Major specimen preservation method and preservation equipment

Abstract

The invention belongs to the technical field of human body preservation, and particularly relates to a general specimen preservation method and preservation equipment. The general specimen preservation method comprises the following steps that a general specimen is placed in preservation liquid of preservation equipment, the preservation liquid at the bottom is intermittently or continuously sucked to the position above the liquid level of the preservation liquid for spraying or mist spraying backflow, and the preservation liquid comprises sodium chloride, a bactericide, a preservative and water. Sodium chloride, a sterilizing agent and a preservative are added into the preserving fluid, the sterilizing agent and the preservative have the sterilizing and preservative effects, liquid at the bottom of the preserving fluid is sucked to the position above the liquid level to be sprayed or sprayed, and the concentration of the sodium chloride and the sterilizing agent on the liquid level of the preserving fluid is higher than that of the liquid at the bottom; a sodium chloride crystal film even appears on the liquid surface of the preservation liquid, so that the sterilization effect of a gas-liquid contact interface is greatly improved, the breeding of microorganisms such as bacteria and fungi in the long-time preservation process of the general specimen is improved, the preservation time of the general specimen is prolonged, and the preservation effect of the general specimen is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of human body preservation, and in particular to a method and equipment for preserving a gross specimen. Background Art

[0002] Gross specimens are important teaching materials for the experimental teaching of anatomy and pathology in medical majors. Through comprehensive and detailed observation of specimens, we can have a deeper understanding of anatomy and pathology knowledge, especially in the teaching, medical treatment and scientific research of clinical medicine and surgeons. Gross specimens have strict requirements and clear purposes in selection, and they need to undergo necessary technical processing to make the morphological characteristics more prominent and better show the full picture of the occurrence and development of the disease, so as to give full play to their important role in clinical pathology teaching and scientific research.

[0003] The processing process after receiving the body is as follows: (1) disinfection; (2) perfusion of preservative solution; (3) storage after perfusion. There are two methods for preserving gross specimens. One is to place the perfused body in a 4-7℃ storage cabinet, and the other is to directly place the body in a 5% formalin solution for preservation. Considering the stability, long-term, and economical nature of preservation, as well as the convenience of using gross specimens, direct preservation in a 5% formalin solution has become the selected gross preservation method in medical research and teaching.

[0004] In recent years, some environmentally friendly cadaver specimen preservation solutions and preservation methods have emerged. A Chinese patent application with application publication number CN101473813A, which was filed on July 8, 2009, discloses a composition for preserving cadaver specimens and a preparation method thereof. The composition comprises an antiseptic and mildew-proof active ingredient, an osmotic regulator, a moisturizer and a quaternary ammonium salt compound. The osmotic regulator comprises nitrate, sulfate and sodium chloride, the moisturizer comprises ethylene glycol, propylene glycol and diethylene glycol, etc., and the antiseptic and mildew-proof active ingredient is diacetate. The preservation solution can effectively solve the problems of cadaver preservation, mildew-proof and preservation when used for preserving animal or human cadavers. The preservation solution is characterized by long antiseptic and mildew-proof time, good effect, no formaldehyde, and safe and non-toxic.

[0005] However, in the process of long-term preservation of gross specimens, preventing the growth of microorganisms such as bacteria and fungi is also of paramount importance. Improving the formula of the preservation fluid alone cannot solve the problem of frequent growth of bacteria and other microorganisms during long-term preservation of gross specimens. How to improve the antibacterial, antibacterial and bactericidal effects of corpses during long-term preservation, and thereby extend the preservation time and preservation effect of gross specimens, is still a problem in the preservation of gross specimens. Summary of the invention

[0006] The purpose of the present invention is to provide a method for preserving gross specimens, so as to solve the problem that the preservation effect of gross specimens is poor due to the growth of microorganisms such as bacteria and fungi during long-term preservation.

[0007] The second object of the present invention is to provide a preservation device using the above-mentioned gross specimen preservation method, so as to solve the problem of poor preservation effect of gross specimens due to the growth of microorganisms such as bacteria and fungi during long-term preservation.

[0008] In order to solve the above technical problems, the technical solution of the method for preserving gross specimens of the present invention is: A method for preserving a gross specimen comprises the following steps: placing the gross specimen in a preservation solution of a preservation device, intermittently or continuously pumping the preservation solution at the bottom to the top of the preservation solution surface for spraying or spray reflux, wherein the preservation solution comprises sodium chloride, a bactericide, a preservative and water.

[0009] The present invention is an improvement on the prior art, and provides a method for preserving gross specimens. The method comprises the following steps: adding sodium chloride, a bactericide and a preservative into a water-based preservative solution, wherein the bactericide can sterilize microorganisms such as bacteria and fungi that grow during the preservation of the gross specimens, and the preservative can preserve the gross specimens; and the preservative solution at the bottom is sucked to the top of the liquid surface for spraying. After the preservative solution is sprayed or atomized, the solvent water of the preservative solution evaporates, and the sodium chloride and the bactericide in the preservative solution fall back to the liquid surface of the preservative solution, so that the concentrations of the sodium chloride and the bactericide at the liquid surface of the preservative solution are higher than those at the bottom of the liquid, and dynamic stratification of the preservative solution is achieved. A sodium chloride crystal film may even appear on the liquid surface of the preservative solution, which greatly improves the bactericidal effect of the gas-liquid contact interface, thereby improving the growth of microorganisms such as bacteria during the long-term preservation of the gross specimens, improving the antibacterial, antibacterial and bactericidal effects during the long-term preservation of the gross specimens, and thereby prolonging the preservation time of the gross specimens and improving the preservation effect.

[0010] In order to further improve the sterilization effect of the gas-liquid interface, preferably, the mass fraction of the sodium chloride in the preservation solution is 2-15%.

[0011] In order to further improve the sterilization effect of the preservation solution, preferably, the preservation solution sprayed or sprayed backflowed is sterilized by ultraviolet light above the liquid surface of the preservation solution. Ultraviolet light sterilization can sterilize the preservation solution and the gas space above the preservation device.

[0012] In order to further synergistically improve the sterilization effect on microorganisms in the preservation solution, preferably, the duration of spraying or misting is 4 to 24 hours per day.

[0013] Since formaldehyde has a strong pungent odor, it can cause damage to multiple organs and systems, seriously endangering the health of people who come into contact with it. In order to further improve the environmental protection and safety of the preservation method, preferably, the preservation device is water-sealed, and when the preservative contains formaldehyde, the aqueous solution used for the water seal contains a formaldehyde remover. The formaldehyde remover is potassium permanganate. When the preservative includes ethanol, since ethanol is easy to explode after mixing with air, the preservation device is water-sealed, which can effectively absorb the volatilized ethanol and prevent it from diffusing into the outside air, which can further improve the environmental protection and safety of the preservation method.

[0014] The technical solution of the gross specimen preservation device of the present invention is: A gross specimen preservation device comprises a liquid storage tank for containing preservation liquid and a reflux device, wherein the reflux device comprises a circulation pipeline, wherein the circulation pipeline has a liquid inlet and a liquid outlet, wherein the liquid inlet is located on the side wall of the liquid storage tank close to the bottom of the tank or the bottom wall of the tank, and the liquid outlet is provided with a spray device or a mist device, wherein the spray device or the mist device is located above the liquid level of the preservation liquid.

[0015] The preservation device provided by the present invention is provided with a liquid storage tank and a reflux device, and the liquid at the bottom of the preservation liquid is sucked to the reflux device through the liquid inlet of the circulation pipeline, and then the preservation liquid at the bottom is sucked to the top of the liquid surface for spraying or spraying through the spray device or the spray device at the liquid outlet of the circulation pipeline. With the help of a specific preservation liquid, the concentration of sodium chloride and bactericide in the liquid surface part of the preservation liquid can be higher than that in the bottom liquid, so that the dynamic stratification of the preservation liquid is realized, and even a sodium chloride crystal film will appear on the liquid surface of the preservation liquid, which greatly improves the bactericidal effect of the gas-liquid contact interface, thereby improving the growth of bacteria and other microorganisms during the long-term preservation of the gross body, improving the antibacterial, antibacterial and bactericidal effects during the long-term preservation of the gross body, and thus prolonging the preservation time and preservation effect of the gross specimen.

[0016] In order to further improve the uniformity of the spray, preferably, the spray device or the spraying device comprises an annular pipe arranged along the inner wall of the liquid storage tank, and the annular pipe is provided with a nozzle for spraying or spraying. The operation time of the spray device or the spraying device is 4 to 24 hours per day.

[0017] In order to further improve the spray efficiency, preferably, the angle between the direction of the spray head and the liquid surface of the preservation solution is 30°~60°.

[0018] In order to further improve the sterilization effect, preferably, the liquid storage tank is provided with an ultraviolet sterilization device on the side wall above the liquid level of the preservation liquid and below the spray device or the spray device. When the spray device or the spray device is in operation, the ultraviolet sterilization device is turned on synchronously.

[0019] In order to further improve the sealing performance of the storage device, preferably, a water sealing groove is provided at the opening of the liquid storage tank, and the storage device has a sealing cover that is sealed with the water sealing groove. It can be understood that the aqueous solution used for water sealing can be pure water or an aqueous solution containing a certain substance. When the storage liquid contains formaldehyde, the aqueous solution used for water sealing is an aqueous solution containing a formaldehyde scavenger, which can absorb the volatilized formaldehyde. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the structure of the preservation device using the method for preserving a gross specimen of the present invention; In the attached drawings: 1. liquid storage tank; 11. water sealing groove; 12. annular inner wall; 13. annular outer wall; 2. reflux device; 21. inflow valve; 22. outflow valve; 23. circulation pipeline; 24. booster pump; 25. filter; 3. spray device; 31. annular pipeline; 4. sealing cover; 5. ultraviolet sterilization device. DETAILED DESCRIPTION

[0021] The technical concept of the method for preserving gross specimens provided by the present invention is as follows: Among the existing methods for preserving gross specimens, most are to immerse the gross specimens in a preservation solution, such as a formalin solution, or to adjust the preservation solution formula to thereby improve the preservation time and preservation effect of the gross specimens.

[0022] The present invention innovatively adopts a method of combining the formula of the preservation solution and the concentration difference of the preservation solution. By adding sodium chloride, a bactericide and a preservative into the water-based preservation solution, the bactericide can sterilize the microorganisms such as bacteria and fungi that grow during the preservation of the gross specimens, and the preservative can preserve the gross specimens; and by sucking the liquid at the bottom of the preservation solution to the top of the liquid surface for spraying or atomizing, after the preservation solution is sprayed or atomized, the solvent of the preservation solution evaporates, and the sodium chloride and the bactericide in the preservation solution will fall back to the liquid surface of the preservation solution, resulting in a higher concentration of sodium chloride and the bactericide in the liquid surface of the preservation solution than in the liquid at the bottom, thereby realizing dynamic stratification of the preservation solution, and even a sodium chloride crystal film will appear on the liquid surface of the preservation solution, which greatly improves the bactericidal effect of the gas-liquid contact interface, thereby improving the growth of microorganisms such as bacteria during the long-term preservation of the gross specimens, improving the antibacterial, antibacterial and bactericidal effects during the long-term preservation of the gross specimens, thereby extending the preservation time of the gross specimens and improving the preservation effect.

[0023] In a specific embodiment, the fungicide is a broad-spectrum fungicide, and the spectrum fungicide includes triadimefon, meconium, polyastatin, flusilazole, pyrimidine nucleoside antibiotics, myclobutanil, thiophanate-methyl, pyrimidine phthalate, azoxystrobin, difenoconazole, tebuconazole, propiconazole, fluopicolide, penconazole, etc.

[0024] In a specific embodiment, the preservation solution is composed of water, sodium chloride, a bactericide and a preservative, and the preservative is selected from one or two of formaldehyde and ethanol; at this time, when the preservation solution at the bottom is sucked to the top of the preservation solution surface for spraying or spray reflux, the formaldehyde aqueous solution, ethanol aqueous solution or formaldehyde ethanol mixed aqueous solution will evaporate, and the sodium chloride in the preservation solution will fall back to the preservation solution surface, so that the sodium chloride concentration on the preservation solution surface is higher than that at the bottom of the preservation solution; compared with the volatilization of solvent water, the formaldehyde aqueous solution, ethanol aqueous solution or formaldehyde ethanol mixed aqueous solution is easier to volatilize.

[0025] In a specific embodiment, the preservation solution consists of water and a mass fraction of 2-15% sodium chloride, 0.25-15% bactericide, and 3.5-35% preservative; when the preservative includes formaldehyde, the formaldehyde concentration is 2-10%, specifically, the preservation solution consists of water and a mass fraction of 2-15% sodium chloride, 0.25-1.5% bactericide, and 2-10% formaldehyde; when the preservative includes ethanol, the ethanol concentration is 10-35%, and the preservation solution consists of water and a mass fraction of 2-15% sodium chloride, 4.5-12% bactericide, and 10-35% ethanol.

[0026] In a specific embodiment, the gross specimen can be a complete human corpse, a human organ, or an animal corpse and organ.

[0027] The following is a further description of the embodiments of the present invention in conjunction with specific examples. The raw materials and chemical reagents used in the following examples are all commercially available conventional products.

[0028] 1. Specific embodiments of the gross specimen preservation device of the present invention Example 1 The gross specimen preservation device of this embodiment is as follows: Figure 1 As shown, it includes a liquid storage tank 1 for containing preservation liquid, a reflux device 2 and a sealing cover 4, the reflux device 2 includes a circulation pipe 23, the liquid storage tank 1 is 2-5 meters in length and width and 1-2 meters in height, and the volume occupied by the macro specimen and the preservation liquid is 1 / 3-2 / 3 of the liquid storage tank.

[0029] The circulation pipeline 23 has a liquid inlet and a liquid outlet. The circulation pipeline 23 is provided with an inlet valve 21 near the liquid inlet and an outlet valve 22 near the liquid outlet. The circulation pipeline 23 is provided with a booster pump 24 and a filter 25 between the inlet valve 21 and the outlet valve 22. The booster pump 24 is used to pressurize and pump the liquid at the bottom of the storage liquid. The filter element of the filter 25 is PP cotton, which is used to filter out impurities in the pumped storage liquid, such as solid particulate matter. Assuming that the storage liquid in the storage device is 5 m 3 The flow rate of the reflux device 2 is 0.2~2.5m 3 / h, so that the preservation solution in the preservation equipment can achieve a reflux cycle within 2~25h.

[0030] The liquid inlet is located on the side wall of the liquid storage tank 1 close to the bottom of the tank, and the liquid outlet is provided with a spray device 3, and the spray device 3 is located above the liquid surface of the preservation liquid. The spray device 3 includes an annular pipe 31 arranged along the inner wall of the liquid storage tank 1, and a nozzle for spraying (not shown in the figure) is provided on the annular pipe 31, and the angle between the direction of the nozzle and the liquid surface of the preservation liquid is 30°~60°. It can be understood that the liquid outlet can also be provided with a spray device, and the spray device includes an annular pipe 31 arranged along the inner wall of the liquid storage tank 1, and a nozzle for spraying is provided on the annular pipe 31. Compared with spraying, spraying is more conducive to the volatilization of the solvent and the formation of a concentration difference of the preservation liquid. Preferably, the liquid outlet is provided with a spray device.

[0031] The liquid storage tank 1 is provided with an ultraviolet sterilization device 5 on the side wall above the liquid level of the preservation liquid and below the spray device 3. The ultraviolet sterilization device 5 is installed at a position 10-20 cm below the annular pipe 31. The operation time of the spray device 3 is 4-24 hours / day. When the spray device 3 is in operation, the ultraviolet sterilization device 5 is turned on synchronously.

[0032] The opening of the liquid storage tank 1 is provided with a water sealing groove 11, which is composed of an annular inner wall 12 parallel to the side wall of the liquid storage tank 1, an annular outer wall 13 and a groove bottom wall. The annular inner wall 12 belongs to the edge of the liquid storage tank side wall near the opening to form an annular inner wall 12. The edge of the sealing cover 4 is provided with a cover edge folded downward for sealing with the water sealing groove 11. The sealing cover 4 is provided with a hanging ring to facilitate the movement of the sealing cover 4. The cover edge cooperates with the water sealing groove so that the cover edge is immersed in the aqueous solution to achieve water sealing of the storage device. When the storage liquid contains formaldehyde, the aqueous solution used for water sealing contains a formaldehyde remover for absorbing volatilized formaldehyde.

[0033] 2. Specific embodiments of the method for preserving gross specimens of the present invention Example 2 The method for preserving the gross specimen of this embodiment is as follows: The gross specimen is placed in the preservation solution of the preservation device of Example 1, and the preservation solution at the bottom is sucked to the top of the liquid surface for spraying and reflux. The preservation solution consists of water and 12% sodium chloride by mass, 1.5% bactericide tebuconazole, and 3.5% preservative formaldehyde. The spraying duration is 8 hours / day, and ultraviolet sterilization is performed above the liquid surface of the preservation solution during spraying. The preservation device adopts water sealing, and the aqueous solution used for water sealing is potassium permanganate aqueous solution, which is used to absorb volatile formaldehyde.

[0034] After the gross specimen was preserved for 6 months using the preservation method of this embodiment, the preservation solution at 2 cm from the liquid surface of the preservation solution and 2 cm from the bottom wall of the preservation device were taken for sodium chloride concentration testing. The test found that the sodium chloride concentration at 2 cm from the liquid surface of the preservation solution was 12.75%, and the sodium chloride concentration of the preservation solution at the bottom of the preservation device was 11.46%, which proved that the preservation method provided by the present invention can form a sodium chloride concentration difference, thereby improving the bactericidal effect of the gas-liquid contact interface, improving the growth of bacteria and other microorganisms during the long-term preservation of the gross body, and improving the antibacterial, antibacterial and bactericidal effects during the long-term preservation of the gross body.

[0035] Example 3 The method for preserving the gross specimen of this embodiment is as follows: The gross specimen is placed in the preservation solution of the preservation device of Example 1, and the preservation solution at the bottom is sucked to the top of the liquid surface for spray reflux. The preservation solution consists of water and 10% sodium chloride by mass, 12% fungicide flusilazole, and 10% preservative ethanol. The spraying duration is 8 hours / day, and ultraviolet sterilization is performed above the liquid surface of the preservation solution during spraying. The preservation device adopts water sealing, and the aqueous solution used for water sealing is pure water.

[0036] After the gross specimens were preserved for 8 months using the preservation method of this embodiment, the preservation solutions at 2 cm from the surface of the preservation solution and 2 cm from the bottom wall of the preservation device were taken for sodium chloride concentration tests. The test found that the sodium chloride concentration at 2 cm from the surface of the preservation solution was 10.85%, and the sodium chloride concentration of the preservation solution at the bottom of the preservation device was 9.38%.

[0037] Example 4 The method for preserving the gross specimen of this embodiment is as follows: The gross specimen is placed in the preservation solution of the preservation device of Example 1, and the preservation solution at the bottom is sucked to the top of the liquid surface for spray reflux. The preservation solution consists of water and 2% sodium chloride by mass, 4.5% bactericide penconazole, and 35% preservative ethanol. The spraying duration is 12 h / day, and ultraviolet sterilization is performed above the liquid surface of the preservation solution during spraying. The preservation device adopts water sealing, and the aqueous solution used for water sealing is pure water.

[0038] After the gross specimens were preserved for 6 months using the preservation method of this embodiment, the preservation solutions at 2 cm from the surface of the preservation solution and 2 cm from the bottom wall of the preservation device were respectively taken for sodium chloride concentration testing. The test found that the sodium chloride concentration at 2 cm from the surface of the preservation solution was 2.15%, and the sodium chloride concentration of the preservation solution at the bottom of the preservation device was 1.91%.

[0039] Example 5 The method for preserving the gross specimen of this embodiment is as follows: The gross specimen is placed in the preservation solution of the preservation device of Example 1, and the preservation solution at the bottom is sucked to the top of the liquid surface for spraying and reflux. The preservation solution consists of water and 5% sodium chloride by mass, 0.25% bactericide triadimefon, and 10% preservative formaldehyde. The spraying duration is 4 hours per day, and ultraviolet sterilization is performed above the liquid surface of the preservation solution during spraying. The preservation device adopts water sealing, and the aqueous solution used for water sealing is potassium permanganate aqueous solution, which is used to absorb volatile formaldehyde.

[0040] After the gross specimens were preserved for 6 months using the preservation method of this embodiment, the preservation solutions at 2 cm from the surface of the preservation solution and 2 cm from the bottom wall of the preservation device were taken for sodium chloride concentration tests. The test found that the sodium chloride concentration at 2 cm from the surface of the preservation solution was 5.32%, and the sodium chloride concentration of the preservation solution at the bottom of the preservation device was 4.81%.

[0041] 3. Comparative Proportion Comparative Example 1 The method for preserving the gross specimens of this comparative example is as follows: The gross specimens were immersed in preservation solution without spraying or reflux of the preservation solution at the bottom. The preservation solution consisted of water and 12% sodium chloride by mass, 1.5% bactericide tebuconazole, and 3.5% preservative formaldehyde by mass. Ultraviolet sterilization was performed above the surface of the preservation solution. The duration of ultraviolet sterilization was 8 hours per day, and potassium permanganate aqueous solution was used to absorb the volatile formaldehyde.

[0042] After 8 months of preservation using the preservation method of Comparative Example 1, some of the gross specimens floated on the preservation solution, and a small part was exposed to the air, resulting in partial skin tissue drying and fungal infection and white hair. After 2 years of continued preservation, the gross specimens floating on the preservation solution even had large areas of skin tissue ulceration, and the gross specimens immersed in the preservation solution also began to show fungal infection and hair.

[0043] After being preserved for 8 months using the preservation method of Example 2, some of the gross specimens also floated on the preservation solution, and a small part of them were exposed to the air, but there was no drying of the skin tissue and white hair caused by fungal infection, and the gross specimens were well preserved; and after being preserved for 2 years using the preservation method of Example 2, the gross specimens floating on the preservation solution still did not show the above-mentioned drying and infection, and were still well preserved, and there was no fungal infection in the gross specimens in the preservation solution.

[0044] Comparative Example 2 The method for preserving the gross specimens of this comparative example is as follows: The gross specimen is immersed in the preservation solution without spraying or spraying backflow of the preservation solution at the bottom. The preservation solution consists of water and 2% sodium chloride by mass, 4.5% fungicide penconazole, and 35% preservative ethanol. Ultraviolet sterilization is carried out above the surface of the preservation solution. The duration of ultraviolet sterilization is 12 hours / day, and the aqueous solution used for water sealing is pure water.

[0045] After 12 months of storage using the storage method of Comparative Example 2, some of the gross specimens floated on the preservation solution, and some were even exposed to the air, with some skin tissue drying up, fungal infection and white hair, and even some skin tissue ulceration. After another 2 years of storage, large areas of skin tissue ulceration occurred in the gross specimens floating on the preservation solution, and fungal infection and hair growth began to appear in the gross specimens immersed in the preservation solution.

[0046] After 12 months of preservation using the preservation method of Example 4, some of the gross specimens also floated on the preservation solution, and a small part of them were exposed to the air, but there was no phenomenon of skin tissue drying, fungal infection, white hair, and skin tissue ulceration, and the gross specimens were well preserved; and after 2 years of preservation using the preservation method of Example 2, the gross specimens floating on the preservation solution still did not show the above-mentioned drying and infection, and were still well preserved, and the gross specimens in the preservation solution did not show fungal infection.

[0047] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A method for preserving a gross specimen, characterized in that: The following steps are involved: The gross specimen is placed in a preservation solution of a preservation device, and the preservation solution at the bottom is intermittently or continuously pumped to the top of the preservation solution surface for spraying or mist reflux, wherein the preservation solution includes sodium chloride, bactericide, preservative and water.

2. The method for preserving a gross specimen according to claim 1, characterized in that: The mass fraction of the sodium chloride in the preservation solution is 2-15%.

3. The method for preserving a gross specimen according to claim 1, wherein: The sprayed or sprayed refluxed preservation solution is sterilized by ultraviolet light above the surface of the preservation solution.

4. The method for preserving a gross specimen according to claim 1, wherein: The duration of spraying or misting is 4~24h / day.

5. The method for preserving a gross specimen according to claim 1, wherein: The storage device is water-sealed, and when the preservative contains formaldehyde, the aqueous solution used for the water sealing contains a formaldehyde remover.

6. A device for preserving gross specimens, characterized in that: It comprises a liquid storage tank for containing preservation liquid and a reflux device, wherein the reflux device comprises a circulation pipe, wherein the circulation pipe has a liquid inlet and a liquid outlet, wherein the liquid inlet is located at the side wall of the liquid storage tank close to the bottom of the tank or the bottom wall of the tank, and the liquid outlet is provided with a spray device or a mist device, wherein the spray device or the mist device is located above the liquid level of the preservation liquid.

7. The gross specimen storage device according to claim 6, characterized in that: The spray device or the mist device comprises an annular pipe arranged along the inner wall of the liquid storage tank, and a nozzle for spraying or misting is arranged on the annular pipe.

8. The gross specimen storage device according to claim 7, characterized in that: The angle between the direction of the nozzle and the surface of the preservation solution is 30° to 60°.

9. The gross specimen storage device according to claim 6, characterized in that: The liquid storage tank is provided with an ultraviolet sterilizing device on a side wall which is higher than the liquid level of the preservation liquid and lower than the spraying device or the spraying device.

10. The gross specimen storage device according to claim 6, characterized in that: A water sealing groove is provided at the opening of the liquid storage tank, and the storage device has a sealing cover which is sealed with the water sealing groove.

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