An LED light formula for treating skin aging, light source and its application

Abstract

The application discloses an LED light formula for treating skin aging, a light source and application thereof, relates to the technical field of phototherapy and photohealth, and belongs to the technical field of phototherapy and photohealth. ‑2 ·s ‑1 The total photon flux density of the LED light formula is 240-300 mu mol m 2 The total irradiance of the LED light formula is 70-80 W / m 2 ; wherein, according to the percentage of the total photon flux density, the yellow light is 30-40%, and the red light is 60-70%; according to the percentage of the total irradiance, the yellow light is 20-30%, the red light is 35-45%, and the infrared light is 35-40%. The LED light formula can effectively reduce skin wrinkles, improve skin texture, skin color and pigmentation, prevent trans-epidermal water loss, and improve the water content of the stratum corneum, so as to achieve the effect of improving skin aging.

Description

TECHNICAL FIELD

[0001] The present application belongs to the field of phototherapy and photomedicine, and particularly relates to an LED light formula for treating skin aging, a light source and application thereof. BACKGROUND

[0002] Skin is the first line of defense of the body, playing an important role in resisting various external invasions, maintaining internal environment homeostasis and protecting physiological functions. Skin aging is a multi-factor process, often accompanied by endogenous natural aging and exogenous aging. The former refers to natural aging, and the latter mainly refers to skin damage caused by external factors. Skin photoaging is the result of the combined action of natural aging and external factors. After exposure to ultraviolet radiation, skin can cause oxidative stress, inflammatory response and immune response, leading to skin damage, such as roughness, thickening and dryness of the exposed part of the skin, skin relaxation, deepening and thickening of wrinkles, local excessive pigmentation or capillary dilation, and even various benign or malignant tumors (such as solar keratosis, squamous cell carcinoma, malignant melanoma, etc.).

[0003] Studies have found that red light has the effects of relieving pigmentation, preventing sunburn and anti-inflammatory. Infrared light has the effect of reducing the risk of epidermal thermal damage, regulating fibroblast proliferation and adhesion, and stimulating dermal collagen regeneration and remodeling, making the skin tight and having the effect of skin rejuvenation, and is usually used in combination with other wavelengths of light. Yellow light has the functions of repairing wounds, inducing fibroblast proliferation, enhancing skin immunity and improving skin elasticity.

[0004] However, the mainstream of yellow light phototherapy light sources at present is mainly AlGaInP yellow light LED light source and fluorescent powder light source, and the spectral half-spectral range is 570-610nm. The AlGaInP yellow light LED light source has the disadvantages of low luminous efficiency and poor thermal stability. In phototherapy, poor thermal stability will result in low light flux maintenance rate, thereby affecting the treatment effect, and the requirement of high energy density of phototherapy cannot be met; the fluorescent powder light source has the problems of wide spectrum and low color purity, and cannot achieve precise treatment, and the fluorescent powder will also age with the use time, and reliability problems such as light efficiency decline, color temperature drift and blue light leakage are easy to occur.

[0005] At present, the LED device packaging lens of phototherapy equipment is mainly a spherical cap lens. The beam angle of the LED packaging module cannot meet the requirement of ideal spatial spectrum distribution in the treatment process, and secondary free-form lens design is needed to solve the problem of precise control of the light pattern of the LED device of phototherapy equipment, and the secondary free-form lens design will reduce the light efficiency of the LED light source. SUMMARY

[0006] The present application aims to at least solve one of the technical problems existing in the prior art, and provide an LED light formula for treating skin aging, a light source and application thereof.

[0007] The technical solution of the present application is as follows:

[0008] In a first aspect, the present application provides an LED light formula for treating skin aging,

[0009] The LED light formula is composed of yellow light, red light and infrared light;

[0010] The total amount of photon flux density of the LED light formula is 240-300 μmol·m -2 ·s -1 The total amount of irradiance of the LED light formula is 70-80 W / m 2 ;

[0011] According to the percentage of the total amount of photon flux density, the yellow light is 30-40%, and the red light is 60-70%;

[0012] According to the percentage of the total amount of irradiance, the yellow light is 20%-30%, the red light is 35%-45%, and the infrared light is 35%-40%.

[0013] Alternatively, according to the percentage of the total amount of photon flux density, the yellow light is 30-35%, and the red light is 65-70%;

[0014] According to the percentage of the total amount of irradiance, the yellow light is 20%-25%, the red light is 40%-45%, and the infrared light is 35%-40%.

[0015] Alternatively, according to the percentage of the total amount of photon flux density, the yellow light is 33.45%, and the red light is 66.54%;

[0016] According to the percentage of the total amount of irradiance, the yellow light is 21.69%, the red light is 43.15%, and the infrared light is 35.16%.

[0017] Alternatively, the yellow light is selected from a silicon-based GaN yellow light LED light source;

[0018] The half-peak spectral range of the yellow light is 530-595 nm, the half-peak spectral range of the red light is 600-690 nm, and the half-peak spectral range of the infrared light is 780-980 nm.

[0019] Alternatively, the half-peak spectral range of the yellow light is 550-590 nm, the half-peak spectral range of the red light is 610-650 nm, and the half-peak spectral range of the infrared light is 830-870 nm.

[0020] In a second aspect, the present application provides an LED light source for treating skin aging, wherein the LED light source comprises the LED light formula.

[0021] Optionally, the LED light source is in a form of a multi-chip integrated package or a single-chip package.

[0022] The LED light source in the multi-chip integrated package comprises at least one yellow LED chip, at least one red LED chip, at least one infrared LED chip, a die-bonding layer, a substrate, a gold wire and a primary optical lens, the at least one yellow LED chip, the at least one red LED chip and the at least one infrared LED chip are mechanically connected to the substrate through the die-bonding layer respectively, the at least one yellow LED chip, the at least one red LED chip and the at least one infrared LED chip are electrically connected to the substrate through the gold wire respectively, and the primary optical lens seals the at least one yellow LED chip, the at least one red LED chip, the at least one infrared LED chip, the die-bonding layer and the gold wire on the substrate.

[0023] The LED light source in the single-chip package comprises at least one yellow LED single-chip lamp bead, at least one red LED single-chip lamp bead and at least one infrared LED single-chip lamp bead, the at least one yellow LED single-chip lamp bead comprises a yellow LED chip, a die-bonding layer, a substrate, a gold wire and a primary optical lens, the at least one red LED single-chip lamp bead comprises a red LED chip, a die-bonding layer, a substrate, a gold wire and a primary optical lens, and the at least one infrared LED single-chip lamp bead comprises an infrared LED chip, a die-bonding layer, a substrate, a gold wire and a primary optical lens; the yellow LED chip, the red LED chip and the infrared LED chip are mechanically connected to the substrate through the die-bonding layer respectively, the yellow LED chip, the red LED chip and the infrared LED chip are electrically connected to the substrate through the gold wire respectively, and the primary optical lens seals the yellow LED chip, the red LED chip, the infrared LED chip, the die-bonding layer and the gold wire on the substrate.

[0024] The primary optical lens material is at least one of silicone, epoxy resin or polyurethane; and the primary optical lens is a free-form lens, and the free-form lens has a beam angle range of 30°-90°.

[0025] In a third aspect, the present application provides an application of the light formula or the light source in light medical and light health products.

[0026] The present application has at least one of the following beneficial effects:

[0027] The application provides an LED light formula for treating skin aging, a light source and application thereof. BRIEF DESCRIPTION OF DRAWINGS

[0028] Figure 1 Fig. 1 is a schematic diagram of a single-chip packaging structure of an LED light source for treating skin aging according to an embodiment of the application;

[0029] Figure 2 Fig. 2 is a front view of a primary free-form lens lamp bead sample of an LED light source for treating skin aging according to an embodiment of the application, wherein (a) is a 30° free-form lens lamp bead, (b) is a 45° free-form lens lamp bead, and (c) is a 60° free-form lens lamp bead;

[0030] Figure 3 Fig. 3 is a light distribution curve of a primary free-form lens lamp bead of an LED light source for treating skin aging according to an embodiment of the application;

[0031] Figure 4 Fig. 4 is a spectrum diagram of light radiated by an LED light source for treating skin aging according to an embodiment of the application;

[0032] Figure 5 Fig. 5 is a schematic diagram of a multi-chip integrated packaging structure of an LED light source for treating skin aging according to an embodiment of the application;

[0033] Figure 6 Fig. 6 is a schematic diagram of a position arrangement of a yellow light LED chip, a red light LED chip and an infrared light LED chip packaged in a three-in-one manner according to an embodiment of the application, wherein Y is a yellow light LED chip, R is a red light LED chip, and IR is an infrared light LED chip. DETAILED DESCRIPTION

[0034] In order to make the technical problems solved by the application, technical solutions and beneficial effects clearer, the application will be further described in detail below with reference to the drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the application and not used to limit the application.

[0035] The application specifically adopts the following technical solutions:

[0036] The application provides an LED light formula for treating skin aging.

[0037] The application provides an LED light source capable of implementing the LED light formula.

[0038] The application also provides application of the above LED light formula.

[0039] To achieve the object of the present application, an embodiment of the present application provides an LED light formula for treating skin aging, which is composed of the following components:

[0040] The LED light formula is composed of yellow light, red light and infrared light, and the total amount of photon flux density of the LED light formula is 240-300 μmol·m -2 -1 The total amount of irradiance of the LED light formula is 70-80 W / m 2 ;

[0041] According to the percentage of photon flux density, the components of the LED light formula are: yellow light 30-40%, red light 60-70%.

[0042] According to the percentage of irradiance, the components of the LED light formula are: yellow light 20%-30%, red light 35%-45%, and infrared light 35%-40%.

[0043] In the field of LED light medical treatment, the main index parameters include irradiance, time and irradiation dose, and the relationship among the three is: irradiance x time = irradiation dose. Among them, the irradiance can be controlled by the current, but the irradiation dose is not necessarily the larger the better or the smaller the better. The photon flux density (PPFD) refers to the light flux density in the photosynthetically active radiation, which represents the number of light quanta per unit time per unit area in the wavelength range of 400-700 nm. In the prior art, PPFD is mainly used for the research on the photosynthesis of plants under artificial light and sunlight, and has not been found to be used for skin treatment.

[0044] The applicant has found through a large amount of research that when the LED light formula is composed of yellow light, red light and infrared light, and the total amount of irradiance of the LED light formula is 70-80 W / m 2 , and the total amount of photon flux density of the LED light formula is 240-300 μmol·m -2 -1 , the skin wrinkles can be effectively reduced, the skin texture, skin color and pigmentation can be improved, the trans-epidermal water loss can be prevented, and the water content of the stratum corneum can be improved, so as to achieve the effect of improving skin aging.

[0045] The applicant has further found that when the LED light formula is still composed of yellow light, red light and infrared light, but the total amount of irradiance of the LED light formula is not in the range of 70-80 W / m 2 , and the total amount of photon flux density of the LED light formula is not in the range of 240-300 μmol·m -2 -1 , the effect of improving skin aging of the LED light formula is obviously poorer than that of the LED light formula of the present application. ​​​

[0046] In some embodiments of the present application, the LED light formula for treating skin aging, according to the percentage of photon flux density, the components of the LED light formula are: yellow light 30-35%, red light 65-70%; according to the percentage of irradiance, the components of the LED light formula are: yellow light 20%-25%, red light 40%-45%, infrared light 35%-40%.

[0047] In some embodiments of the present application, the LED light formula for treating skin aging, according to the percentage of photon flux density, the components of the LED light formula are: yellow light 33.45%, red light 66.54%; according to the percentage of irradiance, the components of the LED light formula are: yellow light 21.69%, red light 43.15%, infrared light 35.16%.

[0048] In some embodiments of the present application, the half-peak spectral range of the yellow light is 530-595nm, the half-peak spectral range of the red light is 600-690nm, and the half-peak spectral range of the infrared light is 780-980nm.

[0049] In some embodiments of the present application, the half-peak spectral range of the yellow light is 550-590nm, the half-peak spectral range of the red light is 610-650nm, and the half-peak spectral range of the infrared light is 830-870nm.

[0050] To achieve the purpose of the present application, another embodiment of the present application provides an LED light source capable of realizing the LED light formula, which comprises the following structure:

[0051] The packaging structure of the LED light source is at least one of plastic packaging, ceramic packaging and chip-on-board packaging; the packaging form of the LED light source is multi-chip integrated packaging or single-chip packaging; and the substrate is a plastic support, a ceramic substrate, an aluminum substrate or a copper substrate.

[0052] The present application provides an LED light source capable of realizing the above-mentioned LED light formula, and the beam angle of the LED packaging module of the LED light source can meet the ideal spatial spectral distribution requirement in the treatment process, without the need for secondary free-form lens design.

[0053] In some embodiments of the present application, the LED light source for treating skin aging, the multi-chip integrated package LED light source comprises at least one yellow LED chip, one red LED chip, one infrared LED chip, a die bonding layer, a substrate, a gold wire and a primary optical lens; the single-chip packaged LED light source comprises at least one yellow LED single-chip lamp bead, one red LED single-chip lamp bead and one infrared LED single-chip lamp bead, and one LED single-chip lamp bead comprises an LED chip, a die bonding layer, a substrate, a gold wire and a primary optical lens, wherein the LED chip is a yellow LED chip or a red LED chip or an infrared LED chip; the LED chip is mechanically connected to the substrate through the die bonding layer, and the LED chip is electrically conducted to the substrate through the gold wire; and the primary optical lens seals the LED chip on the substrate; and the yellow LED chip used is a silicon-based GaN yellow LED chip with a half-peak spectral range of 550-590 nm.

[0054] The present application first proposes a silicon-based GaN yellow LED light source as a yellow light phototherapy light source, which has a half-peak spectral range of 550-590 nm, high light efficiency and good thermal stability, and solves the problems of insufficient high energy density and low spectral precision of the current mainstream yellow light phototherapy light source, thereby meeting the demand for yellow light in phototherapy.

[0055] In some embodiments of the present application, the LED light source for treating skin aging, the primary optical lens material is silicone, epoxy resin or polyurethane; and the primary optical lens is a free-form surface lens, and the beam angle range of the free-form surface lens is 30°-90°.

[0056] The primary free-form surface lens packaging module proposed in the present application can effectively improve the energy utilization rate and realize uniform light energy distribution of irregular local skin at different irradiation distances. The primary free-form surface lens packaging module proposed in the present application can realize light type regulation, and the beam angle range of the primary free-form surface lens is 30°-90°. Compared with ordinary ball cap lens lamp beads, the free-form surface lens lamp bead greatly improves the central light intensity and the target plane central energy density.

[0057] In some embodiments of the present application, the LED light source for treating skin aging, the LED light source is connected to a power module, and the multi-channel current output by a current adjusting module in the power module is input into the yellow LED chip, the red LED chip and the infrared LED chip in the LED light source for treating skin aging through adjustment of the current adjusting module.

[0058] To achieve the purpose of the present application, the present application further provides an application of the above-mentioned LED light source, which comprises:

[0059] The application of a light formula or light source for treating skin aging in light medical and light health products.

[0060] The light formula or light source in the application can be used in light medical and light health products to achieve the effect of improving skin aging, providing a new way for the treatment of skin aging.

[0061] The application will be further described in detail below with specific examples, but the application is not limited to the following specific examples.

[0062] Example 1

[0063] In the application, the light source for treating skin aging belongs to a phosphor-free type light source, and the packaging form of the LED light source is single-chip packaging, which is composed of a yellow light LED single-chip lamp bead, a red light LED single-chip lamp bead and an infrared light LED single-chip lamp bead. The yellow light LED chip used is a silicon-based GaN yellow light LED chip with a half-peak spectral range of 550-590 nm, the red light LED chip used has a half-peak spectral range of 610-650 nm, and the infrared light LED chip used has a half-peak spectral range of 830-870 nm. The total amount of the photon flux density of the LED light source is 248.59 μmol·m -2 ·s -1 , and the total amount of irradiance is 74.907 W / m 2 . According to the percentage of photon flux density: yellow light LED 33.45%, red light LED 66.54%. According to the percentage of irradiance: yellow light LED 21.69%, red light LED 43.15%, and infrared LED 35.16%.

[0064] In order to better illustrate the structure of the LED light source, as shown in Figure 1 , the LED light source adopts a primary free-form lens packaging module capable of realizing light type regulation. In the single-chip packaged LED light source, one single-chip lamp bead includes an LED chip 2, a die bonding layer 3, a gold wire 4, a ceramic substrate 5 and a primary optical lens 1. The LED chip 2 realizes mechanical connection with the ceramic substrate 5 through the die bonding layer 3 and realizes electrical conduction with the ceramic substrate 5 through the gold wire 4. The primary optical lens 1 seals the LED chip 2, the die bonding layer 3 and the gold wire 4 on the ceramic substrate 5, realizing mechanical protection and light extraction of the LED chip. The LED chip is a yellow light LED chip or a red light LED chip or an infrared light LED chip.

[0065] The primary optical lens is one of the structures of the LED packaging device, which is directly covered (or bonded) on the LED chip holder and becomes a whole with the LED. The LED chip theoretically emits light in 360°, but in fact, the light emitting angle of the chip is limited after the chip is placed on the LED holder for fixation and packaging. Through the primary optical lens, all light can be effectively converged, and different light emitting angles such as 180°, 160°, 140°, 120°, 90°, 60°, etc. can be obtained. The primary optical lens in the embodiment is a free-form surface lens.

[0066] In order to further illustrate the structure of the packaging module, as shown in (a) of Figure 2 In the embodiment, the LED light source adopts a primary free-form surface lens packaging module capable of realizing light type regulation, and the light beam angle of the primary free-form surface lens is 30°. Compared with the ball cap lens lamp bead, the central light intensity of the 30° free-form surface lens lamp bead is increased by 2.8 times, and the central energy density of the target plane is increased by 2.9 times. Figure 3 The light distribution curve of the 30° free-form surface lens lamp bead is shown in (b) of Figure 3 The free-form surface lens controls most of the light of the LED light source within-15° to 15°, that is, the light beam angle is 30°, and the central light intensity is increased under the condition that the light power is unchanged, so as to meet the requirement of high energy density of phototherapy and realize accurate treatment of the diseased area.

[0067] Figure 4 The spectrum diagram of the light source of the embodiment of the application is shown in (c) of Figure 4 The yellow light half-peak spectrum range is 550-590nm, the red light half-peak spectrum range is 610-650nm, and the infrared light half-peak spectrum range is 830-870nm. The light power ratio of yellow light, red light and infrared light is 3:6:5.

[0068] The LED light source in the embodiment of the application is applied to a large array lamp for treating skin aging.

[0069] Embodiment 2

[0070] In the embodiment, the light source for treating skin aging belongs to a no-fluorescent powder type light source, and the packaging form of the LED light source is a multi-chip integrated packaging. The single lamp bead is composed of one yellow light LED chip, one red light LED chip and one infrared light LED chip.

[0071] In order to better illustrate the structure of the LED light source, as shown in (a) of Figure 5As shown in the LED light source, a multi-chip lamp bead includes a yellow light LED chip, a red light LED chip, an infrared light LED chip, a die bonding layer 3, a gold wire 4, a ceramic substrate 5 and a primary optical lens 1, wherein the yellow light LED chip, the red light LED chip and the infrared light LED chip are respectively mechanically connected to the ceramic substrate 5 through the die bonding layer 3 and electrically conducted to the ceramic substrate 5 through the gold wire 4, the primary optical lens 1 seals the yellow light LED chip, the red light LED chip, the infrared light LED chip, the die bonding layer 3 and the gold wire 4 on the ceramic substrate 5, and realizes mechanical protection and light extraction of the yellow light LED chip, the red light LED chip and the infrared light LED chip. The arrangement of the yellow light LED chip, the red light LED chip and the infrared light LED chip is as shown in the figure, wherein R represents the red light LED chip, Y represents the yellow light LED chip, and IR represents the yellow light LED chip. Figure 6

[0072] The primary optical lens is one of the structures of the LED packaging device, which is directly covered (or bonded) on the LED chip support and becomes a whole with the LED. Theoretically, the LED chip emits light in 360°, but in fact, the light emitting angle of the chip is limited after the chip is placed on the LED support for fixation and packaging. Through the primary optical lens, all light can be effectively collected, and different light emitting angles such as 180°, 160°, 140°, 120°, 90° and 60° can be obtained. In this embodiment, the primary optical lens is a free-form surface lens.

[0073] The rest is the same as example 1.

[0074] Example 3

[0075] In this embodiment, the red light LED chip used in the LED light source has a half-peak spectral range of 590-630 nm, the infrared light LED chip used has a half-peak spectral range of 780-820 nm, and the rest is the same as example 1.

[0076] Example 4

[0077] In this embodiment, the red light LED chip used in the LED light source has a half-peak spectral range of 650-690 nm, the infrared light LED chip used has a half-peak spectral range of 940-980 nm, and the rest is the same as example 1.

[0078] Example 5

[0079] In this embodiment, the application involved is a cosmetic mirror, and the rest is the same as example 1.

[0080] Example 6

[0081] ​In this embodiment, the application involved is a bathroom heater, and the rest is the same as in embodiment 2.

[0082] Example 7

[0083] In this embodiment, as Figure 2 As shown in (b) in this embodiment, the LED light source adopts a primary freeform lens packaging module that can realize light pattern control. The beam angle of the primary freeform lens is 45°, and the rest is the same as in embodiment 1.

[0084] Example 8

[0085] In this embodiment, as Figure 2 As shown in (c), in this embodiment, the LED light source adopts a primary freeform lens packaging module that can realize light pattern control. The beam angle of the primary freeform lens is 60°, and the rest is the same as in embodiment 1.

[0086] Comparative Example 1

[0087] The only difference from Example 1 is that the power ratio of the yellow LED, red LED, and infrared LED is 5:6:5, and the rest is the same as Example 1.

[0088] Comparative Example 2

[0089] The only difference from Example 1 is that the power ratio of the yellow LED, red LED, and infrared LED is 1:6:5, and the rest is the same as Example 1.

[0090] Comparative Example 3

[0091] The only difference from Example 1 is that the power ratio of the yellow LED, red LED, and infrared LED is 3:3:5, and the rest is the same as Example 1.

[0092] Comparative Example 4

[0093] The only difference from Example 1 is that the power ratio of yellow LED, red LED, and infrared LED is 3:9:5, and the rest is the same as Example 1.

[0094] Comparative Example 5

[0095] The only difference from Example 1 is that the power ratio of yellow LED, red LED, and infrared LED is 3:6:3, and the rest is the same as Example 1.

[0096] Comparative Example 6

[0097] The only difference from Example 1 is that the power ratio of yellow LED, red LED, and infrared LED is 3:6:7, and the rest is the same as Example 1.

[0098] Comparative Example 7

[0099] The difference from example 1 is only that the yellow light adopts AlGaInP yellow light LED light source, and the rest is the same as example 1.

[0100] Comparative example 8

[0101] The difference from example 1 is only that the primary optical lens 1 is replaced by a common spherical cap lens, and the rest is the same as example 1.

[0102] Comparative example 9

[0103] The difference from example 1 is only that the primary free-form lens beam angle is 15°, and the rest is the same as example 1.

[0104] Test and analysis:

[0105] Take the light source in example 1 of the application as an example, the specific treatment process is:

[0106] 1. The experimental material sources are as follows:

[0107] (1) Light source for treating skin aging: obtained by matching the light powers of a silicon-based GaN yellow light LED with a half-peak spectral range of 550-590 nm, a red light LED with a half-peak spectral range of 610-650 nm, and an infrared light LED with a half-peak spectral range of 830-870 nm at a ratio of 3:6:5, the total photon flux density is 248.59 μmol·m -2 ·s -1 , the light source irradiance is 74.907 W / m 2 , and the irradiation energy is 6.74 J / cm 2 .

[0108] (2) The main instruments and equipment are shown in Table 1:

[0109] Table 1

[0110]

[0111] 2. According to the inclusion criteria and exclusion criteria, the subjects were admitted:

[0112] (1) Inclusion criteria: ① Meet the aging skin grading: Fitzpatrick skin type is III-IV type; ② Age 30-65 years old, and willing to accept the treatment of this study; ③ The overall score of facial aging (GSP score) is 3-4 points. ④ The working environment is in the room.

[0113] (2) Exclusion criteria: ① There are other skin diseases or other factors affecting the treatment effect; ② Within half a year, relevant cosmetic treatments such as laser, radio frequency, photon, botulinum toxin injection, hyaluronic acid injection, and chemical peeling were performed; ③ Photosensitive or within half a year, photosensitive drugs such as retinoids and hydroquinone were taken; ④ There are endocrine diseases or severe chronic diseases affecting skin physiology (such as anemia, systemic lupus erythematosus, liver and kidney dysfunction, etc.); ⑤ Pregnant or lactating women; ⑥ Scarring; ⑦ History of mental illness; ⑧ History of other systemic diseases; ⑨ Excessive expectations.

[0114] A total of 17 subjects were enrolled, with a gender ratio of 7 / 10, an age of (41.94±6.41) years, 9 cases of Fitzpatrick skin type III and 8 cases of type IV, 7 cases of GSP score 3 and 10 cases of score 4; There was no statistically significant difference in the comparison of general data of the subjects (P>0.05).

[0115] Table 2 General data of subjects

[0116] Subject characteristics

[0117]

[0118] 3. Detection of skin spots, wrinkles, texture and brown spots before and after light exposure.

[0119] (1) Experimental method: The research object first takes the VISIA facial skin image analyzer for photo analysis. The analysis includes the following skin quality parameters: spot, wrinkle, texture, and brown spot. The higher the number, the more serious the degree of skin aging. Then the patients were treated with skin cleaning before treatment, and protective cover was worn on the eyes.

[0120] (2) Treatment method: The light source with a light power ratio of 3:6:5, yellow light LED with a half-peak spectral range of 550-590 nm, red light LED with a half-peak spectral range of 610-650 nm, and infrared light LED with a half-peak spectral range of 830-870 nm were used for irradiation. The irradiation time was 15 minutes, and the irradiation distance was 25 cm from the edge of the table. The instrument was placed vertically at an angle of 65° with the table surface, and the vertical line distance between the highest point of the nose bridge in the middle of the face and the midpoint of the instrument plane was 15 cm.

[0121] (3) Irradiation frequency: Irradiation was performed once every other day, three times a week. All subjects received treatment at the experimental center using a light source for treating skin aging for five weeks. After treatment, subjects were instructed to: ① The treatment process does not affect the cleanliness of the treated area, but should avoid using hot water, soap, facial cleanser, shower gel, and other irritating substances as much as possible, and ensure that the washing is gentle and avoid vigorous rubbing; ② Avoid spicy and irritating foods, and avoid smoking and alcohol; ③ Take physical sun protection measures when going out during the treatment period.

[0122] (4) Feature Detection: After each week of treatment, photos were analyzed using the VISIA facial skin image analyzer. SPSS 26.0 software was used for data processing, and t-tests were performed on the quantitative data. Data are expressed as (x ± s), and P < 0.05 indicates statistical significance. The statistical results of the experimental features are shown in Table 3. The results show that after 5 weeks of treatment, the spots, wrinkles, texture, and brown spots of the subjects improved, and the improvement was statistically significant.

[0123] Table 3. Comparison of statistical results of spots, wrinkles, textures, and brown spots in subjects before and after light exposure.

[0124]

[0125] 4. Measurement of facial stratum corneum moisture content, melanin, transepidermal water loss, and gloss before and after light exposure for the subjects.

[0126] (1) Experimental method: The subjects were first tested using a non-invasive skin physiological function tester from CK (Germany) to measure the stratum corneum moisture content, melanin, transepidermal water loss, and luster of their faces. The lower the stratum corneum moisture content and the lower the luster, the higher the transepidermal water loss and melanin, the worse the skin condition.

[0127] (2) Treatment method: The same treatment method as that used for detecting spots, wrinkles, textures and brown spots on the skin of subjects before and after light exposure.

[0128] (3) Irradiation frequency: the same as the irradiation frequency used for detecting skin spots, wrinkles, textures and brown spots before and after light exposure of the subjects.

[0129] (4) Feature Detection: Facial features were examined using a non-invasive skin physiological function testing instrument from CK (Germany) during the middle and end of treatment. SPSS 26.0 software was used for data processing. Quantitative data were analyzed using t-tests and expressed as (x ± s). P < 0.05 indicated statistical significance. The statistical results of the experimental features are shown in Table 4. The results showed that after 5 weeks of treatment, the scores for stratum corneum moisture content and gloss increased, while the scores for melanin and transepidermal water loss decreased.

[0130] Table 4. Comparison of statistical results of stratum corneum moisture content, gloss, melanin, and transepidermal water loss before and after light exposure in subjects.

[0131]

[0132] Therefore, the light source in Example 1 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, indicating that the light source of the present application can effectively reduce skin wrinkles, improve skin texture, skin color, and pigmentation, prevent trans-epidermal water loss, increase stratum corneum water content, and achieve the effect of improving skin aging.

[0133] Similarly, the treatment effects of the light sources in Examples 2 to 8 and Comparative Examples 1 to 9 were tested using the above method, and the results are as follows:

[0134] The light source in Example 2 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, and the treatment effect was comparable to that of Example 1.

[0135] The light source in Example 3 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, and the treatment effect was slightly worse than that of Example 1, which may be because the half-peak spectral range of the red light LED chip and the infrared light LED chip affected the treatment effect.

[0136] The light source in Example 4 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, and the treatment effect was slightly worse than that of Example 1, which may be because the half-peak spectral range of the red light LED chip and the infrared light LED chip affected the treatment effect.

[0137] The light source in Example 5 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, and the treatment effect was comparable to that of Example 1, indicating that the arrangement form of the light source did not affect the treatment effect.

[0138] The light source in Example 6 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, and the treatment effect was comparable to that of Example 1, indicating that the arrangement form of the light source did not affect the treatment effect.

[0139] The light source in Example 7 improved the spots, wrinkles, texture, brown spots, stratum corneum water content, and gloss of the face of the subject, and was able to reduce the melanin of the face, and the treatment effect was comparable to that of Example 1.

[0140] The light source in Example 8 improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to reduce the melanin on the face, and the treatment effect was comparable to Example 1.

[0141] Comparative Example 1 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect was significantly worse than Example 1, which can be because the proportion of yellow light LEDs in the three types of light was too high, affecting the treatment effect.

[0142] Comparative Example 2 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect was significantly worse than Example 1, which can be because the proportion of yellow light LEDs in the three types of light was too low, affecting the treatment effect.

[0143] Comparative Example 3 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect of wrinkles and texture was significantly worse than Example 1, which can be because the proportion of red light LEDs in the three types of light was too low, affecting the treatment effect.

[0144] Comparative Example 4 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect of stratum corneum moisture content and gloss was significantly worse than Example 1, which can be because the proportion of red light LEDs in the three types of light was too high, affecting the treatment effect.

[0145] Comparative Example 5 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect was significantly worse than Example 1, which can be because the proportion of infrared light LEDs in the three types of light was too low, affecting the treatment effect.

[0146] Comparative Example 6 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect was significantly worse than Example 1, which can be because the proportion of infrared light LEDs in the three types of light was too high, affecting the treatment effect.

[0147] Comparative Example 7 slightly improved the spots, wrinkles, texture, brown spots, stratum corneum moisture content, and gloss of the subject's face, and was able to slightly reduce the melanin on the face, but the treatment effect was slightly worse than Example 1, which can be because the AlGaInP yellow light LED light source had low luminous efficiency and poor thermal stability, resulting in low light flux maintenance rate and affecting the treatment effect.

[0148] The spot, wrinkle, texture, brown spot, stratum corneum moisture content and gloss of the face of the subject in Comparative Example 8 are slightly improved, and the melanin of the face is slightly reduced, but the treatment effect is obviously decreased compared with Example 1, which may be because the beam angle of the LED packaging module formed by the ordinary ball cap lens cannot meet the requirements of high energy density and precise treatment of the diseased area in the treatment process, thereby affecting the treatment effect.

[0149] The spot, wrinkle, texture, brown spot, stratum corneum moisture content and gloss of the face of the subject in Comparative Example 9 are slightly improved, and the melanin of the face is slightly reduced, but the treatment effect is obviously decreased compared with Example 1, which may be because the beam angle range of the one free-form lens affects the treatment effect.

[0150] The above is only a preferred specific embodiment of the present application, but the protection scope of the present application is not limited thereto, any person skilled in the art within the technical range disclosed by the present application, according to the technical scheme and the inventive concept of the present application, equivalent replacement or change, should be covered within the protection scope of the present application.

Claims

1. An LED light formula, characterized in that, the LED light formula is composed of yellow light, red light and infrared light; The total photon flux density of the LED light recipe is 240 pmol m -2 ·s -1 -300 pmol m -2 ·s -1 -80 W / m 2 -80 W / m 2 ; wherein, according to the percentage of the total amount of photon flux density: yellow light 33.45%, red light 66.54%; According to the percentage of the total amount of irradiance: yellow light 21.69%, red light 43.15%, infrared light 35.16%; The half-peak spectral range of the yellow light is 550-590 nm, the half-peak spectral range of the red light is 610-650 nm, and the half-peak spectral range of the infrared light is 830-870 nm; The yellow light selects a silicon-based GaN yellow light LED light source.

2. An LED light source for treating skin aging, characterized in that, The LED light source comprises the LED light formula of claim 1.

3. The LED light source of claim 2, characterized in that, the packaging form of the LED light source is a multi-chip integrated package; The multi-chip integrated package LED light source comprises at least one yellow light LED chip, at least one red light LED chip, at least one infrared light LED chip, a die bonding layer, a substrate, a gold wire and a primary optical lens, the at least one yellow light LED chip, the at least one red light LED chip and the at least one infrared light LED chip are mechanically connected to the substrate through the die bonding layer respectively, the at least one yellow light LED chip, the at least one red light LED chip and the at least one infrared light LED chip are electrically connected to the substrate through the gold wire respectively, and the primary optical lens seals the at least one yellow light LED chip, the at least one red light LED chip, the at least one infrared light LED chip, the die bonding layer and the gold wire on the substrate.

4. The LED light source of claim 2, characterized in that, the packaging form of the LED light source is a single-chip package; The single-chip packaged LED light source comprises at least one yellow light LED single-chip lamp bead, at least one red light LED single-chip lamp bead and at least one infrared light LED single-chip lamp bead, the at least one yellow light LED single-chip lamp bead comprises a yellow light LED chip, a die bonding layer, a substrate, a gold wire and a primary optical lens, the at least one red light LED single-chip lamp bead comprises a red light LED chip, a die bonding layer, a substrate, a gold wire and a primary optical lens, and the at least one infrared light LED single-chip lamp bead comprises an infrared light LED chip, a die bonding layer, a substrate, a gold wire and a primary optical lens; the yellow light LED chip, the red light LED chip and the infrared light LED chip are mechanically connected to the substrate through the die bonding layer respectively, the yellow light LED chip, the red light LED chip and the infrared light LED chip are electrically connected to the substrate through the gold wire respectively, and the primary optical lens seals the yellow light LED chip, the red light LED chip, the infrared light LED chip, the die bonding layer and the gold wire on the substrate.

5. The LED light source according to claim 3 or 4, characterized in that The material of the primary optical lens is at least one of silica gel, epoxy resin or polyurethane; the primary optical lens is a free-form lens, and the beam angle range of the free-form lens is 30°-90°.

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