Traditional Chinese medicine composition for external treatment of children adenoid hypertrophy and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine external treatment medicine composition for treating children adenoid hypertrophy and a preparation method thereof. The traditional Chinese medicine external treatment medicine composition is prepared from the following components in parts by weight: 6 parts of flos magnoliae, 6 parts of rhizoma curcumae, 6 parts of rhizoma sparganii, 6 parts of rhizoma chuanxiong, 8 parts of radix cynanchi paniculati, 8 parts of bulbus fritillariae thunbergii, 8 parts of spica prunellae, 3 parts of raw herba ephedrae, 3 parts of herba asari and 3 parts of rhizoma cimicifugae. The traditional Chinese medicine is applied to acupuncture points such as Tianji, Dazhui and Shenque in a traditional Chinese medicine external treatment mode, effects are achieved through acupuncture point stimulation and medicine percutaneous absorption, the problems that children are difficult to orally take medicines and possibly stimulate gastrointestinal tracts and the like are avoided, operation is relatively simple and convenient, implementation is easy, the acceptability of child patients is relatively high, and the traditional Chinese medicine is worthy of popularization and application. The system is convenient to use at home and the like, and reduces the medical cost and burden to a certain extent.

Description

Technical Field

[0001] The invention relates to the field of medicine, and in particular to a traditional Chinese medicine external treatment drug combination for treating children's adenoids hypertrophy and a preparation method thereof. Background Art

[0002] Adenoids, also known as pharyngeal tonsils or adenoids, are located at the junction of the top and back walls of the nasopharynx, between the pharyngeal recesses on both sides, and are part of the pharyngeal lymphatic ring. They have dual humoral and cellular immune functions, protecting the upper respiratory tract from pathogens. Adenoids exist at birth, gradually increase in size between the ages of 2 and 7, are most significant between the ages of 6 and 7, and gradually shrink after the age of 10. Adenoids hypertrophy is a common clinical disease in pediatrics, with the main manifestations being nasal congestion, snoring, bad breath, mouth breathing, adenoid facies, etc. The incidence rate is 2% to 3%, of which the incidence rate of symptomatic children is as high as 34.46%, often accompanied by sinusitis, secretory otitis media, and cognitive dysfunction. At the same time, it is considered to be an important independent risk factor for obstructive sleep apnea syndrome in children, which seriously endangers the physical and mental health of children and creates a burden on families and society.

[0003] At present, adenoidectomy is the main treatment method, but there are problems such as damage to the local immune function of the nasopharynx of children, postoperative complications and surgical anesthesia risks, which make some parents of children afraid of surgery; there is no specific drug for the treatment of adenoids hypertrophy in children at home and abroad, and most of them are symptomatic supportive treatment, and there are problems such as long treatment cycle and poor effect. Traditional Chinese medicine has accumulated rich experience in regulating adenoids hypertrophy in children, with definite efficacy, high safety, few adverse reactions and short treatment cycle, but there is no Chinese patent medicine for the treatment of adenoids hypertrophy in children in clinical use in the Chinese market; therefore, the present invention provides a combination of traditional Chinese medicine for external treatment of adenoids hypertrophy in children and a method for preparing the prepared patch to solve the above technical problems. Summary of the invention

[0004] In view of the problem that there is no Chinese patent medicine for treating children's adenoids hypertrophy in clinical use in the current Chinese market, the present invention is proposed.

[0005] Therefore, the purpose of the present invention is to provide a combination of traditional Chinese medicine for external treatment of adenoids hypertrophy in children and a preparation method, which has no side effects and has a strong effect, fills the gap in high-efficiency traditional Chinese medicine acupoint external application specifically for the treatment of adenoids hypertrophy, and avoids the mental and organ damage to children caused by modern medical surgical cutting; it can restore adenoids hypertrophy to a normal size range and effectively control the development of adenoids hypertrophy.

[0006] In order to achieve the above object, the present invention provides the following technical solutions:

[0007] A traditional Chinese medicine external treatment drug combination for treating adenoids hypertrophy in children is composed of the following components in parts by weight: 5-8 parts of magnolia, 5-8 parts of curcuma, 5-8 parts of trillium, 5-8 parts of ligusticum chuanxiong, 6-10 parts of cynanchum, 6-10 parts of fritillaria thunbergii, 6-10 parts of prunella vulgaris, 2-4 parts of raw ephedra, 5-8 parts of asarum, 5-8 parts of cimicifuga, and 3-5 parts of borneol.

[0008] Preferably, it is composed of the following components in parts by weight: 6 parts of magnolia, 6 parts of curcuma, 6 parts of trigonosciadium japonicum, 6 parts of ligusticum chuanxiong, 8 parts of cynanchum wilfordii, 8 parts of fritillaria thunbergii, 8 parts of selfheal, 3 parts of raw ephedra, 3 parts of asarum, and 3 parts of cimicifuga.

[0009] The preparation method of a combination of traditional Chinese medicine for treating adenoids hypertrophy in children comprises the following steps: pulverizing magnolia, zedoaria, trillium, ligusticum chuanxiong, cynanchum chinense, fritillaria thunbergii, herba prunellae, raw ephedra, asarum and cimicifuga in corresponding weight proportions respectively, and using a small-scale Chinese herbal medicine ultrafine pulverizer to grind them into 100-200 mesh powders for extraction respectively.

[0010] Preferably, the patch is prepared by molding with vaseline:

[0011] Step 1, adding 400-500 parts of vaseline ointment into 40-50 parts of lanolin, heating and stirring, then gradually adding the crushed and ground Chinese medicine fine powder into the blended Chinese medicine ointment, stirring evenly while adding;

[0012] Step 2: During the stirring process, ensure that the Chinese medicine powder and vaseline are fully mixed to form a uniform paste;

[0013] Step three, prepare a disposable sterile acupoint treatment patch, ensure that its quality meets medical standards, take an appropriate amount of the drug mixture formed with vaseline and place it in the center of the acupoint treatment patch, ensuring that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupoint.

[0014] Preferably, the dressing is prepared by mixing with excipient fresh ginger juice:

[0015] Step 1, weighing corresponding weight portions of fresh ginger, crushing it, and mechanically squeezing ginger juice at 0-2°C;

[0016] Step 2, mixing the ginger juice obtained in the first step with the fine powder of the crushed Chinese medicine, heating and stirring until the temperature reaches 50-55° C., to obtain the main drug;

[0017] Step three, prepare a disposable sterile acupoint patch, ensure that its quality meets medical standards, take an appropriate amount of the drug mixture formed with fresh ginger juice and place it in the center of the acupoint patch, ensuring that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupoint.

[0018] The method for using the patch prepared by the patch preparation method is to stick the acupoint patch with medicine on acupoints such as Tiantu, Dazhui, Shenque, etc. to exert its therapeutic effect.

[0019] In the above technical solution, the technical effects and advantages provided by the present invention are:

[0020] Since the current adenoidectomy has the problems of damaging the local immune function of the nasopharynx of children, postoperative complications and surgical anesthesia risks, and Chinese medicine itself has few adverse reactions, the Chinese medicine external treatment drug combination and patch of the present invention are based on Chinese medicine theory and are made of natural Chinese medicinal materials, avoiding many risks brought by surgery and possible side effects of modern drugs, being more friendly to children's bodies, allowing parents to choose with confidence and reducing potential adverse effects on children's health.

[0021] The prepared Chinese medicine patch of the present invention fills the blank of the high-efficiency Chinese medicine acupoint external application patch specially used for treating adenoids hypertrophy in children. Aiming at adenoids hypertrophy, a common clinical disease in pediatrics, the selected Chinese medicines such as magnolia, curcuma, three-edged sword, chuanxiong and the like are compatible with each other and can play a synergistic role, so that the adenoids hypertrophy can be restored to a normal size range, the development of adenoids hypertrophy can be effectively controlled, and the main manifestation symptoms of adenoids hypertrophy such as nasal congestion, snoring, bad breath, mouth breathing, adenoids face and the like can be improved, which is helpful to improve the quality of life of children with the disease.

[0022] The present invention adopts the TCM external treatment method of applying a patch to stick the medicine on acupuncture points such as Tiantu, Dazhui, Shenque, etc., and exerts its effects through acupuncture point stimulation and percutaneous absorption of the medicine, thereby avoiding the difficulty of children taking oral medicines and possible irritation to the gastrointestinal tract, etc., and the operation is relatively simple and easy to implement, the acceptance degree of children is relatively high, and it is convenient to use in places such as homes, thereby reducing the cost and burden of medical treatment to a certain extent. DETAILED DESCRIPTION

[0023] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention is further described in detail below.

[0024] Example 1

[0025] The embodiment of the present invention discloses a combination of traditional Chinese medicine for external treatment of adenoid hypertrophy in children and a preparation method thereof.

[0026] A traditional Chinese medicine external treatment drug combination for treating adenoids hypertrophy in children is composed of the following components in parts by weight: 5-8 parts of magnolia, 5-8 parts of curcuma, 5-8 parts of trillium, 5-8 parts of ligusticum chuanxiong, 6-10 parts of cynanchum, 6-10 parts of fritillaria thunbergii, 6-10 parts of prunella vulgaris, 2-4 parts of raw ephedra, 5-8 parts of asarum, and 5-8 parts of cimicifuga.

[0027] The invention is composed of the following components in parts by weight: 6 parts of magnolia, 6 parts of zedoaria, 6 parts of trillium, 6 parts of ligusticum chuanxiong, 8 parts of cynanchum, 8 parts of fritillaria thunbergii, 8 parts of prunella vulgaris, 3 parts of raw ephedra, 3 parts of asarum, 3 parts of cimicifuga, and 4 parts of borneol.

[0028] The preparation method of a combination of traditional Chinese medicine for external treatment of adenoids hypertrophy in children comprises the following steps: pulverizing magnolia, zedoaria, trillium, ligusticum chuanxiong, cynanchum chinense, fritillaria thunbergii, herba prunellae, raw ephedra, asarum and cimicifuga in corresponding weight proportions respectively, and using a small-scale Chinese herbal medicine ultrafine pulverizer to grind the powder into 150 mesh powder for extraction respectively.

[0029] Preparation method of dressing: molding with vaseline:

[0030] Step 1: Add 400-500 parts of Vaseline ointment into 40-50 parts of lanolin, heat and stir, then gradually add the crushed Chinese medicine fine powder into the blended Chinese medicine ointment, stirring evenly while adding.

[0031] Step 2: Continue stirring to ensure that the Chinese medicine powder and vaseline are fully mixed to form a uniform paste.

[0032] Step 3: Prepare a disposable sterile acupuncture point patch and ensure that its quality meets medical standards. Place an appropriate amount of the drug mixture formed with vaseline in the center of the acupuncture point patch. Make sure that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupuncture point.

[0033] Preparation method 2 of the patch: Mix with excipient fresh ginger juice:

[0034] Step 1: Take the corresponding amount of fresh ginger by weight, crush it, and mechanically squeeze the ginger juice at 1°C.

[0035] Step 2: Mix the squeezed ginger juice with the crushed Chinese medicine fine powder, and heat and stir until the temperature reaches 54°C to obtain the main medicine.

[0036] Step 3: Prepare a disposable sterile acupuncture point patch and ensure that its quality meets medical standards; take an appropriate amount of the drug mixture formed with fresh ginger juice and place it in the center of the acupuncture point patch to ensure that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupuncture point.

[0037] How to use the patch: Apply the acupoint patch with medicine on the Tiantu, Dazhui, Shenque and other acupoints to exert its effect in treating adenoids hypertrophy in children.

[0038] Example 2

[0039] A traditional Chinese medicine external treatment drug combination for treating adenoids hypertrophy in children is composed of the following components in parts by weight: 6 parts of magnolia, 6 parts of curcuma, 6 parts of trillium, 6 parts of ligusticum chuanxiong, 8 parts of cynanchum, 8 parts of fritillaria thunbergii, 8 parts of prunella vulgaris, 3 parts of raw ephedra, 3 parts of asarum, 3 parts of cimicifuga, and 4 parts of borneol.

[0040] A method for preparing a patch of a combination of traditional Chinese medicine for treating adenoids hypertrophy in children comprises the following steps: crushing magnolia, curcuma, trillium, ligusticum chuanxiong, cynanchum chinense, fritillaria thunbergii, herba prunellae, raw ephedra, asarum and cimicifuga in corresponding weight portions respectively, and using a small-scale Chinese herbal medicine ultrafine grinding unit to grind the powder into 150 mesh powder for extraction respectively.

[0041] Molding with Vaseline:

[0042] Step 1: Add 500 parts of Vaseline ointment into 50 parts of lanolin and heat and stir. Then gradually add the crushed Chinese medicine fine powder into the blended Chinese medicine ointment, stirring evenly while adding.

[0043] Step 2: Continue stirring to ensure that the Chinese medicine powder and vaseline are fully mixed to form a uniform paste.

[0044] Step 3: Prepare a disposable sterile acupuncture point patch and ensure that its quality meets medical standards. Place an appropriate amount of the drug mixture formed with vaseline in the center of the acupuncture point patch. Make sure that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupuncture point.

[0045] Apply the medicated acupuncture patches on the Tiantu, Dazhui, Shenque and other acupuncture points to exert its effect in treating adenoids hypertrophy in children.

[0046] The clinical treatment data are as follows:

[0047]

[0048] The clinical symptom scoring criteria are as follows:

[0049]

[0050]

[0051] According to the table above, applying the Chinese medicine formula patch on the corresponding acupoints on time can restore the adenoids to a normal size, effectively control the development of adenoids, and improve the main symptoms of adenoids hypertrophy such as nasal congestion, snoring, and open-mouth breathing, thereby improving the quality of life of children with adenoids.

[0052] It should be understood that the embodiments of the present application are not limited to the precise structures described and shown above, and various modifications and changes can be made without departing from the scope thereof. The scope of the embodiments of the present application is limited only by the appended claims.

[0053] The above-mentioned embodiments only express several implementation methods of the embodiments of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the embodiments of the present application, and these all belong to the protection scope of the embodiments of the present application.

Claims

1. A Chinese medicine external treatment drug combination for treating adenoids hypertrophy in children, characterized in that: The invention is composed of the following components in parts by weight: 5-8 parts of magnolia flower, 5-8 parts of zedoaria, 5-8 parts of trillium, 5-8 parts of ligusticum chuanxiong, 6-10 parts of cynanchum, 6-10 parts of fritillaria thunbergii, 6-10 parts of prunella vulgaris, 2-4 parts of raw ephedra, 5-8 parts of asarum, 5-8 parts of cimicifuga and 3-5 parts of borneol.

2. The Chinese medicine external treatment drug combination for treating adenoids hypertrophy in children according to claim 1, characterized in that: The invention is composed of the following components in parts by weight: 6 parts of magnolia, 6 parts of zedoaria, 6 parts of trillium, 6 parts of ligusticum, 6 parts of chuanxiong, 8 parts of cynanchum, 8 parts of fritillaria thunbergii, 8 parts of prunella vulgaris, 3 parts of raw ephedra, 3 parts of asarum and 3 parts of cimicifuga.

3. The method for preparing the Chinese medicine combination for treating adenoids hypertrophy in children according to any one of claims 1 to 2, characterized in that: Corresponding weight portions of magnolia, zedoaria, trillium, ligusticum chuanxiong, cynanchum chinense, thunbergii bulb, herba prunellae, raw ephedra, asarum and cimicifuga are crushed separately and grinded into 100-200 mesh medicinal powders by a small-scale Chinese herbal medicine ultrafine grinding unit for extraction.

4. The method for preparing a patch according to claim 3, characterized in that: Molding with Vaseline: Step 1, adding 400-500 parts of vaseline ointment into 40-50 parts of lanolin, heating and stirring, then gradually adding the crushed and ground Chinese medicine fine powder into the blended Chinese medicine ointment, stirring evenly while adding; Step 2: During the stirring process, ensure that the Chinese medicine powder and vaseline are fully mixed to form a uniform paste; Step three, prepare a disposable sterile acupoint treatment patch, ensure that its quality meets medical standards, take an appropriate amount of the drug mixture formed with vaseline and place it in the center of the acupoint treatment patch, ensuring that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupoint.

5. The method for preparing a patch according to claim 3, characterized in that: Mix with excipient fresh ginger juice: Step 1, weighing corresponding weight portions of fresh ginger, crushing it, and mechanically squeezing ginger juice at 0-2°C; Step 2, mixing the ginger juice obtained in the first step with the fine powder of the crushed Chinese medicine, heating and stirring until the temperature reaches 50-55° C., to obtain the main drug; Step three, prepare a disposable sterile acupoint patch, ensure that its quality meets medical standards, take an appropriate amount of the drug mixture formed with fresh ginger juice and place it in the center of the acupoint patch, ensuring that the drug is evenly distributed and has a moderate thickness so that it can better fit the acupoint.

6. A method for using a patch prepared by the method for preparing a patch according to any one of claims 4 to 5, characterized in that: Apply the medicated acupoint patch on the Tiantu, Dazhui, Shenque and other acupoints to exert its therapeutic effect.

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