An insecticide bait composition containing piperic acid derivative compounds

Abstract

The present invention discloses an insecticide bait composition containing a piperic acid derivative compound. The compounded insecticide bait comprises active ingredients A and B, wherein A is a piperic acid derivative compound and B is one of fipronil, indoxacarb, dinotefuran, hydrazone, or imidacloprid. The weight ratio of A to B is 20:1 to 1:10. Because the piperic acid derivative compound is a brand-new insecticide ingredient with a novel mechanism of action, a good lethal effect, and no repellency to sanitary pests, the composition can delay the resistance of single insecticide baits, improve the control effect, and prolong the lasting effect.

Description

Technical Field

[0001] The present invention relates to a sanitary insecticide bait composition containing a piperic acid derivative compound (Compound I-72). The active ingredient of the insecticide bait composition is a combination of a piperic acid derivative compound (Compound I-72 for short) and a compound selected from the group consisting of fipronil, indoxacarb, dinotefuran, hydrazone and imidacloprid. Background Art

[0002] As living standards continue to improve, people have higher expectations for their living environment. Cockroaches, ants, and fire ants are pests that cause long-term distress and harm to residents, and the annual financial investment in their control is increasing year by year. Currently, baits are a key product in this control effort. Because cockroaches, ants, and fire ants are difficult to completely eliminate, pesticide applicators have to increase the dosage and frequency of their applications. This leads to a significant increase in pesticide resistance, increasing application costs, and increasing the workload for applicators. Therefore, the market urgently needs a new generation of baits to alleviate the current challenges in the pest control market.

[0003] Fipronil is a phenylpyrazole insecticide with a broad insecticidal spectrum. It is mainly a stomach poison, with both contact and systemic effects. Its mechanism of action is to act on the γ-aminobutyric acid (GABA) receptors in the insect central nervous system to block the opening of cellular chloride ion channels, interfere with the central nervous system, and cause the insect's nerves and muscles to become overexcited and die.

[0004] Indoxacarb is a broad-spectrum oxadiazine insecticide that blocks the sodium ion channels in insect nerve cells, causing the nerve cells to lose their normal function and die. It has stomach poison and contact killing effects.

[0005] Imidacloprid is a first-generation neonicotinoid compound and an acetylcholine receptor stimulant. It binds to acetylcholine receptors, destroys the central nervous conduction of pests, and causes the pests to die of excitement. It has contact, stomach poison and systemic effects.

[0006] Dinotefuran is a third-generation neonicotinoid compound and an acetylcholine receptor stimulant. It has a broad insecticidal spectrum with contact, stomach, and systemic effects. Compared with traditional neonicotinoid insecticides, it has higher insecticidal activity and greater systemic and penetrating activity.

[0007] Hydrahydrazone mainly acts on the mitochondria in insects, causing metabolic system disorders and respiratory system failure in the pests, and eventually death from flaccid paralysis.

[0008] As a new type of insecticide, a piperic acid derivative compound (Compound I-72) is a derivative of a piperic acid compound that has a good killing effect on cockroaches, ants, and fire ants. The piperic acid derivative compound (Compound I-72) is compounded with one of fipronil, indoxacarb, dinotefuran, hydrazone, and imidacloprid to solve the current problem of resistant pests being difficult to disinfect. On the one hand, the two have different mechanisms of action, and the compounding has no cross-resistance, which can solve the problem of resistance of sanitary pests to fipronil, indoxacarb, dinotefuran, hydrazone, and imidacloprid; on the other hand, through research, it was found that the compounding of the two can improve the control effect of sanitary pests, and is a compounding drug technology with good market prospects. Summary of the Invention

[0009] Based on the harm caused by cockroaches, ants and red imported fire ants, and the technical difficulties caused by the emergence of pesticide-resistant pests, the present invention provides an insecticide bait composition containing a piperic acid derivative compound. The piperic acid derivative compound (Compound I-72) is compounded with any one of fipronil, indoxacarb, dinotefuran, hydrazone and imidacloprid to form an insecticide bait, which has a synergistic effect on killing cockroaches, ants and red imported fire ants, delays the emergence of resistance, and improves the efficiency of pest control.

[0010] In order to achieve the above object, the present invention adopts the following technical solutions:

[0011] An insecticide bait composition containing a piperic acid derivative compound, wherein the active ingredients are component A and component B, and the active ingredients account for 0.03% to 3% of the total weight of the insecticide bait composition by weight, and the rest are auxiliary materials;

[0012] The component A is a piperic acid derivative compound (Compound I-72), and the component B is any one of fipronil, indoxacarb, dinotefuran, hydrazone, and imidacloprid;

[0013] Among them, the piperic acid derivative compound (Compound I-72) has the following structural formula:

[0014]

[0015] In the above technical solution, the weight ratio of component A to component B is 20:1 to 1:10.

[0016] In the above technical solution, the weight ratio of component A to component B is preferably 10:1 to 1:5.

[0017] In the above technical solution, the auxiliary materials include sugars, moisturizing agents, oils, attractant additives and carriers, and the insecticide bait composition includes the following raw materials in weight percentage: 0.03% to 3% active ingredients, 0.1% to 20% sugars, 0.1% to 20% moisturizing agents, 0.1% to 15% oils, 0.01% to 5% attractant additives, 1% to 50% carriers, and 5% to 75% water.

[0018] In the above technical solution, the sugar is any one of white sugar, glucose, sucrose, maltose, honey, lactose, galactose, fructose, corn syrup, brown sugar, and caramel, or a mixture of two or more of the above in any proportion.

[0019] In the above technical solution, the moisturizing agent is any one of propylene glycol, glycerol, and sorbitol, or a mixture of two or more of them in any proportion.

[0020] In the above technical solution, the oil is any one of soybean oil, sesame oil, peanut oil, corn oil, butter, and tallow, or a mixture of two or more of them in any proportion.

[0021] In the above technical solution, the attractant additive is any one of indole, tricosene, fruit flavor, egg yolk powder, milk flavor, vanillin, brown sugar flavor, betaine, cockroach pheromone, soy sauce ketone, and onion extract, or a mixture of two or more in any proportion.

[0022] In the above technical solution, the carrier is any one of dextrin, flour, soybean flour, oat flour, toasted bran flour, broad bean flour, fish meal, meat meal, cellulose derivatives, xanthan gum, gelatin, polyethylene glycol, polyvinyl pyrrolidone, and carboxyethylene copolymer, or a mixture of two or more in any proportion.

[0023] In the above technical solution, the bait formulations of the insecticide bait composition include but are not limited to: granular bait, gel bait, and bait box.

[0024] The present invention also provides an application of the insecticide bait composition in preventing and controlling sanitary pests.

[0025] In the above technical solution, the targets of the insecticide bait composition for controlling sanitary pests are cockroaches, ants and fire ants.

[0026] Compared with the existing technology, it has the following characteristics:

[0027] The insecticide bait composition described in the present invention uses a new ingredient insecticide original drug piperic acid derivative compound (compound I-72) and is compounded with any one of the existing high-efficiency insecticides fipronil, indoxacarb, dinotefuran, hydrazone, and imidacloprid. It has a synergistic effect on killing cockroaches, ants, and red imported fire ants, delays the problem of resistance easily caused by single drug use, and improves the efficiency of pest control. At the same time, the present invention has certain advantages in attracting pests through its unique formula combination, is easier to attract pests to feed, and can also improve the efficiency of pest control. DETAILED DESCRIPTION

[0028] The following describes in detail the specific embodiments of the technical solution of the present invention, but the present invention can be implemented in many different forms and is not limited to the following description. On the contrary, these embodiments are provided to make the disclosure of the present invention more fully understood.

[0029] The preparation method of the bait in each embodiment of the present invention is as follows:

[0030] Preparation method of granular bait: Mix sugar, moisturizer, attractant additive and water, stir thoroughly, and set aside after becoming a uniform liquid phase. Mix oil, carrier and original medicine to form a solid phase, add the liquid phase to the solid phase and stir. After stirring evenly, use a granulator to granulate or make it into blocks, and dry it to obtain granular bait.

[0031] Preparation method of glue bait: Mix sugar, moisturizer, attractant additive, carrier and water, stir thoroughly, add oil and original medicine after becoming a uniform phase, continue stirring, use high-speed shear emulsifier to shear if necessary, and package after mixing evenly to make glue bait.

[0032] Preparation method of bait box: Mix sugar, moisturizer, attractant additive and water, stir thoroughly, and set aside after it becomes a uniform liquid phase, mix oil, carrier and original medicine to form a solid phase, add the liquid phase to the solid phase and stir, then prepare it into a specific shape and put it into a specific box or directly squeeze it into a specific box to make a bait box.

[0033] The present invention will be described below in conjunction with specific embodiments:

[0034] Preparation Example 1: 0.21% piperic acid derivative compound (Compound I-72)·Fipronil granular bait

[0035] The invention comprises the following raw materials in weight percentage: 0.2% of piperic acid derivative compound (Compound I-72), 0.01% of fipronil, 20% of white sugar, 0.1% of glycerol, 0.1% of brown sugar essence, 5% of sesame oil, 50% of flour and 24.59% of water.

[0036] Preparation Example 2: 0.03% piperic acid derivative compound (Compound I-72)·Fipronil gel bait

[0037] The invention comprises the following raw materials in weight percentage: 0.01% of piperic acid derivative compound (compound I-72), 0.02% of fipronil, 5% of maltose, 15% of glucose, 20% of propylene glycol, 0.2% of vanillin, 0.1% of soybean oil, 2% of xanthan gum, 0.5% of carboxymethyl cellulose and 57.17% of water.

[0038] Preparation Example 3: 1% piperic acid derivative compound (Compound I-72)·Fipronil bait box

[0039] The invention comprises the following raw materials in weight percentage: 0.8% of piperic acid derivative compound (compound I-72), 0.2% of fipronil, 2% of honey, 8% of fructose, 5% of sorbitol, 0.5% of betaine, 5% of peanut oil, 2% of butter, 12% of meat powder, 10% of dextrin, 15% of wheat bran powder and 39.5% of water.

[0040] Preparation Example 4: 1.1% piperic acid derivative compound (Compound I-72)·Indoxacarb granular bait

[0041] The invention comprises the following raw materials in weight percentage: 0.1% of a piperic acid derivative compound (compound I-72), 1% of indoxacarb, 10% of corn syrup, 2% of brown sugar, 7% of propylene glycol, 0.01% of indole, 2% of corn oil, 35% of soybean powder, 3% of fish meal, 10% of flour and 29.89% of water.

[0042] Preparation Example 5: 2% piperic acid derivative compound (Compound I-72)·Indoxacarb gel bait

[0043] The invention comprises the following raw materials in weight percentage: 1% of a piperic acid derivative compound (compound I-72), 1% of indoxacarb, 15% of sucrose, 5% of lactose, 20% of sorbitol, 0.1% of vanillin, 0.1% of sesame oil, 0.1% of apple essence, 1% of carboxyethylene copolymer, and 56.7% of water.

[0044] Preparation Example 6: 0.8% piperic acid derivative compound (Compound I-72)·Indoxacarb bait box

[0045] The invention comprises the following raw materials in weight percentage: 0.5% of piperic acid derivative compound (compound I-72), 0.3% of indoxacarb, 9% of white sugar, 1% of galactose, 3% of glycerol, 4.8% of egg yolk powder, 0.05% of cockroach pheromone, 0.15% of soy sauce ketone, 8% of soybean oil, 25% of broad bean powder, 0.2% of xanthan gum, 0.05% of gelatin and 47.95% of water.

[0046] Preparation Example 7: 0.1% piperic acid derivative compound (Compound I-72)·Dinotefuran granular bait

[0047] The invention comprises the following raw materials in weight percentage: 0.01% of a piperic acid derivative compound (Compound I-72), 0.09% of dinotefuran, 10% of corn syrup, 5% of glycerol, 0.02% of cockroach pheromone, 2% of butter, 2% of corn oil, 10% of sesame oil, 0.2% of gelatin, 15% of oatmeal powder, 29.8% of flour and 25.88% of water.

[0048] Preparation Example 8: 0.08% piperic acid derivative compound (Compound I-72)·Dinotefuran gel bait

[0049] The invention comprises the following raw materials in weight percentage: 0.07% of piperic acid derivative compound (compound I-72), 0.01% of dinotefuran, 1% of honey, 5% of fructose, 10% of caramel, 10% of propylene glycol, 8% of glycerol, 0.1% of soy sauce ketone, 0.1% of peanut oil, 0.5% of polyvinyl pyrrolidone, 1.4% of xanthan gum, 0.1% of gelatin and 63.72% of water.

[0050] Preparation Example 9: 0.2% piperic acid derivative compound (Compound I-72)·Dinotefuran bait box

[0051] The invention comprises the following raw materials in weight percentage: 0.1% of piperic acid derivative compound (compound I-72), 0.1% of dinotefuran, 6% of glucose, 10% of sorbitol, 0.1% of pineapple flavor, 0.05% of milk flavor, 0.05% of tricosene, 7% of sesame oil, 25% of flour, 10% of soybean powder, 7% of meat powder and 34.6% of water.

[0052] Preparation Example 10: 1% piperic acid derivative compound (Compound I-72)·Hydrahydrazone granular bait

[0053] The invention comprises the following raw materials in weight percentage: 0.7% of piperic acid derivative compound (compound I-72), 0.3% of hydrazone, 1% of galactose, 10% of fructose, 3% of corn syrup, 6% of glycerol, 1% of onion extract, 0.05% of tricosene, 1% of butter, 9% of corn oil, 0.5% of xanthan gum, 20% of broad bean flour, 19.5% of toasted bran flour and 27.95% of water.

[0054] Preparation Example 11: 1.2% piperic acid derivative compound (Compound I-72)·Fluoroant hydrazone glue bait

[0055] The invention comprises the following raw materials in weight percentage: 0.2% of piperic acid derivative compound (compound I-72), 1% of hydrazone, 5% of sucrose, 10% of glucose, 20% of glycerol, 0.1% of milk flavor, 1% of butter, 1% of polyethylene glycol, 2% of xanthan gum, 0.5% of polyvinyl pyrrolidone and 59.2% of water.

[0056] Preparation Example 12: 2.2% piperic acid derivative compound (Compound I-72)·Hydrazone bait box

[0057] The invention comprises the following raw materials in weight percentage: 2% of a piperic acid derivative compound (compound I-72), 0.2% of hydrazone, 5% of brown sugar, 5% of maltose, 10% of sorbitol, 0.2% of vanillin, 5% of sesame oil, 5% of corn oil, 10% of flour, 10% of soybean powder, 15% of fish meal, 8% of oatmeal powder and 24.6% of water.

[0058] Preparation Example 13: 2.5% piperic acid derivative compound (Compound I-72)·Imidacloprid granular bait

[0059] The invention comprises the following raw materials in weight percentage: 0.5% of piperic acid derivative compound (compound I-72), 2% of imidacloprid, 10% of brown sugar, 3% of corn syrup, 2% of propylene glycol, 8% of sorbitol, 0.1% of indole, 0.1% of soy ketone, 3% of sesame oil, 4% of soybean oil, 0.5% of polyvinyl pyrrolidone, 30% of soybean powder, 10% of fish meal and 26.8% of water.

[0060] Preparation Example 14: 1.3% piperic acid derivative compound (Compound I-72)·Imidacloprid gel bait

[0061] The invention comprises the following raw materials in weight percentage: 0.5% of piperic acid derivative compound (compound I-72), 0.8% of imidacloprid, 5% of sucrose, 10% of glucose, 20% of glycerol, 0.1% of vanillin, 0.5% of onion extract, 0.5% of soybean oil, 2% of polyethylene glycol, 12% of dextrin, 2% of xanthan gum, 0.5% of cellulose derivative and 46.1% of water.

[0062] Preparation Example 15: 3% piperic acid derivative compound (Compound I-72)·Imidacloprid bait box

[0063] The invention comprises the following raw materials in weight percentage: 2.8% of piperic acid derivative compound (Compound I-72), 0.2% of imidacloprid, 1% of honey, 8% of glucose, 5% of sorbitol, 0.1% of apple essence, 10% of onion extract, 10% of peanut oil, 15% of flour, 10% of soybean powder, 15% of fish meal and 22.9% of water.

[0064] Comparative Example

[0065] Comparative Example 1

[0066] 2.15% hydrazone gel bait (commercially available)

[0067] Comparative Example 2

[0068] 0.05% fipronil granular bait (commercially available)

[0069] Comparative Example 3

[0070] 1% hydrazone granular bait (commercially available)

[0071] Comparative Example 4

[0072] 1% hydrazone granular bait (preparation method and formula refer to Preparation Example 10)

[0073] Application Examples

[0074] The present invention uses a bait formulation to target cockroaches, ants, and imported imported fire ants (RIFAs) in indoor and field studies. Compared to conventional baits, the formulation demonstrates superior insecticidal activity and significant control efficacy. Those skilled in the art will appreciate that the examples described herein are intended only to facilitate understanding of the present invention and should not be construed as limiting the present invention.

[0075] Application Example 1 Co-toxicity Coefficient Determination

[0076] Test basis: Refer to NY / T1154.7-2006 "Guidelines for Indoor Bioassay of Pesticides - Insecticides Part 7: Determination of Combined Action of Mixtures" for test insects;

[0077] Test target: German cockroaches, 10-15 day old adults, half male and half female.

[0078] Test conditions: temperature 25℃±1℃, relative humidity 65%±5%

[0079] Drugs to be tested:

[0080] 90% piperic acid derivatives (Compound I-72) (Shenyang Sinochem Pesticide Chemical Research and Development Co., Ltd.)

[0081] 95% Fipronil (Jiangsu Youjia Plant Protection Co., Ltd.)

[0082] 70.5% indoxacarb (Jiangsu Youjia Plant Protection Co., Ltd.)

[0083] 98% Dinotefuran (Hubei Shenglong Chemical Co., Ltd.)

[0084] 95% hydrazone (Jiangsu Youjia Plant Protection Co., Ltd.)

[0085] 98% Imidacloprid (Jiangsu Youjia Plant Protection Co., Ltd.)

[0086] Test method:

[0087] The test agent was first dissolved in dichloromethane and serially diluted in a 1:9 ratio with a 0.1% Triton-X100 solution. 1 mL of each diluted solution was added to a 150 mL serum bottle. The bottle was swirled to evenly distribute the solution. The solution was then placed in a fume hood overnight to allow the organic solvent to evaporate. Test insects were then placed in the concentration range that resulted in 100% mortality and 100% survival. Within this range, appropriate concentrations were serially diluted with a 0.1% Triton-X100 solution. 1 mL of each diluted solution was added to a 150 mL serum bottle. The bottle was swirled to evenly distribute the solution. The solution was then placed in a fume hood overnight to allow the organic solvent to evaporate. Vaseline was then applied to the neck of the serum bottle. Twenty test insects were placed in each bottle. The experiment was repeated five times. The corresponding solvent-treated control served as a control. After one hour, all test insects were transferred to a clean container for standard feeding. After 72 hours, the insects were examined and counted for mortality.

[0088] The statistical analysis software SPSS was used to analyze the LC50 of each drug and its 95% confidence limit. The co-toxicity coefficient of the mixture was calculated as follows:

[0089]

[0090] In the formula

[0091] LC50A - median lethal concentration of agent A

[0092] LC50B - median lethal concentration of agent B

[0093] LC50 mixture - the lethal concentration of the mixture of agent A and agent B

[0094] PA--the proportion of agent A in the active ingredients of the mixture

[0095] PB--the proportion of agent B in the active ingredients of the mixture

[0096] A co-toxicity coefficient greater than 120 indicates a synergistic effect, a co-toxicity coefficient between 80-120 indicates an additive effect, and a co-toxicity coefficient less than 80 indicates an antagonistic effect. The test results are shown in the following table

[0097] Table 1 Determination of the co-toxicity coefficient of piperic acid derivatives (Compound I-72) and fipronil (for German cockroaches)

[0098]

[0099]

[0100] As shown in Table 1, when the compound 1877 and fipronil are mixed in a ratio of 20:1 to 1:10, the co-toxicity coefficient against German cockroaches is greater than 100, indicating an additive effect; when the compound 1877 and fipronil are mixed in a ratio of 10:1 to 1:10, the co-toxicity coefficient against German cockroaches is greater than 12, indicating a synergistic effect.

[0101] Table 2 Determination of the co-toxicity coefficient of piperic acid derivatives (Compound I-72) and indoxacarb (against German cockroach)

[0102]

[0103]

[0104] As shown in Table 2, when the compound 1877 and indoxacarb were mixed in a ratio of 20:1 to 1:10, the co-toxicity coefficient against German cockroaches was greater than 100, indicating an additive effect; when the compound 1877 and indoxacarb were mixed in a ratio of 10:1 to 1:5, the co-toxicity coefficient against German cockroaches was greater than 120, indicating a synergistic effect.

[0105] Table 3 Determination of the co-toxicity coefficient of piperic acid derivatives (Compound I-72) and dinotefuran (against German cockroaches)

[0106]

[0107] As shown in Table 3, when the compound 1877 and dinotefuran are mixed in a ratio of 20:1 to 1:10, the co-toxicity coefficient against German cockroaches is greater than 100, indicating an additive effect; when the compound 1877 and dinotefuran are mixed in a ratio of 10:1 to 1:5, the co-toxicity coefficient against German cockroaches is greater than 120, indicating a synergistic effect.

[0108] Table 4 Determination of the co-toxicity coefficient of piperic acid derivatives (Compound I-72) and hydrazone (for German cockroaches)

[0109]

[0110]

[0111] As shown in Table 4, when the compound 1877 and hydrazone were mixed at a ratio of 20:1 to 1:10, the co-toxicity coefficient against German cockroaches was greater than 120, indicating a synergistic effect.

[0112] Table 5 Determination of the co-toxicity coefficient of piperic acid derivatives (Compound I-72) and imidacloprid (for German cockroaches)

[0113]

[0114]

[0115] As shown in Table 5, when the compound 1877 and imidacloprid are mixed at a ratio of 20:1 to 1:10, the co-toxicity coefficient against German cockroaches is greater than 100, indicating an additive effect; when the compound 1877 and imidacloprid are mixed at a ratio of 10:1 to 1:15, the co-toxicity coefficient against German cockroaches is greater than 120, indicating a synergistic effect.

[0116] Application Example 2 Indoor efficacy experiment

[0117] Test targets: German cockroaches (half male and half female), small yellow house ant workers, and red imported fire ant workers

[0118] Test method:

[0119] Cockroach efficacy experiment: Referring to GB / T13917.7-2009 Indoor efficacy test and evaluation of public health insecticides for registered pesticides Part 7: Bait, 30 German cockroaches, half male and half female, were placed in a square box, 2 g of bait was added, and Comparative Example 1 (2.15% hydrazone gel bait, commercially available) was used as a control. The test temperature was 25°C and the humidity was 70%. Three replicates were performed. After 96 hours, the number of dead and live insects was checked and the mortality rate was calculated.

[0120] Ant efficacy test: Referring to GB / T13917.7-2009 Indoor efficacy test and evaluation of public health insecticides for pesticide registration Part 7: Bait, 100 small yellow house ant workers were placed in an enamel square dish with a circle of vaseline on the inner edge, 2 g of bait was added, and the bait of Comparative Example 2 (0.05% fipronil granules, commercially available) was used as a control. The test temperature was 25°C and the humidity was 70%. Three replicates were performed. After 96 hours, the number of dead and alive insects was checked and the mortality rate was calculated.

[0121] Experiment on the efficacy of drugs against red imported fire ants: Worker ants from the same ant nest were lured outdoors with fresh ham sausage slices. 40 captured worker ants were placed in a 500ml beaker with a circle of vaseline on the inner edge of the beaker. 2g of bait was added, and the baits of Comparative Example 3 (1% hydrazone granular bait, commercially available) and Example 4 (1% hydrazone granular bait, homemade) were used as controls. The test temperature was 25°C and the humidity was 70%. Three replicates were performed. After 72 hours, the number of dead and alive insects was checked and the mortality rate was calculated.

[0122] Table 6: Test of the efficacy of the preparation examples on German cockroaches, small yellow house ants, and red imported fire ants

[0123]

[0124]

[0125]

[0126] The test results show that:

[0127] The efficacy of Preparation Examples 1 to 15 against German cockroaches was better than that of Comparative Example 1 (2.15% hydrazone gel bait, commercially available);

[0128] The efficacy of Preparation Examples 1 to 15 against small yellow ants was better than that of Comparative Example 2 (0.05% fipronil granular bait, commercially available);

[0129] The efficacy of Preparation Examples 1 to 15 against red imported fire ants was better than that of Comparative Example 3 (1% hydrazone granular bait, commercially available) and Comparative Example 4 (1% hydrazone granular bait, prepared by referring to Preparation Example 10);

[0130] Comparative Example 4 (1% hydrazone granular bait, the preparation method of which is described in Preparation Example 10) is more effective than Comparative Example 3 (1% hydrazone granular bait, commercially available), indicating that the combination of the present invention has certain advantages in attracting pests.

[0131] The above examples are only for illustrating the technical concept and technical features of the present invention and are not intended to limit the scope of protection of the present invention. Any equivalent transformation or modification made based on the essence of the present invention should be included in the scope of protection of the present invention.

Claims

1. An insecticide bait composition containing a piperic acid derivative compound, characterized in that: The active ingredients are component A and component B, which account for 0.03% to 3% of the total weight of the insecticide bait composition by weight, and the rest are auxiliary materials, which include attractant additives; The component A is a piperic acid derivative compound, and the component B is any one of fipronil, indoxacarb, dinotefuran, hydrazone, and imidacloprid; Wherein, the structural formula of the piperic acid derivative compound is as follows: The attractant additive is any one of indole, tricosene, fruit flavor, egg yolk powder, milk flavor, vanillin, brown sugar flavor, betaine, cockroach pheromone, soy sauce ketone, and onion extract, or a mixture of two or more of the above in any proportion.

2. The insecticide bait composition according to claim 1, characterized in that The weight ratio of component A to component B is 20:1 to 1:

10.

3. The insecticide bait composition according to claim 1, characterized in that The auxiliary materials include sugars, moisturizing agents, oils, attractant additives and carriers. The insecticide bait composition includes the following raw materials in weight percentage: 0.03% to 3% active ingredients, 0.1% to 20% sugars, 0.1% to 20% moisturizing agents, 0.1% to 15% oils, 0.01% to 5% attractant additives, 1% to 50% carriers, and 5% to 75% water.

4. The insecticide bait composition according to claim 3, characterized in that The sugar is any one of white sugar, glucose, sucrose, maltose, honey, lactose, galactose, fructose, corn syrup, brown sugar, and caramel, or a mixture of two or more of the above in any proportion.

5. The insecticide bait composition according to claim 3, characterized in that The moisturizing agent is any one of propylene glycol, glycerol and sorbitol, or a mixture of two or more of them in any proportion.

6. The insecticide bait composition according to claim 3, characterized in that The oil is any one of soybean oil, sesame oil, peanut oil, corn oil, butter, and tallow, or a mixture of two or more of the oils in any proportion.

7. The insecticide bait composition according to claim 3, characterized in that The carrier is any one of dextrin, flour, soybean powder, oat flour, roasted bran powder, broad bean powder, fish meal, meat meal, cellulose derivatives, xanthan gum, gelatin, polyethylene glycol, polyvinyl pyrrolidone, and carboxyethylene copolymer, or a mixture of two or more of the above in any proportion.

8. The insecticide bait composition according to claim 3, characterized in that The bait formulation of the insecticide bait composition is a granular bait, a gel bait or a bait box.

9. Use of the insecticide bait composition according to claim 1 in preventing and controlling sanitary pests, characterized in that: The targets of the insecticide bait composition for controlling sanitary pests are cockroaches, ants and fire ants.

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