A peptide-containing composition capable of improving qi and blood function, and its preparation method and application

Abstract

The present invention belongs to the technical field of functional foods, and specifically relates to a peptide-containing composition with the function of improving qi and blood, and its preparation method and application. The peptide-containing composition of the present invention includes: ginseng oligopeptides, donkey-hide gelatin peptides, bovine blood peptides, wolfberry peptides, fish collagen peptides, American ginseng peptides, lily extracts, licorice extracts, sea buckthorn fruit powder, polydextrose and xanthan gum. The peptide-containing composition innovatively uses a variety of small molecule active peptides as core ingredients, and is combined with synergistic plant extracts, dietary fiber and fruit powder; it not only has advantages in the absorption and utilization of ingredients, but also is more comprehensive and in-depth in the effects and mechanisms of action of improving qi and blood. Through the synergistic effect of multiple peptide ingredients, it can promote the generation of qi and blood and regulate the circulation of qi and blood from multiple levels, while enhancing the body's immunity and antioxidant capacity, providing a more effective solution for improving qi and blood.

Description

Technical Field

[0001] The present invention belongs to the technical field of functional foods, and in particular relates to a peptide-containing composition capable of improving qi and blood functions, and a preparation method and application thereof. Background Art

[0002] Qi and blood, crucial concepts in Traditional Chinese Medicine, are the material foundation for maintaining normal bodily function. Qi has the functions of promoting, warming, defending, consolidating, and transforming qi, while blood nourishes and moisturizes the entire body. Qi promotes blood circulation, while blood transports qi, mutually reinforcing each other. Only when qi and blood are sufficient and flowing smoothly can the human body maintain a healthy state. Conversely, insufficient or malfunctioning qi and blood can lead to a variety of illnesses, such as pale complexion, dizziness, palpitations, insomnia, fatigue, and other serious side effects, seriously affecting people's quality of life and physical health.

[0003] The main causes of Qi and blood deficiency are as follows: Qi deficiency can be caused by dysfunctional lung qi management, dysfunctional spleen and stomach transport and transformation, and decreased kidney qi intake, leading to insufficient Qi production. Excessive fatigue and chronic illness can lead to excessive Qi depletion. Blood deficiency can also be caused by spleen and stomach weakness, which can lead to insufficient blood production, kidney essence deficiency, which can lead to decreased bone marrow hematopoietic function, and insufficient lung qi, which can affect blood distribution. Blood loss and blood stasis can lead to excessive blood consumption or loss, hindering new blood production and further depleting Qi and blood. Anemia can also be caused by a lack of iron, essential for blood production, and the various proteins, carbohydrates, and vitamins that support blood production.

[0004] Current functional foods for replenishing qi and blood are mostly single-function and have limited absorption. For example, patent CN118947913A provides an iron-rich composition with the function of replenishing qi and blood and its preparation method, comprising the following raw materials in parts by weight: 0.05-0.1 parts of ferrous fumarate, 15-20 parts of hemoglobin polypeptide, 1-3 parts of ferrous gluconate, 8-13 parts of soybean polysaccharide, 25-30 parts of xylitol, 5-12 parts of red ginseng extract, 8-13 parts of polygonatum powder, 2-29 parts of wolfberry powder, 0.3-1 parts of acerola cherry powder, 0.1-1 parts of lotus seed powder, and 0.3-2 parts of fish maw oligopeptide. This composition can improve iron absorption and promote the formation of red blood cells and hemoglobin, synergistically improving the blood-tonifying effect. However, the ferrous fumarate and ferrous gluconate therein are easily affected by tannic acid, carbonate, cellulose and oxidizing substances in food, resulting in limited absorption. Patent CN110420313A provides a donkey-hide gelatin and ginseng drink with the function of replenishing qi and blood. Its ingredients include: donkey-hide gelatin, red ginseng, American ginseng, northern astragalus, angelica, Cistanche deserticola, polygonatum, northern schisandra, cinnamon twig, raw rehmannia root, longan pulp, licorice, red dates, honey, fish scale collagen powder, sodium cyclamate, and sterilized water. However, this formula contains as many as 17 ingredients, which may increase the risk of adverse reactions between them. It also lacks clear targeting, making it difficult to highlight the product's specific benefits.

[0005] Therefore, with a variety of small molecule active peptides as the core ingredients, combined with synergistic plant extracts, dietary fiber and fruit powder, we provide a peptide-containing composition that not only has advantages in the absorption and utilization of ingredients, but also is more comprehensive and in-depth in the effects and mechanisms of improving qi and blood. Through the synergistic effect of multiple peptide ingredients, it promotes the generation of qi and blood, regulates the circulation of qi and blood from multiple levels, and at the same time enhances the body's immunity and antioxidant capacity, which can provide a more effective solution for improving qi and blood. Summary of the Invention

[0006] In response to the above-mentioned deficiencies, the present invention provides a peptide-containing composition with the function of improving qi and blood, as well as its preparation method and application. The peptide-containing composition of the present invention includes: ginseng oligopeptides, donkey-hide gelatin peptides, bovine blood peptides, wolfberry peptides, fish collagen peptides, American ginseng peptides, lily extracts, licorice extracts, sea buckthorn fruit powder, polydextrose and xanthan gum. The peptide-containing composition innovatively uses a variety of small molecule active peptides as core ingredients, and is combined with synergistic plant extracts, dietary fiber and fruit powder; it not only has advantages in the absorption and utilization of ingredients, but is also more comprehensive and in-depth in the effects and mechanisms of action of improving qi and blood. Through the synergistic effect of multiple peptide ingredients, it can promote the generation of qi and blood and regulate the circulation of qi and blood from multiple levels, while enhancing the body's immunity and antioxidant capacity, providing a more effective solution for improving qi and blood.

[0007] The technical solution of the present invention is:

[0008] On the one hand, the present invention provides a peptide-containing composition with the function of improving qi and blood, wherein the peptide-containing composition includes ginseng oligopeptide, donkey-hide gelatin peptide, bovine blood peptide, wolfberry peptide, fish collagen peptide, American ginseng peptide, lily extract, licorice extract, sea buckthorn fruit powder, polydextrose and xanthan gum.

[0009] Specifically, the peptide-containing composition comprises, by weight: 10-25 parts of ginseng oligopeptides, 15-30 parts of donkey-hide gelatin peptides, 8-18 parts of bovine blood peptides, 10-20 parts of wolfberry peptides, 8-15 parts of fish collagen peptides, 5-12 parts of American ginseng peptides, 3-8 parts of lily extracts, 1-5 parts of licorice extracts, 5-12 parts of sea buckthorn fruit powder, 3-10 parts of polydextrose and 1-5 parts of xanthan gum.

[0010] Preferably, the peptide-containing composition comprises, by weight, 10-11 parts, 11-12 parts, 12-13 parts, 13-14 parts, 14-15 parts, 15-16 parts, 16-17 parts, 17-18 parts, 18-19 parts, 19-20 parts, 20-21 parts, 21-22 parts, 22-23 parts, 23-24 parts or 24-25 parts of ginseng oligopeptides.

[0011] Further preferably, the peptide-containing composition comprises, by weight, 12-13 parts, 13-14 parts, 14-15 parts, 15-16 parts, 16-17 parts or 17-18 parts of ginseng oligopeptides.

[0012] Still further preferably, the peptide-containing composition comprises, by weight: 15 parts of ginseng oligopeptides.

[0013] Preferably, the peptide-containing composition comprises, by weight, 15-16 parts, 16-17 parts, 17-18 parts, 18-19 parts, 19-20 parts, 20-21 parts, 21-22 parts, 22-23 parts, 23-24 parts, 24-25 parts, 25-26 parts, 26-27 parts, 27-28 parts, 28-29 parts or 29-30 parts of donkey-hide gelatin peptide.

[0014] Further preferably, the peptide-containing composition comprises, by weight, 18-19 parts, 19-20 parts, 20-21 parts, 21-22 parts, 22-23 parts, 23-24 parts or 24-25 parts of donkey-hide gelatin peptide.

[0015] Still more preferably, the peptide-containing composition comprises, by weight: 20 parts of donkey-hide gelatin peptide.

[0016] Preferably, the peptide-containing composition comprises, by weight, 8-9 parts, 9-10 parts, 10-11 parts, 11-12 parts, 12-13 parts, 13-14 parts, 14-15 parts, 15-16 parts, 16-17 parts or 17-18 parts of bovine blood peptide.

[0017] Further preferably, the peptide-containing composition comprises, by weight, 10-11 parts, 11-12 parts, 12-13 parts, 13-14 parts or 14-15 parts of bovine blood peptide.

[0018] Still further preferably, the peptide-containing composition comprises, by weight, 12 parts of bovine blood peptide.

[0019] Preferably, the peptide-containing composition comprises, by weight, 10-11 parts, 11-12 parts, 12-13 parts, 13-14 parts, 14-15 parts, 15-16 parts, 16-17 parts, 17-18 parts, 18-19 parts or 19-20 parts of wolfberry peptides.

[0020] Further preferably, the peptide-containing composition comprises, by weight, 12-13 parts, 13-14 parts, 14-15 parts or 15-16 parts of wolfberry peptides.

[0021] Still further preferably, the peptide-containing composition comprises, by weight: 15 parts of wolfberry peptides.

[0022] Preferably, the peptide-containing composition comprises, by weight, 8-9 parts, 9-10 parts, 10-11 parts, 11-12 parts, 12-13 parts, 13-14 parts or 14-15 parts of fish collagen peptides.

[0023] Further preferably, the peptide-containing composition comprises, by weight, 9-10 parts, 10-11 parts or 11-12 parts of fish collagen peptides.

[0024] Still further preferably, the peptide-containing composition comprises, by weight: 10 parts of fish collagen peptide.

[0025] Preferably, the peptide-containing composition comprises, by weight, 5-6 parts, 6-7 parts, 7-8 parts, 8-9 parts, 9-10 parts, 10-11 parts or 11-12 parts of American ginseng peptide.

[0026] Further preferably, the peptide-containing composition comprises, by weight, 6-7 parts, 7-8 parts, 8-9 parts or 9-10 parts of American ginseng peptide.

[0027] Still further preferably, the peptide-containing composition comprises, by weight, 8 parts of American ginseng peptide.

[0028] Preferably, the peptide-containing composition comprises, by weight, 3-4 parts, 4-5 parts, 5-6 parts, 6-7 parts or 7-8 parts of lily extract.

[0029] Further preferably, the peptide-containing composition comprises 4-5 parts or 5-6 parts of lily extract by weight.

[0030] Still further preferably, the peptide-containing composition comprises, by weight: 5 parts of lily extract.

[0031] Preferably, the peptide-containing composition comprises, by weight, 1-2 parts, 2-3 parts, 3-4 parts or 4-5 parts of licorice extract.

[0032] Further preferably, the peptide-containing composition comprises, by weight, 2-3 parts or 3-4 parts of liquorice extract.

[0033] Still further preferably, the peptide-containing composition comprises, by weight: 2 parts of licorice extract.

[0034] Preferably, the peptide-containing composition comprises, by weight, 5-6 parts, 6-7 parts, 7-8 parts, 8-9 parts, 9-10 parts, 10-11 parts or 11-12 parts of sea buckthorn fruit powder.

[0035] Further preferably, the peptide-containing composition comprises, by weight, 6-7 parts, 7-8 parts, 8-9 parts or 9-10 parts of sea buckthorn fruit powder.

[0036] Still further preferably, the peptide-containing composition comprises, by weight: 7 parts of sea buckthorn fruit powder.

[0037] Preferably, the peptide-containing composition comprises, by weight, 3-4 parts, 4-5 parts, 5-6 parts, 6-7 parts, 7-8 parts, 8-9 parts or 9-10 parts of polydextrose.

[0038] Further preferably, the peptide-containing composition comprises, by weight, 4-5 parts, 5-6 parts, 6-7 parts or 7-8 parts of polydextrose.

[0039] Still further preferably, the peptide-containing composition comprises, by weight: 6 parts of polydextrose.

[0040] Preferably, the peptide-containing composition comprises, by weight, 1-2 parts, 2-3 parts, 3-4 parts or 4-5 parts of xanthan gum.

[0041] Further preferably, the peptide-containing composition comprises 2-3 parts or 3-4 parts of xanthan gum by weight.

[0042] Still further preferably, the peptide-containing composition comprises, by weight: 2 parts of xanthan gum.

[0043] In another aspect, the present invention provides a method for preparing any of the above peptide-containing compositions.

[0044] Preferably, the preparation method comprises: mixing ginseng oligopeptides, donkey-hide gelatin peptides, bovine blood peptides, wolfberry peptides, fish collagen peptides, American ginseng peptides, lily extract, licorice extract, sea buckthorn fruit powder, polydextrose and xanthan gum in proportion to obtain the peptide-containing composition.

[0045] In another aspect, the present invention provides use of any of the above peptide-containing compositions in the preparation of products for improving qi and blood function, relieving fatigue, and enhancing immunity.

[0046] Preferably, the product includes any one or more of functional foods, health products and medicines.

[0047] In another aspect, the present invention provides a functional food, comprising any one of the above peptide-containing compositions.

[0048] Specifically, the dosage form of the functional food includes: solid dosage form, semi-solid dosage form or liquid dosage form.

[0049] Preferably, the functional food includes: candy, soy milk, yogurt, canned food, biscuits, chocolate, cakes, cream, cheese, milk powder, formula milk powder, ice cream, jam, puree, candied fruit, preserved fruit, bread, egg rolls, protein drinks, solid drinks, lactic acid bacteria drinks, plant protein drinks, carbonated drinks, coffee or puffed food.

[0050] Preferably, the functional food comprises human food or animal food.

[0051] Specifically, the functional food also includes nutritionally acceptable nutrients.

[0052] Preferably, the nutrients include any one or more of dietary fiber, polypeptides, medicinal and edible raw materials, proteins, lipids, minerals, and vitamins.

[0053] Specifically, the functional food also includes food-acceptable auxiliary materials.

[0054] Preferably, the excipients include: any one or a combination of two or more of wetting agents, emulsifiers, preservatives, antioxidants, buffers, diluents, lubricants, solvents, suspending agents, solubilizers, thickeners, stabilizers, sweeteners and spices.

[0055] Preferably, the functional food is used to improve qi and blood function, relieve fatigue or enhance immunity.

[0056] In another aspect, the present invention provides a health product comprising any one of the above peptide-containing compositions.

[0057] Specifically, the dosage forms of the health care product include: solid dosage forms, semi-solid dosage forms and liquid dosage forms.

[0058] Preferably, the dosage form of the health care product includes tablets, capsules, soft capsules, granules, pills, gel candies, powders, oral liquids or drops.

[0059] Specifically, the health care product also includes nutritionally acceptable nutrients.

[0060] Preferably, the nutrients include one or more of dietary fiber, polypeptides, medicinal and edible raw materials, proteins, lipids, minerals, and vitamins.

[0061] Specifically, the health care product also includes excipients acceptable for health care products.

[0062] Preferably, the excipients include: one or a combination of two or more of wetting agents, emulsifiers, preservatives, antioxidants, buffers, diluents, lubricants, solvents, suspending agents, solubilizers, thickeners, stabilizers, sweeteners and spices.

[0063] Preferably, the health care product is used to improve qi and blood function, relieve fatigue or enhance immunity.

[0064] In another aspect, the present invention provides a medicine comprising any one of the above peptide-containing combinations.

[0065] Specifically, the dosage forms of the drug include: tablets, pills, powders, suspensions, gels, emulsions, creams, granules, capsules, suppositories, injections, sprays or injections.

[0066] Specifically, the medicine further includes any one or more pharmaceutically acceptable excipients.

[0067] Preferably, the pharmaceutically acceptable excipients include: one or a combination of two or more of wetting agents, emulsifiers, preservatives, antioxidants, buffers, diluents, lubricants, solvents, suspending agents, solubilizers, thickeners, stabilizers, sweeteners and flavors.

[0068] Preferably, the medicine is used to prevent or treat qi and blood deficiency, prevent or treat iron deficiency anemia, relieve fatigue or enhance immunity.

[0069] In another aspect, the present invention provides a use of the functional food, health product or medicine described above, which comprises administering an effective amount of the functional food, health product or medicine to a subject.

[0070] Specifically, the subject is a mammal.

[0071] Preferably, the subject is a human.

[0072] In another aspect, the present invention provides a method for preventing or treating Qi and blood deficiency, preventing or treating iron deficiency anemia, improving Qi and blood function, relieving fatigue, or enhancing immunity.

[0073] Specifically, the method comprises administering an effective amount of functional food, health product or medicine to the subject.

[0074] Preferably, the subject is a mammal.

[0075] More preferably, the subject is a human.

[0076] The beneficial effects of the present invention are:

[0077] (1) The present invention has a formula for a peptide-containing composition that improves the function of Qi and blood. Small molecule peptides that have the effects of tonifying the spleen and replenishing Qi, nourishing the liver and kidneys, replenishing iron, and supplementing collagen are added. This not only has advantages in the absorption and utilization of the ingredients, but also has a more comprehensive and in-depth effect and mechanism of action in improving Qi and blood. Through the synergistic effect of multiple peptide components, it can promote the generation of Qi and blood and regulate the circulation of Qi and blood from multiple levels, while enhancing the body's immunity and improving the body's antioxidant capacity, providing a more effective solution for improving Qi and blood.

[0078] (2) The peptide composition of the present invention has a formula for improving the function of qi and blood, and is added with lily extract and licorice extract, both of which are medicinal and edible raw materials. They will not cause any harm to the organs and tissues of the body, and can nourish the lung qi, promote the circulation of qi and blood, regulate qi and activate blood circulation, promote the circulation of blood, and play a role in nourishing without stagnation.

[0079] (3) The peptide-containing composition of the present invention has a formula for improving the function of qi and blood. Polydextrose is added to regulate the intestinal flora, promote the intestinal absorption of other components, provide sufficient raw materials for the production of qi and blood, and thus improve the condition of insufficient qi and blood.

[0080] (4) The peptide-containing composition of the present invention has a formula for improving the function of qi and blood. The addition of xanthan gum can enhance the taste of the product, improve the stability of the product, and increase the acceptance of the product.

[0081] (5) The present invention has a formula for a peptide-containing composition that improves the function of qi and blood. The various functional ingredients added interact with each other to achieve the effects of regulating qi and blood and improving fatigue. In combination with the mechanism of action of the various functional ingredients, the peptides are scientifically and rationally matched for the purposes of replenishing qi and blood, resisting fatigue, and replenishing iron, thereby maximizing the efficacy of the peptides and comprehensively solving the problem of improving qi and blood. At the same time, animal blood-tonifying experiments show that the peptide-containing composition for improving qi and blood of the present invention can effectively replenish blood and improve qi and blood within the preferred range. Reducing or replacing the ingredients, as well as adjusting the ratio outside the preferred range, cannot achieve significant blood-tonifying and qi and blood-improving effects. DETAILED DESCRIPTION

[0082] To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the described embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0083] When numerical ranges are given in the examples, it should be understood that, unless otherwise specified herein, both endpoints of each numerical range and any value between the two endpoints may be selected. Unless otherwise defined, technical or scientific terms used herein shall have the same general meaning as those generally understood by persons of ordinary skill in the art to which this invention belongs.

[0084] It should be noted that the ginseng oligopeptide (20240618-1), donkey-hide gelatin peptide (20241223-3), bovine blood peptide (20240803-3), wolfberry peptide (20240127-1), fish collagen peptide (20241105-2), and American ginseng peptide (20240411-3) used in the present invention were all purchased from Anhui Shengminuo Biotechnology Co., Ltd.; lily extract and licorice extract were purchased from Shaanxi Xintianyu Biotechnology Co., Ltd.; xanthan gum was purchased from Zibo Zhongxuan Biochemical Co., Ltd., and the remaining raw materials are all common commercially available products, and their sources are not specifically limited.

[0085] Example 1

[0086] The peptide-containing composition of Example 1 comprises, by weight: 10 parts of ginseng oligopeptides, 15 parts of donkey-hide gelatin peptides, 8 parts of bovine blood peptides, 18 parts of wolfberry peptides, 12 parts of fish collagen peptides, 10 parts of American ginseng peptides, 8 parts of lily extracts, 5 parts of licorice extracts, 12 parts of sea buckthorn fruit powder, 3 parts of polydextrose and 1 part of xanthan gum.

[0087] The preparation method of the peptide-containing composition of Example 1 is as follows: ginseng oligopeptide, donkey-hide gelatin peptide, bovine blood peptide, wolfberry peptide, fish collagen peptide, American ginseng peptide, lily extract, licorice extract, sea buckthorn fruit powder, polydextrose and xanthan gum are mixed according to weight parts.

[0088] Example 2

[0089] The peptide-containing composition of Example 2 comprises, by weight: 15 parts of ginseng oligopeptide, 20 parts of donkey-hide gelatin peptide, 12 parts of bovine blood peptide, 15 parts of wolfberry peptide, 10 parts of fish collagen peptide, 8 parts of American ginseng peptide, 5 parts of lily extract, 2 parts of licorice extract, 7 parts of sea buckthorn fruit powder, 6 parts of polydextrose and 2 parts of xanthan gum.

[0090] The preparation method of the peptide-containing composition of Example 2 is the same as that of Example 1.

[0091] Example 3

[0092] The peptide-containing composition of Example 3 comprises, by weight: 20 parts of ginseng oligopeptides, 25 parts of donkey-hide gelatin peptides, 15 parts of bovine blood peptides, 10 parts of wolfberry peptides, 8 parts of fish collagen peptides, 5 parts of American ginseng peptides, 3 parts of lily extracts, 1 part of licorice extract, 5 parts of sea buckthorn fruit powder, 8 parts of polydextrose and 3 parts of xanthan gum.

[0093] The preparation method of the peptide-containing composition of Example 3 is the same as that of Example 1.

[0094] Example 4

[0095] The peptide-containing composition of Example 4 comprises, by weight: 25 parts of ginseng oligopeptide, 30 parts of donkey-hide gelatin peptide, 18 parts of bovine blood peptide, 20 parts of wolfberry peptide, 15 parts of fish collagen peptide, 12 parts of American ginseng peptide, 6 parts of lily extract, 3 parts of licorice extract, 10 parts of sea buckthorn fruit powder, 10 parts of polydextrose and 5 parts of xanthan gum.

[0096] The preparation method of the peptide-containing composition of Example 4 is the same as that of Example 1.

[0097] Comparative Example 1

[0098] The peptide-containing composition of Comparative Example 1 differs from that of Example 1 only in that bovine blood peptide and wolfberry peptide are not added.

[0099] The preparation method of the peptide-containing composition of Comparative Example 1 is as follows: ginseng oligopeptide, donkey-hide gelatin peptide, fish collagen peptide, American ginseng peptide, lily extract, licorice extract, sea buckthorn fruit powder, polydextrose and xanthan gum are mixed according to weight parts.

[0100] Comparative Example 2

[0101] The peptide-containing composition of Comparative Example 2 differs from that of Example 1 only in that lily extract and licorice extract are not added.

[0102] The preparation method of the peptide-containing composition of Comparative Example 2 is as follows: ginseng oligopeptide, donkey-hide gelatin peptide, bovine blood peptide, wolfberry peptide, fish collagen peptide, American ginseng peptide, sea buckthorn fruit powder, polydextrose and xanthan gum are mixed according to weight parts.

[0103] Comparative Example 3

[0104] The peptide-containing composition of Comparative Example 3 differs from that of Example 1 only in that no seabuckthorn fruit powder, polydextrose and xanthan gum are added.

[0105] The preparation method of the peptide-containing composition of Comparative Example 3 is as follows: ginseng oligopeptide, donkey-hide gelatin peptide, bovine blood peptide, wolfberry peptide, fish collagen peptide, American ginseng peptide, lily extract and licorice extract are mixed according to weight parts.

[0106] Comparative Example 4

[0107] The peptide-containing composition of Comparative Example 4 differs from that of Example 1 only in that the donkey-hide gelatin peptide is replaced by soybean peptide.

[0108] The preparation method of the peptide-containing composition of Comparative Example 4 is as follows: ginseng oligopeptide, soybean peptide, bovine blood peptide, wolfberry peptide, fish collagen peptide, American ginseng peptide, lily extract, licorice extract, sea buckthorn fruit powder, polydextrose and xanthan gum are mixed according to weight parts.

[0109] Comparative Example 5

[0110] The peptide-containing composition of Comparative Example 5 consists of, by weight, 10 parts of ginseng oligopeptide, 20 parts of donkey-hide gelatin peptide, 20 parts of bovine blood peptide, 25 parts of wolfberry peptide, 6 parts of fish collagen peptide, 4 parts of American ginseng peptide, 9 parts of lily extract, 6 parts of licorice extract, 15 parts of sea buckthorn fruit powder, 2 parts of polydextrose and 6 parts of xanthan gum.

[0111] The preparation method of the peptide-containing composition of Comparative Example 5 refers to Example 1.

[0112] Experimental Example 1 Blood-enriching effect test

[0113] 110 healthy male SD rats weighing 180-220g were collected. Ten rats were fed a normal basal diet and drinking water to serve as the normal control group. In addition to the normal control group, the remaining 100 rats were divided into 10 groups (model control group, Example 1-Example 4 groups, and Comparative Example 1-Comparative Example 5 groups), with 10 rats in each group. An anemia model was established by intraperitoneal injection of 80mg / kg of cyclophosphamide for three consecutive days. Blood was collected from the rats' orbits for measurement of hemoglobin (Hb) levels. Rats with Hb levels below 110g / L were considered to have successfully established anemia.

[0114] After the anemia model was established, rats in the Examples 1-4 and Comparative Examples 1-5 groups were gavaged with the peptide-containing compositions of Examples 1-4 and Comparative Examples 1-5 (prepared as solutions in normal saline) at a dose of 10 mL / kg once daily for 28 consecutive days. Rats in the normal control and model control groups were gavaged with an equal volume of normal saline.

[0115] Routine blood test: 28 days after administration, blood was collected from the rats' orbits under light ether anesthesia, and the red blood cell count (RBC), hemoglobin content (Hb), and hematocrit (HCT) were measured using a blood cell analyzer.

[0116] Data processing: The experimental data were expressed as mean ± standard deviation (x ± s), and SPSS statistical software was used to analyze the data. Variance analysis was used to compare the significant differences between the data, and the significance level used was 95% (p < 0.05).

[0117] Test results: The hemoglobin content of rats in each group before administration is shown in Table 1; the hemoglobin content, red blood cell count, and hematocrit of rats in each group after 28 days of administration are shown in Table 2; different lowercase letters in the table represent significant differences between the groups (p<0.05).

[0118] Table 1 Hemoglobin levels in rats in each group before administration

[0119]

[0120] Table 2 Hemoglobin content, red blood cell count, and hematocrit of rats in each group after administration

[0121]

[0122] The results showed that the peptide-containing compositions of Examples 1 to 4 significantly increased the number of red blood cells (RBC), hemoglobin content (Hb), and hematocrit (HCT) in the blood of anemic rats after administration, indicating that the peptide-containing compositions of Examples 1 to 4 of the present invention can achieve a good blood-enriching effect.

[0123] Comparative Examples 1-3 lacked two or three essential components, respectively. Comparative Example 4 replaced donkey-hide gelatin peptide with soybean peptide, and their blood-tonifying effects all declined to varying degrees. This indicates that if the peptide-containing composition of the present invention lacks one or more of these components, the technical effects will be impaired. It is worth noting that compared to the model control group, the Hb content in Comparative Examples 1-3 increased by 12.84 g / L, 28.07 g / L, and 43.16 g / L, respectively, while the Hb content in Example 1 increased by 90.86 g / L compared to the model control group. The peptide-containing composition of the present invention combines bovine blood peptide, wolfberry peptide, lily extract, licorice extract, sea buckthorn fruit powder, polydextrose, and xanthan gum, resulting in a synergistic effect (90.86 > 12.84 + 28.07 + 43.16).

[0124] Comparative Example 5 changes the dosage of some ingredients in Example 1, which shows that the best blood-enriching effect can be achieved only under the specific dosage of the present invention.

[0125] The above detailed description is a specific description of one feasible embodiment of the present invention and is not intended to limit the scope of the present invention. It should be noted that any equivalent implementation or modification that does not depart from the present invention should be included within the scope of the technical solution of the present invention. Therefore, the scope of protection of the patent of this invention should be based on the attached requirements.

Claims

1. A peptide-containing composition capable of improving qi and blood function, characterized in that: The peptide-containing composition consists of, by weight, 15 parts of ginseng oligopeptide, 20 parts of donkey-hide gelatin peptide, 12 parts of bovine blood peptide, 15 parts of wolfberry peptide, 10 parts of fish collagen peptide, 8 parts of American ginseng peptide, 5 parts of lily extract, 2 parts of liquorice extract, 7 parts of sea buckthorn fruit powder, 6 parts of polydextrose and 2 parts of xanthan gum.

2. The method for preparing the peptide-containing composition according to claim 1, characterized in that: The preparation method comprises: mixing ginseng oligopeptide, donkey-hide gelatin peptide, bovine blood peptide, wolfberry peptide, fish collagen peptide, American ginseng peptide, lily extract, liquorice extract, seabuckthorn fruit powder, polydextrose and xanthan gum in proportion to obtain the peptide-containing composition.

3. Use of the peptide-containing composition according to claim 1 in the preparation of functional foods or health products for improving qi and blood functions.

4. A functional food or health product, characterized in that: The functional food or health product comprises the peptide-containing composition according to claim 1.

5. The functional food or health product according to claim 4, characterized in that The dosage forms of the functional food or health product include solid dosage forms, semisolid dosage forms or liquid dosage forms.

6. The functional food or health product according to claim 4, characterized in that The functional food or health product also includes nutritionally acceptable nutrients.

7. The functional food or health product according to claim 6, characterized in that The nutrients include any one or more of dietary fiber, polypeptides, medicinal and edible raw materials, proteins, lipids, minerals, and vitamins.

8. The functional food or health product according to claim 4, characterized in that The functional food or health product also includes auxiliary materials acceptable to food or health product.

9. The functional food or health product according to claim 8, characterized in that The auxiliary materials include: any one or a combination of two or more of wetting agents, emulsifiers, preservatives, antioxidants, buffers, diluents, lubricants, solvents, suspending agents, solubilizers, thickeners, stabilizers, sweeteners and spices.

10. The functional food or health product according to claim 4, characterized in that The functional food or health product is used to improve the function of qi and blood.

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