An embryo transfer device

By designing an embryo transfer device with an arc-shaped inner core and syringe assembly, precise aspiration and injection of embryos are achieved, solving the problem of traditional syringes being unable to accurately aspirate and damage the endometrium, thus improving the success rate and safety of transfer and reducing the risk of cross-infection.

CN117814887BActive Publication Date: 2026-02-17HENAN INST OF REPRODUCTIVE HEALTH SCI & TECH (HENAN BIRTH DEFECT INTERVENTION ENG TECH RES CENT)
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Patent Information

Application Number
CN202311758015.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-12-20
Publication Date
2026-02-17
Estimated Expiration
2043-12-20

AI Technical Summary

Technical Problem

The lack of a dedicated syringe for aspirating fluids during traditional embryo transfer processes leads to inaccurate embryo aspiration and can easily damage the endometrium, affecting the success rate and safety of the transfer.

Method used

An embryo transfer device comprising a cannula, an inner core, and a syringe has been designed. The inner core has an arc-shaped tail section. Together with the syringe and pressure cylinder, it achieves precise aspiration and injection of the embryo by controlling the air pressure, reducing damage to the endometrium. The design of disposable syringes and reusable pressure cylinders avoids cross-infection.

Benefits of technology

It improves the success rate and safety of embryo transfer, reduces endometrial damage and operational difficulty, lowers the risk of cross-infection, and improves surgical efficiency and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a medical instrument technical field, and relates to an embryo transfer device, which comprises a sleeve, an inner core and a syringe, the inner core is detachably connected with the syringe, the tail section of the inner core is provided with a circular arc structure at an opening, the thickness of the tube wall of the opening is gradually reduced from the opening to the tail section, and the inner wall of the tube wall of the opening is provided with a funnel structure; the syringe comprises a barrel, a pressurizing barrel is connected to the barrel, the inner diameter of the inner cavity of the barrel is smaller than the inner diameter of the inner cavity of the pressurizing barrel, a piston plate is arranged in the barrel, the piston plate is in sliding fit with the inner wall of the barrel, the pressurizing barrel is in communication with the barrel, a push plate is arranged in the pressurizing barrel, a push rod is connected to one side of the push plate, and the push rod penetrates through the pressurizing barrel. The special syringe is designed, the syringe and the inner core are used in cooperation, the embryo can be better controlled in suction and injection, the damage to the endometrium is reduced, the success rate and safety of embryo transfer are improved, and better treatment options are provided for infertile patients.
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Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical devices, and particularly relates to an embryo transfer device. BACKGROUND

[0002] Embryo transfer, also known as zygote transfer, is a technique of transferring an early embryo in a female animal or an embryo obtained through in vitro fertilization or other means into another female animal of the same species and in the same physiological condition to develop into a new individual.

[0003] In the traditional embryo transfer process, there is no special syringe for absorbing liquid, and most centers in the country use BD brand syringes, which are used for subcutaneous injection of patients in nursing and are not suitable for embryo transfer. Moreover, the port of the embryo transfer tube used at present for absorbing embryos is vertical with a flat cross section, which causes the front end to be thick and not easy to accurately absorb embryos. The vertical cross section also easily damages the endometrium. Therefore, the present application proposes an embryo transfer device to solve the above problems. SUMMARY

[0004] The present application proposes an embryo transfer device, which designs a special syringe, which can better control the absorption and injection of embryos by cooperating with the inner core, reduce the damage to the endometrium, and improve the success rate and safety of embryo transfer, thereby providing better treatment options for infertile patients.

[0005] In order to achieve the above purpose, the technical scheme of the present application is as follows: an embryo transfer device, comprising a sleeve, an inner core and a syringe, the inner core is detachably connected with the syringe, the tail section of the inner core is provided with a circular arc structure at the opening, and the thickness of the opening wall becomes thinner as it approaches the opening, the inner wall of the opening wall forms a funnel structure, and the other end of the inner core is connected with a connector.

[0006] The syringe comprises a barrel, the barrel is provided with a connecting port at one end, the connector is detachably connected with the connecting port, the outer wall of the barrel is fixedly connected with a pressurizing barrel, the inner diameter of the barrel is smaller than the inner diameter of the pressurizing barrel, a piston plate is installed inside the barrel, the piston plate is in sliding fit with the inner wall of the barrel, the pressurizing barrel is in communication with the barrel, the pressurizing barrel is provided with a push plate inside, the push plate is fixedly connected with a push rod at one side, and the push rod penetrates through the pressurizing barrel.

[0007] The above scheme has the following beneficial effects: when in use, the medical staff pushes the push rod, the push rod pushes the push plate, the push plate extrudes the air in the pressure cylinder, the air enters the syringe, the piston plate in the syringe is extruded downward, then the connecting port of the syringe is aligned with the protective liquid, then the push rod is released, the push plate and the push rod are lifted in the opposite direction, the piston plate in the syringe is reset, and the protective liquid is sucked into the syringe. Then connect the connector of the inner core with the connecting port of the syringe, repeat the above steps, inject the protective liquid in the syringe into the inner core, fill the inner core with the protective liquid, then align the inner core with the embryo, suck the embryo into the inner core, the medical staff inserts the cannula into the internal orifice of the uterine cervix, then inserts the inner core into the cannula and sends it into the uterine body, finally the medical staff can push the push rod again to push the embryo out of the inner core by the pressure of the air and inject it into the uterus. Through the cooperation of the syringe, the pressure cylinder and the inner core and other components, the embryo is accurately and safely transplanted into the uterus.

[0008] The pipe wall of the opening part of the tail section of the inner core of the embryo transfer device is in a circular arc structure, which can reduce the damage to the endometrium. Because of its shape, it can better adapt to the curve of the endometrium, making it easier to insert and remove, helping to reduce discomfort and pain during the operation, and reducing the risk of damage to the endometrium. The thickness of the pipe wall near the opening is thinner, and the inner side wall forms a funnel structure, which can better guide the insertion and removal of the inner core, making the operation process smoother, reducing the operation difficulty and time, and making the embryo suction and injection more accurate and reliable, thereby improving the success rate and safety of embryo transplantation.

[0009] Further, the outer side wall of the cylinder body is fixedly connected with a connecting assembly, the cylinder body is detachably connected with the pressure cylinder through the connecting assembly, the connecting assembly comprises a fixed outer shell and a fixed inner shell, the fixed outer shell is fixedly connected with the outer side wall of the cylinder body, and the fixed inner shell is fixedly connected with the outer side wall of the pressure cylinder. The fixed outer shell is in a "concave" structure, the inner side wall of the fixed outer shell is provided with a sliding groove, the bottom of the sliding groove on both sides is provided with a mounting port, the first spring is fixedly connected inside the mounting port, the end of the first spring away from the mounting port is fixedly connected with a limiting block, and the outer side wall of the fixed inner shell is provided with a sliding block matched with the sliding groove. The sliding block and the sliding groove are in sliding cooperation, and the sliding block on both sides is provided with a groove matched with the limiting block.

[0010] Beneficial effects: in order to avoid the cross infection risk caused by repeated use of the syringe, the syringe is a disposable product, and the pressure cylinder cleaned and disinfected can be reused, saving resources. When installing, the sliding block on the fixed inner shell of the pressure cylinder is aligned with the sliding groove on the fixed outer shell of the syringe, the sliding block is inserted into the sliding groove and slides to the bottom of the sliding groove. When the sliding block slides to the bottom, the limiting block on both sides of the sliding groove is extruded into the mounting port, and when the groove of the sliding block slides to the mounting port, the limiting block in the mounting port is clamped into the groove through the reset force of the first spring, so that the connection between the pressure cylinder and the syringe is more stable and firm.

[0011] Further, the length of the inner core is greater than the length of the sleeve, and the middle section of the inner core is composed of a metal material, and the tail section of the inner core is composed of a transparent soft material, and when the inner core is wrapped inside the sleeve, the middle section of the inner core is completely wrapped by the sleeve, and the tail section of the inner core extends out of the sleeve.

[0012] Beneficial effects: Since the inner core needs to be partially wrapped in the sleeve, considering the need to obtain embryos, inject embryos, and extend into the sleeve to facilitate injection into the human body, the inner core is provided with a middle section composed of a metal material and a tail section composed of a transparent soft material. When the inner core is wrapped inside the sleeve, the middle section of the inner core is completely wrapped by the sleeve, and the tail section extends out of the sleeve. The middle section is made of metal material to facilitate insertion into the sleeve, and the tail section is made of transparent soft material, considering that this part directly enters the human cervix when injecting embryos, so the material of the tail section should be selected to minimize damage to the internal microenvironment of the human body.

[0013] Further, the syringe and the pressure cylinder are made of transparent hard plastic, and the outer side walls of the syringe, the pressure cylinder and the push rod are provided with scale lines.

[0014] Beneficial effects: The transparent hard plastic and the scale lines can directly observe the amount of liquid in the syringe, which is convenient for medical staff to accurately control the injection amount. The scale lines on the outer side wall of the push rod can help medical staff accurately record the position of the push rod stroke, further ensuring the accuracy and safety of injection. The overall transparent design also facilitates medical staff to observe the state of the syringe and the pressure cylinder at any time during operation, and timely discover any problems and handle them. The choice of transparent material also facilitates cleaning and disinfection, improving the reusability of the equipment. This design improves the efficiency and safety of the operation by improving visibility and operational convenience.

[0015] Further, the pressure cylinder is fixedly connected with a wearing ring on both sides of the end penetrated by the push rod, and the push rod is fixedly connected with a handle at the end away from the push plate.

[0016] Beneficial effects: The design of the wearing ring can facilitate medical staff to fix the syringe on the finger, and the design of the handle can make medical staff better grasp the position and force of the push rod, so as to more accurately control the speed and amount of injection. These designs improve the efficiency and safety of the operation, reducing the fatigue of medical staff during operation.

[0017] Further, the push plate is fixedly connected with a second spring on one side, the second spring is sleeved on the push rod, and the other end of the second spring is fixedly connected with the inner wall of the pressure cylinder.

[0018] Beneficial effects: When medical staff push the plunger with the plunger, the second spring provides the force to reset the plunger, allowing it to automatically return to its original position after injection, preparing it for the next injection. Simultaneously, the spring's elasticity also cushions the force of the plunger push, preventing excessively rapid insertion and reducing the risk of injection errors due to human error, thus improving the ease of use and safety of the syringe.

[0019] Furthermore, both the piston plate and the push plate sidewalls are equipped with fluorescent markings and sealing rings.

[0020] Beneficial effects: The fluorescent markings on the side walls of the piston plate and push plate increase visibility and convenience during operation, allowing medical staff to accurately control the injection location and dosage during surgery, improving efficiency and safety. Simultaneously, the sealing ring design ensures the syringe's sealing performance, preventing drug leakage and air ingress, thus guaranteeing the safety and stability of the surgical procedure.

[0021] Furthermore, the total volume of the syringe cavity is 0.5 ml.

[0022] Beneficial effects: Because the total volume of the syringe lumen is fixed, the amount of embryos aspirated and injected each time is more precise, which can improve the success rate of embryo transfer by reducing the possibility of aspirating or injecting too much or too little. A fixed-volume syringe reduces the risks of over-injection, improving the safety and reliability of the procedure and reducing the risk of complications. Attached Figure Description

[0023] Figure 1 This is an isometric view of an embodiment of the embryo transfer device of the present invention.

[0024] Figure 2 This is a cross-sectional view of the inner core tail section in an embodiment of the embryo transfer device of the present invention.

[0025] Figure 3 This is a cross-sectional view of the syringe in an embodiment of the embryo transfer device of the present invention.

[0026] Figure 4 This is a cross-sectional view of the pressure cylinder in an embodiment of the embryo transfer device of the present invention.

[0027] Figure 5 This is a cross-sectional view of the fixed outer shell in an embodiment of the embryo transfer device of the present invention. Detailed Implementation

[0028] Embodiments of the present invention are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0029] In the description of this invention, it should be understood that the terms "longitudinal", "lateral", "vertical", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", and "outer" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0030] In the description of this invention, unless otherwise specified and limited, it should be noted that the terms "installation", "connection" and "linking" should be interpreted broadly. For example, they can refer to mechanical or electrical connections, or internal connections between two components. They can be direct connections or indirect connections through an intermediate medium. Those skilled in the art can understand the specific meaning of the above terms according to the specific circumstances.

[0031] The following detailed description illustrates the specific implementation method:

[0032] The reference numerals in the accompanying drawings include: inner core 1, syringe 2, barrel 201, connection port 202, piston plate 203, pressure cylinder 3, push plate 301, push rod 302, fixed outer shell 4, slide groove 401, mounting port 402, first spring 403, limit block 404, second spring 5, and handle 6.

[0033] Example 1, basically as shown in the attached document. Figures 1-4 The image shows an embryo transfer device comprising a cannula, an inner core 1, and a syringe 2. The inner core 1 is detachably connected to the syringe 2. The inner core 1 has an arc-shaped wall at its tail end, with the wall thickness decreasing towards the opening. The inner wall at the opening forms a funnel structure. A connector is connected to the other end of the inner core 1. The length of the inner core 1 is greater than the length of the cannula. The middle section of the inner core 1 is made of metal, while the tail end is made of a transparent, soft material. When the inner core 1 is enclosed within the cannula, the middle section is completely enclosed, while the tail end protrudes beyond the cannula.

[0034] The syringe 2 includes a barrel 201 with a connection port 202 at one end. A connector is detachably connected to the connection port 202. A pressure cylinder 3 is fixedly connected to the outer wall of the barrel 201. The inner diameter of the barrel 201 is smaller than the inner diameter of the pressure cylinder 3. A piston plate 203 is installed inside the barrel 201, and the piston plate 203 slides against the inner wall of the barrel 201. The pressure cylinder 3 communicates with the barrel 201. A push plate 301 is provided inside the pressure cylinder 3, and a push rod 302 is fixedly connected to one side of the push plate 301, penetrating the pressure cylinder 3. Both the piston plate 203 and the push plate 301 have fluorescent markings and sealing rings on their side walls. The total volume of the syringe 2 is 0.5 ml. A second spring 5 is fixedly connected to one side of the push plate 301, and the second spring 5 is sleeved on the push rod 302. The other end of the second spring 5 is fixedly connected to the inner wall of the pressure cylinder 3.

[0035] Both the syringe 2 and the pressure cylinder 3 are made of transparent hard plastic, and scale lines are provided on the outer walls of the syringe 2, the pressure cylinder 3 and the push rod 302.

[0036] The pressure cylinder 3 is penetrated by the push rod 302, and both sides are fixedly connected to the wear rings. The end of the push rod 302 away from the push plate 301 is fixedly connected to the handle 6.

[0037] The specific implementation process is as follows: When in use, medical staff put their fingers through the wearing ring and push the push rod 302 through the handle 6. The push rod 302 pushes the push plate 301, and the push plate 301 squeezes the air in the pressure cylinder 3. The air enters the syringe 2 and squeezes the piston plate 203 in the syringe 2 downward. Then, the connection port 202 of the syringe 2 is aligned with the protective fluid. Then, the push rod 302 is released, and the push plate 301 and the push rod 302 are lifted in opposite directions by the restoring force of the second spring 5. The piston plate 203 in the syringe 2 is then reset, thereby drawing the protective fluid into the syringe 2.

[0038] Then connect the connector of the inner core 1 to the connector 202 of the syringe 2, repeat the above steps, inject the protective fluid in the syringe 2 into the inner core 1 to fill the inner core 1, then align the inner core 1 with the embryo, and draw the embryo into the inner core 1. The medical staff inserts the cannula into the internal os of the cervix, then inserts the inner core 1 into the cannula and sends it into the uterine body. Finally, the medical staff can push the push rod 302 again to use air pressure to push the embryo out of the inner core 1 and inject it into the uterus.

[0039] The inner core 1 of this embryo transfer device features a rounded wall at its opening, reducing damage to the endometrium. Its shape better conforms to the curve of the endometrium, making insertion and removal easier and minimizing discomfort and pain during the procedure, while also reducing the risk of endometrial damage. During insertion, the syringe 2's total volume of 0.5ml prevents excessive absorption of protective fluid. Compared to traditional syringes 2, the smaller total volume also reduces the inner diameter, increasing the length of the fluid segment during aspiration. This allows for more precise observation of the aspirated fluid volume and more accurate control over the aspiration and injection amount. The second spring 5 increases the resistance of the push rod 302, allowing for slower embryo injection and better speed control, ensuring the embryo enters the uterine cavity slowly and settles at the intended position. Simultaneously, the doctor can clearly and visually observe the advancement of the syringe 2's piston plate 203, estimating when the embryo-carrying fluid segment will enter the uterine cavity. This allows for better monitoring of the procedure and more informed decision-making regarding the next step.

[0040] Example 2 differs from the above examples in that, as shown in the appendix... Figure 5 As shown: A connecting assembly is fixedly connected to the outer wall of the cylinder 201. The cylinder 201 is detachably connected to the pressure cylinder 3 through the connecting assembly. The connecting assembly includes a fixed outer shell 4 and a fixed inner shell. The fixed outer shell 4 is fixedly connected to the outer wall of the cylinder 201, and the fixed inner shell is fixedly connected to the outer wall of the pressure cylinder 3. The fixed outer shell 4 has a concave structure. The inner wall of the fixed outer shell 4 is provided with a sliding groove 401. The bottom of both sides of the sliding groove 401 is provided with an installation port 402. A first spring 403 is fixedly connected inside the installation port 402. A limit block 404 is fixedly connected to the end of the first spring 403 away from the installation port 402. The outer wall of the fixed inner shell is provided with a slider that matches the sliding groove 401. The slider slides in cooperation with the sliding groove 401. The slider is provided with a groove on both sides that matches the limit block 404.

[0041] The specific implementation process is as follows: To avoid the risk of cross-infection from reusing syringe 2, syringe 2 is a disposable item, while the pressure cylinder 3, after cleaning and disinfection, can be reused, saving resources. During installation, align the slider on the inner shell of the pressure cylinder 3 with the groove 401 on the outer shell 4 of the syringe 2, and insert the slider into the groove 401 and slide it towards the bottom of the groove 401. When the slider reaches the bottom, it pushes the limiting blocks 404 on both sides of the groove 401 into the mounting port 402. When the groove of the slider slides to the mounting port 402, the limiting blocks 404 in the mounting port 402 are locked into the groove by the restoring force of the first spring 403, making the connection between the pressure cylinder 3 and the syringe 2 more stable and secure.

[0042] The above descriptions are merely embodiments of the present invention, and common knowledge such as specific structures and / or characteristics in the solutions are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the structure of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. An embryo transfer device, characterized in that: It includes a cannula, an inner core, and a syringe. The inner core and the syringe are detachably connected. The tube wall at the opening of the tail section of the inner core has an arc-shaped structure, and the tube wall thickness at the opening is thinner as it approaches the opening. The inner wall of the tube wall at the opening forms a funnel structure. The other end of the inner core is connected to a connector. The syringe includes a barrel, one end of which has a connection port. A connector is detachably connected to the connection port. A pressure cylinder is fixedly connected to the outer wall of the barrel. The inner diameter of the barrel is smaller than the inner diameter of the pressure cylinder. A piston plate is installed inside the barrel. The piston plate slides against the inner wall of the barrel. The pressure cylinder communicates with the barrel. A push plate is provided inside the pressure cylinder. A push rod is fixedly connected to one side of the push plate. The push rod passes through the pressure cylinder. A connecting assembly is fixedly connected to the outer wall of the cylinder. The cylinder is detachably connected to the pressure cylinder through the connecting assembly. The connecting assembly includes a fixed outer shell and a fixed inner shell. The fixed outer shell is fixedly connected to the outer wall of the cylinder, and the fixed inner shell is fixedly connected to the outer wall of the pressure cylinder. The fixed outer shell has a "concave" structure. The inner wall of the fixed outer shell is provided with a sliding groove. There is an installation port at the bottom of both sides of the sliding groove. A first spring is fixedly connected inside the installation port. A limit block is fixedly connected to the end of the first spring away from the installation port. The outer wall of the fixed inner shell is provided with a slider that matches the sliding groove. The slider slides in cooperation with the sliding groove. There are grooves on both sides of the slider that match the limit block.

2. The embryo transfer device according to claim 1, characterized in that: The inner core is longer than the sleeve. The middle section of the inner core is made of metal, while the tail section is made of transparent soft material. When the inner core is wrapped inside the sleeve, the middle section of the inner core is completely wrapped by the sleeve, and the tail section of the inner core extends out of the sleeve.

3. The embryo transfer device according to claim 1, characterized in that: Both the syringe and the pressure cylinder are made of transparent rigid plastic, and the outer walls of the syringe, pressure cylinder, and plunger are equipped with scale lines.

4. The embryo transfer device according to claim 1, characterized in that: The pressure cylinder is penetrated by a push rod, and both sides are fixedly connected to wearing rings. A handle is fixedly connected to the end of the push rod away from the push plate.

5. The embryo transfer device according to claim 1, characterized in that: A second spring is fixedly connected to one side of the push plate. The second spring is sleeved on the push rod, and the other end of the second spring is fixedly connected to the inner wall of the pressure cylinder.

6. The embryo transfer device according to claim 1, characterized in that: Both the piston plate and the push plate sidewalls are equipped with fluorescent markings and sealing rings.

7. The embryo transfer device according to claim 1, characterized in that: The total volume of the syringe's inner cavity is 0.5 ml.

Citation Information

Patent Citations

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  • Anesthesia device for obstetrics and gynecology department

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