A balloon catheter capable of rapidly releasing drugs

Abstract

The invention relates to the technical field of balloon catheters, and more specifically to a balloon catheter capable of rapidly releasing drugs, comprising a rapid drug delivery component and a transit positioning component, wherein the rapid drug delivery component comprises a drug delivery balloon body, both ends of the drug delivery balloon body are covered with gas matching components, the inner sides of the two gas matching components are jointly interspersed with a catheter, the catheter is interspersed with the drug delivery balloon body, an inner lining component is arranged inside the drug delivery balloon body, and the transit positioning component comprises an auxiliary gas disk, the inner wall of the auxiliary gas disk is fixedly connected with a guide sleeve, and a guide port is opened on the upper part of the guide sleeve, and an isolation sheet engaged with the guide sleeve is transversely arranged inside the auxiliary gas disk, which is beneficial to preventing the loss of the drug carried by the balloon during the intervention of the blood vessel, and can avoid the balloon from sliding during drug delivery, and reduce the accumulation of the drug on the tube wall when it is released, thereby improving the release efficiency and quality.

Description

Technical Field

[0001] The invention relates to the technical field of balloon catheters, in particular to a balloon catheter capable of rapidly releasing medicine. Background Art

[0002] The balloon catheter is an interventional medical device that is used once. It simply dilates the blocked blood vessels, restoring their reduced inner diameter to the normal diameter or slightly smaller than normal, but it will definitely be better than before the operation.

[0003] In actual application of existing balloon catheters, medical staff insert the drug balloon through a small 2 mm wound. The balloon is loaded with drugs that dilate blood vessels. After reaching the site of the lesion, the balloon is expanded so that the drugs can stick to the site of the lesion. The balloon is then placed at the site of coronary artery stenosis. After the drug is released, the artery will be expanded. Since the drug balloon cannot place the implanted device in the coronary artery, it may lead to insufficient support force, and blood vessel stenosis may occur again compared to the stent. Secondly, when administering drugs at the site of the lesion, due to the blood scouring of the blood vessels or the solubility problems of the stent itself in the vascular environment, after the balloon catheter carries the drugs, the scouring of blood flow or the scratching of the inner membrane of the blood vessel wall will take away part of the drugs carried. As a result, after reaching the site of the lesion, the remaining amount of drugs in the balloon is insufficient, making it difficult to control the accuracy of drug administration, affecting vasodilation and treatment effects.

[0004] In view of this, the present invention proposes a balloon catheter capable of rapidly releasing drugs to solve the above problems. Summary of the invention

[0005] The purpose of this section is to summarize some aspects of embodiments of the present invention and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this section and the specification abstract and the invention title of this application to avoid blurring the purpose of this section, the specification abstract and the invention title, and such simplifications or omissions cannot be used to limit the scope of the present invention.

[0006] The present invention provides a balloon catheter capable of rapidly releasing drugs, and the specific scheme is as follows:

[0007] A balloon catheter capable of rapidly releasing drugs, comprising a rapid drug delivery component and a transit positioning component, wherein the rapid drug delivery component comprises a drug delivery balloon body, both ends of the drug delivery balloon body are covered with air matching sets, the inner sides of the two air matching sets are interspersed with a catheter, the catheter is interspersed with the drug delivery balloon body, and an inner lining component is arranged inside the drug delivery balloon body;

[0008] The transfer positioning component includes an auxiliary gas disk, the inner wall of the auxiliary gas disk is fixedly connected with a guide sleeve and a guide port opened on the upper part of the guide sleeve, the interior of the auxiliary gas disk is laterally provided with an isolation sheet engaged with the guide sleeve, the upper part of the inner cavity of the auxiliary gas disk is a diversion chamber, the inner cavity of the auxiliary gas disk is fixedly installed with a reset sleeve, the inner cavity of the auxiliary gas disk is rotatably installed with a traction component, the inner cavity of the auxiliary gas disk is rotatably installed with a film rolling rubber roller, and the outer surface of the drug delivery balloon body is provided with a protective component.

[0009] As a preferred solution of the balloon catheter capable of rapidly releasing drugs of the present invention, a guide wire is provided inside the catheter for insertion and movement.

[0010] As a preferred solution of the balloon catheter capable of rapidly releasing drugs described in the present invention, the traction assembly comprises a traction roller rotatably installed in the inner cavity of the auxiliary air disk, the traction roller is rotatably connected with the reset sleeve, the traction roller is rollingly arranged with the film rolling rubber roller, and the traction roller is made of anti-slip material.

[0011] As a preferred solution of the balloon catheter capable of rapidly releasing drugs of the present invention, the inner wall of the auxiliary gas disk is fixedly connected with a guide seat, the guide seat is located in the diversion chamber, and the guide seat is rotatably connected with the traction roller.

[0012] As a preferred solution of the balloon catheter capable of rapidly releasing drugs described in the present invention, a traction blade is rotatably mounted in the middle of the guide seat, both ends of the traction blade are fixedly connected to traction rollers, and the guide opening corresponds to the traction blade.

[0013] As a preferred embodiment of the balloon catheter capable of rapidly releasing drugs described in the present invention, the protective component includes a protective film wound on the outer surface of a film-rolling rubber roller, one end of the auxiliary air disc is provided with a ring opening corresponding to the protective film, and the protective film is used in conjunction with the drug delivery balloon body.

[0014] As a preferred embodiment of the balloon catheter capable of rapidly releasing drugs described in the present invention, a plurality of drainage ports are provided on one end wall of the auxiliary gas disk, a drainage tube is provided inside the drainage port, and the plurality of drainage tubes are respectively connected to the shunt chamber.

[0015] As a preferred embodiment of the balloon catheter capable of rapidly releasing drugs described in the present invention, the lining component comprises a lining mesh bag arranged inside the drug delivery balloon body, the outer surface of the lining mesh bag is provided with a plurality of arc-shaped protrusions equidistantly arranged in an annular manner, and the catheter and the lining mesh bag are interlaced.

[0016] As a preferred solution of the balloon catheter capable of rapidly releasing drugs of the present invention, an air valve is arranged in the middle of the auxiliary air disc, and the air valve is fitted with the air matching set.

[0017] The beneficial effects of the present invention are:

[0018] (1) In the present invention, the blood flowing in the blood vessel is connected through the drainage port and then flows into the shunt chamber. When the blood flows from the outer wall of the guide sleeve into the guide port, the traction blade is impacted and circulated, so that the connected traction roller is driven to rotate. The rotation of the traction roller can drive the film rolling rubber roller to follow the rotation, thereby rolling up the protective film coated on the outer wall of the drug delivery balloon body, so that the protective film is separated by force and gradually peeled off from the protective film as the drug delivery balloon body expands until the protective film is completely retracted. At this time, the drug delivery balloon body is fully expanded and completely contacts the plaque on the blood vessel wall, and the drug carried outside the drug delivery balloon body is adhered to the narrow lesion position, which effectively avoids the loss of drug during balloon intervention, improves the transfer efficiency of drug in the blood vessel wall, and has high accuracy of drug delivery and good use effect.

[0019] (2) In the present invention, the balloon catheter is inserted into the narrowed part of the coronary artery through a small incision of two millimeters, and the auxiliary gas disk is expanded by delivering gas through the gas valve, so that it gradually becomes filled. After the expansion is completed, it will collide with the blood vessel wall or the narrow contracted blood vessel plaque, which is beneficial to prevent the balloon from slipping when releasing the drug and limit the balloon.

[0020] (3) In the present invention, the blood is guided by the guide seat and discharged into the connected drainage tube through the drainage port, and then flows out through another transit positioning component, so that when the balloon is filled and the drug is administered, the blood can flow normally in the blood vessels, avoiding blockage causing ischemia or a series of surgical complications, and improving the quality of drug release.

[0021] (4) In the present invention, when the gas enters through the inner mesh balloon to expand, the gas will be discharged into the medicine balloon body through the through holes on the inner mesh balloon. The discharge of gas will cause the airflow in the inner mesh balloon to fluctuate, thereby continuously impacting the medicine balloon body, causing it to fluctuate, thereby accelerating the release efficiency of the drug at the vascular plaque. After the medicine balloon body and the inner mesh balloon are filled, the arc-shaped protrusion will conflict with the inner membrane of the medicine balloon body, thereby forming some corrugations at the conflicting position between the medicine balloon body and the blood clot plaque, so as to facilitate the slip release of the drug and prevent drug accumulation. The drug at the slower dissolving position will be washed away when the balloon is withdrawn, thereby improving the integrity of the drug release and ensuring the opening of the lumen.

[0022] Other features and advantages of the present invention will be described in the following description, and part of them will become obvious from the description, or will be understood by practicing the present invention. The purpose and other advantages of the present invention can be realized and obtained by the structures particularly pointed out in the written description and the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative labor.

[0024] in:

[0025] Figure 1 The figure is a schematic diagram of the overall structure of the balloon catheter capable of rapidly releasing drugs according to the present invention.

[0026] Figure 2 The figure is a schematic cross-sectional structure diagram of a transfer positioning component of a balloon catheter capable of rapidly releasing drugs according to the present invention.

[0027] Figure 3 The figure is a schematic diagram of the internal structure of the auxiliary gas disc of the balloon catheter capable of rapidly releasing drugs according to the present invention.

[0028] Figure 4 It is a schematic diagram of the semi-section structure of the balloon catheter capable of rapidly releasing drugs of the present invention.

[0029] Figure 5 The invention relates to a balloon catheter capable of rapidly releasing drugs. Figure 3 Schematic diagram of the internal structure.

[0030] Figure 6 It is a schematic side view of the structure of the balloon catheter capable of rapidly releasing drugs according to the present invention.

[0031] Figure 7 It is a schematic diagram of a half-section structure of an auxiliary gas disk of a balloon catheter capable of rapidly releasing drugs according to the present invention.

[0032] Figure 8 It is a schematic diagram of the internal top view of the auxiliary gas disk of the balloon catheter capable of rapidly releasing drugs of the present invention;

[0033] Fig. 9 This is a top view of the auxiliary gas disk.

[0034] In the figure:

[0035] 1. Rapid drug delivery components;

[0036] 110. drug delivery balloon body; 120. air matching device; 130. catheter; 140. guide wire; 150. air valve;

[0037] 2. Transit positioning component;

[0038] 210, auxiliary gas disk; 211, drainage port; 220, drainage tube; 221, drainage port;

[0039] 3. Protection components;

[0040] 310, protective film; 320, film rolling rubber roller; 330, guide port; 340, isolation sheet; 350, diversion chamber; 360, guide sleeve;

[0041] 4. Traction components;

[0042] 410, traction roller; 420, guide seat; 430, traction blade; 440, reset sleeve;

[0043] 5. Lining components;

[0044] 510, inner mesh bag; 520, arc-shaped protrusion. DETAILED DESCRIPTION

[0045] In order to better understand the above technical solution, the above technical solution will be described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0046] like Figure 1 and Fig. 9 As shown, the present invention provides a balloon catheter capable of rapidly releasing drugs, comprising a rapid drug delivery component 1 and a transit positioning component 2, wherein the rapid drug delivery component 1 comprises a drug delivery balloon body 110, both ends of the drug delivery balloon body 110 are provided with gas matching sets 120, the inner sides of the two gas matching sets 120 are interlaced and movably provided with a catheter 130, the catheter 130 is interlaced with the drug delivery balloon body 110, and the inner side of the drug delivery balloon body 110 is provided with an inner lining component 5;

[0047] The transit positioning component 2 includes an auxiliary gas disc 210, the inner wall of which is fixedly connected with a guide sleeve 360 ​​and a guide port 330 opened on the upper part of the guide sleeve 360, an isolation sheet 340 which is interlocked with the guide sleeve 360 ​​is transversely arranged inside the auxiliary gas disc 210, the upper part of the inner cavity of the auxiliary gas disc 210 is a diversion chamber 350, a reset sleeve 440 is fixedly installed in the inner cavity of the auxiliary gas disc 210, a traction component 4 is rotatably installed in the inner cavity of the auxiliary gas disc 210, a film rolling rubber roller 320 is rotatably installed in the inner cavity of the auxiliary gas disc 210, a protective component 3 is arranged on the outer surface of the drug delivery balloon body 110, a guide wire 140 is movably arranged inside the catheter 130, and an air valve 150 is arranged in the middle of the auxiliary gas disc 210, and the air valve 150 is fitted with the air matching 120.

[0048] In this embodiment, the balloon catheter is inserted through the wound and placed in the narrowed lesion site of the arterial blood vessel. Then, gas is delivered through the air valve 150 to expand the auxiliary gas disc 210 first, and then the drug-delivering balloon body 110 is expanded, so that it gradually becomes filled. After the auxiliary gas disc 210 is expanded, it will conflict with the blood vessel wall or the narrow contracted blood vessel plaque. After the auxiliary gas disc 210 is expanded, the drainage port 211 becomes open, which can prevent the balloon from slipping when releasing the drug.

[0049] Example 2

[0050] like Figure 2 , Figure 3 and Figure 5 ,as well as Figure 8 As shown, on the basis of Example 1, the present invention provides a technical solution: the traction component 4 includes a traction roller 410 rotatably installed in the inner cavity of the auxiliary gas disc 210, the traction roller 410 is rotatably connected with the reset sleeve 440, the traction roller 410 is arranged to roll with the film rolling rubber roller 320, the traction roller 410 is made of non-slip material, the inner wall of the auxiliary gas disc 210 is fixedly linked with a guide seat 420, the guide seat 420 is located in the diversion chamber 350, the guide seat 420 is rotatably connected with the traction roller 410, and the middle part of the guide seat 420 is rotatably installed with a traction blade 4 30, both ends of the traction blade 430 are fixedly connected to the traction roller 410, the guide port 330 corresponds to the traction blade 430, a plurality of drainage ports 221 are provided on one end wall of the auxiliary gas disk 210, a drainage tube 220 is provided on the inner side of the drainage port 221, and the plurality of drainage tubes 220 are respectively connected to the diversion chamber 350, the protective component 3 includes a protective film 310 wound on the outer surface of the film rolling roller 320, a ring port corresponding to the protective film 310 is provided at one end of the auxiliary gas disk 210, and the protective film 310 is used in conjunction with the drug delivery balloon body 110.

[0051] In this embodiment, the blood is diverted into the guide port 330 along the guide sleeve 360 ​​through the drainage port 211, and the blood entering the guide port 330 impacts the traction blade 430, so that the traction blade 430 rotates and drives the traction roller 410 to rotate accordingly, thereby driving the film rolling rubber roller 320 to rotate accordingly, and the protective film 310 coated on the outer wall of the drug delivery balloon body 110 can be rolled up. After the protective film 310 is pulled toward both ends, it is separated from the midline of the drug delivery balloon body 110, and as the drug delivery balloon body 110 expands, it gradually peels off from the protective film 310 until the protective film 310 is completely retracted, at which time the drug delivery balloon body 110 is fully expanded and contacts the plaque on the blood vessel wall, and the drug can be completely adhered and released to the lesion site, effectively avoiding drug loss during balloon intervention, improving the transfer efficiency of the drug in the blood vessel wall, and achieving high drug administration accuracy and good use effect. Blood flows from the bottom of the guide seat 420 to the drainage port 221, and flows along the drainage tube 220 connected to the drainage port 221 to the transfer positioning component 2 at the other end to continue flowing. After the drug administration balloon body 110 expands the blood vessel, the blood can maintain a circulation state, preventing the drug administration balloon body 110 from seriously blocking the blood vessel after expansion, causing myocardial ischemia, and causing surgical complications.

[0052] Example 3

[0053] like Figure 4 As shown, based on Example 2, the present invention provides a technical solution: the lining component 5 includes a lining mesh bag 510 arranged inside the drug delivery balloon body 110, and the outer surface of the lining mesh bag 510 is annularly and equidistantly provided with a plurality of arc-shaped protrusions 520, and the catheter 130 and the lining mesh bag 510 are interspersed.

[0054] In this embodiment, the lining mesh balloon 510 is inflated and expanded, and then the gas is discharged into the drug delivery balloon body 110 through the through holes on the lining mesh balloon 510. As the gas enters and is released, the lining mesh balloon 510 will fluctuate, affecting the airflow inside the drug delivery balloon body 110 and causing some shaking of the drug on the drug delivery balloon body 110, thereby accelerating the release efficiency of the drug at the lesion site. After the drug delivery balloon body 110 and the lining mesh balloon 510 are filled, the arc-shaped protrusion 520 provided on the outer surface of the lining mesh balloon 510 will conflict with the inner membrane of the drug delivery balloon body 110, thereby forming some corrugations at the conflicting position between the drug delivery balloon body 110 and the vascular plaque, so as to facilitate the slip release of the drug and prevent the problem of drug accumulation.

[0055] The working principle of the drying device for foam production is described in detail below.

[0056] like Figure 1-9As shown, 1. The user first inserts the balloon catheter through a small incision of two millimeters, and the balloon is loaded with a drug for dilating blood vessels. Then, the balloon is placed at the narrowed part of the coronary artery. The gas is delivered through the air valve 150 to first expand the auxiliary gas disc 210, and then the drug-drug balloon body 110 is expanded, so that it gradually becomes a filled state. Then, after the auxiliary gas disc 210 is expanded, it will conflict with the blood vessel wall or the narrow contracted blood vessel plaque. After the auxiliary gas disc 210 is expanded, the drainage port 211 becomes an open state, and blood flows from the drainage port 211 into the shunt chamber 350. As the blood flows in, the blood flows along the outer wall of the guide sleeve 360 ​​to the guide port 330. The blood entering the guide port 330 impacts the upper part of the traction blade 430, causing it to rotate and drive The traction roller 410 rotates accordingly, and the film rolling rubber roller 320 can be driven to rotate accordingly under the rotation of the traction roller 410. When the film rolling rubber roller 320 rotates, the protective film 310 coated on the outer wall of the drug delivery balloon body 110 is rolled up. After the protective film 310 is pulled toward both ends, it is separated from the midline of the drug delivery balloon body 110. As the drug delivery balloon body 110 expands, it gradually peels off from the protective film 310 until the protective film 310 is completely retracted. At this time, the drug delivery balloon body 110 is fully expanded and contacts the plaque on the blood vessel wall, and the carried drug can be completely attached to the lesion site, effectively avoiding the loss of drug during the balloon intervention process, improving the transfer efficiency of the drug in the blood vessel wall, and achieving high drug delivery accuracy, good use effect, and preventing the balloon from slipping when releasing the drug.

[0057] 2. After that, the blood flows from the bottom of the guide seat 420 to the drainage port 221, and flows along the drainage tube 220 connected to the drainage port 221 to the transfer positioning component 2 at the other end to continue to flow. After the drug-delivery balloon body 110 expands the blood vessels, the blood can maintain a circulating state to prevent the drug-delivery balloon body 110 from seriously blocking the blood vessels after expansion, causing myocardial ischemia and causing surgical complications. After the balloon is expanded and the drug is released, the gas inside is released in time to make it in a deflated state and then draw it back to complete the entire drug-delivery operation.

[0058] 3. When the drug-delivery balloon body 110 is expanded, the gas will first expand the lining mesh balloon 510 inside the drug-delivery balloon body 110, and then the gas will be discharged into the drug-delivery balloon body 110 through the through holes opened in the lining mesh balloon 510. At this time, the lining mesh balloon 510 will fluctuate with the entry and release of gas, which will affect the airflow inside the drug-delivery balloon body 110 and continuously shake the drug on the drug-delivery balloon body 110, thereby accelerating the release efficiency of the drug at the vascular plaque. After the drug-delivery balloon body 110 and the lining mesh balloon 510 are filled, the arc-shaped protrusions 520 arranged on the outer surface of the lining mesh balloon 510 will conflict with the inner membrane of the drug-delivery balloon body 110, thereby forming some corrugated states at the conflicting position between the drug-delivery balloon body 110 and the vascular plaque, so as to facilitate the slip release of the drug and prevent drug accumulation. The drug at the slower dissolving position will be washed away when the balloon is withdrawn, thereby improving the integrity of drug release and ensuring the opening of the lumen.

[0059] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of the present invention is defined by the attached claims and their equivalents.

Claims

1. A balloon catheter capable of rapidly releasing a drug, comprising a rapid drug delivery component (1) and a transit positioning component (2), characterized in that: The rapid drug delivery component (1) comprises a drug delivery balloon body (110), both ends of which are provided with air matching sets (120), the inner sides of the two air matching sets (120) are provided with a catheter (130) which is interlaced and movably arranged, the catheter (130) is interlaced with the drug delivery balloon body (110), and the interior of the drug delivery balloon body (110) is provided with an inner lining component (5); The transfer positioning component (2) comprises an auxiliary gas disc (210), the inner wall of the auxiliary gas disc (210) is fixedly connected with a guide sleeve (360), and a guide opening (330) is provided on the upper part of the guide sleeve (360), the interior of the auxiliary gas disc (210) is transversely provided with an isolation sheet (340) which is engaged with the guide sleeve (360), the upper part of the inner cavity of the auxiliary gas disc (210) is a diversion chamber (350), the inner cavity of the auxiliary gas disc (210) is fixedly installed with a reset sleeve (440), the inner cavity of the auxiliary gas disc (210) is rotatably installed with a traction component (4), the inner cavity of the auxiliary gas disc (210) is rotatably installed with a film rolling rubber roller (320), and the outer surface of the drug delivery balloon body (110) is provided with a protective component (3); A guide wire (140) is movably arranged inside the catheter (130); The traction assembly (4) comprises a traction roller (410) rotatably mounted in the inner cavity of the auxiliary air disc (210), the traction roller (410) and the reset sleeve (440) being interlaced and rotatably connected, the traction roller (410) and the film rolling rubber roller (320) being arranged to roll with each other, and the traction roller (410) is made of a non-slip material; The inner wall of the auxiliary gas disk (210) is fixedly connected with a guide seat (420), the guide seat (420) is located in the diversion chamber (350), and the guide seat (420) is rotatably connected to the traction roller (410); A traction blade (430) is rotatably mounted in the middle of the guide seat (420), both ends of the traction blade (430) are fixedly connected to the traction roller (410), and the guide opening (330) corresponds to the traction blade (430); The protective component (3) comprises a protective film (310) wound on the outer surface of a film rolling rubber roller (320); one end of the auxiliary gas disc (210) is provided with a ring opening corresponding to the protective film (310); the protective film (310) is used in conjunction with the drug delivery balloon body (110); A plurality of drainage ports (221) are provided on one end wall of the auxiliary gas disk (210), a drainage pipe (220) is provided inside the drainage port (221), and the plurality of drainage pipes (220) are respectively connected to the flow distribution chamber (350); The lining assembly (5) comprises a lining mesh bag (510) arranged inside the drug delivery balloon body (110), the outer surface of the lining mesh bag (510) is provided with a plurality of arc-shaped protrusions (520) arranged in an annular manner and at equal intervals, and the catheter (130) and the lining mesh bag (510) are interlaced with each other; An air valve (150) is provided in the middle of the auxiliary air disc (210), and the air valve (150) is fitted with the air matching set (120).

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