Moisturizing and whitening body lotion and preparation method thereof

Abstract

The invention discloses a moisturizing and whitening body lotion and a preparation method thereof, and belongs to the technical field of cosmetics. Comprising the following steps: adding moisturizing and whitening body lotion into a nutrient solution, carrying out vacuum concentration, filtering, and taking a solid phase to prepare an intermediate; taking gamma-polyglutamic acid, L-lysine and deionized water, mixing, stirring for 10-12min, adding methyl dihydrojasmonate and sodium alginate, stirring for 10-15min, then adding the intermediate, N-hydroxysuccinimide, carbomer and polysaccharide powder, continuously stirring for 10-12min, transferring into a template, freezing the template in an environment of-20 DEG C for 6-8h, taking out, melting at room temperature for 2-3h, cooling to room temperature, taking out, and drying to obtain the polyglutamic acid-L-lysine composite material. And repeatedly freezing and thawing for 3-4 times to obtain the moisturizing and whitening body lotion, so that the moisturizing and whitening effects of the skin are improved.

Description

Technical Field

[0001] The invention belongs to the technical field of cosmetics, and particularly relates to a moisturizing and whitening body lotion and a preparation method thereof. Background Art

[0002] With the improvement of people's living standards and the enhancement of aesthetic concepts, the requirements for skin care are getting higher and higher. In the field of cosmetics, moisturizing and whitening body lotion, as one of the important products for daily skin care, has been favored by consumers. However, there are many types of moisturizing and whitening body lotions on the market, and the quality is uneven. Many products have problems such as poor moisturizing effect and easy oxidation of whitening ingredients. Therefore, it is of great practical significance to develop a moisturizing and whitening body lotion with good moisturizing effect, lasting whitening effect, safety and no irritation. Summary of the invention

[0003] The invention aims to provide a moisturizing and whitening body lotion and a preparation method thereof, so as to improve the moisturizing and whitening effect of the skin.

[0004] The purpose of the present invention can be achieved through the following technical solutions:

[0005] A method for preparing a moisturizing and whitening body lotion comprises the following steps:

[0006] S1. Add moisturizing and whitening body lotion to the nutrient solution, vacuum concentrate, filter, and take the solid phase to obtain an intermediate;

[0007] S2. Mix γ-polyglutamic acid, L-lysine and deionized water, stir for 10-12 minutes, add methyl dihydrojasmonate and sodium alginate, stir for 10-15 minutes, then add the intermediate, N-hydroxysuccinimide, carbomer and polysaccharide powder, continue stirring for 10-12 minutes, transfer into a template, freeze the template in a -20°C environment for 6-8 hours, take it out, thaw it at room temperature for 2-3 hours, repeat freezing and thawing 3-4 times to obtain the moisturizing and whitening body lotion.

[0008] As a preferred technical solution of the present invention, in step S1, the mass ratio of the moisturizing and whitening body lotion to the nutrient solution is 3-5:18-25.

[0009] As a preferred technical solution of the present invention, in step S2, the mass ratio of the γ-polyglutamic acid, L-lysine, deionized water, methyl dihydrojasmonate, sodium alginate, intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder is 0.7-0.9: 0.3-0.4: 50: 0.1-0.2: 8-10: 0.1-0.12: 0.08-0.1: 1-2.

[0010] As a preferred technical solution of the present invention, the preparation of the nutrient solution comprises the following steps:

[0011] The nutrient solution is obtained by mixing licorice extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water, and performing ultrasonic dispersion for 5-8 minutes.

[0012] As a preferred technical solution of the present invention, the mass ratio of the glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 9-11:5-6:3-4:2-3:4-6:1-2:15-20:12-16:50.

[0013] As a preferred technical solution of the present invention, the preparation of the polysaccharide powder comprises the following steps:

[0014] Wash shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone, cut into pieces, mix, add deionized water, extract in a water bath at 75-85° C. for 4-5 hours, decolorize, centrifuge, filter, and vacuum dry the solid phase to obtain the polysaccharide powder.

[0015] As a preferred technical solution of the present invention, the mass ratio of shiitake mushroom, oyster mushroom, king oyster mushroom, tremella, ganoderma lucidum and cuttlebone is 4-6:2-3:2-3:1-2:0.4-0.6:0.5-0.6.

[0016] As a preferred technical solution of the present invention, in step S1, the vacuum concentration refers to vacuum concentration at -0.098 MPa and 40-50°C for 6-8 hours.

[0017] As a preferred technical solution of the present invention, the vacuum drying refers to vacuum drying at -0.098MPa and 40-50°C for 8-10h.

[0018] As a preferred technical solution of the present invention, the sources of the above-mentioned raw materials are as follows:

[0019] The moisturizing and whitening body lotion was purchased from Wuhan Lanabai Pharmaceutical Chemical Co., Ltd., γ-polyglutamic acid was purchased from Wuhan Dongkangyuan Technology Co., Ltd., L-lysine was purchased from Hangzhou Pingao Chemical Co., Ltd., methyl dihydrojasmonate was purchased from Henan Xiangduo Industrial Co., Ltd., sodium alginate was purchased from Nanjing Songguan Biotechnology Co., Ltd., N-hydroxysuccinimide was purchased from Chengdu Huaxia Chemical Reagent Co., Ltd., carbomer was purchased from Hebei Yanxi Chemical Co., Ltd., Glycyrrhiza glabra extract was purchased from Chongqing Jiaowang Natural Products Co., Ltd., arbutin was purchased from Xi'an Kangnuo Chemical Co., Ltd., green tea extract was purchased from Nanjing Zhenweikang Biotechnology Co., Ltd., chrysanthemum extract was purchased from Changsha Shanghe Biotechnology Co., Ltd., pomegranate extract was purchased from Huatesheng Biotechnology (Wuhan) Co., Ltd., rhodiola rosea extract was purchased from Xi'an Tianyi Biotechnology Co., Ltd., white water lily extract was purchased from Rudong Lianfeng Chemical Co., Ltd., and Centella asiatica extract was purchased from Guilin Yitiancheng Biotechnology Co., Ltd.

[0020] The moisturizing and whitening body lotion is prepared by the above preparation method.

[0021] Beneficial effects of the present invention:

[0022] The moisturizing and whitening body lotion and the preparation method thereof disclosed in the present invention can significantly improve the skin's water-locking and moisturizing effect through the synergistic effect of hydrolyzing sclerotium gum, γ-polyglutamic acid and L-lysine;

[0023] In addition, the plant ingredients such as Licorice Extract, Arbutin, Green Tea Extract, Chrysanthemum Extract, Pomegranate Extract, Rhodiola Rosea Extract, White Water Lily Extract and Centella Asiatica Extract work synergistically in skin care products to repair the skin, promote absorption and consolidate the moisturizing and whitening effects;

[0024] Furthermore, the polysaccharide powder extracted from shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone promotes skin absorption and moisture retention, provides nutrients required by the skin, promotes skin health, and improves the skin's moisturizing and whitening effects. DETAILED DESCRIPTION

[0025] In order to further illustrate the technical means and effects adopted by the present invention to achieve the predetermined invention purpose, the specific implementation methods, structures, features and effects of the present invention are described in detail below in combination with the embodiments.

[0026] Example 1

[0027] A method for preparing a moisturizing and whitening body lotion comprises the following steps:

[0028] S1. Add moisturizing and whitening body lotion to the nutrient solution, concentrate under vacuum at -0.098 MPa and 40°C for 8 hours, filter, take the solid phase, and obtain an intermediate; the mass ratio of the moisturizing and whitening body lotion to the nutrient solution is 3:18;

[0029] S2, mix γ-polyglutamic acid, L-lysine, and deionized water, stir for 10 minutes, add methyl dihydrojasmonate and sodium alginate, stir for 10 minutes, then add the intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder, continue stirring for 10 minutes, transfer to a template, freeze the template in a -20°C environment for 6 hours, take it out, thaw it at room temperature for 2 hours, repeat freezing and thawing 3 times to obtain the moisturizing and whitening body lotion; the mass ratio of γ-polyglutamic acid, L-lysine, deionized water, methyl dihydrojasmonate, sodium alginate, intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder is 0.7:0.3:50:0.1:8:0.1:0.08:1;

[0030] The preparation of the nutrient solution comprises the following steps:

[0031] Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water are mixed and ultrasonically dispersed for 5-8 minutes to obtain the nutrient solution; the mass ratio of the glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 9:5:3:2:4:1:15:12:50;

[0032] The preparation of the polysaccharide powder comprises the following steps:

[0033] Wash shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone, cut into pieces, mix, add 80 parts by mass of deionized water, extract in a 75°C water bath for 5 hours, decolorize, centrifuge, filter, and take the solid phase and vacuum dry it at -0.098MPa and 40°C for 10 hours to obtain the polysaccharide powder; the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone is 4:2:2:1:0.4:0.5.

[0034] Example 2

[0035] A method for preparing a moisturizing and whitening body lotion comprises the following steps:

[0036] S1. Add moisturizing and whitening body lotion to the nutrient solution, concentrate under vacuum at -0.098 MPa and 45°C for 7 hours, filter, take the solid phase, and obtain an intermediate; the mass ratio of the moisturizing and whitening body lotion to the nutrient solution is 4:22;

[0037] S2, taking γ-polyglutamic acid, L-lysine, and deionized water, mixing, stirring for 11 minutes, adding methyl dihydrojasmonate and sodium alginate, stirring for 12 minutes, and then adding the intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder, continuing to stir for 11 minutes, transferring into a template, freezing the template in a -20°C environment for 7 hours, taking it out, thawing it at room temperature for 2.5 hours, and repeatedly freezing and thawing it 3 times to obtain the moisturizing and whitening body lotion; the mass ratio of the γ-polyglutamic acid, L-lysine, deionized water, methyl dihydrojasmonate, sodium alginate, intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder is 0.8:0.35:50:0.15:9:0.11:0.09:1.5;

[0038] The preparation of the nutrient solution comprises the following steps:

[0039] Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water are mixed and ultrasonically dispersed for 7 minutes to obtain the nutrient solution; the mass ratio of the glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 10:5.5:3.5:2.5:5:1.5:18:14:50;

[0040] The preparation of the polysaccharide powder comprises the following steps:

[0041] Wash shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone, mix them, add 80 parts by mass of deionized water, extract them in a water bath at 80°C for 4.5 hours, decolorize, centrifuge, filter, and vacuum dry the solid phase at -0.098 MPa and 45°C for 9 hours to obtain the polysaccharide powder; the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone is 5:2.5:2.5:1.5:0.5:0.55.

[0042] Example 3

[0043] A method for preparing a moisturizing and whitening body lotion comprises the following steps:

[0044] S1. Add moisturizing and whitening body lotion to the nutrient solution, concentrate under vacuum at -0.098 MPa and 50°C for 6 hours, filter, take the solid phase, and obtain an intermediate; the mass ratio of the moisturizing and whitening body lotion to the nutrient solution is 5:25;

[0045] S2, taking γ-polyglutamic acid, L-lysine, and deionized water, mixing, stirring for 12 minutes, adding methyl dihydrojasmonate and sodium alginate, stirring for 15 minutes, then adding the intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder, continuing to stir for 12 minutes, transferring into a template, freezing the template in a -20°C environment for 8 hours, taking it out, thawing it at room temperature for 3 hours, and repeating freezing and thawing 4 times to obtain the moisturizing and whitening body lotion; the mass ratio of the γ-polyglutamic acid, L-lysine, deionized water, methyl dihydrojasmonate, sodium alginate, intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder is 0.9:0.4:50:0.2:10:0.12:0.1:2;

[0046] The preparation of the nutrient solution comprises the following steps:

[0047] Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water are mixed and ultrasonically dispersed for 8 minutes to obtain the nutrient solution; the mass ratio of the glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 11:6:4:3:6:2:20:16:50;

[0048] The preparation of the polysaccharide powder comprises the following steps:

[0049] Wash shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone, mix them, add 80 parts by mass of deionized water, extract them in a water bath at 85°C for 4 hours, decolorize, centrifuge, filter, and vacuum dry the solid phase at -0.098MPa and 50°C for 8 hours to obtain the polysaccharide powder; the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone is 6:3:3:2:0.6:0.6.

[0050] Comparative Example 1

[0051] The difference from Example 3 is that no moisturizing and whitening body lotion is added in step S1.

[0052] Comparative Example 2

[0053] The difference from Example 3 is that only γ-polyglutamic acid is added in step S2.

[0054] Comparative Example 3

[0055] The difference from Example 3 is that only L-lysine is added in step S2.

[0056] Comparative Example 4

[0057] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract, and deionized water is 0:17:4:3:6:2:20:16:50.

[0058] Comparative Example 5

[0059] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract, and deionized water is 11:0:10:3:6:2:20:16:50.

[0060] Comparative Example 6

[0061] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 11:10:0:3:6:2:20:16:50.

[0062] Comparative Example 7

[0063] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 11:6:7:0:6:2:20:16:50.

[0064] Comparative Example 8

[0065] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 11:6:4:9:0:2:20:16:50.

[0066] Comparative Example 9

[0067] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 11:6:4:3:8:0:20:16:50.

[0068] Comparative Example 10

[0069] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 11:6:4:3:6:22:0:16:50.

[0070] Comparative Example 11

[0071] The difference from Example 3 is that in the preparation of the nutrient solution, the mass ratio of the Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract, Centella asiatica extract, and deionized water is 11:6:4:3:6:18:20:0:50.

[0072] Comparative Example 12

[0073] The difference from Example 3 is that in the preparation of the polysaccharide powder, the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, tremella, ganoderma lucidum and cuttlebone is 0:9:3:2:0.6:0.6.

[0074] Comparative Example 13

[0075] The difference from Example 3 is that in the preparation of the polysaccharide powder, the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, tremella, ganoderma lucidum and cuttlebone is 9:0:3:2:0.6:0.6.

[0076] Comparative Example 14

[0077] The difference from Example 3 is that in the preparation of the polysaccharide powder, the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, tremella, ganoderma lucidum and cuttlebone is 6:3:0:5:0.6:0.6.

[0078] Comparative Example 15

[0079] The difference from Example 3 is that in the preparation of the polysaccharide powder, the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, tremella, ganoderma lucidum and cuttlebone is 6:3:3:0:2.6:0.6.

[0080] Comparative Example 16

[0081] The difference from Example 3 is that in the preparation of the polysaccharide powder, the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, tremella, ganoderma lucidum and cuttlebone is 6:3:3:2:0:1.2.

[0082] Comparative Example 17

[0083] The difference from Example 3 is that in the preparation of the polysaccharide powder, the mass ratio of shiitake mushrooms, oyster mushrooms, king oyster mushrooms, tremella, ganoderma lucidum and cuttlebone is 6:3:3:2:1.2:0.

[0084] Performance Testing

[0085] Test Example 1

[0086] A safety test was conducted on the moisturizing and whitening body lotions prepared in the above Examples 1-3 and Comparative Examples 1-17. 100 healthy rabbits weighing 2kg-3kg were randomly selected and randomly divided into 20 groups, 5 rabbits in each group, and fed in a single cage. Each group corresponded to a moisturizing and whitening body lotion in the Examples and Comparative Examples respectively.

[0087] 24 hours before the experiment, the hair on both sides of the midline of the back of the rabbits was removed (the hair removal area was not less than 10% of the body surface area), and the skin was carefully inspected to ensure that it was intact;

[0088] Apply 6g of moisturizing and whitening body lotion to the hairless skin of each rabbit, cover the applied skin with cellophane and two layers of gauze, and fix it with a non-irritating bandage. Remove the cellophane, gauze and bandage after 24 hours, wash off the residual moisturizing and whitening body lotion on the skin with warm water, observe and record whether the rabbit has abnormal reactions (such as drowsiness, abnormal calls, sluggishness, convulsions, tremors, excitement, muscle rigidity, tears, diarrhea, dirty urine, red skin, skin wrinkles, skin sagging, rash, stool shape and color, etc.), whether there is death and analyze the cause of death;

[0089] A 14-day smear test was conducted to observe growth, body weight, food utilization, hematological and blood biochemical indices, and pathological changes in the eyes, heart, liver, spleen, lungs, kidneys, stomach, intestines, etc. were observed by autopsy. The organ system values ​​of the liver, kidney, spleen, testicles (male), and ovaries (female) were measured, and the organ system value (organ / body weight × 100%) was calculated.

[0090] Test results: All the tested rabbits grew and developed well, and their behavior, mental state, coat color, eating, drinking, and urination were normal, indicating that the moisturizing and whitening body lotions of the embodiments and comparative examples had no adverse effects on the general condition of the rabbits, had no adverse effects on the weight gain and growth and development of the rabbits, had no adverse effects on food utilization, had no adverse effects on the basic indicators of hematology, had no adverse effects on the main indicators of blood biochemistry, and had no adverse effects on the major organs.

[0091] It is explained that the moisturizing and whitening body lotion of the present application has no acute toxic side effects, and long-term application has no adverse effects on weight gain, food utilization, hematology, organs and other indicators, and can be applied for a long time.

[0092] Test Example 2

[0093] Human patch test

[0094] 1. Test substance: product of Example 1.

[0095] 2. Negative control: blank control.

[0096] 3. Subjects: A total of 30 subjects, including 3 males and 27 females, aged 18-59 years old, with an average age of 37.2±10.6 years old, who met the voluntary inclusion criteria.

[0097] 4. Patch test method: Select qualified patch test equipment and use the closed patch test method. Place about 0.020g-0.025g of the test substance in the patch tester and apply it to the back of the subject with low-allergenic tape. Remove the test substance after 24 hours and observe the skin reaction at 0.5, 24, and 48 hours after removal. Record the results according to the skin reaction grading standards in the current valid technical specifications.

[0098] 5. Experimental results:

[0099]

[0100]

[0101] 6. Skin reaction grading standards:

[0102]

[0103] The moisturizing and whitening body lotion of the present application has no adverse reaction to human skin; the inventor of the present application repeated the above test using samples prepared in other embodiments and comparative examples, and the test results were the same as above, all of which had no adverse reaction to human skin.

[0104] Test Example 3

[0105] 100 volunteers with healthy skin were randomly selected (with a male-female ratio of 1:1) and randomly divided into 20 groups, with 5 people in each group, and each group corresponded to a moisturizing and whitening body lotion in the embodiment and the comparative example;

[0106] Each volunteer cleansed his / her facial skin with a facial cleanser, wiped it dry, and then cleaned his / her facial skin with clean water and wiped it dry. 20 test groups respectively took 1 g of the moisturizing and whitening body lotion prepared in the above Examples 1-3 and Comparative Examples 1-17, dissolved it in 100 mL of deionized water to make a slurry and evenly applied it on the face, and patted the facial skin for 30 seconds for testing, and took the average value;

[0107] After the moisture on the face dries naturally, use a skin detector to measure the moisture content A of the facial skin at room temperature of 25°C and humidity of 60%; sit still indoors for 1 hour, and measure the moisture content B of the facial skin again under the same conditions to calculate the moisture retention rate. The higher the moisture retention rate, the better the water-locking performance;

[0108] After comparison, statistical analysis was performed, and the comparison results of each group showed that P<0.05, the difference was statistically significant;

[0109] Water retention rate = B ÷ A × 100%

[0110] The test results are shown in Table 1 below;

[0111] Table 1

[0112]

[0113]

[0114] Test results: The moisturizing and whitening body lotion prepared in Examples 1-3 has good moisturizing and water-locking properties; the present application can significantly improve the skin's water-locking and moisturizing effect through the synergistic effect of hydrolyzed sclerotinia gum, γ-polyglutamic acid and L-lysine. This is because the hydrophilicity of the polysaccharide chain of hydrolyzed sclerotinia gum can absorb a large amount of water to form a hydration layer, thereby locking the moisture in the skin, and γ-polyglutamic acid is a natural polyamino acid with good hygroscopicity and film-forming properties. It can absorb moisture and form a protective film, effectively locking the moisture of the skin, and at the same time can promote the recovery of the skin barrier function. L-lysine further consolidates the moisturizing effect, enhances the hydration of the skin, and helps maintain the moisture balance of the skin. The strong hygroscopicity of hydrolyzed sclerotium gum and γ-polyglutamic acid can absorb moisture from the environment and transfer moisture to the deep layers of the skin. γ-polyglutamic acid forms a protective film on the surface of the skin to prevent moisture evaporation and increase the moisture retention of the skin. L-lysine can promote the skin's absorption of moisture and improve the ability of moisture to penetrate into the deep layers of the skin. Through the above synergistic effect, hydrolyzed sclerotium gum, γ-polyglutamic acid and L-lysine can effectively improve the skin's water-locking and moisturizing effect, making the skin more hydrated and smooth.

[0115] In addition, plant ingredients such as licorice extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract and Centella asiatica extract work synergistically in skin care products to repair the skin, promote absorption and consolidate the moisturizing effect. Licorice extract has powerful antioxidant and anti-inflammatory effects, which can protect the skin from damage by free radicals and inflammation and promote skin repair; arbutin can inhibit the activity of tyrosinase and reduce the production of melanin. It also has anti-inflammatory and antioxidant properties, which helps repair and whiten the skin; green tea extract is rich in catechins, which have antioxidant, anti-inflammatory and antibacterial effects, which helps reduce skin Skin damage and promote skin health; chrysanthemum extract, pomegranate extract, rhodiola rosea extract, and white water lily extract help soothe the skin, reduce redness and inflammation, protect the skin from damage by free radicals, promote skin repair, help the skin resist environmental stress, promote cell repair, Centella asiatica extract enhances the skin barrier, and the above extracts work synergistically to repair and enhance the skin barrier, reduce water loss, and increase the skin's resistance to external stimuli. Arbutin and green tea extract can promote the absorption of other active ingredients, improve the effect of the entire product, provide lasting moisturizing effect, stimulate collagen production, and enhance skin structure and elasticity.

[0116] Furthermore, the polysaccharide powder extracted from shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone promotes skin absorption and moisture retention, provides nutrients required by the skin, and promotes skin health.

[0117] Test Example 4

[0118] 85 volunteers aged 30-45 with dry skin problems were selected, with a male to female ratio of 40:45. They were randomly divided into 17 groups, with 5 volunteers in each group. The moisturizing and whitening body lotions in Examples 1-3 and Comparative Examples 4-17 were used respectively. The moisturizing and whitening body lotion samples were applied to a 4 cm×4 cm area on the inner side of the left forearm of the volunteers as the test area. During the experiment, the volunteers could not apply any cosmetics on the experimental area. The method of use was to use it once in the morning and evening every day for 28 days.

[0119] Wash the applied area before and after use, and use a pigment test probe to test the melanin content of the test area on the 0th day and 28th day after using the product. Test three times and take the average result;

[0120] The results are shown in Table 2.

[0121] Table 2

[0122]

[0123]

[0124] Test results: The moisturizing and whitening body lotion prepared in Examples 1-3 can significantly reduce the MI value, and the melanin content in the skin is significantly reduced; while the moisturizing and whitening body lotion prepared in Comparative Examples 4-17 has a reduced MI value, but the reduction is less, and the melanin content in the skin is still high. Studies have found that this is because Glycyrrhiza glabra extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, Rhodiola rosea extract, white water lily extract and Centella asiatica extract have a synergistic effect in whitening skin care, which can inhibit tyrosinase activity, thereby reducing the production of melanin; they are rich in antioxidant ingredients, such as vitamin C, vitamin E, polyphenol compounds, etc., which can neutralize free radicals and reduce oxidative stress damage to the skin, thereby reducing the production of melanin; these extracts have anti-inflammatory effects and can reduce pigmentation caused by inflammatory reactions; by promoting cell renewal, these extracts can accelerate the production of melanin. Aging cells fall off, thereby reducing the accumulation of melanin on the skin surface; Licorice extract contains glycyrrhizic acid, arbutin, catechins contained in green tea extract and other ingredients, which can directly inhibit the activity of tyrosinase and reduce the formation of melanin. At the same time, it has anti-inflammatory and antioxidant properties and promotes the decomposition of melanin; Pomegranate extract, Rhodiola rosea extract, White Water Lily extract, Centella asiatica extract have the effect of promoting cell renewal and anti-inflammatory, can reduce the production of melanin, promote cell metabolism, accelerate the renewal and shedding of melanin-containing cells, play a synergistic whitening effect, effectively inhibit the production of melanin in the skin, and achieve the purpose of whitening and brightening the skin tone;

[0125] Furthermore, the mixed polysaccharide powder extracted from shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma and cuttlefish contains a variety of bioactive ingredients, which can promote the absorption of nutrients in the extracts by skin cells, promote the exchange of substances inside and outside the cells, stimulate cell vitality, promote cell metabolism, and enhance the cell's ability to absorb nutrients; collagen is an important protein for maintaining skin elasticity and firmness. Polysaccharides can promote the production of collagen, improve skin texture, improve skin microcirculation, increase blood flow, provide skin cells with more oxygen and nutrients, promote cell health, and protect cells from oxidative stress, thereby maintaining the normal function of cells, promoting the degradation and excretion of melanin, and thus enhancing the whitening effect.

[0126] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Although the present invention has been disclosed as a preferred embodiment as above, it is not used to limit the present invention. Any technical personnel in this field can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A method for preparing a moisturizing and whitening body lotion, characterized in that: The following steps are involved: S1. Add moisturizing and whitening body lotion to the nutrient solution, vacuum concentrate, filter, and take the solid phase to obtain an intermediate; S2. Mix γ-polyglutamic acid, L-lysine and deionized water, stir for 10-12 minutes, add methyl dihydrojasmonate and sodium alginate, stir for 10-15 minutes, then add the intermediate, N-hydroxysuccinimide, carbomer and polysaccharide powder, continue stirring for 10-12 minutes, transfer into a template, freeze the template in a -20°C environment for 6-8 hours, take it out, thaw it at room temperature for 2-3 hours, repeat freezing and thawing 3-4 times to obtain the moisturizing and whitening body lotion.

2. The method for preparing a moisturizing and whitening body lotion according to claim 1, characterized in that: In step S1, the mass ratio of the moisturizing and whitening body lotion to the nutrient solution is 3-5:18-25.

3. The method for preparing a moisturizing and whitening body lotion according to claim 1, characterized in that: In step S2, the mass ratio of the γ-polyglutamic acid, L-lysine, deionized water, methyl dihydrojasmonate, sodium alginate, intermediate, N-hydroxysuccinimide, carbomer, and polysaccharide powder is 0.7-0.9: 0.3-0.4: 50: 0.1-0.2: 8-10: 0.1-0.12: 0.08-0.1: 1-2.

4. The method for preparing a moisturizing and whitening body lotion according to claim 1, characterized in that: The preparation of the nutrient solution comprises the following steps: The nutrient solution is obtained by mixing licorice extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water, and performing ultrasonic dispersion for 5-8 minutes.

5. The method for preparing a moisturizing and whitening body lotion according to claim 4, characterized in that: The mass ratio of the licorice extract, arbutin, green tea extract, chrysanthemum extract, pomegranate extract, rhodiola rosea extract, white water lily extract, Centella asiatica extract and deionized water is 9-11:5-6:3-4:2-3:4-6:1-2:15-20:12-16:

50.

6. The method for preparing a moisturizing and whitening body lotion according to claim 1, characterized in that: The preparation of the polysaccharide powder comprises the following steps: Wash shiitake mushrooms, oyster mushrooms, king oyster mushrooms, white fungus, ganoderma lucidum, and cuttlebone, cut into pieces, mix, add deionized water, extract in a water bath at 75-85° C. for 4-5 hours, decolorize, centrifuge, filter, and vacuum dry the solid phase to obtain the polysaccharide powder.

7. The method for preparing a moisturizing and whitening body lotion according to claim 6, characterized in that: The mass ratio of shiitake mushroom, oyster mushroom, king oyster mushroom, white fungus, ganoderma lucidum and cuttlebone is 4-6:2-3:2-3:1-2:0.4-0.6:0.5-0.

6.

8. The method for preparing a moisturizing and whitening body lotion according to claim 1, characterized in that: In step S1, the vacuum concentration refers to vacuum concentration at -0.098 MPa and 40-50° C. for 6-8 hours.

9. The method for preparing a moisturizing and whitening body lotion according to claim 6, characterized in that: The vacuum drying refers to vacuum drying at -0.098 MPa and 40-50° C. for 8-10 hours.

10. A moisturizing and whitening body lotion prepared according to the preparation method according to any one of claims 1 to 9.

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