Du meridian powder and preparation method thereof

Abstract

The invention belongs to the technical field of biological medicines, and relates to governor meridian powder and a preparation method thereof. The invention provides governor meridian powder. The governor meridian powder is prepared from the following powdery components: ginseng, coptis chinensis, obscured homalomena rhizome, cortex illicii, sulfur, berchemia sinica, peach kernel, safflower, lignum dalbergiae odoriferae, radix aucklandiae, garden balsam stem, lycopodium clavatum, myrrh, rhizoma atractylodis, radix clematidis, caulis spatholobi, sargentgloryvine stem, vernonia graveolens, entada phaseoloides, folium artemisiae argyi, sculellaria barbata, folium photiniae and liquorice. The governor meridian powder is used for governor meridian moxibustion, the governor meridian powder and ginger are sequentially laid on the back of a human body, and moxa is ignited for use. The governor meridian powder provided by the invention can improve the effective rate and improvement speed of governor meridian moxibustion.

Description

Technical Field

[0001] The present invention belongs to the technical field of biomedicine and relates to a Du Meridian powder and a preparation method thereof. Background Art

[0002] Du Meridian moxibustion, also known as Du Meridian moxibustion (keel moxibustion), refers to a characteristic therapy of applying "moxibustion with herbal cake separation" on the spinal segment of the Du Meridian to treat diseases. It is a green, safe and highly effective external treatment method of traditional Chinese medicine. Because it is in the shape of a long snake, it is also called "long snake moxibustion". Traditional Chinese medicine emphasizes "conforming to the timing of nature and the unity of man and nature". During the dog days, the weather in nature is hot and yang qi is abundant, and the qi and blood of the human body are strong and the pores are enlarged. At this time, performing Du Meridian moxibustion can better promote the effect of moxibustion, thereby enhancing physical fitness, improving the body's disease resistance, and preventing diseases and maintaining health. The location of Du Meridian moxibustion is on the Du Meridian. The Du Meridian is one of the eight extraordinary meridians in the human body, governing all yang meridians of the body. Six yang meridians all intersect with the Du Meridian at Dazhui acupoint, and the Du Meridian has the function of regulating the yang qi of the whole body, so it is called the "sea of yang meridians". During treatment, the functions of the Du Meridian, traditional Chinese medicine (Du Meridian powder, or Du Meridian moxibustion powder), ginger, moxa wool, etc. are combined to give full play to the multiple synergistic effects of meridians, acupoints, drugs, moxibustion methods, etc. The power is so great that it cannot be achieved by ordinary moxibustion methods. Therefore, Du Meridian moxibustion is called the "king of moxibustion". The applicable diseases of Du Meridian moxibustion are as follows: (1) Yang deficiency constitution, such as fear of cold, frequent urination at night, diarrhea at dawn, heel, waist and leg pain, hair loss, insomnia, upper heat and lower cold, depression, etc. (2) Cold syndromes, such as cold body and cold limbs, pale complexion, no thirst, or preference for warm drinks, quiet and seldom talk, clear and long urine, loose stools, etc. (3) Rheumatic diseases, such as spinal joint diseases like ankylosing spondylitis, rheumatoid arthritis, etc. (4) Gynecological reproductive diseases, such as dysmenorrhea, irregular menstruation, cold uterus, habitual abortion, etc. (5) Digestive diseases, such as chronic atrophic gastritis, chronic diarrhea, constipation caused by qi deficiency and yang deficiency, gastrointestinal dysfunction, stomach cold, etc.

[0003] Du Meridian moxibustion starts from warming and tonifying the yang qi of the human body, selects the most fiery moxibustion method, directly uses the fiery nature from the outside world to stimulate the yang qi of the sea of yang meridians in the human body, to communicate yin and yang, regulate the triple energizer, and finally enable patients with yang deficiency constitution to reach the state of a healthy person with "yin and yang in balance". At present, the Du Meridian powder used in Du Meridian moxibustion generally consists of 9 traditional Chinese medicines, namely raw Radix Aconiti Kusnezoffii, raw Radix Aconiti Carmichaeli, Rhizoma seu Radix Notopterygii, Radix Angelicae Pubescentis, Cortex Cinnamomi, Herba Asari, Flos Caryophylli, Zanthoxylum bungeanum, and ginger. It has problems of low efficiency (generally about 50%) and poor improvement speed (generally, it takes 10 times of Du Meridian moxibustion in 2 courses of treatment to show significant improvement). Summary of the Invention

[0004] The purpose of the present invention is to solve the problems that the commonly used Du Meridian powder in Du Meridian moxibustion at present has low efficiency (generally about 50%) and poor improvement speed (generally, it takes 10 times of Du Meridian moxibustion in 2 courses of treatment to show significant improvement). In this regard, the present invention provides a Du Meridian powder and a preparation method thereof to meet this need in the field.

[0005] On the one hand, the present invention relates to a Du Meridian powder, which is composed of the following powdery components: ginseng, coptis, homalomena occulta, piper kadsura, sulfur, aconitum pendulum, peach kernel, safflower, dalbergia odorifera, costus root, divaricate saposhnikovia root, lycopodium clavatum, myrrh, atractylodes lancea, clematis chinensis, millettia reticulata, rattan palm, climbing entada stem, Chinese mugwort leaf, scutellaria barbata, photinia serrulata leaf and liquorice;

[0006] Any component in the Du Meridian powder is made into powder after being processed or unprocessed.

[0007] Further, in the Du Meridian powder provided by the present invention, the Du Meridian powder is composed of 4 layers of powdery components from top to bottom in sequence;

[0008] The first layer is composed of the following powdery components: ginseng, coptis, homalomena occulta, piper kadsura, sulfur, aconitum pendulum, peach kernel, safflower and dalbergia odorifera;

[0009] The second layer is composed of the following powdery components: costus root, divaricate saposhnikovia root, lycopodium clavatum, myrrh and atractylodes lancea;

[0010] The third layer is composed of the following powdery components: clematis chinensis, millettia reticulata, rattan palm, climbing entada stem and Chinese clematis stem;

[0011] The fourth layer is composed of the following powdery components: Chinese mugwort leaf, scutellaria barbata, photinia serrulata leaf and liquorice.

[0012] Further, in the Du Meridian powder provided by the present invention, the Du Meridian powder is composed of the following powdery components in parts by weight: 50 - 70 parts of ginseng, 10 - 30 parts of coptis, 10 - 30 parts of homalomena occulta, 10 - 30 parts of piper kadsura, 10 - 30 parts of sulfur, 10 - 30 parts of aconitum pendulum, 10 - 30 parts of peach kernel, 20 - 40 parts of safflower, 10 - 20 parts of dalbergia odorifera, 10 - 20 parts of costus root, 20 - 40 parts of divaricate saposhnikovia root, 20 - 40 parts of lycopodium clavatum, 20 - 40 parts of myrrh, 90 - 110 parts of atractylodes lancea, 20 - 40 parts of clematis chinensis, 40 - 60 parts of millettia reticulata, 50 - 70 parts of rattan palm, 40 - 60 parts of climbing entada stem, 40 - 60 parts of Chinese clematis stem, 90 - 110 parts of Chinese mugwort leaf, 40 - 60 parts of scutellaria barbata, 40 - 60 parts of photinia serrulata leaf and 10 - 30 parts of liquorice.

[0013] Further, in the Du Meridian powder provided by the present invention, the Du Meridian powder is composed of the following powdery components in parts by weight: 60 parts of ginseng, 20 parts of coptis, 20 parts of homalomena occulta, 20 parts of piper kadsura, 20 parts of sulfur, 20 parts of aconitum pendulum, 20 parts of peach kernel, 30 parts of safflower, 15 parts of dalbergia odorifera, 15 parts of costus root, 30 parts of divaricate saposhnikovia root, 30 parts of lycopodium clavatum, 30 parts of myrrh, 100 parts of atractylodes lancea, 30 parts of clematis chinensis, 50 parts of millettia reticulata, 60 parts of rattan palm, 50 parts of climbing entada stem, 50 parts of Chinese clematis stem, 100 parts of Chinese mugwort leaf, 50 parts of scutellaria barbata, 50 parts of photinia serrulata leaf and 20 parts of liquorice.

[0014] On the other hand, the present invention relates to a method for preparing the said Du Meridian powder, which includes: drying ginseng and licorice to make powder, and washing and making powder of scutellaria barbata and photinia serratifolia;

[0015] After processing coptis chinensis, homalomena occulta, piper wallichii, sulfur, aconitum pendulum, peach kernel, safflower, dalbergia odorifera, costus root, divaricate saposhnikovia root, lucid ganoderma, myrrh, atractylodes lancea, clematis chinensis, millettia reticulata, rattan palm, clematis armandii and artemisia argyi, grinding them into powder, and storing all components sealed for at least 7 days to obtain the said Du Meridian powder.

[0016] Further, in the method for preparing the said Du Meridian powder provided by the present invention, all the components are mixed and then stored sealed.

[0017] Further, in the method for preparing the said Du Meridian powder provided by the present invention, ginseng, coptis chinensis, homalomena occulta, piper wallichii, sulfur, aconitum pendulum, peach kernel, safflower and dalbergia odorifera are mixed and then stored sealed;

[0018] Costus root, divaricate saposhnikovia root, lucid ganoderma, myrrh and atractylodes lancea are mixed and then stored sealed;

[0019] Clematis chinensis, millettia reticulata, rattan palm, clematis armandii and piper wallichii are mixed and then stored sealed;

[0020] Artemisia argyi, scutellaria barbata, photinia serratifolia and licorice are mixed and then stored sealed.

[0021] On the other hand, the present invention relates to the application of the said Du Meridian powder in the preparation of medicaments for Du Meridian moxibustion.

[0022] Compared with the prior art, the technical solution provided by the present invention has at least the following beneficial effects or advantages:

[0023] The compatibility principle of the present invention is to warm the Yang and open the Governor Vessel, and guide the medicine to the meridian. Sulfur (very hot) and mugwort leaf (spicy and warm) are the main drugs, which directly enter the Governor Vessel with their warm nature, help Yang and dispel cold. Photinia leaf (spicy and warm) specifically enters the Governor Vessel. The Compendium of Materia Medica records that it "penetrates the Yang Qi of the Governor Vessel". Mugwort leaf has both the function of warming the meridian and the function of a carrier, and promotes the transdermal absorption of drugs; dispels wind and dampness, and relaxes muscles and activates collaterals. Qiannianjian + Zhuidifeng + Clematis: dispels deep rheumatism, especially good at treating muscle and bone pain, tonggucao + spatholobi + guoshanlong + guojianglong: form a "penetrate-stretch-pass" medicine group, and play the effect of loosening fascia adhesion; Atractylodes (drying dampness) + costusroot (moving qi) constitute the synergistic effect of "wind overcomes dampness, qi moves dampness"; promotes blood circulation and removes blood stasis, dredges the collaterals and relieves pain. Peach kernel + safflower + myrrh: a classic combination of promoting blood circulation and removing blood stasis, improving microcirculation; Millettia reticulata + red vine: vine drugs are good at running through the meridians, and can also replenish blood and promote blood circulation; Iron club (Artemisia scoparia): highly toxic but can strongly relieve pain when used externally, and requires strict preparation and compatibility. It has the following compatibility characteristics: cold and hot are used together to prevent dryness, Coptis chinensis + Scutellaria barbata (bitter and cold) counteract sulfur, mugwort and other hot products to prevent warm dryness from damaging yin, licorice harmonizes the cold and hot properties of various drugs, and can also detoxify and relieve urgency; Qi and blood are coordinated to increase the efficacy of the drug, ginseng (replenishing qi) + aloeswood (promoting qi) forms a synergistic mechanism of "qi is sufficient and blood flows", costus root + aloeswood: one rises and one falls, regulating qi to help blood circulation; dynamic and static combination promotes penetration, bone-penetrating grass + stretch grass (dynamic): open the pores and increase transdermal absorption, atractylodes + sulfur (static): form a drug sustained-release matrix. This prescription embodies the characteristics of external treatment of the Du channel of "warming and promoting circulation as the basis, and penetrating and reaching as the purpose", and achieves the unity of local penetration and overall regulation through the synergistic effect of multiple targets, which is in line with the design concept of modern transdermal drug delivery system (TDDS). DETAILED DESCRIPTION

[0024] The technical scheme of the present invention is described below in conjunction with the embodiments, but the present invention is not limited to the following embodiments. The experimental methods and detection methods described in each embodiment are conventional methods unless otherwise specified; the reagents and materials described are available on the market unless otherwise specified. The % in the following embodiments are all mass percentages unless otherwise specified. The ratios in the following embodiments are all mass ratios unless otherwise specified.

[0025] In the following embodiments, ginseng, coptis, homalomena occulta, piper wallichii, sulfur, aconitum szechenyianum gay, peach kernel, safflower, dalbergia odorifera, costus root, speranskia tuberculata, lycopodium clavatum, myrrh, atractylodes lancea, clematis chinensis, millettia reticulata, rattan palm, clematis armandii, polygonum perfoliatum, artemisia argyi, scutellaria barbata, photinia serrulata, and licorice were all purchased from Bozhou Boyuan Pharmaceutical Co., Ltd. Among them, ginseng and licorice were dried and made into powder, and scutellaria barbata and photinia serrulata were washed and made into powder; coptis (processed with ginger juice), homalomena occulta (steamed + simmered), piper wallichii (processed with wine), sulfur (boiled with licorice juice), aconitum szechenyianum gay (soaked in white liquor + slightly stir-fried), peach kernel (slightly stir-fried + processed with wine), safflower (slightly stir-fried + processed with wine), dalbergia odorifera (processed with tea, wine, and honey dates), costus root (fried with wheat bran), speranskia tuberculata (processed with wine), lycopodium clavatum (processed with wine), myrrh (processed with vinegar), atractylodes lancea (fried with rice-washing water), clematis chinensis (processed with wine), millettia reticulata (processed with wine), rattan palm (fried with rice vinegar), clematis armandii (processed with wine), polygonum perfoliatum, artemisia argyi (fried with vinegar), scutellaria barbata, and photinia serrulata were processed, and the specific processing methods refer to the Pharmacopoeia of the People's Republic of China (2020 Edition) and Chinese Medicinal Processing Science.

[0026] Example 1

[0027] This example provides a preparation process of Du Meridian powder.

[0028] A kind of Du Meridian powder, calculated by weight, the raw materials for preparation are composed of 50 parts of ginseng, 10 parts of coptis, 10 parts of homalomena occulta, 10 parts of piper wallichii, 10 parts of sulfur, 10 parts of aconitum szechenyianum gay, 10 parts of peach kernel, 20 parts of safflower, 10 parts of dalbergia odorifera, 10 parts of costus root, 20 parts of speranskia tuberculata, 20 parts of lycopodium clavatum, 20 parts of myrrh, 900 parts of atractylodes lancea, 20 parts of clematis chinensis, 40 parts of millettia reticulata, 50 parts of rattan palm, 40 parts of clematis armandii, 40 parts of polygonum perfoliatum, 900 parts of artemisia argyi, 40 parts of scutellaria barbata, 40 parts of photinia serrulata, and 10 parts of licorice.

[0029] Ginseng and licorice were dried and made into powder; after coptis, homalomena occulta, piper wallichii, sulfur, aconitum szechenyianum gay, peach kernel, safflower, dalbergia odorifera, costus root, speranskia tuberculata, lycopodium clavatum, myrrh, atractylodes lancea, clematis chinensis, millettia reticulata, rattan palm, clematis armandii, polygonum perfoliatum, artemisia argyi, scutellaria barbata, and photinia serrulata were processed, they were ground into powder, and all components were sealed and stored for 7 days to obtain the Du Meridian powder.

[0030] When in use, for moxibustion on the Du Meridian with ginger slices, sprinkle the Du Meridian powder on the skin.

[0031] Example 2

[0032] This example provides a preparation process of Du Meridian powder.

[0033] A Du Meridian powder, calculated by weight, is composed of the following raw materials for preparation: 60 parts of ginseng, 20 parts of Coptis chinensis, 20 parts of Homalomena occulta, 20 parts of Lysimachia christinae, 20 parts of sulfur, 20 parts of Aconitum pendulum, 20 parts of peach kernels, 30 parts of safflower, 15 parts of dalbergia odorifera, 15 parts of Aucklandia lappa, 30 parts of speranskia tuberculata, 30 parts of lycopodium clavatum, 30 parts of myrrh, 100 parts of Atractylodes lancea, 30 parts of Clematis chinensis, 50 parts of Caulis Spatholobi, 60 parts of Sargentodoxa cuneata, 50 parts of Ampelopsis brevipedunculata, 50 parts of Trachelospermum jasminoides, 100 parts of Artemisia argyi, 50 parts of Scutellaria barbata, 50 parts of Photinia serratifolia, and 20 parts of licorice.

[0034] Dry the ginseng and licorice to make powder; after processing the Coptis chinensis, Homalomena occulta, Lysimachia christinae, sulfur, Aconitum pendulum, peach kernels, safflower, dalbergia odorifera, Aucklandia lappa, speranskia tuberculata, lycopodium clavatum, myrrh, Atractylodes lancea, Clematis chinensis, Caulis Spatholobi, Sargentodoxa cuneata, Ampelopsis brevipedunculata, Trachelospermum jasminoides, Artemisia argyi, Scutellaria barbata, Photinia serratifolia, grind them into powder, and obtain the Du Meridian powder after sealing and storing all components for 7 days.

[0035] When in use, perform ginger moxibustion on the Du Meridian and sprinkle the Du Meridian powder on the skin.

[0036] Example 3

[0037] This example provides a preparation process of a Du Meridian powder.

[0038] A Du Meridian powder, calculated by weight, is composed of the following raw materials for preparation: 70 parts of ginseng, 30 parts of Coptis chinensis, 30 parts of Homalomena occulta, 30 parts of Lysimachia christinae, 30 parts of sulfur, 30 parts of Aconitum pendulum, 30 parts of peach kernels, 40 parts of safflower, 20 parts of dalbergia odorifera, 20 parts of Aucklandia lappa, 40 parts of speranskia tuberculata, 40 parts of lycopodium clavatum, 40 parts of myrrh, 110 parts of Atractylodes lancea, 40 parts of Clematis chinensis, 60 parts of Caulis Spatholobi, 70 parts of Sargentodoxa cuneata, 60 parts of Ampelopsis brevipedunculata, 60 parts of Trachelospermum jasminoides, 110 parts of Artemisia argyi, 60 parts of Scutellaria barbata, 60 parts of Photinia serratifolia, and 30 parts of licorice.

[0039] Dry the ginseng and licorice to make powder; after processing the Coptis chinensis, Homalomena occulta, Lysimachia christinae, sulfur, Aconitum pendulum, peach kernels, safflower, dalbergia odorifera, Aucklandia lappa, speranskia tuberculata, lycopodium clavatum, myrrh, Atractylodes lancea, Clematis chinensis, Caulis Spatholobi, Sargentodoxa cuneata, Ampelopsis brevipedunculata, Trachelospermum jasminoides, Artemisia argyi, Scutellaria barbata, Photinia serratifolia, grind them into powder, and obtain the Du Meridian powder after sealing and storing all components for 7 days.

[0040] When in use, perform ginger moxibustion on the Du Meridian and sprinkle the Du Meridian powder on the skin.

[0041] Example 4

[0042] This example provides a preparation process of a Du Meridian powder.

[0043] A Du Meridian powder, calculated by weight, is composed of the following raw materials for preparation: 50 parts of ginseng, 10 parts of coptis, 10 parts of homalomena occulta, 10 parts of piper wallichii, 10 parts of sulfur, 10 parts of aconitum pendulum, 10 parts of peach kernel, 20 parts of safflower, 10 parts of dalbergia odorifera, 10 parts of costus root, 20 parts of divaricate saposhnikovia root, 20 parts of lucid ganoderma mycelium, 20 parts of myrrh, 900 parts of atractylodes lancea, 20 parts of clematis chinensis, 40 parts of suberect spatholobus stem, 50 parts of rattan of erythrina thomsonii, 40 parts of clematis armandii, 40 parts of celastrus orbiculatus, 900 parts of artemisia argyi, 40 parts of scutellaria barbata, 40 parts of photinia serrulata and 10 parts of liquorice.

[0044] Mix ginseng, coptis, homalomena occulta, piper wallichii, sulfur, aconitum pendulum, peach kernel, safflower and dalbergia odorifera, and then store them sealed.

[0045] Mix costus root, divaricate saposhnikovia root, lucid ganoderma mycelium, myrrh and atractylodes lancea, and then store them sealed.

[0046] Mix clematis chinensis, suberect spatholobus stem, rattan of erythrina thomsonii, clematis armandii and celastrus orbiculatus, and then store them sealed.

[0047] Mix artemisia argyi, scutellaria barbata, photinia serrulata and liquorice, and then store them sealed.

[0048] When in use, for moxibustion on the Du Meridian with ginger slices, sprinkle the Du Meridian powder on the skin in contact. The Du Meridian powder is composed of 4 layers of powdery components from top to bottom in sequence;

[0049] The first layer is composed of the following powdery components: ginseng, coptis, homalomena occulta, piper wallichii, sulfur, aconitum pendulum, peach kernel, safflower and dalbergia odorifera;

[0050] The second layer is composed of the following powdery components: costus root, divaricate saposhnikovia root, lucid ganoderma mycelium, myrrh and atractylodes lancea;

[0051] The third layer is composed of the following powdery components: clematis chinensis, suberect spatholobus stem, rattan of erythrina thomsonii, clematis armandii and celastrus orbiculatus;

[0052] The fourth layer is composed of the following powdery components: artemisia argyi, scutellaria barbata, photinia serrulata and liquorice.

[0053] Example 5

[0054] This example provides a preparation process of a Du Meridian powder.

[0055] A Du Meridian powder, calculated by weight, is composed of the following raw materials for preparation: 60 parts of ginseng, 20 parts of coptis, 20 parts of homalomena occulta, 20 parts of piper wallichii, 20 parts of sulfur, 20 parts of aconitum pendulum, 20 parts of peach kernel, 30 parts of safflower, 15 parts of dalbergia odorifera, 15 parts of costus root, 30 parts of divaricate saposhnikovia root, 30 parts of lucid ganoderma mycelium, 30 parts of myrrh, 100 parts of atractylodes lancea, 30 parts of clematis chinensis, 50 parts of suberect spatholobus stem, 60 parts of rattan of erythrina thomsonii, 50 parts of clematis armandii, 50 parts of celastrus orbiculatus, 100 parts of artemisia argyi, 50 parts of scutellaria barbata, 50 parts of photinia serrulata and 20 parts of liquorice.

[0056] Ginseng and liquorice are dried and made into powder; Coptis chinensis, Homalomena occulta, Lysimachia paridiformis, sulfur, Aconitum pendulum, peach kernel, safflower, dalbergia odorifera, Aucklandia lappa, Speranskia tuberculata, Lycopodium clavatum, myrrh, Atractylodes lancea, Clematis chinensis, Spatholobus suberectus, Sargentodoxa cuneata, Ampelopsis brevipedunculata, Saururus chinensis, Artemisia argyi, Scutellaria barbata, and Photinia serrulata are processed and then ground into powder. After all components are sealed and stored for 7 days, the said Governor Vessel powder is obtained.

[0057] When in use, for moxibustion on the Governor Vessel with ginger partition, the Governor Vessel powder is sprinkled on the skin. The Governor Vessel powder is composed of 4 layers of powdery components from top to bottom;

[0058] The first layer is composed of the following powdery components: ginseng, Coptis chinensis, Homalomena occulta, Lysimachia paridiformis, sulfur, Aconitum pendulum, peach kernel, safflower, and dalbergia odorifera;

[0059] The second layer is composed of the following powdery components: Aucklandia lappa, Speranskia tuberculata, Lycopodium clavatum, myrrh, and Atractylodes lancea;

[0060] The third layer is composed of the following powdery components: Clematis chinensis, Spatholobus suberectus, Sargentodoxa cuneata, Ampelopsis brevipedunculata, and Saururus chinensis;

[0061] The fourth layer is composed of the following powdery components: Artemisia argyi, Scutellaria barbata, Photinia serrulata, and liquorice.

[0062] Example 6

[0063] This example provides a preparation process of the Governor Vessel powder.

[0064] A kind of Governor Vessel powder, calculated by weight, the preparation raw materials are composed of 70 parts of ginseng, 30 parts of Coptis chinensis, 30 parts of Homalomena occulta, 30 parts of Lysimachia paridiformis, 30 parts of sulfur, 30 parts of Aconitum pendulum, 30 parts of peach kernel, 40 parts of safflower, 20 parts of dalbergia odorifera, 20 parts of Aucklandia lappa, 40 parts of Speranskia tuberculata, 40 parts of Lycopodium clavatum, 40 parts of myrrh, 110 parts of Atractylodes lancea, 40 parts of Clematis chinensis, 60 parts of Spatholobus suberectus, 70 parts of Sargentodoxa cuneata, 60 parts of Ampelopsis brevipedunculata, 60 parts of Saururus chinensis, 110 parts of Artemisia argyi, 60 parts of Scutellaria barbata, 60 parts of Photinia serrulata, and 30 parts of liquorice.

[0065] Ginseng and liquorice are dried and made into powder; Coptis chinensis, Homalomena occulta, Lysimachia paridiformis, sulfur, Aconitum pendulum, peach kernel, safflower, dalbergia odorifera, Aucklandia lappa, Speranskia tuberculata, Lycopodium clavatum, myrrh, Atractylodes lancea, Clematis chinensis, Spatholobus suberectus, Sargentodoxa cuneata, Ampelopsis brevipedunculata, Saururus chinensis, Artemisia argyi, Scutellaria barbata, and Photinia serrulata are processed and then ground into powder. After all components are sealed and stored for 7 days, the said Governor Vessel powder is obtained.

[0066] When in use, for moxibustion on the Governor Vessel with ginger partition, the Governor Vessel powder is sprinkled on the skin. The Governor Vessel powder is composed of 4 layers of powdery components from top to bottom;

[0067] The first layer is composed of the following powdery components: ginseng, Coptis chinensis, Homalomena occulta, Lysimachia paridiformis, sulfur, Aconitum pendulum, peach kernel, safflower, and dalbergia odorifera;

[0068] The second layer consists of the following powdery components: Aucklandia lappa, Speranskia tuberculata, Lycopodium clavatum, Myrrh, and Atractylodes lancea;

[0069] The third layer consists of the following powdery components: Clematis chinensis, Millettia reticulata, Sargentodoxa cuneata, Shandong clematis root, and Trachelospermum jasminoides;

[0070] The fourth layer consists of the following powdery components: Artemisia argyi, Scutellaria barbata, Photinia serrulata leaves, and Glycyrrhiza uralensis.

[0071] Comparative Example 1

[0072] This comparative example is a conventional Du Meridian powder, which is composed of the powders of 9 traditional Chinese medicines, namely Aconitum carmichaelii, Aconitum kusnezoffii, Notopterygium incisum, Angelica pubescens, Cinnamomum cassia, Asarum sieboldii, Eugenia caryophyllata, Zanthoxylum bungeanum, and Zingiber officinale, all purchased from Bozhou Boyuan Pharmaceutical Co., Ltd. By mass percentage, the components are as follows: Aconitum carmichaelii 5%, Aconitum kusnezoffii 5%, Notopterygium incisum 10%, Angelica pubescens 10%, Cinnamomum cassia 10%, Asarum sieboldii 5%, Eugenia caryophyllata 5%, Zanthoxylum bungeanum 5%, and Zingiber officinale 25%.

[0073] Comparative Example 2

[0074] This comparative example is the same as Example 2, except that it does not contain Dalbergia odorifera.

[0075] Test Example

[0076] Refer to "Traditional Chinese Medicine Constitutionology" (edited by Wang Qi) and the national constitution standard "Traditional Chinese Medicine Constitution Classification and Judgment Table" promulgated by the China Association of Chinese Medicine. Answer all the questions in the "Traditional Chinese Medicine Constitution Classification and Judgment Table". Each question is scored on a 5-point scale. Calculate the original score and the converted score, and determine the constitution type according to the standard. Combining with traditional Chinese medicine symptoms, it can be determined that this constitution is the yang deficiency constitution. After intervention, re-evaluate the yang deficiency constitution score and conduct statistics.

[0077] Refer to the "Guiding Principles for Clinical Research of New Traditional Chinese Medicines" to formulate an integral standard. Score according to the five levels of "asymptomatic; mild; obvious; severe; very severe". The main symptom of fear of cold and cold limbs is scored according to the 2-4-6-8-10 dimension, and the secondary symptoms are scored according to the 1-2-3-4-5 dimension. Those with normal tongue and pulse are scored 0 points, those with other tongue and pulse manifestations except yang deficiency are scored 1 point, and those who meet the yang deficiency tongue and pulse manifestations are scored 2 points. Refer to the "Guiding Principles for Clinical Research of New Traditional Chinese Medicines", and according to the change of traditional Chinese medicine symptom scores, calculate the curative effect index (n) = (traditional Chinese medicine symptom score before treatment - traditional Chinese medicine symptom score after treatment) / traditional Chinese medicine symptom score before treatment × 100%. When n > 70% is considered markedly effective, 30% < n < 70% is considered effective, n < 30% is considered ineffective, and n < 0 is considered aggravated.

[0078] A total of 60 patients with yang deficiency constitution participated in the trial, including 33 females and 27 males, with an average age of 46 years. Contraindications to governor vessel moxibustion treatment were excluded. 20 people were treated with the prescriptions of Examples 1 to 3, and the dosages of each component were adjusted according to symptoms; 20 people were treated with the prescriptions of Examples 4 to 6, and the dosages of each component were adjusted according to symptoms; 10 people were treated with the prescription of Comparative Example 1; 10 people were treated with the prescription of Comparative Example 2. A total of 10 moxibustion treatments were given, with an interval of 5 to 7 days between each moxibustion treatment.

[0079] The determination of the improvement in curative effect is shown in Table 1.

[0080] Table 1: Determination of the improvement in TCM symptoms after governor vessel moxibustion treatment (cases)

[0081]

[0082] According to the data in Table 1, at the first moxibustion treatment, the effective rate of the prescriptions of Examples 4 - 6 was 60% (12 / 20 cases), which was much higher than 0% (0 / 10 cases) of Comparative Example 1 and 10% (1 / 10 cases) of Comparative Example 2. After all moxibustion treatments were completed, the total effective rate (marked effect + effective) of the prescriptions of Examples 1 - 3 reached 95% (19 / 20 cases), the prescriptions of Examples 4 - 6 achieved 100% (20 / 20 cases), while Comparative Example 1 and Comparative Example 2 were only 40% (4 / 10 cases) and 60% (6 / 10 cases) respectively. In typical cases, after being treated with the governor vessel powder of the present invention, complex symptoms such as limited knee joint movement, ankylosing spondylitis, sinusitis, amenorrhea, etc. of the patients were significantly improved. Some patients showed symptom relief after the first moxibustion treatment, and no aggravated cases were observed, highlighting its rapid onset and safety. The effective rate of the conventional governor vessel powder in the prior art (Comparative Example 1) was only 50% and required 2 treatment courses, while the present invention achieved multi-target synergistic effects through hierarchical drug layout (four-layer structure), combination of cold and hot herbs (synergy of sulfur and coptis), dynamic and static combination transdermal mechanism (complementation of speranskia tuberculata and atractylodes lancea), and strict processing technology, significantly improving the transdermal absorption efficiency of the drug and the overall regulation ability. Finally, the effective rate was increased to 95 - 100%, the treatment course was shortened to within 10 times of a single treatment course, and the scope of indications was wider. In addition, the effective rate of Comparative Example 2 (lacking dalbergia odorifera) decreased significantly, verifying the necessity of the "qi promoting blood circulation" compatibility design in the prescription of the present invention. In summary, through innovative prescription and process optimization, the present invention breaks through the limitations of the prior art in terms of effective rate, improvement speed, safety, and scope of indications, providing a better solution for governor vessel moxibustion therapy.

[0083] Typical cases

[0084] (1) Su XX, female, 51 years old

[0085] Uncomfortable symptoms: pain, swelling, and stiffness in the right leg, and the knee cannot bend when walking. The syndrome belongs to spleen deficiency leading to prior deficiency of liver and kidney, loss of nourishment of tendons, bones, and muscles, poor qi and blood circulation, and retention of cold-damp pathogens in the joints, resulting in joint pain and swelling.

[0086] Treatment: The treatment mainly focuses on tonifying the liver and kidneys. At the beginning, the acupoints selected are mainly on the Governor Vessel. Ginger-separated moxibustion is applied to the Governor Vessel, and the Governor Vessel powder is sprinkled on the skin (Example 4). The moxibustion is carried out for 50 minutes. During the first moxibustion, there is heat conduction in the left leg, and there is no warm feeling in the right leg. After the moxibustion, there is discomfort and a feeling of dry heat below the knees, and large moxibustion blisters also appear on the liver, gallbladder, spleen, and stomach. After several sessions of Governor Vessel moxibustion, the leg pain is significantly improved, the knees can bend normally, and the movement is flexible. In the later stage, local moxibustion treatment is combined to strengthen the healthy qi and eliminate pathogenic factors, and regulate qi and blood.

[0087] (2) Zhu X, male, 47 years old

[0088] Symptoms of discomfort: Ankylosing spondylitis (diagnosed in the hospital) for many years, with a stiff neck, pain in the lower back, chest, a hunched back, and difficulty getting up and lying down. The disease belongs to arthralgia syndrome, due to deficiency of the liver and kidneys, malnutrition of the meridians, stagnation of qi and blood, malnutrition of the limbs, and a combination of wind, cold, and damp pathogens invading while taking advantage of the deficiency, resulting in bone loss.

[0089] Treatment: Ginger-separated moxibustion is applied to the Governor Vessel, and the Governor Vessel moxibustion powder is sprinkled on the skin of the back (Example 5). Ginger-separated moxibustion is carried out each time for 50 minutes. After several sessions of moxibustion, from not feeling obvious in the early stage to having a feeling of heat wandering during the moxibustion in the later stage, there is a numb feeling in the hands and legs, and the hunched part of the back becomes significantly flatter, and the whole person moves more neatly.

[0090] (3) Yuan XX, female, 15 years old

[0091] Symptoms of discomfort: Sinusitis for many years, manifested as persistent nasal congestion, headache, with more severe nasal congestion in the morning and a feeling of being unable to blow out completely. The disease is caused by exogenous pathogenic toxins, excessive heat in the liver and gallbladder steaming upward due to dampness and heat, stagnating in the nose, and is related to congenital deficiency, acquired malnutrition, and deficiency of the lungs, spleen, and kidneys.

[0092] Treatment: Ginger-separated moxibustion is applied to the Governor Vessel to disperse pathogenic toxins, warm and tonify the extraordinary meridians, promote blood circulation and remove blood stasis, dredge the collaterals and expel toxins. The Governor Vessel moxibustion powder is sprinkled on the skin of the back (Example 6), and ginger-separated moxibustion is carried out each time for 50 minutes. After the first moxibustion, the nose is ventilated, the nasal congestion in the morning is significantly reduced, and the headache is also relieved. In the later stage, local moxibustion is continuously combined.

[0093] (4) Sun XX, female, 44 years old

[0094] Symptoms of discomfort: Amenorrhea for 6 months, coldness in the lower abdomen, and constipation. The syndrome belongs to weakness of the spleen and stomach, qi stagnation and blood stasis, and deficiency of the liver and kidneys.

[0095] Treatment: Ginger-separated moxibustion is applied to the Governor Vessel to strengthen the healthy qi and consolidate the root, warm yang and dispel cold, regulate qi and blood, so that qi and blood become stronger day by day and the meridians are unobstructed. The Governor Vessel powder in the Governor Vessel moxibustion (Example 1) plays an important role in the moxibustion effect. After 4 sessions of Governor Vessel moxibustion, menstruation comes, and the constipation symptom is relieved. In the later stage, local moxibustion is continuously combined to restore the normal physiological functions of the body.

[0096] (5) Wang X, female, 47 years old

[0097] Symptoms of discomfort: amenorrhea for 6 months, pain in the knees of the left and right legs. Pain in the left lumbar region. The syndrome belongs to deficiency of kidney essence and the liver failing to store blood

[0098] Treatment: Select acupoints, moxibustion on the Governor Vessel. Apply Governor Vessel powder on the back skin (Example 2), moxibustion on the Governor Vessel with ginger slices in between, for 50 minutes. During the moxibustion process, the heat sensation conducts from top to bottom. The heat sensation in the right leg and both feet is obvious, while that in the left leg is not obvious. Usually, the pain in the left leg is severe. After one moxibustion session, the menstruation becomes normal. Moxibustion is performed once every 15 days. After 5 times, the pain in the left leg is relieved and the pain in the right leg disappears. The complexion of the whole person improves a lot, and moxibustion is continued later for consolidation.

[0099] As described above, the basic principle, main features and advantages of the present invention are preferably described. The above embodiments and the description are only for describing the preferred embodiments of the present invention. The present invention is not limited by the above embodiments. Without departing from the spirit and scope of the present invention, various changes and improvements made by those of ordinary skill in the art to the technical solutions of the present invention shall fall within the protection scope determined by the present invention.

Claims

1. A Du Meridian powder, characterized in that: The Du channel powder is composed of the following powdered components: ginseng, coptis root, Qiannianjian, Zhui Di Feng, sulfur, iron club, peach kernel, safflower, dalbergia odorifera, costusroot, radix pieris, spatholobi, myrrh, atractylodes, clematis, millet blood vine, red vine, dragon of the mountain, dragon of the river, wormwood leaf, barbata scabra, heather leaf and liquorice; Any component in the Du Meridian powder can be processed or not processed to form powder.

2. The Du Meridian powder according to claim 1, characterized in that The Du Meridian powder is composed of four layers of powdered components from top to bottom; The first layer is composed of the following powdered components: ginseng, coptis root, Qiannianjian, Zhui Di Feng, sulfur, iron club, peach kernel, safflower and dalbergia; The second layer is composed of the following powdered components: costusroot, radix spatholobi, radix striatae, myrrh, and atractylodes; The third layer is composed of the following powdered components: Clematis chinensis, Millettia reticulata, Red vine, Rhizoma Cyperi and Rhizoma Cyperi; The fourth layer is composed of the following powdered components: mugwort leaves, bark scutellaria, heather leaves and liquorice.

3. The Du Meridian powder according to claim 1, characterized in that: The Du channel powder is composed of the following powdered components in parts by weight: 50-70 parts of ginseng, 10-30 parts of coptis root, 10-30 parts of qiannianjian, 10-30 parts of zhuidifeng, 10-30 parts of sulfur, 10-30 parts of iron club, 10-30 parts of peach kernel, 20-40 parts of safflower, 10-20 parts of dalbergia odorifera, 10-20 parts of costusroot, 20-40 parts of radix spatholobi, 20-40 parts of lycopodii herba, 20-40 parts of myrrh, 90-110 parts of atractylodes, 20-40 parts of clematis, 40-60 parts of millettia reticulata, 50-70 parts of red vine, 40-60 parts of cyperus rotundus, 40-60 parts of cyperus rotundus, 90-110 parts of wormwood, 40-60 parts of scutellaria barbata, 40-60 parts of photinia serrulata leaves and 10-30 parts of liquorice.

4. The Du Meridian powder according to claim 3, characterized in that: The Du channel powder is composed of the following powdered components in parts by weight: 60 parts of ginseng, 20 parts of coptis root, 20 parts of millennium jian, 20 parts of zhuidifeng, 20 parts of sulfur, 20 parts of iron club, 20 parts of peach kernel, 30 parts of safflower, 15 parts of dalbergia odorifera, 15 parts of costus root, 30 parts of radix schoenii tuberculatae, 30 parts of lycopodii herba, 30 parts of myrrh, 100 parts of atractylodes, 30 parts of clematis, 50 parts of millettia reticulata, 60 parts of red vine, 50 parts of scutellaria baicalensis, 50 parts of scutellaria baicalensis, 100 parts of wormwood, 50 parts of scutellaria barbata, 50 parts of photinia serrulata and 20 parts of licorice.

5. A method for preparing the Du Meridian powder according to any one of claims 1 to 4, characterized in that: include: Ginseng and liquorice are dried and made into powder, and barbata scabra and heather leaves are washed and made into powder; The Du channel powder is prepared by grinding coptis root, Qiannianjian, Zhuidifeng, sulfur, Tiebangchui, peach kernel, safflower, Dalbergia odorifera, costusroot, radix polyphyllae, spatholobi, myrrh, atractylodes, clematis, Millettia reticulata, scutellaria baicalensis, Rhizoma Cyperi and wormwood into powder, and all the components are sealed and stored for at least 7 days to obtain the Du channel powder.

6. The method for preparing Du Meridian powder according to claim 5, characterized in that: Mix all the components and store them in sealed containers.

7. The method for preparing Du Meridian powder according to claim 5, characterized in that: Mix ginseng, coptis root, Qiannianjian, Zhui Di Feng, sulfur, iron club, peach kernel, safflower and dalbergia odorifera and seal them for storage; Mix costusroot, radix spatholobi, herba striatae, myrrha and atractylodes and seal them for storage; Mix Clematis chinensis, Millettia reticulata, Rhizoma Coptidis, Rhizoma Dioscoreae and Rhizoma Dioscoreae and seal them for storage; Mix mugwort leaves, bark stalks, heather leaves and licorice and seal them for storage.

8. Use of the Du Meridian powder according to any one of claims 1 to 4 in the preparation of a medicament for Du Meridian moxibustion.

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