Testing system and method of auditory brainstem reaction measuring instrument

Abstract

The invention discloses a testing system and method for an auditory brainstem reaction measuring instrument, relates to the technical field of testing of auditory brainstem reaction measuring instruments, and solves the problem that performance parameters of a physiological electric reaction measuring part of an auditory brainstem reaction measuring instrument cannot be tested in the prior art. The system comprises a signal generation module, an audio amplification module, an acoustic coupler, an attenuation circuit module, a main control module, a display module and a dual-channel signal acquisition module, and is used for converting an acoustic signal sent by an air conduction earphone of the auditory brainstem response measuring instrument into an electric signal for triggering the signal generation module to start; therefore, a sinusoidal signal can be automatically output according to the sound signal, the sinusoidal signal is attenuated and then input to an electrode input interface of the auditory brainstem response measuring instrument, and the amplitude measurement error and the incubation period measurement error of the auditory brainstem response measuring instrument can be obtained by analyzing the waveform and the amplitude collected by the dual-channel signal collection module.

Description

Technical Field

[0001] The present application relates to the technical field of auditory brainstem response measuring instrument testing, and in particular to a testing system and method of an auditory brainstem response measuring instrument. Background Art

[0002] Evoked potential (EP): The bioelectric changes related to external stimulation (such as auditory or visual sensory stimulation) produced by the nervous system. This electrical activity extracted and recorded from the electroencephalogram is called evoked potential.

[0003] Auditory evoked potentials (AEP): Evoked potentials induced by sound waves or vibration stimulation of the auditory system and recorded by electrodes.

[0004] Auditory brainstem response (ABR): A transient auditory evoked potential generated in the inner ear, auditory nerve and brainstem caused by short-term sound or vibration stimulation.

[0005] Objective audiometry is a general term for a type of audiometry that does not require the subject's subjective cooperation. It uses the subject's physiological response to sound stimulation to determine the subject's hearing. The results are not affected by subjective factors such as the subject's age, intelligence, and mental state at the time of the test. The test results are objective and highly accurate.

[0006] The auditory brainstem response meter is one of the important objective audiometric devices, which is widely used in audiological research, hearing disease detection and diagnosis, newborn hearing screening, forensic identification and other fields.

[0007] Examination method: In a quiet or sleeping environment, degrease and clean the forehead, between the eyebrows, and behind the ears of the subject, then stick electrodes on them, connect wires, insert earphones into the ear canals, and stimulate clicking sounds through the earphones. The positive waves that appear in the first 10 seconds are recorded sequentially on the scalp on top of the head, and the latency, peak value, and interval of these waves are observed.

[0008] The principle of the auditory brainstem response meter is to give a specific sound (vibration) stimulation signal to the human ear, and the electroencephalogram detection system records and analyzes the bioelectric response of the auditory nerve and brainstem pathway to achieve an objective hearing test. The auditory brainstem response meter can be divided into two parts in principle: the sound stimulation system and the physiological electrical response measurement system: the sound stimulation part and the physiological electrical response measurement part.

[0009] The industry currently has relatively clear index requirements and testing methods for the acoustic parameters of the sound stimulation part, but there is no clear testing method and testing system for the physiological electrical (EEG) response measurement part of the auditory brainstem response meter. Among them, latency and amplitude measurement accuracy are important parameters of the physiological electrical response measurement part. Summary of the invention

[0010] The purpose of the present application is to overcome the problem in the prior art that the performance parameters of the physiological electrical response measurement part of the auditory brainstem response measuring instrument cannot be tested, and to provide a testing system and method for the auditory brainstem response measuring instrument.

[0011] In a first aspect, a test system for an auditory brainstem response measuring instrument is provided, comprising a signal generating module for outputting a sinusoidal wave signal with adjustable frequency and amplitude, wherein a trigger end of the signal generating module is electrically connected to an audio amplification module, an input end of the audio amplification module is electrically connected to an acoustic coupler, an output end of the signal generating module is electrically connected to an attenuation circuit module, a control end of the attenuation circuit module is electrically connected to a main control module, the main control module is electrically connected to a display module, and the main control module is electrically connected to a dual-channel signal acquisition module, wherein a first channel of the dual-channel signal acquisition module is used to connect to an air conduction headphone input end of a device under test, and a second channel of the dual-channel signal acquisition module is used to connect to an output end of the attenuation circuit module.

[0012] In some possible implementations, the signal generating module is triggered and started by the output electrical signal of the audio amplifying module, and the triggering delay time and the duration of the output after triggering of the signal generating module are both adjustable.

[0013] In some possible implementations, the attenuation multiple of the attenuation circuit module is adjusted by the main control module, and the attenuation circuit module is used to attenuate the sinusoidal wave signal output by the signal generation module into a small signal without changing the signal-to-noise ratio.

[0014] In some possible implementations, the display module is used to display the waveform and amplitude of the signal collected by the dual-channel signal collection module, as well as the test results.

[0015] In some possible implementations, the air conduction earphone of the device under test is coupled to an acoustic coupler, and the acoustic coupler is used to convert an acoustic signal into an electrical signal.

[0016] In a second aspect, a method for testing the amplitude measurement accuracy of an auditory brainstem response measuring instrument is provided, comprising a test system as in any one of the implementations of the first aspect above, wherein the method for testing the amplitude measurement accuracy comprises:

[0017] S101, coupling the acoustic coupler to the air conduction earphone of the device under test, and electrically connecting the output end of the attenuation circuit module to the electrode input interface of the device under test;

[0018] S102, setting the attenuation multiple of the attenuation circuit module to 1 through the main control module;

[0019] S103, setting the sine wave frequency, amplitude, trigger delay time and duration of the signal generation module output and recording the initial peak-to-peak voltage value L collected in the second channel when the attenuation circuit module is not attenuated S-0 ;

[0020] S104, increasing the attenuation multiple of the attenuation circuit module, and calculating the amplitude measurement error according to the peak-to-peak voltage value displayed by the device under test and the current attenuation multiple;

[0021] S105, repeatedly executing step S104 until the calculated amplitude measurement error exceeds a preset allowable value or the number of repetitions reaches a preset threshold.

[0022] In some possible implementations, the amplitude measurement error is calculated as:

[0023] ΔL X =L M-X -L S-0 / X

[0024] Where, ΔL X is the amplitude measurement error of the device under test, L M-X is the peak-to-peak voltage value displayed by the device under test, L S-0 is the initial peak-to-peak voltage value collected in the second channel when the attenuation circuit is not attenuated, and X is the current attenuation multiple.

[0025] In a second aspect, a method for testing the accuracy of latency measurement of an auditory brainstem response measuring instrument is provided, comprising a test system as in any one of the implementations of the first aspect above, the method for testing the accuracy of latency measurement comprising:

[0026] S201, coupling the acoustic coupler to the air conduction earphone of the device under test, and electrically connecting the output end of the attenuation circuit module to the electrode input interface of the device under test;

[0027] S202, setting the attenuation multiple of the attenuation circuit module through the main control module;

[0028] S203, setting the sine wave frequency, amplitude, trigger delay time and duration of the signal generation module output;

[0029] S204 , calculating the latency measurement error according to the latency displayed by the device under test and the moment when the amplitude of the first waveform of the first channel and the second channel displayed by the display module rises to 10% of the peak-to-peak value.

[0030] In some possible implementations, the trigger delay time of the signal generating module is set to any value between 3 ms and 5 ms.

[0031] In some possible implementations, the calculation formula for the latency measurement error is:

[0032] Δt=t M -(t2-t1)

[0033] Where Δt is the latency measurement error, t M is the latency of the device under test locking the display, t1 is the moment when the amplitude of the first waveform of the first channel displayed by the display module rises to 10% of the peak-to-peak value, and t2 is the moment when the amplitude of the first waveform of the second channel displayed by the display module rises to 10% of the peak-to-peak value.

[0034] The present application has the following beneficial effects: the acoustic signal emitted by the air conduction earphone of the auditory brainstem response measuring instrument can be converted into an electrical signal for starting a trigger signal generating module, so that a sinusoidal signal can be automatically output according to the acoustic signal, and after attenuation, the signal is input to the electrode input interface of the auditory brainstem response measuring instrument. By analyzing the waveform and amplitude collected by the dual-channel signal acquisition module, the amplitude measurement error and latency measurement error of the auditory brainstem response measuring instrument can be obtained, thus filling the gap that the performance parameters of the physiological electrical response measurement part of the auditory brainstem response measuring instrument cannot be tested. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] The drawings constituting a part of the present application are used to provide a further understanding of the present application. The illustrative embodiments of the present application and their descriptions are used to explain the present application and do not constitute an improper limitation on the present application.

[0036] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0037] Figure 1 is a structural block diagram of a test system of an auditory brainstem response measuring instrument according to Example 1 of the present application;

[0038] Figure 2 is a flow chart of a method for testing the amplitude measurement accuracy of an auditory brainstem response measuring instrument according to Example 2 of the present application;

[0039] Figure 3 is a flow chart of a method for testing the accuracy of latency measurement of an auditory brainstem response measuring instrument according to Example 3 of the present application;

[0040] Figure 4 It is a schematic diagram of latency measurement in the latency measurement accuracy test method of the auditory brainstem response measuring instrument in Example 3 of the present application.

[0041] Reference numerals:

[0042] 100, signal generation module; 200, audio amplification module; 201, acoustic coupler; 300, attenuation circuit module; 400, main control module; 500, display module; 600, dual-channel signal acquisition module; 700, device under test; 701, air conduction earphone; 702, electrode input interface. DETAILED DESCRIPTION

[0043] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0044] Example 1

[0045] like Figure 1 As shown, a test system of an auditory brainstem response measuring instrument involved in Example 1 of the present application includes a signal generating module 100, which can output a sine wave signal with adjustable frequency and amplitude, and has a trigger start function, an adjustable trigger delay time, and an adjustable duration of output after each trigger; an audio amplifier module 200 is used to amplify the input weak electrical signal so that the amplified signal is higher than the trigger level of the signal generating module 100 (so that the signal output by the audio amplifier module 200 can trigger the output of the signal generating module 100); the attenuation multiple of the attenuation circuit module 300 can be adjusted by the main control module 400, and is used to attenuate the signal output by the signal generating module 100 into a sufficiently weak small signal without changing the signal-to-noise ratio of the original signal. The dual-channel signal acquisition module 600 is used to synchronously acquire the waveform and amplitude of the electrical signals of the two channels, and transmit the data to the main control module 400, and display it in the form of a waveform on the display module 500, such as: a display screen.

[0046] When in use, the air conduction earphone 701 of the auditory brainstem response measuring instrument (i.e., the device under test 700) needs to be coupled with the acoustic coupler 201, and the acoustic coupler 201 converts the sound signal into an electrical signal. The output of the acoustic coupler 201 is connected to the input end of the audio amplifier module 200; the audio amplifier module 200 amplifies the electrical signal and inputs it to the trigger end of the signal generation module 100; the electrical input end on the air conduction earphone 701 is connected to the first channel of the dual-channel signal acquisition module 600. The output of the signal generation module 100 is connected to the electrode input interface 702 of the auditory brainstem response measuring instrument and the second channel of the dual-channel signal acquisition module 600 after passing through the attenuation circuit module 300; the collected data of the dual-channel signal acquisition module 600 is sent to the main control module 400, and the waveform and amplitude are displayed on the display module 500 after processing; the main control module 400 can control the attenuation multiple of the attenuation circuit module 300 through the IO port.

[0047] Example 2

[0048] like Figure 2 As shown, the amplitude measurement accuracy test method of an auditory brainstem response measuring instrument involved in Example 2 of the present application, the test principle is: after the auditory brainstem response measuring instrument sends out a stimulus sound, the test system sends out an EEG simulation signal and inputs it into the electrode input of the auditory brainstem response measuring instrument, and checks the measurement indication of the auditory brainstem response measuring instrument for this simulation signal, and the measurement error can be obtained by analysis and comparison. By continuously reducing the amplitude of the EEG simulation signal, the measurement error at different amplitudes can be obtained.

[0049] The specific test method is as follows:

[0050] S101, coupling the acoustic coupler 201 to the air conduction earphone 701 of the device under test 700, and electrically connecting the output end of the attenuation circuit module 300 to the electrode input interface 702 of the device under test 700;

[0051] S102, setting the attenuation multiple of the attenuation circuit module 300 to 1 (i.e., initial state, no attenuation) through the main control module 400;

[0052] S103, setting the sine wave frequency, amplitude, trigger delay time and duration of the signal generating module 100 output, the purpose is to make the signal generating module 100 output a sine wave frequency of a specified frequency and amplitude, for example: a sine signal with a frequency of 1kHz and an amplitude of 100μV, a trigger delay time of any value in the range of 3 to 5ms, and a duration of any value in the range of 3 to 5ms, so that the signal generating module 100 generates an electrical signal equal to or slightly greater than 100μV on the second channel of the dual-channel signal acquisition module 600. When the trigger end of the signal generating module 100 receives the trigger signal, the signal generating module 100 outputs a sine wave signal of a specified duration after the set trigger delay time, and records the initial peak-to-peak voltage value L collected on the second channel when the attenuation circuit module 300 is not attenuated. S-0 ;

[0053] S104, keeping other measurement conditions unchanged, only increasing the attenuation multiple of the attenuation circuit module 300, and calculating the amplitude measurement error according to the peak-to-peak voltage value displayed by the device under test 700 and the current attenuation multiple;

[0054] Specifically, the calculation formula for the amplitude measurement error is:

[0055] ΔL X =L M-X -L S-0 / X

[0056] In, ΔL X is the amplitude measurement error of the device under test 700, L M-X is the peak-to-peak voltage value displayed by the device under test 700, L S-0 is the peak-to-peak voltage value collected in the second channel when the attenuation multiple of the attenuation circuit module 300 is set to 1, and X is the current attenuation multiple.

[0057] S105, repeat step S104 until the calculated amplitude measurement error exceeds the preset allowable value or the number of repetitions reaches the preset threshold, for example: increase the attenuation multiple to 5, according to the calculation formula of the amplitude measurement error: ΔL X =L M-X -L S-0 / X, calculate the amplitude measurement error at this time, then increase the attenuation multiple to 10, according to the calculation formula of the amplitude measurement error: ΔL X =L M-X -L S-0 / X, calculate the amplitude measurement error at this time, continue to reduce the amplitude and calculate and record the amplitude measurement error. By continuously reducing the amplitude of the EEG simulation signal (that is, continuously increasing the attenuation multiple while the output of the signal generator remains unchanged), the amplitude measurement error at different amplitudes can be obtained.

[0058] It should be noted that other specific implementations of the amplitude measurement accuracy test method of the auditory brainstem response measuring instrument in this embodiment can refer to the specific implementation of the test system of the auditory brainstem response measuring instrument mentioned above. To avoid redundancy, they will not be repeated here.

[0059] Example 3

[0060] like Figure 2 As shown, a method for testing the accuracy of latency measurement of an auditory brainstem response measuring instrument involved in Example 2 of the present application, the testing principle is: the time difference between the moment when the auditory brainstem response measuring instrument sends a stimulation signal and the moment when it recognizes the corresponding EEG signal is the latency measurement value of the auditory brainstem response measuring instrument. The error value can be obtained by comparing the latency measurement value of the auditory brainstem response measuring instrument with the actual time difference. The dual-channel signal acquisition module 600 synchronously acquires the time difference between the occurrence of the signals of the first channel and the second channel, which is the actual time difference. In this embodiment, the actual time difference can be adjusted by adjusting the trigger delay time of the signal generating module 100.

[0061] The specific test method is as follows:

[0062] S201, coupling the acoustic coupler 201 to the air conduction earphone 701 of the device under test 700, and electrically connecting the output end of the attenuation circuit module 300 to the electrode input interface 702 of the device under test 700;

[0063] S202, setting the attenuation multiple of the attenuation circuit module 300 through the main control module 400;

[0064] S203, setting the sine wave frequency, amplitude, trigger delay time and duration of the signal generating module 100 output, the purpose is to make the signal generating module 100 output a sine wave frequency of a specified frequency and amplitude, for example: a sine signal with a frequency of 1kHz and an amplitude of 100μV. Set the trigger delay time of the signal generating module 100 to any value in the range of 3 to 5ms, for example: the trigger delay time is set to 3ms, 4ms or 5ms, etc., and the duration is any value in the range of 3 to 5ms. When the trigger end of the signal generating module 100 receives the trigger signal, the signal generating module 100 outputs a sine wave signal of a specified duration after the set trigger delay time;

[0065] S204, calculating the latency measurement error according to the latency displayed by the device under test 700 and the moment when the amplitude of the first waveform of the first channel and the second channel displayed by the display module 500 rises to 10% of the peak-to-peak value. The calculation formula of the latency measurement error is:

[0066] Δt=t M -(t2-t1)

[0067] Where Δt is the latency measurement error, t M is the latency of the device under test 700 to lock the display, t1 is the moment when the amplitude of the first waveform of the first channel displayed by the display module 500 rises to 10% of the peak-to-peak value, and t2 is the moment when the amplitude of the first waveform of the second channel displayed by the display module 500 rises to 10% of the peak-to-peak value.

[0068] For example:

[0069] 1. Set the attenuation gear of the attenuation circuit module 300 to the initial state (attenuation multiple is 1, that is, no attenuation), set the output waveform of the signal generator to a sine wave, the frequency to 1kHz, the trigger delay time to 3ms, and the duration to 3ms.

[0070] 2. Adjust the output amplitude of the signal generator to a moderate value A within the range of the auditory brainstem response meter. For example, if the range of the auditory brainstem response meter is 0.5-5μV, the value of A can be 2-3μV.

[0071] 3. Start the measurement of the auditory brainstem response measuring instrument. The first channel of the dual-channel signal acquisition module can first collect a stimulation sound signal, and this signal will also trigger the signal generation module 100 to output a short (duration of 3ms) 1kHz sine wave. Then the second channel of the dual-channel signal acquisition module 600 can collect this sine signal. Press Figure 4 The time difference between these two moments is calculated by using the requirements of t2 and t1 and the calculation formula of the latency measurement error mentioned above: t2-t1. This time difference is compared with the latency t displayed by the auditory brainstem response measuring instrument. M By comparison, the latency error value can be obtained.

[0072] It should be noted that other specific implementation methods of the amplitude latency measurement accuracy test method of the auditory brainstem response measuring instrument in this embodiment can refer to the specific implementation methods of the test system of the auditory brainstem response measuring instrument mentioned above. To avoid redundancy, they will not be repeated here.

[0073] The above are only preferred specific implementations of the present application; however, the protection scope of the present application is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solution and its improved ideas of the present application within the technical scope disclosed in the present application, which should be included in the protection scope of the present application.

Claims

1. A test system for an auditory brainstem response measuring instrument, characterized in that: It comprises a signal generating module for outputting a sinusoidal wave signal with adjustable frequency and amplitude, wherein a trigger end of the signal generating module is electrically connected to an audio amplifier module, an input end of the audio amplifier module is electrically connected to an acoustic coupler, an output end of the signal generating module is electrically connected to an attenuation circuit module, a control end of the attenuation circuit module is electrically connected to a main control module, the main control module is electrically connected to a display module, and the main control module is electrically connected to a dual-channel signal acquisition module, wherein a first channel of the dual-channel signal acquisition module is used to connect to an air conduction headphone input end of a device under test, and a second channel of the dual-channel signal acquisition module is used to connect to an output end of the attenuation circuit module.

2. The test system of the auditory brainstem response measuring instrument according to claim 1, characterized in that: The signal generating module is triggered and started by the output electrical signal of the audio amplifying module, and the triggering delay time and the duration of the output after triggering of the signal generating module are both adjustable.

3. The test system of the auditory brainstem response measuring instrument according to claim 1, characterized in that: The attenuation multiple of the attenuation circuit module is adjusted by the main control module, and the attenuation circuit module is used to attenuate the sinusoidal wave signal output by the signal generation module into a small signal without changing the signal-to-noise ratio.

4. The test system of the auditory brainstem response measuring instrument according to any one of claims 1 to 3, characterized in that: The display module is used to display the waveform and amplitude of the signal collected by the dual-channel signal collection module, as well as the test results.

5. The test system of the auditory brainstem response measuring instrument according to claim 4, characterized in that: The air conduction earphone of the device under test is coupled to an acoustic coupler, and the acoustic coupler is used to convert an acoustic signal into an electrical signal.

6. A method for testing the amplitude measurement accuracy of an auditory brainstem response measuring instrument, characterized in that: Comprising the test system according to any one of claims 1 to 5, the amplitude measurement accuracy test method comprises: S101, coupling the acoustic coupler to the air conduction earphone of the device under test, and electrically connecting the output end of the attenuation circuit module to the electrode input interface of the device under test; S102, setting the attenuation multiple of the attenuation circuit module to 1 through the main control module; S103, setting the sine wave frequency, amplitude, trigger delay time and duration of the signal generation module output, and recording the initial peak-to-peak voltage value collected in the second channel when the attenuation circuit module is not attenuated; S104, increasing the attenuation multiple of the attenuation circuit module, and calculating the amplitude measurement error according to the peak-to-peak voltage value displayed by the device under test and the current attenuation multiple; S105, repeatedly executing step S104 until the calculated amplitude measurement error exceeds a preset allowable value or the number of repetitions reaches a preset threshold.

7. The amplitude measurement accuracy test method of the auditory brainstem response measuring instrument according to claim 6, characterized in that: The calculation formula for amplitude measurement error is: ΔL X =L M-X -L S-0 / X Where, ΔL X is the amplitude measurement error of the device under test, L M-X is the peak-to-peak voltage value displayed by the device under test, L S-0 is the initial peak-to-peak voltage value collected in the second channel when the attenuation circuit module is not attenuated, and X is the current attenuation multiple.

8. A method for testing the accuracy of latency measurement of an auditory brainstem response measuring instrument, characterized in that: Comprising the test system as described in any one of claims 1 to 5, the latency measurement accuracy test method comprises: S201, coupling the acoustic coupler to the air conduction earphone of the device under test, and electrically connecting the output end of the attenuation circuit module to the electrode input interface of the device under test; S202, setting the attenuation multiple of the attenuation circuit module through the main control module; S203, setting the sine wave frequency, amplitude, trigger delay time and duration of the signal generation module output; S204 , calculating the latency measurement error according to the latency displayed by the device under test and the moment when the amplitude of the first waveform of the first channel and the second channel displayed by the display module rises to 10% of the peak-to-peak value.

9. The method for testing the amplitude latency measurement accuracy of the auditory brainstem response measuring instrument according to claim 8, characterized in that: Set the trigger delay time of the signal generation module to any value between 3ms and 5ms.

10. The method for testing the amplitude latency measurement accuracy of the auditory brainstem response measuring instrument according to claim 8, characterized in that: The calculation formula for the latency measurement error is: Δt=t M -(t2-t1) Where Δt is the latency measurement error, t M is the latency of the device under test locking the display, t1 is the moment when the amplitude of the first waveform of the first channel displayed by the display module rises to 10% of the peak-to-peak value, and t2 is the moment when the amplitude of the first waveform of the second channel displayed by the display module rises to 10% of the peak-to-peak value.

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