Ultrasonic and magnetic traditional Chinese medicine coupling therapeutic apparatus

Abstract

The traditional Chinese medicine modern physical therapy theory is used as guidance, the treatment effect is strongly coupled through the technologies of ultrasonic waves, a magnetic field, magnetized traditional Chinese medicine matched liquid and the like, the matched liquid is preferably selected from ganoderma lucidum, ginseng, oysters, kelp, coix seeds, dandelions, angelica sinensis, poria cocos, chicory, malt, magnetite, Brazil nuts and other medicines, and the microelement zinc is added. Microbial fermentation engineering and a magnetization technology are utilized to enrich chelated trace elements, analyze active peptides, extract traditional Chinese medicine alcohol components and the like, the zinc element displays magnetic moment through a coupling reaction, an efficient coupling treatment effect is formed, and an ultrasonic magnetic traditional Chinese medicine coupling therapeutic instrument is prepared and used for covering prostate and preventing, treating and recovering bone and bone joint diseases and has a wide application prospect. The preparation has the advantages of convenience in use, simplicity in preparation, high bioavailability, no toxic or side effect and the like. The figure 1 is shown in the specification figure.

Description

Technical Field

[0001] The present invention belongs to the field of biomedical medical devices, and mainly relates to an ultrasonic wave, a magnetic field, a magnetizer, a Chinese medicine treatment system (prepared liquid, Chinese medicine tea) and a manufacturing method thereof, which can be used for physical therapy, massage, and Chinese medicine health, including but not limited to enhancing immunity, preventing and treating prostate diseases, and pain in tendons, bones, and joints. Background Art

[0002] The main cause of prostate disease is that as men age, their overall body function declines and their spleen is not nourished. This includes prostatitis, hypertrophy, and hyperplasia. Insufficient energy and nutrient supply will lead to abnormalities in the urinary system, frequent urination, weak urine, decreased sexual function, urethral outlet stenosis, and frequent urination symptoms. Urine passes through the narrow urethra, forming a thin urine stream, bifurcated urine, and even urine obstruction and retention. The cause of prostate hyperplasia is that qi deficiency leads to nerve deficiency, qi dysfunction, blood stasis, and blood stasis blocking the prostate, making it unable to nourish and gradually enlarge. Traditional Chinese medicine has a slow effect in treating prostate diseases. The effect of traditional Chinese medicine plus ultrasonic magnetic therapy will be significantly improved.

[0003] Patients with prostate diseases are weak, and the virus will attack muscles, tendons, bones and joints, causing musculoskeletal soreness, fatigue, neurasthenia, and sclerosis of the elasticity of blood vessel walls. Blood flow is poor, resulting in a decrease in the oxygen-carrying capacity of red blood cells, a sharp drop in blood oxygen saturation, and insufficient blood supply to the heart, lungs and brain, pain in the bones and muscles, nerve damage, and multiple organ failure. This is in line with the characteristics of "epidemic disease", "warm disease" or "arthralgia", "bone arthralgia" and "gout" in traditional Chinese medicine. The disease is located from the outside to the inside, and mostly follows the changes in the upper, middle and lower three burners and the Wei Qi, Ying Qi and blood, causing pain in the bones and joints.

[0004] Most of the existing physical therapy equipment has a single function, such as ultrasonic therapy devices, magnetic therapy devices, etc., and has a complex structure and cumbersome operation. There is a lack of equipment that can be used in conjunction with the traditional Chinese medicine system to massage the body's tissue cells.

[0005] Chinese traditional medicine has a history of thousands of years and has played a good role in the prevention and treatment of prostate diseases. The formulas are mainly aimed at strengthening the body and improving immunity, but there are problems such as slow effect of coupled physical therapy.

[0006] According to relevant data, the trace element "zinc" has the function of promoting growth and development; enhancing the body's cellular immune function, especially the function of phagocytes. However, zinc is a diamagnetic metal, and it is generally difficult to combine with magnetic fields and ultrasound to achieve a combined effect.

[0007] The present invention is guided by the theory of physical therapy and modernization of traditional Chinese medicine, and uses the powerful combined effects of ultrasound, magnetic field, magnetized Chinese medicine and other technologies. According to the theory of traditional Chinese medicine, drugs are selected and trace elements are added. Microbial fermentation engineering and magnetization technology are used to enrich chelated trace elements, analyze active peptides and extract Chinese medicine components. Through "coupling reaction" and magnetization, the zinc element shows magnetic moment, and the hysteresis effect of ultrasound in the magnetic field is used to form an efficient combined effect to make an "ultrasound-magnetic Chinese medicine coupling therapeutic instrument" to activate immune function and enhance the body's immune response ability to cells. It can be used to prevent, treat and recover from muscle and bone joint pain and prostate diseases, and has the advantages of easy use, simple preparation, high bioavailability, reliable efficacy and no toxic side effects. Summary of the invention

[0008] The purpose of the present invention is to provide an ultrasonic magnetic Chinese medicine coupling therapeutic instrument with therapeutic and preventive functions and a preparation method thereof, which is used to prevent and treat pain in the prostate, tendons, bones and joints.

[0009] The technical solution adopted by the present invention to achieve the above-mentioned purpose is to set and connect a magnetic head in the shell of the ultrasonic generator massage head, which is composed of an ultrasonic generator, a magnetic field generator, a magnetizer (water), and a preparation liquid (drinking water, tea, Chinese medicine, etc.). The therapeutic effect of the combined output of the device is exerted on the human body (drinking the preparation liquid magnetized by the magnetizer), and the physical therapy and pharmacological effects are strengthened, the curative effect is improved, and the toxic and side effects are not superimposed. Figure 1 As shown in the functional structure diagram, it consists of an ultrasonic generator, a massage head, a magnetic field generator (magnetic head), a magnetizer, a preparation liquid, and a treatment part of the human body.

[0010] "Ultrasonic generator" is an ultrasonic physiotherapy massage product produced by conventional technology, equipped with an ultrasonic transmitter head (ultrasonic massage head) for massage, as shown in the attached Figure 2 As shown in (2), the frequency is 1-1.5MHz, the effective radiation area is 4.0-8.0 square centimeters, the effective sound intensity is 0.72-1.2W / square centimeter, and the output power is >4W. Ultrasonic waves can be locally emitted to treat diseased parts of the human body without affecting other healthy organs.

[0011] "Magnetic field generator (magnetic head)" as shown in the attached picture Figure 2 As shown, it is made of magnetic material, referred to as the magnetic head (4), cylindrical, with a channel (5) in the middle and lower part, through which the preparation liquid (traditional Chinese medicine tea, coupling agent) can contact the treatment part of the human body, axial magnetization, referring to the international magnetic supplementation safety standard, requiring the magnetic field strength to be 1000-3000GS, the area is consistent with the area of ​​the ultrasonic head, about 4-8 square centimeters, the thickness is determined by the magnetic field strength data, using a neodymium iron boron magnet, the thickness is 1.5 cm, the magnetic head (4) and the ultrasonic massage head (2) are connected by screws, and the aperture can be 3-8 cm. The magnetic head and the ultrasonic head can also be glued (3) or directly welded.

[0012] The ultrasonic and magnetic head parts can be designed with devices that add heating functions.

[0013] The "magnetizer" is made of magnet and stainless steel material, as shown in the attached figure Figure 3 As shown, the shape is set as a tubular cylindrical vessel, a cylindrical magnet (3) is set inside, and a stainless steel water pipe (5) is installed in the axial opening of the center to allow liquid to circulate. The magnetic field strength (radial) is 2600-5000GS and above. The outer periphery is wrapped with a stainless steel skin (4), which can make the peripheral magnetic field very low and safe for the human body. During treatment, the preparation liquid (traditional Chinese medicine tea, drinking water, oral drug liquid, etc.) can be poured into it through the water inlet (1). Under normal temperature conditions, the magnetization flow rate is 2.5M / S, and the magnetic induction intensity is 0.26-0.32T. It is cut along the direction perpendicular to the magnetic field line, and flows out through the water outlet (2) after magnetization, so that people can use it as a matching oral, injection and massage coupling agent during treatment. The zinc-containing traditional Chinese medicine liquid (preparation liquid) can show magnetic moment after magnetization, and form a strong combined attraction with the magnetic field.

[0014] "Preparation liquid (Chinese herbal tea)" is a special beverage made from Chinese herbal medicine and food materials according to the type of disease being treated. About 250-400 ml of the preparation liquid is used at a time. After being magnetized by a magnetizing device, it can be taken orally, injected intramuscularly into the treatment area, and used as a chelating agent between the skin and the skin during massage.

[0015] The "prepared liquid (Chinese medicinal tea)" of the present invention is a special product prepared from Chinese medicinal and edible materials selected according to the type of disease to be treated.

[0016] A liquid (traditional Chinese medicine tea) for ultrasonic magnetic Chinese medicine coupling therapeutic apparatus for preventing and treating prostate diseases and pain in tendons, bones and joints is mainly made of the following raw materials: ganoderma lucidum, ginseng, oyster, kelp, coix seed, dandelion, angelica, Poria cocos, chicory, malt, magnet, Brazil nut, zinc, etc. This formula mainly uses strengthening the body, dispersing stagnation, clearing away heat and removing blood stasis. The main drugs are ganoderma lucidum and ginseng: ganoderma lucidum is sweet, neutral in nature, and can benefit the heart, lungs and liver, replenish qi and calm the mind, relieve cough and asthma, and has the effects of immunoregulation, lowering blood sugar, lowering blood lipids, anti-oxidation, and anti-aging, and can also purify blood and protect liver function; ginseng is warm in nature and sweet in taste, and has the effects of "greatly replenishing vital energy, replenishing the spleen and lungs, calming the mind and increasing intelligence", which can improve the body's resistance to cells, improve the patient's physical condition, and prevent metastasis. The assistant drugs are oyster and kelp: oyster, salty in taste, flat in nature, can nourish yin and suppress yang, soften and disperse nodules, and has the effects of astringency, sedation, detoxification, analgesia and stomach harmonization; kelp, salty in taste, cold in nature, can eliminate phlegm, soften and disperse nodules, promote diuresis and reduce swelling, and is used for goiter, scrofula, testicular swelling and pain, phlegm and edema. The two flavors work synergistically to soften and disperse nodules, resist nodules, resist hyperplasia, and relieve pain and inflammation. The adjuvants are coix seed, dandelion and angelica, which help to remove dampness, relieve heat and nourish blood: coix seed is cool in nature, sweet and light in taste, and can invigorate the spleen and eliminate dampness, eliminate numbness and stop diarrhea, clear away heat and discharge pus, inhibit skeletal muscle contraction, and have the effects of relieving fever, analgesia, anti-inflammatory and enhancing immune function; dandelion is bitter, sweet and cold, and can clear away heat and detoxify, reduce swelling and disperse knots, and promote diuresis and relieve stranguria. It can improve hot stranguria, that is, increased urination frequency, burning urination and painful urination; angelica is sweet and spicy in taste and warm in nature, and "neutralizes" the coldness of dandelion and coix seed, replenishes blood and promotes blood circulation, regulates menstruation and relieves pain, and moisturizes the intestines and relieves constipation. It can replenish blood and warm the meridians, promote blood circulation and relieve pain, inhibit platelet aggregation, resist thrombosis, regulate blood lipids, and can also enhance immunity and moisturize the intestines and relieve dryness. The supporting drugs include Poria cocos, which tastes sweet and light, is neutral in nature, can promote diuresis and eliminate dampness, strengthen the spleen, and calm the mind. It is used for edema and oliguria, phlegm and fluid, palpitations, spleen deficiency and poor appetite, loose stools and diarrhea, restlessness, palpitations and insomnia; chicory, which tastes slightly bitter and salty, is cool in nature, and is used for damp-heat jaundice, stomachache and poor appetite, edema and oliguria. It contains a variety of phenolic acid compounds, such as chicoric acid and caffeic acid, which have multiple pharmacological effects such as lowering uric acid, resisting gout, lowering blood sugar, lowering blood lipids, and improving gastrointestinal metabolic disorders; malt, which is sweet and neutral in nature, can promote qi and digestion, strengthen the spleen and stimulate the appetite, and is used for food stagnation. The invention discloses a kind of Chinese medicine tea, which is a kind of food additive, and is used for treating nausea, vomiting, distending pain in the abdomen, poor appetite due to spleen deficiency, stagnation of liver and pain in the ribs, and pain in the liver and stomach. The magnet is salty in nature and cold in flavor, and can calm the nerves and soothe the nerves, and can calm the liver and suppress yang. The Brazilian nut and the Brazilian chestnut are also known as the Brazilian nut and the abalone fruit, and are foods, and are rich in selenium, magnesium, vitamin B1, vitamin B2, vitamin E, carotene, etc., and have obvious effects on protecting the liver. The rich selenium content can help control the function of the thyroid gland and can also enhance the function of the immune system. Zinc is a food additive, and can enhance the cellular immune function of the body, especially the function of phagocytes. The preparation liquid (Chinese medicine tea) is both a medicine and a food or a health food, and can be used for people's health care to prevent and treat prostate diseases and pain in tendons, bones and joints, and is safe and efficient.

[0017] A liquid (traditional Chinese medicine tea) for ultrasonic magnetic Chinese medicine coupling therapeutic apparatus is prepared from the following raw materials in the following weight ratio:

[0018]

[0019] Most preferably, the optimal weight ratio of the liquid formula of the "ultrasonic magnetic Chinese medicine coupling therapeutic device" of the present invention is:

[0020]

[0021] The present invention also provides a method for preparing the liquid for the "ultrasonic magnetic Chinese medicine coupling therapeutic apparatus", comprising the following steps:

[0022] (1) weighing the raw materials of "lingzhi, ginseng, oyster, kelp, coix seed, dandelion, angelica, tuckahoe, chicory, malt, magnetite, Brazil nut" according to the above formula ratio, mixing, slicing, steaming, cooking, and storing;

[0023] (2) inoculating the above-mentioned matured material with yeast strains and stirring the mixture for fermentation;

[0024] (3) introducing the fermentation liquid into an enzyme for enzymolysis to separate out the polypeptides, inactivating the enzyme, filtering and concentrating the liquid to obtain a polypeptide solution;

[0025] (4) The fermented drug residue is boiled with water, the decoction is combined, mixed with the above-mentioned polypeptide drug solution, filtered, concentrated, and the drug solution is collected to obtain "water-extracted fermented peptide drug solution";

[0026] (5) The fermented medicinal residue is subjected to conventional Ganoderma lucidum fermentation and culture method to produce Ganoderma lucidum-containing substances.

[0027] (6) boiling the Ganoderma lucidum fungus with water, combining the decoctions, filtering and concentrating, collecting the medicinal liquid, and obtaining the "Ganoderma lucidum medicinal liquid";

[0028] (7) adding an enzyme to the above-mentioned Ganoderma lucidum medicinal liquid to perform enzymolysis to parse out the peptides, inactivate the enzyme, filter, and concentrate to obtain the "Ganoderma lucidum peptide medicinal liquid";

[0029] (8) The above-mentioned "water-extracted fermented peptide liquid" and "Ganoderma lucidum peptide liquid" are mixed with zinc powder weighed according to the above-mentioned proportion, stirred and mixed for chelation to form a peptide-zinc chelate, filtered and purified, and filled to obtain the "ultrasonic magnetic Chinese medicine coupling therapeutic device" preparation liquid (Chinese medicine tea).

[0030] The dosage form of the preparation liquid is any dosage form acceptable in pharmaceutical science.

[0031] Preferably, in step (1), add 3 times the amount of water, soak for 3 hours and then steam for 30-45 minutes.

[0032] Preferably, the bacterial species in step (2) of the above preparation method may be probiotics or Pseudomonas denitrificans.

[0033] Preferably, in step (3) of the above preparation method, protease (0.1%) and lipase (0.1%) are added, and enzymolysis is carried out for 4-6 hours at a temperature of 50-61° C., a pH of 5-7.5, and stirring.

[0034] Preferably, when yeast is introduced into the mixture in the preparation method (2), the introduction ratio is 1-1.5% by weight, the pH value is 6-8, the temperature is 20-31° C., and the fermentation process is performed for 1.5-2 hours.

[0035] Preferably, in step (4) of the above preparation method, the medicinal residue is further steamed with water, the first time for 35-45 minutes and the second time for 0.5-1.0 hour, and the decoctions are combined.

[0036] Preferably, in the above preparation method (6), "adding water to steam the Ganoderma lucidum fungus again" the first time is 35 minutes and the second time is 45 minutes.

[0037] Preferably, in the above preparation method (7), "adding enzymes to the above Ganoderma lucidum medicinal liquid" means adding protease (0.1%) and lipase (0.1%), and performing enzymolysis for 4-6 hours at a temperature of 50-61°C, pH 5-7.5 and stirring.

[0038] The production method of the preparation liquid (traditional Chinese medicine tea) of the present invention is characterized in that the microbial fermentation technology is used to "enrich nutrition, adjust fragrance, chelate elements, form peptide zinc ion bonds and peptide selenium ion bonds", which can increase the polypeptide content. According to the test, the polypeptide content is increased by more than 60%; it can be converted into "Ganoderma lucidum polysaccharide". The preparation liquid can be used to produce health food, beverages, tea, etc., and its function is to improve immunity and prevent and treat diseases such as prostate, tendon and bone joint pain.

[0039] The liquid (traditional Chinese medicine tea) used in the "ultrasonic magnetic Chinese medicine coupling therapeutic device" can be used to manufacture drugs and medical devices for the treatment of prostate diseases. It can be used to develop special medical foods or functional (health) foods, or beverages (tea) that can be antioxidant, improve immunity, prevent and treat aging, and can be used for massage and health care to prevent and treat muscle, bone and joint pain.

[0040] When the present invention is used for prevention and treatment, the preparation liquid is first poured into a magnetizer for magnetization, a portion is reserved as a coupling agent, a portion is directly taken orally, and a portion is injected into the tendons, bones, joints or prostate. After the patient drinks the magnetized oral liquid for 30-45 minutes, the ultrasonic magnetic head is used to massage the treatment part of the body (the magnetic head has the preparation liquid as a coupling agent), and the ultrasonic magnetized Chinese medicine tea coupling effect can be used to treat and alleviate the disease and protect the healthy cells in the body.

[0041] Scientific research has confirmed that most substances in human tissue are diamagnetic substances, while free radical substances are paramagnetic substances with higher magnetic permeability than human body. Under the same magnetic field conditions, free radicals are more sensitive.

[0042] The preparation liquid described in the present invention refers to "Chinese herbal tea", in which zinc element is added to form "peptide zinc ion bond", which can show magnetic moment after magnetization. According to our experiments, the magnetic permeability of the preparation liquid is more than 1 times that of drinking water and the preparation liquid without zinc addition (the formula of the present invention). It can form a strong combined therapeutic effect with the ultrasonic magnetic field and has a high therapeutic index.

[0043] The principle of the present invention is as follows: the prepared liquid selects drugs according to the methods of strengthening the body, dispersing nodules, removing dampness and nourishing blood, auxiliary materials of medicinal and edible origin are selected and trace elements containing zinc are added, microbial fermentation engineering and magnetization technology are used to enrich chelated zinc and selenium elements, analyze active peptides and extract traditional Chinese medicine components, etc., to form peptide zinc ion bonds and peptide selenium ion bonds, and the zinc element shows magnetic moment through "magnetizer comprehensive reaction", and the hysteresis effect of ultrasound in the magnetic field and the paramagnetism of free radicals are used to form a highly efficient combined effect of ultrasound, magnetic field, drug zinc and selenium ions. Its characteristics are that the preparation liquid is magnetized by a magnetizer, enters the blood after human diet and injection, and contacts the skin through a coupling agent, so that the ultrasonic magnetic head can form a weak magnetic field with the treatment part of the human body, and target docking with the ultrasonic magnetic field. Through the "ultrasonic magnetic Chinese medicine coupling therapeutic instrument", the human body part is massaged, and under the coupling of ultrasonic waves, magnetic fields and compounds, a hysteresis effect is produced. Under safe conditions, the ultrasonic therapeutic effect can be exerted in the human blood, and the "external massage" can start the "intracellular massage" effect, so that the tissue cytoplasm rolls, the cells vibrate, rotate and rub, and directly act on: (i) regulating the glucose metabolic pathway of immune cells, deepening cell differential imprinting, and improving immune response ability; (ii) anti-oxidation, anti-inflammatory, and scavenging free radicals; (iii) changing the permeability of the cell membrane of tendons, bones and joints, promoting metabolism and enzyme activity, accelerating blood circulation and lymphatic circulation, improving the ischemic and hypoxic state of cells caused by various factors, and improving tendons, bones and joints pain.

[0044] The present invention has the following effects on prostate tissue: (1) increasing blood flow and reducing vascular resistance, improving the concentration, viscosity, aggregation and coagulation of blood, regulating blood coagulation, preventing thrombosis and promoting thrombus dissolution; (2) regulating the body's reactivity to achieve antibacterial and anti-infection effects; (3) affecting the permeability of capillaries, reducing inflammatory exudation, promoting the absorption of inflammatory exudates, inhibiting the formation of inflammatory granulomas, and lysing necrotic tissue at the proliferative site.

[0045] The present invention is feasible for use in preparing medical device drugs and / or health products (health food and special medical food) for anti-oxidation, improving immunity, preventing and treating prostate diseases, and pain in tendons, bones and joints.

[0046] In the description of the present invention, when there are descriptions of words such as up and down, size, etc., unless there are clear limitations, words such as setting, installing, connecting, etc. should be understood in a broad sense, and technical personnel in the relevant field can reasonably determine the specific use of the relevant data in the present invention based on the specific content of the technical solution. BRIEF DESCRIPTION OF THE DRAWINGS

[0047] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0048] Figure 1 It is a schematic diagram of the functional results of the present invention, which comprises an ultrasonic generator (massage head), a magnetic field generator (magnetic head), a magnetizer and a preparation liquid (traditional Chinese medicine tea).

[0049] Figure 2 This is a cross-sectional structural diagram of the "ultrasonic massage head and magnetic head" structure of the present invention, in which (1) is an ultrasonic generator, (2) is a massage head, (3) is the adhesive bonding point between the massage head and the magnetic head, and (4) is the magnetic head of the magnetic field generator; (5) is a channel on the magnetic head, through which the treatment liquid (traditional Chinese medicine tea) can contact the treatment part of the human body and act as a coupling agent.

[0050] Figure 3 This is a partial cross-sectional structural diagram of the "magnetizer" of the present invention, in which (1) is the water inlet, "prepared liquid (traditional Chinese medicine tea)" is introduced from this inlet, water cuts the magnetic lines of force, and flows out after being magnetized, (2) is the water outlet, (3) is the magnet, (4) is the stainless steel (foreskin), and (5) is the stainless steel water pipe. DETAILED DESCRIPTION

[0051] It should be understood that the implementation of the "ultrasonic magnetic Chinese medicine coupling therapeutic apparatus" of the present invention is not limited to the following embodiments, and any form of modification and / or change made to the present invention will fall within the scope of protection of the present invention.

[0052] In the present invention, unless otherwise specified, all relative units of weight parts and volume parts are kilograms and liters, and all equipment and raw materials can be purchased from the market or are commonly used in the industry. The methods in the following embodiments are conventional methods in the art unless otherwise specified.

[0053] Example 1 Preparation of Ultrasonic Magnetic Traditional Chinese Medicine Coupling Therapeutic Instrument

[0054] (I) Equipment and instrument manufacturing

[0055] The ultrasonic generator of the present invention is UT1032 type "ultrasonic physiotherapy instrument" produced by Shenzhen Dongdixin Technology Co., Ltd., with a power supply of 220V and a frequency of 1MHz. The massage head is as shown in the attached Figure 2As shown in (2), the effective radiation area is 4.0 square centimeters, the diameter is 2.4 centimeters, the output power is 4.8W, the effective sound intensity is 0.75-1.2W / square centimeter, and the treatment time can be selected to be 10-15 minutes. Figure 2 The magnetic heads (4) in the apparatus are connected with metal glue and have the same size.

[0056] The magnetic field generator is made of NdFeB strong magnet material, referred to as magnetic head (4), see attached Figure 2 The invention relates to a method for manufacturing a magnetic treatment apparatus, wherein a channel (5) is provided in the middle and lower part, through which the preparation liquid (coupling agent) can contact the treatment part of the human body. The shape is cylindrical disk-shaped. According to the magnetic field strength requirements and material data, the thickness is 1.5 cm, the outer diameter is 4.5 cm, and the axial magnetization (thickness magnetization) is performed. A channel with a diameter of 3 mm is provided on the magnetic head. During treatment, the preparation liquid (traditional Chinese medicine) can contact the treatment part of the human body through this channel, and play the role of coupling agent. The magnetic field strength is 2800-3000GS. The magnetic head (4) is connected to the ultrasonic treatment massage head (2) by metal adhesive bonding (3).

[0057] The magnetizer can be made of "NdFeB strong magnet" material, refer to the attached Figure 3 The invention is manufactured in the shape of a tubular cylindrical vessel, with a length of 60 cm and an outer diameter of 6 cm. A cylindrical magnet (3) is arranged inside the vessel. A hole with a diameter of 2 cm is axially opened in the center and a stainless steel tube (5) is arranged to allow liquid to flow. The magnetic field intensity (radial) is 2600-5000 GS or above. The inner and outer layers of the magnet are wrapped with stainless steel skin (thickness 0.1 cm) (4), which can make the peripheral magnetic field very low (less than 1000 GS) and safe for human body. Each time, 250-400 ml of the preparation liquid (traditional Chinese medicine tea) is put into the water inlet (1). The magnetization flow rate is 2.5 M / S at room temperature and the magnetization time is 5-15 minutes. The liquid is discharged from the water outlet (2).

[0058] (II) Preparation of preparation liquid (Chinese herbal tea)

[0059] Recipe (portions in grams):

[0060]

[0061] The preparation method comprises the following steps:

[0062] (1) weighing the raw materials "lingzhi, ginseng, oyster, kelp, coix seed, dandelion, angelica, tuckahoe, chicory, malt, magnetite, Brazil nut" according to the above formula ratio, mixing, slicing, adding 3 times the amount of water, soaking for 3 hours, then steaming for 30-45 minutes, cooking and storing;

[0063] (2) inoculating the above-mentioned matured material with yeast strains and stirring for fermentation, with the inoculation ratio of 1-1.5% by weight, the pH value being 6-8, the temperature being 20-31° C., and the fermentation process being carried out for 1.5-2 hours;

[0064] (3) adding enzymes, protease (0.1%) and lipase (0.1%) to the fermentation liquid, performing enzymolysis for 4-6 hours at a temperature of 50-61° C., a pH of 5-7.5 and stirring, analyzing the polypeptides, inactivating the enzymes, filtering and concentrating to obtain a “polypeptide liquid”;

[0065] (4) The fermented drug residue is boiled again with water, the first time for 35-45 minutes, and the second time for 0.5-1.0 hour, the decoction is combined, mixed with the above-mentioned polypeptide drug solution, finely filtered, concentrated, and the drug solution is collected to obtain "water-extracted fermented peptide drug solution";

[0066] (5) The fermented medicinal residue is subjected to conventional Ganoderma lucidum fermentation and culture method to produce Ganoderma lucidum-containing substances.

[0067] (6) boiling the Ganoderma lucidum fungus with water for 35 minutes for the first time and 45 minutes for the second time, combining the decoctions, filtering and concentrating, collecting the medicinal liquid, and obtaining the "Ganoderma lucidum medicinal liquid";

[0068] (7) adding enzymes, protease (0.1%) and lipase (0.1%) to the above-mentioned Ganoderma lucidum medicinal liquid, performing enzymolysis for 4-6 hours at a temperature of 50-61° C., a pH of 5-7.5 and stirring to parse out the polypeptides, inactivate the enzymes, filter and concentrate to obtain “Ganoderma lucidum peptide medicinal liquid”;

[0069] (8) The above-mentioned "water-extracted fermented peptide liquid" and "Ganoderma lucidum peptide liquid" are mixed with zinc powder weighed according to the above-mentioned proportion, stirred and mixed for chelation to form a peptide-zinc chelate, filtered and purified, and filled to obtain the "ultrasonic magnetic Chinese medicine coupling therapeutic device" preparation liquid (Chinese medicine tea).

[0070] The concentration of the prepared liquid (Chinese medicinal tea) of the present invention is 1:2 with dry medicinal materials to liquid (medicine), and each milliliter is equivalent to 0.5 grams of raw medicinal materials. According to laboratory tests, the main functional indicators are: polypeptide content ≥ 10%, saponin content 50mg / 100ml, selenium content 50 micrograms / 100ml, zinc content 60mg / 100ml, and daily dosage 6ml / kg body weight. The part used as coupling agent can be prepared with high-quality liquor to be 30-70% VOL.

[0071] Example 2 Immunity enhancement and safety test

[0072] The prepared liquid (Chinese herbal tea) of the present invention passed the acute toxicity test (median lethal dose and maximum tolerated dose) in mice. The test results show that the median lethal dose of the Chinese herbal tea is 20 g / kg·BW, and the maximum tolerated dose is 160 g / kg·BW. The test proves that the Chinese herbal tea is safe.

[0073] The "ultrasonic magnetic Chinese medicine coupling therapeutic instrument" of the present invention can improve immunity. The mouse immunosuppression pathological model was artificially reproduced by cyclophosphamide, and two experiments were conducted on healthy mice and immunosuppressed mice respectively. Each experiment was divided into three different concentration treatment groups of 6ml / kg, 4ml / kg and 2ml / kg and a control group. The Chinese medicine tea was magnetized, and each mouse was gavaged with the required amount according to body weight / d. The control group was gavaged with an equal amount of distilled water, and physical therapy and massage treatment were carried out for 15 minutes / d. Physical therapy was continuously gavaged for 14 days, and hematological indicators (red blood cells, white blood cells, hemoglobin content, hematocrit, neutrophils, lymphocytes, eosinophils and basophils), spleen organ index and body weight gain were detected. The relationship between the concentration of the Chinese medicine tea of ​​the present invention, physical therapy time and effect was studied, and the effect of the present invention on T lymphocyte subsets, B lymphocyte serum hemolysin (IgM) and peritoneal macrophage phagocytosis of mice in the healthy group and the immunosuppressed group was detected. In two tests of the present invention on healthy mice and immunosuppressed mice, the hematological indexes, spleen organ index and body weight gain of the present invention group were improved compared with the control group, and the concentration-effect was positively correlated. In the test of the present invention on healthy mice, the CD4~+ / CD8~+ value of the present invention group was not significantly different from that of the control group (P>0.05), the IgM value and phagocytosis percentage were significantly different (P>0.05), and the phagocytosis index was extremely significantly different (P>0.01). In the test of the present invention on immunosuppressed mice, the CD4~+ / CD8~+, IgM, phagocytosis rate and phagocytosis index of the present invention group were extremely significantly different from that of the control group (P<0.01).

[0074] Example 3 Preliminary clinical trial for the treatment of prostate disease

[0075] In order to observe the curative effect of the present invention in treating prostate diseases, 50 patients with benign prostatic hyperplasia were selected for clinical verification. Results: 11 cases were clinically cured, 23 cases were markedly effective, 14 cases were effective, 2 cases were ineffective, and the total effective rate was 96%. Conclusion: The massage treatment of benign prostatic hyperplasia by the present invention has significant curative effect and has a positive effect on the prevention and treatment of prostate diseases.

[0076] Benign prostatic hyperplasia (also known as prostatic hypertrophy) is one of the most common and difficult diseases of the urinary system in men over 55 years old. It belongs to the category of "urinary retention" and "stranguria" in traditional Chinese medicine. Clinically, it often manifests as frequent urination at night, dysuria, and even acute urinary retention and urinary incontinence, which seriously affects the quality of life of patients. Conservative treatment is currently the best treatment method.

[0077] 1 Patient general information

[0078] All 50 patients were outpatients, with the youngest being 55 years old and the oldest being 70 years old. The shortest course of disease was 1 year and the longest was 10 years. Patients with concomitant stones and renal insufficiency were excluded.

[0079] 2 Diagnostic criteria

[0080] 2.1 Western medicine diagnostic criteria

[0081] Dysuria: waiting to urinate, time-consuming and laborious, thin urine stream, incomplete urine, and incontinence in severe cases. Anal examination: enlargement of both lobes of the prostate, medium hardness, shallow or disappearance of the central groove. Ultrasound examination: uniform enlargement of the prostate, increased residual urine.

[0082] 2.2 Standards for TCM Syndrome Differentiation

[0083] Dripping urination, weak urination, lower abdominal distension, increased nocturia, incomplete urination, soreness of the waist and knees, or fear of cold and cold limbs, pale tongue, or blood stasis, and a thready and weak pulse.

[0084] 3 Treatment methods

[0085] Pour the prepared liquid (Chinese herbal tea) into the magnetizer at 6ml / kg body weight for magnetization. A portion is reserved as a coupling agent, a portion is directly taken orally, and a portion is injected into the prostate. After 30-45 minutes of "oral" magnetized Chinese herbal tea, use the ultrasonic magnetic head to massage the patient's prostate (the magnetic head has the prepared liquid as a coupling agent). The massage treatment lasts for 30 minutes. 3 times a day, for 20 consecutive days.

[0086] 4 Results

[0087] 4.1 Efficacy criteria

[0088] According to relevant national regulations, clinical cure: symptoms disappear and the size of the prostate is normal after B-ultrasound examination; marked effect: symptoms are significantly alleviated and the size of the prostate is close to normal after B-ultrasound examination; improvement: symptoms improve and the prostate is smaller than before after B-ultrasound examination; ineffective: there is no obvious change in symptoms and B-ultrasound examination compared with before treatment.

[0089] 4.2 Treatment outcomes

[0090] 11 cases (22%) were clinically cured, 23 cases (46%) were markedly effective, 14 cases (28%) were effective, 2 cases (4%) were ineffective, and the total effective rate was 96%.

[0091] Example 4 Animal test on relieving joint swelling and pain in rats

[0092] (I) Test materials:

[0093] (1) Animals: 40 rats (Qingdao, Shandong Province), half male and half female, weighing 500 g ± 1 g, were randomly divided into four groups: A, B, C, and D, with 10 rats in each group.

[0094] (2) The "prepared liquid (Chinese medicinal tea)" of the present invention is produced according to the method of the above-mentioned "Specific Implementation Example 1".

[0095] (3) The treatment system facility of the present invention is prepared according to the method of Example 1.

[0096] (II) Rat breeding conditions:

[0097] The temperature during feeding is required to be between 20-25°C and the humidity is between 50-65%. During the whole test process, the rats are free to eat and drink, and the environment is well ventilated and clean.

[0098] (III) Treatment methods:

[0099] (1) Establishment of acute gout model: The model was established by the classical modeling method. An injection needle was inserted into the inner side of the tibial tendon at a 45° angle on the dorsal side of the right ankle joint of all rats in groups B, C, and D, and 0.25 mL of sodium urate solution (concentration 2.4 g.100 mL-1) was injected into the ankle joint cavity to form an experimental gouty arthritis model. Group A was not treated with an acute gout model.

[0100] (2) Group A: As the control group, no treatment was given.

[0101] (3) Group B: Magnetized drinking water plus physical therapy with "ultrasonic magnetic Chinese medicine coupling therapeutic device". Each time, the drinking water was magnetized for 15 minutes before oral administration, followed by physical therapy for 15 minutes 30 minutes later, 3 times a day, with a daily dosage of 6 ml / kg body weight, for one week.

[0102] (4) Group C: Magnetization and oral treatment with "prepared liquid (Chinese herbal tea)" alone. Magnetization lasts 15 minutes each time, and the drug is taken orally 3 times a day, with a daily dosage of 6 ml / kg body weight, for one week.

[0103] (5) Group D: The therapeutic apparatus of the present invention was used, and the preparation liquid (Chinese herbal tea) was added for oral administration, with a daily dosage of 6 ml / kg body weight. The preparation liquid was magnetized for 15 minutes before drinking, and massage treatment was performed 30 minutes later, 3 times a day, each time for 15 minutes, for one week.

[0104] (IV) Observation indicators and evaluation methods: The observation indicators include the mental state, overall health, diet, circumference, swelling, color, skin temperature and activity of the same part of the right ankle joint of the rats, and calculate the degree of joint swelling. Calculation of joint swelling: Use a vernier caliper to measure the average circumference of the same part of the right ankle joint of each group of rats before the experiment and 3, 6, 12, 24, 48, 72 and 120 hours after modeling, and calculate the difference in the circumference of the right ankle joint before and after modeling.

[0105] (V) Results

[0106] (1) The rats in group A of the control group showed no obvious signs of irritability. Their joints were slightly thicker than before modeling, but remained basically unchanged. There was no obvious redness, heat, or functional impairment.

[0107] (2) After the inflammation model was established in the rats of groups B, C and D, the rats were obviously restless, with obvious redness, swelling and heat in the right ankle joint, accompanied by functional impairment and limited movement. After the treatment with the above method, the rats in group B were relatively restless, the rats in group C were a little restless, and the rats in group D were obviously restless, indicating that the therapeutic apparatus of the present invention has the effect of relieving pain and can be used in medicines and medical devices for muscle, bone and joint pain.

[0108] The preferred specific implementation modes and embodiments of the "ultrasonic magnetic Chinese medicine coupling therapeutic device" of the present invention are described in detail above, but the present invention is not limited to the above implementation modes and embodiments. Various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the concept of the present invention.

Claims

1. An ultrasonic magnetic Chinese medicine coupling therapeutic instrument, consisting of an ultrasonic generator, a magnetic field generator, a magnetizer, and a preparation liquid (Chinese medicine tea), characterized in that: A magnetic field transmitter (magnetic head) is arranged and connected in the shell of the ultrasonic generator massage head. During massage treatment, the person first drinks the preparation liquid (Chinese herbal tea) magnetized by the magnetizer, and the massage magnetic head contacts the preparation liquid and the human body parts, producing a comprehensive therapeutic effect.

2. The ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to claim 1, characterized in that: The magnetic field generator (magnetic head) is made of magnetic material and is cylindrical in shape. A channel is opened in the middle and lower part. The preparation liquid (Chinese herbal tea) can contact and couple with the treatment part of the human body through this channel. It is axially magnetized, and its area is consistent with the area of ​​the ultrasonic head. The thickness is determined by the magnetic field strength data. The magnetic head is connected to the ultrasonic massage head.

3. The ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to claim 1 or 2, characterized in that: The "magnetizer" is made of magnets and stainless steel materials. It is shaped like a tubular cylindrical vessel with a cylindrical magnet inside. An axial hole in the center is used to install a stainless steel tube to allow liquid to flow. The magnetic field strength (radial) is 2600-5000GS. The outer circumference is wrapped with stainless steel leather. During treatment, the accompanying liquid (traditional Chinese medicine tea, drinking water, oral liquid) can be poured into it and flow out after being magnetized for use during treatment.

4. The ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to claims 1-3, characterized in that: The prepared liquid (Chinese medicinal tea) is made from the following raw materials in the following weight ratio:

5. The ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to claims 1-4, characterized in that: The preparation method of the prepared liquid (Chinese medicinal tea) comprises the following steps: (1) weighing the raw materials "lingzhi, ginseng, oyster, kelp, coix seed, dandelion, angelica, tuckahoe, chicory, malt, magnetite, Brazil nut" according to the above formula ratio, mixing, slicing, steaming, cooking, and storing; (2) inoculating the above-mentioned matured material with yeast strains and stirring and then fermenting; (3) adding the fermentation liquid to the enzyme for enzymolysis to separate the polypeptides, inactivating the enzyme, filtering and concentrating to obtain the polypeptide liquid; (4) The fermented drug residue is boiled with water, the decoction is combined, mixed with the above-mentioned polypeptide drug solution, filtered, concentrated, and the drug solution is collected to obtain "water-extracted fermented peptide drug solution"; (5) The fermented medicinal residue is subjected to conventional Ganoderma lucidum fermentation and culture method to produce Ganoderma lucidum-containing substances. (6) boiling the Ganoderma lucidum-containing fungus with water, combining the decoctions, filtering and concentrating, collecting the medicinal liquid, and obtaining the "Ganoderma lucidum medicinal liquid"; (7) adding an enzyme to the above-mentioned Ganoderma lucidum medicinal liquid to perform enzymolysis to parse out the peptides, inactivate the enzyme, filter, and concentrate to obtain "Ganoderma lucidum peptide medicinal liquid"; (8) The above-mentioned "water-extracted fermented peptide liquid" and "Ganoderma lucidum peptide liquid" are mixed with zinc powder weighed according to the above-mentioned proportion, stirred and mixed for chelation to form a peptide zinc chelate, filtered and purified, and filled to obtain the "ultrasonic magnetic Chinese medicine coupling therapeutic device" preparation liquid (Chinese medicine tea).

6. Use of the ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to any one of claims 4 to 5 in the preparation of health food (tea) for improving immunity.

7. Use of the ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to any one of claims 1 to 5 in the preparation of medical devices for treating muscle, bone and joint pain.

8. Use of the ultrasonic magnetic Chinese medicine coupling therapeutic apparatus according to any one of claims 1 to 5 in the preparation of medical devices for preventing and treating prostate diseases.

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