Implantation device and implantation system

Abstract

The invention discloses an implantation device and an implantation system. The implantation device comprises a shell, a first tube body and an inner core. The housing has a first opening. The first tube body is connected to the shell, at least part of the first tube body extends out of the shell through the first opening, the first tube body is provided with a holding part located outside the shell, and the holding part is configured to keep the sheet implant located at the holding part in a winding state. At least part of the inner core is located in the first tube body, and the inner core is configured to be movably arranged relative to the first tube body in the axial direction of the first tube body and enables the sheet-shaped implant in the winding state to be separated from the maintaining part. Before implantation, the wound state of the sheet-shaped implant is kept through the keeping part, so that the wound can be as small as possible, and the reduction of the operative wound is facilitated. After the implantation device is implanted into the target position, the holding part can release the sheet-shaped implant, so that the sheet-shaped implant is naturally unfolded, other unfolding devices are not needed, and the structure of the implantation device is simplified.

Description

Technical Field

[0001] The present application belongs to the field of medical technology, and in particular relates to an implant device and an implant system. Background Art

[0002] Macular degeneration is a major neurological blinding disease with limited clinical treatment options. Stem cell therapy, however, brings hope to this type of disease because it can differentiate directly to replace degenerated cells or secrete nutritional factors that promote the survival of existing cells to achieve the purpose of treating macular degeneration. Currently, the most widely used cell transplantation method is subretinal cell suspension injection. Although this method can inject a large number of cells at one time, the suspended cells need to rebuild cell polarity and intercellular synapses after injection, which greatly reduces the treatment efficiency. Summary of the invention

[0003] The embodiments of the present application provide an implantation device and an implantation system, which can achieve effective implantation of sheet-like implants through smaller incisions, thereby improving treatment efficiency.

[0004] According to the first aspect of the present application, the present application provides an implant device, which includes: a shell having a first opening; a first tube body connected to the shell, at least a portion of the first tube body extending out of the shell through the first opening, the first tube body having a retaining portion located outside the shell, the retaining portion being configured to retain a sheet-like implant in the retaining portion in a wound state; an inner core, at least a portion of the inner core being located within the first tube body, the inner core being configured to be movably arranged relative to the first tube body along the axial direction of the first tube body, and allowing the sheet-like implant in the wound state to detach from the retaining portion.

[0005] In some embodiments, the inner core has a support portion at one end along the axial direction of the first tube body, and the support portion is capable of supporting the sheet-like implant in a wound state; the support portion has a first state and a second state, in the first state, the retaining portion is located on the radial outside of the support portion along the first tube body, and in the second state, the support portion and the retaining portion are at least partially staggered along the axial direction of the first tube body.

[0006] In some embodiments, the support portion includes two elastic clamp arms, which are separately arranged and radially opposite to each other along the first tube body, and the two elastic clamp arms are configured to elastically deform in directions approaching and / or moving away from each other; in a first state, the two elastic clamp arms are closed and can clamp the sheet-like implant; in a second state, the two elastic clamp arms are open and can release the sheet-like implant.

[0007] In some embodiments, the implant device also includes a second tube body, which is inserted into the first tube body, and at least a portion of the inner core is inserted into the second tube body. The inner core is configured to be movably arranged relative to the second tube body along the axial direction of the first tube body to close the two elastic clamp arms through the second tube body.

[0008] In some embodiments, the first tube body includes a main tube, a portion of which extends out of the shell; and the retaining portion is connected to an end of the main tube located outside the shell.

[0009] In some embodiments, the retaining portion is a tubular structure, and a receiving cavity is defined inside the retaining portion, and the receiving cavity can receive the sheet-like implant in a rolled state.

[0010] In some embodiments, the retaining portion is detachably connected to the main body; the inner core is used to push the sheet-like implant in a rolled state in the retaining portion out of the retaining portion.

[0011] In some embodiments, the retaining portion is fixedly sleeved on the outer side of the end of the main pipe, and the inner diameter of the retaining portion is greater than the inner diameter of the main pipe.

[0012] In some embodiments, the retaining portion includes at least one limiting strip extending from an end of the main tube along the axial direction of the main tube toward a direction away from the main tube, and the limiting strip protrudes from an outer tube wall of the main tube along the radial direction of the main tube.

[0013] In some embodiments, the implant device further comprises a driving mechanism, which is connected to the inner core and / or the first tube body and is used to drive the inner core and / or the first tube body to move along the axial direction of the first tube body.

[0014] In some embodiments, the shell includes two second openings, which are arranged opposite to each other along the radial direction of the first tube body; the driving mechanism includes a first sub-driving mechanism, which includes two elastic arms, which are arranged opposite to each other along the radial direction of the first tube body, and each elastic arm protrudes and bends outward along the radial direction of the first tube body, and the bent parts of the two elastic arms are respectively exposed to the outside of the shell through the two second openings; one end of the elastic arm is connected to the shell, and the other end is connected to the inner core.

[0015] In some embodiments, the driving mechanism includes a second sub-driving mechanism, which includes a sliding member arranged on the shell, and the sliding member is configured to be movably arranged relative to the shell along the axial direction of the first tube body; one axial end of the first tube body is fixedly connected to the sliding member.

[0016] In some embodiments, a sliding groove is provided in the shell, the sliding groove extends along the axial direction of the first tube body, and a portion of the sliding member is provided in the sliding groove; the shell is provided with a third opening, the third opening connects the inside and the outside of the shell, and a portion of the sliding member is exposed to the outside of the shell through the third opening.

[0017] According to the second aspect of the present application, an embodiment of the present application also provides an implantation system, which includes: an implantation device provided according to any embodiment of the present application; and a sheet-like implant configured to be rollable, and the sheet-like implant can be detachably arranged in a retaining portion of the implantation device.

[0018] The implant device provided in the embodiment of the present application includes a shell, a first tube body and an inner core. The first tube body has a retaining portion located outside the shell, and the retaining portion can retain the sheet-like implant in the retaining portion in a coiled state. At least part of the inner core is located in the first tube body, and the inner core can move axially relative to the first tube body so that the sheet-like implant in the coiled state can be separated from the retaining portion. Before implantation, the sheet-like implant can be rolled into a coiled state and placed in the retaining portion. During the implantation process, the sheet-like implant remains in a coiled state and does not unfold under the action of the retaining portion. After the implant device implants the sheet-like implant into the target position, the sheet-like implant is separated from the retaining portion through the inner core, and the sheet-like implant can be exposed to the target position and unfolded after swelling by absorbing water, thereby achieving effective implantation of the sheet-like implant.

[0019] The embodiment of the present application effectively utilizes the characteristics of the sheet-like implant that it is easy to roll up in a dry state and to swell and stretch when exposed to water. The sheet-like implant is kept in a rolled state by a retaining portion before implantation, which can minimize the size of the head of the implant device, thereby making the incision as small as possible, which is beneficial to reducing surgical trauma. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments of the present application will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0021] Figure 1 It is a schematic diagram of the structure of the implant device provided in some embodiments of the present application.

[0022] Figure 2 yes Figure 1 A schematic cross-sectional view of the implant device shown.

[0023] Figure 3 yes Figure 2 Schematic diagram of the enlarged structure of area A in the middle.

[0024] Figure 4 yes Figure 1 A partial cross-sectional schematic diagram of the implant device in another state is shown.

[0025] Figure 5 yes Figure 4 Schematic diagram of the enlarged structure of area B in the middle.

[0026] Figure 6 It is a schematic diagram of partial structural decomposition of an implant device provided according to other embodiments of the present application.

[0027] Figures 7a to 7cIt is a partial structural schematic diagram of an implant device in different states provided according to some embodiments of the present application.

[0028] In the attached figure:

[0029] Implant device 100, sheet-shaped implant 200;

[0030] Shell 10, first shell part 10a, second shell part 10b, first opening 11, slot 12, sliding wall 15, second opening 19, sliding slot 17, third opening 18, first tube body 20, retaining part 21, accommodating cavity 211, limiting strip 212, main tube 22, inner core 30, supporting part 311, elastic clamping arm 3111, main body 312, second tube body 40, sliding member 61, first sub-driving mechanism 70, elastic arm 71, connecting part 72, sliding part 73. DETAILED DESCRIPTION

[0031] In order to make the purpose, technical solution and advantages of the embodiments of the present application clearer, the technical solution in the embodiments of the present application will be clearly described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0032] Unless otherwise defined, all technical and scientific terms used in this application have the same meanings as those commonly understood by technicians in the technical field of this application; the terms used in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application; the terms "including" and "having" in the specification and claims of this application and the above-mentioned drawings and any variations thereof are intended to cover non-exclusive inclusions. The terms "first", "second", etc. in the specification and claims of this application or the above-mentioned drawings are used to distinguish different objects, rather than to describe a specific order or a primary and secondary relationship.

[0033] Reference to "embodiment" in this application means that a particular feature, structure, or characteristic described in conjunction with the embodiment may be included in at least one embodiment of the present application. The appearance of the phrase in various places in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments.

[0034] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", and "attached" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0035] The term "and / or" in this application is only a description of the association relationship of associated objects, indicating that there can be three relationships. For example, A and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. In addition, the character " / " in this application generally indicates that the associated objects before and after are in an "or" relationship.

[0036] In the embodiments of the present application, the same reference numerals represent the same components, and for the sake of brevity, detailed descriptions of the same components are omitted in different embodiments. It should be understood that the thickness, length, width and other dimensions of various components in the embodiments of the present application shown in the drawings, as well as the overall thickness, length, width and other dimensions of the integrated device are only exemplary descriptions and should not constitute any limitation to the present application.

[0037] The term "plurality" used in the present application refers to two or more (including two).

[0038] In the embodiments of the present application, "parallel" includes not only the absolutely parallel situation, but also the roughly parallel situation conventionally recognized in engineering; at the same time, "vertical" includes not only the absolutely vertical situation, but also the roughly vertical situation conventionally recognized in engineering.

[0039] Stem cell therapy is one of the effective ways to treat macular degeneration. The applicant found that although the subretinal cell suspension injection method can inject a large number of cells, the suspended cells need to rebuild cell polarity and intercellular synapses after injection, which greatly reduces the treatment efficiency. Therefore, it is necessary to seek a new treatment plan.

[0040] The transplantation of cell implants has a higher success rate than that of cell suspensions. However, cell implants are sheet-like structures, and existing implantation devices cannot fully implement the implantation of sheet-like implants.

[0041] The applicant further recognized that a sheet-like implant in a relatively dry state will expand after absorbing water, and a dry sheet-like implant in a rolled state will naturally expand and restore its sheet shape after absorbing water and expanding.

[0042] In view of this, an embodiment of the present application provides a technical solution, which has a shell, a first tube body and an inner core. The first tube body has a retaining portion located outside the shell, and the retaining portion can keep the sheet-like implant in the retaining portion in a coiled state. At least part of the inner core is located in the first tube body, and the inner core can move axially relative to the first tube body so that the sheet-like implant in the coiled state can be separated from the retaining portion. Before implantation, the sheet-like implant can be rolled into a coiled state and placed in the retaining portion. During the implantation process, the sheet-like implant remains in a coiled state under the action of the retaining portion and does not unfold, which can minimize the size of the implantation device head, thereby making the wound as small as possible, which is conducive to reducing surgical trauma. After the implantation device implants the sheet-like implant into the target position, the sheet-like implant is separated from the retaining portion through the inner core, and the sheet-like implant can be exposed to the target position and unfolded after absorbing water and swelling, thereby achieving effective implantation of the sheet-like implant.

[0043] The technical solution provided in the embodiments of the present application is applicable to various implant devices and implant systems, and the implant devices include but are not limited to eye detection devices.

[0044] Figure 1 is a schematic diagram of the structure of an implant device provided in some embodiments of the present application, Figure 2 yes Figure 1 A schematic cross-sectional view of the implant device shown, Figure 3 yes Figure 2 Schematic diagram of the enlarged structure of area A in the middle. Figure 4 yes Figure 1 A partial cross-sectional schematic diagram of another state of the implant device shown, Figure 5 yes Figure 4 Schematic diagram of the enlarged structure of area B in the middle. For ease of understanding, Figure 5 Also shown is a sheet-like implant 200.

[0045] Reference Figures 1 to 5 The implantation device 100 provided in the embodiment of the present application is used to implant a sheet-shaped implant 200. The sheet-shaped implant 200 may be, for example, a cell implant.

[0046] The implant device 100 includes a housing 10, a first tubular body 20 and an inner core 30. The housing 10 has a first opening 11. The first tubular body 20 is connected to the housing 10, and at least a portion of the first tubular body 20 extends out of the housing 10 through the first opening 11. The first tubular body 20 has a retaining portion 21 located outside the housing 10, and the retaining portion 21 is configured to retain a sheet-like implant 200 in the retaining portion 21 in a wound state. At least a portion of the inner core 30 is located in the first tubular body 20, and the inner core 30 is configured to be movably arranged relative to the first tubular body 20 along the axial direction of the first tubular body 20, and to allow the sheet-like implant 200 in the wound state to be separated from the retaining portion 21.

[0047] The housing 10 may include a first housing portion 10 a and a second housing portion 10 b , and the first housing portion 10 a and the second housing portion 10 b are detachably connected so as to install or replace the first tube 20 , the inner core 30 or other components on the housing 10 .

[0048] Optionally, the first housing portion 10a and the second housing portion 10b may be detachably connected by snap connection, screw connection or any other suitable manner.

[0049] The first opening 11 is located at one end of the housing 10 along the axial direction of the first tube 20. The first opening 11 may be provided in one of the first housing portion 10a and the second housing portion 10b, or may be defined by the first housing portion 10a and the second housing portion 10b.

[0050] At least a portion of the first tube 20 is located outside the housing 10 , so that at least a portion of the first tube 20 can extend into the target implantation position.

[0051] One end of the first tube body 20 may be located inside the housing 10, and the other end may be located outside the housing 10. The holding portion 21 may be formed at the end of the first tube body 20 located outside the housing 10.

[0052] The holding portion 21 has the ability to hold the rolled state of the sheet-shaped implant 200. Optionally, the holding portion 21 can hold the rolled state of the sheet-shaped implant 200 by applying radial restraint, pressing, and the like to the sheet-shaped implant 200.

[0053] In one example, the retaining portion 21 may be an annular structure, which can apply a radial restraining effect to the sheet-like implant 200 to limit the expansion of the sheet-like implant 200. For example, the retaining portion 21 may be a limiting tube, a limiting ring, or the like.

[0054] In another example, the retaining portion 21 may be a strip or block structure, which can radially press against the sheet-like implant 200 to limit the expansion of the sheet-like implant 200. For example, the retaining portion 21 may be a pressing strip, a pressing block, or the like.

[0055] In another example, the holding portion 21 may also be a clamping structure, which can clamp the sheet-shaped implant 200 in a rolled state, thereby limiting the unfolding of the sheet-shaped implant 200. For example, the holding portion 21 may be a clamp.

[0056] In one example, the first tube body 20 is fixed relative to the housing 10 , and the inner core 30 is movably disposed relative to the first tube body 20 and the housing 10 along the axial direction of the first tube body 20 .

[0057] In another example, the inner core 30 is fixed relative to the shell 10 , and the first tube 20 is movably disposed along its own axial direction relative to the inner core 30 and the shell 10 .

[0058] In another example, both the first tube body 20 and the inner core 30 are movably disposed relative to the housing 10 along the axial direction of the first tube body 20 , and the movements of the first tube body 20 and the inner core 30 are independent of each other.

[0059] When the inner core 30 moves axially relative to the first tube body 20, the sheet-like implant 200 can be driven to move axially relative to the first tube body 20, so that the sheet-like implant 200 can be separated from the retaining portion 21. There are many ways for the inner core 30 to drive the sheet-like implant 200 to move. For example, the inner core 30 can axially abut against the sheet-like implant 200 to push the sheet-like implant 200; for another example, the sheet-like implant 200 can be supported on the inner core 30 by clamping, winding, etc., and the inner core 30 can drive the sheet-like implant 200 to move synchronously.

[0060] The sheet-like implant 200 detaches from the holding part 21 means that the sheet-like implant 200 leaves the position corresponding to the holding part 21 , the sheet-like implant 200 and the holding part 21 are separated, and the holding part 21 releases the sheet-like implant 200 to release the shape-holding effect on the sheet-like implant 200 .

[0061] Before implantation, the sheet implant 200 can be rolled into a coiled state and placed on the holding portion 21. During the implantation process, the sheet implant 200 is kept in a coiled state and not unfolded under the action of the holding portion 21, which can minimize the size of the head of the implantation device 100, thereby making the implantation wound as small as possible, which is conducive to reducing surgical trauma. After the implantation device 100 implants the sheet implant 200 into the target position, the sheet implant 200 is separated from the holding portion 21 through the inner core 30, and the sheet implant 200 can be exposed to the target position and unfolded after absorbing water and swelling, thereby achieving effective implantation of the sheet implant 200.

[0062] The embodiment of the present application effectively utilizes the characteristics of the sheet implant 200 that it is easy to roll up in a dry state and easy to swell and stretch when exposed to water. The sheet implant 200 is kept in a rolled state by the holding portion 21 before implantation, so that the wound can be as small as possible, which is conducive to reducing surgical trauma. After implantation at the target position, the holding portion 21 releases the sheet implant 200, and the sheet implant 200 can naturally stretch and expand after absorbing water and swelling, without the need for other unfolding devices, which is conducive to simplifying the structure of the implant device 100.

[0063] In some embodiments, the inner core 30 has a support portion 311 at one end along the axial direction of the first tube 20, and the support portion 311 can support the sheet-shaped implant 200 in a rolled state. The support portion 311 has a first state and a second state. In the first state (refer to Figure 5 ), the holding portion 21 is located outside the support portion 311 along the radial direction of the first tube body 20, and in the second state (reference Figure 3), the supporting portion 311 and the retaining portion 21 are at least partially staggered along the axial direction of the first tube body 20.

[0064] The sheet-shaped implant 200 can be supported on the support portion 311 by clamping, winding, etc., and the support portion 311 can drive the sheet-shaped implant 200 to move synchronously along the axial direction of the first tube body 20 .

[0065] The support portion 311 can move axially relative to the first tube body 20 to change the relative position between the support portion 311 and the first tube body 20. In the first state and the second state, the position of the support portion 311 relative to the first tube body 20 is different, and the position relative to the holding portion 21 is also different.

[0066] In the first state, the retaining portion 21 is located on the radially outer side of the supporting portion 311 of the first tube body 20 , and the retaining portion 21 can exert a radial restriction on the sheet-like implant 200 supported by the supporting portion 311 toward the central axis direction of the first tube body 20 to maintain the winding state of the sheet-like implant 200 .

[0067] In the second state, the support portion 311 and the retaining portion 21 are at least partially offset along the axial direction of the first tube body 20, the sheet-like implant 200 supported by the support portion 311 can be separated from the retaining portion 21, and the restrictive effect of the retaining portion 21 on the sheet-like implant 200 is released, which is conducive to the unfolding of the sheet-like implant 200.

[0068] At least in the second state, the support portion 311 is located outside the housing 10 so as to be staggered with the holding portion 21, so that the holding portion 21 releases the sheet-like implant supported by the support portion 311. In the first state, the support portion 311 can be located outside the housing 10 or inside the housing 10.

[0069] The embodiment of the present application provides a support portion 311, which can support the sheet-like implant 200 in a wound state, and enable the sheet-like implant 200 to move axially relative to the first tube body 20 together with the support portion 311, thereby changing the position of the sheet-like implant 200 relative to the retaining portion 21, and realizing the retention and release of the wound state of the sheet-like implant 200 by the retaining portion 21 with a simple structure.

[0070] In some embodiments, the support portion 311 includes two elastic clamp arms 3111, which are separately disposed and face each other along the radial direction of the first tube 20, and the two elastic clamp arms 3111 are configured to elastically deform in a direction of approaching and / or moving away from each other. In a first state, the two elastic clamp arms 3111 are closed and can clamp the sheet-like implant 200; in a second state, the two elastic clamp arms 3111 are open and can release the sheet-like implant 200.

[0071] In the second state, the two elastic clamp arms 3111 are open, that is, in a state of being away from each other, and a jaw is formed between the two elastic clamp arms 3111. The sheet-like implant 200 can be inserted into the jaw before winding the sheet-like implant 200. Afterwards, the support portion 311 can be switched to the first state by the axial relative movement between the inner core 30 and the first tube body 20. During the switching process, the support portion 311 gradually moves toward the inside of the first tube body 20 or other tube bodies, and the first tube body 20 or other tube bodies exerts an extrusion effect on the two elastic clamp arms 3111, causing the two elastic clamp arms 3111 to deform in a direction of approaching each other until the jaw between the two elastic clamp arms 3111 disappears, and the sheet-like implant 200 is clamped between the two elastic clamp arms 3111 and is not easy to fall off.

[0072] It is understandable that in the second state, the two elastic clamp arms 3111 can be in a natural state; in the first state, the two elastic clamp arms 3111 always have a tendency to deform in a direction away from each other. After the support portion 311 switches from the first state to the second state, the two elastic clamp arms 3111 can automatically unfold under the action of the elastic deformation restoring force.

[0073] After the two elastic clamping arms 3111 clamp the sheet-shaped implant 200 , the two elastic clamping arms 3111 can form a support shaft, and the sheet-shaped implant 200 can be wrapped around the outside of the two elastic clamping arms 3111 .

[0074] After the sheet-like implant 200 is implanted to the target position, the support portion 311 may be switched to the second state to release the clamping effect on the sheet-like implant 200 and reduce the interaction force between the support portion 311 and the sheet-like implant 200 .

[0075] The embodiment of the present application is provided with two elastic clamping arms 3111, and the sheet-like implant 200 is clamped or released by the elastic deformation of the two elastic clamping arms 3111, which is conducive to improving the support stability and reliability of the support part 311 on the sheet-like implant 200. In addition, the implant device 100 can be withdrawn after the support part 311 releases the sheet-like implant 200, which is conducive to reducing the influence on the position of the sheet-like implant 200 and improving the accuracy of the implantation position of the sheet-like implant 200.

[0076] In some embodiments, the implant device 100 also includes a second tube body 40, which is inserted into the first tube body 20, and at least a portion of the inner core 30 is inserted into the second tube body 40. The inner core 30 is configured to be movably arranged relative to the second tube body 40 along the axial direction of the first tube body 20 so as to close the two elastic clamp arms 3111 through the second tube body 40.

[0077] In the first state, a portion of the elastic clamp arm 3111 is located in the second tube body 40, so that the two elastic clamp arms 3111 are limited by the second tube body 40; in the second state, the elastic clamp arm 3111 may extend out of the second tube body 40 as a whole or partially. It can be understood that in the first state, the length of the elastic clamp arm 3111 in the second tube body 40 is greater than the length of the elastic clamp arm 3111 in the second tube body 40 in the second state.

[0078] Optionally, the second tube body 40 is fixed relative to the housing 10, and the inner core 30 is movably arranged relative to the second tube body 40 and the housing 10 along the axial direction of the first tube body 20. The first tube body 20 is movably arranged relative to the second tube body 40 and the housing 10 along its own axial direction. The movement of the inner core 30 and the first tube body 20 is independent of each other.

[0079] Exemplarily, a slot 12 may be provided in the housing 10 , one end of the second tube 40 is snapped into the slot 12 , and the other end extends out of the housing 10 .

[0080] Alternatively, the inner core 30 may also be fixed relative to the shell 10 , and the second tube 40 may be movably disposed relative to the inner core 30 and the shell 10 along the axial direction of the first tube 20 .

[0081] In the first state, the portion of the elastic clamp arm 3111 that does not clamp the sheet-shaped implant 200 is located inside the second tube body 40 , and the portion of the elastic clamp arm 3111 that clamps the sheet-shaped implant 200 is located outside the second tube body 40 .

[0082] When the two elastic clamp arms 3111 move axially toward the inside of the second tube body 40, the second tube body 40 exerts a pressing force on the two elastic clamp arms 3111, causing the two elastic clamp arms 3111 to elastically deform toward each other, thereby clamping the sheet-like implant 200. When the two elastic clamp arms 3111 move axially toward the outside of the second tube body 40, the restrictive effect of the second tube body 40 on the elastic clamp arms 3111 is gradually released, and the two elastic clamp arms 3111 recover their deformation toward the direction of moving away from each other, thereby releasing the sheet-like implant 200.

[0083] The embodiment of the present application selectively clamps or releases the sheet-like implant 200 by providing the second tube body 40 and adjusting the state of the two elastic clamp arms 3111 through the axial relative movement between the second tube body 40 and the inner core 30. The embodiment of the present application also adjusts the relative position between the retaining portion 21 and the two elastic clamp arms 3111 through the axial relative movement between the first tube body 20 and the inner core 30, thereby maintaining or releasing the winding state of the sheet-like implant 200. The axial relative movement between the second tube body 40 and the inner core 30 and the axial relative movement between the first tube body 20 and the inner core 30 are independent of each other and do not affect each other, which is conducive to more stably supporting the sheet-like implant 200 and more stably maintaining the winding state of the sheet-like implant 200.

[0084] The second tube body 40 is inserted into the first tube body 20 , and the inner diameter of the second tube body 40 is smaller than the inner diameter of the first tube body 20 , which is helpful to reduce the shaking of the inner core 30 during the axial movement process.

[0085] In other embodiments, the support portion 311 may also be a support shaft, and the sheet implant 200 may be directly wrapped around the support shaft using tweezers or other tools, thereby eliminating the second tube 40 , which helps to simplify the structure of the implant device 100 .

[0086] In some embodiments, the first tube body 20 includes a main tube body 22, a portion of which extends out of the housing 10. The retaining portion 21 is connected to one end of the main tube body 22 located outside the housing 10.

[0087] Another portion of the main body 22 may be located in the housing 10 and directly or indirectly connected to the housing 10 .

[0088] The main body 22 and the retaining portion 21 may be an integrally formed structure, or may be connected together by plugging, snapping, screwing or other suitable means.

[0089] At least a portion of the inner core 30 may be located within the main tube 22. Optionally, at least a portion of the inner core 30 is inserted into the second tube 40, and at least a portion of the second tube 40 is inserted into the main tube 22.

[0090] In the embodiment of the present application, the first tube body 20 is configured to include a main tube body 22 and a retaining portion 21. The main tube body 22 can be used to realize the socket connection between the first tube body 20 and the inner core 30 or the first tube body 20 and the second tube body 40, so as to facilitate the axial relative movement of the first tube body 20 and the inner core 30. At the same time, the structural restrictions on the retaining portion 21 are reduced, which is conducive to more flexible selection of the structural form of the retaining portion 21.

[0091] In some embodiments, the retaining portion 21 is a tubular structure, and a receiving cavity 211 is defined inside the retaining portion 21 . The receiving cavity 211 can receive the sheet-like implant 200 in a rolled state.

[0092] The accommodating cavity 211 may penetrate the holding portion 21 along the axial direction of the holding portion 21 , and the sheet-shaped implant 200 in a rolled state may be loaded into the accommodating cavity 211 from the axial end of the holding portion 21 .

[0093] The sheet-like implant 200 in the accommodating cavity 211 can be abutted against the inner circumferential wall of the retaining portion 21, and the retaining portion 21 can exert a radial limiting effect on the sheet-like implant 200 in the entire circumferential direction, thereby better preventing the sheet-like implant 200 in a wound state from unfolding, which is beneficial to improving the retaining effect of the retaining portion 21 on the wound state of the sheet-like implant 200.

[0094] In some embodiments, reference Figure 3 and Figure 5 The retaining portion 21 is fixedly sleeved on the outer side of the end of the main pipe body 22 , and the inner diameter of the retaining portion 21 is greater than the inner diameter of the main pipe body 22 .

[0095] Optionally, the holding portion 21 may be integrally formed with the main body 22, or may be fixedly connected to the main body 22 by threaded connection, clamping, welding or other suitable means. After the holding portion 21 is connected to the main body 22, the two may be non-detachable or detachable.

[0096] The inner diameter of the main body 22 is relatively small. When the inner core 30 is directly inserted into the main body 22, the gap between the inner core 30 and the main body 22 can be reduced, and the shaking during the axial relative movement of the two can be reduced. When the second tube 40 is inserted into the main body 22 and the inner core 30 is inserted into the second tube 40, the gap between the second tube 40 and the main body 22 can be reduced, and the shaking during the axial relative movement of the two can be reduced.

[0097] The inner diameter of the retaining portion 21 is relatively large, and the retaining portion 21 can form an expanded diameter portion of the first tube body 20, which is beneficial to reduce the possibility of interference between the retaining portion 21 and the sheet-like implant 200 in a wound state, and improve the smoothness of the sheet-like implant 200 in a wound state entering the retaining portion 21.

[0098] Figure 6 is a partial structural exploded schematic diagram of an implant device provided according to other embodiments of the present application. Figure 6 The holding part 21 is detachably connected to the main body 22. The inner core 30 is used to push the sheet-shaped implant 200 in the holding part 21 out of the holding part 21.

[0099] Optionally, the retaining portion 21 and the main body 22 may be detachably connected by threaded connection, snap connection or other suitable means.

[0100] For example, the inner diameter of the holding portion 21 may be greater than the inner diameter of the main tube 22. Alternatively, the inner diameter of the holding portion 21 may also be equal to or smaller than the inner diameter of the main tube 22.

[0101] Before implantation, the sheet-like implant 200 can be rolled and placed in the holding part 21, and then the holding part 21 is connected to the main tube 22. After the implant device 100 is inserted into the target tissue, the inner core 30 moves axially relative to the first tube 20 to push the sheet-like implant 200 in the holding part 21 to the target implantation position. Finally, the implant device 100 is withdrawn as a whole, and the holding part 21 can be discarded as a disposable part, which is convenient for cleaning the implant device 100 and helps improve the efficiency of the operation.

[0102] Figures 7a to 7c is a partial structural schematic diagram of an implant device in different states according to some embodiments of the present application, Figure 7b and Figure 7c The states shown are the same, for ease of understanding, Figure 7c Also shown is a sheet implant 200. In yet other embodiments, reference Figures 7a to 7c The retaining portion 21 includes at least one limiting strip 212 , which extends from the end of the main body 22 along the axial direction of the main body 22 in a direction away from the main body 22 , and the limiting strip 212 protrudes from the outer tube wall of the main body 22 along the radial direction of the main body 22 .

[0103] In this embodiment, when the sheet-shaped implant 200 and the limiting strip 212 are opposite to each other along the radial direction of the main tube 22 , the sheet-shaped implant 200 is located in the retaining portion 21 .

[0104] The number of the limiting strips 212 may be one or more. When there are more than one limiting strips 212 , the limiting strips 212 may be distributed at intervals along the outer circumference of the main tube 22 .

[0105] The limiting strip 212 may be formed integrally with the main body 22 , or may be connected to the end of the main body 22 by plugging, clamping, welding or other suitable means.

[0106] Before implantation, refer to Figure 7a, the support portion 311 is in the second state, and the support portion 311 and the limiting strip 212 can be at least partially staggered along the axial direction of the first tube body 20, so as to facilitate winding the sheet-like implant 200 on the support portion 311, and reduce the possibility of interference with the limiting strip 212 or entanglement with the limiting strip 212 during the winding process of the sheet-like implant 200. In the process of the support portion 311 switching to the first state, due to the axial relative movement between the support portion 311 and the sheet-like implant 200 supported thereon and the limiting strip 212, the limiting strip 212 can be pushed radially outward in the process of the support portion 311 switching to the first state, so as to reduce the obstruction of the limiting strip 212 on the sheet-like implant 200. After the support portion 311 switches to the first state radially opposite to the limiting strip 212, refer to Figure 7b and Figure 7c , and then loosen the limiting strip 212, the limiting strip 212 can press against the sheet-like implant 200 radially inward, thereby limiting the expansion of the sheet-like implant 200.

[0107] The limiting strip 212 extends along the axial direction of the main tube 22 , which can increase the contact area between the limiting strip 212 and the sheet-like implant 200 , thereby improving the state-maintaining effect of the sheet-like implant 200 .

[0108] The limiting strip 212 protrudes from the outer tube wall of the main tube body 22 along the radial direction of the main tube body 22, which can increase the distance between the limiting strip 212 and the central axis of the main tube body 22, which is beneficial to reduce the possibility of interference between the retaining portion 21 and the sheet-like implant 200 in the wound state, and improve the smoothness of the sheet-like implant 200 in the wound state entering the retaining portion 21.

[0109] In some embodiments, the implant device 100 further includes a driving mechanism, which is connected to the inner core 30 and / or the first tube body 20 and is used to drive the inner core 30 and / or the first tube body 20 to move axially along the first tube body 20 .

[0110] In one example, the driving mechanism may be connected only to the inner core 30 to drive the inner core 30 to move along the axial direction of the first tube body 20 .

[0111] In another example, the driving mechanism may also be connected only to the first tube body 20 to drive the first tube body 20 to move along its own axial direction.

[0112] In another example, the driving mechanism may also be connected to the inner core 30 and the first tube body 20 to drive the inner core 30 and the first tube body 20 to move independently along the axial direction of the first tube body 20 .

[0113] The driving mechanism can be a manually operated mechanism or an electric mechanism.

[0114] Optionally, the driving mechanism may be a cam mechanism, a turbine mechanism, a rack and pinion mechanism, a sliding mechanism, or the like.

[0115] In some embodiments, reference Figure 2 and Figure 4 The housing 10 includes two second openings 19, which are arranged opposite to each other along the radial direction of the first tube 20. The driving mechanism includes a first sub-driving mechanism 70, which includes two elastic arms 71, which are arranged opposite to each other along the radial direction of the first tube 20. Each elastic arm 71 is bent and bulged outward along the radial direction of the first tube 20, and the bent parts of the two elastic arms 71 are respectively exposed to the outside of the housing 10 through the two second openings 19. One end of the elastic arm 71 is connected to the housing 10, and the other end is connected to the inner core 30.

[0116] The first sub-driving mechanism 70 is at least partially disposed in the housing 10 .

[0117] The elastic arm 71 may be directly connected to the housing 10 , or may be indirectly connected to the housing 10 via other structures.

[0118] Optionally, the first sub-driving mechanism 70 further includes a connecting portion 72, and the elastic arm 71 can be indirectly connected to the housing 10 through the connecting portion 72. The connecting portion 72 and the elastic arm 71 can be integrally formed, or can be fixedly connected by means of a snap connection, a threaded connection, or the like.

[0119] The elastic arm 71 may be directly connected to the inner core 30 , or may be indirectly connected to the inner core 30 through other structures.

[0120] Optionally, the first sub-driving mechanism 70 further includes a sliding portion 73 , and the other ends of the two elastic arms 71 are both connected to the sliding portion 73 , and are indirectly connected to the inner core 30 through the sliding portion 73 .

[0121] A slot may be formed inside the sliding portion 73 , and the inner core 30 is inserted into the slot inside the sliding portion 73 .

[0122] The elastic arm 71, the connecting portion 72 and the sliding portion 73 may be integrally formed, or may be connected by plugging, welding or other suitable means.

[0123] Two sliding walls 15 are disposed in the housing 10 , and the two sliding walls 15 are opposite and spaced apart in the radial direction of the first tube 20 , and each sliding wall 15 extends in the axial direction of the first tube 20 . The sliding portion 73 slides in the axial direction of the first tube 20 between the two sliding walls 15 .

[0124] The sliding wall 15 can guide and restrict the sliding part 73, so that the sliding part 73 slides more smoothly and helps to reduce the phenomenon of skewing and deflection during the sliding process of the sliding part 73. The sliding part 73 can improve the stability of the inner core 30 during the axial movement process.

[0125] The elastic arms 71 are bent and convex outwardly along the radial direction of the first tube body 20. When the two elastic arms 71 are pressed toward each other, the two elastic arms 71 can be stretched and deformed along the axial direction of the first tube body 20, thereby causing the inner core 30 to extend out of the first tube body 20 or the second tube body 40. After the two elastic arms 71 are released, the two elastic arms 71 can be contracted along the axial direction of the first tube body 20 under the action of the elastic deformation restoring force, thereby driving the inner core 30 to move axially toward the inside of the first tube body 20 or the second tube body 40.

[0126] In the embodiment of the present application, the inner core 30 is driven to move axially by the first sub-driving mechanism 70. Compared with the first sub-driving mechanism 50, the first sub-driving mechanism 70 has a simpler structure and fewer components, which is conducive to simplifying the assembly process and reducing the matching errors between components, thereby improving the accuracy of the implantation position.

[0127] In some embodiments, the driving mechanism includes a second sub-driving mechanism, and the second sub-driving mechanism includes a sliding member 61 disposed on the housing 10, and the sliding member 61 is configured to be movable relative to the housing 10 along the axial direction of the first tube 20. One end of the first tube 20 in the axial direction is fixedly connected to the sliding member 61.

[0128] The sliding member 61 can slide axially under manual operation or under the drive of an electric mechanism.

[0129] Exemplarily, the second sub-driving mechanism may only include a sliding member 61 , and the sliding member 61 may slide axially under a pushing action, which is helpful to simplify the structure of the implant device 100 .

[0130] Alternatively, the second sub-driving mechanism may further include other components connected to the sliding member 61 .

[0131] The first tube body 20 can be fixedly connected to the sliding member 61 by means of plug-in, clamping, threaded connection, etc., so as to move synchronously with the sliding member 61 .

[0132] The second sub-driving mechanism and the first sub-driving mechanism 70 are independently arranged, and the axial movement of the first tube body 20 and the axial movement of the inner core 30 do not interfere with each other.

[0133] In some embodiments, a sliding groove 17 is provided in the housing 10, the sliding groove 17 extends along the axial direction of the first tube 20, and a portion of the sliding member 61 is provided in the sliding groove 17. The housing 10 is provided with a third opening 18, the third opening 18 connects the inside and the outside of the housing 10, and a portion of the sliding member 61 is exposed to the outside of the housing 10 through the third opening 18.

[0134] The sliding groove 17 can extend along the axial direction of the first tube 20. The sliding groove 17 can guide and restrict the sliding of the sliding member 61, so that the sliding of the sliding member 61 is smoother and helps to reduce the phenomenon of skewing and deflection during the sliding of the sliding member 61.

[0135] In some embodiments, the first opening 11 is disposed at one end of the housing 10 along the axial direction of the first tube 20. The second opening 19 and the third opening 18 are located on the same side of the housing 10, and are both disposed adjacent to the first opening 11 for easy operation.

[0136] According to the second aspect of the present application, the present embodiment further provides an implantation system, which includes an implantation device 100 provided in any embodiment of the present application and a sheet-like implant 200. The sheet-like implant 200 is configured to be wound and arranged, and the sheet-like implant 200 is detachably arranged on the holding portion 21 of the implantation device 100.

[0137] Before implantation, the sheet implant 200 can be rolled into a coiled state and placed on the holding portion 21. During the implantation process, the sheet implant 200 is kept in a coiled state and not unfolded under the action of the holding portion 21, which can minimize the size of the head of the implantation device 100, thereby making the implantation wound as small as possible, which is conducive to reducing surgical trauma. After the implantation device 100 implants the sheet implant 200 into the target position, the sheet implant 200 is separated from the holding portion 21 through the inner core 30, and the sheet implant 200 can be exposed to the target position and unfolded after absorbing water and swelling, thereby achieving effective implantation of the sheet implant 200.

[0138] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. An implantation device for implanting a sheet-like implant, characterized in that: The implant device comprises: A housing having a first opening; A first tube body connected to the housing, at least a portion of the first tube body extending out of the housing through the first opening, the first tube body having a holding portion located outside the housing, the holding portion being configured to hold the sheet-like implant in the holding portion in a rolled state; and An inner core, at least a portion of which is located in the first tube body, and the inner core is configured to be movably arranged relative to the first tube body along the axial direction of the first tube body, and to enable the sheet-like implant in a rolled state to be separated from the retaining portion.

2. The implant device according to claim 1, characterized in that The inner core has a support portion at one end along the axial direction of the first tube, and the support portion can support the sheet-like implant in a rolled state; The support portion has a first state and a second state. In the first state, the retaining portion is located outside the support portion in the radial direction of the first tube body. In the second state, the support portion and the retaining portion are at least partially offset in the axial direction of the first tube body.

3. The implant device according to claim 2, characterized in that The support portion comprises two elastic clamping arms, which are separately arranged and opposite to each other along the radial direction of the first tube body, and the two elastic clamping arms are configured to elastically deform in directions approaching and / or moving away from each other; In the first state, the two elastic clamp arms are closed and can clamp the sheet-shaped implant; in the second state, the two elastic clamp arms are open and can release the sheet-shaped implant.

4. The implant device according to claim 3, characterized in that The implant device also includes a second tube body, which is inserted into the first tube body, and at least a portion of the inner core is inserted into the second tube body. The inner core is configured to be movably arranged relative to the second tube body along the axial direction of the first tube body to close the two elastic clamp arms through the second tube body.

5. The implant device according to claim 1, characterized in that The first tube body includes a main tube, a portion of which extends out of the shell; The retaining portion is connected to one end of the main pipe located outside the shell.

6. The implant device according to claim 5, characterized in that The holding portion is a tubular structure, and a receiving cavity is defined inside the holding portion, and the receiving cavity can receive the sheet-shaped implant in a rolled state.

7. The implant device according to claim 6, characterized in that The retaining portion is detachably connected to the main pipe; The inner core is used to push the sheet-shaped implant in a rolled state in the holding portion out of the holding portion.

8. The implant device according to claim 6, characterized in that The retaining portion is fixedly sleeved on the outer side of the end portion of the main pipe body, and the inner diameter of the retaining portion is greater than the inner diameter of the main pipe body.

9. The implant device according to claim 5, characterized in that The retaining portion includes at least one limiting strip, which extends from the end of the main tube along the axial direction of the main tube toward a direction away from the main tube, and protrudes from the outer tube wall of the main tube along the radial direction of the main tube.

10. The implant device according to claim 1, characterized in that The implant device further comprises a driving mechanism, which is connected to the inner core and / or the first tube body and is used for driving the inner core and / or the first tube body to move along the axial direction of the first tube body.

11. The implant device according to claim 10, characterized in that The housing comprises two second openings, and the two second openings are arranged opposite to each other along the radial direction of the first tube body; The driving mechanism comprises a first sub-driving mechanism, the first sub-driving mechanism comprises two elastic arms, the two elastic arms are arranged opposite to each other along the radial direction of the first tube body, each of the elastic arms is bent and protrudes outward along the radial direction of the first tube body, and the bent parts of the two elastic arms are respectively exposed to the outside of the shell through the two second openings; One end of the elastic arm is connected to the shell, and the other end is connected to the inner core.

12. The implant device according to claim 10, characterized in that The driving mechanism comprises a second sub-driving mechanism, the second sub-driving mechanism comprises a sliding member provided on the housing, the sliding member is configured to be movably provided relative to the housing along the axial direction of the first tube; One axial end of the first tube is fixedly connected to the sliding member.

13. The implant device according to claim 12, characterized in that A sliding groove is provided in the housing, the sliding groove extends along the axial direction of the first tube body, and a part of the sliding member is provided in the sliding groove; The shell is provided with a third opening, the third opening communicates the inside and the outside of the shell, and a part of the sliding member is exposed to the outside of the shell through the third opening.

14. An implant system, characterized in that: include: An implant device according to any one of claims 1 to 13; as well as The sheet-shaped implant is configured to be rolled up and can be detachably arranged on the holding portion of the implant device.

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