Paeonia suffruticosa compatible capsule for preventing and treating encephalatrophy and preparation method thereof

Abstract

The invention provides a peony compatible capsule for preventing and treating encephalatrophy and a preparation method thereof, and relates to the field of traditional Chinese medicinal materials. Comprising a capsule wall material and an effective component core material, and the core material comprises the following raw materials in parts by weight: 30-50 parts of peony oil, 20-30 parts of black sesame oil, 10-20 parts of walnut oil, 0.01-0.05 part of a selenium source, 1-5 parts of peanut oil, 1-5 parts of fructus alpiniae oxyphyllae oil and 1-5 parts of ginkgo oil. The tea has the effects of reducing blood fat and blood pressure, enhancing autoimmunity, relieving climacteric syndrome, refreshing and strengthening brain, enhancing attention and memory, relieving neurasthenia and insomnia, eliminating brain fatigue, improving cerebrovascular functions, preventing and treating encephalatrophy and the like.

Description

Technical Field

[0001] The invention relates to the field of Chinese patent medicines, and in particular to a peony-combination capsule for preventing and treating cerebral atrophy and a preparation method thereof. Background Art

[0002] Brain atrophy is the phenomenon of atrophy caused by organic lesions in the brain tissue itself, which is manifested by a reduction in brain tissue volume, a decrease in the number of cells, and an expansion of the ventricles and subarachnoid space. This phenomenon can be caused by a variety of causes, including but not limited to heredity, brain trauma, stroke, encephalitis, meningitis, cerebrovascular malformations, brain tumors, long-term epileptic seizures, excessive smoking and drinking, malnutrition, thyroid dysfunction, gas poisoning, alcohol poisoning, cerebral arteriosclerosis, cerebral ischemia, hypoxia, etc.

[0003] Symptoms of brain atrophy usually include memory loss, inattention, personality changes, language disorders, and decreased motor coordination. There are various treatments for brain atrophy, but there is no complete cure. In terms of drug treatment, for patients with decreased cognitive function, cholinesterase inhibitors can be used to increase the concentration of acetylcholine in the brain and improve memory and cognitive function. Drugs that improve microcirculation and promote brain metabolism can also be used to relieve symptoms and delay disease progression. For patients with psychiatric symptoms such as depression and anxiety, antidepressants or anti-anxiety drugs can be added. Rehabilitation exercises are also an important means of treating brain atrophy. Through rehabilitation training of cognitive function, language function, and limb movement function, patients' daily living ability, social ability, and activity ability can be improved. Training includes regular aerobic exercises such as playing mahjong, brisk walking, jogging, and targeted brain training such as memory games and puzzles, which can help slow the progression of brain atrophy.

[0004] Compared with active treatment after the onset of symptoms of brain atrophy, it is also crucial to prevent brain atrophy in daily life. For example, lifestyle intervention, dietary adjustment, cognitive training, participation in social activities, and regular physical examinations. Establishing healthy living habits, such as quitting smoking, limiting alcohol intake, eating a balanced diet, and exercising regularly, can help reduce the risk of brain atrophy. A reasonable diet structure helps provide the nutrients needed by the brain and supports its normal function, thereby playing a certain preventive role. Cognitive training can improve the function and flexibility of the brain and enhance memory and thinking ability. Active participation in social activities can stimulate the connection between brain neurons and promote information exchange and sharing. Regular physical examinations can detect potential brain health problems early, making it easier to take timely intervention measures.

[0005] Currently, drugs used to treat and prevent cerebral atrophy have low cure rates and poor preventive effects. Summary of the invention

[0006] The object of the present invention is to provide a peony compatibility capsule for preventing and treating cerebral atrophy, which has the effects of lowering blood lipids and blood pressure, enhancing autoimmunity, alleviating menopausal syndrome, refreshing the mind and strengthening the brain, enhancing attention and memory, relieving neurasthenia and insomnia, eliminating brain fatigue, improving cerebrovascular function, preventing and treating cerebral atrophy and the like.

[0007] Another object of the present invention is to provide a method for preparing peony-combination capsules for preventing and treating cerebral atrophy, wherein the preparation method is simple and efficient.

[0008] The present invention solves the technical problem by adopting the following technical solutions.

[0009] On the one hand, an embodiment of the present invention provides a peony-combination capsule for preventing and treating cerebral atrophy, comprising a capsule wall material and an effective ingredient core material, wherein the core material comprises the following raw materials by weight:

[0010] 30-50 parts of peony oil, 20-30 parts of black sesame oil, 10-20 parts of walnut oil, 0.01-0.05 parts of selenium source, 1-5 parts of peanut oil, 1-5 parts of Alpinia oxyphylla oil, and 1-5 parts of ginkgo oil.

[0011] In some embodiments of the present invention, the core material further comprises, by weight:

[0012] 5-10 parts of Gastrodia elata extract, 1-5 parts of Astragalus powder, and 1-5 parts of Angelica sinensis powder.

[0013] In some embodiments of the present invention, the core material comprises the following raw materials by weight:

[0014] 50 parts of peony oil, 30 parts of black sesame oil, 20 parts of walnut oil, 0.05 parts of selenium source, 5 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 5 parts of ginkgo oil, 10 parts of Gastrodia elata extract, 5 parts of astragalus powder, and 5 parts of angelica powder.

[0015] In some embodiments of the present invention, the core material comprises the following raw materials by weight:

[0016] 30 parts of peony oil, 20 parts of black sesame oil, 10 parts of walnut oil, 0.01 parts of selenium source, 1 part of peanut oil, 1 part of Alpinia oxyphylla oil, 1 part of ginkgo oil, 5 parts of Gastrodia elata extract, 1 part of astragalus powder, and 1 part of angelica powder.

[0017] In some embodiments of the present invention, the core material comprises the following raw materials by weight:

[0018] 40 parts of peony oil, 25 parts of black sesame oil, 15 parts of walnut oil, 0.05 parts of selenium source, 3 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 1 part of ginkgo oil, 8 parts of Gastrodia elata extract, 5 parts of astragalus powder, and 5 parts of angelica powder.

[0019] The functions of the raw materials in the core material of the present invention are as follows:

[0020] Peony oil, namely peony seed oil: rich in biologically active ingredients such as peony phenol, peony saponin, peony polysaccharide and unsaturated fatty acids. Its effects are as follows: Antioxidant: Peony seed oil has a very significant antioxidant effect, and its ability to scavenge free radicals far exceeds that of other oils. Lowering blood lipids: The content of unsaturated fatty acids is as high as 92%, and the content of α-linolenic acid is rich, which can effectively reduce cholesterol and triglycerides in the blood, thereby helping to regulate blood lipid levels. Lowering blood sugar: Its active ingredients can stimulate the secretion of insulin, improve the utilization rate of blood sugar, and help lower blood sugar levels. Contribute to brain development: It provides comprehensive nutritional support for the brain, and has a significant impact on the division, proliferation, nerve conduction, and growth and development of synapses of brain cells.

[0021] Black sesame oil: rich in vitamin E, sesamoid compounds, linolenic acid, etc. The effects are as follows: Antioxidant: rich in vitamin E and other antioxidants, it can remove free radicals and slow down the process of cell oxidation and aging. Intestinal moisturizing and laxative: unsaturated fatty acids help promote intestinal peristalsis and improve constipation. Nourishing the liver and kidneys: can be used to treat symptoms caused by liver and kidney deficiency.

[0022] Walnut oil: The main components are fatty acids, including linoleic acid, linolenic acid, oleic acid, etc. The effects are as follows: Brain health: Fatty acids play an important role in brain development and the nervous system, and can improve memory and learning ability. Protect the liver: The linoleic acid contained in it can promote the metabolism and excretion of liver fat, help improve fatty liver, protect the liver, and prevent the occurrence of liver diseases. Protect eyesight: Vitamin A and Omega-3 fatty acids are good for eye health and can prevent age-related macular degeneration and other eye diseases.

[0023] Peanut oil: contains glycerides of various fatty acids, with unsaturated fatty acid content of more than 80%. It also contains saturated fatty acids such as palmitic acid, stearic acid and arachidic acid, as well as mineral elements such as vitamin E, calcium, potassium, iron, magnesium, and selenium. The effects are as follows: lowering cholesterol: it can decompose cholesterol in the human body into bile acid and excrete it from the body, thereby reducing the cholesterol content in plasma. Lubricating intestines: it can be used by people with constipation to relieve constipation symptoms. Delaying aging: vitamin E has obvious antioxidant and anti-aging functions, and is also beneficial in preventing cardiovascular and cerebrovascular diseases and preventing and treating atherosclerosis.

[0024] Alpinia oxyphylla oil: includes fatty acids, vitamin E, folic acid, choline, amino acids, flavonoids, polyphenols, etc. The effects are as follows: Antioxidant: It can inhibit lipid peroxidation, reduce cell oxidative damage, and protect cell membrane structure and function. Anti-inflammatory: Alpinia oxyphylla oil can inhibit the production of inflammatory factors (such as TNF-α, IL-6, IL-1β) and reduce inflammatory response. Hypolipidemic: Rich in unsaturated fatty acids, especially linoleic acid and α-linolenic acid, it can reduce triglyceride levels, increase high-density lipoprotein cholesterol levels, improve blood lipid profiles, and reduce the risk of cardiovascular disease. Hypoglycemic: Choline can improve insulin sensitivity, promote glucose utilization, and lower blood sugar levels; folic acid participates in the synthesis of nucleic acids and proteins, and plays an important role in the synthesis and secretion of insulin. Antibacterial: It can inhibit the growth of a variety of bacteria (such as Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae, etc.), and has an inhibitory effect on fungi. Neuroprotective: It can improve nerve function and prevent the occurrence of neurodegenerative diseases. Anti-tumor: It can inhibit the growth and proliferation of cancer cells, induce apoptosis of cancer cells, and reduce tumor growth.

[0025] Ginkgo oil: contains 83% unsaturated fatty acids, the main nutrients are octadecadienoic acid and octadecenoic acid, and also contains ginkgolic acid, ginkgo phenol, pentose polysaccharide, liposterol, riboflavin, carotene, calcium, phosphorus, iron, potassium, magnesium and other trace elements. The effects are as follows: regulating blood lipids and lowering cholesterol: octadecadienoic acid has a strong blood lipid regulating effect, can promote the decomposition of cholesterol, soften blood vessels, and fat-soluble components also have the effect of lowering cholesterol. Prevent cardiovascular and cerebrovascular diseases: antiplatelet activating factor can promote blood circulation, and flavonoids can prevent arteriosclerosis. Enhance memory and protect vision: It can be used as a carrier of fat-soluble vitamins to promote the absorption of vitamin E, vitamin A, vitamin D and vitamin K. It can also participate in the formation of phospholipid molecules, thereby affecting the activity of biological membranes, increasing brain capacity, improving vision, etc.; carotene also has an excellent effect on protecting vision. Resist radiation and enhance immunity: octadecadienoic acid can promote protein synthesis and metabolism, promote tissue regeneration, and help resist radiation. Liver protection and detoxification: Rich vitamins and high-quality water-soluble proteins can assist the absorption of vitamins A / D / E / F / K and calcium, and play a role in liver protection and detoxification; rich trace elements can also repair the liver and promote liver tissue regeneration. Inhibit and kill tumor cells: Contains hydroxyphenols and hydroxyphenolic acid compounds, etc., which can inhibit bacteria and kill insects; linoleic acid has an inhibitory and toxic effect on cancer cell cultures. Skin care: Contains rich vitamin E, riboflavin, carotene, etc., has an antioxidant effect, can delay cell aging, and prevent skin roughness.

[0026] Gastrodia extract: contains gastrodin, gastrodin aglycone, gastrodioside, parishin, vanillin, β2-sterol, p-hydroxybenzaldehyde, citric acid, succinic acid, etc. It has the following effects: calming the liver, relieving wind and stopping spasms, and is used for headache, dizziness, numbness of limbs, infantile convulsions, epilepsy, convulsions, and tetanus.

[0027] Astragalus powder: contains saponins, flavonoids (mainly formononetin and calycosin isoflavones), amino acids, betaine, etc. It has the following effects: replenishing qi and raising yang, consolidating the exterior and stopping sweating, promoting diuresis and reducing swelling, promoting fluid and nourishing blood, promoting stagnation and relieving arthralgia, expelling toxins and expelling pus, and healing sores and promoting muscle regeneration. It is used to treat qi deficiency and fatigue, poor appetite and loose stools, sinking of qi in the middle, chronic diarrhea and prolapse of the anus, bloody stool and metrorrhagia, spontaneous sweating due to exterior deficiency, edema due to qi deficiency, internal heat and thirst, sallow complexion due to blood deficiency, hemiplegia, pain and numbness, carbuncle and carbuncle that are difficult to ulcerate, and carbuncle that does not heal for a long time. It regulates immune function, resists fatigue, resists stress, promotes hematopoiesis, delays aging, regulates gastrointestinal motility, resists liver damage, regulates blood sugar, and regulates blood lipids. It is anti-viral, anti-cancer, and anti-myocardial ischemia, can enhance learning and memory functions, has a protective effect on nephrotic syndrome, acute ischemia-reperfusion renal injury, and diabetic nephropathy, can improve myocardial contraction and relaxation functions, and improves hypoxia tolerance.

[0028] Angelica powder: contains n-butenoyl lactone, ferulic acid, niacin, sucrose and various amino acids. Its effects are as follows: nourishing blood, regulating menstruation and relieving pain, moisturizing and lubricating the intestines. Promoting hematopoiesis: significantly increasing the content of red blood cells, white blood cells and hemoglobin. Inhibiting platelet aggregation: anti-thrombotic, regulating blood lipids. Anti-myocardial ischemia, anti-arrhythmia: dilate blood vessels, lower blood pressure. Regulate uterine smooth muscle. Enhance immunity, anti-inflammatory, anti-oxidation, scavenging free radicals.

[0029] The peony compatibility capsule of the present invention contains multiple unsaturated fatty acids, which can relieve menopausal syndrome, refresh the mind and strengthen the brain, enhance attention and memory, relieve neurasthenia and insomnia, eliminate brain fatigue, and further achieve the therapeutic effect of preventing brain atrophy.

[0030] In some embodiments of the present invention, the particle size of the astragalus powder is 10-50 um, and the particle size of the angelica powder is 10-50 um.

[0031] In some embodiments of the present invention, the Gastrodia elata extract is prepared by the following method:

[0032] The dried Gastrodia elata slices are soaked in water or 10% ethanol aqueous solution for 30-60 minutes and ultrasonically shaken at the same time; then repeatedly freeze-thawed at -10-0°C; reflux extraction is performed, the extract is collected, concentrated and dried into powder, and the Gastrodia elata extract is obtained.

[0033] On the other hand, the present invention provides a method for preparing a peony-combination capsule for preventing and treating cerebral atrophy, comprising the following steps: mixing the raw materials of the core material evenly and filling the mixture into the capsule wall material.

[0034] Compared with the prior art, the embodiments of the present invention have at least the following advantages or beneficial effects:

[0035] The peony compatibility capsule provided by the invention has peony oil, black sesame oil and walnut oil as main ingredients, is rich in nutrition, and has an unsaturated fatty acid content of more than 92%, wherein the unsaturated fatty acid a-linolenic acid is the main element for synthesizing cell membranes, and is an indispensable unsaturated fatty acid that cannot be synthesized or replaced by the human body. The capsule of the invention not only contains rich DHA, linolenic acid and linoleic acid, but also contains unique nutrients such as paeonol, peony saponin, peony polysaccharide, fuccosterol, squalene and the like. The composition has the effects of lowering blood lipids and blood pressure, enhancing autoimmunity, treating diabetes, preventing and treating cancer, losing weight, preventing and treating cerebral stroke and myocardial infarction, clearing harmful substances in the blood and preventing and treating heart disease, relieving menopausal syndrome, refreshing the mind and strengthening the brain, enhancing attention and memory, relieving neurasthenia and insomnia, eliminating brain fatigue, improving cerebrovascular function, preventing and treating brain atrophy, assisting in the treatment of multiple sclerosis, assisting in the treatment of rheumatoid arthritis, being used for skin ringworm or eczema, preventing and treating constipation, diarrhea and gastrointestinal syndrome, preventing anemia, activating brain cells, eliminating blood vessel cholesterol, nourishing blood and replenishing qi, and the like. DETAILED DESCRIPTION

[0036] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to conventional conditions or conditions recommended by the manufacturer. If the manufacturer of the reagents or instruments used is not specified, they are all conventional products that can be purchased commercially.

[0037] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments may be combined with each other. The present invention will be described in detail below with reference to specific embodiments.

[0038] The features and performance of the present invention are further described in detail below in conjunction with the embodiments.

[0039] Example 1

[0040] The capsules of this embodiment were prepared according to the following ratio:

[0041] 50 parts of peony oil, 30 parts of black sesame oil, 20 parts of walnut oil, 0.05 parts of selenium source (selenized carrageenan), 5 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 5 parts of ginkgo oil, 10 parts of Gastrodia elata extract, 5 parts of astragalus powder, and 5 parts of angelica powder.

[0042] The Gastrodia elata extract is prepared as follows: the dried Gastrodia elata slices are soaked in a 10% ethanol aqueous solution by volume for 60 minutes, and the Gastrodia elata slices are ultrasonically vibrated at a frequency of 80KHz; then the slices are repeatedly frozen and thawed at -10°C for 3 times; the Gastrodia elata slices and the soaked ethanol aqueous solution are refluxed at 90°C, the extract is collected, concentrated and dried into powder, and the Gastrodia elata extract is obtained.

[0043] The astragalus powder is prepared as follows: the dried astragalus is sliced, crushed into fine powder, and sieved, wherein the average particle size of the astragalus powder is 45um.

[0044] The angelica powder is prepared as follows: the dried angelica is sliced, crushed into fine powder, and sieved, wherein the average particle size of the astragalus powder is 30 um.

[0045] After the above raw materials are mixed evenly, they are filled into the capsule wall material, wherein the weight of the core material in each capsule is 2.5 g.

[0046] Example 2

[0047] The capsules of this embodiment were prepared according to the following ratio:

[0048] 30 parts of peony oil, 20 parts of black sesame oil, 10 parts of walnut oil, 0.01 parts of selenium source, 1 part of peanut oil, 1 part of Alpinia oxyphylla oil, 1 part of ginkgo oil, 5 parts of Gastrodia elata extract, 1 part of astragalus powder, and 1 part of angelica powder.

[0049] The core material of this embodiment is the same as that of embodiment 1, and the preparation method is also the same.

[0050] Example 3

[0051] The capsules of this embodiment were prepared according to the following ratio:

[0052] 40 parts of peony oil, 25 parts of black sesame oil, 15 parts of walnut oil, 0.05 parts of selenium source, 3 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 1 part of ginkgo oil, 8 parts of Gastrodia elata extract, 5 parts of astragalus powder, and 5 parts of angelica powder.

[0053] The core material of this embodiment is the same as that of embodiment 1, and the preparation method is also the same.

[0054] Example 4

[0055] The capsules of this embodiment were prepared according to the following ratio:

[0056] 35 parts of peony oil, 20 parts of black sesame oil, 10 parts of walnut oil, 0.05 parts of selenium source (selenized carrageenan), 5 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 5 parts of ginkgo oil, 5 parts of Gastrodia elata extract, 1 part of astragalus powder, and 5 parts of angelica powder.

[0057] The Gastrodia elata extract is prepared as follows: the dried Gastrodia elata slices are soaked in a 10% ethanol aqueous solution by volume for 30 minutes, and the Gastrodia elata slices are ultrasonically vibrated at a frequency of 60KHz; then the slices are repeatedly frozen and thawed at -10°C for 5 times; the Gastrodia elata slices and the soaked ethanol aqueous solution are refluxed and extracted at 80°C, the extract is collected, concentrated and dried into powder, and the Gastrodia elata extract is obtained.

[0058] The astragalus powder is prepared as follows: the dried astragalus is sliced, crushed into fine powder, and sieved, wherein the average particle size of the astragalus powder is 10 um.

[0059] The angelica powder is prepared as follows: the dried angelica is sliced, crushed into fine powder, and sieved, wherein the average particle size of the astragalus powder is 10 um.

[0060] After the above raw materials are mixed evenly, they are filled into the capsule wall material, wherein the weight of the core material in each capsule is 2.5 g.

[0061] Example 5

[0062] The capsules of this embodiment were prepared according to the following ratio:

[0063] 50 parts of peony oil, 30 parts of black sesame oil, 20 parts of walnut oil, 0.01 parts of selenium source (selenized carrageenan), 1 part of peanut oil, 5 parts of Alpinia oxyphylla oil, 1 part of ginkgo oil, 5 parts of Gastrodia elata extract, 1 part of astragalus powder, and 5 parts of angelica powder.

[0064] The Gastrodia elata extract is prepared as follows: the dried Gastrodia elata slices are soaked in a 10% ethanol aqueous solution by volume for 40 minutes, and the Gastrodia elata slices are ultrasonically vibrated at a frequency of 80KHz; then the slices are repeatedly frozen and thawed at -10°C for 3 times; the Gastrodia elata slices and the soaked ethanol aqueous solution are refluxed and extracted at 80°C, the extract is collected, concentrated and dried into powder, and the Gastrodia elata extract is obtained.

[0065] The astragalus powder is prepared as follows: the dried astragalus is sliced, crushed into fine powder, and sieved, wherein the average particle size of the astragalus powder is 50um.

[0066] The angelica powder is prepared as follows: the dried angelica is sliced, crushed into fine powder, and sieved, wherein the average particle size of the astragalus powder is 50 um.

[0067] After the above raw materials are mixed evenly, they are filled into the capsule wall material, wherein the weight of the core material in each capsule is 2.5 g.

[0068] Typical Cases

[0069] Case 1: Li, female, 62 years old. She was diagnosed with cerebral atrophy in July 2022. She began to complain of dizziness and dizziness in February. In the past month, she has been forgetful and insomnia, occasionally unstable, confused, sluggish, and did not know the way home after leaving home. Her appetite was OK, her response to questions was slow, her tongue coating was thin and white, and her pulse was weak. Chinese medicine diagnosed her as forgetfulness due to insufficient kidney essence and deficiency of qi and blood. Western medicine diagnosed her as cerebral atrophy. According to Chinese medicine diagnosis, she needs to be treated with kidney tonification, qi invigoration, blood circulation, brain invigoration, phlegm removal, and revelation. Take the capsules of Example 1, 2 capsules each time, once in the morning and evening, after meals, avoid eating raw and cold food, and eat a low-salt, low-fat diet, strengthen physical exercise, keep the patient in a good mood, and guide the patient to do more language function exercises; after taking the medicine for 3 months, the patient's symptoms were alleviated, with only mild amnesia symptoms. After continuing to take the medicine for 3 months, the amnesia symptoms disappeared, and the patient was able to live independently and normally.

[0070] Case 2: Jiang, male, 65 years old, developed headache, dizziness, memory loss, and slow reaction six months ago. Western medicine diagnosed it as cerebral atrophy. After hospitalization for more than one month of Western medicine treatment, the effect was not obvious, so he switched to Chinese medicine treatment and took the capsules of Example 1, 2 capsules each time, once in the morning and evening. After taking the medicine for 3 consecutive months, the patient's clinical symptoms were significantly improved and his reaction became sensitive.

[0071] Case 3: Mr. Wang, male, 60 years old, was diagnosed with brain atrophy, amnesia, memory loss, right foot hemiplegia, unclear speech, right hand muscle strength level 1, right foot muscle strength level 2 six months ago. He took the capsules of Example 2 twice a day, two capsules each time. After taking it for 4 consecutive months, the patient's amnesia symptoms disappeared, his memory improved, his speech became clear, and he was able to walk with a cane.

[0072] In summary, the peony compatibility capsule provided by the present invention has peony oil, black sesame oil and walnut oil as main ingredients, is rich in nutrition, and has an unsaturated fatty acid content of more than 92%, wherein the unsaturated fatty acid a-linolenic acid is the main element for synthesizing cell membranes, and is an indispensable unsaturated fatty acid that cannot be synthesized or replaced by the human body. The capsule of the present invention not only contains rich DHA, linolenic acid and linoleic acid, but also contains its unique paeonol, peony saponin, peony polysaccharide, fuccosterol, squalene and other nutrients. The composition has the effects of lowering blood lipids and blood pressure, enhancing autoimmunity, treating diabetes, preventing and treating cancer, losing weight, preventing and treating cerebral stroke and myocardial infarction, clearing harmful substances in the blood and preventing and treating heart disease, relieving menopausal syndrome, refreshing the mind and strengthening the brain, enhancing attention and memory, relieving neurasthenia and insomnia, eliminating brain fatigue, improving cerebrovascular function, preventing and treating brain atrophy, assisting in the treatment of multiple sclerosis, assisting in the treatment of rheumatoid arthritis, being used for skin ringworm or eczema, preventing and treating constipation, diarrhea and gastrointestinal syndrome, preventing anemia, activating brain cells, eliminating blood vessel cholesterol, nourishing blood and replenishing qi, and the like.

[0073] The embodiments described above are part of the embodiments of the present invention, rather than all of the embodiments. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

Claims

1. A peony capsule for preventing and treating cerebral atrophy, characterized in that: It includes capsule wall material and active ingredient core material, and the core material includes the following raw materials by weight: 30-50 parts of peony oil, 20-30 parts of black sesame oil, 10-20 parts of walnut oil, 0.01-0.05 parts of selenium source, 1-5 parts of peanut oil, 1-5 parts of Alpinia oxyphylla oil, and 1-5 parts of ginkgo oil.

2. The peony capsule for preventing and treating cerebral atrophy according to claim 1, characterized in that: The core material also includes by weight: 5-10 parts of Gastrodia elata extract, 1-5 parts of Astragalus powder, and 1-5 parts of Angelica sinensis powder.

3. The peony capsule for preventing and treating cerebral atrophy according to claim 2, characterized in that: The core material comprises the following raw materials by weight: 50 parts of peony oil, 30 parts of black sesame oil, 20 parts of walnut oil, 0.05 parts of selenium source, 5 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 5 parts of ginkgo oil, 10 parts of Gastrodia elata extract, 5 parts of astragalus powder, and 5 parts of angelica powder.

4. The peony capsule for preventing and treating cerebral atrophy according to claim 2, characterized in that: The core material comprises the following raw materials by weight: 30 parts of peony oil, 20 parts of black sesame oil, 10 parts of walnut oil, 0.01 parts of selenium source, 1 part of peanut oil, 1 part of Alpinia oxyphylla oil, 1 part of ginkgo oil, 5 parts of Gastrodia elata extract, 1 part of astragalus powder, and 1 part of angelica powder.

5. The peony capsule for preventing and treating cerebral atrophy according to claim 2, characterized in that: The core material comprises the following raw materials by weight: 40 parts of peony oil, 25 parts of black sesame oil, 15 parts of walnut oil, 0.05 parts of selenium source, 3 parts of peanut oil, 5 parts of Alpinia oxyphylla oil, 1 part of ginkgo oil, 8 parts of Gastrodia elata extract, 5 parts of astragalus powder, and 5 parts of angelica powder.

6. The peony capsule for preventing and treating cerebral atrophy according to claim 2, characterized in that: The particle size of the astragalus powder is 10-50um, and the particle size of the angelica powder is 10-50um.

7. The peony capsule for preventing and treating cerebral atrophy according to claim 2, characterized in that: The Gastrodia elata extract is prepared by the following method: The dried Gastrodia elata slices are soaked in water or 10% ethanol aqueous solution for 30-60 minutes and ultrasonically shaken at the same time; then repeatedly freeze-thawed at -10-0°C; reflux extraction is performed, the extract is collected, concentrated and dried into powder, and the Gastrodia elata extract is obtained.

8. A method for preparing the peony capsule for preventing and treating cerebral atrophy according to any one of claims 1 to 7, characterized in that: The following steps are involved: Mix the raw materials of the core material evenly and put them into the capsule wall material.