Sunscreen composition and use thereof, daily necessities

Abstract

The application belongs to the technical field of cosmetic production and discloses a sunscreen composition which comprises bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazone and diethyl amino hydroxybenzoyl hexyl benzoate in a mass ratio of 1-2:1-2:1-2, and at least one of the bis-ethylhexyloxyphenol methoxyphenyl triazine, the ethylhexyl triazone and the diethyl amino hydroxybenzoyl hexyl benzoate is coated with a shell structure, and the shell structure is prepared by mixing polymethylsilsesquioxane, lauroyl lysine, HDI / trihydroxymethyl hexyl lactone crosslinking polymer, dimethicone and triethoxysilane, so that the oil dispersibility and water dispersibility of the sunscreen composition are improved, the sunscreen performance of the sunscreen composition is improved to a certain extent, and the application of the sunscreen composition and a daily chemical product are disclosed.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of daily chemical production, and particularly relates to a sunscreen composition and application thereof, and a daily chemical product. BACKGROUND

[0002] Sunscreen is a chemical substance that can improve the sunscreen effect of sunscreen products. With the increasing awareness of the harm of ultraviolet rays, the importance of sunscreen products in daily skin care has also been gradually valued by people. The emergence of sunscreen provides more choices and improvements for the effect of sunscreen products. The main function of sunscreen is to increase the absorption capacity of sunscreen products to ultraviolet rays, prolong the sunscreen time, and improve the sunscreen index. They can protect the skin from ultraviolet damage by absorbing, reflecting or scattering ultraviolet rays.

[0003] Organic ultraviolet absorber is a common sunscreen. They can absorb ultraviolet rays and convert them into heat energy, thereby protecting the skin from ultraviolet damage. Common organic ultraviolet absorbers include oxybenzone, benzophenone, etc. These compounds have good ultraviolet absorption performance and can stably exist in sunscreen products without being easily decomposed. Nanoparticles are also a common sunscreen. Nanoparticles such as titanium dioxide and zinc oxide have high ultraviolet absorption capacity and can reflect or scatter ultraviolet rays, effectively blocking the invasion of ultraviolet rays. The small size of nanoparticles enables them to be uniformly dispersed in sunscreen products, improving the spreadability and transparency of sunscreen products. Antioxidants are also widely used as sunscreen in sunscreen products. Ultraviolet radiation produces a large number of free radicals, causing oxidative damage to skin cells. Antioxidants such as vitamin C, vitamin E, etc. can neutralize free radicals, reduce oxidative damage caused by ultraviolet rays, and protect the skin from ultraviolet damage. At the same time, antioxidants can also improve the stability of sunscreen products and prolong their service life.

[0004] In addition, some anti-inflammatory agents are also used as sunscreen. Ultraviolet radiation can cause inflammatory reactions in the skin, resulting in skin redness, itching and other uncomfortable symptoms. Anti-inflammatory agents such as glycyrrhizic acid, green tea extract, etc. can inhibit inflammatory reactions and reduce skin discomfort caused by ultraviolet rays. In summary, sunscreen is a class of chemical substances that can improve the sunscreen effect of sunscreen products. They can increase the absorption capacity of sunscreen products to ultraviolet rays, prolong the sunscreen time, improve the sunscreen index, etc. Organic ultraviolet absorbers, nanoparticles, antioxidants and anti-inflammatory agents are common sunscreens. Their application makes sunscreen products safer, more effective, and better protects the skin from ultraviolet damage.

[0005] Chinese patent application 202310462255.9 discloses a highly effective sunscreen synergist and sunscreen agent and its preparation method. The highly effective sunscreen synergist includes flavonoids, plant extracts, copolymers and cellulose; wherein the flavonoids include one of trox, rutin, quercetin, rotenone and catechin.

[0006] Plant extracts include one or both of Magnolia biondii flower extract and Magnolia biondii bark extract;

[0007] The copolymer is an acrylate copolymer;

[0008] Cellulose includes one or more of microcrystalline cellulose, ethyl cellulose, and sea squirt cellulose;

[0009] This solution enhances the sun protection performance of sunscreens by adding sunscreen synergists, which work in conjunction with other substances in the sunscreen to improve its SPF. It also improves the user experience by adding troxerutin, magnolia flower extract, acrylate copolymers, and microcrystalline cellulose. Furthermore, it enhances the water resistance of sunscreens by combining lipid emulsifiers such as polyglycerol-6 stearate and polyglycerol-behenate, potassium cetyl phosphate, and inulin lauryl carbamate with microcrystalline cellulose and acrylate copolymers. This results in sunscreens with added synergists that offer both moisturizing and soothing effects, high SPF, and low irritation, while also providing some moisturizing and redness-repairing benefits. However, this solution does not delve into the structural design of the sunscreen synergists.

[0010] Chinese patent application 202110115890.0 discloses a sunscreen composition and a sunscreen emulsion composed therefrom, the sunscreen composition comprising the following components: 26-30 parts of ethylhexyl methoxycinnamate; 6-10 parts of diethylamino hydroxybenzoyl hexyl benzoate; and 3-5 parts of ethylhexyl triazine ketone.

[0011] This method involves compounding ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate, and ethylhexyl triazine ketone in specific weight proportions to create a coated sunscreen composition. This composition can significantly reduce the amount of sunscreen agent used. Compared to a combination of sunscreen agents with the same content but not in a coated state, it can improve sun protection performance by 40-60% while significantly reducing skin irritation. When added to sunscreen lotion formulations and compounded with specific amounts of emollients, emulsifiers, thickeners, common sunscreen agents, skin conditioning agents, moisturizers, preservatives, and antioxidants, the resulting sunscreen lotion can significantly reduce skin irritation and has significantly improved gentleness while maintaining a high SPF value.

[0012] This formulation combines ethylhexyl methoxycinnamate, diethylaminobenzoylhexyl benzoate, and ethylhexyl triazine ketone, and then encapsulates these compounds using a mixture of glyceryl stearate, stearyl alcohol polyether-21, stearyl alcohol polyether-2, glycerin, hydrogenated castor oil, phenoxyethanol, methylparaben, propylparaben, and water, resulting in a encapsulated sunscreen composition. This encapsulated sunscreen composition significantly reduces the amount of sunscreen agent required and provides a 40-60% improvement in sun protection performance compared to sunscreen combinations with the same content but in an unencapsulated state. While increasing the concentration, it can significantly reduce skin irritation. Furthermore, observation of the embodiments and comparative data of this scheme shows that even without changing the amount of other substances added, simply altering the ratio of ethylhexyl methoxycinnamate, hexyl diethylamino hydroxybenzoyl benzoate, and ethylhexyl triazine ketone in the core structure cannot solve the problem this scheme aims to address. Similarly, when ethylhexyl triazine ketone is missing from the core structure, this scheme cannot solve the problem; and when both hexyl diethylamino hydroxybenzoyl benzoate and ethylhexyl triazine ketone are missing from the core structure, this scheme cannot solve the problem.

[0013] This shows that solving the problem requires not only obtaining a coated sunscreen composition, but also careful selection of the core material and the proportions of each component. However, observing the basic formula of the scheme, "The sunscreen composition includes the following components: 26-30 parts of ethylhexyl methoxycinnamate; 6-10 parts of diethylamino hydroxybenzoyl hexyl benzoate; 3-5 parts of ethylhexyl triazine ketone," reveals that the selection of the shell material is far less important than the selection of the core material. Furthermore, the main purpose of the coated sunscreen composition prepared by this scheme is to reduce the sunscreen's SPF value and its skin irritation; however, this scheme does not focus on the dispersibility of the sunscreen composition within the sunscreen.

[0014] The problem this solution aims to solve is: how to develop a sunscreen composition with a core-shell structure to improve its dispersibility and sun protection capabilities as a sunscreen composition. Summary of the Invention

[0015] The purpose of this invention is to provide a sunscreen composition with a core-shell structure. Through the synergistic effect of the shell structure and the core structure, the oil dispersibility and water dispersibility of the sunscreen composition are improved, and the sunscreen performance of the sunscreen composition is improved to a certain extent.

[0016] To achieve the above objectives, this application discloses a sunscreen composition comprising bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate in a mass ratio of 1-2:1-2:1-2, wherein at least one of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate is coated with a shell structure, wherein the shell structure is prepared by mixing polymethylsilsesquioxane, lauroyl lysine, HDI / trimethylolhexyl lactone crosspolymer, polydimethylsiloxane, and triethoxyoctylsilane;

[0017] Furthermore, the amount of each component added in the shell structure is as follows:

[0018]

[0019] Preferably, in the shell structure, the amount of each component added is:

[0020]

[0021] Preferably, the mass ratio of the shell structure to the bis-ethylhexyloxyphenol methoxyphenyl triazine and / or ethylhexyl triazine ketone and / or diethylaminohydroxybenzoyl hexyl benzoate encapsulated within the shell structure is 48–52:48–52.

[0022] In addition, this application also discloses a method for preparing a sunscreen composition, wherein the method for preparing the sunscreen composition is as follows: a shell structure is prepared by mixing polymethylsilsesquioxane, lauroyl lysine, HDI / trimethylolhexyl lactone crosspolymer, polydimethylsiloxane, and triethoxyoctylsilane; the shell structure is coated on the surface of at least one of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylaminohydroxybenzoyl hexyl benzoate; and then the bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylaminohydroxybenzoyl hexyl benzoate are mixed to obtain the sunscreen composition.

[0023] In addition, this application also discloses the use of the sunscreen composition described above as an active ingredient in sunscreen daily chemical products.

[0024] In addition, this application also discloses a sunscreen daily chemical product containing the above-mentioned sunscreen composition.

[0025] Preferably, the sunscreen is in the form of a cream, lotion, or spray.

[0026] The beneficial effects of this application are:

[0027] This application uses a shell structure prepared by mixing polymethylsilsesquioxane, lauroyl lysine, HDI / trimethylolhexyl lactone crosspolymer, polydimethylsiloxane, and triethoxyoctylsilane to coat the surface of at least one of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate. Subsequently, the three are mixed together. This design makes the composition smoother on the skin and easier to disperse with oils, while improving the oil dispersibility and water dispersibility of the sunscreen composition, and also improving the sun protection performance of the sunscreen composition to a certain extent. Detailed Implementation

[0028] The present invention will now be clearly and completely described in conjunction with embodiments thereof. It should be noted that, unless specific conditions are specified in the embodiments, conventional conditions or conditions recommended by the manufacturer shall apply. Reagents or instruments whose manufacturers are not specified are all commercially available conventional products.

[0029] Information on the raw materials for each example is shown in Table 1:

[0030] Table 1

[0031]

[0032]

[0033] Preparation method of sunscreen composition:

[0034] Step 1: Weigh out polymethylsilsesquioxane, lauroyl lysine, HDI / trimethylolhexyl lactone crosspolymer, polydimethylsiloxane, and triethoxyoctylsilane according to the amount of shell structure material added in the formula. Then, put the above raw materials into a beaker containing deionized water and ultrasonically disperse for 30 minutes to obtain a dispersion.

[0035] Step 2: The coated material is placed in dispersion 1, heated in a water bath at 80°C for 3 hours, and dried to obtain the coated bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, or diethylaminohydroxybenzoyl hexyl benzoate; it should be noted that the specific coated material is described in the examples.

[0036] Step 3: Mix the coated bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, or diethylamino hydroxybenzoyl hexyl benzoate with the uncoated bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, or diethylamino hydroxybenzoyl hexyl benzoate to obtain a sunscreen composition.

[0037] Examples 1-4

[0038] A sunscreen composition, the formulation of which has a shell structure is shown in Table 2:

[0039] Table 2

[0040]

[0041]

[0042] It should be noted that the shell structure prepared in Examples 1-4 is coated on the surface of bis-ethylhexyloxyphenol methoxyphenyl triazine, and the mass ratio of the shell structure to bis-ethylhexyloxyphenol methoxyphenyl triazine is 1:1. Furthermore, the preparation method in Examples 1-4 involves first coating the shell structure onto the surface of bis-ethylhexyloxyphenol methoxyphenyl triazine, and then mixing the coated bis-ethylhexyloxyphenol methoxyphenyl triazine with ethylhexyl triazine ketone and diethylaminohydroxybenzoyl hexyl benzoate. The mass ratio of ethylhexyl triazine ketone, diethylaminohydroxybenzoyl hexyl benzoate, and uncoated bis-ethylhexyloxyphenol methoxyphenyl triazine is 1:1:1.

[0043] Example 5

[0044] The method is basically the same as in Example 1, except that the shell structure is coated on the surface of ethylhexyltriazine ketone, and the mass ratio of bis-ethylhexyloxyphenol methoxyphenyltriazine, diethylaminohydroxybenzoylhexyl benzoate to uncoated ethylhexyltriazine ketone is 1:1:1.

[0045] Example 6

[0046] The method is basically the same as in Example 1, except that the shell structure is coated on the surface of diethylamino hydroxybenzoyl hexyl benzoate, and the mass ratio of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone and uncoated diethylamino hydroxybenzoyl hexyl benzoate is 1:1:1.

[0047] Example 7

[0048] The method is basically the same as in Example 1, except that the shell structure is coated on the surface of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate, respectively, and the total mass ratio of the shell structure to the total mass of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate is 1:1, while the mass ratio of uncoated bis-ethylhexyloxyphenol methoxyphenyl triazine, uncoated ethylhexyl triazine ketone, and uncoated diethylamino hydroxybenzoyl hexyl benzoate is 1:1:1.

[0049] Example 8

[0050] It is basically the same as Example 1, except that the mass ratio of the core structure to the shell structure is 48:52.

[0051] Example 9

[0052] It is basically the same as Example 1, except that the mass ratio of the core structure to the shell structure is 52:48.

[0053] Example 10

[0054] The results are basically the same as in Example 1, except that the mass ratio of uncoated bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate is 1:2:1.

[0055] Example 11

[0056] The results are basically the same as in Example 1, except that the mass ratio of uncoated bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate is 2:1:2.

[0057] Comparative Examples 1-5

[0058] A composition, substantially the same as in Example 1, differs in that the formulation of the shell structure is shown in Table 3:

[0059] Table 3

[0060]

[0061] Comparative Examples 6-10

[0062] A composition, substantially the same as in Example 1, except that the formulation of the shell structure is shown in Table 4:

[0063] Table 4

[0064]

[0065]

[0066] Comparative Example 11

[0067] The method is basically the same as in Example 1, except that ethylhexyl methoxycinnamate is used instead of bis-ethylhexyloxyphenol methoxyphenyl triazine, and the shell structure is coated onto the surface of ethylhexyl methoxycinnamate. At the same time, the mass ratio of uncoated ethylhexyl methoxycinnamate to diethylaminohydroxybenzoylhexyl benzoate and ethylhexyl triazine ketone is 1:1:1.

[0068] Performance testing:

[0069] 1. Dispersion test

[0070] The compositions obtained in the examples and comparative examples were added to aqueous and oil solvents, respectively, and the dispersibility of the compositions in the aqueous and oil phases was tested. The results are shown in Table 5.

[0071] Table 5

[0072]

[0073]

[0074]

[0075] 2. Sunscreen efficacy test

[0076] (1) Sun Protection Factor (SPF): Also known as the Sun Protection Factor, it indicates the level of sun protection effectiveness of sunscreen products; the higher the SPF value, the better the sun protection effect; it is determined based on the minimum erythema dose (MED) of the skin. After using sunscreen products, the minimum erythema dose of the skin will increase, so the SPF of the sunscreen product is: SPF = Minimum Erythema Dose (after using sunscreen products) / Minimum Erythema Dose (before using sunscreen products). The SPF index is used to evaluate the protection effect against UVB.

[0077] (2) Sunscreen cosmetics' long-wave ultraviolet protection index (PFA value): also known as UVA protection index. When sunlight irradiates the skin, UVA mainly produces the physiological effect of skin darkening, which is measured by the minimum sustained darkening dose (MPPD). MPPD is the minimum ultraviolet radiation dose or the shortest irradiation time required to produce slight darkening of the entire irradiated area of ​​skin 2-4 hours after irradiation. The sun protection effect of the products was obtained according to the test examples and comparative proportions of the "Test Method for Sunscreen Cosmetics Sunscreen Index (Human Method)" in the "Cosmetic Safety Technical Specifications" (2015 edition). The test results are shown in Table 6.

[0078] Before testing, the sunscreen compositions prepared in the examples and comparative examples were mixed with the oil phase components to prepare the finished sunscreen agent and tested. The oil phase components included isododecane, diisopropyl sebacate, bis-ethylhexyloxyphenol methoxyphenyl triazine / ethylhexyl triazine ketone / diethylaminohydroxybenzoyl benzoate, C12-15 alcohol benzoate, homosalate, octocrylene, and ethylhexyl methoxycinnamate.

[0079] Table 6: Sunscreen Test Results

[0080]

[0081]

[0082] Results analysis:

[0083] 1. As can be seen from Examples 1-4, when the amount of each composition in the shell layer is changed, the water dispersibility and oil dispersibility of the sunscreen composition do not change significantly, and the sun protection ability of the sunscreen agent prepared subsequently does not fluctuate significantly. However, Example 1 has certain advantages over Examples 2-4 in terms of water dispersibility, oil dispersibility and the sun protection ability of the sunscreen agent prepared subsequently. Therefore, we believe that the ratio of shell layer content in Example 1 is more advantageous than that in Examples 2-4.

[0084] 2. As can be seen from Examples 5-7, when ethylhexyl triazine ketone and diethylamino hydroxybenzoyl hexyl benzoate were used instead of bis-ethylhexyloxyphenol methoxyphenyl triazine as the core structure coated by the shell structure in Examples 5 and 6, the changes in dispersion performance in the three examples were not significant, but the sun protection ability of the sunscreen agent prepared subsequently fluctuated to some extent. Meanwhile, when ethylhexyl triazine ketone, diethylamino hydroxybenzoyl hexyl benzoate, and bis-ethylhexyloxyphenol methoxyphenyl triazine were coated simultaneously in Example 7, the sun protection effect was significantly improved compared to Example 1.

[0085] 3. As can be seen from Example 1 and Comparative Examples 1-5, when any substance in the shell structure is omitted, the dispersibility of the sunscreen itself and the sun protection ability of the subsequently prepared sunscreen are significantly reduced. This shows that any component in the shell structure of the sunscreen composition is indispensable.

[0086] 4. As can be seen from Example 1 and Comparative Examples 6-10, when other substances are used to replace any substance in the shell structure, the dispersibility of the sunscreen itself and the sun protection ability of the subsequently prepared sunscreen are significantly reduced. This shows that no component in the shell structure of the sunscreen composition can be replaced.

[0087] 5. As can be seen from Example 1 and Comparative Example 11, when bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate are replaced with bis-ethylhexyloxyphenol methoxyphenyl triazine, the sunscreen composition still cannot exhibit good sun protection effect.

Claims

1. A sunscreen composition, characterized in that, The sunscreen composition comprises bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate in a mass ratio of 1-2:1-2:1-2, and at least one of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylamino hydroxybenzoyl hexyl benzoate is coated with a shell structure, said shell structure being prepared by mixing polymethylsilsesquioxane, lauroyl lysine, HDI / trimethylolhexyl lactone crosspolymer, polydimethylsiloxane, and triethoxyoctylsilane; Furthermore, the amount of each component added in the shell structure is as follows:

2. The sunscreen composition according to claim 1, characterized in that, The amount of each component added in the shell structure is as follows:

3. The sunscreen composition according to claim 1, characterized in that, The mass ratio of the shell structure to the bis-ethylhexyloxyphenol methoxyphenyl triazine and / or ethylhexyl triazine ketone and / or diethylamino hydroxybenzoyl hexyl benzoate encapsulated within the shell structure is 48–52:48–52.

4. A method for preparing a sunscreen composition, characterized in that, The method for preparing the sunscreen composition according to any one of claims 1-3 is as follows: a shell structure is prepared by mixing polymethylsilsesquioxane, lauroyl lysine, HDI / trimethylolhexyl lactone crosspolymer, polydimethylsiloxane, and triethoxyoctylsilane; the shell structure is then coated on the surface of at least one of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylaminohydroxybenzoyl hexyl benzoate; and the mixture of bis-ethylhexyloxyphenol methoxyphenyl triazine, ethylhexyl triazine ketone, and diethylaminohydroxybenzoyl hexyl benzoate is then used to prepare the sunscreen composition.

5. The use of the sunscreen composition as an active ingredient in any of claims 1-3.

6. A sunscreen daily chemical product, characterized in that, The sunscreen composition comprising any one of claims 1-3.

7. The sunscreen daily chemical product according to claim 6, characterized in that, The sunscreen products are in the form of creams, lotions, or sprays.

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