Metagen casein hydrolyzed peptide solid beverage capable of improving sleep quality

By adopting multiple pathway synergistic mechanisms of multiple components such as epigenetic casein hydrolyzed peptides in sleep aid solid beverages, the problem of single regulatory factors and insignificant efficacy of existing sleep aid products is solved, and the full-link sleep intervention and sensory experience improvement is achieved, which significantly improves sleep quality.

CN119867238APending Publication Date: 2025-04-25HEBEI JIDONG BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202510303802.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-14
Publication Date
2025-04-25

AI Technical Summary

Technical Problem

The existing sleep-aided solid beverages have single regulatory factors, with less obvious efficacy, poor palatability, and poor sensory experience, making it difficult to comprehensively improve sleep quality.

Method used

The solid beverage of epizonomic casein hydrolyzed peptide is adopted to integrate neurotransmitter regulation, intestinal-brain axis action and sensory experience optimization through a multi-path collaborative mechanism, including the combination of components such as γ-aminobutyric acid, casein hydrolyzed peptide, walnut peptide, jujube seed powder, poria powder, lily powder, lotus seed powder, fructose oligooligosaccharide, galactose oligooligosaccharide, resistant dextrin, double-petal rose fruit powder and sour cherry powder.

Benefits of technology

A full-link sleep intervention from neurotransmitter regulation to metabolic optimization is achieved, covering most factors that cause sleep disorders, significantly improving sleep quality, improving sensory experience, and suitable for a variety of people.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to a mesogen casein hydrolyzed peptide solid beverage for improving sleep quality, which comprises the following components in parts by mass: 15-50 parts of a neurotransmitter regulator, 200-400 parts of an intestinal tract-brain axis regulator, 30-80 parts of a medicinal and edible herbal multi-target regulator, 100-240 parts of a flavor and metabolism regulator and 1-5 parts of an antioxidant, the neurotransmitter regulator is a combination of any two or more of gamma-aminobutyric acid, phosphatidylserine and walnut peptide; the intestinal tract-brain axis regulator comprises a metagen, casein hydrolyzed peptide and a prebiotic; the medicinal and edible herbal multi-target regulator is at least one of spina date seed powder, poria cocos powder, lily powder and lotus seed powder; the flavor and metabolism regulator at least comprises double-petal rose fruit powder and a sweetening agent. According to the traditional Chinese medicine composition disclosed by the invention, the sleep aiding effect is comprehensively and synergistically exerted through four paths of neurotransmitter regulation and control, intestine-brain axis optimization, herbal multi-target intervention and sensory synergy. The Pesenberg sleep index scale survey shows that the solid beverage disclosed by the invention has a very good sleep aiding effect.
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Description

Technical Field

[0001] The invention belongs to the technical field of food processing, and in particular relates to a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality. Background Art

[0002] Sleep disorders are extremely harmful to the human body. In mild cases, it can cause a loss of concentration and have a negative impact on work and study. In severe cases, it can affect the normal functioning of the brain and the body's immune defense capabilities. Even every high-risk major disease is inseparable from the lack of sleep. The sudden death rate caused by sleep problems is much higher than that of people with normal sleep. According to surveys and studies, the main causes of sleep disorders are neurotransmitter disorders (decreased function of γ-aminobutyric acid receptors, imbalance in 5-HT circadian secretion), changes in hormone levels, abnormal cortisol rhythm, chronic stress, anxiety and depression, circadian rhythm reversal and hidden diseases. Research by Matthew Walker, director of the Center for Human Sleep Science at the University of California, Berkeley, shows that long-term lack of sleep can induce a variety of diseases, such as hypertension, diabetes, depression, obesity, cardiovascular and cerebrovascular diseases, and other diseases. Therefore, it is urgent to improve sleep quality. At present, the drugs used to treat insomnia are mainly Western medicine and Chinese medicine. Western medicine is often accompanied by unclear effects, long-term medication, high drug dependence, and large side effects. Long-term use may cause harm to the kidneys or liver. Traditional Chinese medicine sleep aid products are expensive and often have poor palatability. Therefore, developing functional foods that can be consumed daily and for a long time is more in line with the needs of modern society to fight against anxiety caused by high stress and improve sleep quality.

[0003] For example, CN115226773A discloses a composite probiotic sleep-aiding solid beverage and a preparation method, which contains 20.03-60.03 parts of whole milk powder, 1-2 parts of tea theanine, 4-5 parts of γ-aminobutyric acid, 0.20 parts of vitamin C, 2-5 parts of composite probiotics, 16.02-36.02 parts of inulin, 5.01-15.01 parts of oligofructose, 7.01-17.01 parts of erythritol (sweetener), thickener and flavor. Among them, γ-aminobutyric acid, tea theanine and whole milk powder are all amino acids or protein components, inulin and oligofructose are prebiotics, so the effective ingredients of the scheme are actually only amino acids, probiotics and prebiotics, and the types of effective ingredients are relatively single, and it is difficult to comprehensively and comprehensively affect and regulate the various factors that cause sleep disorders, so the scheme has limited effect on improving sleep quality. In addition, the product contains a high amount of whole milk powder, which is not suitable for people who are intolerant to dairy products or those who pursue low-calorie, low-fat intake. The formula is extremely thin in terms of taste, using only erythritol sweetener, the taste is not rich enough, which is not conducive to market promotion, and the sensory experience needs to be further optimized.

[0004] In view of the above problems, the present invention hopes to propose an improved solution. Summary of the invention

[0005] 1. Technical issues to be resolved

[0006] In view of the above-mentioned shortcomings and deficiencies of the prior art, the present invention provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, which integrates neurotransmitter regulation, gut-brain axis action and sensory experience optimization through a multi-pathway synergistic mechanism, and further proposes a sleep-aiding solid beverage with a more scientific formula and better market adaptability, which solves the technical problems of existing similar products such as single regulatory factors, unclear efficacy, poor palatability and poor sensory experience.

[0007] (II) Technical solution

[0008] In a first aspect, the present invention provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, which comprises, by weight: 15-50 parts of a neurotransmitter regulator, 200-400 parts of a gut-brain axis regulator, 30-80 parts of a medicinal and edible herbal multi-target regulator, 100-240 parts of a flavor and metabolism regulator, and 1-5 parts of an antioxidant;

[0009] Among them, the neurotransmitter regulator is a combination of any two or three of γ-aminobutyric acid, phosphatidylserine and walnut peptide; the gut-brain axis regulator contains postbiotics, casein hydrolyzed peptides and prebiotics, and the prebiotics are at least one of oligofructose, oligogalactose and resistant dextrin; the herbal multi-target regulator with medicinal and edible properties is at least one of sour jujube seed powder, poria powder, lily powder and lotus seed powder; the flavor and metabolic regulator at least contains double rose fruit powder and sweetener.

[0010] According to a preferred embodiment of the present invention, the neurotransmitter regulator is obtained by mixing γ-aminobutyric acid, phosphatidylserine and walnut peptide in a mass ratio of 5-10:5-10:15-20.

[0011] According to a preferred embodiment of the present invention, the gut-brain axis regulator is obtained by mixing postbiotics, casein hydrolyzed peptides and prebiotics in a mass ratio of 5-10:1-2:10-15.

[0012] According to a preferred embodiment of the present invention, the prebiotics are obtained by mixing fructooligosaccharides, galacto-oligosaccharides and resistant dextrin in a mass ratio of 4-6:3-5:3-5.

[0013] According to a preferred embodiment of the present invention, the herbal multi-target regulator with medicinal and edible properties is obtained by mixing spiny jujube seed powder, tuckahoe powder, lily powder and lotus seed powder in a mass ratio of 10-15:3-6:2-4:2-4.

[0014] According to a preferred embodiment of the present invention, the flavor and metabolism regulator is obtained by mixing double rose fruit powder, sour cherry powder, and sweetener in a mass ratio of 6-10:3-5:5-8.

[0015] According to a preferred embodiment of the present invention, the sweetener is obtained by mixing polydextrose and steviol glycoside in a mass ratio of 50-80:1-5.

[0016] According to a preferred embodiment of the present invention, the antioxidant is L-ascorbic acid.

[0017] In a second aspect, the present invention provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality. Measured by mass, every 500 portions of the solid beverage include: 2-15 portions of γ-aminobutyric acid, 3-15 portions of phosphatidylserine, 10-100 portions of walnut peptides, 50-100 portions of postbiotics, 10-30 portions of casein hydrolyzed peptides, 30-80 portions of oligofructose, 30-60 portions of galacto-oligosaccharides, 30-60 portions of resistant dextrin, 15-40 portions of sour jujube kernel powder, 5-15 portions of poria powder, 5-15 portions of lily powder, 5-15 portions of lotus seed powder, 50-100 portions of double rose fruit powder, 40-60 portions of sour cherry powder, 40-90 portions of polydextrose, 1-5 portions of stevioside, and 1-5 portions of L-ascorbic acid.

[0018] (III) Beneficial effects

[0019] The solid beverage of the present invention is different from the prior art. It does not contain a large amount of whole milk powder, but uses casein hydrolyzed peptides that are easy to absorb and utilize, does not contain fat, and broadens the applicable population of the product. The solid beverage of the present invention starts with the regulation of neurotransmitters, the gut-brain axis, metabolism and other aspects, comprehensively achieves the purpose of improving sleep quality, covers most of the factors that cause sleep disorders, and effectively enhances the efficacy of the product. At the same time, the present invention also uses herbal medicinal materials that are both medicinal and edible to fundamentally regulate the body and immunity, thereby consolidating the improvement of sleep. In addition, the present invention adds double-petal rose fruit powder, sour cherry powder and other ingredients with special flavor regulation and inhibition of sympathetic nerve excitement, anti-depression and other effects, which not only helps to improve the user's sleep experience pleasure, but also makes the product taste richer, enhances the sensory experience, and is conducive to the market promotion of the product.

[0020] The present invention relates to a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, wherein the formula of the beverage combines a variety of ingredients that help sleep, including: amino acid ingredients (such as γ-aminobutyric acid (GABA) and phosphatidylserine), which can promote the release of inhibitory neurotransmitters and help relax the nervous system; sleep-promoting small molecule peptides (such as casein hydrolyzed peptides and walnut peptides) assist in improving sleep quality through a variety of mechanisms; medicinal and edible biologically active ingredients (such as jujube seeds, tuckahoe powder, lily powder and lotus seed powder) contain jujube seed saponins and proanthocyanidin B-2, which help regulate nerve function and promote sleep; prebiotics (such as oligofructose, oligogalactose and resistant dextrin) can promote the growth of beneficial intestinal flora and support sleep through the mechanism of action of the gut-brain axis. Postbiotics can utilize the secondary metabolites produced by probiotics, avoid the need for the number of live bacteria, and directly provide a sleep-promoting effect. Double rose fruit powder and sour cherry powder not only increase the flavor of the beverage, but also contain aromatic substances that help sleep and regulate emotions.

[0021] In summary, the solid beverage of the present invention promotes sleep quality from multiple perspectives through the synergistic effect of the above ingredients, including regulating the nervous system, increasing the release of inhibitory neurotransmitters, optimizing the intestinal microbial environment and the influence of its metabolites. According to the Pittsburgh Sleep Quality Index (PSQI) survey results, this beverage has a significant sleep-inducing effect, indicating that it has good market promotion value. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 The PSQI changes after the samples of Example 1 were taken by three groups of people, young, middle-aged and old, for 2 weeks.

[0023] Figure 2 The PSQI changes after the sample of comparative example 1 was taken by three groups of young, middle-aged and elderly people for 2 weeks.

[0024] Figure 3 The PSQI changes of the samples of comparative example 2 after being taken by three groups of young, middle-aged and elderly people for 2 weeks.

[0025] Figure 4 The PSQI changes after the samples of comparative example 3 were taken by three groups of young, middle-aged and elderly people for 2 weeks.

[0026] Figure 5 The PSQI changes of the samples of comparative example 4 after being taken by three groups of young, middle-aged and elderly people for 2 weeks.

[0027] Figure 6 The PSQI changes after the samples of Examples 1-4 were taken by a middle-aged group for 2 weeks. DETAILED DESCRIPTION

[0028] The present invention constructs a scientific sleep-aiding system through the coordination of neurotransmitter regulation, gut-brain axis optimization, herbal multi-target intervention and sensory enhancement quadruple pathways, and adds γ-aminobutyric acid, casein hydrolyzed peptides, walnut peptides, jujube seeds, Poria powder, lily powder, lotus seed powder, oligofructose, oligogalactose, resistant dextrin, postbiotics, double rose fruit powder, and sour cherry powder to the solid beverage, which includes both inhibitory neurotransmitters and amino acids and bioactive ingredients such as jujube seed saponins and proanthocyanidin B-2 that promote the release of inhibitory neurotransmitters, promote intestinal flora to utilize prebiotics and postbiotics, degrade prebiotics or postbiotics into short-chain fatty acids, and enable the gut-brain axis to play a role in supporting sleep; add rose fruit powder, etc., provide sleep-aiding aromatic substances, which are used to cheer up, regulate emotions, relieve anxiety and depression, etc., thereby comprehensively and collaboratively exerting the sleep-aiding effect. The experiment of the present invention also proves that the solid beverage has a good sleep-aiding effect through the Pitsonburg Sleep Index Scale survey.

[0029] Neurotransmitter regulator: Gamma-aminobutyric acid plays a direct role in regulating neurotransmitters, directly activating GABA-A receptors, inhibiting excessive neuronal discharge, and reducing the proportion of EEG beta waves (awakening waves). Phosphatidylserine PS is used to enhance brain cell membrane fluidity, promote acetylcholine synthesis (enhance memory-related theta wave activity), and indirectly relieve anxiety-related insomnia. Walnut peptides contain antioxidant peptides (such as Walnut peptide-3), which inhibit microglial inflammatory factors (such as TNF-α, etc.) and protect neurons from oxidative damage.

[0030] Gut-brain axis regulators: Postbiotics are inactivated bacterial metabolites (such as lipoteichoic acid), which can activate TLR2 receptors, promote IL-10 secretion (anti-inflammatory factor), and reduce intestinal sleep disturbances. Casein hydrolyzed peptides can release β-casomorphin-7, inhibit the upload of intestinal pain signals through μ-opioid receptors, and reduce the frequency of night awakenings. Fructooligosaccharides and galacto-oligosaccharides increase the proliferation rate of bifidobacteria in the intestine, improve the efficiency of tryptophan conversion to 5-HT, promote melatonin synthesis, and play a sleep-inducing effect. Resistant dextrin can be slowly fermented in the intestine to produce butyric acid (colon concentration ≥20mM), activate vagus nerve afferent fibers, and enhance NREM sleep duration.

[0031] Multi-target synergist of medicinal and edible herbs: Jujube saponin A contained in jujube seed powder inhibits hypothalamic CRH release, reduces serum cortisol levels (decreases at night), and shortens sleep latency. Poria polysaccharide (PCP-2) regulates Th1 / Th2 balance and reduces IL-6-mediated inflammatory sleep disruption. Lilium saponin and liensinine synergistically activate 5-HT1A receptors and improve sleep maintenance stability (reduce the number of awakenings).

[0032] Flavor and metabolic regulator: Linalool in double rose fruit powder activates the parasympathetic nerves through the olfactory receptor OR2J3, reducing the heart rate variability (HRV) LF / HF ratio. Sour cherry powder is rich in natural melatonin precursors (0.2μg / g), which can accurately match the human body's secretion rhythm and increase the peak concentration of salivary melatonin. Polydextrose has water retention (4g water / g), which can prolong gastric emptying time and prevent blood sugar fluctuations from interfering with sleep.

[0033] Among them, GABA is used in combination with casein peptides: GABA directly inhibits central excitability, casein peptides enhance peripheral opioid signals through the gut-brain axis, doubly reduce wakefulness drive (reduce PSQI scores), and GABA and casein peptides cover the central-peripheral dual pathways. Postbiotics and prebiotics are used in combination: postbiotics (inactivated bacteria) activate immune regulation, prebiotics (oligofructose / galactose) promote the production of SCFAs by the bacterial flora, synergistically improve 5-HT conversion efficiency, and increase intestinal 5-HT concentration. γ-Aminobutyric acid, casein peptides, postbiotics, and prebiotics form a neural-gut-brain signal linkage mechanism.

[0034] Combination of sour jujube seed powder and sour cherry powder: Sour jujube seed saponin A inhibits excessive activation of the HPA axis, and sour cherry melatonin precursor synchronously strengthens the pineal gland function, optimizing the amplitude of the cortisol / melatonin circadian rhythm. Combination of Poria cocos and lily: Poria cocos polysaccharide reduces the interference of inflammatory factors, lily saponin enhances the activity of GABAergic neurons, and multiple targets prolong the deep sleep period. Sour jujube seeds, sour cherries, Poria cocos and lilies form a synergistic effect of metabolic rhythm.

[0035] Rose and polydextrose combined: Rose fragrance quickly induces a state of relaxation (usually takes effect in 15 minutes), polydextrose slowly releases energy to maintain blood sugar homeostasis, rose rapid induction + sour cherry powder long-term regulation, forming a "rapid induction-long-term maintenance" sleep guarantee. Stevioside combined with resistant dextrin: Stevioside masks the bitter taste of herbs (palatability score ≥8.5 / 10), resistant dextrin increases satiety and reduces hunger awakening at night. Rose, polydextrose, stevioside, and resistant dextrin form a sensory-physiological reflex synergy.

[0036] Resistant dextrin is both an auxiliary material (filler) and a prebiotic. It is made from starch through a specific processing process. The human digestive enzymes have difficulty breaking down this modified starch component. Because of this, resistant dextrin can reach the large intestine intact and become food for intestinal flora, especially for promoting the growth of beneficial bacteria such as bifidobacteria and lactic acid bacteria. This type of substance helps to improve the intestinal microbial environment and promote the production of short-chain fatty acids, which in turn brings a variety of health benefits, such as improving intestinal function and enhancing immunity.

[0037] The solid beverage of the present invention realizes the full-link sleep intervention from neural regulation to metabolic optimization. The natural ingredients in the solid beverage account for more than 95%, which is in line with the general trend of healthy food.

[0038] In order to better explain the present invention and facilitate understanding, the present invention is described in detail below through specific implementation modes in conjunction with the accompanying drawings.

[0039] Example 1

[0040] This embodiment provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, and the preparation method thereof is as follows:

[0041] (1) Accurately weigh according to the following formula

[0042] Table 1:

[0043]

[0044] (2) Mix the above raw materials at a mixer speed of 35 Hz for 30 minutes and pack them. Packaging working parameters: transverse sealing temperature is 100-140°C, longitudinal sealing temperature is 100-140°C, and the filling amount is set to 5g / bag. The average weight is 4.75-5.25g, the weight difference should be controlled within ±5%, and the average filling amount is not less than 5g / bag.

[0045] Example 2

[0046] This embodiment provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, the composition of which is shown in Table 2 below, and the preparation method is the same as that of Example 1.

[0047] Table 2:

[0048]

[0049] Example 3

[0050] This embodiment provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, the composition of which is shown in Table 3 below, and the preparation method is the same as that of Example 1.

[0051] Table 3:

[0052]

[0053] Example 4

[0054] This embodiment provides a postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, the composition of which is shown in Table 4 below, and the preparation method is the same as that of Example 1.

[0055] Table 4:

[0056]

[0057] Comparative Example 1

[0058] This comparative example is based on Example 1, and the following adjustments are made: the postbiotic component of the intestinal-brain axis regulator is removed, the casein hydrolyzed peptide is adjusted to 30 kg, the oligofructose is adjusted to 90 kg, and the oligogalactose is adjusted to 85 kg. The rest of the ingredients are exactly the same as in Example 1.

[0059] Comparative Example 2

[0060] This comparative example is based on Example 1, with the following adjustments: the casein hydrolyzed peptide component is removed from the intestinal-brain axis regulator, and the oligofructose is adjusted to 55 kg. The rest of the ingredients are exactly the same as those in Example 1.

[0061] Comparative Example 3

[0062] This comparative example is based on Example 1, with the following adjustments: only γ-aminobutyric acid is retained as the neurotransmitter regulator, and its dosage is increased to 25 kg. The rest of the components are exactly the same as those in Example 1.

[0063] Comparative Example 4

[0064] This comparative example is based on Example 1, and the following adjustments are made: the herbal multi-target regulator of medicinal and edible origin is removed as a whole, the amount of oligofructose is increased to 77kg, and the amount of 75kg double-petal rose fruit is increased to 95kg. The rest of the ingredients are exactly the same as those in Example 1.

[0065] Pitsonburg Sleepiness Index

[0066] 1. Test methods

[0067] The improvement of sleep quality of different groups of people was investigated by Example 1 and Comparative Examples 1-4. The subjects were required to fill in the Pitsonburg Sleepiness Index scale before and after taking the product of the present invention and the samples of Comparative Examples 1-4 for 2 weeks. The dosage was 5-10 g / day.

[0068] 2. Grouping

[0069] The experiment was divided into 5 groups: Example 1: young and middle-aged group (18-40 years old), middle-aged group (41-59 years old); elderly group (over 60 years old); comparative example 1: young and middle-aged group (18-40 years old), middle-aged group (41-59 years old); elderly group (over 60 years old); comparative example 2: young and middle-aged group (18-40 years old), middle-aged group (41-59 years old); elderly group (over 60 years old); comparative example 3: young and middle-aged group (18-40 years old), middle-aged group (41-59 years old); elderly group (over 60 years old); comparative example 4: young and middle-aged group (18-40 years old), middle-aged group (41-59 years old); elderly group (over 60 years old). Each group took the product for two weeks, half an hour before going to bed, for 2 consecutive weeks.

[0070] 3. Pittsburgh sleep survey experiment, the results are shown in Table 5.

[0071] Table 5: Effectiveness results of the subjects after taking Example 1 and Comparative Examples 1-4

[0072]

[0073] As shown in Table 5, the effectiveness of this product in improving sleep is over 80%, while the effectiveness of the comparative example is only 10%-40%.

[0074] Results of follow-up survey on sleep improvement of Example 1 and Comparative Examples 1-4

[0075] Table 6: Youth Group

[0076]

[0077]

[0078] Table 7: Middle-aged group

[0079]

[0080]

[0081] Table 8: Elderly group

[0082]

[0083]

[0084]

[0085] The Pitsonburg Sleep Quality Index (PSQI) in Tables 5 to 8 above reflects the sleep quality, sleep time, sleep time, sleep efficiency, sleep disorders, hypnotic drugs and daytime dysfunction in the past two weeks. The scoring scale is: 0-5 points, very good sleep quality; 5-10 points, good sleep quality; 11-15 points, average sleep quality; 16-21 points, very poor sleep quality. The results are as follows Figure 1 shown.

[0086] Depend on Figure 1 It can be seen that after the youth group took the sample of Example 1 for 2 weeks, the PSQI index decreased from 6.8 points to 3.6 points, a decrease of 47.06%, and the sleep quality improved from OK to good; after the middle-aged group took it for 2 weeks, the PSQI index decreased from 11.6 points to 6.2 points, a decrease of 46.55%, and the sleep quality improved from general to OK; after the elderly group took it for 2 weeks, the PSQI index decreased from 12.8 points to 6.2 points, a decrease of 51.56%, and the sleep quality decreased from general to OK.

[0087] Depend on Figure 2 It can be seen that after the youth group took the sample of comparative example 1 for 2 weeks, the PSQI index decreased from 6.8 to 6.2, a decrease of 8.8%; after the middle-aged group took it for 2 weeks, the PSQI index decreased from 12 points to 10.5 points, a decrease of 12.5%; after the elderly group took it for 2 weeks, the PSQI index decreased from 13.5 points to 11 points, a decrease of 18.5%. Although the sleep conditions of the three age groups were slightly improved, the sleep levels did not change.

[0088] Depend on Figure 3 It can be seen that after the youth group took the sample of comparative example 2 for 2 weeks, the PSQI index decreased from 6.5 to 6.0, a decrease of 7.7%; after the middle-aged group took it for 2 weeks, the PSQI index decreased from 11.7 points to 10.5 points, a decrease of 10.3%; after the elderly group took it for 2 weeks, the PSQI index decreased from 13.3 points to 11.2 points, a decrease of 15.79%. Although the sleep conditions of the three age groups were slightly improved, the sleep levels did not change.

[0089] Depend on Figure 4 It can be seen that after the youth group took the sample of comparative example 3 for 2 weeks, the PSQI index decreased from 6.7 to 5.9, a decrease of 11.9%; after the middle-aged group took it for 2 weeks, the PSQI index decreased from 12.1 points to 10.2 points, a decrease of 15.7%; after the elderly group took it for 2 weeks, the PSQI index decreased from 13.5 points to 10.1 points, a decrease of 25.2%. Although the sleep conditions of the three age groups were slightly improved, the sleep levels did not change.

[0090] Depend on Figure 5It can be seen that after the youth group took the sample of comparative example 4 for 2 weeks, the PSQI index decreased from 7.0 to 6.4, a decrease of 8.6%; after the middle-aged group took it for 2 weeks, the PSQI index decreased from 11.9 points to 10.2 points, a decrease of 14.3%; after the elderly group took it for 2 weeks, the PSQI index decreased from 14.1 points to 11 points, a decrease of 22.0%. Although the sleep conditions of the three age groups were slightly improved, the sleep levels did not change.

[0091] In summary, Example 1 improves the sleep condition of people of different age groups, and the effect is best for the elderly group. However, Comparative Examples 1-4 have no obvious effect on improving the sleep of people with sleep disorders in the three age groups.

[0092] Depend on Figure 6 It can be seen that the samples of Examples 1-4 were taken by the middle-aged group for 2 weeks. Figure 6 As shown, after taking the sample of Example 1 for 2 weeks, the PSQI index of the middle-aged group decreased from 11.6 points to 6.2 points, a decrease of 46.55%, and the sleep quality improved from general to good; after taking the sample of Example 2 for 2 weeks, the PSQI index of the middle-aged group decreased from 11.8 points to 7.8 points, a decrease of 33.9%; after taking the sample of Example 3 for 2 weeks, the PSQI index of the middle-aged group decreased from 11.7 points to 7.9 points, a decrease of 32.5%; after taking the sample of Example 4 for 2 weeks, the PSQI index of the middle-aged group decreased from 12.1 points to 8.1 points, a decrease of 33.1%.

[0093] In summary, the samples of Example 1 and Examples 2-4 can achieve good sleep quality improvement effects after being taken by the middle-aged group for 2 weeks. Among the above examples, the sample of Example 1 is proven to have the best effect on improving sleep quality.

[0094] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that the technical solutions described in the above embodiments may still be modified, or some or all of the technical features therein may be replaced by equivalents. These modifications or replacements, or the technical features in the above embodiments may be combined in the manner described in the embodiments if they do not conflict with each other, and these modifications, replacements or combinations do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, characterized in that: By weight, it contains: 15-50 parts of neurotransmitter regulators, 200-400 parts of gut-brain axis regulators, 30-80 parts of medicinal and edible herbal multi-target regulators, 100-240 parts of flavor and metabolism regulators and 1-5 parts of antioxidants; Among them, the neurotransmitter regulator is a combination of any two or three of γ-aminobutyric acid, phosphatidylserine and walnut peptide; the gut-brain axis regulator contains postbiotics, casein hydrolyzed peptides and prebiotics, and the prebiotics are at least one of oligofructose, oligogalactose and resistant dextrin; the herbal multi-target regulator with medicinal and edible properties is at least one of sour jujube seed powder, poria powder, lily powder and lotus seed powder; the flavor and metabolic regulator at least contains double rose fruit powder and sweetener.

2. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 1, characterized in that: The neurotransmitter regulator is obtained by mixing gamma-aminobutyric acid, phosphatidylserine and walnut peptide in a mass ratio of 5-10:5-10:15-20.

3. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 1, characterized in that: The intestinal-brain axis regulator is obtained by mixing postbiotics, casein hydrolyzed peptides and prebiotics in a mass ratio of 5-10:1-2:10-15.

4. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 3, characterized in that: The prebiotics are obtained by mixing fructooligosaccharide, galacto-oligosaccharide and resistant dextrin in a mass ratio of 4-6:3-5:3-5.

5. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 1, characterized in that: The herbal multi-target regulator of medicinal and edible properties is obtained by mixing sour jujube seed powder, tuckahoe powder, lily powder and lotus seed powder in a mass ratio of 10-15:3-6:2-4:2-4.

6. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 1, characterized in that: The flavor and metabolism regulator is obtained by mixing double rose fruit powder, sour cherry powder and a sweetener in a mass ratio of 6-10:3-5:5-8.

7. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 6, characterized in that: The sweetener is obtained by mixing polydextrose and stevioside in a mass ratio of 50-80:1-5.

8. The postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality according to claim 1, characterized in that: The antioxidant is L-ascorbic acid.

9. A postbiotic casein hydrolyzed peptide solid beverage for improving sleep quality, characterized in that: Measured by mass, every 500 portions of solid beverage include: 3-10 portions of γ-aminobutyric acid, 3-10 portions of phosphatidylserine, 10-30 portions of walnut peptide, 50-100 portions of postbiotics, 10-30 portions of casein hydrolyzed peptide, 30-80 portions of fructooligosaccharides, 30-60 portions of galacto-oligosaccharides, 30-60 portions of resistant dextrin, 15-40 portions of spinosad seed powder, 5-15 portions of poria powder, 5-15 portions of lily powder, 5-15 portions of lotus seed powder, 50-100 portions of double rose fruit powder, 40-60 portions of sour cherry powder, 40-90 portions of polydextrose, 1-5 portions of stevioside, and 1-5 portions of L-ascorbic acid.