A freezing storage device for storing cell samples

By designing a liftable consignment plate and a refrigeration storage device with a driving mechanism, the problem of manually transferring samples during cooling and freezing of cell samples is solved, and the operation efficiency and safety are improved.

CN119778951AInactive Publication Date: 2025-04-08SUZHOU MUNICIPAL HOSPITAL
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Patent Information

Application Number
CN202510063775.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-15
Publication Date
2025-04-08
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

During the cooling and freezing of cell samples, staff need to manually transfer the samples. Two independent freezing devices are increased by increasing the cumbersomeness and difficulty of operation for staff.

Method used

A refrigeration storage device containing multiple consignment plates and a driving mechanism is designed. The consignment plate can be lifted and lowered, and the synchronous drop of the consignment plate is achieved through the driving mechanism, allowing cells to move from the upper temperature zone to the lower temperature zone, reducing the manual transfer step.

Benefits of technology

By reducing manual transfer steps, the operation efficiency of staff is improved, the cooling and freezing process of cell samples is simplified, and the possibility of operation errors is reduced.

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Abstract

The present invention discloses a freezing storage device for storing cell samples, comprising a cabinet, a refrigeration system is arranged at the bottom of the cabinet, and a cold storage cavity is arranged at other positions, and a first evaporator and a second evaporator are arranged in upper and lower distributions on the rear side of the cold storage cavity, and the first evaporator and the second evaporator are connected to the refrigeration system; a plurality of pallet boards are also arranged in the cold storage cavity, and the plurality of pallet boards are divided into a plurality of groups distributed in upper and lower distributions, and two pallet boards are arranged in each group; an isolation plate is arranged between two pallet boards in the same group; the present invention arranges a refrigeration system below the cabinet, and a first evaporator and a second evaporator are arranged in upper and lower distributions in the cabinet, and the first evaporator and the second evaporator are connected to the refrigeration system through an electromagnetic valve, and the flow rate, evaporation temperature and other parameters of the refrigerant in each evaporator area are controlled by the electromagnetic valve, so that different parts of the evaporator produce different refrigeration effects, and corresponding temperature zones with different temperatures are created.
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Description

Technical Field

[0001] The invention relates to the field of cell freezing equipment, in particular to a freezing storage device for storing cell samples. Background Art

[0002] In basic research fields such as cell biology and molecular biology, many experiments require the use of specific types of cells to explore the physiological functions, metabolic processes, signal transduction mechanisms, etc. of cells. For some difficult diseases, doctors may need to perform multiple tests and analyses on the patient's cell samples (such as blood cells, diseased tissue cells, etc.) to diagnose the disease, evaluate disease progression, and monitor treatment effects. Therefore, by freezing and preserving cell samples, retrospective testing can be performed at different time points to achieve more accurate disease diagnosis and dynamic monitoring of the disease, or to conduct repeated experiments.

[0003] Cryopreservation of cell samples requires cell preparation, cryoprotectant addition, cell packaging, cooling and freezing, and long-term storage in liquid nitrogen. During the cooling and freezing operation, the cell samples are generally placed in a refrigerator at minus 40 degrees to cool down, and then placed in a refrigerator at minus 80 degrees for freezing and preservation, so as to achieve slow cooling of the cells and reduce the damage to the cells caused by ice crystal formation.

[0004] At present, there are many types of refrigerators used for cooling and freezing. For example, a Chinese patent with publication number CN213535623U discloses a cell storage and freezing device, which includes a box body and a box door connected to the box body in an openable and closable manner, and an observation window is provided on the box door; the inner wall of the box body is provided with a plurality of groups of slide grooves, and the placement plates are correspondingly slidably arranged in the slide grooves; each placement plate is provided with a plurality of placement grooves, and the placement plates are also provided with a plurality of through holes between the edge and the placement grooves; the inner wall of the box body is also fixed with a plurality of lighting lamp holders, and each lighting lamp holder is equipped with a lighting lamp; a refrigerator is provided at the bottom of the box body, and the refrigerator is connected to a cooling pipe, and the cooling pipe is arranged in the box body. This kind of cell storage and freezing device can effectively solve the problems of poor storage and freezing effect of existing cell storage racks, chaotic cell storage areas, different cells stored together, inconvenience in taking out and storing cells, and disadvantageous for popularization and use, and has high practical value.

[0005] When using the freezing device provided by the above patent, or other types of freezing devices to achieve cooling and freezing of cell samples, two freezing devices are required. Since the two freezing devices are independently distributed, the staff is required to transfer the cell samples between the two refrigeration devices, which increases the tediousness of the staff. If this step can be omitted, it will be beneficial for the staff to work efficiently. Summary of the invention

[0006] The purpose of the present invention is to provide a freezing storage device for storing cell samples, aiming to improve the problem that workers need to transfer samples during the cell cooling and freezing process.

[0007] The present invention is implemented as follows: a freezing storage device for storing cell samples includes a cabinet, a refrigeration system is arranged at the bottom of the cabinet, and a cold storage cavity is arranged at the remaining position, and a first evaporator and a second evaporator are arranged on the upper and lower sides of the rear side of the cold storage cavity, and the first evaporator and the second evaporator are connected to the refrigeration system; a plurality of pallet plates are also arranged in the cold storage cavity, and the plurality of pallet plates are evenly divided into a plurality of groups distributed up and down, and two pallet plates are arranged in each group; an isolation plate is arranged between the two pallet plates in the same group, and the isolation plate divides the cold storage cavity, and a driving mechanism is arranged on the edge, and the driving mechanism can control the lifting and lowering of the plurality of groups of isolation plates.

[0008] Preferably, a dividing plate is provided on the front side of the cold storage cavity, and a partition is provided on the inner side wall. The partition is in sliding contact with the pallet plate. The dividing plate is in a horizontal state and is always opposite to a certain group of pallet plates, thereby dividing the cold storage cavity into two upper and lower temperature zones.

[0009] Preferably, each shipping board includes a main board and a first thermal insulation layer, two first thermal insulation layers are provided, and the two first thermal insulation layers are distributed on the upper and lower sides of the main board; a groove is provided on the upper first thermal insulation layer.

[0010] Preferably, snap grooves are provided on two opposite vertical side walls of the isolation plate, the snap grooves are provided along the height direction of the isolation plate, and the ends are provided as openings, and snap plates are fixedly provided at the ends of two main boards in the same group that are close to each other, and the snap plates are installed in the snap grooves.

[0011] Preferably, entry and exit grooves are provided on two opposite vertical side walls of the isolation plate. The entry and exit grooves are provided along the width direction of the isolation plate, and the ends are also provided as openings and are communicated with the snap grooves. The snap plate can pass through the entry and exit grooves.

[0012] Preferably, the driving mechanism includes a first driving device and a second driving device that are staggered, and the first driving device and the second driving device both include an annular belt and a clamping plate. Multiple clamping plates are evenly distributed along the circumference direction of the annular belt and fixedly connected to the annular belt; a second insulation layer is provided on the upper and lower sides of each clamping plate.

[0013] Preferably, a first wheel body is provided at both ends of one annular belt, and a second wheel body is provided at both ends of the other annular belt. The first wheel body is installed at the end of the support shaft, and the second wheel body is installed at the end of the support tube. The support shaft is connected through the support tube through a bearing.

[0014] Preferably, the support tube passes through the cabinet and is connected to the cabinet through a bearing seat. Sprockets are provided at the ends of the support tube and the ends of the support shaft. Two motors are provided at the bottom of the cabinet. The sprockets of the two motors are connected to the sprockets of the support tube and the support shaft through chains.

[0015] Preferably, the driving mechanism is sleeved on the outer side of the side plate, and the side plate is fixedly connected to the isolation plate; the second notch and the first notch are respectively provided on the main board and the first insulation layer, the length of the second notch is half of the length of the first notch, and the second notches of the two main boards in the same group are staggered; the card plates of the first driving device and the second driving device both extend into the first notch, and one card plate is sleeved on the main board, while the other card plate is arranged opposite to the second notch.

[0016] Preferably, a supporting plate is arranged between the bottom of the isolation plate and the bottom plate of the cold storage cavity, an insert plate is arranged above the supporting plate, and second magnets are arranged at the lower end corners, the insert plate is inserted into the isolation plate, and the second magnet repels and faces the first magnet at the bottom of the cold storage cavity; a push plate is arranged at the bottom of the isolation plate, the push plate is installed at the end of the second telescopic cylinder, and the second telescopic cylinder is arranged through the cabinet.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] 1. The present invention sets a refrigeration system under the cabinet, and sets a first evaporator and a second evaporator in the upper and lower parts of the cabinet, and the first evaporator and the second evaporator are connected to the refrigeration system through solenoid valves. The solenoid valves are used to control the flow rate, evaporation temperature and other parameters of the refrigerant in each evaporator area, so that different parts of the evaporator produce different refrigeration effects, thereby creating corresponding temperature zones with different temperatures.

[0019] 2. The present invention is provided with a transport plate, which can support the cell tube rack in a stable manner in a certain temperature zone, and can move the cells located in the upper temperature zone to the lower temperature zone according to needs, so as to achieve cooling and freezing treatment, and changes the current situation in which two freezing devices are provided and workers are required to transfer cells.

[0020] 3. The present invention is provided with a driving mechanism, under the action of which the carrying plate can be controlled to descend, and the carrying plates located on both sides of the isolation plate can be controlled to descend synchronously, so as to facilitate the movement of cells from the upper temperature zone to the lower temperature zone. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a first structural schematic diagram of the present invention as a whole;

[0022] Figure 2 It is a second structural schematic diagram of the present invention as a whole;

[0023] Figure 3 It is a first structural schematic diagram of the cabinet of the present invention;

[0024] Figure 4 is a second structural schematic diagram of the cabinet of the present invention;

[0025] Figure 5 It is a first structural schematic diagram of the carrier plate, the isolation plate, and the driving mechanism of the present invention;

[0026] Figure 6 is a first structural schematic diagram of the isolation plate of the present invention;

[0027] Figure 7 It is a structural schematic diagram of the driving mechanism of the present invention;

[0028] Figure 8 is a schematic structural diagram of the first driving device of the present invention;

[0029] Fig. 9 It is a structural schematic diagram of a shipping plate of the present invention;

[0030] Fig.10 It is a schematic structural diagram of two shipping plates of the present invention;

[0031] Fig.11 It is a structural schematic diagram of the supporting plate of the present invention;

[0032] Fig.12 It is a structural schematic diagram of the braking mechanism of the present invention.

[0033] Fig.13 It is a structural schematic diagram of the second carrying plate, the isolation plate and the driving mechanism of the present invention;

[0034] Fig.14 2 is a second structural schematic diagram of the isolation plate of the present invention.

[0035] In the figure: 1. cabinet; 11. refrigeration system; 12. brake mechanism; 121. first telescopic cylinder; 122. brake plate; 13. partition; 14. partition plate; 15. first evaporator; 16. second evaporator; 17. first magnet; 2. carriage plate; 21. snap plate; 22. first insulation layer; 23. main board; 24. first missing groove; 25. second missing groove; 3. isolation plate; 31. snap groove; 32. inlet and outlet groove; 33. side plate; 4. supporting plate; 41. second magnet; 42. plug plate; 5. push plate; 51. second telescopic cylinder; 6. driving mechanism; 61. first driving device; 611. annular belt; 612. second insulation layer; 613. snap plate; 62. second driving device; 63. first wheel body; 64. second wheel body; 65. support pipe; 66. support shaft. DETAILED DESCRIPTION

[0036] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0037] The following is a further description with reference to the accompanying drawings and specific embodiments:

[0038] Example 1

[0039] like Figure 1-4 As shown, in order to reduce the manual involvement in the cooling and freezing process, this embodiment provides a new freezing device, the cold storage chamber of which is provided with two different temperature zones, namely, the temperature zone of minus 40 degrees and the temperature zone of minus 80 degrees, and the two temperature zones are distributed up and down. A transfer and shipping component is provided in the two temperature zones, which can stably support the cell cryopreservation tube rack and control the lifting and lowering of the cell cryopreservation tube rack, thereby moving the cells in the upper temperature zone to the lower temperature zone, changing the current situation where two freezing devices are provided and workers are required to transfer cells.

[0040] Specifically, the freezing device includes a cabinet 1, which mainly includes a cold storage cavity, and a refrigeration system 11 is arranged below the cold storage cavity, and a first evaporator 15 and a second evaporator 16 are arranged on the upper and lower sides of the rear side of the cold storage cavity. The first evaporator 15 and the second evaporator 16 are connected to the refrigeration system 11 through a solenoid valve (such as a pilot solenoid valve). Therefore, the solenoid valve can be used to control the flow rate, evaporation temperature and other parameters of the refrigerant in each evaporator area, so that different parts of the evaporator produce different refrigeration effects, thereby correspondingly creating temperature zones with different temperatures. An insulation layer is arranged on the side wall of the cold storage cavity to reduce the heat exchange between the inside of the device and the external environment. A cabinet door is arranged on the front side of the cabinet 1. The connection between the cabinet door and the cabinet 1 refers to the setting of a refrigerator, and a button can be arranged on the cabinet door.

[0041] The above-mentioned refrigeration system 11 is a prior art, which is briefly introduced here. It mainly includes a compressor, a condenser, a throttling device, etc. The compressor compresses the refrigerant gas to increase its pressure and temperature, thereby providing power for the refrigeration cycle. Commonly used compressors in low-temperature refrigerators include piston type, vortex type, etc. The main function of the condenser is to cool the high-temperature, high-pressure refrigerant gas discharged from the compressor so that it condenses into a liquid. The types of condensers include air-cooled type, water-cooled type, etc. The throttling device can be set to be like a capillary tube, an expansion valve, etc., and its function is to throttle and reduce the pressure of the refrigerant, so that the refrigerant changes from a high-pressure liquid to a low-pressure liquid, and the temperature also decreases accordingly, creating conditions for the refrigeration of the evaporator, and can control the flow of the refrigerant, thereby affecting the refrigeration effect and temperature regulation.

[0042] A temperature control system can also be set up in the device, and the stability control system has also been publicly used. Here is a brief introduction. It includes temperature sensors, controllers, etc. The temperature sensor is installed in two temperature zones to monitor the temperature changes in the temperature zones in real time and feed back the temperature signal to the controller. Common temperature sensors include thermistors, thermocouples, etc. The controller (such as PLC, MCU, etc.) receives the feedback signal from the temperature sensor and then regulates the refrigeration system according to the preset temperature value. For example, when the temperature is higher than the set temperature, the controller will control the compressor to start or adjust its operating frequency, so that the refrigeration system increases the refrigeration force and causes the temperature to drop; when the temperature approaches or reaches the set temperature, the refrigeration system is adjusted to maintain it near the set temperature to ensure the stability of the temperature. Some advanced controllers can also realize remote monitoring, temperature curve recording and other functions. The solenoid valve is electrically connected to the controller, and the flow of the refrigerant can be controlled by the controller, which provides convenience for manufacturing different temperature zones.

[0043] Example 2

[0044] like Figure 5 As shown, on the basis of Example 1, in order to realize the movement of cells from the upper temperature zone to the lower temperature zone, the transfer and shipping assembly includes an isolation plate 3, a driving mechanism 6, a plurality of shipping plates 2, etc. The isolation plate 3 is arranged along the height direction of the cold storage cavity, and is arranged in the middle of the cold storage cavity. The plurality of shipping plates 2 are evenly arranged on both sides of the isolation plate 3, and are evenly distributed along the height direction of the isolation plate 3. The driving mechanism 6 is arranged on the rear edge of the isolation plate 3, and the two shipping plates 2 on the same surface are connected to the driving mechanism 6, and can be synchronously lifted and lowered under the action of the driving mechanism 6. Therefore, after the cell cryopreservation tube rack is embedded in the groove of the shipping plate 2, the shipping plate 2 can be controlled under the action of the driving mechanism 6 to drive the cell cryopreservation tube rack to lift and lower.

[0045] like Figure 3 , Fig. 9As shown, in order to achieve the separation of the upper and lower temperature zones, each pallet 2 includes a main board 23 and a first insulation layer 22. Two first insulation layers 22 are provided, and the two first insulation layers 22 are distributed on the upper and lower sides of the main board 23. Therefore, the insulation layer reduces the heat exchange between the upper and lower temperature zones, which helps to maintain the stability of the internal temperature. A dividing plate 14 is provided on the front side of the cold storage cavity, and a partition 13 is provided on the inner side wall. The partition 13 is in sliding contact with the pallet 2. The dividing plate 14 is in a horizontal state and is always facing a group of pallet 2. Therefore, under the action of the pallet 2, the heat transfer between the upper and lower temperature zones can be effectively isolated.

[0046] like Fig. 9 As shown, in order to stably install the cell freezing tube rack relative to the transport plate 2, a groove is provided on the upper first insulation layer 22, and the bottom of the cell freezing tube rack is inserted into the groove.

[0047] like Figure 6 , Fig. 9 As shown, in order to make the main board 23 stably and movably installed relative to the isolation board 3, snap grooves 31 are provided on the two opposite vertical side walls of the isolation board 3. The snap grooves 31 are provided along the height direction of the isolation board 3, and the ends are provided as openings. In the same group, snap plates 21 are fixedly provided at the ends close to each other. The snap plates 21 are installed in the snap grooves 31. With the cooperation of the snap plates 21 and the snap grooves 31, the main board 23 is stably installed relative to the isolation board 3, and it is convenient for the main board 23 to move along the height direction of the isolation board 3.

[0048] like Figure 6 As shown, in order to facilitate the staff to install the pallet board 2 on the side of the isolation board 3 and to be able to disassemble the pallet board 2 as needed, entry and exit grooves 32 are provided at the upper and lower ends of the two vertical side walls of the isolation board 3. The entry and exit grooves 32 are arranged along the width direction of the isolation board 3, and the ends are also arranged to be open, and at the same time are arranged to communicate with the snap grooves 31. The size of the entry and exit grooves 32 is larger than the size of the snap plate 21. Therefore, the snap plate 21 can enter and exit the snap grooves 31 through the entry and exit grooves 32.

[0049] like Figure 7 , Figure 8As shown, in order to control the lifting of the pallet 2, the driving mechanism 6 includes a first driving device 61, a second driving device 62, two first wheels 63, a second wheel 64, etc. The first driving device 61 and the second driving device 62 are arranged in front and rear lateral positions, and both include an annular belt 611 and a clamping plate 613. A second insulation layer 612 is arranged on both the upper and lower sides of each clamping plate 613, and a plurality of clamping plates 613 are evenly distributed along the circumference direction of the annular belt 611 and are fixedly connected to the annular belt 611. The annular belt 611 is sleeved on the outer side of the side plate 33, and the side plate 33 is fixedly connected to the isolation plate 3. The first wheel body 63 is respectively provided at both ends of one annular belt 611, and the second wheel body 64 is respectively provided at both ends of the other annular belt 611. The first wheel body 63 is installed at the end of the support shaft 66, and the second wheel body 64 is installed at the end of the support tube 65. The support shaft 66 is connected through the support tube 65 through a bearing. Therefore, with the cooperation of the support tube 65, the support shaft 66 and the wheel body, the stable installation of the first annular belt 611 is achieved, so as to provide support for controlling the rotation of the annular belt 611 under the action of external force to force the clamping plate 613 to move.

[0050] like Figure 2 , Figure 7 As shown, in order to control the rotation of the annular belt 611, the support tube 65 passes through the cabinet 1 and is connected to the cabinet 1 through a bearing seat. Sprockets are provided at the ends of the support tube 65 and the ends of the support shaft 66. Two motors (which can be set as servo motors, stepper motors, etc.) are provided at the bottom of the cabinet 1. The sprockets of the two motors are connected to the sprockets of the support tube 65 and the support shaft 66 through chains. Therefore, the two motors can control the two annular belts 611 to rotate in opposite directions. Or in the case of setting one motor, two bevel gears and an intermediate gear are used for power transmission between the support tube 65 and the support shaft 66. The intermediate gear is located between the other bevel gears. The two bevel gears are respectively installed on the support tube 65 and the support shaft 66, thereby making the two annular belts 611 rotate in opposite directions. The opposite rotation of the two annular belts 611 can control the synchronous descent of the carrier plates 2 located on both sides of the isolation plate 3, thereby making the cells carried by them move from the upper temperature zone to the lower temperature zone. The wheel body and the annular belt can be set as a synchronous wheel and a synchronous belt.

[0051] like Figure 2 , Fig.12 As shown, in order to make the stopped endless belt 611 stationary, a brake mechanism 12 is provided at the end of the other support tube 65 and the end of the support shaft 66. The brake mechanism 12 includes a first telescopic cylinder 121 and a brake plate 122. The brake plate 122 is installed at the end of the first telescopic cylinder 121, and the brake plate 122 can be controlled to fit the support tube 65 and the support shaft 66 under the action of the first telescopic cylinder 121, so as to achieve the braking of the support tube 65 and the support shaft 66, so as to stably install the transporting plate 2. The telescopic cylinder can be set as an electric cylinder.

[0052] like Fig. 9 , Fig.10 As shown, in order to enable the driving mechanism 6 to control the pallet 2 to descend, the main board 23 and the first insulation layer 22 are respectively provided with a second notch 25 and a first notch 24, the length of the second notch 25 is half the length of the first notch 24, and the second notches 25 of the same group of two main boards 23 are staggered. The two card plates 613 located on the same surface of the first driving device 61 and the second driving device 62 both extend into the first notch 24, and one card plate 613 is sleeved on the main board 23, while the other card plate 613 is arranged opposite to the second notch 25, so that when the two annular belts 611 rotate in opposite directions, the main boards 23 located on both sides can be controlled to descend synchronously.

[0053] Example 3

[0054] like Figure 5 As shown, on the basis of Example 2, in order to enable the pallet plate 2 moved to the bottom of the isolation plate 3 to be separated from the driving mechanism 6, a push plate 5 is provided at the bottom of the isolation plate 3, and the push plate 5 is installed at the end of the second telescopic cylinder 51. The second telescopic cylinder 51 is arranged through the cabinet 1, so that under the action of the second telescopic cylinder 51, the push plate 5 can be controlled to move, and then under the action of the push plate 5, the pallet plate 2 directly opposite to it is forced to be arranged along the width direction of the isolation plate 3, that is, the snap plate 21 moves in the entry and exit groove 32 until the main board 23 is separated from the connection with the snap plate 613.

[0055] like Fig.13 , Fig.14 As shown, in order to facilitate the next transporting plate 2 to be separated from the driving mechanism 6, the buckle slot 31 is provided in two parts, the two parts of the buckle slot 31 are staggered and arranged in communication with the lower inlet and outlet slot 32. Then, under the action of the second telescopic cylinder 51, the buckle plate 21 can be moved into the lower buckle slot 31 under the action of the push plate 5, and fall along the lower buckle slot 31 under the action of gravity.

[0056] like Figure 3 , Fig.13 As shown, in order to avoid collision during the falling process of the carrying plate 2, a supporting plate 4 is arranged between the bottom of the isolation plate 3 and the bottom plate of the cold storage cavity, an insert plate 42 is arranged above the supporting plate 4, and a second magnet 41 is arranged at the lower end corner, and the insert plate 42 is inserted into the isolation plate 3 to realize stable and movable installation of the supporting plate 4. The second magnet 41 repels and faces the first magnet 17 at the bottom of the cold storage cavity. Under the condition of controlling the supporting plate 4 to always have an upward trend, it can provide support for the supporting plate 4 to descend when it is subjected to external force.

[0057] The telescopic cylinder and the motor are connected to the corresponding ports of the controller (such as PLC, MCU) through cables. For the motor, the power line and the encoder feedback line must be connected; for the electric cylinder, the power line that drives its telescopic action and the feedback line of the built-in displacement sensor must be connected to ensure that the controller can achieve effective electrical signal transmission between the motor and the electric cylinder. According to the communication protocols supported by the motor and the electric cylinder themselves (such as the common Modbus, CANopen, etc.), the corresponding communication protocol configuration is performed on the controller so that the controller can identify and parse the status feedback information from the motor and the electric cylinder, and can also accurately send control instructions to them to achieve two-way communication. Under the above settings, the collaborative work logic can be realized through the control program of the controller, and support can be provided for the pallet plate 2 to detach from the drive mechanism 6 when the pallet plate 2 is controlled to descend for a preset period.

[0058] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A freezing storage device for storing cell samples, characterized in that: The invention comprises a cabinet (1), a refrigeration system (11) is arranged at the bottom of the cabinet (1), and a cold storage cavity is arranged at the remaining position, and a first evaporator (15) and a second evaporator (16) are arranged on the upper and lower sides of the rear side of the cold storage cavity, and the first evaporator (15) and the second evaporator (16) are connected to the refrigeration system (11); a plurality of pallet boards (2) are also arranged in the cold storage cavity, and the plurality of pallet boards (2) are evenly divided into a plurality of groups distributed in the upper and lower sides, and two pallet boards (2) are arranged in each group; an isolation board (3) is arranged between the two pallet boards (2) in the same group, and the isolation board (3) divides the cold storage cavity, and a driving mechanism (6) is arranged at the edge, and the driving mechanism (6) can control the lifting and lowering of the plurality of groups of isolation boards (3).

2. A freezing storage device for storing cell samples according to claim 1, characterized in that: A dividing plate (14) is arranged on the front side of the cold storage cavity, and a partition (13) is arranged on the inner side wall. The partition (13) is in sliding contact with the pallet (2). The dividing plate (14) is in a horizontal state and is always directly opposite to a group of pallet (2), thereby dividing the cold storage cavity into two upper and lower temperature zones.

3. A freezing storage device for storing cell samples according to claim 1, characterized in that: Each of the pallet boards (2) comprises a main board (23) and a first thermal insulation layer (22); two first thermal insulation layers (22) are provided, and the two first thermal insulation layers (22) are distributed on the upper and lower sides of the main board (23); and a groove is provided on the upper side of the first thermal insulation layer (22).

4. A freezing storage device for storing cell samples according to claim 3, characterized in that: Snap grooves (31) are provided on two opposite vertical side walls of the isolation plate (3); the snap grooves (31) are provided along the height direction of the isolation plate (3) and the ends are provided as openings; snap plates (21) are fixedly provided at the ends of the two main plates (23) in the same group that are close to each other, and the snap plates (21) are installed in the snap grooves (31).

5. A freezing storage device for storing cell samples according to claim 4, characterized in that: Entry and exit grooves (32) are arranged on two opposite vertical side walls of the isolation plate (3). The entry and exit grooves (32) are arranged along the width direction of the isolation plate (3), and the ends are also arranged to be open. At the same time, they are arranged to communicate with the buckle grooves (31), and the buckle plate (21) can pass through the entry and exit grooves (32).

6. A freezing storage device for storing cell samples according to claim 3, characterized in that: The driving mechanism (6) comprises a first driving device (61) and a second driving device (62) which are staggered in distribution; the first driving device (61) and the second driving device (62) both comprise an annular belt (611) and a clamping plate (613); a plurality of the clamping plates (613) are evenly distributed along the circumference direction of the annular belt (611) and are fixedly connected to the annular belt (611); and a second thermal insulation layer (612) is provided on the upper and lower sides of each of the clamping plates (613).

7. A freezing storage device for storing cell samples according to claim 6, characterized in that: A first wheel body (63) is respectively provided at both ends of one of the annular belts (611), and a second wheel body (64) is respectively provided at both ends of the other annular belt (611). The first wheel body (63) is installed at the end of a support shaft (66), and the second wheel body (64) is installed at the end of a support tube (65). The support shaft (66) is connected to the support tube (65) through a bearing.

8. A freezing storage device for storing cell samples according to claim 7, characterized in that: The support tube (65) is arranged to penetrate the cabinet (1) and is connected to the cabinet (1) via a bearing seat. Sprockets are arranged at the ends of the support tube (65) and the ends of the support shaft (66). Two motors are arranged at the bottom of the cabinet (1). The sprockets of the two motors are connected to the sprockets of the support tube (65) and the support shaft (66) via chains.

9. A freezing storage device for storing cell samples according to claim 7, characterized in that: The driving mechanism (6) is sleeved on the outer side of the side plate (33), and the side plate (33) is fixedly connected to the isolation plate (3); the main board (23) and the first insulation layer (22) are respectively provided with a second notch (25) and a first notch (24), the length of the second notch (25) is half the length of the first notch (24), and the second notches (25) of the two main boards (23) in the same group are staggered; the clamping plates (613) of the first driving device (61) and the second driving device (62) both extend into the first notch (24), and one clamping plate (613) is sleeved on the main board (23), while the other clamping plate (613) is arranged opposite to the second notch (25).

10. A freezing storage device for storing cell samples according to claim 7, characterized in that: A supporting plate (4) is arranged between the bottom of the isolation plate (3) and the bottom plate of the cold storage cavity; an inserting plate (42) is arranged above the supporting plate (4), and second magnets (41) are arranged at the lower end corners; the inserting plate (42) is inserted into the isolation plate (3); the second magnet (41) and the first magnet (17) at the bottom of the cold storage cavity are repelled and face each other; a push plate (5) is arranged at the bottom of the isolation plate (3); the push plate (5) is mounted at the end of a second telescopic cylinder (51); and the second telescopic cylinder (51) is arranged to penetrate the cabinet (1).

Citation Information

Patent Citations

  • Cell storage and cryopreservation device

    CN213535623U