installed together with the filter in the same through hole of the cavity and is tightly attached to the rear end face of the filter; the front end face of the sealing ring is installed tightly to the rear end of the isolation retaining ring.

4. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 2, characterized in that: The front end surface of the mounting frame is provided with grooves for installing and fixing the positive wire, the positive wire insulation layer, the negative wire and the negative wire insulation layer, and the negative pressure air pipe. The outer surfaces of the front end of the positive electrode and the negative electrode are slightly higher than the front end surface of the mounting frame.

5. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 1, characterized in that: The height of the U-shaped groove inside the cavity is greater than the height of the U-shaped groove outside the cavity.

6. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 3, characterized in that: The positive wire and the negative wire are both in the shape of a slender cylinder; the negative pressure air pipe is a slender stainless steel pipe.

7. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 6, characterized in that: The temperature measuring installation sleeve is made of stainless steel; the isolation retaining ring is made of polytetrafluoroethylene; and the sealing ring is made of silicone.

8. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 1, characterized in that: The sheath tube is made of polytetrafluoroethylene material.

9. The soft antenna for digestive tract tumor ablation with negative pressure positioning according to claim 1 or 2, characterized in that: The cavity and mounting frame are made of highly transparent polypropylene material.

Images