A device for treating tissue at low temperature

Abstract

The present invention discloses a device for treating tissue at low temperature, comprising a containing component, the containing component is used to contain cryogenic liquid; a spray component, the bottom end of the containing component is connected to the top end of the spray component, the spray component comprises a spray element and a spray shell, the spray element is provided with a first opening, a spray channel and a first vent, the spray element is located inside the spray shell, the first vent is connected to the first opening and the spray channel, the first vent allows gas to pass through, the first opening is used to allow the cryogenic liquid passing through the spray channel to pass out, so as to reduce the temperature of the tissue at the first opening. When in use, the first opening is placed on the tissue to be treated, the cryogenic liquid converges to the tissue at the first opening along the spray channel, the first vent allows gas to pass through, and when the cryogenic liquid contacts the tissue and the gas, it absorbs heat from them and becomes gaseous, so that the temperature of the tissue is rapidly reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to a device for treating tissue at low temperature. Background Art

[0002] Cryogenics refers to the process of using extremely low temperatures to preserve biological tissue or perform medical treatments. The use of cryogenics for medical treatments is mainly used for warts, which are usually wart-like growths on the skin.

[0003] At present, the treatment of tissue (especially wart) is generally to go to the hospital for surgery. Since going to the hospital is troublesome and warts are highly recurrent, they often need to be treated multiple times. In order to solve the above problems, there are methods of using cryotherapy to treat tissue in the prior art, among which portable devices for treating tissue at low temperatures provide a more convenient option. However, when using such devices for treatment, some of them also need to install an applicator, which can often only freeze the surface tissue, and the sprayed cryogenic liquid cannot be well concentrated on the tissue, causing waste inside the device, resulting in poor cooling effect of the tissue.

[0004] To this end, the present invention provides a device for low-temperature treatment of tissue, which can effectively solve the above-mentioned problems, has a better cooling effect, is more convenient to use, is simple to operate and is easy to carry. Summary of the invention

[0005] In order to overcome the deficiencies of the prior art, the present invention provides a device for low-temperature treatment of tissue, which has better cooling effect, is more convenient to use, is simple to operate and is easy to carry.

[0006] The technical solution adopted by the present invention to solve its technical problem is:

[0007] A device for treating tissue at low temperature, comprising:

[0008] A containing assembly, the containing assembly is used to contain the cryogenic liquid;

[0009] A spray assembly, wherein the bottom end of the containing assembly is connected to the top end of the spray assembly, the spray assembly comprises a spray piece and a spray shell, the spray piece is provided with a first opening, a spray channel and a first vent, the spray piece is located inside the spray shell, the first vent is connected to the first opening and the spray channel, the first vent allows gas to pass through, and the first opening is used to allow low-temperature liquid passing through the spray channel to pass out, so as to reduce the tissue temperature at the first opening.

[0010] As an improvement of the present invention, the first vent is arranged close to the first opening, a notch is arranged at the bottom end of the spray shell, and at least a part of the spray element passes through the notch.

[0011] As an improvement of the present invention, a second air vent is provided on the spray member, the second air vent is connected to the spray channel and is away from the first opening and the first air vent, the spray shell is provided with a third air vent, the third air vent is away from the notch, and the second air vent and the third air vent allow the gas in the spray channel to be discharged.

[0012] As an improvement of the present invention, the spray member is used as a slow-release member, and at least part of the slow-release member is inserted into the spray channel.

[0013] As an improvement of the present invention, the containing assembly includes a containing shell and a liquid tank, wherein the liquid tank is inserted into the containing shell, the liquid tank is used to contain the low-temperature liquid, the liquid tank is provided with an outlet, the outlet is arranged toward the top end of the spray channel, and the outlet is used to spray the low-temperature liquid.

[0014] As an improvement of the present invention, a second opening is provided at the bottom end of the accommodating shell, the outlet is connected to the second opening, and the second opening is connected to the spray channel.

[0015] As an improvement of the present invention, the outlet, the second opening, the spray channel and the first opening are coaxially arranged.

[0016] As an improvement of the present invention, the top and bottom ends of the spray shell are respectively provided with a first retaining ring and a second retaining ring, the first retaining ring is clamped to the bottom end of the containing shell, at least part of the spray shell is located inside the containing shell, and the second retaining ring is clamped to the bottom end of the spray shell.

[0017] As an improvement of the present invention, the inner wall of the bottom end of the accommodating shell extends inwardly to form a limiting groove, and the liquid tank is provided with a connecting end, and the connecting end is inserted into the limiting groove.

[0018] As an improvement of the present invention, a second retaining ring is provided at the bottom end of the spray member, and the second retaining ring is clamped at the bottom end of the spray shell.

[0019] As an improvement of the present invention, the connecting end of the liquid tank is provided with a valve, and the valve is used to open or close the outlet.

[0020] The beneficial effect of the present invention is that through the arrangement of the above structure, when in use, the first opening is directly placed on the tissue to be treated, and the bottom of the liquid tank containing the cryogenic liquid is pressed. After the force is applied to the bottom of the tank, a predetermined amount of cryogenic liquid is caused to be discharged from the outlet of the liquid tank and directly converge to the tissue at the first opening along the spray channel. The first vent can discharge gas to reduce the internal pressure of the spray channel. At the same time, the cryogenic liquid, after contacting the gas and tissue, will absorb heat therefrom and begin to evaporate and become gaseous. As evaporation occurs, the temperature of the tissue is reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. The drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0022] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0023] Figure 1 It is a schematic diagram of the overall structure of the first embodiment of the present invention from an angle;

[0024] Figure 2 is a schematic diagram of the overall structure of the first embodiment of the present invention from another angle;

[0025] Figure 3 is a schematic diagram of the explosion structure of the first embodiment of the present invention;

[0026] Figure 4 is a schematic cross-sectional view of a first embodiment of the present invention;

[0027] Figure 5 yes Figure 4 Enlarged view of circle A;

[0028] Figure 6 is a cross-sectional structural schematic diagram of the first embodiment of the present invention in use;

[0029] Figure 7 is a line graph showing changes in tissue temperature versus time after treatment with 100 microliters of dimethyl ether according to the first embodiment of the present invention;

[0030] Figure 8 is a line graph showing changes in tissue temperature versus time after treatment with 200 microliters of dimethyl ether according to the first embodiment of the present invention;

[0031] Fig. 9 is a line graph showing changes in tissue temperature versus time after treatment with 300 microliters of dimethyl ether according to the first embodiment of the present invention;

[0032] Fig.10 is a line graph showing changes in tissue temperature versus time after treatment with 400 microliters of dimethyl ether according to the first embodiment of the present invention;

[0033] Fig.11 is a line graph showing changes in tissue temperature versus time after treatment with 500 microliters of dimethyl ether in the first embodiment;

[0034] Fig.12 is a diagram of low temperature duration after dimethyl ether treatment according to the first embodiment of the present invention;

[0035] Fig.13 is a cross-sectional structural schematic diagram of the second embodiment of the present invention in use state;

[0036] Fig.14 It is a line graph showing the change of tissue temperature over time after treatment with 100 microliters of dimethyl ether according to the second embodiment of the present invention.

[0037] Description of reference numerals:

[0038] 10. Liquid tank; 11. Outlet; 12. Valve; 20. Container shell; 21. Second opening; 22. Limiting groove; 30. Spray element; 31. First opening; 32. Spray channel; 33. First vent; 34. Second vent; 35. Second retaining ring; 36. Sustained release element; 40. Spray shell; 41. Third vent; 42. First retaining ring; 43. Notch; 50. Cryogenic liquid; 60. Tissue. DETAILED DESCRIPTION

[0039] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0040] In the description of the present application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0041] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of this application, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0042] In this application, unless otherwise clearly specified and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0043] In the present application, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0044] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only implementation method.

[0045] Embodiment 1:

[0046] Reference Figures 1 to 12 , a device for low temperature treatment of tissue, comprising:

[0047] A containing assembly, the containing assembly is used to contain the cryogenic liquid 50;

[0048] A spray assembly, wherein the bottom end of the containing assembly is connected to the top end of the spray assembly, the spray assembly comprises a spray element 30 and a spray shell 40, the spray element 30 is provided with a first opening 31, a spray channel 32 and a first vent 33, the spray element 30 is located inside the spray shell 40, the first vent 33 is connected to the first opening 31 and the spray channel 32, the first vent 33 allows gas to pass through, and the first opening 31 is used to allow the low-temperature liquid 50 passing through the spray channel 32 to pass out, so as to reduce the temperature of the tissue 60 at the first opening 31.

[0049] With the above-mentioned structure, when in use, the first opening 31 is directly placed on the tissue 60 to be treated, and a predetermined amount of cryogenic liquid 50 is discharged from the containing assembly and directly converges to the tissue 60 at the first opening 31 along the spray channel 32. After the cryogenic liquid 50 contacts the tissue 60, it absorbs heat from the tissue 60 and evaporates into gas. This process causes the temperature of the tissue 60 to drop rapidly. Due to direct heat transfer, the water in the tissue 60 will freeze to produce ice crystals, thereby destroying the structure of the tissue 60. At the same time, the first vent 33 can not only discharge the gas squeezed by the cryogenic liquid 50 to reduce the pressure in the spray channel 32, but also allow the gas to pass through and contact and mix with the cryogenic liquid 50. After contacting the gas, the cryogenic liquid 50 absorbs heat from the gas and changes into a gaseous state, forming a low-temperature gas-liquid mixture, which reduces the temperature of the tissue 60 and the surrounding environment. Subsequently, the low-temperature gas-liquid mixture contacts the tissue 60 and continues to absorb heat from the tissue 60 to reduce the temperature of the tissue 60, thereby achieving the effect of low-temperature treatment. Preferably, the spray assembly is made of a transparent material. The transparent design allows the user to directly observe the flow and spray status of the cryogenic liquid 50, thereby helping the user to monitor the use of the device in real time.

[0050] In this embodiment, the first vent 33 is arranged close to the first opening 31, and a notch 43 is arranged at the bottom of the spray shell 40, and at least part of the spray element 30 passes through the notch 43. Through the arrangement of the above structure, the first vent 33 is arranged close to the first opening 31. Since the first opening 31 is directly placed on the patient's tissue 60, the first vent 33 can not only discharge the gas squeezed by the cryogenic liquid 50 to reduce the pressure in the spray channel 32, but also can make the gas contact the cryogenic liquid 50, and the cryogenic liquid 50 absorbs the heat in the tissue 60 and the gas to cool the tissue 60. Moreover, due to the arrangement of the first vent 33, the cooling effect of the tissue 60 is more significant. The first vent 33 allows gas to pass through and contact the cryogenic liquid 50. The cryogenic liquid 50 absorbs heat from the gas and evaporates into a gaseous state, which reduces the temperature of the tissue 60 itself and its surrounding environment, forming a low-temperature area. When the cryogenic liquid 50 directly contacts the tissue 60, due to the existence of the low-temperature area, the temperature difference between the tissue 60 and the cryogenic liquid 50 increases, and the heat in the tissue 60 is more easily absorbed by the cryogenic liquid 50, thereby improving the heat transfer efficiency between the tissue 60 and the cryogenic liquid 50. When the device is used to treat the tissue 60, the first opening 31 needs to be placed on the tissue 60. The first opening 31 can better contact the tissue 60 when it passes through the gap 43. If the first opening 31 is set inside the spray shell 40, the tissue 60 cannot contact the first opening 31 well, which may reduce the effect of low-temperature treatment. The first vent 33 allows gas to contact the cryogenic liquid 50 when the cryogenic liquid 50 contacts the tissue 60. At this time, the evaporation of the cryogenic liquid 50 absorbs heat from the skin surface and the surrounding gas, causing the temperature of the tissue 60 to drop rapidly. The cryogenic liquid 50 absorbs heat from the tissue 60 and the gas, which can make the cooling efficiency of the tissue 60 higher. Preferably, the size of the first opening 31 and the size of the patient's tissue 60 can be adapted to each other. The device can select the first opening 31 of various diameters to meet the needs of most patients for cryotherapy of the tissue 60. Preferably, the structure of the spray shell 40 is composed of a cylinder with a wider bottom and a gradually narrowed top, and the top eventually converges into a notch 43, and the shape and size of the notch 43 match the shape and size of the first opening 31.

[0051] In this embodiment, the spray element 30 is provided with a second vent 34, which is connected to the spray channel 32 and is away from the first opening 31 and the first vent 33. The spray shell 40 is provided with a third vent 41, which is away from the notch 43. The second vent 34 and the third vent 41 allow the gas in the spray channel 32 to be discharged. Through the above-mentioned structure, after the cryogenic liquid 50 enters the spray channel 32, part of the cryogenic liquid 50 will evaporate to generate gas. Since the gas previously existing in the spray channel 32 is also squeezed, the second vent 34 is provided to allow the gas to be smoothly discharged from the spray channel 32, and then discharged from the spray shell 40 through the third vent 41. The second vent 34 and the third vent 41 can guide the gas to flow along a predetermined path, avoid excessive evaporation of the cryogenic liquid 50 in unnecessary areas, reduce the waste of the cryogenic liquid 50, and improve the discharge efficiency of the cryogenic liquid 50. At the same time, the internal pressure of the spray channel 32 increased due to the generation of gas is also reduced, thereby extending the service life of the device and ensuring the safety of the user. The third vent 41 is arranged away from the notch 43, and the second vent 34 is arranged away from the first opening 31 and the first vent 33. After the cryogenic liquid 50 enters the spray channel 32, the gas in the spray channel 32 is squeezed and can be discharged through the first vent 33, the second vent 34 and the third vent 41, while ensuring that the cryogenic liquid 50 does not directly contact the second vent 34 and the third vent 41, thereby reducing unnecessary evaporation losses.

[0052] In this embodiment, the containing assembly includes a containing shell 20 and a liquid tank 10, the liquid tank 10 is inserted into the containing shell 20, the liquid tank 10 is used to contain a cryogenic liquid 50, and the liquid tank 10 is provided with an outlet 11, the outlet 11 is arranged toward the top of the spray channel 32, and the outlet 11 is used to spray the cryogenic liquid 50. Through the arrangement of the above structure, the outlet 11 is arranged toward the top of the spray channel 32, and the connection between the outlet 11 and the spray channel 32 can be achieved, so that the cryogenic liquid 50 can be quickly and efficiently transferred from the liquid tank 10 to the spray channel 32, and then delivered to the first opening 31, ensuring the continuity and stability of the low temperature treatment process of the tissue 60. Optionally, the cryogenic liquid 50 is methane, propane, isobutane, n-butane, dimethyl ether, liquid nitrogen or liquid helium. Preferably, dimethyl ether or liquid nitrogen can be used, and dimethyl ether is more preferred. The low boiling point of dimethyl ether enables it to evaporate quickly at room temperature, providing a rapid and controllable cooling effect. This helps to achieve rapid cooling of the tissue 60 while avoiding excessive cooling of the tissue 60. At the same time, the dimethyl ether remains in a liquid state in the liquid tank 10, and the flow rate of the dimethyl ether can be controlled by pressing the bottom of the liquid tank 10 to ensure that the cooling process of the tissue 60 is uniform.

[0053] In this embodiment, the bottom end of the housing 20 is provided with a second opening 21, the outlet 11 is connected to the second opening 21, and the second opening 21 is connected to the spray channel 32. Through the above-mentioned structure, the design of the second opening 21 and the outlet 11 determines the flow path of the cryogenic liquid 50 after it is sprayed out from the liquid tank 10. After the cryogenic liquid 50 is sprayed out, it enters the spray channel 32 from the second opening 21, and then delivers the cryogenic liquid 50 to the first opening 31. Preferably, the sizes of the spray channel 32, the second opening 21 and the outlet 11 match each other, ensuring a close fit between the three, reducing the leakage of the cryogenic liquid 50, and ensuring the sealing and efficiency of the device.

[0054] In this embodiment, the outlet 11, the second opening 21, the spray channel 32 and the first opening 31 are coaxially arranged. Through the above-mentioned structure, the coaxial arrangement allows the cryogenic liquid 50 sprayed through the outlet 11 to directly enter the spray channel 32, be gathered to the first opening 31 in the spray channel 32, and finally stay on the tissue 60 to be cooled. The first opening 31 is in contact with the tissue 60, and the coaxial arrangement has a better effect, which reduces the waste of the cryogenic liquid 50. Preferably, the shape of the spray channel 32 is a cylindrical structure with a streamlined shape, which guides the cryogenic liquid 50 and the cryogenic gas obtained by evaporation of the cryogenic liquid 50 to the first opening 31.

[0055] In this embodiment, the top and bottom of the spray shell 40 are respectively provided with a first retaining ring 42 and a second retaining ring 35, the first retaining ring 42 is clamped to the bottom of the housing shell 20, at least part of the spray shell 40 is located inside the housing shell 20, and the second retaining ring 35 is clamped to the bottom of the spray shell 40. Through the above-mentioned structure, the design of the first retaining ring 42 being clamped to the bottom of the housing shell 20 realizes a stable connection between the spray assembly and the housing shell 20, and at the same time provides convenience for the user to disassemble and assemble the device. Preferably, the bottom of the housing shell 20 is provided with a thread groove, and the first retaining ring 42 is clamped and matched with the thread groove to ensure that the housing shell 20 is firmly connected to the spray assembly when in use. The second retaining ring 35 is used to fix the spray component 30 at the corresponding position of the spray shell 40, and the spray component 30 is detachably located inside the spray shell 40. Such a design allows the user to select the first opening 31 adapted according to the size of different tissues 60, which can meet the needs of different users, and at the same time, the spray component 30 and the spray shell 40 can be easily cleaned when idle.

[0056] In this embodiment, the inner wall of the bottom end of the containing shell 20 extends inward to form a limiting groove 22, and the liquid tank 10 is provided with a connecting end, and the connecting end is inserted into the limiting groove 22. Through the above-mentioned structure, the limiting groove 22 matches the connecting end of the liquid tank 10. This structure ensures that the liquid tank 10 can be firmly placed in the containing shell 20, and at the same time facilitates the user to disassemble and assemble the liquid tank 10 and the containing shell 20. Preferably, the liquid tank 10 is a cylindrical structure, and the top end is designed to be a shape with a gradually decreasing diameter, which helps to achieve a close fit between the liquid tank 10 and the containing shell 20.

[0057] In this embodiment, the connecting end of the liquid tank 10 is provided with a valve 12, and the valve 12 is used to open or close the outlet 11. Through the above-mentioned structure, when in use, the cryogenic liquid 50 is mainly sprayed out and the cryogenic spray and the cryogenic liquid 50 are collected to the patient tissue 60. When in use, the liquid tank 10 containing the cryogenic liquid 50 is inverted in the containing shell 20, the device is held by hand, the first opening 31 is aimed at the patient tissue 60 that needs cryotherapy, and after maintaining a stable state, the bottom of the liquid tank 10 is slowly pressed downward to move the liquid tank 10 downward by about three millimeters. At this time, the valve 12 is squeezed and moves downward by about three millimeters accordingly, so that the cryogenic liquid 50 is sprayed out from the outlet 11 along the second opening 21 into the spray channel 32, and gathers to the first opening 31 in the spray channel 32. At the first opening 31, the cryogenic liquid 50 contacts the patient tissue 60. Then, after the pressing pressure is cancelled, the cryogenic liquid 50 will not be sprayed out. At this time, let the first opening 31 be placed on the patient tissue 60 for a period of time to increase the effect of cryotherapy. This method is repeatable because as long as the same amount of cryogenic liquid 50 is given, the cooling of the patient tissue 60 by the cryogenic liquid 50 is independent of the ambient temperature. Another advantage is that the release of the cryogenic liquid 50 and the application of the cryogenic liquid 50 to the patient tissue 60 do not require additional operations, and the method can achieve the application of the cryogenic liquid 50 to the patient tissue 60 with a single press operation. Preferably, the valve 12 is a metering valve, and each time the metering valve is opened, the liquid tank 10 can spray a predetermined amount of cryogenic liquid 50, and the user can adjust the volume of the predetermined amount of cryogenic liquid 50 sprayed according to their needs.

[0058] In order to demonstrate the effective cooling of the tissue 60 by the device of the present invention, the temperature is measured at different positions of the tissue 60. When in use, the first opening 31 is aligned with the tissue 60, and a predetermined amount of low-temperature liquid 50 is released onto the tissue 60, and the device of the invention is removed at random. Position 1 is defined as the center position of the first opening 31, position 2 is defined as the distance from the first opening 31 to one-half of the outer diameter, position 3 is defined as the edge of the first opening 31, and position 4 is defined as the outside of the first opening 31. The above positions are the positions of the tissue 60 corresponding to the first opening 31. The test material is a piece of pig skin that can simulate artificial skin. First, the assembly with the device according to the present invention is placed on the "wart" through the first opening 31, and then the bottom of the liquid tank 10 containing dimethyl ether is pressed to spray the low-temperature dimethyl ether. The liquid tank 10 uses a 100 microliter quantitative aerosol valve, and the amount sprayed each time is 100 microliters of liquid dimethyl ether.

[0059] The bottom of the liquid tank 10 was pressed once, twice, three times, four times and five times, which were defined as one spray, two sprays, three sprays, four sprays and five sprays, and the volumes of dimethyl ether sprayed were 100 microliters, 200 microliters, 300 microliters, 400 microliters and 500 microliters, respectively. The temperature dropped below the freezing point, causing ice crystals to form in the tissue 60 cells, thereby causing mechanical damage and dehydration of the cells, thereby removing abnormal tissue 60. Figures 7 to 11 As shown, after using the device, the temperature change trends of positions 1, 2 and 3 are the same and the cooling effects are not significantly different. It can be seen that the first opening 31, the first vent 33 and the spray channel 32 have obvious cooling effects on the tissue 60. Fig.12 As shown, the treated tissue 60 is cooled to a temperature below -20°C, and the duration of treatment after using different volumes of dimethyl ether is different. As the volume of dimethyl ether used increases, the duration of positions 1, 2, and 3 below -20°C also increases, but at the same time, the duration of position 4 below 0°C also increases accordingly. In actual use, not only the temperature of the tissue 60 itself should be considered, but also the temperature of the surrounding skin should be considered to avoid injury due to excessively low temperature.

[0060] Embodiment 2:

[0061] Reference Fig.13 and Fig.14 :

[0062] In this embodiment, the spray element 30 is used to accommodate the slow-release element 36, and at least part of the slow-release element 36 is inserted into the spray channel 32. By setting the above structure, the slow-release element 36 is inserted into the spray channel 32. Fig.13As shown, the slow-release member 36 passes through the first opening 31 and directly contacts the tissue 60. Preferably, the slow-release member 36 can be a medical porous material, such as a porous cotton head, etc., which can absorb and store the cryogenic liquid 50 and the cryogenic gas obtained by evaporation, which helps to prolong the action time of the low temperature on the tissue 60, so that the tissue 60 can maintain a lower temperature for a longer time, thereby enhancing the effect of low temperature treatment of the tissue 60. At the same time, due to the structural characteristics of the medical porous material, the gas in the spray channel 32 can also be discharged from the first vent 33, the second vent 34 and the third vent 41 through the medical porous material. In addition, the slow-release member 36 can also serve as a physical barrier to reduce the risk of frostbite that may be caused by the direct contact of the cryogenic liquid 50 with the tissue 60.

[0063] Insert the porous cotton head into the spray channel 32, press the bottom of the liquid tank 10 containing dimethyl ether once to spray out 100 microliters of dimethyl ether, and the dimethyl ether enters the spray channel 32 and is absorbed by the porous cotton head, and the porous cotton head directly contacts the "wart". Fig.14 As shown, after contacting the porous cotton head that has absorbed the cryogenic liquid 50, the temperature of the first, second and third positions dropped significantly, and the temperature remained at about -20°C for a long time. Compared with the first embodiment, in this embodiment, the duration of low temperature at the first, second and third positions increased significantly, and the temperature at the fourth position remained at the initial temperature without significant changes, which can effectively remove wart tissue and prevent the skin of other parts of the patient from being damaged by low temperature.

[0064] As described above, one or more implementation methods are provided in combination with specific contents, and the specific implementation of the present invention is not limited to these descriptions. Any similarity or similarity with the method, structure, etc. of the present invention, or any technical deduction or replacement based on the concept of the present invention, shall be regarded as the protection scope of the present invention.

Claims

1. A device for treating tissue at low temperature, characterized in that: include: A containing assembly, the containing assembly being used to contain a cryogenic liquid (50); A spray assembly, wherein the bottom end of the containing assembly is connected to the top end of the spray assembly, the spray assembly comprises a spray element (30) and a spray shell (40), the spray element (30) is provided with a first opening (31), a spray channel (32) and a first vent (33), the spray element (30) is located inside the spray shell (40), the first vent (33) is connected to the first opening (31) and the spray channel (32), the first vent (33) allows gas to pass through, and the first opening (31) is used to allow low-temperature liquid (50) passing through the spray channel (32) to pass out, so as to reduce the temperature of the tissue (60) at the first opening (31).

2. The device for low temperature treatment of tissue according to claim 1, characterized in that: The first vent (33) is arranged close to the first opening (31), and a notch (43) is provided at the bottom end of the spray shell (40), and at least part of the spray element (30) passes through the notch (43).

3. The device for low temperature treatment of tissue according to claim 1, characterized in that: The spray element (30) is provided with a second vent (34), the second vent (34) is connected to the spray channel (32) and is away from the first opening (31) and the first vent (33); the spray shell (40) is provided with a third vent (41), the third vent (41) is away from the notch (43); the second vent (34) and the third vent (41) allow the gas in the spray channel (32) to be discharged.

4. The device for low temperature treatment of tissue according to claim 1, characterized in that: The spray element (30) is used to accommodate a slow-release element (36), and at least a portion of the slow-release element (36) is inserted into the spray channel (32).

5. The device for low temperature treatment of tissue according to claim 1, characterized in that: The containing assembly comprises a containing shell (20) and a liquid tank (10), wherein the liquid tank (10) is inserted into the containing shell (20), and the liquid tank (10) is used to contain the low-temperature liquid (50). The liquid tank (10) is provided with an outlet (11), and the outlet (11) is arranged toward the top end of the spray channel (32), and the outlet (11) is used to spray out the low-temperature liquid (50).

6. The device for low temperature treatment of tissue according to claim 5, characterized in that: A second opening (21) is provided at the bottom end of the accommodating shell (20), the outlet (11) is connected to the second opening (21), and the second opening (21) is connected to the spray channel (32).

7. The device for low temperature treatment of tissue according to claim 5, characterized in that: The outlet (11), the second opening (21), the spray channel (32) and the first opening (31) are coaxially arranged.

8. The device for low temperature treatment of tissue according to claim 5, characterized in that: A first retaining ring (42) and a second retaining ring (35) are respectively provided at the top and bottom of the spray shell (40); the first retaining ring (42) is retained at the bottom of the accommodating shell (20); at least a portion of the spray shell (40) is located inside the accommodating shell (20); and the second retaining ring (35) is retained at the bottom of the spray shell (40).

9. The device for low temperature treatment of tissue according to claim 5, characterized in that: The inner wall of the bottom end of the containing shell (20) extends inwardly to form a limiting groove (22), and the liquid tank (10) is provided with a connecting end, and the connecting end is inserted into the limiting groove (22).

10. The device for low temperature treatment of tissue according to claim 5, characterized in that: The connection end of the liquid tank (10) is provided with a valve (12), and the valve (12) is used to open or close the outlet (11).

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