A method and system for managing experimental animal resources
By designing the experimental animal resource management system, the problem of insufficient informationization in the existing technology has been solved, the full process management of experimental animal resources and the collaborative management of multiple information has been realized, and the efficient operation and decision-making support capabilities of experimental animal facilities have been improved.
Patent Information
- Application Number
- CN202411832034.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-12
- Publication Date
- 2025-04-04
AI Technical Summary
The existing technology has insufficient informationization in the management of experimental animal resources, and cannot effectively provide decision recommendations for resource management, resulting in insufficient efficiency in resource information query and matching degree confirmation.
An experimental animal resource management system was designed, including basic settings module, space resource management module, animal resource management module, procurement management module, experiment management module, cost management module, instrument and equipment management module and statistical management module. Through the interaction of these modules, the full process management of experimental animal resources is realized.
The digital full-process management of experimental animal resources has been realized, the ability to quickly match resources and business project needs has been improved, the intelligent management of animal health has been enhanced, environmental risk factor analysis and cost management functions have been provided, and the efficient operation of experimental animal facilities has been improved.
Smart Images
Figure CN119761727A_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of experimental animal management, and in particular relates to an experimental animal resource management method and system. Background Art
[0002] With the increasing number of non-clinical studies of innovative drugs in China, large institutions have an increasing demand for visual sharing of experimental animal resources. Realizing efficient use of animal facility resources is an important prerequisite for ensuring cost reduction and efficiency increase in the industry, and it is also a technical problem that major experimental animal centers and facilities urgently need to solve.
[0003] Existing technologies mostly use spreadsheets or a single system to record and share animal facility space and animal resource information. Information integration often relies on switching between different systems and tables. Specialized managers are responsible for secondary data calculation and analysis, and information is transmitted through table sharing or simple display of information within the system. Or it is the management of the entire GLP process, but an independent system is usually used to manage experimental animals and space resources. The management of experimental animals or space resources lacks information interaction with other systems (such as workflow management and big data analysis, etc.). This single system information management method has the defect of insufficient depth of informatization, and cannot directly provide decision recommendations for resource management, help demand personnel quickly realize resource information query and matching confirmation, and make business decisions efficiently.
[0004] Therefore, how to develop a new method and system for experimental animal resource management, how to design the composition of the system and the interaction between the various modules of the system are important issues that need to be urgently addressed in this field. Summary of the invention
[0005] In view of the problems in the prior art, the present invention provides a method and system for managing experimental animal resources.
[0006] An experimental animal resource management system includes a functional module and a database, wherein the functional module includes:
[0007] The basic setting module is configured to set the basic information of the system;
[0008] A space resource management module is configured to manage space use information and approve applications related to space resource use, wherein the applications related to space resource use are selected from space use applications, experimental animal use applications, and test extension applications;
[0009] The animal resource management module is configured to record the information of experimental animals and update the information of experimental animals according to the information synchronized or batch imported from other modules;
[0010] The procurement management module is configured to manage the ordering information of experimental animals, manage the information, audit status and risk rating of suppliers of animals, feeds and bedding, and approve the application for purchasing experimental animals;
[0011] The experiment management module is configured to record the transfer of experimental animals and make application and reservation related to the experiment.
[0012] Preferably, the database is used to store at least one of the following information: information on processes, space resources, animal resources, and equipment.
[0013] Preferably, the management of space usage information includes: entering, real-time updating, summarizing, displaying and querying historical, current and future space usage information within the facility.
[0014] Preferably, the information of the experimental animals includes: experimental animal reception information, individual file information, quarantine management information, and operation information.
[0015] Preferably, the experiment-related applications include: space use application, experimental animal purchase application, experimental animal use application, and experiment extension application; the reservation includes project resource reservation.
[0016] Preferably, at least one of the following modules is also included:
[0017] The cost management module is configured to record the cost usage in the facility, calculate the animal feeding cost in the facility, and analyze the cost usage distribution in the facility;
[0018] The instrument and equipment management module is configured to record instrument and equipment information and calculate equipment usage and matching status;
[0019] The statistics management module is configured to display statistically sorted data according to the set fields, time periods and requirements.
[0020] Preferably, in the cost management module, the cost usage includes facility energy consumption, manpower, feed / litter costs and other cost usage;
[0021] In the instrument and equipment management module, the equipment information includes: equipment name, number, category, quantity, test information, calibration information, verification information, maintenance, fault conditions, and regional distribution;
[0022] In the statistical management module, the data include: data on experimental animals, space, project reservations, equipment, costs, and system usage.
[0023] The present invention also provides a method for managing experimental animal resources, which implements the following process based on the above experimental animal resource management system:
[0024] Step 1: Initiate a project reservation application in the test management module, and after confirming the test information, initiate an application for the use of experimental animals and / or space;
[0025] Or, directly initiate an application for the use of experimental animals and / or space in the experiment management module;
[0026] Step 2: If reserve animals are not used, space use approval is performed in the space resource management module;
[0027] If reserve animals are needed, confirm the information in the animal resource management module. If there are matching animals, select the matching experimental animals. After selection, there is no need to go through space use and animal procurement approval. Just inform the space management staff. If there are no matching animals, continue the process as if reserve animals are not used.
[0028] Step 3: After the space use is approved, the application for the use of experimental animals is approved in the procurement management module and a purchase order is generated;
[0029] Step 4: After confirming that the ordering information is correct in the test management module, complete the animal reception in the animal resource management module and fill in the reception record; if there is any discrepancy with the ordering information, feedback is sent to the procurement management module for the procurement personnel to know or perform abnormal re-purchase;
[0030] Step 5: In the animal resource management module, a quarantine schedule is established for the experimental animals that need to be quarantined, and the quarantine results are entered;
[0031] Step 6: If the experimental animals pass the quarantine, they will enter the experiment. In the animal resource management module, the individual animal information is automatically updated or imported in batches by other systems. If the animals fail the quarantine, the exit operation is performed in the animal resource management module, the selected animal information is no longer updated, and the cage occupied by the selected animal is changed to vacant.
[0032] Step 7: If the experiment ends with death as the endpoint, the experimental animals belonging to the experiment are removed from the experiment in the animal resource management module, the selected animal information is no longer updated, and the cage occupied by the animal is changed to vacant; if the experiment does not end with death, the experimental animals are transferred and changed to reserve animals in the animal resource management module.
[0033] Preferably, in step 1, the experiment leader submits the application for the use of experimental animals and / or the application for the use of space, and the project manager submits the application for project reservation;
[0034] In step 2, the space management personnel will review and approve the use of the space, and the reserve animal manager will confirm whether there are matching animals;
[0035] In step 3, the purchasing staff approves the application for the use of experimental animals;
[0036] In step 4, the experiment leader confirms that the ordering information is correct, and the veterinarian completes the animal admission.
[0037] In step 5, the veterinarian formulates the quarantine schedule and enters the quarantine results;
[0038] In step 7, the space manager will manually exit the room, and the experiment leader will hand over the experimental animals.
[0039] The present invention also provides a computer-readable storage medium, on which is stored: a computer program for implementing the above-mentioned experimental animal resource management system, or a computer program for implementing the above-mentioned experimental animal resource management method.
[0040] The present invention constructs a system and method for the full-process management of experimental animals for the first time. By constructing the modular composition of the system and designing the interaction mode between the modules, the full-process management of experimental animals is combined with the management of other related information and processes, achieving the following beneficial technical effects:
[0041] (1) Digital management of animal facility resources: The system constructed by the present invention collects and integrates resource information such as space, animals, personnel, and equipment of animal facilities, and simultaneously performs big data analysis to achieve rapid matching of resources with business project requirements.
[0042] (2) Supplier management: The present invention can manage important suppliers such as animals and feed / bedding through the system, analyze risks, and accurately rate them, thereby minimizing the introduction of exogenous pollution into the facility.
[0043] (3) Intelligent management of animal health: The system of the present invention can realize the electronic management of animal files and medical records, realize the intelligent management of animal health, establish a powerful health background database, and provide an important basis for project abnormality judgment.
[0044] (4) Environmental risk factor management: In the system of the present invention, the statistical management module is capable of analyzing various risks of facilities through big data and providing managers with risk warnings and risk elimination strategies.
[0045] (5) Cost management: The system of the present invention can analyze the cost of using facility resources, provide budget and cost accounting services, and provide effective data support for project quotations and the finance department and other business departments.
[0046] (6) Equipment management: The system of the present invention can help managers formulate reasonable equipment configuration and maintenance plans by analyzing the configuration quantity, fault information, distribution and other data of the equipment in the facility, and comprehensively grasp the operation and use status of the equipment in the facility.
[0047] (7) Scientific evaluation of facility usage: The system of the present invention can evaluate the annual usage of animal facilities, provide decision support for animal facility management and facility design and construction, and continuously optimize management and improve efficiency based on data.
[0048] In summary, the system and method of the present invention have the advantages of digital full-process management and collaborative management of multiple information, which is conducive to the efficient operation of experimental animal facilities and has a good application prospect.
[0049] Obviously, according to the above contents of the present invention, in accordance with common technical knowledge and customary means in the art, without departing from the above basic technical ideas of the present invention, other various forms of modification, replacement or change may be made.
[0050] The above contents of the present invention are further described in detail below through specific implementation methods in the form of embodiments. However, this should not be understood as the scope of the above subject matter of the present invention being limited to the following examples. All technologies realized based on the above contents of the present invention belong to the scope of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS
[0051] Figure 1 Schematic diagram of the process of the experimental animal resource management method according to Example 1 of the present invention. DETAILED DESCRIPTION
[0052] It should be noted that the algorithms of data collection, transmission, storage and processing steps not specifically described in the embodiments, as well as the hardware structure, circuit connection, etc. not specifically described can all be implemented through the contents disclosed in the prior art.
[0053] Example 1 Experimental Animal Resource Management Method and System
[0054] The system provided in this embodiment includes functional modules and a database, which is used to store information such as processes, space resources, animal resources, equipment, etc., including all work processes and data records generated within this system. These records can be personalized filtered and queried through set fields, and reports can also be exported in a fixed format.
[0055] The functional modules include:
[0056] The basic setting module is configured to set the basic information of the system;
[0057] A space resource management module is configured to manage space use information and approve applications related to space resource use, wherein the applications related to space resource use are selected from space use applications, experimental animal use applications, and test extension applications;
[0058] The animal resource management module is configured to record the information of experimental animals and update the information of experimental animals according to the information synchronized or batch imported from other modules;
[0059] The procurement management module is configured to manage the ordering information of experimental animals, manage the information, audit status and risk rating of suppliers of animals, feeds and bedding, and approve the application for purchasing experimental animals;
[0060] The test management module is configured to record the transfer of experimental animals and submit application and reservation related to the test;
[0061] The cost management module is configured to record the cost usage in the facility, calculate the animal feeding cost in the facility, and analyze the cost usage distribution in the facility;
[0062] The instrument and equipment management module is configured to record instrument and equipment information and calculate equipment usage and matching status;
[0063] The statistics management module is configured to display statistically sorted data according to the set fields, time periods and requirements.
[0064] Among them, the basic setting module setting information includes: system setting, space information setting, animal information setting, test information setting, veterinary work setting, and procurement work setting.
[0065] In the space resource management module, the management of space usage information includes: input, real-time update, aggregation, display and query of historical, current and future space usage information within the facility.
[0066] In the animal resource management module, the experimental animal information recorded and updated includes: experimental animal reception information, individual file information, quarantine management information, and operation information.
[0067] In the experiment management module, the experiment-related applications include: space use application, experimental animal purchase application, experimental animal use application, and experiment extension application; the reservation refers to the project reservation application submitted when the experiment information has not been determined.
[0068] In the cost management module, the cost usage includes facility energy consumption, manpower, feed / litter costs and other cost usage.
[0069] In the instrument and equipment management module, the equipment information includes: equipment name, number, category, quantity, test information, calibration information, verification information, maintenance, fault conditions, and regional distribution.
[0070] In the statistical management module, the data include: data on experimental animals, space, project reservations, equipment, costs, and system usage.
[0071] Methods for using the above system to manage experimental animal resources include: Figure 1 As shown, the specific steps include:
[0072] Step 1: In the experiment management module, when there is experiment confirmation information, the experiment leader directly initiates an application for experimental animal use and / or space use;
[0073] When there is no confirmed test information, the project manager will initiate the project reservation application. After the test information is confirmed, the reservation form will be forwarded to the test leader to complete the animal use application and / or space use application process;
[0074] Step 2: If the reserve animals are not used, in the space resource management module, the space management personnel shall conduct space use approval;
[0075] If reserve animals are needed, in the animal resource management module, the reserve animal manager confirms the information and selects matching experimental animals if there are matching animals (no space use and animal purchase approval is required after selection, only the space manager needs to be notified); if there are no matching animals, the process continues as if reserve animals are not used;
[0076] Step 3: After the space use is approved, in the procurement management module, the procurement personnel approve the application for the use of experimental animals and generate a purchase order;
[0077] Step 4: After the experiment leader confirms that the ordering information is correct in the experiment management module, the veterinarian completes the animal reception in the animal resource management module and fills in the reception record; if there is any discrepancy with the ordering information, the system automatically feeds back to the procurement management module so that the procurement staff can be informed or perform abnormal re-purchase;
[0078] Step 5: In the animal resource management module, the veterinarian formulates a quarantine schedule for the experimental animals that need to be quarantined and enters the quarantine results;
[0079] Step 6: If the experimental animals pass the quarantine, they will enter the experiment. In the animal resource management module, the individual animal information is automatically updated or imported in batches by other systems. If the animals fail the quarantine, the exit operation is performed in the animal resource management module, the selected animal information is no longer updated, and the cage occupied by the selected animal is changed to vacant.
[0080] Step 7: If the experiment ends with death as the endpoint, the experimental animals belonging to the experiment will be automatically removed from the room in the animal resource management module or manually removed by the space management personnel, the selected animal information will no longer be updated, and the cages they occupy will be changed to vacant; if the experiment does not end with death, the experimental animals will be handed over by the experiment leader, and the experimental animals will be changed to reserve animals in the animal resource management module.
[0081] It can be seen from the above embodiments that the system and method provided by the present invention realizes the whole process management of experimental animals, and realizes information sharing and synchronization with other systems, so that the organization can manage experimental animals more efficiently and accurately. Therefore, the present invention has a good application prospect.
Claims
1. An experimental animal resource management system, characterized in that: It includes functional modules and a database, and the functional modules include: The basic setting module is configured to set the basic information of the system; A space resource management module is configured to manage space use information and approve applications related to space resource use, wherein the applications related to space resource use are selected from space use applications, experimental animal use applications, and test extension applications; The animal resource management module is configured to record the information of experimental animals and update the information of experimental animals according to the information synchronized or batch imported from other modules; The procurement management module is configured to manage the ordering information of experimental animals, manage the information, audit status and risk rating of suppliers of animals, feeds and bedding, and approve the application for purchasing experimental animals; The experiment management module is configured to record the transfer of experimental animals and make application and reservation related to the experiment.
2. The experimental animal resource management system according to claim 1, characterized in that: The database is used to store at least one of the following information: information on processes, space resources, animal resources, and equipment.
3. The experimental animal resource management system according to claim 1, characterized in that: The management of space usage information includes: inputting, real-time updating, summarizing, displaying and querying historical, current and future space usage information within the facility.
4. The experimental animal resource management system according to claim 1, characterized in that: The information of the experimental animals includes: experimental animal reception information, individual file information, quarantine management information, and operation information.
5. The experimental animal resource management system according to claim 1, characterized in that: The experiment-related applications include: space use application, experimental animal purchase application, experimental animal use application, and experiment extension application; the reservation includes project resource reservation.
6. The experimental animal resource management system according to claim 1, characterized in that: Also includes at least one of the following modules: The cost management module is configured to record the cost usage in the facility, calculate the animal feeding cost in the facility, and analyze the cost usage distribution in the facility; The instrument and equipment management module is configured to record instrument and equipment information and calculate equipment usage and matching status; The statistics management module is configured to display statistically sorted data according to the set fields, time periods and requirements.
7. The experimental animal resource management system according to claim 6, characterized in that: In the cost management module, the cost usage includes facility energy consumption, manpower, feed / litter costs and other cost usage; In the instrument and equipment management module, the equipment information includes: equipment name, number, category, quantity, test information, calibration information, verification information, maintenance, fault conditions, and regional distribution; In the statistical management module, the data include: data on experimental animals, space, project reservations, equipment, costs, and system usage.
8. A method for managing experimental animal resources, characterized in that: The experimental animal resource management system according to any one of claims 1 to 7 implements the following process: Step 1: Initiate a project reservation application in the test management module, and after confirming the test information, initiate an application for the use of experimental animals and / or space; Or, directly initiate an application for the use of experimental animals and / or space in the experiment management module; Step 2: If reserve animals are not used, space use approval is performed in the space resource management module; If reserve animals are needed, confirm the information in the animal resource management module. If there are matching animals, select the matching experimental animals. After selection, there is no need to go through space use and animal procurement approval. Just inform the space management staff. If there are no matching animals, continue the process as if reserve animals are not used. Step 3: After the space use is approved, the application for the use of experimental animals is approved in the procurement management module and a purchase order is generated; Step 4: After confirming that the ordering information is correct in the test management module, complete the animal reception in the animal resource management module and fill in the reception record; if there is any discrepancy with the ordering information, feedback is sent to the procurement management module for the procurement personnel to know or perform abnormal re-purchase; Step 5: In the animal resource management module, a quarantine schedule is established for the experimental animals that need to be quarantined, and the quarantine results are entered; Step 6: If the experimental animals pass the quarantine, they will enter the experiment. In the animal resource management module, the individual animal information is automatically updated or imported in batches by other systems. If the animals fail the quarantine, the exit operation is performed in the animal resource management module, the selected animal information is no longer updated, and the cage occupied by the selected animal is changed to vacant. Step 7: If the experiment ends with death as the endpoint, the experimental animals belonging to the experiment are removed from the experiment in the animal resource management module, the selected animal information is no longer updated, and the cage occupied by the animal is changed to vacant; if the experiment does not end with death, the experimental animals are transferred and changed to reserve animals in the animal resource management module.
9. The method for managing experimental animal resources according to claim 8, characterized in that: In step 1, the experiment leader submits the application for the use of experimental animals and / or space, and the project manager submits the project reservation application; In step 2, the space management personnel will review and approve the use of the space, and the reserve animal manager will confirm whether there are matching animals; In step 3, the purchasing staff approves the application for the use of experimental animals; In step 4, the experiment leader confirms that the ordering information is correct, and the veterinarian completes the animal admission. In step 5, the veterinarian formulates the quarantine schedule and enters the quarantine results; In step 7, the space manager will manually exit the room, and the experiment leader will hand over the experimental animals.
10. A computer-readable storage medium, characterized in that: Stored thereon are: a computer program for implementing the experimental animal resource management system described in any one of claims 1-7, or a computer program for implementing the experimental animal resource management method described in claim 8 or 9.