Lipid prodrugs of pregnane neurosteroids and uses thereof

CN119306780APending Publication Date: 2025-01-14HARBOR THERAPY CORP +1
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Patent Information

Application Number
CN202411088317.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2019-01-07
Filing Date
2019-08-02
Publication Date
2025-01-14

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Abstract

The present invention provides lipid prodrugs of pregnane neurosteroids and uses thereof, and relates to lipid prodrugs directed to the lymphatic system, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of therapeutic agents comprising a portion of the lipid prodrugs. The present invention also provides methods of treating a disease, disorder or condition, such as those disclosed in the specification, comprising administering to a patient in need thereof the disclosed lipid prodrugs or pharmaceutical compositions thereof.
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Citation Information

Patent Citations

  • Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides

    US6013665A

  • Lymph directing prodrugs

    WO2016023082A1

  • Lymph directing prodrugs

    WO2017041139A1