Traditional Chinese medicine composition for treating female climacteric syndrome and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating female climacteric syndrome and application thereof. The traditional Chinese medicine composition is prepared from cockscomb, flos puerariae, flos sophorae, Chinese forest frog, rhodiola rosea, rhizoma cimicifugae, chrysanthemum, lotus plumule and fructus cnidii. The medicine further comprises menthol and sweet white spirit. The preparation of the traditional Chinese medicine composition is prepared by the following steps: extracting celosia cristata, pueraria flower, sophora flower, Chinese forest frog, rhodiola rosea, cimicifuga foetida, chrysanthemum, lotus plumule and fructus cnidii by a solvent extraction method, and concentrating into extract; and uniformly mixing the extract with menthol and sweet white spirit to prepare an oral solution. The obtained medicine has the effects of clearing away heart-fire, relieving restlessness, enriching yin, nourishing kidney, calming and cooling blood; the preparation disclosed by the invention is scientific and reasonable in formula compatibility, quick in effect taking and free from toxic and side effects, and has a very excellent treatment effect on the female climacteric syndrome.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and mainly relates to a traditional Chinese medicine composition for treating female menopausal syndrome and application thereof. Background Art

[0002] Female menopausal syndrome, also known as various symptoms before and after menopause, refers to a series of symptoms in women before and after menopause, such as menstrual disorders or cessation, hot sweats, hot flashes, abnormal emotions, headaches, dizziness, palpitations, insomnia and forgetfulness, back pain, abnormal skin sensation, etc. The occurrence of this disease is closely related to the physiological characteristics of women before and after menopause, and is often related to factors such as insufficient endowment, emotional injury, improper work and rest, injury from pregnancy and lactation, and exhaustion of Tiangui. Kidney deficiency is the root cause of the disease. Different symptoms may occur due to deficiency of yin, deficiency of yang, or deficiency of both yin and yang. The disease is located in the kidney, but it often involves multiple organs and meridians such as the heart, liver, and spleen, making the symptoms of this disease complex.

[0003] At present, Western medicine mainly uses hormone replacement therapy for female menopausal syndrome. Although it has a positive effect, it has many contraindications, adverse reactions and side effects, which limit its application to a certain extent. Compared with chemical drugs, Chinese medicine has fewer adverse reactions, fewer side effects and can be taken for a long time; therefore, developing a Chinese medicine composition for treating female menopausal syndrome has important application value. Female menopausal syndrome belongs to the category of "pre-menopausal and post-menopausal syndrome" in traditional Chinese medicine. Traditional Chinese medicine believes that when women reach the age of 77, their Ren meridian is weak, their Taichong meridian is weak, their Tiangui is exhausted, their kidney qi gradually declines, their liver and kidney functions are insufficient, their essence and blood are deficient, and their yin and yang are out of balance, resulting in a series of symptoms related to menopause, including hot sweating, irritability, dizziness and tinnitus, palpitations and insomnia, back pain, facial swelling and limb swelling, and emotional restlessness. Traditional Chinese medicine starts from the overall disease and treats it based on syndrome differentiation, which has obvious advantages. Clinical medications include ancient prescriptions, such as Zuogui Pills, Liuwei Dihuang Pills, Erzhi Pills, Yougui Pills, Erxian Decoction, Xiaoyao Pills, Wumei Pills, Shengmai Powder, Guipi Pills, etc. In addition, there are many self-made prescriptions by modern clinicians. Although these prescriptions have their own characteristics, they are biased towards one corner, with a relatively narrow scope of application and low versatility. Modern women need to bear the pressure and challenges of society, work, family, etc., and their emotions are not smooth, the liver fails to vent, the qi is stagnant, and the depression turns into fire for a long time, which offends the heart, or the wood is depressed and the soil is stagnant, or the depression causes blood stasis for a long time, etc., and then a series of menopausal discomfort symptoms appear. Therefore, it is more important to further develop a Chinese medicine composition for the treatment of female menopausal syndrome that has the characteristics of adapting to the modern background female patient population and has a more comprehensive efficacy. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine composition for treating female menopausal syndrome in view of the deficiencies of the prior art.

[0005] The invention provides a Chinese medicine composition for treating female menopausal syndrome, which is composed of the following raw materials in parts by weight: 4-24 parts of cockscomb, 10-60 parts of kudzu flower, 7-40 parts of sophora japonica, 5-30 parts of snow clam, 4-24 parts of rhodiola rosea, 3-20 parts of cimicifuga, 5-30 parts of chrysanthemum, 4-24 parts of lotus seed heart, and 4-24 parts of cnidium monnieri. The Chinese medicine composition is preferably composed of 8-20 parts of cockscomb, 20-50 parts of kudzu flower, 15-30 parts of sophora japonica, 10-20 parts of snow clam, 8-20 parts of rhodiola rosea, 6-15 parts of cimicifuga, 10-20 parts of chrysanthemum, 8-20 parts of lotus seed heart, and 8-20 parts of cnidium monnieri. The Chinese medicine composition is further preferably composed of: 12 parts of cockscomb, 30 parts of kudzu flower, 20 parts of sophora japonica flower, 15 parts of snow clam, 12 parts of rhodiola rosea, 10 parts of cimicifuga, 15 parts of chrysanthemum, 12 parts of lotus seed core, and 12 parts of cnidium monnieri.

[0006] The present invention also provides a pharmaceutical preparation for treating female menopausal syndrome, which is prepared from the Chinese medicine composition for treating female menopausal syndrome described in any of the previous technical solutions. Preferably, the pharmaceutical preparation is an oral solution, which is prepared according to the following steps:

[0007] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 10-85% ethanol solution and reflux extract 1-3 times, each time for 1-3 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.0-1.3 (45°C);

[0008] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with menthol and sweet liquor, and the mixture is packaged.

[0009] Preferably, 0.1-1.0 parts of menthol and 20-60 parts of sweet liquor are added to the pharmaceutical preparation and mixed evenly.

[0010] In addition, the present invention also provides the use of a Chinese medicine composition or a pharmaceutical preparation for treating female menopausal syndrome as described in any of the previous technical solutions in the preparation of a drug for treating female menopausal syndrome.

[0011] The Chinese medicine composition for treating female menopausal syndrome of the present invention is explained as follows:

[0012] In the Chinese medicine composition for treating female menopausal syndrome of the present invention, cockscomb is cool in nature, sweet and astringent in taste, and has the effects of astringent hemostasis, spleen invigoration and leukorrhea stopping; Sophora japonica is slightly cold in nature, bitter in taste, belongs to the liver meridian, has the effects of cooling blood and hemostasis, clearing away the fire of the heart and liver, and can also relieve skin heat, drain the qi of the lung metal, and relieve the dryness and heat symptoms of menopausal patients; Pueraria lobata has the effects of aromatic invigorating the spleen, strengthening the spleen and stomach, and stopping bleeding; the three are monarch drugs. Snow frog has yin and yang, and has the nature of collection. It is a product with blood and flesh, and has the effects of nourishing the kidney and benefiting essence, strengthening the brain and benefiting intelligence; modern medicine points out that it has the effects of delaying aging, anti-fatigue, and regulating endocrine; Rhodiola rosea has the effects of invigorating qi and clearing the lungs, nourishing lung metal and generating kidney water, replenishing acquired qi, astringent hemostasis, and modern research shows that it has the effects of anti-aging, anti-oxidation, relieving depression and anxiety, and improving sleep; Cimicifuga heracleifolia and Pueraria lobata flower raise yang qi and coordinate qi mechanism; the three are ministerial drugs. Chrysanthemum enters the liver meridian, can clear liver heat, calm liver yang; lotus seed heart has the effect of clearing the heart and eliminating troubles, and connecting the heart and kidney; lotus seed heart has the effect of clearing the heart and eliminating troubles, and connecting the heart and kidney; Cnidium monnieri has the effect of drying dampness, killing insects, relieving itching, warming the kidney and strengthening yang. Modern medical research has found that this drug can be sedative, anti-anxiety, anti-microbial, and similar to sex hormone-like effects; the three are adjuvants. Menthol is aromatic and can refresh the mind, soothe the liver and promote qi; sweet white wine tastes sweet and warm, warms the middle jiao, and helps yang with a small fire; the two are guiding drugs. If the kidney wants to be strong, eat bitter food to strengthen it, use bitter to nourish it, and use salty to purge it. The Chinese medicine composition of the present invention has bitter and cold products as the base, strengthens yin and strengthens the kidney, purges to preserve yin, sweet medicine protects the stomach, and invigorates the yang of the middle jiao to prevent excessive purge, and is combined with pungent medicine to disperse the stagnant heat of the skin, regulate the rise and fall of qi, and all the medicines are used together to play the effects of clearing the heart and eliminating troubles, nourishing yin and tonifying the kidney, and calming and cooling blood.

[0013] Compared with the prior art, the beneficial effects of the present invention include:

[0014] (1) The Chinese medicine composition of the present invention is obtained by the inventor under the guidance of traditional Chinese medicine theory and after years of clinical application summary, and after analysis, research and verification. The present invention overcomes the shortcomings of the prior art, has a scientific and reasonable formula, and has a definite therapeutic effect.

[0015] (2) The present invention adds menthol and sweet liquor to the composition consisting of cockscomb, kudzu flower, sophora flower, snow clam, rhodiola rosea, cimicifuga, chrysanthemum, lotus seed core and cnidium monnieri, which can greatly improve the therapeutic effect of the prepared composition on menopausal syndrome.

[0016] (3) The Chinese medicine composition of the present invention has strong general applicability for treating female menopausal syndrome, is simple in preparation method, is convenient to use, and is suitable for commercial production. DETAILED DESCRIPTION

[0017] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0018] Example 1

[0019] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 24 parts of cockscomb flowers, 60 parts of kudzu flowers, 40 parts of sophora japonica flowers, 30 parts of snow clam, 24 parts of rhodiola rosea, 20 parts of cimicifuga, 30 parts of chrysanthemum, 24 parts of lotus seed core, and 24 parts of cnidium monnieri.

[0020] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0021] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 85% ethanol solution for reflux extraction 3 times, each time for 2 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.3 (45°C);

[0022] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 1.0 part of menthol and 60 parts of sweet liquor, and the mixture is packaged.

[0023] Example 2

[0024] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 20 parts of cockscomb flowers, 50 parts of kudzu flowers, 30 parts of sophora japonica flowers, 20 parts of snow clam, 20 parts of rhodiola rosea, 15 parts of cimicifuga, 20 parts of chrysanthemum, 20 parts of lotus seed core, and 20 parts of cnidium monnieri.

[0025] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0026] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 40% ethanol solution and reflux extract twice, each time for 3 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.3 (45°C);

[0027] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 0.8 parts of menthol and 50 parts of sweet liquor, and the mixture is packaged.

[0028] Example 3

[0029] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 12 parts of cockscomb flowers, 30 parts of kudzu flowers, 20 parts of sophora japonica flowers, 15 parts of snow clam, 12 parts of rhodiola rosea, 10 parts of cimicifuga, 15 parts of chrysanthemum, 12 parts of lotus seed core, and 12 parts of cnidium monnieri.

[0030] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0031] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 60% ethanol solution and reflux extract twice, each time for 1 hour, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.2 (45°C);

[0032] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 0.5 parts of menthol and 40 parts of sweet liquor, and the mixture is packaged.

[0033] Example 4

[0034] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 8 parts of cockscomb flowers, 10 parts of kudzu flowers, 7 parts of sophora japonica flowers, 5 parts of snow clam, 4 parts of rhodiola rosea, 3 parts of cimicifuga, 10 parts of chrysanthemum, 8 parts of lotus seed core, and 4 parts of cnidium monnieri.

[0035] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0036] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 60% ethanol solution for reflux extraction once, each time for 3 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.0 (45°C);

[0037] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 0.1 part of menthol and 20 parts of sweet liquor, and the mixture is packaged.

[0038] Example 5

[0039] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 4 parts of cockscomb flowers, 40 parts of kudzu flowers, 30 parts of sophora japonica flowers, 25 parts of snow clam, 24 parts of rhodiola rosea, 10 parts of cimicifuga, 5 parts of chrysanthemum, 4 parts of lotus seed core, and 15 parts of cnidium monnieri.

[0040] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0041] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 60% ethanol solution and reflux extract twice, each time for 2 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.2 (45°C);

[0042] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 0.3 parts of menthol and 40 parts of sweet liquor, and the mixture is packaged.

[0043] Example 6

[0044] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 10 parts of cockscomb flowers, 45 parts of kudzu flowers, 30 parts of sophora japonica flowers, 25 parts of snow clam, 10 parts of rhodiola rosea, 12 parts of cimicifuga heracleifolia, 25 parts of chrysanthemum, 15 parts of lotus seed core, and 20 parts of cnidium monnieri.

[0045] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0046] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 50% ethanol solution and reflux extract for 3 times, each time for 1 hour, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.01 (45°C);

[0047] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 0.5 parts of menthol and 40 parts of sweet liquor, and the mixture is packaged.

[0048] Example 7

[0049] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 24 parts of cockscomb flowers, 60 parts of kudzu flowers, 40 parts of sophora japonica flowers, 30 parts of snow clam, 24 parts of rhodiola rosea, 20 parts of cimicifuga, 30 parts of chrysanthemum, 24 parts of lotus seed core, and 24 parts of cnidium monnieri.

[0050] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0051] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 10% ethanol solution and reflux extract for 3 times, each time for 2 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.1 (45°C);

[0052] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 1.0 part of menthol and packaged.

[0053] Example 8

[0054] A traditional Chinese medicine composition for treating female menopausal syndrome is prepared from the following raw materials in parts by weight: 24 parts of cockscomb flowers, 60 parts of kudzu flowers, 40 parts of sophora japonica flowers, 30 parts of snow clam, 24 parts of rhodiola rosea, 20 parts of cimicifuga, 30 parts of chrysanthemum, 24 parts of lotus seed core, and 24 parts of cnidium monnieri.

[0055] The preparation method of the above-mentioned pharmaceutical preparation for treating female menopausal syndrome comprises the following steps:

[0056] (1) Preparation of a pharmaceutical preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 85% ethanol solution and reflux extract twice, each time for 3 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.1 (45°C);

[0057] (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 60 parts of sweet liquor and packaged.

[0058] Example 9

[0059] 90 adult non-pregnant female SD rats weighing 200±20g were selected. After anesthesia, the abdominal cavity was opened and the bilateral ova were removed.

[0060] The ovaries were removed and the abdominal cavity was sutured, and then antibiotics were injected for 5 consecutive days to prevent infection; followed by feeding for 2 weeks to construct a female rat model of menopausal syndrome.

[0061] In addition, 10 adult non-pregnant female SD rats weighing 200±20g were anesthetized and opened the abdominal cavity without removing the bilateral ovaries. The abdominal cavity was then sutured and antibiotics were injected for 5 consecutive days for anti-infection. The rats were then fed in the same way for 2 weeks as a sham operation control group.

[0062] Female rats with menopausal syndrome model were randomly divided into 9 groups. One group was the model group, and the other 8 groups were experimental groups. The experimental groups were respectively gavaged with the Chinese medicine composition prepared in Examples 1 to 8 at a dose of 1.0 g / kg per day. The model group and the sham operation control group were gavaged with an equal amount of distilled water every day. After continuous administration for 4 weeks, blood was collected from the abdominal aorta, and the contents of E2, LH and FSH in the plasma of each SD rat were determined according to the method in the kit instructions; the test results are shown in Table 1.

[0063] The E2 content in the plasma of female rats with menopausal syndrome model will decrease, while the LH and FSH levels will increase.

[0064]

[0065] From the experimental data in Table 1, it can be seen that compared with the model group and the sham operation control group, the E2 in the SD rats in the model group was significantly reduced, and the content of LH and FSH was significantly increased; this shows that the menopausal syndrome model of female rats was successfully constructed.

[0066] As can be seen from the experimental data in Table 1, after the SD rats in the experimental groups 1 to 8 were gavaged with the Chinese medicine compositions of Examples 1 to 8, compared with the SD rats in the model group, the content of E2 was significantly increased, and the content of LH and FSH was significantly reduced. This shows that the Chinese medicine composition prepared with nine herbs such as cockscomb, kudzu flower, sophora japonica, snow clam, rhodiola rosea, cimicifuga, chrysanthemum, lotus heart, and cnidium monnieri has the effect of treating menopausal syndrome. And compared with experimental groups 7 to 8, the content of E2 in experimental groups 1 to 6 was more significantly increased, and the content of LH and FSH was more significantly reduced. This shows that on the basis of the prescription of cockscomb, kudzu flower, sophora japonica, snow clam, rhodiola rosea, cimicifuga, chrysanthemum, lotus heart, and cnidium monnieri, menthol and sweet liquor were added, which has a very excellent therapeutic effect on female menopausal syndrome.

[0067] Example 10

[0068] The Chinese medicine composition for treating female menopausal syndrome of the present invention is a clinical prescription of traditional Chinese medicine, which has been clinically used for many years and has good clinical efficacy. The specific clinical effects are as follows:

[0069] 100 patients with female menopausal syndrome were selected as research subjects and divided into a control group (n=50) and a research group (n=50) according to the random number table method. The control group was treated with progesterone, and the research group took the oral solution for treating female menopausal syndrome prepared in Example 3; 3 times a day, 1 bottle each time, and the efficacy was evaluated after continuous treatment for 2 months, and the observation indicators such as Kuppermann symptom scores and adverse drug reactions of the two groups of patients were compared. According to the general efficacy standard of Kuppermarm symptom scores, among the 50 patients in the research group, there were 0 cases of complete remission, 36 cases of effective, 5 cases of marked effect, and the clinical remission rate (complete remission + marked effect + effective) reached 90%. While there were 0 cases of complete remission, 0 cases of effective, 0 cases of marked effect in the control group, and the clinical remission rate (complete remission + marked effect + effective) was 0% (P<0.05). The symptom scores of the research group were compared before and after treatment, and there was a significant difference after statistical processing (P<0.01); the symptom scores of the control group did not improve significantly (P>0.05). The difference in symptom scores between the two groups before and after treatment was statistically analyzed and showed significant difference (P<0.01), indicating that the therapeutic effect of the study group was better than that of the control group.

[0070]

[0071]

[0072] The above-mentioned specific implementation of the present invention does not constitute a limitation on the protection scope of the present invention. Any other corresponding changes and modifications made according to the technical concept of the present invention should be included in the protection scope of the claims of the present invention.

Claims

1. A Chinese medicine composition for treating female menopausal syndrome, characterized in that: The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 4-24 parts of cockscomb flowers, 10-60 parts of kudzu flowers, 7-40 parts of sophora japonica flowers, 5-30 parts of snow clam, 4-24 parts of rhodiola rosea, 3-20 parts of cimicifuga, 5-30 parts of chrysanthemum, 4-24 parts of lotus seed core and 4-24 parts of cnidium monnieri.

2. A Chinese medicine composition for treating female menopausal syndrome according to claim 1, characterized in that: The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 8-20 parts of cockscomb flowers, 20-50 parts of kudzu flowers, 15-30 parts of sophora japonica flowers, 10-20 parts of snow clam, 8-20 parts of rhodiola rosea, 6-15 parts of cimicifuga, 10-20 parts of chrysanthemum, 8-20 parts of lotus seed core and 8-20 parts of cnidium monnieri.

3. A Chinese medicine composition for treating female menopausal syndrome according to claim 1, characterized in that: The Chinese medicine composition is composed of the following raw materials in parts by weight: 12 parts of cockscomb flowers, 30 parts of kudzu flowers, 20 parts of sophora japonica flowers, 15 parts of snow clam, 12 parts of rhodiola rosea, 10 parts of cimicifuga, 15 parts of chrysanthemum, 12 parts of lotus seed core and 12 parts of cnidium monnieri.

4. A Chinese medicine composition for treating female menopausal syndrome according to any one of claims 1 to 3, characterized in that: The Chinese medicine composition is prepared into an oral solution.

5. A Chinese medicine composition for treating female menopausal syndrome according to claim 4, characterized in that: The oral solution is prepared according to the following steps: (1) Preparation of a drug preparation for treating menopausal syndrome in women: Weigh cockscomb, kudzu flower, sophora japonica flower, snow clam, rhodiola rosea, cimicifuga heracleifolia, chrysanthemum, lotus seed core, and cnidium monnieri by weight, add 10-85% ethanol solution and reflux extract 1-3 times, each time for 1-3 hours, filter, combine the filtrate, and concentrate under reduced pressure to an extract with a relative density of 1.0-1.3 (45°C); (2) Preparation of preparation: The drug obtained in step (1) is mixed evenly with 0.1-1.0 parts of menthol and 20-60 parts of sweet liquor, and the mixture is packaged.

6. Use of a Chinese medicine composition for treating female menopausal syndrome as described in any one of claims 1 to 5 in the preparation of a medicament for treating female menopausal syndrome.

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