Multi-modal fusion precise ablation system

Abstract

The invention provides a multi-mode fusion precise ablation system. The multi-mode fusion precise ablation system comprises a processing unit, a radio frequency treatment unit, a microwave treatment unit, an ultrasonic treatment unit, a monitoring unit, a navigation unit and a positioning unit. Wherein the processing unit is used for processing a data instruction and transmitting a signal, the radio frequency treatment unit comprises a driving device, the radio frequency treatment unit is used for performing radio frequency ablation treatment, the microwave treatment unit is used for microwave interventional treatment, and the ultrasonic treatment unit is used for ultrasonic ablation treatment. The monitoring unit comprises an image monitoring module and a body data monitoring module, and the navigation unit comprises a medical software module and a system integration module; multiple ablation modes are formed by combining the radio frequency treatment unit, the microwave treatment unit and the ultrasonic treatment unit, the high-precision positioning unit and the navigation unit are arranged, the appropriate ablation modes or combined modes can be selected according to tumor characteristics, the ablation area can be accurately controlled, and millimeter-level precision tumor ablation is achieved.

Description

Technical Field

[0001] The present invention relates to an ablation system, in particular to a multi-modality fusion precision ablation system, and belongs to the technical field of tumor treatment. Background Art

[0002] Tumors are new growths formed by the proliferation of local tissue cells. The acidity of tumors is slightly stronger than that of healthy body tissues. Tumors can form an "acid wall" to protect themselves from attacks by the immune system. Liver cancer and pancreatic cancer are both called "the king of cancers" and are extremely malignant tumors. Studies have found that tumor cells undergo metabolic changes that are different from normal cells and can metabolize through glycolysis and oxidative phosphorylation. Tumor ablation therapy is a local interventional treatment technology that directly destroys tumors using various physical methods. Treatment methods include radio frequency, microwave, freezing, high-frequency electrocautery, laser, high-energy focused ultrasound, or local injection of anhydrous ethanol, hot saline, hot distilled water, etc. Treatment routes include percutaneous, endoscopic or open surgery; In the existing tumor ablation treatment process, it is necessary to select the appropriate treatment method according to the characteristics of different tumors. A single treatment device cannot meet the treatment needs of different patients, and it is not convenient to perform a combination of multiple treatment methods. In order to solve the above technical problems, a multimodal fusion precise ablation system is proposed. Summary of the invention

[0003] In view of this, the present invention provides a multi-modal fusion precision ablation system to solve or alleviate the technical problems existing in the prior art and at least provide a beneficial option.

[0004] The technical solution of the present invention is implemented as follows: a multimodal fusion precision ablation system comprises a processing unit, a radiofrequency treatment unit, a microwave treatment unit, an ultrasound treatment unit, a monitoring unit, a navigation unit and a positioning unit; Among them, the processing unit is used to process data instructions and transmit signals, the radio frequency treatment unit includes a driving device, the radio frequency treatment unit is used to perform radio frequency ablation treatment, the microwave treatment unit is used for microwave interventional treatment, the ultrasound treatment unit is used for ultrasound ablation treatment, the monitoring unit includes an image monitoring module and a body data monitoring module, and the navigation unit includes a medical software module and a system integration module.

[0005] Further preferably, the radio frequency treatment unit includes a radio frequency treatment device, which uses low-frequency electromagnetic waves to act on diseased tissues in the human body, causing polar water molecules in the tissue to move at high speed, generating heat, and coagulating proteins at low temperatures, causing them to lose their activity, and finally causing them to fall off through the body's rejection, thereby achieving a treatment purpose. The radio frequency treatment device is installed on one side of the driving device.

[0006] Further preferably, the microwave therapy unit includes a microwave generator, a coaxial cable and a microwave antenna, the microwave generator generates microwaves through a magnetron, the microwave antenna is connected to the microwave generator through a low-loss coaxial cable, and the microwaves are transmitted from the magnetron of the microwave generator to the tissue, and the microwave generator is installed on one side of the driving device.

[0007] Further preferably, the ultrasonic treatment unit includes a focused ultrasonic transmitting disk and an ultrasonic monitoring device. The focused ultrasonic transmitting disk utilizes the property that ultrasonic waves can pass through human tissue and focus on a specific target area to concentrate energy to a sufficient intensity so that the focal area reaches an instantaneous high temperature and destroys the target area tissue. The ultrasonic monitoring device monitors the ultrasonic image in real time to determine the planned target tumor. The focused ultrasonic transmitting disk and the ultrasonic monitoring device are both installed on one side of the driving device.

[0008] Further preferably, the surgical navigation system composed of the medical software module and the system integration module establishes truly three-dimensional, clearly-bounded, arbitrarily rotatable and incised vector stereo graphics of brain nuclei and lesion sites based on MRI and CT tomographic plane images. The entire software part includes five modules: data and resource management, tomographic image processing, three-dimensional reconstruction, surgical simulation and plan formulation, and real-time three-dimensional navigation. The system hardware includes an image data input and output subsystem, an operating platform, and an optical positioning subsystem.

[0009] Further preferably, the positioning unit has a built-in algorithm module, which utilizes a time difference measurement algorithm and a received signal strength indication algorithm. The time difference measurement algorithm calculates the target position by measuring the time delay difference between signals reaching different receivers, while the received signal strength indication algorithm determines the target position by measuring the amplitude change of the signal.

[0010] Further preferably, the image monitoring module performs real-time monitoring of the designated area during the treatment process to ensure safety during the treatment process, and the body data monitoring module performs real-time monitoring of the patient's body data to facilitate real-time confirmation of the patient's body data status.

[0011] Further preferably, the driving device drives the radio frequency treatment unit, the microwave treatment unit and the ultrasound treatment unit to move, and different treatment methods are selected according to the treatment mode.

[0012] Further preferably, the positioning unit has an error of millimeter level to ensure the control accuracy of the ablation area, and the radio frequency treatment unit, microwave treatment unit and ultrasound treatment unit have built-in sensors to facilitate positioning in cooperation with the positioning unit.

[0013] The embodiment of the present invention has the following advantages due to the adoption of the above technical solution: 1. The present invention combines radio frequency treatment units, microwave treatment units and ultrasound treatment units to form multiple ablation modes, and is equipped with high-precision positioning units and navigation units. It can select appropriate ablation modes or combination modes according to tumor characteristics, accurately control the ablation area, and achieve tumor ablation with millimeter-level accuracy; 2. The present invention integrates a real-time monitoring function to monitor the treatment area in real time and monitor the patient's physical data in real time to ensure safety during the treatment process.

[0014] The above summary is for illustrative purposes only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present invention will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 This is a diagram of the multi-modality fusion precision ablation system of the present invention; Figure 2 This is a functional module diagram of the multimodal fusion precision ablation system in the present invention.

[0017] Figure numerals: 10. processing unit; 11. radio frequency treatment unit; 12. microwave treatment unit; 13. ultrasound treatment unit; 14. monitoring unit; 15. navigation unit; 16. positioning unit; 17. radio frequency treatment device; 18. driving device; 19. microwave generator; 21. coaxial cable; 22. microwave antenna; 23. focused ultrasound transmitting disk; 24. ultrasound monitoring device; 25. image monitoring module; 26. body data monitoring module; 27. medical software module; 28. system integration module; 29. ​​algorithm module. DETAILED DESCRIPTION

[0018] In the following, only some exemplary embodiments are briefly described. As those skilled in the art will appreciate, the described embodiments may be modified in various ways without departing from the spirit or scope of the present invention. Therefore, the drawings and descriptions are considered to be exemplary and non-restrictive in nature.

[0019] The embodiments of the present invention are described in detail below with reference to the accompanying drawings.

[0020] like Figure 1-2As shown, the embodiment of the present invention provides a multi-modal fusion precision ablation system, which is composed of a processing unit 10, a radio frequency treatment unit 11, a microwave treatment unit 12, an ultrasound treatment unit 13, a monitoring unit 14, a navigation unit 15 and a positioning unit 16; The processing unit 10 is used to process data instructions and transmit signals, the radio frequency treatment unit 11 is used to perform radio frequency ablation treatment, the microwave treatment unit 12 is used for microwave interventional treatment, the ultrasound treatment unit 13 is used for ultrasound ablation treatment, the monitoring unit 14 integrates a real-time monitoring function to ensure safety during the treatment process, and the navigation unit 15 cooperates with the positioning unit 16 to accurately control the ablation area to achieve tumor ablation with millimeter-level accuracy.

[0021] The radio frequency treatment unit 11 includes a radio frequency treatment device 17 and a driving device 18. The radio frequency treatment device 17 uses low-frequency electromagnetic waves to act on the diseased tissue of the human body, causing the polar water molecules in the tissue to move at high speed, generating heat, and coagulating the protein at low temperatures, causing it to lose its activity. Finally, the protein is caused to fall off through the body's rejection, thereby achieving the treatment purpose. The radio frequency treatment device 17 is installed on one side of the driving device 18, and the driving device 18 drives the radio frequency treatment device 17 to move to complete the switching of the ablation mode.

[0022] In one embodiment, the radiofrequency therapy device 17 is composed of five parts: an electric generator, a measurement and control unit, an electrode needle, a skin electrode and a computer. The system forms a closed loop, connecting the electrode needle to the patient's skin electrode. The measurement and control unit automatically adjusts the output power of radiofrequency ablation by monitoring the changes in parameters such as impedance and temperature of the tumor tissue, so that the tumor tissue quickly produces a large range of coagulative necrosis. The ablation electrode is the core component of the radiofrequency ablation instrument, which directly affects the size and shape of the coagulative necrosis. The shape of the coagulation zone should be spherical or oblate.

[0023] The microwave therapy unit 12 includes a microwave generator 19, a coaxial cable 21 and a microwave antenna 22. The microwave generator 19 generates microwaves through a magnetron. The microwave antenna 22 is connected to the microwave generator 19 through a low-loss coaxial cable 21, and transmits the microwaves from the magnetron of the microwave generator 19 to the tissue. The microwave generator 19 is installed on one side of the driving device 18, and the driving device 18 drives the microwave generator 19 to move to switch the ablation mode.

[0024] In one embodiment, the microwave antenna 22 uses a water-circulating internal cooling antenna, so that high-power, long-time, and high-energy-level ablation can be implemented, and the shape of the ablation zone is more spherical.

[0025] The ultrasound treatment unit 13 includes a focused ultrasound transmitting disk 23 and an ultrasound monitoring device 24. The focused ultrasound transmitting disk 23 utilizes the characteristics of ultrasound waves that can pass through human tissues and focus on specific target areas to concentrate energy to a sufficient intensity, so that the focal area reaches an instantaneous high temperature and destroys the target area tissue. The ultrasound monitoring device 24 monitors the ultrasound image in real time to determine the target tumor selected in the plan. The entire treatment process is controlled by the system and provides timely feedback on the treatment effect. The focused ultrasound transmitting disk 23 and the ultrasound monitoring device 24 are both installed on one side of the driving device 18. The driving device 18 drives the ultrasound monitoring device 24 and the focused ultrasound transmitting disk 23 to move to complete the switching of the ablation mode. The free movement of the focus and the ultrasound monitoring device 24 in space can realize three-dimensional combined scanning treatment. Physicians can choose fast, flexible and effective treatment plans according to different patients and different tumors.

[0026] The navigation unit 15 includes a medical software module 29 and a system integration module 28. The surgical navigation system composed of the medical software module 29 and the system integration module 28 establishes a truly three-dimensional, clearly-bounded, arbitrarily rotatable, cut and infinitely scalable vector stereoscopic image of brain nuclei and lesion sites based on MRI and CT tomographic plane images. The entire software part includes five modules: data and resource management, tomographic image processing, three-dimensional reconstruction, surgical simulation and plan formulation, and real-time three-dimensional navigation. The system hardware includes an image data input and output subsystem, an operating platform, and an optical positioning subsystem.

[0027] The positioning unit 16 has a built-in algorithm module 27, which uses a time difference measurement algorithm and a received signal strength indication algorithm. The time difference measurement algorithm calculates the target position by measuring the delay difference between the signals reaching different receivers, while the received signal strength indication algorithm determines the target position by measuring the amplitude change of the signal.

[0028] In one embodiment, the image monitoring module 25 performs real-time monitoring of the designated area during the treatment process to ensure safety during the treatment process, and the body data monitoring module 26 performs real-time monitoring of the patient's body data to facilitate real-time confirmation of the patient's body data status.

[0029] In one embodiment, the driving device 18 drives the radio frequency treatment unit 11, the microwave treatment unit 12 and the ultrasound treatment unit 13 to move, and different treatment methods or combined treatments are selected according to the treatment mode.

[0030] In one embodiment, the positioning unit 16 has an error of millimeter level to ensure the control accuracy of the ablation area. The radio frequency treatment unit 11 , the microwave treatment unit 12 and the ultrasound treatment unit 13 have built-in sensors to facilitate positioning with the positioning unit 16 .

[0031] When the present invention is working: according to the patient's tumor characteristics, a suitable ablation mode or combination mode is selected, and the radio frequency therapy device 17, the microwave generator 19, the focused ultrasound transmitting disk 23 and the ultrasound monitoring device 24 are driven by the driving device 18 to move, and different treatment modes or combination modes are switched. The ablation area is precisely controlled by the navigation unit 15 in cooperation with the positioning unit 16 to achieve tumor ablation with millimeter-level accuracy. At the same time, during the treatment, the ablation area and the patient's body data are monitored in real time by the monitoring unit 14, and the ultrasound monitoring device 24 is cooperated to ensure safety. During the operation, the navigation unit 15 cooperates with the positioning unit 16 to provide the doctor with surgical support with three-dimensional position information, which greatly reduces the surgical wound and minimizes the physical pain of the surgical patient.

[0032] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art can easily think of various changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. Multi-modal fusion precision ablation system, characterized by: It comprises a processing unit (10), a radio frequency treatment unit (11), a microwave treatment unit (12), an ultrasound treatment unit (13), a monitoring unit (14), a navigation unit (15) and a positioning unit (16); The processing unit (10) is used to process data instructions and transmit signals, the radio frequency treatment unit (11) includes a driving device (18), the radio frequency treatment unit (11) is used to perform radio frequency ablation treatment, the microwave treatment unit (12) is used for microwave interventional treatment, the ultrasound treatment unit (13) is used for ultrasound ablation treatment, the monitoring unit (14) includes an image monitoring module (25) and a body data monitoring module (26), and the navigation unit (15) includes a medical software module (29) and a system integration module (28).

2. The multimodal fusion precision ablation system according to claim 1, characterized in that: The radio frequency treatment unit (11) comprises a radio frequency treatment device (17). The radio frequency treatment device (17) uses low-frequency electromagnetic waves to act on diseased tissues of the human body, causing polar water molecules in the tissues to move at high speed, generating heat, causing proteins to coagulate at low temperatures, thereby losing their activity, and finally causing them to fall off through the body's rejection, thereby achieving a treatment purpose. The radio frequency treatment device (17) is mounted on one side of the driving device (18).

3. The multimodal fusion precision ablation system according to claim 1, characterized in that: The microwave treatment unit (12) comprises a microwave generator (19), a coaxial cable (21) and a microwave antenna (22); the microwave generator (19) generates microwaves through a magnetron; the microwave antenna (22) is connected to the microwave generator (19) through a low-loss coaxial cable (21) and transmits the microwaves from the magnetron of the microwave generator (19) to the tissue; and the microwave generator (19) is installed on one side of a driving device (18).

4. The multimodal fusion precision ablation system according to claim 1, characterized in that: The ultrasound treatment unit (13) comprises a focused ultrasound transmitting disk (23) and an ultrasound monitoring device (24). The focused ultrasound transmitting disk (23) utilizes the property that ultrasound waves can pass through human tissue and focus on a specific target area to concentrate energy to a sufficient intensity, so that the focal area reaches an instantaneous high temperature and destroys the target area tissue. The ultrasound monitoring device (24) monitors ultrasound images in real time to determine the target tumor selected in the plan. The focused ultrasound transmitting disk (23) and the ultrasound monitoring device (24) are both installed on one side of the driving device (18).

5. The multimodal fusion precision ablation system according to claim 1, characterized in that: The surgical navigation system composed of the medical software module (29) and the system integration module (28) establishes a truly three-dimensional, clearly-bounded, arbitrarily rotatable and infinitely scalable vector stereogram of brain nuclei and lesion sites based on MRI and CT tomographic plane images. The entire software part includes five modules: data and resource management, tomographic image processing, three-dimensional reconstruction, surgical simulation and program formulation, and real-time three-dimensional navigation. The system hardware includes an image data input and output subsystem, an operating platform, and an optical positioning subsystem.

6. The multimodal fusion precision ablation system according to claim 1, characterized in that: The positioning unit (16) has a built-in algorithm module (27), and the algorithm module (27) uses a time difference measurement algorithm and a received signal strength indication algorithm. The time difference measurement algorithm calculates the target position by measuring the time delay difference between signals reaching different receivers, while the received signal strength indication algorithm determines the target position by measuring the amplitude change of the signal.

7. The multimodal fusion precision ablation system according to claim 1, characterized in that: The image monitoring module (25) monitors the designated area in real time during the treatment process to ensure safety during the treatment process, and the body data monitoring module (26) monitors the patient's body data in real time to facilitate real-time confirmation of the patient's body data status.

8. The multimodal fusion precision ablation system according to claim 1, characterized in that: The driving device (18) drives the radio frequency treatment unit (11), the microwave treatment unit (12) and the ultrasound treatment unit (13) to move, and different treatment methods are selected according to the treatment mode.

9. The multimodal fusion precision ablation system according to claim 1, characterized in that: The positioning unit (16) has an error of millimeters, ensuring the control accuracy of the ablation area; the radio frequency treatment unit (11), the microwave treatment unit (12) and the ultrasound treatment unit (13) have built-in sensors, facilitating positioning in cooperation with the positioning unit (16).

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