Control method of NO-containing active gas, gas circuit structure and breathing machine

Abstract

The invention relates to the technical field of medical apparatus and instruments, and particularly discloses a control method of NO-containing active gas, a gas circuit structure and a respirator, comprising a first gas circuit for quantitatively introducing active gas, a second gas circuit for introducing oxygen and a third gas circuit for introducing air, the first gas path, the second gas path and the third gas path are connected with the filtering gas path, and the filtering gas path is connected with the breathing gas path; after being diluted by the stable gas, the active gas is mixed with oxygen and air; or the oxygen and the air are mixed and then mixed with the active gas. Active gas is combined with a gas circuit structure of the breathing machine, so that the active gas is accurately, quantitatively and stably conveyed; the active gas is diluted and then mixed with the oxygen and the air, so that the active gas has stability, the reaction speed of the active gas and the oxygen is reduced, generation of harmful gas is reduced, controllable concentration of the active gas is ensured, and the accuracy of concentration control is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and more specifically to a control method for NO-containing active gas, an air path structure and a ventilator. Background Art

[0002] Gases such as NO (nitric oxide), CO (carbon monoxide) and H2 (hydrogen) have very significant physiological activity on the human body and have positive therapeutic effects on many diseases. However, the human body's demand for these active gases is very small. Exceeding the concentration will cause great toxic side effects, causing great harm to the human body and even death.

[0003] As the mechanism of active gases on human physiology is clarified, active gases such as NO, CO and H2 are increasingly used in the treatment of major human diseases. Taking NO as an example, it is now widely used in the treatment of cardiovascular and cerebrovascular diseases. For this reason, many NO treatment equipment and detection technologies have emerged, but most of these technologies focus on the preparation of nitric oxide. For example, electrolysis and arc discharge methods are used to produce nitric oxide gas, which is then connected to the breathing circuit and then mixed with the oxygen supply circuit of the ventilator to enter the human body to achieve the therapeutic effect. There is also direct use of carbon monoxide medical gas, which is quantitatively controlled and also mixed into the human body through the oxygen supply circuit of the ventilator to achieve the purpose of treatment.

[0004] These devices are characterized by being separate external devices used in conjunction with a ventilator, which have great defects and drawbacks. First, whether it is the electrolysis method or the arc discharge method for preparing nitric oxide, the preparation method is complicated, the waste and harmful gases such as NO2 (nitrogen dioxide) generated are difficult to handle, and the purity of the therapeutic gas is difficult to control. Second, the concentration of nitric oxide gas prepared by the electrolysis method and the arc discharge method is difficult to control, making it even more difficult to control the concentration of the therapeutic gas supplied to the patient after mixing through the ventilator pipeline. The concentration of nitric oxide can only be controlled within a certain range, and the treatment effect cannot be guaranteed. At the same time, there is also the safety hazard of excessive introduction of active gas. Third, most of the existing devices are separate external devices, which are used in conjunction with a ventilator through a pipeline, which affects the treatment effect and safety, and is inconvenient to use.

[0005] The reasons for the above-mentioned defects in the prior art are: first, since the nitric oxide therapeutic gas is used in a very low concentration range, usually at the ppm (parts per million) level, the existing electromagnetic proportional valves and flow sensors cannot be accurately controlled and cannot form a device integrated with the ventilator; second, nitric oxide is a very active reactive gas, which can react rapidly with oxygen to generate nitrogen dioxide gas that is harmful to the human body. This is also a very difficult problem to solve inside the ventilator. Usually, the ventilator is used to allow the patient to inhale oxygen. High concentrations of oxygen and high concentrations of nitric oxide will react rapidly in the ventilator pipeline to form harmful nitrogen dioxide gas, which can cause fatal harm to the patient; third, the prior art mainly adopts the solution of generating nitric oxide or supplying nitric oxide, connecting it close to the inhalation end of the ventilator, and quickly inhaling it into the patient's body.

[0006] Therefore, it is necessary to propose a control method, gas path structure and ventilator containing NO active gas to at least partially solve the problems existing in the prior art. Summary of the invention

[0007] A series of simplified concepts are introduced in the Summary of the Invention, which will be further described in detail in the Detailed Description of the Invention. The Summary of the Invention does not mean to attempt to define the key features and essential technical features of the claimed technical solution, nor does it mean to attempt to determine the scope of protection of the claimed technical solution.

[0008] In order to at least partially solve the above problems, the present invention provides a gas circuit structure containing NO active gas, comprising: a first gas circuit for quantitatively introducing active gas, a second gas circuit for introducing oxygen, and a third gas circuit for introducing air, wherein the first gas circuit, the second gas circuit, and the third gas circuit are connected to a filtering gas circuit, and the filtering gas circuit is connected to a breathing gas circuit;

[0009] The configuration of the first gas path, the second gas path and the third gas path satisfies the following conditions: the active gas is diluted with the stable gas and then mixed with oxygen and air; or, oxygen and air are mixed and then mixed with the active gas.

[0010] Preferably, the first gas circuit comprises: at least one active gas control gas circuit for providing a set amount of active gas;

[0011] The active gas includes one or more of nitric oxide, carbon monoxide and hydrogen.

[0012] Preferably, the first gas circuit further comprises: at least one stabilizing gas control gas circuit for providing a set amount of stabilizing gas;

[0013] The stabilizing gas includes one or more of carbon dioxide and nitrogen.

[0014] Preferably, the ends of the active gas control gas circuit and the stable gas control gas circuit are connected to a first mixed gas circuit;

[0015] The first mixed gas path comprises: a first mixing chamber, a first flow sensor and a first solenoid valve connected in sequence, wherein a first pressure sensor, a stable gas concentration sensor A and an active gas concentration sensor A are arranged in the first mixing chamber;

[0016] The concentration of the active gas in the first mixed gas in the first mixing chamber is detected by the stable gas concentration sensor A and the active gas concentration sensor A, and the active gas control gas path and the stable gas control gas path are controlled so that the concentration of the active gas in the first mixed gas reaches the first set concentration.

[0017] Preferably, the ends of the first gas path and the second gas path are connected to the filtering gas path through the second mixing gas path;

[0018] The second mixed gas path includes: a second mixing chamber, in which an oxygen concentration sensor A, a stable gas concentration sensor B and an active gas concentration sensor B are arranged.

[0019] Preferably, the ends of the second gas path and the third gas path are connected to the filtering gas path through a third mixing gas path.

[0020] Preferably, the filtering gas circuit includes: a third mixing chamber, a first filter, an active gas concentration sensor C, an exhaust gas concentration sensor, an oxygen concentration sensor B, a second flow sensor, a second solenoid valve and a second filter connected in sequence, and a second pressure sensor is provided before the third mixing chamber or in the third mixing chamber; and also includes an exhaust gas collecting bottle for collecting exhaust gas filtered out by the filter.

[0021] A method for controlling NO-containing active gas, comprising:

[0022] A quantitative amount of active gas and a quantitative amount of stable gas are introduced into the first mixing chamber through an active gas control gas path and a stable gas control gas path to obtain a first mixed gas; wherein the first mixed gas contains an active gas of a first set concentration;

[0023] According to a set ratio, the first mixed gas is mixed with oxygen, or the first mixed gas is mixed with a mixed gas of oxygen and air to obtain a second mixed gas;

[0024] The second mixed gas is passed through a filtering gas path, and the oxygen concentration, the active gas concentration and the waste gas concentration are detected in real time. The waste gas is filtered out to obtain the inhaled gas that can be passed into the respiratory gas path.

[0025] Preferably, a quantitative amount of active gas and a quantitative amount of stable gas are introduced into the first mixing chamber through the active gas control gas path and the stable gas control gas path, comprising:

[0026] Detecting the concentration of the active gas in the first mixed gas, and controlling the active gas control gas path and the stable gas control gas path according to the detection result, so that the concentration of the active gas in the first mixed gas reaches a first set concentration;

[0027] The pressure in the first mixing chamber is detected, and the active gas control gas circuit and the stabilizing gas control gas circuit are controlled according to the detection result, so that the pressure in the first mixing chamber is maintained at a set pressure.

[0028] A breathing machine comprises the gas path structure containing NO active gas of the present invention.

[0029] Compared with the prior art, the present invention has at least the following beneficial effects:

[0030] The control method, gas circuit structure and ventilator containing NO in the present invention combine the active gas with the gas circuit structure of the ventilator through various settings of the first gas circuit, the second gas circuit and the third gas circuit, so as to achieve accurate, quantitative and stable delivery of the active gas.

[0031] By diluting the active gas with a stabilizing gas and then mixing it with oxygen and air, the active gas has a certain stability, which greatly reduces the reaction rate of the active gas with oxygen, reduces the generation of harmful gases, ensures that the concentration of the active gas is controllable, and improves the accuracy of active gas concentration control;

[0032] The air circuit of the active gas and the air circuit of the ventilator are integrated and controlled, solving the pain points of nitric oxide therapy equipment.

[0033] The control method, gas circuit structure and ventilator containing NO active gas described in the present invention, and other advantages, objectives and features of the present invention will be reflected in part through the following description, and in part will be understood by technicians in this field through research and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0035] Figure 1 It is a structural schematic diagram of a first arrangement mode of the gas path structure containing NO active gas according to the present invention;

[0036] Figure 2It is a schematic structural diagram of an active gas control gas path, a stabilizing gas control gas path and a first mixed gas path in the gas path structure of NO-containing active gas according to the present invention;

[0037] Figure 3 It is a structural schematic diagram of a second arrangement mode of the gas path structure containing NO active gas according to the present invention;

[0038] Figure 4 It is a structural schematic diagram of an air pump and an air storage chamber on the active gas control gas path in the gas path structure containing NO active gas of the present invention;

[0039] Figure 5 It is a schematic structural diagram of the air pump in the gas path structure containing NO active gas described in the present invention. DETAILED DESCRIPTION

[0040] The present invention is further described in detail below in conjunction with the accompanying drawings and embodiments so that those skilled in the art can implement the invention with reference to the description.

[0041] It should be understood that the terms such as “having”, “including” and “comprising” used herein do not exclude the existence or addition of one or more other elements or combinations thereof.

[0042] like Figure 1-Figure 3 As shown, the present invention provides a gas circuit structure containing NO active gas, comprising: a first gas circuit for quantitatively introducing active gas, a second gas circuit for introducing oxygen, and a third gas circuit for introducing air, wherein the first gas circuit, the second gas circuit, and the third gas circuit are connected to a filtering gas circuit, and the filtering gas circuit is connected to a breathing gas circuit;

[0043] The configuration of the first gas path, the second gas path and the third gas path satisfies the following conditions: the active gas is diluted with the stable gas and then mixed with oxygen and air; or, oxygen and air are mixed and then mixed with the active gas.

[0044] The first gas circuit is used to quantitatively introduce active gas so that a set amount of active gas is mixed with oxygen and air. The mixed gas is filtered through a filter gas circuit to remove harmful gases, i.e., waste gases. The filtered mixed gas enters the respiratory gas circuit and is provided to the patient for inhalation.

[0045] The first gas path, the second gas path and the third gas path include at least the following settings:

[0046] like Figure 1As shown, in the first setting mode, the active gas quantitatively introduced into the first gas path is diluted by the stable gas, first mixed with the oxygen introduced into the second gas path, and then mixed with the air introduced into the third gas path; or, the active gas quantitatively introduced into the first gas path is diluted by the stable gas, the oxygen and air introduced into the second gas path and the third gas path are mixed according to a preset ratio, and then the diluted active gas is mixed with the mixed gas of oxygen and air;

[0047] The advantage of the first setting method is that the quantitatively introduced active gas can first be diluted by the stable gas to reduce the concentration of the active gas. In this way, when the diluted active gas is mixed with oxygen and air, the probability of oxygen and active gas contact can be reduced, the speed of the reaction between the active gas and oxygen can be reduced, and the generation of harmful gases can be reduced; moreover, the concentration of the diluted active gas can be accurately controlled, so that it is convenient to mix with oxygen and air at the first set concentration, thereby improving the accuracy of active gas control.

[0048] like Figure 2 As shown, in the second setting mode, the oxygen and air introduced into the second gas path and the third gas path are mixed according to a preset ratio, and the active gas quantitatively introduced into the first gas path is mixed with the mixed gas of oxygen and air;

[0049] The advantage of the second setting method is that after mixing oxygen and air, the concentration of oxygen is reduced, and then when it is mixed with the quantitatively introduced active gas, the probability of oxygen and active gas contact is reduced, thereby reducing the reaction rate of the two and reducing the generation of harmful gases.

[0050] In one embodiment, the first gas circuit includes: at least one active gas control gas circuit for providing a set amount of active gas;

[0051] The active gas includes one or more of nitric oxide, carbon monoxide and hydrogen.

[0052] Furthermore, the active gas control gas circuit includes: an active gas source 101, a one-way valve A102, a filter A103, a pressure reducing valve A105, an air storage chamber 106, a temperature sensor A107, a pressure sensor A108, an air pump 109, a solenoid valve A110 and a flow sensor A111 connected in sequence; the temperature sensor A107 and the pressure sensor A108 can also be arranged in the air storage chamber 106.

[0053] This embodiment is mainly based on the second setting mode, that is, the active gas is not diluted by the stabilizing gas, and is mixed with the active gas after the oxygen and air are mixed.

[0054] Taking nitric oxide as an example of the active gas, the active gas source 101 is the nitric oxide source. The nitric oxide gas enters the active gas control gas path, passes through the one-way valve A102 and the filter 103 in sequence, and enters the gas storage chamber 106 after the pressure is adjusted by the pressure reducing valve A105. The temperature and pressure of the nitric oxide in the gas storage chamber 106 are detected by the temperature sensor A107 and the pressure sensor A108, and the nitric oxide gas is quantitatively transported by the air pump 109. Then, the flow of the nitric oxide gas is monitored and controlled by the solenoid valve A110 and the flow sensor A111.

[0055] like Figure 5 As shown, further, the air pump 109 includes: a pump body 20, an internal chamber of which is provided with a pump tube 21 and a rotating mechanism 22, both ends of the pump tube 21 are connected to the active gas control air path, and the rotating mechanism 22 is provided with a plurality of rollers 23 evenly spaced along the circumferential direction, and the rollers 23 can roll over the pump tube 21 in sequence after rotation, and the part of the pump tube 21 between the two rollers 23 forms a pump chamber.

[0056] The pump tube 21 is made of elastic material.

[0057] When the air pump 109 is working, by alternately squeezing and releasing the pumped gas on the pump tube 21, the rollers 23 on the rotating mechanism 22 roll over the pump tube 21 in turn, pushing the gas in the pump tube 21 forward. After the rollers 23 roll over, the pump tube 21 returns to its original shape due to its own elasticity, forming a negative pressure at the suction end of the pump tube 21, and the gas is sucked into the pump tube 21 due to the negative pressure;

[0058] During operation, the pump tube 21 between the two rollers 23 forms a pump chamber, the size of which depends on the inner diameter of the pump tube 21 and the size of the rotating mechanism 22 .

[0059] The flow rate of the active gas delivered by the air pump 109 is calculated by the following formula:

[0060]

[0061] Among them, Q stp is the active gas flow rate, k is the flow coefficient, the flow coefficient k is mainly related to the working circle diameter, the number of rollers 23, the diameter of the roller 23, the material of the pump tube 21, the elastic attenuation of the pump tube 21 and other comprehensive factors. The influence of these factors is complex, so they are combined and expressed by the flow coefficient k. The flow coefficient k is a constant under certain conditions; N is the rotation speed of the rotating mechanism 22 (r / min), d is the inner diameter of the pump tube 21 (cm), P is the actual gas pressure, which is obtained by detecting the pressure sensor A108, T is the actual absolute temperature of the gas (actual thermodynamic temperature), which is obtained by detecting the temperature sensor A107, and P n is the air pressure under standard conditions (101325Pa), T nis the thermodynamic temperature of gas under standard conditions (0°C, 273.15K);

[0062] Among them, k·N·d 2 It represents the flow rate Q0 when the gas pressure and temperature are 101.325 kPa and 0°C respectively;

[0063] in, Expressed as flow calculation parameters related to the gas pressure and temperature of the active gas;

[0064] Where ρ is the gas density, ρ n is the gas density under standard conditions (0°C, air density under standard atmospheric pressure is 1.293 kg / m 3 ), through the formula Where Z is the gas compressibility coefficient under actual conditions, Z n is the standard state gas compression coefficient (dimensionless), and in normal indoor temperature environment, the influence of gas compression coefficient can be ignored, so the formula can be obtained So that we can obtain

[0065] like Figure 4 As shown, in order to ensure the accuracy of the active gas flow rate delivered by the air pump 109, a gas storage chamber 106 is set before the air pump 109, which can stabilize the state of the active gas source. The pressure and temperature of the active gas can be obtained through the pressure sensor A108 and the temperature sensor A107, thereby improving the accuracy of the active gas flow rate control delivered by the air pump 109 and realizing quantitative and accurate delivery of the active gas.

[0066] like Figure 1 and Figure 2 As shown, in one embodiment, the first gas circuit further comprises: at least one stabilizing gas control gas circuit, for providing a set amount of stabilizing gas;

[0067] The stabilizing gas includes one or more of carbon dioxide and nitrogen.

[0068] This embodiment is mainly based on the first setting mode, that is, the active gas is diluted by the stable gas and then mixed with oxygen and air.

[0069] Furthermore, the stable gas control gas circuit includes: a stable gas source, a one-way valve B, a filter B, a pressure sensor 1B, a pressure reducing valve B, a pressure sensor 2B, a solenoid valve B, a proportional valve B, a flow sensor B and a pressure sensor 3B connected in sequence.

[0070] Taking nitric oxide as an example of the active gas, the active gas source 101 is a nitric oxide gas source. The nitric oxide gas enters the active gas control gas path, passes through the one-way valve A102 and the filter 103 in sequence, and enters the gas storage chamber 106 after the pressure is adjusted by the pressure reducing valve A105. The temperature and pressure of the nitric oxide in the gas storage chamber 106 are detected by the temperature sensor A107 and the pressure sensor A108, and the nitric oxide gas is quantitatively transported by the air pump 109, and then the flow rate of the nitric oxide gas is monitored and controlled by the solenoid valve A110 and the flow sensor A111;

[0071] Taking carbon dioxide and nitrogen as examples of stable gases, one or two stable gas control gas circuits can be set;

[0072] like Figure 2 As shown, the carbon dioxide control gas circuit includes: a carbon dioxide gas source 201, a one-way valve Ba202, a filter Ba203, a pressure sensor 1Ba204, a pressure reducing valve Ba205, a pressure sensor 2Ba206, a solenoid valve Ba207, a proportional valve Ba208, a pressure sensor 3Ba209 and a flow sensor Ba210 connected in sequence.

[0073] like Figure 2 As shown, the nitrogen control gas circuit includes: a nitrogen gas source 301, a one-way valve Bb302, a filter Bb303, a pressure sensor 1Bb304, a pressure reducing valve Bb305, a pressure sensor 2Bb306, a solenoid valve Bb307, a proportional valve Bb308, a pressure sensor 3Bb309 and a flow sensor Bb310 connected in sequence.

[0074] Assuming that carbon dioxide is used as the stable gas and nitric oxide is used as the active gas, after the quantitatively introduced nitric oxide is mixed with carbon dioxide, the nitric oxide can be diluted and the concentration of nitric oxide can be reduced, which is convenient for accurately controlling the concentration of nitric oxide in the mixed gas, and the two do not react.

[0075] In one embodiment, the ends of the active gas control gas circuit and the stable gas control gas circuit are connected to a first mixed gas circuit;

[0076] The first mixed gas path includes: a first mixing chamber 113, a first flow sensor 116 and a first solenoid valve 117 connected in sequence, and a first pressure sensor 115, a stable gas concentration sensor A112 and an active gas concentration sensor A114 are arranged in the first mixing chamber 113;

[0077] The concentration of the active gas in the first mixed gas in the first mixing chamber 113 is detected by the stable gas concentration sensor A112 and the active gas concentration sensor A114, and the active gas control gas path and the stable gas control gas path are controlled so that the concentration of the active gas in the first mixed gas reaches the first set concentration.

[0078] This embodiment is mainly based on the first setting mode, that is, the active gas is diluted by the stable gas and then mixed with oxygen and air.

[0079] The active gas is nitric oxide as an example, and the stable gas is carbon dioxide as an example. The stable gas concentration sensor A112 is used to detect the carbon dioxide concentration, and the active gas concentration sensor A114 is used to detect the nitric oxide concentration.

[0080] The active gas control gas circuit quantitatively introduces nitric oxide into the first mixing chamber 113, and the stable gas control gas circuit introduces carbon dioxide gas into the first mixing chamber 113. Through real-time detection of nitric oxide and carbon dioxide in the first mixing chamber 113, the active gas control gas circuit (for example, control of the air pump 109 and the solenoid valve A110) and the stable gas control gas circuit (for example, control of the solenoid valve Ba207 and the proportional valve Ba208) are controlled, and the nitric oxide gas concentration in the first mixing chamber 113 is detected and adjusted in real time to make the nitric oxide concentration in the first mixing chamber 113 reach the first set concentration, thereby realizing precise control of the nitric oxide concentration; the pressure in the first mixing chamber 113 is detected by the first pressure sensor 115, and the first mixed gas maintains the set pressure in the first mixing chamber 113. The first mixed gas continues to be transported under the detection and control of the first flow sensor 116 and the first solenoid valve 117.

[0081] like Figure 1 As shown, in one embodiment, the ends of the first gas path and the second gas path are connected to the filtering gas path through the second mixing gas path;

[0082] The second mixed gas path includes: a second mixing chamber 120, in which an oxygen concentration sensor A119, a stable gas concentration sensor B118 and an active gas concentration sensor B121 are disposed.

[0083] The end of the second mixed gas path and the end of the third gas path are both connected to the filtering gas path.

[0084] In this embodiment, preferably, the second gas circuit includes: an oxygen gas source 401, a one-way valve C402, a filter C403, a pressure sensor 1C404, a pressure reducing valve C405, a pressure sensor 2C406, a solenoid valve C407, a proportional valve C408, a pressure sensor 3C409 and a flow sensor C410 connected in sequence.

[0085] The third gas circuit includes: an air source 501, a one-way valve D502, a filter D503, a pressure sensor 1D504, a pressure reducing valve D505, a pressure sensor 2D506, a solenoid valve D507, a proportional valve D508, a pressure sensor 3D509 and a flow sensor D510 connected in sequence.

[0086] This embodiment is mainly based on the first setting method. The first mixed gas in the first mixing chamber 113 enters the second mixing chamber 120 after passing through the first flow sensor 116 and the first solenoid valve 117. At the same time, oxygen also enters the second mixing chamber 120. The two are mixed in the second mixing chamber 120. The oxygen concentration sensor A119, the stable gas concentration sensor B118 and the active gas concentration sensor B121 are respectively used to detect and feedback the oxygen concentration, the stable gas concentration (such as the carbon dioxide concentration) and the active gas concentration (such as the nitric oxide concentration). The mixing ratio is guaranteed by controlling the gas paths where oxygen, carbon dioxide and active gases are located, and then the mixed gas is mixed with air and enters the filtering gas path.

[0087] like Figure 3 As shown, in one embodiment, the ends of the second gas path and the third gas path are connected to the filtering gas path through the third mixing gas path.

[0088] In this embodiment, preferably, the second gas circuit includes: an oxygen gas source 401, a one-way valve C402, a filter C403, a pressure sensor 1C404, a pressure reducing valve C405, a pressure sensor 2C406, a solenoid valve C407, and a proportional valve C408 connected in sequence.

[0089] The third air circuit includes: an air source 501, a one-way valve D502, and a filter D503 connected in sequence.

[0090] The third mixed gas path includes: a turbine 511 and a third flow sensor 512 .

[0091] This embodiment is mainly based on the second setting method, that is, the active gas is not diluted by the stable gas; the oxygen introduced into the second gas path and the air introduced into the third gas path enter the turbine 511 in a preset ratio to mix, so that the oxygen concentration is reduced, and then enter the filtering gas path after passing through the third flow sensor 512, and the active gas is quantitatively introduced through the active gas control gas path, and the active gas enters the filtering gas path, and is mixed with the mixed gas of oxygen and air on the filtering gas path.

[0092] like Figure 1As shown, in one embodiment, the filtering gas circuit includes: a third mixing chamber 5, a first filter 6, an active gas concentration sensor C8, an exhaust gas concentration sensor 9 (such as nitrogen dioxide), an oxygen concentration sensor B10, a second flow sensor 11, a second solenoid valve 12 and a second filter 13 connected in sequence, and a second pressure sensor 6 is provided before the third mixing chamber 5 or in the third mixing chamber 5; and also includes an exhaust gas collecting bottle 14 for collecting exhaust gas (such as nitrogen dioxide and other gases) filtered out by the filter.

[0093] The third mixing chamber 5 contains a first mixed gas (or active gas), air and oxygen to obtain a second mixed gas. Since oxygen and active gases (such as nitric oxide) will produce a small amount of nitrogen dioxide, the nitrogen dioxide can be filtered out by the first filter 6 (a nitrogen dioxide filter can be used), and the nitrogen dioxide concentration is detected by the exhaust gas concentration sensor 9. In order to ensure the filtering effect, the exhaust gas is filtered again by the second filter 13, and the exhaust gas is collected by the exhaust gas collection bottle 14 to obtain gas that can be inhaled by the patient.

[0094] Furthermore, the breathing air circuit includes: a PEEP valve 16 (positive end-expiratory pressure valve), a third pressure sensor 17, a fourth flow sensor 18, an end-expiratory carbon dioxide sensor 19 and a breathing mask connected in sequence; the PEEP valve 16 is provided with an ambient atmosphere connecting device 15.

[0095] The PEEP valve 16 is connected to the end of the second filter 13. The inhaled gas passing through the filter gas path contains active gas. By controlling the respiratory gas path, the inhaled gas is provided to the patient through the breathing mask.

[0096] The present invention also provides a control method for NO-containing active gas, which is applied to the gas path structure containing NO-containing active gas of the present invention, comprising:

[0097] A fixed amount of active gas and a fixed amount of stable gas are introduced into the first mixing chamber 113 through the active gas control gas path and the stable gas control gas path to obtain a first mixed gas; wherein the first mixed gas contains a first set concentration of active gas;

[0098] According to a set ratio, the first mixed gas is mixed with oxygen, or the first mixed gas is mixed with a mixed gas of oxygen and air to obtain a second mixed gas;

[0099] Preferably, the first mixed gas is mixed with oxygen in the second mixing chamber 120 and then mixed with air;

[0100] The second mixed gas is passed through a filtering gas path, and the oxygen concentration, the active gas concentration and the waste gas concentration are detected in real time. The waste gas is filtered out to obtain the inhaled gas that can be passed into the respiratory gas path.

[0101] By detecting the concentration of the active gas in the second mixing chamber 120, the first solenoid valve 117 on the first mixed gas path is controlled in real time so that the concentration of the active gas in the second mixing chamber 120 reaches the second set concentration;

[0102] By detecting the concentration of the active gas on the filter gas path, the first solenoid valve 117 on the first mixed gas path is controlled in real time so that the concentration of the active gas on the filter gas path reaches a third set concentration;

[0103] The third set concentration is lower than the second set concentration, and the second set concentration is lower than the first set concentration.

[0104] Through the above method, gradient dilution of the active gas is achieved, and finally the active gas concentration through the filtered gas path is reduced to the third set concentration, which can reduce the probability of the active gas (such as nitric oxide) reacting with oxygen, and the stabilizing gas has the effect of stabilizing the active gas; through gradient dilution, the concentration of the active gas delivered to the patient can be accurately controlled, the generation of harmful gases can be reduced, and the nitric oxide concentration can be ensured to be controllable.

[0105] Furthermore, a certain amount of active gas and a certain amount of stable gas are introduced into the first mixing chamber 113 through the active gas control gas path and the stable gas control gas path, including:

[0106] Detecting the concentration of the active gas in the first mixed gas, and controlling the active gas control gas path and the stable gas control gas path according to the detection result, so that the concentration of the active gas in the first mixed gas reaches a first set concentration;

[0107] The pressure in the first mixing chamber 113 is detected, and the active gas control gas circuit and the stabilizing gas control gas circuit are controlled according to the detection result, so that the pressure in the first mixing chamber 113 is maintained at a set pressure.

[0108] By detecting, controlling and adjusting the concentration of the active gas, the concentration of the active gas can be controlled. By maintaining the pressure of the first mixing chamber 113 at a set pressure, the stability and accuracy of the active gas delivery can be guaranteed.

[0109] The present invention also provides a breathing machine, comprising the gas path structure containing NO active gas of the present invention.

[0110] The present invention integrates the control of active gases and ventilators, solves the most difficult concentration control problem of active gases (such as nitric oxide), realizes accurate, quantitative and stable gas delivery of active gases such as nitric oxide, and solves the pain points of nitric oxide therapeutic instruments.

[0111] In the description of the present invention, it is to be understood that the terms “center”, “longitudinal”, “lateral”, “length”, “width”, “thickness”, “up”, “down”, “front”, “back”, “left”, “right”, “vertical”, “horizontal”, “top”, “bottom”, “inside”, “outside”, “clockwise”, “counterclockwise”, “axial”, “radial”, “circumferential”, etc., indicating orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0112] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0113] Although the embodiments of the present invention have been disclosed as above, they are not limited to the applications listed in the specification and implementation modes. They can be fully applied to various fields suitable for the present invention. For those familiar with the art, additional modifications can be easily implemented. Therefore, without departing from the general concept defined by the present invention, the present invention is not limited to the specific details and the illustrations shown and described herein.

Claims

1. A gas path structure containing NO active gas, characterized in that: include: A first gas circuit for quantitatively introducing active gas, a second gas circuit for introducing oxygen, and a third gas circuit for introducing air, wherein the first gas circuit, the second gas circuit, and the third gas circuit are connected to a filtering gas circuit, and the filtering gas circuit is connected to a breathing gas circuit; The configuration of the first gas path, the second gas path and the third gas path satisfies the following conditions: the active gas is diluted with the stable gas and then mixed with oxygen and air; or, oxygen and air are mixed and then mixed with the active gas.

2. The gas path structure containing NO active gas according to claim 1, characterized in that: The first gas circuit includes: at least one active gas control gas circuit for providing a set amount of active gas; The active gas includes one or more of nitric oxide, carbon monoxide and hydrogen.

3. The gas path structure containing NO active gas according to claim 2, characterized in that: The first gas circuit further comprises: at least one stabilizing gas control gas circuit for providing a set amount of stabilizing gas; The stabilizing gas includes one or more of carbon dioxide and nitrogen.

4. The gas path structure containing NO active gas according to claim 3, characterized in that: The ends of the active gas control gas circuit and the stable gas control gas circuit are connected with a first mixed gas circuit; The first mixed gas path comprises: a first mixing chamber, a first flow sensor and a first solenoid valve connected in sequence, wherein a first pressure sensor, a stable gas concentration sensor A and an active gas concentration sensor A are arranged in the first mixing chamber; The concentration of the active gas in the first mixed gas in the first mixing chamber is detected by the stable gas concentration sensor A and the active gas concentration sensor A, and the active gas control gas path and the stable gas control gas path are controlled so that the concentration of the active gas in the first mixed gas reaches the first set concentration.

5. The gas path structure containing NO active gas according to claim 2 or 3, characterized in that: The ends of the first gas path and the second gas path are connected to the filtering gas path through the second mixing gas path; The second mixed gas path includes: a second mixing chamber, in which an oxygen concentration sensor A, a stable gas concentration sensor B and an active gas concentration sensor B are arranged.

6. The gas path structure containing NO active gas according to claim 2 or 3, characterized in that: The ends of the second gas path and the third gas path are connected to the filtering gas path through the third mixing gas path.

7. The gas path structure containing NO active gas according to claim 1, characterized in that: The filtering gas circuit includes: a third mixing chamber, a first filter, an active gas concentration sensor C, an exhaust gas concentration sensor, an oxygen concentration sensor B, a second flow sensor, a second solenoid valve and a second filter connected in sequence; a second pressure sensor is provided before the third mixing chamber or in the third mixing chamber; and also includes an exhaust gas collecting bottle for collecting the exhaust gas filtered out by the filter.

8. A method for controlling NO-containing active gas, applied to the gas path structure containing NO-containing active gas according to any one of claims 1 to 7, characterized in that: include: A quantitative amount of active gas and a quantitative amount of stable gas are introduced into the first mixing chamber through an active gas control gas path and a stable gas control gas path to obtain a first mixed gas; wherein the first mixed gas contains an active gas of a first set concentration; According to a set ratio, the first mixed gas is mixed with oxygen, or the first mixed gas is mixed with a mixed gas of oxygen and air to obtain a second mixed gas; The second mixed gas is passed through a filtering gas path, and the oxygen concentration, the active gas concentration and the waste gas concentration are detected in real time. The waste gas is filtered out to obtain the inhaled gas that can be passed into the respiratory gas path.

9. The method for controlling NO-containing active gas according to claim 8, characterized in that: A quantitative amount of active gas and a quantitative amount of stable gas are introduced into the first mixing chamber through the active gas control gas path and the stable gas control gas path, including: Detecting the concentration of the active gas in the first mixed gas, and controlling the active gas control gas path and the stable gas control gas path according to the detection result, so that the concentration of the active gas in the first mixed gas reaches a first set concentration; The pressure in the first mixing chamber is detected, and the active gas control gas circuit and the stabilizing gas control gas circuit are controlled according to the detection result, so that the pressure in the first mixing chamber is maintained at a set pressure.

10. A ventilator, characterized in that: A gas path structure containing NO active gas comprising any one of claims 1-7.

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