Composite antiperspirant active polymer, preparation method and personal care product

Abstract

The invention provides a composite antiperspirant active polymer. An active substance of the composite antiperspirant active polymer is a combination of a green tea extract, a mulberry leaf extract and an aluminum-based antiperspirant active substance. According to the composite antiperspirant active polymer disclosed by the invention, the extract of natural plants and the aluminum-containing antiperspirant active matter are used as composite effective components, and the mulberry leaf extract and the green tea extract are matched with the aluminum-containing antiperspirant active matter, so that the obtained composite antiperspirant active polymer is non-irritant to skin, and has the advantages of no toxicity, no side effects and the like. And the release of ligand ions is influenced according to the pH value of sweat, so that the administration part achieves a remarkable and long-acting antiperspirant effect, and a satisfactory antiperspirant effect is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of personal daily products, and in particular to a composite antiperspirant active polymer, a preparation method and a personal care product. Background Art

[0002] Due to the hot weather in summer, people sweat easily. Sweat is usually colorless and odorless when secreted by sweat glands, but environmental stimulation and abnormal body metabolism can cause excessive microbial growth, thus forming skin diseases. Apocrine sweat glands only exist in the armpits, areola, umbilicus, anus, vulva and external auditory canal. Except for the armpits, the function of the glands in other parts is extremely weak and very little sweat is produced. The sweat secreted by the apocrine sweat glands is initially sterile. Under the action of microorganisms, the organic matter in the sweat is decomposed to form short-chain fatty acids and ammonia with a special odor, leading to the occurrence of apocrine bromhidrosis. Apocrine bromhidrosis occurring in the armpits, commonly known as body odor, seriously affects the patient's quality of life and work.

[0003] The mode of action of commercial antiperspirant compositions is based on aluminum salts, such as aluminum chlorohydrate, as the active ingredient of the antiperspirant. The aluminum salts here have astringent and denaturing effects. The astringent effect causes the sweat ducts to narrow. Due to the denaturing effect, sweat proteins precipitate and form protein blockages at the outer ends of the sweat ducts of the sweat glands, thereby reducing sweating overall and achieving an antiperspirant effect.

[0004] The topical medication treatment currently used is still defective, and cleaning and antiperspirants cannot remove microorganisms in a long-term manner. In a high-temperature outdoor environment, people with well-developed sweat glands will sweat after generally stopping the medication for 3-4 hours, which cannot guarantee the efficacy and can only reduce the immediate sweating effect. The surgical method has the disadvantages of large wounds, obvious scars and long recovery time, and most of them may relapse after surgery. Therefore, a simple nursing composition is needed to remove microorganisms in a long-term manner and inhibit the production of sweat gland secretions in a long-term manner. Summary of the invention

[0005] Purpose of the invention: The purpose of the present invention is to provide a composite antiperspirant active polymer, a preparation method and a personal care product, which has a good effect of reducing the secretion and excretion of sweat, has anti-fouling, antiperspirant, bactericidal and deodorizing functions, and has the characteristics of high efficiency, sustained release and long-term effect, fast effect, obvious deodorizing effect, not easy to relapse, and has broad application prospects.

[0006] The technical solution of the present invention:

[0007] In one aspect, the present invention provides a composite antiperspirant active polymer, wherein the active substance of the composite antiperspirant active polymer is a combination of green tea extract, mulberry leaf extract and an aluminum-based antiperspirant active substance.

[0008] In some embodiments, the green tea extract includes one or more combinations of green tea polyphenols, green tea caffeine, green tea aromatic oil, and green tea amino acids; preferably, the green tea extract refers to tea polyphenols, which have strong antioxidant and antibacterial properties and can be used as an active ingredient in antiperspirants.

[0009] In some embodiments, the mulberry leaf extract includes one or more combinations of mulberry leaf quercetin, mulberry leaf chlorogenic acid, mulberry leaf alkaloids (1-deoxynojirimycin), and mulberry leaf amino acids (γ-aminobutyric acid); preferably, the mulberry leaf extract refers to mulberry leaf quercetin.

[0010] In some embodiments, the preparation method of the extract comprises: pretreating the raw material, using ethanol aqueous solution as an extraction solvent, mixing it with the raw material, and placing it in an extraction device for stirring and extraction. The extraction temperature is usually controlled at 40-50°C, and the extraction time is 1-2 hours. After the extraction is completed, the solid residue is filtered out, extracted with ethyl acetate, and then rotary evaporated to obtain an extract, which is then purified by column chromatography and dried to obtain an extract. When the raw material is mulberry leaf, a mulberry leaf extract is obtained; when the raw material is green tea, a green tea extract is obtained.

[0011] In some embodiments, the aluminum-based antiperspirant active is of the general formula Al2(OH) x Q y . Hydroxyl halides defined by wH2O, wherein Q represents chlorine, bromine or iodine, x is a variable from 2 to 5, and x+y=6, and wH2O represents a hydrate variable, such as aluminum chlorohydrate.

[0012] In some embodiments, the method for preparing the composite antiperspirant active polymer comprises:

[0013] Step 1. Add a solution containing an aluminum-based antiperspirant active ingredient to an N,N-dimethylformamide (DMF) solution containing a mulberry leaf extract and a green tea extract, and mix well; add ethyl acetate dropwise under stirring, continue stirring at room temperature, wash the formed precipitate with ethanol three times, and ultrasonically disperse it in ethanol to obtain a colloidal solution.

[0014] Step 2. The colloidal solution prepared above is diluted with ethanol, and then an ethanol solution of 1,4-bis(imidazole-1-methyl)benzene and an ethanol solution containing an aluminum-based antiperspirant active substance are alternately added under vigorous stirring at room temperature to obtain a product. The product is recovered by centrifugation, washed with ethanol, and then dried overnight under vacuum conditions to obtain a composite antiperspirant active polymer.

[0015] In some embodiments, the solvent of the solution containing the aluminum-based antiperspirant active is methanol or ethanol, and the concentration of the solution is 0.1-0.5 mol / L.

[0016] In some embodiments, in step 1, the weight ratio of the mulberry leaf extract, the green tea extract and the aluminum-based antiperspirant active is 2-5:1-2:1-3; preferably, the weight ratio of the mulberry leaf extract, the green tea extract and the aluminum-based antiperspirant active is 3-4:1:2-3.

[0017] In some embodiments, in step 2, the volume ratio of the added molar amount of the 1,4-bis(imidazole-1-methyl)benzene and the aluminum-based antiperspirant active substance to the colloidal solution is 0.001-0.01 mol:10 ml.

[0018] In some embodiments, there is no fixed number of alternations. For example, the ethanol solution of 1,4-bis(imidazole-1-methyl)benzene can be added 5 times, and the ethanol solution of the aluminum-based antiperspirant active can be added 5 times, as long as the total amount of the added 1,4-bis(imidazole-1-methyl)benzene and the aluminum-based antiperspirant active meets the above requirements.

[0019] In some embodiments, the concentrations of the ethanol solution of 1,4-bis(imidazole-1-methyl)benzene and the ethanol solution of Zn(NO3)2·6H2O are both 0.01-0.05 mol / L.

[0020] Human sweat is acidic, and the formation and breaking of the coordination bond between the metal and the ligand of the composite antiperspirant active polymer is very sensitive to the change of the pH value of the surrounding environment. The amount of sweat will affect the pH value of the body surface. The coordination bond will be stimulated by the low pH of the surrounding environment and break, first releasing the aluminum-based antiperspirant active substance on the outside, and then releasing the aluminum-based antiperspirant active substance inside after disintegration. When there is no sweat on the body surface, the coordination bond will not break and the aluminum-based antiperspirant active substance will not be released, so as to achieve the purpose of long-term antiperspirant.

[0021] In another aspect, the present invention provides a personal care product that can achieve long-lasting antiperspirant, antiperspirant, bactericidal and deodorant effects. The raw materials of the personal care product include a carrier and a composite antiperspirant active polymer.

[0022] In some embodiments, the carrier can be understood as a solvent, or a chemical substance that can play the role of a solvent. For example, the carrier can be one of isododecane and alkyl benzoate. Alkyl benzoate refers to a low molecular weight ester mixture of benzoic acid and C12-15 alcohol.

[0023] The personal care product can take many suitable forms. For example, according to various aspects, the personal care product is a stick treatment, a body spray, a clear gel, or an aerosol treatment. The personal care product can contain various additional components. For example:

[0024] In some embodiments, the raw materials of the personal care product may further include a moisturizer, and the added weight of the moisturizer may be 0.001 wt%-5 wt% of the total weight of the personal care product.

[0025] In some embodiments, the raw materials of the personal care product may further include an odor trapping agent, and the added weight of the odor trapping agent may be 0.001 wt%-4 wt% of the total weight of the personal care product.

[0026] In some embodiments, the raw materials of the personal care product may also include one or more combinations of solubilizers, buffers, humectants, preservatives, etc. However, it should be noted that the buffer can only be alkaline or neutral to maintain the desired pH of the composition. When the pH is too low and acidic, the bond energy of the composite antiperspirant active polymer will be disconnected, aluminum ions will be released prematurely, and the ability to bind sweat will be lost prematurely.

[0027] Beneficial effects:

[0028] The composite antiperspirant active polymer described in the present invention uses natural plant extracts and aluminum-based antiperspirant active substances as composite effective ingredients, and mulberry leaf extract and green tea extract are combined with the aluminum-based antiperspirant active substances. The obtained composite antiperspirant active polymer has no irritation to the skin, and releases ligand ions according to the pH value of sweat, and achieves a significant and long-lasting antiperspirant effect at the administration site, achieving a satisfactory antiperspirant effect. Purpose of the invention: The purpose of the present invention is to provide a composite antiperspirant active polymer, a preparation method and a personal care product, which have a good effect of reducing the secretion and excretion of sweat, and have anti-fouling, antiperspirant, bactericidal and deodorizing functions, and at the same time have the characteristics of high efficiency, sustained release and long-lasting effect, fast effect, obvious deodorizing effect, not easy to relapse, and has broad application prospects.

[0029] The technical solution of the present invention:

[0030] In one aspect, the present invention provides a composite antiperspirant active polymer, wherein the active substance of the composite antiperspirant active polymer is a combination of green tea extract, mulberry leaf extract and an aluminum-based antiperspirant active substance.

[0031] In some embodiments, the green tea extract includes one or more combinations of green tea polyphenols, green tea caffeine, green tea aromatic oil, and green tea amino acids; preferably, the green tea extract refers to tea polyphenols, which have strong antioxidant and antibacterial properties and can be used as an active ingredient in antiperspirants.

[0032] In some embodiments, the mulberry leaf extract includes one or more combinations of mulberry leaf quercetin, mulberry leaf chlorogenic acid, mulberry leaf alkaloids (1-deoxynojirimycin), and mulberry leaf amino acids (γ-aminobutyric acid); preferably, the mulberry leaf extract refers to mulberry leaf quercetin.

[0033] In some embodiments, the preparation method of the extract comprises: pretreating the raw material, using ethanol aqueous solution as an extraction solvent, mixing it with the raw material, and placing it in an extraction device for stirring and extraction. The extraction temperature is usually controlled at 40-50°C, and the extraction time is 1-2 hours. After the extraction is completed, the solid residue is filtered out, extracted with ethyl acetate, and then rotary evaporated to obtain an extract, which is then purified by column chromatography and dried to obtain an extract. When the raw material is mulberry leaf, a mulberry leaf extract is obtained; when the raw material is green tea, a green tea extract is obtained.

[0034] In some embodiments, the aluminum-based antiperspirant active is of the general formula Al2(OH) x Q y . Hydroxyl halides defined by wH2O, wherein Q represents chlorine, bromine or iodine, x is a variable from 2 to 5, and x+y=6, and wH2O represents a hydrate variable, such as aluminum chlorohydrate.

[0035] In some embodiments, the method for preparing the composite antiperspirant active polymer comprises:

[0036] Step 1. Add a solution containing an aluminum-based antiperspirant active ingredient to an N,N-dimethylformamide (DMF) solution containing a mulberry leaf extract and a green tea extract, and mix well; add ethyl acetate dropwise under stirring, continue stirring at room temperature, wash the formed precipitate with ethanol three times, and ultrasonically disperse it in ethanol to obtain a colloidal solution.

[0037] Step 2. The colloidal solution prepared above is diluted with ethanol, and then an ethanol solution of 1,4-bis(imidazole-1-methyl)benzene and an ethanol solution containing an aluminum-based antiperspirant active substance are alternately added under vigorous stirring at room temperature to obtain a product. The product is recovered by centrifugation, washed with ethanol, and then dried overnight under vacuum conditions to obtain a composite antiperspirant active polymer.

[0038] In some embodiments, the solvent of the solution containing the aluminum-based antiperspirant active is methanol or ethanol, and the concentration of the solution is 0.1-0.5 mol / L.

[0039] In some embodiments, in step 1, the weight ratio of the mulberry leaf extract, the green tea extract and the aluminum-based antiperspirant active is 2-5:1-2:1-3; preferably, the weight ratio of the mulberry leaf extract, the green tea extract and the aluminum-based antiperspirant active is 3-4:1:2-3.

[0040] In some embodiments, in step 2, the volume ratio of the added molar amount of the 1,4-bis(imidazole-1-methyl)benzene and the aluminum-based antiperspirant active substance to the colloidal solution is 0.001-0.01 mol:10 ml.

[0041] In some embodiments, there is no fixed number of alternations. For example, the ethanol solution of 1,4-bis(imidazole-1-methyl)benzene can be added 5 times, and the ethanol solution of the aluminum-based antiperspirant active can be added 5 times, as long as the total amount of the added 1,4-bis(imidazole-1-methyl)benzene and the aluminum-based antiperspirant active meets the above requirements.

[0042] In some embodiments, the concentrations of the ethanol solution of 1,4-bis(imidazole-1-methyl)benzene and the ethanol solution of Zn(NO3)2·6H2O are both 0.01-0.05 mol / L.

[0043] Human sweat is acidic, and the formation and breaking of the coordination bond between the metal and the ligand of the composite antiperspirant active polymer is very sensitive to the change of the pH value of the surrounding environment. The amount of sweat will affect the pH value of the body surface. The coordination bond will be stimulated by the low pH of the surrounding environment and break, first releasing the aluminum-based antiperspirant active substance on the outside, and then releasing the aluminum-based antiperspirant active substance inside after disintegration. When there is no sweat on the body surface, the coordination bond will not break and the aluminum-based antiperspirant active substance will not be released, so as to achieve the purpose of long-term antiperspirant.

[0044] In another aspect, the present invention provides a personal care product that can achieve long-lasting antiperspirant, antiperspirant, bactericidal and deodorant effects. The raw materials of the personal care product include a carrier and a composite antiperspirant active polymer.

[0045] In some embodiments, the carrier can be understood as a solvent, or a chemical substance that can play the role of a solvent. For example, the carrier can be one of isododecane and alkyl benzoate. Alkyl benzoate refers to a low molecular weight ester mixture of benzoic acid and C12-15 alcohol.

[0046] The personal care product can take many suitable forms. For example, according to various aspects, the personal care product is a stick treatment, a body spray, a clear gel, or an aerosol treatment. The personal care product can contain various additional components. For example:

[0047] In some embodiments, the raw materials of the personal care product may further include a moisturizer, and the added weight of the moisturizer may be 0.001 wt%-5 wt% of the total weight of the personal care product.

[0048] In some embodiments, the raw materials of the personal care product may further include an odor trapping agent, and the added weight of the odor trapping agent may be 0.001 wt%-4 wt% of the total weight of the personal care product.

[0049] In some embodiments, the raw materials of the personal care product may also include one or more combinations of solubilizers, buffers, humectants, preservatives, etc. However, it should be noted that the buffer can only be alkaline or neutral to maintain the desired pH of the composition. When the pH is too low and acidic, the bond energy of the composite antiperspirant active polymer will be disconnected, aluminum ions will be released prematurely, and the ability to bind sweat will be lost prematurely.

[0050] Beneficial effects:

[0051] The composite antiperspirant active polymer of the present invention uses natural plant extracts and aluminum-based antiperspirant active substances as composite effective ingredients. Mulberry leaf extract and green tea extract are combined with the aluminum-based antiperspirant active substances. The obtained composite antiperspirant active polymer has no irritation to the skin and releases ligand ions according to the pH value of sweat. The administration site has a significant and long-lasting antiperspirant effect, achieving a satisfactory antiperspirant effect. DETAILED DESCRIPTION

[0052] The present invention will be described below in conjunction with specific embodiments. It should be noted that the following embodiments are examples of the present invention and are only used to illustrate the present invention, but not to limit the present invention. Other combinations and various modifications within the concept of the present invention may be performed without departing from the spirit or scope of the present invention.

[0053] Unless otherwise specified, the chemical reagents used in the present invention are all commercially available analytically pure.

[0054] Preparation of mulberry leaf extract

[0055] Wash the fresh mulberry leaves and dry them at room temperature. Use a grinder to grind the dried mulberry leaves into fine powder. Use 70-80% (v / v) ethanol aqueous solution as the extraction solvent and mix it with mulberry leaf powder. The mixing volume ratio is mulberry leaf: extractant = 1:10. After mixing the mulberry leaf powder with the solvent, put it into the extraction device, control the extraction temperature at 40°C, extract for 2 hours, and stir to extract. After the extraction is completed, filter the solid residue, extract with ethyl acetate, and then rotary evaporate to obtain the extract, which is then purified by column chromatography and dried to obtain mulberry leaf extract.

[0056] Preparation of green tea extract

[0057] Wash the fresh green tea and dry it at room temperature. Use a grinder to grind the dried green tea into fine powder. Use 70-80% (v / v) ethanol aqueous solution as the extraction solvent and mix it with the green tea powder. The mixing volume ratio is green tea: extractant = 1:10. After mixing the green tea powder with the solvent, put it into the extraction device, control the extraction temperature to 40°C, extract for 2 hours, and stir to extract. After the extraction is completed, filter the solid residue, extract with ethyl acetate, and then rotary evaporate to obtain the extract, which is then purified by column chromatography and dried to obtain the green tea extract.

[0058] Preparation of dandelion extract

[0059] Wash fresh dandelions and dry them at room temperature. Use a grinder to grind the dried dandelions into fine powder. Use 70-80% (v / v) ethanol aqueous solution as the extraction solvent and mix it with dandelion powder. The mixing volume ratio is dandelion: extractant = 1:10. After mixing the dandelion powder with the solvent, put it into the extraction device, control the extraction temperature at 40°C, extract for 2 hours, and stir to extract. After the extraction is completed, filter the solid residue, extract with ethyl acetate, and then rotary evaporate to obtain the extract, which is then purified by column chromatography and dried to obtain the dandelion extract.

[0060] Examples and Comparative Examples

[0061] Examples 1-4 and Comparative Examples 5-10 respectively prepare composite antiperspirant active polymers (hereinafter referred to as polymers)

[0062] 1. Dissolve mulberry leaf extract and green tea extract in N,N-dimethylformamide solution, then add 0.2 mol / L aluminum chlorohydrate ethanol solution to the above solution and mix well; add ethyl acetate dropwise under stirring, continue stirring at room temperature, wash the formed precipitate with ethanol for 3 times, and ultrasonically disperse it in ethanol to obtain a colloidal solution.

[0063] 2. Take 10 ml of the colloidal solution prepared above and dilute it with 10 ml of ethanol, then add 0.05 mol / L 1,4-bis(imidazole-1-methyl)benzene ethanol solution and 0.05 mol / L ethanol solution containing aluminum chlorohydrate alternately under vigorous stirring at room temperature to obtain a product. The product is recovered by centrifugation, washed with ethanol, and then dried overnight under vacuum conditions to obtain a polymer.

[0064] The addition amounts of raw materials are shown in Table 1.

[0065] Table 1 Formula for preparing composite antiperspirant active polymer

[0066]

[0067]

[0068] Preparing personal care compositions

[0069] 20 wt % of isododecane, 0.05 wt % of solubilizer PEG-40 hydrogenated castor oil, and 0.05 wt % of moisturizer 1,4-butanediol are sequentially added to one of polymers 1-10 until the weight percentage is 100%, to obtain personal care compositions 1-10 respectively.

[0070] The personal care composition obtained above was tested as follows:

[0071] 1. Antibacterial test: The personal care composition was used to perform antibacterial tests on Staphylococcus aureus and Candida albicans to obtain the inhibition rates of different formulations on different bacterial species, which were calculated based on the lowest bacterial concentration PPM. The lower the value, the more obvious the antibacterial effect.

[0072] 2. Deodorization test: by evaluating the inhibition of different personal care compositions on the intermediate active enzymes (methioninase and uricase) of odor-causing substances;

[0073] 3. Antiperspirant test: 60 subjects with body odor were recruited to measure their body odor levels and the duration of odor elimination. The antiperspirant effect was evaluated by the subjects themselves, and more than 60% of the same evaluation was taken as the evaluation index of this test.

[0074] The test results are shown in Table 2 and Table 3.

[0075] Table 2 Test results of test 1 and test 2

[0076]

[0077]

[0078] Table 3 Test results of test 3

[0079]

[0080] It can be seen from the experimental data in Table 2 that the personal care compositions prepared by Examples 1-3 have obvious effects in the experiments of inhibiting Staphylococcus aureus and Candida albicans, and can inhibit the activities of methioninase and uricase, preventing the enzymes from decomposing sweat to form short-chain fatty acids and ammonia with a special odor.

[0081] The present invention prepares green tea extract, mulberry leaf extract and aluminum-based antiperspirant active substance into a complex polymer, and wraps 1,4-bis(imidazole-1-methyl)benzene as a shell-like structure on the outside of the active substance. When the human body sweats for the first time, the acidity of the sweat destroys the coordination bond of the shell, and the aluminum-based antiperspirant active substance in the shell is first released; as the sweat increases and the acidity of the body fluid increases, the green tea extract, mulberry leaf extract and aluminum-based antiperspirant active substance are gradually released, achieving the purpose of long-term antibacterial and antiperspirant.

[0082] Moreover, during the experiment, the inventors found that the use of mulberry leaf extract and green tea extract in combination with aluminum-based antiperspirant active ingredients can further improve the antibacterial effect. This may be because mulberry leaf extract and green tea extract, as natural antibacterial ingredients, have a relatively complex system, and can synergistically enhance the antibacterial effect when used together.

[0083] The present invention can also have many other embodiments. Without departing from the spirit and essence of the present invention, those skilled in the art can make various corresponding changes and modifications based on the present invention, but these corresponding changes and modifications should all fall within the scope of protection of the claims attached to the present invention.

Claims

1. A composite antiperspirant active polymer, characterized in that: The active substance of the composite antiperspirant active polymer is a combination of green tea extract, mulberry leaf extract and aluminum-based antiperspirant active substance.

2. The composite antiperspirant active polymer according to claim 1, characterized in that: The green tea extract comprises one or more combinations of green tea polyphenols, green tea caffeine, green tea aromatic oil and green tea amino acids.

3. The composite antiperspirant active polymer according to claim 1, characterized in that: The mulberry leaf extract comprises one or more combinations of mulberry leaf quercetin, mulberry leaf chlorogenic acid, mulberry leaf alkaloids and mulberry leaf amino acids.

4. The composite antiperspirant active polymer according to claim 1, characterized in that: The aluminum-based antiperspirant active material is of the general formula Al2(OH) x Q y . Hydroxyl halides defined by wH2O; wherein Q represents chlorine, bromine or iodine, x is a variable from 2 to 5, and x+y=6, and wH2O represents a hydrated variable.

5. The method for preparing the composite antiperspirant active polymer according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1. Add a solution containing an aluminum-based antiperspirant active ingredient to an N,N-dimethylformamide solution containing a mulberry leaf extract and a green tea extract, and mix them evenly; add ethyl acetate dropwise under stirring, continue stirring at room temperature, wash the formed precipitate with ethanol, and ultrasonically disperse it in ethanol to obtain a colloidal solution; Step 2. Dilute the colloidal solution prepared above with ethanol, then alternately add an ethanol solution of 1,4-bis(imidazole-1-methyl)benzene and an ethanol solution containing an aluminum-based antiperspirant active substance under vigorous stirring at room temperature to obtain a product, recover the product by centrifugation, wash it with ethanol, and then dry it under vacuum conditions overnight to obtain a composite antiperspirant active polymer.

6. The method for preparing the composite antiperspirant active polymer according to claim 5, characterized in that: In step 1, the weight ratio of the mulberry leaf extract, the green tea extract and the aluminum-based antiperspirant active is 2-5:1-2:1-3.

7. The method for preparing the composite antiperspirant active polymer according to claim 5, characterized in that: In step 2, the volume ratio of the added molar amount of the 1,4-bis(imidazole-1-methyl)benzene and the aluminum-based antiperspirant active substance to the colloidal solution is 0.001-0.01 mol:10 ml.

8. The method for preparing the composite antiperspirant active polymer according to claim 5, characterized in that: The concentrations of the ethanol solution of 1,4-bis(imidazole-1-methyl)benzene and the ethanol solution containing the aluminum-based antiperspirant active ingredient are both 0.01-0.05 mol / L.

9. A personal care product that can achieve long-lasting antiperspirant, antiperspirant, sterilization and deodorization, characterized in that: The raw materials of the personal care product include a carrier and the composite antiperspirant active polymer according to any one of claims 1 to 4.

10. The personal care product of claim 9, characterized in that The raw materials of the personal care product further include one or more combinations of moisturizers, odor trapping agents, solubilizers, buffers, moisturizers, and preservatives.

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