Portable large-view-field fundus camera optical system

Abstract

The invention relates to a portable large-view-field fundus camera optical system, which adopts a four-piece lens as a retina objective lens, an improved Gaussian lens group as an imaging lens group and secondary imaging, retina is imaged at the center of the system through the retina objective lens, and a central image is finally imaged on a CMOS (complementary metal oxide semiconductor) sensor through a focusing lens group and the imaging lens group. And finally, a clear eye fundus image is obtained. And meanwhile, a plano-concave lens is used as a focusing lens in the Gaussian lens group. The system is simple in optical design structure and low in manufacturing cost, compared with a portable fundus camera in the market, the number of lenses is smaller, the requirements of large view field and large-range focusing can be met without an aspherical mirror, the length of the system is smaller than 190 mm, and the portable requirement is met.

Description

Technical Field

[0001] The invention relates to the field of ophthalmic optical instruments, and in particular to a portable large-field-of-view fundus camera optical system. Background Art

[0002] As the only tissue in the body that can observe blood vessels and their distribution in living, non-invasive conditions, the retina has become an important window for diagnosing eye diseases and related systemic diseases. The most common ophthalmic diseases are cataracts, glaucoma, conjunctivitis, etc. In addition to ophthalmic lesions characterized by appearance, retinal capillary lesions can be used for early diagnosis of hypertension, diabetes, thrombosis and other diseases. In today's society, with the improvement of people's living standards, more and more people are beginning to pay attention to their own health problems. The state of retinal blood vessels is the pathological basis for fundus health and common diseases. If fundus cameras can be widely used in communities, schools and even families, it will have important medical value for early health screening.

[0003] At present, the focusing range of portable fundus cameras is mainly ±10D, and the field of view angle is mainly 30°-40°. There are problems such as small focusing range, small field of view, and high cost. Moreover, due to the limitation of field of view, most of the retinal objective lenses are aspherical. In addition, due to the need to meet the requirements of portability and high resolution, the system volume is limited, which makes it difficult to take both the field of view range and the focusing range into consideration during the design process. For example, the focusing range of the fundus camera in the reference "Optical Design of a New Portable Fundus Camera" reaches ±15D, but its field of view angle is only 40°[1]. The field of view angle of the fundus camera provided in "Research and Development Design of Fundus Camera Optical Device System Based on Mobile Device" reaches 50°, but its focusing range is only ±10D[2]. The field of view angle of a new type of non-mydriatic portable fundus camera reaches 60°, but its focusing range is only -8D to +10D[3].

[0004] References:

[0005] [1] Hong Yang. Optical design of a new portable fundus camera[D]. Jiangsu: Soochow University, 2021.

[0006] [2] Dong Ruya, Hong Chaoyang, Zheng Qingqing, et al. Research and development of fundus camera optical device system based on mobile device[J]. Chinese Medical Equipment, 2022(007):019.

[0007] [3] Liu Yue, Yang Qiang, Wang Qingfeng, et al. A new type of portable fundus camera without mydriasis. 2012[2024-10-16].

[0008] It is still difficult for existing fundus cameras to meet the requirements of fundus screening on a large scale and cover remote areas for screening activities. Therefore, it is particularly important to design a portable fundus camera with a large field of view, simple structure, large focusing range, low cost and high resolution. Summary of the invention

[0009] In view of the deficiencies in the above-mentioned prior art, the present invention designs an optical imaging system based on the Gullstrand-Le Grand100 eye model, and provides an optical imaging system that can achieve a large field of view and meet the needs of short-distance and large-range focusing.

[0010] The specific technical scheme of the present invention is as follows:

[0011] A portable large-field fundus camera optical system comprises a retina objective lens, a focusing lens group and an imaging lens group which are arranged on the same optical axis in sequence from left to right;

[0012] The retina objective lens comprises a first lens, a second lens, a third lens and a fourth lens arranged in sequence from left to right; the first lens is a meniscus lens, the second lens is a biconvex lens, and the third lens and the fourth lens are combined into a double cemented lens;

[0013] The focusing lens group includes a fifth lens, and the fifth lens is a plano-concave lens;

[0014] The imaging lens group includes a front imaging lens group and a rear imaging lens group which are arranged in sequence from left to right; the front imaging lens group includes a sixth lens, a seventh lens, and an eighth lens which are arranged in sequence from left to right, the sixth lens is a plano-convex lens, and the seventh lens and the eighth lens form a double cemented lens; the rear imaging lens group includes a ninth lens, a tenth lens, an eleventh lens, and a twelfth lens which are arranged in sequence from left to right, the ninth lens and the tenth lens form a double cemented lens, the eleventh lens is a meniscus lens, and the twelfth lens is a positive lens.

[0015] Preferably, from left to right, the first lens has a first lens surface and a second lens surface in sequence; the second lens has a third lens surface and a fourth lens surface; the third lens and the fourth lens have a fifth lens surface, a sixth lens surface and a seventh lens surface, the first lens surface is convex to the right, and the curvature radius thereof is in the range of [122.31 mm, 123.31 mm]; the second lens surface is convex to the right, and the curvature radius thereof is in the range of [41.9 mm, 42.9 mm]; the third lens surface is convex to the left, and the curvature radius thereof is in the range of The fourth lens surface is convex to the right, and its curvature radius range is [68.53mm, 69.53mm]; the fifth lens surface is convex to the left, and its curvature radius range is [57.55mm, 58.55mm]; the sixth lens surface is convex to the right, and its curvature radius range is [54.83mm, 55.83mm]; the seventh lens surface is convex to the right, and its curvature radius range is [520.24mm, 521.24mm].

[0016] Preferably, the thickness range of the first lens is [10.25mm, 11.25mm], the thickness range of the second lens is [10.61mm, 11.61mm], the thickness range of the third lens is [14.76mm, 15.76mm], and the thickness range of the fourth lens is [4.43mm, 5.43mm].

[0017] Preferably, the glass material of the first lens is H-LAK3; the glass material of the second lens is H-ZPK5; the glass material of the third lens is H-ZPK5; and the glass material of the fourth lens is H-ZF62GT.

[0018] Preferably, the fifth lens has an eighth lens surface and a ninth lens surface in sequence; the eighth lens surface is a plane; the ninth lens surface is convex toward the left, and its curvature radius ranges from [18.46 mm, 19.46 mm].

[0019] Preferably, the fifth lens has a thickness in the range of [2.15 mm, 3.15 mm].

[0020] Preferably, the glass material of the fifth lens is H-LAK2A.

[0021] Preferably, from left to right, the sixth lens has a tenth lens surface and an eleventh lens surface in sequence, the seventh lens and the eighth lens have a twelfth lens surface, a thirteenth lens surface, and a fourteenth lens surface in sequence, the ninth lens and the tenth lens have a fifteenth lens surface, a sixteenth lens surface, and a seventeenth lens surface in sequence, the eleventh lens has an eighteenth lens surface and a nineteenth lens surface in sequence, and the twelfth lens has a twentieth lens surface and a twenty-first lens surface in sequence; the tenth lens surface is convex to the left, and its curvature radius ranges from [22.19mm, 23.19mm]; the eleventh lens surface is a plane; the twelfth lens surface is convex to the left, and its curvature radius ranges from [9.52mm, 10.52mm]; the thirteenth lens surface is convex to the right, and its curvature radius ranges from [8.25mm, 9.25mm]; the fourteenth lens surface is convex to the left, and its curvature The radius range is [21.32mm, 22.32mm]; the fifteenth lens surface is convex to the right, and the curvature radius range is [10.25mm, 11.25mm]; the sixteenth lens surface is convex to the left, and the curvature radius range is [4.34mm, 5.34mm]; the seventeenth lens surface is convex to the right, and the curvature radius range is [6.75mm, 7.75mm]; the eighteenth lens surface is convex to the right, and the curvature radius range is [5.26mm, 6.26mm]; the nineteenth lens surface is convex to the right, and the curvature radius range is [22.81mm, 23.81mm]; the twentieth lens surface is convex to the left, and the curvature radius range is [15.13mm, 16.13mm]; the twenty-first lens surface is convex to the left, and the curvature radius range is [93.17mm, 94.17mm].

[0022] Preferably, the thickness range of the sixth lens is [9.11mm, 10.11mm], the thickness range of the seventh lens is [7.8mm, 8.8mm], the thickness range of the eighth lens is [1.1mm, 2.1mm], the thickness range of the ninth lens is [3.16mm, 4.16mm], the thickness range of the tenth lens is [2.23mm, 3.23mm], the thickness range of the eleventh lens is [1.9mm, 2.9mm], and the thickness range of the twelfth lens is [7.62mm, 8.62mm].

[0023] Preferably, the glass material of the sixth lens is H-ZLAF50E; the glass material of the seventh lens is H-ZPK5; the glass material of the eighth lens is H-K3; the glass material of the ninth lens is H-F1; the glass material of the tenth lens is H-ZPK7; the glass material of the eleventh lens is H-ZF12; and the glass material of the twelfth lens is H-ZLAF75A.

[0024] The beneficial effects of the present invention are:

[0025] The present invention designs a fundus forming optical imaging system based on the Gullstrand-Le Grand100 eye model, which can achieve a large field of view and meet the requirements of short-distance and large-range focusing optical imaging, and has the following advantages:

[0026] 1. The secondary imaging method is adopted, using a four-piece retina objective lens to form an image in the center, and then the secondary imaging is achieved through the imaging lens group, which reduces the distortion caused by the large field of view and does not require the use of aspherical surfaces.

[0027] 2. Combine the four-piece retina objective lens with the optimized Gaussian lens group to achieve a large field of view and high resolution imaging system.

[0028] 3. Plano-concave lenses are used to eliminate aberrations and serve as the system's focusing lens group to meet the needs of focusing over a large range and a small distance.

[0029] 4. The optical design of the instrument is simple and the manufacturing cost is low. Compared with portable fundus cameras on the market, this design has fewer lenses and can meet the requirements of large field of view and wide range of focusing without using aspherical lenses. The fundus camera optical system of the present invention has a large field of view, a field of view angle of up to 53.13°, a simple system structure, and a system length of less than 190 mm, which meets the requirements of portability. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is a schematic diagram of the optical system structure of the portable large-field-of-view fundus camera of the present invention;

[0031] Figure 2 It is a schematic diagram of imaging of the portable large-field-of-view fundus camera of the present invention. DETAILED DESCRIPTION

[0032] The present invention is further described below with reference to specific examples, but the examples do not limit the present invention in any form.

[0033] refer to Figure 1 The portable large-field fundus camera optical system of the present invention is designed based on the Gullstrand-Le Grand eye model to design an optical imaging system, including a retinal objective lens, a focusing lens group, and an imaging lens group. The retinal objective lens, the focusing lens group, and the imaging lens group are arranged in sequence from left to right on the same optical axis.

[0034] The retina objective lens 200 comprises a first lens 210, a second lens 220, a third lens 230 and a fourth lens 240 arranged from left to right in sequence; the first lens 210 is a meniscus lens, the second lens 220 is a biconvex lens, and the third lens 230 and the fourth lens 240 are combined into a double cemented lens.

[0035] The focusing lens assembly 300 includes a fifth lens 310 , which is a plano-concave lens.

[0036] The imaging lens group 400 includes a front imaging lens group and a rear imaging lens group; the front imaging lens group includes a sixth lens 420, a seventh lens 430, and an eighth lens 440, the sixth lens 420 is a plano-convex lens, the seventh lens 430 and the eighth lens 440 form a double cemented lens; the rear imaging lens group includes a ninth lens 450, a tenth lens 460, an eleventh lens 470, and a twelfth lens 480, the ninth lens 450 and the tenth lens 460 form a double cemented lens, the eleventh lens 470 is a meniscus lens, and the twelfth lens 480 is a positive lens.

[0037] The system uses a four-piece retina objective lens and an improved Gaussian lens group as an imaging lens group. Using secondary imaging, the retina is first imaged in the center of the system through the retina objective lens, and the central image is finally imaged on the CMOS sensor 500 through the focusing lens group and the imaging lens group, and finally a clear fundus image is obtained. A plano-concave lens is used as the focusing lens in the Gaussian lens group to achieve a wide range of short-distance focusing.

[0038] From left to right, the first lens 210 has a first lens surface 201 and a second lens surface 202 in sequence; the second lens 220 has a third lens surface 203 and a fourth lens surface 204; the third lens 230 and the fourth lens 240 have a fifth lens surface 205, a sixth lens surface 206 and a seventh lens surface 207, and the fifth lens 310 has an eighth lens surface 301 and a ninth lens surface 302 in sequence; the sixth lens 420 has a tenth lens surface 401 and an eleventh lens surface 402 in sequence, the seventh lens 430 and the eighth lens 440 have a twelfth lens surface 403, a thirteenth lens surface 404 and a fourteenth lens surface 405 in sequence, the ninth lens 450 and the tenth lens 460 have a fifteenth lens surface 406, a sixteenth lens surface 407 and a seventeenth lens surface 408 in sequence, the eleventh lens 470 has an eighteenth lens surface 409 and a nineteenth lens surface 410 in sequence, and the twelfth lens 480 has a twentieth lens surface 411 and a twenty-first lens surface 412 in sequence.

[0039] The first lens surface 201 is convex toward the right, and the range of its radius of curvature is [122.31mm, 123.31mm]; the second lens surface 202 is convex toward the right, and the range of its radius of curvature is [41.9mm, 42.9mm]; the third lens surface 203 is convex toward the left, and the range of its radius of curvature is [319.07mm, 320.07mm]; the fourth lens surface 204 is convex toward the right, and the range of its radius of curvature is [68.53mm, 69.53mm]; the fifth lens surface 205 is convex toward the left, and the range of its radius of curvature is [57.55mm, 58.55mm]; the sixth lens surface 206 is convex toward the right, and the range of its radius of curvature is [54.83mm, 55.83mm]; the seventh lens surface 207 is convex toward the right, and the range of its radius of curvature is [520.24mm, 521.24mm].

[0040] The eighth lens surface 301 is a plane; the ninth lens surface 302 is convex toward the left, and its curvature radius ranges from [18.46 mm, 19.46 mm].

[0041] The tenth lens surface 401 is convex toward the left direction, and the range of its curvature radius is [22.19mm, 23.19mm]; the eleventh lens surface 402 is a plane; the twelfth lens surface 403 is convex toward the left direction, and the range of its curvature radius is [9.52mm, 10.52mm]; the thirteenth lens surface 404 is convex toward the right direction, and the range of its curvature radius is [8.25mm, 9.25mm]; the fourteenth lens surface 405 is convex toward the left direction, and the range of its curvature radius is [21.32mm, 22.32mm]; the fifteenth lens surface 406 is convex toward the right direction, and the range of its curvature radius is [10.25mm, 11.25mm]; the sixteenth lens surface 407 is convex toward the left direction The seventeenth lens surface 408 is convex toward the right, and the curvature radius range is [4.34mm, 5.34mm]; the seventeenth lens surface 408 is convex toward the right, and the curvature radius range is [6.75mm, 7.75mm]; the eighteenth lens surface 409 is convex toward the right, and the curvature radius range is [5.26mm, 6.26mm]; the nineteenth lens surface 410 is convex toward the right, and the curvature radius range is [22.81mm, 23.81mm]; the twentieth lens surface 411 is convex toward the left, and the curvature radius range is [15.13mm, 16.13mm]; the twenty-first lens surface 412 is convex toward the left, and the curvature radius range is [93.17mm, 94.17mm].

[0042] The thickness range of the first lens 210 is [10.25mm, 11.25mm], the thickness range of the second lens 220 is [10.61mm, 11.61mm], the thickness range of the third lens 230 is [14.76mm, 15.76mm], the thickness range of the fourth lens 240 is [4.43mm, 5.43mm], and the thickness range of the fifth lens 310 is [2.15mm, 3.15mm]. The thickness range of the sixth lens 420 is [9.11 mm, 10.11 mm], the thickness range of the seventh lens 430 is [7.8 mm, 8.8 mm], the thickness range of the eighth lens 440 is [1.1 mm, 2.1 mm], the thickness range of the ninth lens 450 is [3.16 mm, 4.16 mm], the thickness range of the tenth lens 460 is [2.23 mm, 3.23 mm], the thickness range of the eleventh lens 470 is [1.9 mm, 2.9 mm], and the thickness range of the twelfth lens 480 is [7.62 mm, 8.62 mm].

[0043] The glass material of the first lens 210 is H-LAK3; the glass material of the second lens 220 is H-ZPK5; the glass material of the third lens 230 is H-ZPK5; the glass material of the fourth lens 240 is H-ZF62GT. The glass material of the fifth lens 310 is H-LAK2A. The glass material of the sixth lens 420 is H-ZLAF50E; the glass material of the seventh lens 430 is H-ZPK5; the glass material of the eighth lens 440 is H-K3; the glass material of the ninth lens 450 is H-F1; the glass material of the tenth lens 460 is H-ZPK7; the glass material of the eleventh lens 470 is H-ZF12; and the glass material of the twelfth lens 480 is H-ZLAF75A.

[0044] Example 1

[0045] In a specific embodiment of the present invention, the curvature radius, thickness and material of each lens surface and lens of the portable large-field-of-view fundus camera optical system of the present invention are as shown in Table 1-2.

[0046] Table 1 Curvature radius of each lens surface

[0047]

[0048]

[0049] Note: Here, it is assumed that the lens surface and the principal optical axis produce an intersection. If the center of the sphere where the lens surface is located is on the left side of the intersection, then the curvature radius of the lens surface is negative. Conversely, if the center of the sphere where the lens surface is located is on the right side of the intersection, then the curvature radius of the lens surface is positive.

[0050] Table 2 Lens thickness and material

[0051] lens Thickness / (mm) Glass material First lens 210 11.25 H-LAK3 Second lens 220 11.61 H-ZPK5 The third lens 230 15.76 H-ZPK5 The fourth lens 240 5.43 H-ZF62GT Fifth lens 310 3.15 H-LAK2A Sixth lens 420 10.11 H-ZLAF50E Seventh lens 430 8.8 H-ZPK5 Eighth lens 440 2.1 H-K3 Ninth lens 450 4.16 H-F1 Tenth lens 460 3.23 H-ZPK7 Eleventh lens 470 2.9 H-ZF12 The twelfth lens 480 8.62 H-ZLAF75A

[0052] The optical system of the above embodiment is tested and it is known that when the Nyquist frequency is 145lp / mm, the modulation transfer function MTF of the imaging system is 0.3. At the same time, the distance between the image plane of the optical system and the twenty-first lens surface 412 in this embodiment is 11.6mm; the distance between the image plane of the optical system and the first lens surface 201 in this embodiment is 190mm; the distance between the first lens surface 201 and the human eye model 100 is 38mm. The focusing range of the optical system in this embodiment is ±20D. When the focus is +20D and the Nyquist frequency is 145lp / mm, the modulation transfer function MTF of the imaging system is 0.2; when the focus is -20D and the Nyquist frequency is 145lp / mm, the modulation transfer function MTF of the imaging system is 0.2. In this implementation case, when the focus is +20D, the distance between the eighth lens surface and the seventh lens surface is 11.6mm. When the focus is -20D, the distance between the eighth lens surface and the seventh lens surface is 16.4mm. The total focusing distance is 4.8mm.

[0053] Table 3 Modern optical processing levels

[0054]

[0055] In order to verify the optical system, the above optical system was subjected to 1000 Monte Carlo tests, and the tolerance coefficient of Q6 level of modern optical processing was used for analysis. The MTF-meridian sagittal average of the imaging system modulation transfer function at the Nyquist frequency of 145lp / mm was used as the judgment condition, and the focusing lens was used as the compensator, and a compensation range of ±0.2 was added. When the focusing lens group is located at 0D, the Monte Carlo test has a probability of 98% that the imaging system modulation transfer function MTF is 0.256 when the Nyquist frequency is 145lp / mm; when the focusing lens group is located at +20D, the Monte Carlo test has a probability of 98% that the imaging system modulation transfer function MTF is 0.226 when the Nyquist frequency is 145lp / mm; when the focusing lens group is located at -20D, the Monte Carlo test has a probability greater than 98% that the imaging system modulation transfer function MTF is 0.213 when the Nyquist frequency is 145lp / mm.

[0056] Furthermore, the system is tested by actual processing, such as Figure 2As shown, a target is placed 1m+38mm away from the system, where 38mm is the distance between the theoretical system and the human eye model. Through testing, the image shooting height is 1.02m. Through the calculation of the triangular sine function, it can be obtained that the field of view of the system is 53.13°, which meets the requirements of a large field of view. The length of the system does not exceed 190mm, which meets the requirements of being portable. In addition, the internal focusing range is ±20D, the moving distance of the focusing lens group is 4.8mm, the camera structure is simple, and spherical lenses are used, which is relatively low in cost.

[0057] The technical features of the above-mentioned embodiments can be combined arbitrarily. To make the description concise, all possible combinations of the technical features in the above-mentioned embodiments are not described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification. It should be pointed out that for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be based on the attached claims.

Claims

1. A portable large-field-of-view fundus camera optical system, comprising a retina objective lens, a focusing lens group and an imaging lens group arranged in sequence from left to right on the same optical axis, characterized in that: The retina objective lens (200) comprises a first lens (210), a second lens (220), a third lens (230) and a fourth lens (240) which are arranged in sequence from left to right; the first lens (210) is a meniscus lens, the second lens (220) is a biconvex lens, and the third lens (230) and the fourth lens (240) are combined into a double cemented lens; The focusing lens assembly (300) comprises a fifth lens (310), and the fifth lens (310) is a plano-concave lens; The imaging lens group (400) comprises a front imaging lens group and a rear imaging lens group which are arranged in sequence from left to right. The front imaging lens group comprises a sixth lens (420), a seventh lens (430), and an eighth lens (440) which are arranged in sequence from left to right. The sixth lens (420) is a plano-convex lens. The seventh lens (430) and the eighth lens (440) form a double cemented lens. The rear imaging lens group comprises a ninth lens (450), a tenth lens (460), an eleventh lens (470), and a twelfth lens (480) which are arranged in sequence from left to right. The ninth lens (450) and the tenth lens (460) form a double cemented lens. The eleventh lens (470) is a meniscus lens, and the twelfth lens (480) is a positive lens.

2. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: From left to right, the first lens (210) has a first lens surface (201) and a second lens surface (202) in sequence; the second lens (220) has a third lens surface (203) and a fourth lens surface (204); the third lens (230) and the fourth lens (240) have a fifth lens surface (205), a sixth lens surface (206) and a seventh lens surface (207), The first lens surface (201) is convex toward the right, and its curvature radius ranges from [122.31mm, 123.31mm]; the second lens surface (202) is convex toward the right, and its curvature radius ranges from [41.9mm, 42.9mm]; the third lens surface (203) is convex toward the left, and its curvature radius ranges from [319.07mm, 320.07mm]; the fourth lens surface (204) is convex toward the right, and its curvature radius ranges from [ The radius range is [68.53mm, 69.53mm]; the fifth lens surface (205) is convex toward the left, and its curvature radius range is [57.55mm, 58.55mm]; the sixth lens surface (206) is convex toward the right, and its curvature radius range is [54.83mm, 55.83mm]; the seventh lens surface (207) is convex toward the right, and its curvature radius range is [520.24mm, 521.24mm].

3. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The thickness range of the first lens (210) is [10.25 mm, 11.25 mm], the thickness range of the second lens (220) is [10.61 mm, 11.61 mm], the thickness range of the third lens (230) is [14.76 mm, 15.76 mm], and the thickness range of the fourth lens (240) is [4.43 mm, 5.43 mm].

4. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The glass material of the first lens (210) is H-LAK3; the glass material of the second lens (220) is H-ZPK5; the glass material of the third lens (230) is H-ZPK5; and the glass material of the fourth lens (240) is H-ZF62GT.

5. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The fifth lens (310) has an eighth lens surface (301) and a ninth lens surface (302) in sequence; the eighth lens surface (301) is a plane; the ninth lens surface (302) is convex toward the left, and its curvature radius ranges from [18.46 mm, 19.46 mm].

6. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The thickness of the fifth lens (310) is in the range of [2.15 mm, 3.15 mm].

7. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The glass material of the fifth lens (310) is H-LAK2A.

8. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: From left to right, the sixth lens (420) has a tenth lens surface (401) and an eleventh lens surface (402) in sequence, the seventh lens (430) and the eighth lens (440) have a twelfth lens surface (403), a thirteenth lens surface (404), and a fourteenth lens surface (405) in sequence, the ninth lens (450) and the tenth lens (460) have a fifteenth lens surface (406), a sixteenth lens surface (407), and a seventeenth lens surface (408) in sequence, the eleventh lens (470) has an eighteenth lens surface (409) and a nineteenth lens surface (410) in sequence, and the twelfth lens (480) has a twentieth lens surface (411) and a twenty-first lens surface (412) in sequence; The tenth lens surface (401) is convex toward the left, and its curvature radius ranges from [22.19mm, 23.19mm]; the eleventh lens surface (402) is a plane; the twelfth lens surface (403) is convex toward the left, and its curvature radius ranges from [9.52mm, 10.52mm]; the thirteenth lens surface (404) is convex toward the right, and its curvature radius ranges from [8.25mm, 9.25mm]; the fourteenth lens surface (405) is convex toward the left, and its curvature radius ranges from [21.32mm, 22.32mm]; the fifteenth lens surface (406) is convex toward the right, and its curvature radius ranges from [10.25mm, 11.25mm]; the sixteenth lens surface (407) is convex toward the right The seventeenth lens surface (408) is convex toward the right, and its radius of curvature is in the range of [4.34mm, 5.34mm]; the seventeenth lens surface (408) is convex toward the right, and its radius of curvature is in the range of [6.75mm, 7.75mm]; the eighteenth lens surface (409) is convex toward the right, and its radius of curvature is in the range of [5.26mm, 6.26mm]; the nineteenth lens surface (410) is convex toward the right, and its radius of curvature is in the range of [22.81mm, 23.81mm]; the twentieth lens surface (411) is convex toward the left, and its radius of curvature is in the range of [15.13mm, 16.13mm]; the twenty-first (412) lens surface is convex toward the left, and its radius of curvature is in the range of [93.17mm, 94.17mm].

9. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The thickness range of the sixth lens (420) is [9.11 mm, 10.11 mm], the thickness range of the seventh lens (430) is [7.8 mm, 8.8 mm], the thickness range of the eighth lens 440 is [1.1 mm, 2.1 mm], the thickness range of the ninth lens (450) is [3.16 mm, 4.16 mm], the thickness range of the tenth lens (460) is [2.23 mm, 3.23 mm], the thickness range of the eleventh lens (470) is [1.9 mm, 2.9 mm], and the thickness range of the twelfth lens (480) is [7.62 mm, 8.62 mm].

10. The portable large-field-of-view fundus camera optical system according to claim 1, characterized in that: The glass material of the sixth lens (420) is H-ZLAF50E; the glass material of the seventh lens (430) is H-ZPK5; the glass material of the eighth lens (440) is H-K3; the glass material of the ninth lens (450) is H-F1; the glass material of the tenth lens (460) is H-ZPK7; the glass material of the eleventh lens (470) is H-ZF12; and the glass material of the twelfth lens (480) is H-ZLAF75A.

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