Real-time control method and system for accurate intraoperative fluid infusion based on patient weight changes

Abstract

The present application discloses a method and system for real-time control of intraoperative precise fluid infusion based on patient weight changes, which relates to the field of medical information technology. The present application comprehensively considers the impact of multiple factors on the patient's intraoperative weight, and obtains a more accurate actual amount of bleeding based on the flushing fluid, body fluid collector, and gauze used in the operation; based on the weight of surgical instruments, urine output, actual amount of bleeding, surgically removed tissue weight, and the patient's intraoperative weight changes, the actual intraoperative weight change data of the patient is calculated, which effectively assists doctors in making fluid infusion judgments, maintains the patient's ideal blood volume and internal environment stability, reduces the risk of related complications such as heart failure, shock, and coagulation dysfunction, and improves the safety of the operation period; quickly judges the patient's current fluid infusion volume and fluid infusion speed, and promptly feeds back to the monitoring screen to prevent the risk of related complications caused by insufficient blood volume in the patient's body, and can help promote the patient's rapid recovery after surgery.

Description

Technical Field

[0001] The present invention relates to the field of medical information technology, and in particular to a method and system for real-time control of precise intraoperative fluid infusion based on patient weight changes. Background Art

[0002] During surgery, fluid replacement is an important means to maintain the patient's blood volume and electrolyte balance. Fluid replacement can not only maintain the patient's blood volume and electrolyte balance during surgery, but is also important for maintaining stable vital signs during surgery. Appropriate fluid replacement can reduce the risk of perioperative complications, such as shock, heart failure, coagulation disorders, etc., and will also help patients recover quickly after surgery.

[0003] To determine whether the patient needs fluid replacement, how much to replace, and how fast to replace during surgery, most of the existing technologies are manual methods. Doctors need to make a rough estimate based on factors such as the patient's blood pressure, blood loss, and preoperative data to determine the ratio, amount, and speed of fluid replacement. However, during the operation, the situation is more complicated, and the patient is often in a state of continuous multi-channel loss of body fluid and continuous intravenous rehydration. The amount of fluid replacement required by the patient will change according to changes in the internal environment. Insufficient, excessive, or too fast fluid replacement may endanger the patient's life. Insufficient fluid replacement may lead to insufficient blood volume, hypotension, renal damage, and even shock. On the contrary, too fast or too much fluid replacement may cause systemic edema, pulmonary edema, heart failure, etc., especially in patients with cardiovascular diseases or renal insufficiency. Therefore, there is a lack of a method to assist doctors in making fluid replacement judgments during surgery and to provide real-time feedback on the patient's weight change data and other data. Summary of the invention

[0004] The purpose of the present invention is to provide a method and system for real-time control of precise fluid infusion during surgery based on changes in patient weight, so as to improve the above-mentioned technical problems.

[0005] In order to achieve the above-mentioned object of the invention, the embodiment of the present invention provides the following technical solutions:

[0006] A method for real-time control of intraoperative precise fluid infusion based on patient weight changes, comprising:

[0007] S1. Obtain the patient's preoperative information and set a scheduled data upload time; wherein the patient's preoperative information includes preoperative weight, blood pressure, hemoglobin cell concentration in the body, red blood cell count, heart rate and body temperature; the preoperative weight includes the patient's weight after taking laxatives and the patient's weight before surgery;

[0008] S2. Based on the scheduled data upload time, real-time acquisition of the patient's intraoperative weight change data and patient intraoperative information in the current time period;

[0009] S3, determining the fluid replacement rate based on the patient's preoperative information, the patient's intraoperative weight change data, and the patient's intraoperative information;

[0010] S4. Provide accurate fluid rehydration to patients based on their fluid rehydration speed;

[0011] S5, obtaining the patient's intraoperative weight change data and the patient's intraoperative information for the next time period;

[0012] S6. Based on the fluid infusion rule, determine the patient's intraoperative weight change data and the patient's intraoperative information in the next time period to obtain a corresponding determination control result.

[0013] Furthermore, the method of obtaining the patient's intraoperative weight change data and the patient's intraoperative information in the current time period based on the scheduled data upload time includes:

[0014] S2-1, obtaining the patient's initial intraoperative information in real time through a surgical monitoring device; wherein the patient's initial intraoperative information includes red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature;

[0015] S2-2, calculating a corresponding change rate or change value based on the red blood cell count, the hemoglobin cell concentration in the body, the blood pressure, the heart rate and the body temperature;

[0016] The patient's intraoperative information includes the red blood cell count, the hemoglobin cell concentration in the body, the blood pressure, the heart rate and the body temperature and their corresponding change rates or change values;

[0017] S2-3, using a measurement system to obtain a change in the patient's body fluids; wherein the change in the body fluids includes urine output and actual bleeding volume;

[0018] S2-4, based on the weighing device on the operating table, obtain the current time period in real time The intraoperative weight of all patients in the data set; each time period is 1 minute, which is the time for regularly uploading data; The value is 60. Both indicate time;

[0019] S2-5. Based on the current time period The weight of the patient during surgery is used to calculate the weight of the surgical instruments;

[0020] S2-6, obtaining the weight of surgically removed tissue;

[0021] S2-7, based on the weight of the surgical instrument, the urine output, the actual bleeding volume, the weight of the surgically removed tissue, and the time The corresponding patient's intraoperative weight is used to calculate the patient's intraoperative weight change data.

[0022] Furthermore, the measurement system includes a flushing fluid volume acquisition module, a body fluid collection device, a gauze collection device, a camera module, and a calculation module; the body fluid collection device includes a first body fluid collection device and a second body fluid collection device; the camera module includes a first camera and a second camera; wherein:

[0023] A flushing liquid volume collection module, used for collecting the flushing liquid volume using a pulse flushing instrument;

[0024] The first body fluid collection device is used to collect the fluid sucked by various suction devices during the operation and measure the corresponding fluid volume;

[0025] a second body fluid collection device, used for collecting urine of the patient and measuring urine output;

[0026] A gauze collection device is used to collect the gauze used in the surgical area of ​​the patient during surgery and measure the weight of the gauze;

[0027] a first camera, used to obtain first image information of the liquid in the first body fluid collection device;

[0028] A second camera is used to obtain a picture of each gauze entering the gauze collecting device to obtain second image information;

[0029] A calculation module is used to obtain the actual bleeding volume based on the first image information, the second image information, the flushing fluid volume and the liquid volume.

[0030] Further, the current time period The weight of the patient during surgery is used to calculate the weight of the surgical instruments, including:

[0031] The intraoperative weight data of the corresponding patient is collected every 10 ms by a weighing device and respectively used as clusters; each cluster is clustered by a clustering algorithm to obtain a corresponding clustering result;

[0032] A first threshold is set, and the absolute values ​​corresponding to the clustering results are judged respectively. The clustering results with absolute values ​​greater than or equal to the first threshold are determined as an increase or decrease in surgical instruments. The clusters corresponding to the current acquisition moment and the clusters corresponding to the previous acquisition moment are calculated to obtain the corresponding surgical instrument weights.

[0033] Furthermore, a sensor is provided on the outer side of the top of the second body fluid collection device to collect the inflow of urine and convert it into an electrical signal for uploading.

[0034] Furthermore, the step of obtaining the patient's intraoperative weight change data and the patient's intraoperative information in the next time period includes:

[0035] S5-1, using the same method as S2 to obtain the weight of surgical instruments, urine output, actual bleeding volume, surgically removed tissue weight and time of the next time period The corresponding patient’s intraoperative weight and patient’s intraoperative information;

[0036] S5-2, calculating the corresponding change rate or change value based on the red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature in the next time period;

[0037] S5-3, calculating the amount of fluid replenishment based on the fluid replenishment speed and the time for uploading the scheduled data;

[0038] S5-4, based on the amount of fluid replacement, the weight of the surgical instrument, the urine output, the actual amount of bleeding, the weight of the surgically removed tissue, and the time The corresponding patient's intraoperative weight is used to calculate the patient's intraoperative weight change data for the next time period.

[0039] Furthermore, the intraoperative weight change data and intraoperative information of the patient in the next time period are determined based on the fluid infusion rule to obtain a determination result, including:

[0040] S6-1, judging whether the red blood cell count is within the first threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-3; otherwise, judging the change rate or change value corresponding to the red blood cell count, and entering S6-2; wherein the initial value of M is zero;

[0041] S6-2, determining whether the change rate or change value corresponding to the red blood cell count is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1; wherein the initial values ​​of N and P are both zero, and entering S6-3;

[0042] S6-3, judging whether the hemoglobin cell concentration in the body is within the second threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-5; otherwise, judging the change rate or change value of the hemoglobin cell concentration in the body, and entering S6-4;

[0043] S6-4, determining whether the change rate or change value corresponding to the hemoglobin cell concentration in the body is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-5;

[0044] S6-5, judging whether the blood pressure is within the third threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-7; otherwise, judging the change rate or change value of the blood pressure, and entering S6-6;

[0045] S6-6, determining whether the change rate or change value corresponding to the blood pressure is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-7;

[0046] S6-7, judging whether the heart rate is within the fourth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-9; otherwise, judging the change rate or change value of the heart rate, and entering S6-8;

[0047] S6-8, determining whether the change rate or change value corresponding to the heart rate is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-9;

[0048] S6-9, judging whether the body temperature is within the fifth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-11; otherwise, judging the change rate or change value of the body temperature, and entering S6-10;

[0049] S6-10, determining whether the change rate or change value corresponding to the body temperature is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-11;

[0050] S6-11, judging whether the intraoperative weight change data of the patient in the next time period is within the sixth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1; otherwise, judging the absolute value of the intraoperative weight change data of the patient in the next time period, and entering S6-12;

[0051] S6-12, determining whether the absolute value of the patient's intraoperative weight change data in the next time period is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1;

[0052] S6-13. Determine the judgment result based on the M value, the N value and the P value; wherein the judgment result is to maintain the current fluid infusion speed, speed up the fluid infusion speed or reduce the fluid infusion speed.

[0053] Further, the determining the judgment result based on the M value, the N value and the P value includes:

[0054] like , then the judgment result is to maintain the current fluid infusion speed;

[0055] like and , then the judgment result is to speed up the fluid replenishment speed;

[0056] like and , the judgment result is to reduce the fluid infusion speed;

[0057] like and or , then manually set whether to maintain, speed up or slow down the fluid infusion rate.

[0058] A real-time control system for intraoperative fluid infusion based on patient weight changes, comprising a patient data acquisition module, a timing module, a patient intraoperative weight change calculation module, a patient intraoperative monitoring module, a fluid infusion module and a judgment control module; wherein:

[0059] Patient data collection module, used to obtain patient preoperative information;

[0060] Timing module, set the scheduled data upload time;

[0061] The patient's intraoperative weight change calculation module is used to obtain the patient's intraoperative weight change data in different time periods;

[0062] The patient intraoperative monitoring module is used to monitor the patient's intraoperative information in real time using a surgical monitoring device based on the patient's preoperative information, and obtain the patient's intraoperative information in different time periods;

[0063] A fluid infusion module, used to determine the fluid infusion speed based on the patient's preoperative information, the patient's intraoperative weight change data in the previous time period, and the patient's intraoperative information;

[0064] The judgment control module is used to judge the patient's intraoperative weight change data and the patient's intraoperative information in the next time period based on the fluid infusion rule to obtain the corresponding judgment control result.

[0065] The beneficial effects of the present invention are:

[0066] This method comprehensively considers the impact of multiple factors on the patient's intraoperative weight, and obtains a more accurate actual blood loss based on flushing fluid and body fluid collectors; based on the weight of surgical instruments, urine output, actual blood loss, surgically removed tissue weight, and the patient's intraoperative weight corresponding to the previous moment, the actual patient's intraoperative weight change data is calculated, effectively assisting doctors in making fluid infusion judgments, maintaining the patient's blood volume and internal environment balance, so that the patient's physical condition can support surgery; based on the fluid infusion rules, the patient's intraoperative weight change data and the patient's intraoperative information in the next time period are judged, and whether the patient's current fluid infusion speed is too fast or too slow is quickly judged, and timely feedback is sent to the monitoring screen to prevent surgical accidents caused by insufficient blood volume or imbalance of the internal environment in the patient's body, and help patients recover quickly after surgery;

[0067] The system has a simple structure and takes into account the impact of intraoperative flushing fluid and surgical instruments on the patient's weight. It provides a real-time control system for intraoperative fluid infusion, which assists doctors in monitoring the patient's weight changes at any time and formulating a corresponding fluid infusion speed, effectively maintaining the patient's vital signs and reducing the occurrence of medical accidents. BRIEF DESCRIPTION OF THE DRAWINGS

[0068] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0069] Figure 1 A flow chart of a method in an embodiment of the present invention;

[0070] Figure 2 It is a schematic diagram of the structure of the second body fluid collection device in an embodiment of the present invention; wherein, 1. a photoelectric sensor;

[0071] Figure 3 1 is a system structure diagram in an embodiment of the present invention. DETAILED DESCRIPTION

[0072] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. The components of the embodiments of the present invention generally described and shown in the drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents the selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making creative work belong to the scope of protection of the present invention.

[0073] See also Figure 1 This embodiment provides a method for real-time control of intraoperative precise fluid infusion based on patient weight changes, which includes:

[0074] S1. Obtain the patient's preoperative information and set a scheduled data upload time; wherein the patient's preoperative information includes preoperative weight, blood pressure, hemoglobin cell concentration in the body, red blood cell count, heart rate and body temperature; the preoperative weight includes the patient's weight after taking laxatives and the patient's weight before surgery;

[0075] Patients undergoing gynecological and intestinal surgery need to prepare their bowels the day before surgery, that is, take laxatives orally. Patients use diarrhea to cleanse their intestines. Although intravenous rehydration is routinely performed during bowel preparation, the degree of diarrhea varies from patient to patient. Some patients still experience insufficient body capacity due to insufficient rehydration, which lasts until the day of surgery. Therefore, the weight data of patients after taking laxatives orally is selected as the patient's preoperative data, so that the amount and ratio of rehydration can be more closely aligned with the actual needs of the patient when determining the amount and ratio of rehydration in the future.

[0076] S2. Based on the scheduled data upload time, real-time acquisition of the patient's intraoperative weight change data and patient intraoperative information in the current time period;

[0077] The scheduled data upload time is 1 minute. All the intraoperative change data and intraoperative information of the patients and other data are collected every 1 minute, and the data are processed by this method.

[0078] The method of obtaining the patient's intraoperative weight change data and the patient's intraoperative information in the current time period based on the scheduled data upload time includes:

[0079] S2-1. Obtain the patient's initial intraoperative information in real time through the surgical monitoring device; wherein, the patient's initial intraoperative information includes red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature; the surgical monitoring device is a prior art, so the technical content of this part will not be described in detail.

[0080] S2-2, calculating a corresponding change rate or change value based on the red blood cell count, the hemoglobin cell concentration in the body, the blood pressure, the heart rate and the body temperature;

[0081] The patient's intraoperative information includes the red blood cell count, the hemoglobin cell concentration in the body, the blood pressure, the heart rate and the body temperature and their corresponding change rates or change values, that is, the difference between the red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature in the previous time period (initial time) and the red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature in the current time period is calculated.

[0082] S2-3, using a measurement system to obtain a change in the patient's body fluids; wherein the change in the body fluids includes urine output and actual bleeding volume;

[0083] The measuring system comprises a flushing liquid volume acquisition module, a body fluid collection device, a gauze collection device, a camera module, and a calculation module; the body fluid collection device comprises a first body fluid collection device and a second body fluid collection device; the camera module comprises a first camera and a second camera; wherein:

[0084] A flushing liquid volume collection module, used for collecting the flushing liquid volume using a pulse flushing instrument;

[0085] The first body fluid collection device is used to collect the fluid sucked by various suction devices during the operation and measure the corresponding fluid volume;

[0086] a second body fluid collection device, used for collecting urine of the patient and measuring urine output;

[0087] A gauze collection device is used to collect the gauze used in the surgical area of ​​the patient during surgery and measure the weight of the gauze;

[0088] a first camera, used to obtain first image information of the liquid in the first body fluid collection device;

[0089] A second camera is used to obtain a picture of each gauze entering the gauze collecting device to obtain second image information;

[0090] The calculation module is used to obtain the actual bleeding volume based on the first image information, the second image information, the flushing fluid volume and the liquid volume. The calculation module is divided into an intraoperative bleeding volume calculation module and an actual bleeding volume calculation module.

[0091] The first body fluid collection device, gauze collection device, first camera, second camera and intraoperative bleeding volume calculation module of the measuring system use the same equipment as the body fluid collection device, gauze collection device, first camera and second camera in the intraoperative bleeding volume measurement system (CN118177747B) to calculate the liquid volume, that is, the total intraoperative bleeding volume, so as not to describe in detail the data processing process or processing method corresponding to the first body fluid collection device, gauze collection device, first camera, second camera and intraoperative bleeding volume calculation module of the measuring system.

[0092] In the actual bleeding volume calculation module, according to the formula:

[0093] ;

[0094] Get the actual amount of bleeding ;in, Indicates the total intraoperative blood loss. Indicates the volume of the flushing fluid.

[0095] like Figure 2 As shown, the second body fluid collection device is a urine collection bag made of transparent material, and a photoelectric sensor 1 is arranged on the outer side of the top to collect the inflow of urine and convert it into an electrical signal for uploading. The electrical signal obtained by the photoelectric sensor 1 is converted to obtain the corresponding urine output. This process is a prior art and will not be described in detail.

[0096] During surgery, in order to keep the incision visible, flushing fluid is used to clean the blood around the incision, keep the surgeon's field of vision clear, and prevent medical accidents and prolonged surgery due to unclear field of vision. Therefore, the blood collected by the body fluid collection device contains not only blood but also a part of flushing fluid. Based on the intraoperative bleeding volume measurement system (CN118177747B), this method takes the issue of flushing fluid into consideration, so that the total intraoperative bleeding volume is closer to the actual bleeding volume of the patient, and effectively assists the surgeon and anesthesiologist in determining whether blood transfusion is needed, which component is needed, and how much blood transfusion is needed based on the intraoperative blood loss situation.

[0097] S2-4, based on the weighing device on the operating table, obtain the current time period in real time The intraoperative weight of all patients in the data set; each time period is 1 minute, which is the time for scheduled data upload; The value is 60. Both indicate time;

[0098] S2-5. Based on the current time period The weight of the patient during surgery is used to calculate the weight of the surgical instruments;

[0099] Based on the current time period The weight of the patient during surgery is used to calculate the weight of the surgical instruments, including:

[0100] The intraoperative weight data of the corresponding patient is collected every 10 ms by a weighing device and respectively used as clusters; each cluster is clustered by a clustering algorithm to obtain a corresponding clustering result;

[0101] A first threshold is set, and the absolute values ​​corresponding to the clustering results are judged respectively, and the clustering results with absolute values ​​greater than or equal to the first threshold are judged as an increase or decrease of surgical instruments, and the cluster corresponding to the current acquisition moment and the cluster corresponding to the previous acquisition moment are calculated to obtain the corresponding surgical instrument weight. The setting of the first threshold is related to the type of surgery, so the corresponding first threshold is determined based on the type of surgery and actual needs.

[0102] S2-6, obtaining the weight of surgically removed tissue; a tissue weighing device is placed next to the operating table, and the doctor places the removed tissue on the tissue weighing device for weighing, and uploads the corresponding weighing information (weight of surgically removed tissue) after weighing. The tissue weighing device can be a weighing device with a transmission function in the prior art.

[0103] S2-7, based on the weight of the surgical instrument, the urine output, the actual bleeding volume, the weight of the surgically removed tissue, and the time The corresponding patient's intraoperative weight is used to calculate the patient's intraoperative weight change data.

[0104] Before the operation officially begins, medical staff will lay sterile treatment towels around the surgical site to create a sterile environment, so the patient's pre-operative weight cannot be used to calculate the patient's weight change during the operation. Instead, at the beginning of the operation, the patient is weighed using the weighing device on the operating table, and the patient's weight at this time is used as the patient's initial weight during the operation.

[0105] The weight of the surgical instrument, the urine output, the actual bleeding volume, the weight of the surgically removed tissue, and the time The units of the corresponding patients' intraoperative weight are unified to facilitate the subsequent direct calculation of the patients' intraoperative weight change data.

[0106] The formula for the patient's intraoperative weight change data is:

[0107] ;

[0108] in, Indicates the current time period The intraoperative weight change of the patient, that is, the intraoperative weight change data of the patient; Indicates the current time period The patient's intraoperative weight; Indicates the previous time period The patient's intraoperative weight, When is 1, is the patient's initial weight during surgery; Indicates the weight of surgical instruments; Indicates the current time period The actual amount of bleeding, i.e. ; Indicates the current time period The amount of urine output; Indicates the current time period The weight of surgically removed tissue. At the initial moment, the patient did not receive any fluid replacement, so the amount of fluid replacement did not need to be considered.

[0109] S3, determining the fluid replacement rate based on the patient's preoperative information, the patient's intraoperative weight change data, and the patient's intraoperative information;

[0110] The fluid infusion rate can be determined manually, or a model can be used to predict the patient's preoperative information, the patient's intraoperative weight change data, and the patient's intraoperative information to obtain a predicted value of the fluid infusion rate. Medical staff can quickly determine the final fluid infusion rate based on the predicted value of the fluid infusion rate.

[0111] The doctor confirms the amount and ratio of fluid replacement based on the patient's preoperative information, the patient's intraoperative weight change data, and the patient's intraoperative information. Or the doctor confirms the ratio of fluid replacement based on the patient's preoperative information, the patient's intraoperative weight change data, and the patient's intraoperative information, and then uses the algorithm or model to calculate the corresponding initial fluid replacement volume; the initial fluid replacement volume is manually checked to obtain the fluid replacement volume. Among them, the algorithm or model can select pulse neural network, machine learning and logistic regression model, Python and other methods. In general, crystalloids and colloids are used for fluid replacement, and the corresponding fluid replacement ratio is: crystalloid: colloid = 2:1.

[0112] The model can be a linear regression model, a random forest model, etc. The corresponding process is:

[0113] Constructing a fluid infusion speed determination model; the fluid infusion speed determination model includes two parallel random forest models, namely a first random module and a second random module;

[0114] The correlation between the amount of fluid replacement, the ratio of fluid replacement and the surgical information, the patient's intraoperative weight change data, body temperature, heart rate, blood pressure, red blood cell count, hemoglobin cell concentration in the body and the actual amount of bleeding is calculated respectively; the surgical information includes age, gender and surgical type; the method for calculating the correlation is the existing technology;

[0115] According to the magnitude of the correlation between the amount of fluid replacement, the ratio of fluid replacement, and the surgical information, the patient's intraoperative weight change data, body temperature, heart rate, blood pressure, red blood cell count, hemoglobin cell concentration in the body, and the actual amount of bleeding, the data corresponding to the greater correlation with the amount of fluid replacement and the amount of fluid replacement are selected as the first data, and the data corresponding to the greater correlation with the ratio of fluid replacement and the amount of fluid replacement are selected as the second data;

[0116] Inputting the first data and the second data into the first random module and the second random module respectively, and outputting the corresponding initial fluid replenishment speeds respectively;

[0117] According to the formula:

[0118] ;

[0119] Get the final fluid filling rate ;in, Indicates the total number of input data types of the first random module; Indicates The weight of the input data type of the first random module; Indicates The correlation between the input data type of the first random module and the amount of fluid replacement; , They represent the initial fluid replenishment rates output by the two random forest models respectively; Represents the total number of input data types of the second random module; Indicates The weight of the input data type of the second random module; Indicates The correlation between the input data type of the second random module and the fluid replacement ratio; Indicates the adjustment coefficient. The types of surgery are divided into small, medium, large and special types. Special types include abdominal types. When the types of surgery are small, medium, large and special types, the adjustment coefficient The corresponding values ​​are 0.25, 0.5, 0.75 and 1.

[0120] S4. Provide accurate fluid rehydration to patients based on their fluid rehydration speed;

[0121] S5, obtaining the patient's intraoperative weight change data and the patient's intraoperative information for the next time period;

[0122] The step of obtaining the patient's intraoperative weight change data and the patient's intraoperative information in the next time period includes:

[0123] S5-1, using the same method as S2 to obtain the weight of surgical instruments, urine output, actual bleeding volume, surgically removed tissue weight and time of the next time period The corresponding patient’s intraoperative weight and patient’s intraoperative information;

[0124] S5-2, calculating the corresponding change rate or change value based on the red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature in the next time period;

[0125] S5-3, based on the fluid replenishment speed and the time for uploading data at a scheduled time, calculating the amount of fluid replenishment, that is, the product of the fluid replenishment speed and the time for uploading data at a scheduled time is the amount of fluid replenishment;

[0126] S5-3, based on the amount of fluid replacement, the weight of the surgical instrument, the urine output, the actual amount of bleeding, the weight of the surgically removed tissue, and the time The corresponding intraoperative weight of the patient is used to calculate the intraoperative weight change data of the patient in the next time period. The corresponding formula is:

[0127] ;

[0128] in, Indicates the next time period Intraoperative weight change data of patients Indicates the next time period The patient's intraoperative weight, Indicates the next time period The amount of fluid replacement, Indicates the next time period The weight of surgical instruments, Indicates the next time period The actual amount of bleeding, Indicates the next time period The amount of urine output, Indicates the next time period Weight of surgically removed tissue.

[0129] S6. Based on the fluid infusion rule, determine the patient's intraoperative weight change data and the patient's intraoperative information in the next time period to obtain a corresponding determination control result.

[0130] The method of determining the patient's intraoperative weight change data and the patient's intraoperative information in the next time period based on the fluid infusion rule to obtain a determination result includes:

[0131] S6-1, judging whether the red blood cell count is within the first threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-3; otherwise, judging the change rate or change value corresponding to the red blood cell count, and entering S6-2; wherein the initial value of M is zero;

[0132] S6-2, determining whether the change rate or change value corresponding to the red blood cell count is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1; wherein the initial values ​​of N and P are both zero, and entering S6-3;

[0133] S6-3, judging whether the hemoglobin cell concentration in the body is within the second threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-5; otherwise, judging the change rate or change value of the hemoglobin cell concentration in the body, and entering S6-4;

[0134] S6-4, determining whether the change rate or change value corresponding to the hemoglobin cell concentration in the body is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-5;

[0135] S6-5, judging whether the blood pressure is within the third threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-7; otherwise, judging the change rate or change value of the blood pressure, and entering S6-6;

[0136] S6-6, determining whether the change rate or change value corresponding to the blood pressure is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-7;

[0137] S6-7, judging whether the heart rate is within the fourth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-9; otherwise, judging the change rate or change value of the heart rate, and entering S6-8;

[0138] S6-8, determining whether the change rate or change value corresponding to the heart rate is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-9;

[0139] S6-9, judging whether the body temperature is within the fifth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-11; otherwise, judging the change rate or change value of the body temperature, and entering S6-10;

[0140] S6-10, determining whether the change rate or change value corresponding to the body temperature is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-11;

[0141] S6-11, judging whether the intraoperative weight change data of the patient in the next time period is within the sixth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1; otherwise, judging the absolute value of the intraoperative weight change data of the patient in the next time period, and entering S6-12;

[0142] S6-12, determining whether the absolute value of the patient's intraoperative weight change data in the next time period is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1;

[0143] S6-13. Determine the judgment result based on the M value, the N value and the P value; wherein the judgment result is to maintain the current fluid infusion speed, speed up the fluid infusion speed or reduce the fluid infusion speed.

[0144] Among them, the first threshold range to the sixth threshold range are formulated according to actual needs.

[0145] The determining the judgment result based on the M value, the N value and the P value includes:

[0146] like , then the judgment result is to maintain the current fluid infusion speed;

[0147] like and , then the judgment result is to speed up the fluid replenishment speed;

[0148] like and , the judgment result is to reduce the fluid infusion speed;

[0149] like and or , then manually set whether to maintain, speed up or slow down the fluid infusion rate.

[0150] During the entire fluid infusion process, S2 to S6 are repeated until the patient no longer needs fluid infusion. The judgment control results, red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature and their corresponding change rates or change values ​​are all displayed on the anesthesiologist's monitoring display screen. When the anesthesiologist sees the display "need for fluid infusion and fluid infusion speed" and the judgment control results, the doctor is notified to make the final determination of the fluid infusion speed and whether to execute the judgment control results. Based on the judgment control results, the increase or decrease in the fluid infusion speed is determined, and a nurse or assistant doctor is arranged to implement it.

[0151] This method comprehensively considers the impact of multiple factors on the patient's intraoperative weight, and obtains a more accurate actual blood loss based on flushing fluid and body fluid collectors; based on the weight of surgical instruments, urine output, actual blood loss, surgically removed tissue weight, and the patient's intraoperative weight corresponding to the previous moment, the actual patient's intraoperative weight change data is calculated, effectively assisting doctors in making fluid replacement judgments, maintaining the patient's blood volume and internal environment balance, so that the patient's physical condition can support surgery; based on the fluid replacement rules, the patient's intraoperative weight change data and the patient's intraoperative information in the next time period are judged, and the patient's current fluid replacement speed is quickly judged whether it is too fast or too slow, and timely feedback is sent to the monitoring screen to prevent surgical accidents caused by insufficient blood volume or imbalance of the internal environment in the patient's body, and to help patients recover quickly after surgery.

[0152] like Figure 3 As shown, a real-time control system for intraoperative fluid infusion based on patient weight changes includes a patient data acquisition module, a timing module, a patient intraoperative weight change calculation module, a patient intraoperative monitoring module, a fluid infusion module and a judgment control module; wherein:

[0153] Patient data collection module, used to obtain patient preoperative information;

[0154] Timing module, set the scheduled data upload time;

[0155] The patient's intraoperative weight change calculation module is used to obtain the patient's intraoperative weight change data in different time periods;

[0156] The patient intraoperative monitoring module is used to monitor the patient's intraoperative information in real time using a surgical monitoring device based on the patient's preoperative information, and obtain the patient's intraoperative information in different time periods;

[0157] A fluid infusion module, used to determine the fluid infusion speed based on the patient's preoperative information, the patient's intraoperative weight change data in the previous time period, and the patient's intraoperative information;

[0158] The judgment control module is used to judge the patient's intraoperative weight change data and the patient's intraoperative information in the next time period based on the fluid infusion rule to obtain the corresponding judgment control result.

[0159] The system has a simple structure and takes into account the impact of intraoperative flushing fluid and surgical instruments on the patient's weight. It provides a real-time control system for intraoperative fluid infusion, which assists doctors in monitoring the patient's weight changes at any time and formulating a corresponding fluid infusion speed, effectively maintaining the patient's vital signs and reducing the occurrence of medical accidents.

[0160] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A method for real-time control of intraoperative precise fluid infusion based on patient weight changes, characterized in that: include: S1. Obtain the patient's preoperative information and set a scheduled data upload time; wherein the patient's preoperative information includes preoperative weight, blood pressure, hemoglobin cell concentration in the body, red blood cell count, heart rate and body temperature; the preoperative weight includes the patient's weight after taking laxatives and the patient's weight before surgery; S2. Based on the scheduled data upload time, real-time acquisition of the patient's intraoperative weight change data and patient intraoperative information in the current time period; S3, determining the fluid replacement rate based on the patient's preoperative information, the patient's intraoperative weight change data, and the patient's intraoperative information; S4. Provide accurate fluid rehydration to patients based on their fluid rehydration speed; S5, obtaining the patient's intraoperative weight change data and the patient's intraoperative information for the next time period; S6. Based on the fluid infusion rule, determine the patient's intraoperative weight change data and the patient's intraoperative information in the next time period, and obtain a corresponding determination control result; The method of obtaining the patient's intraoperative weight change data and the patient's intraoperative information in the current time period based on the scheduled data upload time includes: S2-1, obtaining the patient's initial intraoperative information in real time through a surgical monitoring device; wherein the patient's initial intraoperative information includes red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature; S2-2, calculating a corresponding change rate or change value based on the red blood cell count, the hemoglobin cell concentration in the body, the blood pressure, the heart rate and the body temperature; The patient's intraoperative information includes the red blood cell count, the hemoglobin cell concentration in the body, the blood pressure, the heart rate and the body temperature and their corresponding change rates or change values; S2-3, using a measurement system to obtain a change in the patient's body fluids; wherein the change in the body fluids includes urine output and actual bleeding volume; S2-4, based on the weighing device on the operating table, obtain the current time period in real time The intraoperative weight of all patients in the data set; each time period is 1 minute, which is the time for regularly uploading data; The value is 60. Both indicate time; S2-5. Based on the current time period The weight of the patient during surgery is used to calculate the weight of the surgical instruments; S2-6, obtaining the weight of surgically removed tissue; S2-7, based on the weight of the surgical instrument, the urine output, the actual bleeding volume, the weight of the surgically removed tissue, and the time The corresponding patient's intraoperative weight is used to calculate the patient's intraoperative weight change data.

2. The method for real-time control of intraoperative precise fluid infusion based on patient weight changes according to claim 1, characterized in that: The measuring system comprises a flushing fluid volume acquisition module, a body fluid collection device, a gauze collection device, a camera module, and a calculation module; the body fluid collection device comprises a first body fluid collection device and a second body fluid collection device; The camera module includes a first camera and a second camera; wherein: A flushing liquid volume collection module, used for collecting the flushing liquid volume using a pulse flushing instrument; The first body fluid collection device is used to collect the fluid sucked by various suction devices during the operation and measure the corresponding fluid volume; a second body fluid collection device, used for collecting urine of the patient and measuring urine output; A gauze collection device is used to collect the gauze used in the surgical area of ​​the patient during surgery and measure the weight of the gauze; a first camera, used to obtain first image information of the liquid in the first body fluid collection device; A second camera is used to obtain a picture of each gauze entering the gauze collecting device to obtain second image information; A calculation module is used to obtain the actual bleeding volume based on the first image information, the second image information, the flushing fluid volume and the liquid volume.

3. The method for real-time control of intraoperative precise fluid infusion based on patient weight changes according to claim 1, characterized in that: Based on the current time period The weight of the patient during surgery is used to calculate the weight of the surgical instruments, including: The intraoperative weight data of the corresponding patient is collected every 10 ms by a weighing device and respectively used as clusters; each cluster is clustered by a clustering algorithm to obtain a corresponding clustering result; A first threshold is set, and the absolute values ​​corresponding to the clustering results are judged respectively. The clustering results with absolute values ​​greater than or equal to the first threshold are determined as an increase or decrease in surgical instruments. The clusters corresponding to the current acquisition moment and the clusters corresponding to the previous acquisition moment are calculated to obtain the corresponding surgical instrument weights.

4. The method for real-time control of intraoperative precise fluid infusion based on patient weight changes according to claim 2, characterized in that: A sensor is arranged on the outer side of the top of the second body fluid collection device to collect the inflow of urine and convert it into an electrical signal for uploading.

5. The method for real-time control of intraoperative precise fluid infusion based on patient weight changes according to claim 1, characterized in that: The step of obtaining the patient's intraoperative weight change data and the patient's intraoperative information in the next time period includes: S5-1, using the same method as S2 to obtain the weight of surgical instruments, urine output, actual bleeding volume, surgically removed tissue weight and time of the next time period The corresponding patient’s intraoperative weight and patient’s intraoperative information; S5-2, calculating the corresponding change rate or change value based on the red blood cell count, hemoglobin cell concentration in the body, blood pressure, heart rate and body temperature in the next time period; S5-3, calculating the amount of fluid replenishment based on the fluid replenishment speed and the time for uploading the scheduled data; S5-4, based on the amount of fluid replacement, the weight of the surgical instrument, the urine output, the actual amount of bleeding, the weight of the surgically removed tissue, and the time The corresponding patient's intraoperative weight is used to calculate the patient's intraoperative weight change data for the next time period.

6. The method for real-time control of intraoperative precise fluid infusion based on patient weight changes according to claim 5, characterized in that: The method of determining the patient's intraoperative weight change data and the patient's intraoperative information in the next time period based on the fluid infusion rule to obtain a determination result includes: S6-1, judging whether the red blood cell count is within the first threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-3; otherwise, judging the change rate or change value corresponding to the red blood cell count, and entering S6-2; wherein the initial value of M is zero; S6-2, determining whether the change rate or change value corresponding to the red blood cell count is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1; wherein the initial values ​​of N and P are both zero, and entering S6-3; S6-3, judging whether the hemoglobin cell concentration in the body is within the second threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-5; otherwise, judging the change rate or change value of the hemoglobin cell concentration in the body, and entering S6-4; S6-4, determining whether the change rate or change value corresponding to the hemoglobin cell concentration in the body is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-5; S6-5, judging whether the blood pressure is within the third threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-7; otherwise, judging the change rate or change value of the blood pressure, and entering S6-6; S6-6, determining whether the change rate or change value corresponding to the blood pressure is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-7; S6-7, judging whether the heart rate is within the fourth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-9; otherwise, judging the change rate or change value of the heart rate, and entering S6-8; S6-8, determining whether the change rate or change value corresponding to the heart rate is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-9; S6-9, judging whether the body temperature is within the fifth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1, and entering S6-11; otherwise, judging the change rate or change value of the body temperature, and entering S6-10; S6-10, determining whether the change rate or change value corresponding to the body temperature is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1, and entering S6-11; S6-11, judging whether the intraoperative weight change data of the patient in the next time period is within the sixth threshold range; if so, maintaining the current fluid infusion rate, and increasing the M value by 1; otherwise, judging the absolute value of the intraoperative weight change data of the patient in the next time period, and entering S6-12; S6-12, determining whether the absolute value of the patient's intraoperative weight change data in the next time period is less than 0; if so, determining that the patient's fluid infusion amount is low, the fluid infusion speed needs to be accelerated, and the N value is increased by 1; otherwise, determining that the patient's fluid infusion amount is high, the fluid infusion speed needs to be reduced, and the P value is increased by 1; S6-13. Determine the judgment result based on the M value, the N value and the P value; wherein the judgment result is to maintain the current fluid infusion speed, speed up the fluid infusion speed or reduce the fluid infusion speed.

7. The method for real-time control of intraoperative precise fluid infusion based on patient weight changes according to claim 6, characterized in that: The determining the judgment result based on the M value, the N value and the P value includes: like , then the judgment result is to maintain the current fluid infusion speed; like and , then the judgment result is to speed up the fluid replenishment speed; like and , the judgment result is to reduce the fluid infusion speed; like and or , then manually set whether to maintain, speed up or slow down the fluid infusion rate.

8. A real-time control system for intraoperative fluid infusion based on patient weight changes, used to implement the real-time control method for intraoperative precise fluid infusion based on patient weight changes according to any one of claims 1 to 7, characterized in that: It includes a patient data acquisition module, a timing module, a patient intraoperative weight change calculation module, a patient intraoperative monitoring module, a fluid infusion module and a judgment control module; wherein: Patient data collection module, used to obtain patient preoperative information; Timing module, set the scheduled data upload time; The patient's intraoperative weight change calculation module is used to obtain the patient's intraoperative weight change data in different time periods; The patient intraoperative monitoring module is used to monitor the patient's intraoperative information in real time using a surgical monitoring device based on the patient's preoperative information, and obtain the patient's intraoperative information in different time periods; A fluid infusion module, used to determine the fluid infusion speed based on the patient's preoperative information, the patient's intraoperative weight change data in the previous time period, and the patient's intraoperative information; The judgment control module is used to judge the patient's intraoperative weight change data and the patient's intraoperative information in the next time period based on the fluid infusion rule to obtain the corresponding judgment control result.

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