Inhalable dry powder formulation nebulizer device

Abstract

The application discloses an inhalable dry powder preparation atomization equipment and belongs to the technical field of medical equipment. The inhalable dry powder preparation atomization equipment comprises an atomization equipment rack, a placing bin is formed in one side of the atomization equipment rack, a medicine supplying mechanism and a separating mechanism are arranged in the placing bin, the separating mechanism comprises a separating box, and the medicine supplying mechanism comprises a medicine cabin which is arranged in the placing bin, a plurality of hemispherical medicine grooves are formed in the medicine cabin, a medicine outlet is formed in the bottom of the separating box, a rack is arranged at the bottom of the medicine cabin, a first gear is engaged with the bottom of the rack, a concave frame is arranged at the bottom of the medicine cabin, a driving motor is arranged at the lower side of the concave frame, sliding blocks are arranged at the two sides of the rack, the sliding blocks are connected with the ends of rotating rods through crank rocker assemblies, and jacks are connected with the top of the sliding blocks. The first gear, the second gear, the rack, the crank slider and various mechanical mechanisms are organically combined, so that orderly and accurate supply of multiple doses of dry powder preparation can be realized.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to an inhalable dry powder atomization device. Background Technology

[0002] In the treatment of respiratory diseases such as chronic obstructive pulmonary disease, asthma, and local lung infections, dry powder inhalers (DPIs) have advantages over liquid-based nebulizers and metered-dose inhalers, including high drug delivery capacity, high drug stability, and low biofouling, thus making them highly competitive in the market.

[0003] The drug particles (1-5 micrometers, also known as Active Pharmaceutical Ingredients, API particles) used in dry powder inhalers typically adhere to the surface of larger carrier particles (40-500 micrometers, mostly made of lactose), forming a particle aggregate. By modifying the surface of the carrier particles, the adhesion between the drug particles and the carrier particles can be effectively reduced. Its working principle utilizes the design of the inhaler's internal flow area, which, under the combined effects of fluid stress and wall collisions, causes the drug particles to separate from the carrier particle surface within the inhaler, thus allowing them to enter the respiratory tract and achieve a therapeutic effect.

[0004] CN113750331A discloses a dry powder inhaler, which features a particle rotation and collision chamber structure with different inclined walls. This significantly increases the number of collisions between the carrier particles and the walls, thereby effectively improving the separation efficiency of drug particles from the carrier particles. Furthermore, it employs a blister pack, avoiding the need for inserting, puncturing, and removing capsules as required by traditional dry powder inhalers, thus enhancing the user experience. However, patients typically need to fill all the medication compartments at once before use. Using a single-dose compartment would greatly reduce the user experience. In this case, precise control of the delivery time interval for each dose of dry powder formulation is required. Additionally, a gap exists between the blister pack structure and the particle rotation and collision chamber. When an external power drive is used to inject airflow into the dry powder inhaler, this gap widens further, significantly reducing the device's sealing performance. Summary of the Invention

[0005] The purpose of this invention is to overcome the problems in the prior art. It adopts a combination of a first gear, a second gear, a rack, a crank slider, and a variety of mechanical mechanisms to achieve orderly and precise supply of multi-dose dry powder preparations, and provides an inhalable dry powder preparation atomization device.

[0006] This invention provides an inhalable dry powder atomizing device, including a separation chamber and a drug supply mechanism. The drug supply mechanism is located below the separation chamber and includes a drug chamber placed inside a placement compartment. The drug chamber has several hemispherical drug slots arranged in a single row along its length. A drug outlet is located at the bottom of the separation chamber, with the outlet having the same radius as the hemispherical drug slots. A gap exists between the top of the drug chamber and the bottom of the separation chamber. A horizontally moving part is located on the lower side of the drug chamber, including a rack fixedly connected to the bottom of the drug chamber. The rack is aligned with the hemispherical drug slot array direction. A wheel meshes with the bottom of the rack. A concave frame is provided at the bottom of the medicine compartment. The first gear is rotatably mounted on the concave frame via a rotating rod. Both ends of the rotating rod pass through the concave frame. The first gear is provided with a driving component. A vertical lifting part is provided on the lower side of the medicine compartment. The vertical lifting part includes a slider. A sliding groove is opened in the slider. The slider is provided on both sides of the rack. The slider is connected to the shaft end of the rotating rod through a crank-rocker assembly. A mounting bracket is fixedly connected to the bottom of the concave frame. The slider is slidably embedded in the mounting bracket. A top rod is slidably arranged in the sliding groove. The top of the top rod abuts against the bottom of the medicine compartment at its farthest stroke.

[0007] This invention relates to a gear and rack structure for the orderly and precise supply of dry powder formulations within a multi-dose medication chamber. The upper part of the medication chamber consists of equidistantly arranged hemispherical medication reservoirs, while the lower part is a rack structure. To ensure the proper functioning of the second gear and rack structure, a gap exists between the top of the medication chamber and the bottom of the rotating chamber (e.g., ...). Figure 2 (As shown). During the execution of the dry powder formulation supply action, the upward movement of the drug chamber is completed by a mechanical mechanism, which effectively seals the drug supply structure and ensures that a large amount of dry powder formulation can enter the separation mechanism to complete depolymerization. Based on this requirement, this invention introduces a crank-slider mechanism and a push rod mechanism. During the first half-turn of the drive shaft rotation, since the crank is coaxial with the first gear, the connecting rod will push the slider to move during the gear and rack meshing process; and since the push rod can only move up and down and is located in the groove of the slider, the push rod will make the top of the drug chamber fit tightly against the bottom of the rotating chamber when the supply action is completed (at this time, the gear and rack are no longer meshing). During the second half-turn of the drive shaft rotation, the push rod will gradually move down, and the drug chamber will continue to descend under the action of gravity until the rack and gear at its bottom re-mesh. In summary, the two actions of drug supply and upward movement (ensuring sealing) can be achieved simultaneously by a single rotation of the drive shaft.

[0008] Preferably, the crank-rocker assembly includes a crank and a connecting rod, one end of the connecting rod is fixedly sleeved on the rotating rod, the crank is hinged to the connecting rod, and the connecting rod is hinged to the slider.

[0009] Preferably, the chute is composed of a first channel and a second channel arranged horizontally, the first channel and the second channel being opened along the length direction of the rack, the first channel and the second channel having a height difference in the vertical direction, the vertical height of the chute depending on the gap between the top of the medicine compartment and the separation box, and the first channel and the second channel being connected by an inclined third channel.

[0010] Preferably, the separation mechanism further includes a rotating chamber, a first airflow pipe, a grid, and a diversion chamber. The rotating chamber is placed inside the separation box and is located at the top of the drug outlet. The rotating chamber and the diversion chamber are connected through the first airflow pipe. A conveying pipe is connected to the top of the rotating chamber, and a grid is provided at the position where the conveying pipe communicates with the rotating chamber.

[0011] Preferably, the separation mechanism further includes a second airflow pipe, a buffer chamber, and a third airflow pipe. One side of the buffer chamber is connected to a pair of the diversion chambers via the second airflow pipe, and the other side of the buffer chamber is connected to the third airflow pipe.

[0012] High-pressure airflow enters through the third airflow pipe, passes through the buffer chamber, the diversion chamber, and the first airflow pipe in sequence, and then enters the rotating chamber. It blows up the dry powder preparation in the drug compartment located directly below the rotating chamber. The dry powder preparation rises to the rotating chamber under the action of the airflow and collides with its wall continuously. The drug particles will separate from the surface of the carrier particles due to inertia. The separated drug particles pass through the grid under the action of the flow field and finally enter the human airway through the delivery pipe.

[0013] Preferably, the flow dividers are configured as a pair, with the pair of flow dividers respectively located on both sides of the rotating chamber. The inlet cross-section of the first airflow pipe is parallelogram-shaped, and the first airflow pipes used for communication are respectively connected to the farthest sides of the rotating chamber and are tangent to the rotating chamber.

[0014] Because the rotating chamber has inclined walls, and the airflow inlet needs to be tangent to these walls, the cross-section of the airflow inlet is a quadrilateral with a corresponding inclination angle. During operation, the flow rates at the two rotating chamber inlets must be similar to ensure a symmetrical and stable flow field within the rotating chamber, thereby improving drug particle separation. Therefore, two symmetrically arranged split chambers are introduced. Considering that the power source is typically a single-outlet structure, a buffer chamber connected to the split chambers at both ends by circular pipes is added.

[0015] Preferably, the rotating chamber and the separation box are connected by a plug-in structure, the mesh is detachably plugged into the drug outlet of the rotating chamber, and the delivery pipe is detachably plugged into the drug outlet of the rotating chamber.

[0016] Preferably, the driving component includes a drive motor, which is mounted on the frame of the atomizing device. A second gear is fixedly connected to the output end of the drive motor, and the second gear meshes with the bottom of the first gear.

[0017] Compared with the prior art, the beneficial effects of the present invention are:

[0018] 1. The drug supply mechanism of the present invention adopts a combination of multiple mechanical mechanisms such as gear rack, crank slider, and push rod, which can realize the orderly and precise supply of multi-dose dry powder preparations. In addition, during the atomization process, it can fully ensure the sealing between the upper end of the drug chamber and the bottom end of the separation mechanism, so that a large amount of dry powder preparations can enter the separation mechanism to complete the depolymerization.

[0019] 2. The internal flow structure of the separation mechanism of the present invention introduces a diversion chamber and a buffer chamber. For a single-outlet power source, it can achieve similar flow rates at the air inlets of the two rotating chambers, thereby ensuring a symmetrical and stable flow field is generated in the rotating chamber, which is beneficial to improving the separation of drug particles.

[0020] 3. The airflow delivery mechanism of the present invention can provide a continuous and sufficiently large flow of air to fully separate drug particles, and ensures that the gas inhaled by the patient is clean and sterile through a bacterial filter, thus making it suitable for critically ill patients. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the overall structure of the present invention;

[0022] Figure 2 This is a schematic diagram of the drug supply mechanism of the present invention;

[0023] Figure 3 This is a schematic diagram of the slider structure of the present invention;

[0024] Figure 4 This is a schematic diagram of the layout of the slider push rod of the present invention;

[0025] Figure 5 This is a schematic diagram of the internal flow structure of the separation mechanism of the present invention.

[0026] Figure 6 This is a pneumatic circuit diagram of the airflow conveying mechanism of the present invention;

[0027] Explanation of reference numerals in the attached drawings: 1. Nebulizer frame; 2. Storage chamber; 3. Drug supply mechanism; 31. Drug compartment; 32. Hemispherical drug reservoir; 33. Drug outlet; 34. Rack; 35. Concave frame; 36. Rotating rod; 37. Drive motor; 38. First gear; 39. Second gear; 310. Slider; 311. Push rod; 4. Crank-rocker assembly; 41. Crank; 42. Connecting rod; 5. Slide groove; 51. First channel; 52. Second channel; 53. Third channel connection; 6. Separation mechanism; 61. Separation box; 62. Rotating chamber; 63. First airflow pipe; 64. Grid; 65. Diversion chamber; 66. Delivery pipe; 67. Second airflow pipe; 68. Buffer chamber; 69. Third airflow pipe; 7. Mounting bracket; 8. Airflow delivery mechanism; 81. Bacterial filter; 82. Turbine fan; 83. Pressure reducing valve; 84. Check valve; 85. Pressure sensor; 86. Flow sensor; 87. Safety valve; 88. Gas solenoid directional valve; 89. Ventilator. Detailed Implementation

[0028] The following is in conjunction with the appendix Figure 1-6 To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the described embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. Unless otherwise defined, the technical or scientific terms used herein should have the ordinary meaning understood by those skilled in the art.

[0029] The terms "first," "second," and similar words used in the specification and claims of this patent application do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed after the word and their equivalents, without excluding other elements or objects. Terms such as "inner," "outer," "upper," "lower," "far," "near," "front," and "back" are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly. The drawings in this disclosure are not strictly drawn to scale; the specific dimensions and quantity of each structure can be determined according to actual needs. The drawings described in this disclosure are merely structural schematic diagrams.

[0030] This invention provides an inhalable dry powder formulation atomization device, such as... Figure 1-4As shown, the system includes a separation box 61 and a drug supply mechanism 3, which is located below the separation box. The drug supply mechanism 3 includes a drug chamber 31, which is placed inside a storage compartment 2. The drug chamber 31 has several hemispherical drug troughs 32, which are arranged in a single row along the length of the drug chamber 31. The bottom of the separation box 61 has a drug outlet 33, which has the same radius as the hemispherical drug troughs 32. There is a gap between the top of the drug chamber 31 and the bottom of the separation box 61. A water tank is provided on the lower side of the drug chamber 31. The horizontally moving part includes a rack 34, which is fixedly connected to the bottom of the medicine chamber 31. The rack 34 is aligned with the hemispherical medicine trough 32. A first gear 38 meshes with the bottom of the rack 34. A concave frame is provided at the bottom of the medicine chamber 31. The first gear 38 is rotatably mounted on the concave frame 35 via a rotating rod 36. Both ends of the rotating rod 36 pass through the concave frame 35. The first gear 38 is equipped with a driving component. A vertical lifting part is provided on the lower side of the medicine chamber 31. The vertical lifting part includes a slider 310. A groove 5 is provided inside the rack 34. A slider 310 is disposed on both sides of the rack 34. The slider 310 is connected to the shaft end of the rotating rod 36 through a crank-rocker assembly 4. A mounting bracket 7 is fixedly connected to the bottom of the concave frame 35. The slider 310 is slidably embedded in the mounting bracket 7. A top rod 311 is slidably disposed inside the groove 5. The top of the top rod 311 abuts against the bottom of the medicine compartment 31 at its farthest stroke. The groove 5 is composed of a first channel 51 and a second channel 52 arranged horizontally. The first channel 51 and the second channel 52 are along the rack 34. 4. The first channel 51 and the second channel 52 are opened in the length direction. There is a height difference in the vertical direction. The vertical height of the slide 5 depends on the gap between the top of the medicine chamber 31 and the rotating chamber 62. The first channel 51 and the second channel 52 are connected by an inclined third channel 53. The driving component includes a drive motor 37. The drive motor 37 is mounted on the frame 1 of the atomizing device. The output end of the drive motor 37 is fixedly connected to a second gear 39. The second gear 39 meshes with the bottom of the first gear 38.

[0031] The drug supply mechanism 3 of the present invention adopts a combination of multiple mechanical mechanisms such as gear rack, crank slider, and cam push rod, which can realize the orderly and precise supply of multi-dose dry powder preparations. In addition, during the atomization process, it can fully ensure the sealing between the upper end of the drug chamber and the bottom end of the separation mechanism 6, so that a large amount of dry powder preparations can enter the separation mechanism 6 to complete the depolymerization.

[0032] To achieve orderly and precise supply of dry powder formulations in a multi-dose drug chamber, a gear and rack structure is adopted. The upper part of the drug chamber consists of equidistantly arranged hemispherical drug slots 32, and the lower part is a rack structure; and to ensure the normal operation of the gear and rack structure, there is a gap between the top of the drug chamber and the bottom of the rotating chamber 62. During the execution of the dry powder formulation supply action, the upward movement of the drug chamber is completed by a mechanical mechanism, which can effectively achieve the sealing of the drug supply structure and ensure that a large amount of dry powder formulation can enter the separation mechanism 6 to complete depolymerization. Based on this requirement, the present invention introduces a crank-slider mechanism and a push rod mechanism. During the first half-turn rotation of the drive shaft, since the crank 41 is coaxial with the first gear 38, the connecting rod 42 will push the slider 310 to move during the meshing of the first gear 38 and rack 34; and since the push rod 311 can only move up and down and is located in the groove of the slider 310, when the supply action is completed, the push rod 311 will make the top of the drug chamber 31 tightly fit with the bottom of the rotating chamber 62 (at this time, the gear and rack are no longer meshed). During the second half of the drive shaft's rotation, the push rod 311 gradually moves downwards, continuing to descend under the influence of gravity until its bottom rack 34 re-engages with the first gear 38. In summary, the two actions of drug delivery and upward lifting (ensuring sealing) can be achieved simultaneously through a single rotation of the drive shaft.

[0033] Preferred, such as Figure 5-6 As shown, the separation mechanism 6 also includes a rotating chamber 62, a first airflow pipe 63, a mesh 64, and a diversion chamber 65. The rotating chamber 62 is placed inside the separation box 61 and is fastened to the top of the drug outlet 33. The rotating chamber 62 and the diversion chamber 65 are connected by the first airflow pipe 63. A conveying pipe 66 is connected to the top of the rotating chamber 62. A mesh 64 is provided at the position where the conveying pipe 66 connects to the rotating chamber 62. The diversion chambers 65 are configured as a pair, with the pair of diversion chambers 65 respectively located on both sides of the rotating chamber 62. The separation mechanism 6 also includes a second airflow pipe 67 and a buffer chamber. The buffer chamber 68 and the third airflow pipe 69 are connected on one side to a pair of diversion chambers 65 via the second airflow pipe 67. The inlet cross section of the first airflow pipe 63 is parallelogram-shaped, and the first airflow pipe 63 used for connection is connected to the farthest two sides of the rotating chamber 62, and the other side of the buffer chamber 68 is connected to the third airflow pipe 69, which is tangent to the rotating chamber 62. The rotating chamber 62 and the separation box 61 are spliced ​​with a plug-in structure. The grid 64 is detachably inserted into the drug outlet of the rotating chamber 62, and the delivery pipe 66 is detachably inserted into the drug outlet of the rotating chamber 62.

[0034] Because the rotating chamber 62 has an inclined cross-section, and the airflow inlet of the rotating chamber 62 needs to be tangent to it, the cross-section of the airflow inlet of the rotating chamber 62 is a quadrilateral with a corresponding inclination angle. During the operation of the device, the flow rates of the two airflow inlets of the rotating chamber 62 must be similar to ensure that a symmetrical and stable flow field is generated within the rotating chamber 62, thereby improving the separation of drug particles. Therefore, two symmetrically arranged diversion chambers 65 are introduced. Considering that the power source is usually a single-outlet structure, a buffer chamber 68 is added, with both ends connected to the diversion chamber 65 by circular pipes. The internal flow structure of the separation mechanism 6 of the present invention incorporates the diversion chamber 65 and the buffer chamber 68. For a single-outlet power source, it is possible to achieve similar flow rates at the two airflow inlets of the rotating chamber 62, thereby ensuring a symmetrical and stable flow field within the rotating chamber 62, which is beneficial to improving the separation of drug particles.

[0035] Preferred, such as Figure 5-6 As shown, the airflow delivery mechanism 8 includes a turbine fan 82, a one-way valve 84, a pressure sensor 85, a flow sensor 86, a safety valve 87, a gas solenoid reversing valve 88, and circuit control components to achieve continuous airflow delivery for different durations of 0.5 s to 60 s and different flow ranges of 5 L / min to 400 L / min, and adds a bacterial filter 81.

[0036] The flow delivery mechanism provides high-pressure airflow to the separation mechanism 6. The high-pressure airflow enters from the third airflow pipe 69, passes through the buffer chamber 68, the diversion chamber 65, and the first airflow pipe 63 in sequence, and then enters the rotating chamber 62. It blows up the dry powder preparation in the drug compartment located directly below the rotating chamber 62. The dry powder preparation rises to the rotating chamber 62 under the action of the airflow and collides with its wall continuously. The drug particles will separate from the surface of the carrier particles due to inertia. The separated drug particles pass through the grid 64 under the action of the flow field and finally enter the human airway through the outlet.

[0037] The method of using the inhalable dry powder formulation atomization device of the present invention is as follows:

[0038] The drive motor 37 drives the second gear 39 to rotate, which in turn causes the first gear 38 to mesh with the rack 34 at the bottom of the medicine chamber 31, ultimately achieving precise engagement between the hemispherical medicine tank 32 and the medicine outlet 33 of the separation mechanism 6. Since one end of the crank 41 is connected to the rotating rod 36, the crank 41, which is in a circular motion, will drive the connecting rod 42 to move during the process of the rack 34 driving the medicine chamber 31. Finally, the connecting rod 42 will push the slider 310 to move horizontally in a straight line. When the slider 310 reaches its closest stroke, the push rod 311 located in its groove moves upward to complete the upward action and ensure the sealing of the device. During the return stroke of the slider 310, the push rod 311 will gradually move downward, and the medicine chamber 31 will continue to descend under the action of gravity until the rack 34 at its bottom re-meshes with the first gear 38.

[0039] First, switch the gas solenoid reversing valve 88 to the left position and turn on the turbine fan 82. Air, after being processed by the bacterial filter 81, directly enters the turbine fan 82. Adjust the safety valve 87 and observe the readings of the pressure sensor 85 and the flow sensor 86. When the flow sensor 86 reaches the predetermined working flow rate and the pressure stabilizes, switch the gas solenoid reversing valve 88 to the right position. Finally, the pressurized airflow is directly injected into the third airflow pipe 69 of the separation mechanism 6 at a certain flow rate. Since the output airflow duration and flow rate of the airflow delivery mechanism 8 will directly affect the atomization effect of the dry powder preparation in the separation mechanism 6, it is designed to achieve continuous airflow delivery with different durations of 0.5 s to 60 s and different flow rates of 5 L / min to 400 L / min. In addition, the power source can also be replaced with compressed oxygen, which can be directly connected to the pneumatic circuit via the pressure reducing valve 83.

[0040] The high-pressure airflow injected into the third airflow pipe 69 of the separation mechanism 6 passes sequentially through the buffer chamber 68, the diversion chamber 65, and the first airflow pipe 63 before entering the rotating chamber 62. This airflow blows up the dry powder preparation located in the drug compartment directly below the rotating chamber 62. Under the influence of the airflow, the dry powder preparation rises to the rotating chamber 62 and continuously collides with its walls. Due to inertia, the drug particles separate from the carrier particle surface. The separated drug particles then pass through the grid 64 under the influence of the flow field and finally enter the aerosol chamber via the delivery pipe 66. For critically ill patients, it is difficult to actively inhale the atomized drug particles from the aerosol chamber into the respiratory tract; therefore, a ventilator 89 is required for assisted inhalation therapy.

[0041] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An inhalable dry powder atomizing device, comprising a separation chamber (61), characterized in that, It also includes a drug supply mechanism (3), which is located below the separation box (61), and the drug supply mechanism (3) includes: A medicine compartment (31) is placed inside a storage compartment (2). The medicine compartment (31) has several hemispherical medicine slots (32) arranged in a single row along the length of the medicine compartment (31). The separation box (61) has a medicine outlet hole (33) at the bottom. The medicine outlet hole (33) has the same radius as the hemispherical medicine slots (32). There is a gap between the top of the medicine compartment (31) and the bottom of the separation box (61). A horizontal moving part is disposed on the lower side of the medicine chamber (31). The horizontal moving part includes a rack (34) fixedly connected to the bottom of the medicine chamber (31). The rack (34) is in the same direction as the array of the hemispherical medicine grooves (32). A first gear (38) meshes with the bottom of the rack (34). A concave frame (35) is disposed at the bottom of the medicine chamber (31). The first gear (38) is rotatably mounted on the concave frame (35) through a rotating rod (36). Both ends of the rotating rod (36) pass through the concave frame (35). The first gear (38) is provided with a driving member. A vertical lifting part is provided on the lower side of the medicine compartment (31), including a slider (310), a groove (5) is provided in the slider (310), the slider (310) is provided on both sides of the rack (34), the slider (310) is connected to the shaft end of the rotating rod (36) through a crank rocker assembly (4), a mounting bracket (7) is fixedly connected to the bottom of the concave frame (35), and the slider (310) is slidably embedded in the mounting bracket (7); a top rod (311) is placed in the groove (5), and the top of the top rod (311) abuts against the bottom of the medicine compartment (31) when the travel is at its farthest point; The crank rocker assembly (4) includes a crank (41) and a connecting rod (42). One end of the connecting rod (42) is fixedly sleeved on the rotating rod (36). The crank (41) is hinged to the connecting rod (42), and the connecting rod (42) is hinged to the slider (310). The chute (5) is composed of a first channel (51) and a second channel (52) arranged horizontally. The first channel (51) and the second channel (52) are opened along the length direction of the rack (34). The first channel (51) and the second channel (52) have a height difference in the vertical direction. The vertical height of the chute (5) depends on the gap between the top of the medicine compartment (31) and the separation box (61). The first channel (51) and the second channel (52) are connected by an inclined third channel (53).

2. The inhalable dry powder preparation atomizing device as described in claim 1, characterized in that, The separation mechanism (6) also includes a rotating chamber (62), a first airflow pipe (63), a grid (64), and a diversion chamber (65). The rotating chamber (62) is placed inside the separation box (61). The rotating chamber (62) is fastened to the top of the drug outlet (33). The rotating chamber (62) and the diversion chamber (65) are connected through the first airflow pipe (63). A conveying pipe (66) is connected to the top of the rotating chamber (62). A grid (64) is provided at the position where the conveying pipe (66) communicates with the rotating chamber (62).

3. The inhalable dry powder atomizing device as described in claim 2, characterized in that, The separation mechanism (6) further includes a second airflow pipe (67), a buffer chamber (68) and a third airflow pipe (69). One side of the buffer chamber (68) is connected to a pair of the diversion chambers (65) through the second airflow pipe (67), and the other side of the buffer chamber (68) is connected to the third airflow pipe (69).

4. The inhalable dry powder preparation atomizing device as described in claim 2, characterized in that, The flow divider (65) is configured as a pair, and the pair of flow divider (65) are respectively placed on both sides of the rotating chamber (62). The inlet cross section of the first airflow pipe (63) is a parallelogram shape, and the first airflow pipe (63) used for communication is respectively connected to the farthest two sides of the rotating chamber (62) and is tangent to the rotating chamber (62).

5. The inhalable dry powder atomizing device as described in claim 2, characterized in that, The rotating chamber (62) and the separation box (61) are connected by a plug-in structure. The grid (64) is detachably plugged into the drug outlet of the rotating chamber (62), and the delivery pipe (66) is detachably plugged into the drug outlet of the rotating chamber (62).

6. The inhalable dry powder preparation atomizing device as described in claim 1, wherein the driving component includes a drive motor (37), the drive motor (37) is mounted on the frame (1) of the atomizing device, and a second gear (39) is fixedly connected to the output end of the drive motor (37), the second gear (39) meshing with the bottom of the first gear (38).

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