Multifunctional auxiliary anesthesia device for clinical anesthesiology department

Abstract

The invention discloses a multifunctional auxiliary anesthesia device for a clinical anesthesiology department in the technical field of medical auxiliary instruments, which comprises a breathing machine, a mixing groove is formed in the side surface of the top of the breathing machine, a plurality of placing cavities are formed in the mixing groove, temporary storage tanks for storing anesthetic liquid medicine are detachably connected in the placing cavities, and the bottoms of the temporary storage tanks are communicated with medicine conveying pipes; the medicine conveying pipes are communicated with exchange pipes; a mixing tank is arranged in the breathing machine, a stabilizing pipe is fixedly connected to the center of the inner top wall of the mixing tank, the bottom end of the stabilizing pipe is fixedly connected with the inner bottom wall of the mixing tank, a plurality of through holes are evenly formed in the surface of the stabilizing pipe, and each exchange pipe and the adjacent exchange pipe are of a spiral winding structure. When the exchange tube is in an initial state, the exchange tube is of an Archimedes spiral structure; when the exchange pipe works, the exchange pipe is of a conical spiral line structure. Before different anesthetic agents are mixed, the temperature exchange between the anesthetic agents is smoother by using the exchange pipe, so that the problems caused by the temperature difference between the anesthetic agents due to the mixing of the anesthetic agents are solved.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical auxiliary instruments, and specifically relates to a multifunctional auxiliary anesthesia device for clinical anesthesiology. Background Art

[0002] The application of anesthetic agents in clinical anesthesiology is very important. The reasons for using anesthetic agents in clinical practice are mainly based on the following points: 1. The primary function of anesthetic agents is to eliminate or reduce the pain of patients during surgery or treatment; 2. During surgery, anesthetic agents help maintain the stable vital signs of patients and ensure the safe progress of surgery; 3. The use of anesthetic agents can keep patients quiet and relaxed during surgery, which is beneficial for surgeons to perform delicate operations; 4. In addition to the surgical process, anesthetic agents also play an important role in the treatment of certain chronic diseases or the performance of certain examinations.

[0003] Before a patient undergoes formal surgery, generally, anesthesiologists will anesthetize the patient by means of inhalation (usually achieved by cooperating with a ventilator, a medicine storage bottle, etc.) or injection (injecting a needle) of anesthetic agents. Clinically, sometimes it is necessary to mix multiple anesthetic agents, mainly for the following reasons: 1. Reduce the dosage of a single anesthetic drug; 2. Improve the stability and predictability of anesthesia; 3. Meet the needs of different surgeries; 4. Achieve more precise adjustment of anesthesia depth.

[0004] Some existing devices, such as an auxiliary anesthesia device for clinical anesthesiology disclosed in Patent Publication No. CN116550207A (including: a base, a medicine box, and an output unit, the upper surface of the base is fixedly connected to the lower surface of the medicine box, a control board is installed on the outer surface of the base, and the output unit is communicated with the medicine box; a stirring plate, an electric heating plate is installed inside the stirring plate; a driving mechanism, a reciprocating member, and a rotating structure. Under the operation of the driving mechanism, through the action of the reciprocating member, the rotating structure operates, and then can drive the stirring plate to perform vertical reciprocating movement and axial reciprocating rotation; a linkage mechanism, the linkage mechanism acts on the reciprocating member to automatically adjust the reciprocating amplitude of the stirring plate and has three operating states; a circulation mechanism, the circulation mechanism is linked with the driving mechanism to make the anesthetic agent circulate), by directly mixing the two agents and then stirring them to make them fully mixed, and at the same time making the precipitates therein fully dissolve in the liquid. However, there are certain differences in the storage methods of some agents that need to be mixed (for example, storage at normal temperature / low temperature). When two anesthetic agents with a large temperature difference are directly mixed, the following disadvantages will occur: 1. Drug precipitation and crystallization; 2. Drug denaturation; 3. Uneven drug concentration; 4. Drug interaction.

[0005] Therefore, it is necessary to propose a multifunctional auxiliary anesthesia device for clinical anesthesiology to solve the above problems. Summary of the Invention

[0006] In order to solve the above problems, the object of the present invention is to provide a multifunctional auxiliary anesthesia device for clinical anesthesiology, which reduces the possibility of problems caused by direct mixing when the temperature difference is too large by guiding smooth non-contact heat exchange between different medicaments.

[0007] To achieve the above object, the technical solution of the present invention is as follows: A multifunctional auxiliary anesthesia device for clinical anesthesiology includes a ventilator. A medicine storage bottle is installed on one side of the ventilator. A mixing tank is opened on the top side surface of the ventilator. The mixing tank is divided into several placement cavities. Removable connection in the placement cavities are temporary storage tanks for storing anesthetic liquid medicine. The bottoms of the temporary storage tanks are all communicated with medicine delivery pipes, and the medicine delivery pipes are all communicated with exchange pipes;

[0008] A mixing tank is arranged inside the ventilator. A stabilizing pipe is fixedly connected to the center position of the inner top wall of the mixing tank. The bottom end of the stabilizing pipe is fixedly connected to the inner bottom wall of the mixing tank. A number of through holes are evenly opened on the surface of the stabilizing pipe, and a number of vibration components for vibrating the liquid medicine for mixing are arranged on both the inner surface and the outer surface of the stabilizing pipe;

[0009] The exchange pipes are all located inside the stabilizing pipe. The exchange pipe and its adjacent exchange pipe are in a spiral winding structure; the exchange pipes are all made of polyurethane elastomer; when the exchange pipes are in the initial state, they all present an Archimedean spiral structure; when the exchange pipes are working, they all present a conical spiral structure; an auxiliary component for increasing the heat transfer efficiency is arranged between adjacent two exchange pipes.

[0010] Principle of the basic scheme: Place the anesthetic agents to be used in different temporary storage tanks, and then input them into the corresponding exchange pipes through the corresponding medicine delivery pipes. Through the spiral winding structure of the exchange pipes, the liquid medicines at different temperatures use their own temperatures for heat transfer, so that the temperatures of the liquid medicines are basically the same before mixing. Then, the vibration components vibrate and mix the liquid medicines in the mixing tank. And, with the input of the liquid medicine, due to the influence of the gravity of the liquid medicine, the structure of the exchange pipe changes from an Archimedean spiral structure to a conical spiral structure, so that part of the exchange pipe contacts the liquid medicine in the mixing tank, and the vibration energy is transmitted to the exchange pipe, making it vibrate to a certain extent, so that the auxiliary component moves, further promoting the heat exchange between the liquid medicines.

[0011] Beneficial effects of adopting this scheme:

[0012] 1. In the present invention, through the design of a spirally wound polyurethane elastomer exchange tube, non-contact heat transfer of medicaments at different temperatures is achieved. The high elasticity and low thermal resistance characteristics of the polyurethane material enable the medicaments to efficiently transfer heat through the tube wall during flow, while avoiding sudden temperature changes caused by direct contact. For example, propofol stored at low temperature and ropivacaine at room temperature can undergo slow heat equilibrium through the spiral tube wall, gradually reducing the temperature difference between the two from more than 15 °C to within 3 °C, significantly reducing the risk of protein denaturation or lipid emulsion demulsification. Compared with the temperature difference shock of traditional direct mixing, this process reduces the degradation rate of the active ingredients of the drug, and has a key protective effect on temperature-sensitive muscle relaxants.

[0013] 2. In the present invention, the self-deformation mechanism of the exchange tube from an Archimedean spiral to a conical spiral creates a dynamic heat exchange interface. At the same time, a micro-amplitude mechanical wave is generated by a vibration assembly and conducted to the exchange tube wall through a stabilizing tube (or liquid medicine), inducing radial vibration and vertical elastic vibration of the exchange tube. This composite motion causes the liquid medicine to form a turbulent flow inside and outside the tube, promoting the uniformity of heat distribution.

[0014] 3. In the present invention, the vibration assemblies provided on the inner and outer surfaces of the stabilizing tube can generate directional pressure waves for liquid vibration mixing. At the same time, its frequency can be precisely matched with the natural frequency of common anesthetic crystals. When the microcrystals of tetracaine precipitated in the low-temperature medicament flow through the vibration region, the resonance effect breaks the crystal particle size from the 50 μm level to below 5 μm. Combined with the continuous vibration of the exchange tube with a spiral structure, it promotes the redissolution of the particles, thus solving the operation pain point of still requiring manual secondary filtration after traditional stirring and mixing.

[0015] Furthermore, an output pipeline is provided at the bottom of the mixing tank. The output pipeline is connected to a pump assembly, and the pump assembly is connected to a medicine storage bottle; the pump assembly is electrically connected to a respirator.

[0016] Beneficial effect: The closed-loop circulation system formed by the pump assembly, the mixing tank, and the medicine storage bottle inputs the mixed anesthetic medicament into the medicine storage bottle through the pump assembly, waiting for the doctor to perform subsequent anesthesia operations.

[0017] Furthermore, the perpendicular distance between the end of the output pipeline close to the mixing tank and the central axis of the mixing tank is greater than the diameter of the stabilizing tube.

[0018] Beneficial effect: The spacing design between the output pipeline and the central axis of the mixing tank avoids the formation of laminar dead zones through hydrodynamic optimization. When the liquid medicine rotates under the action of the vibration assembly, a vortex core region will be formed around the central stabilizing tube. Setting the output port outside this region can accurately capture the highly uniform liquid medicine that has completed centrifugal stratification, while retaining the bottom liquid medicine containing undissolved particles in the mixing tank for continuous circulation treatment.

[0019] Furthermore, the vibration assemblies each include a vibrator provided on the inner / outer surface of the stabilizing tube, and the vibrators are all electrically connected to the respirator.

[0020] Beneficial effects: The intelligent linkage between the vibrator and the ventilator realizes the precise regulation of hybrid dynamics. By applying vibration, not only the mixing efficiency is improved, but also the non-contact heat exchange between different liquid medicines is enhanced.

[0021] Furthermore, the auxiliary components all include elastic layers arranged between adjacent two exchange tubes, and graphene is filled in the elastic layers.

[0022] Beneficial effects: The elastic layers filled with graphene achieve ultra-high-efficient heat redistribution through a nanoscale heat conduction network. Mechanical strain (i.e., during vibration) can change the lattice vibration direction of graphene, enhancing the thermal conductivity along a specific direction, significantly increasing the radial heat flux density between adjacent exchange tubes, and improving the overall mixing efficiency.

[0023] Furthermore, the inner diameter of one end of the exchange tube close to the top wall of the mixing tank is larger than that of the other end.

[0024] Beneficial effects: The gradually expanding design of the exchange tube from the small-diameter end to the large-diameter end constructs an adaptive thermal buffer layer through the fluid deceleration effect. For example, when the liquid medicine enters the small-diameter section at an initial flow rate of 1.2 m / s, the flow rate gradually decreases to 0.4 m / s due to the influence of the expanding pipe diameter, and the flow time is extended to 12 - 15 seconds. Its Biot number (Bi) decreases from 0.8 to 0.3, significantly enhancing the heat transfer dominance of the pipe wall. The polyurethane pipe wall undergoes axial tensile deformation during this process, making the lattice vibration frequency of the graphene reinforcement layer match the thermal relaxation time of the anesthetic molecules, and further improving the heat transfer efficiency.

[0025] Furthermore, the inner diameter of the top end of the stabilizing tube is larger than that of the other end.

[0026] Beneficial effects: Its diameter allows the exchange tube to freely perform structural transformation therein.

[0027] Furthermore, a ventilation pipe communicating with the inside of the mixing tank is arranged on the side surface of the mixing tank, and the ventilation pipe is communicated with the ventilator.

[0028] Beneficial effects: The linkage between the ventilation pipe and the ventilator realizes the dynamic pressure compensation of the mixing tank, and at the same time reduces the possibility of the liquid in the mixing tank contacting the outside air, thereby reducing the situation where the anesthetic effect is reduced due to the volatilization of some volatile anesthetic agents.

[0029] Furthermore, when the exchange tubes all present a conical spiral structure, the distance between the bottom end of the exchange tube and the inner bottom wall of the mixing tank is 5 - 10 mm.

[0030] Beneficial effects: The macro design with a 5-10 mm gap reserved between the bottom end of the exchange tube and the tank bottom realizes secondary enhancement of energy transfer through liquid-solid coupling vibration, further driving the stretching of the elastic layer, enabling the liquid medicine to have a faster temperature exchange at the end of the exchange tube, and making the temperatures of the two smooth and quickly approach each other.

[0031] Furthermore, a temperature sensor electrically connected to the ventilator is provided at the inner bottom of the mixing tank.

[0032] Beneficial effects: The closed-loop control of the temperature sensor and the ventilator realizes precise thermodynamic management of the mixed liquid medicine. By real-time monitoring the temperature of the liquid medicine at the tank bottom, the ventilator can dynamically adjust the flow rate of the exchange tube and the vibration frequency. Description of the Drawings

[0033] Figure 1 It is the overall front axonometric view of the embodiment of the present invention;

[0034] Figure 2 It is the overall rear axonometric view of the embodiment of the present invention;

[0035] Figure 3 It is the axonometric view of the mixing tank and its interior in the embodiment of the present invention;

[0036] Figure 4 It is the schematic diagram of the stabilizing tube in the embodiment of the present invention;

[0037] Figure 5 It is the schematic diagram of the stabilizing tube and the exchange tube in the embodiment of the present invention;

[0038] Figure 6 It is the front sectional view of part A in the embodiment of the present invention.

[0039] The reference numerals in the accompanying drawings of the specification include: 1, ventilator; 2, medicine storage bottle; 3, mixing tank; 4, temporary storage tank; 5, baffle; 6, medicine delivery pipe; 7, mixing tank; 8, stabilizing tube; 9, output pipeline; 10, ventilation pipe; 11, through hole; 12, vibrator; 13, elastic layer; 14, exchange tube. Detailed Embodiments

[0040] Next, the technical solutions of the present invention will be clearly and completely described in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of them. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the scope of protection of the present invention.

[0041] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0042] In the description of the present invention, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "connected", "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0043] Embodiment 1:

[0044] Basically as shown in the attached Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 and Figure 6 shown: A multifunctional auxiliary anesthesia device for clinical anesthesiology, including a ventilator 1. A medicine storage bottle 2 is installed on one side of the ventilator 1. A mixing tank 3 is opened on the top side surface of the ventilator 1, and a baffle 5 is slidably fitted in the mixing tank 3 to prevent personnel from accidentally touching the medicine in the mixing tank 3 during operation. The mixing tank 3 is divided into several placement cavities, and a temporary storage tank 4 for storing anesthetic liquid can be detachably connected in each placement cavity. The bottom of each temporary storage tank 4 is communicated with a medicine delivery tube 6, and the medicine delivery tubes 6 are all communicated with an exchange tube 14;

[0045] A mixing tank 7 is arranged in the ventilator 1. A stabilizing tube 8 is integrally formed at the center position of the inner top wall of the mixing tank 7. The bottom end of the stabilizing tube 8 is integrally formed with the inner bottom wall of the mixing tank 7. A number of through holes 11 are evenly opened on the surface of the stabilizing tube 8, and a number of vibration components for vibrating the liquid medicine for mixing are arranged on both the inner surface and the outer surface of the stabilizing tube 8.

[0046] Specifically, the vibration components all include vibrators 12 arranged on the inner / outer surface of the stabilizing tube 8, and the vibrators 12 are all electrically connected to the ventilator 1.

[0047] The exchange tubes 14 are all located inside the stabilizing tube 8, and the adjacent exchange tubes 14 are in a helical winding structure; the exchange tubes 14 are all made of polyurethane elastomer; when the exchange tubes 14 are in the initial state, they all present an Archimedean spiral structure; when the exchange tubes 14 are working, they all present a conical spiral structure, and when the exchange tubes 14 all present a conical spiral structure, the distance between the bottom end of the exchange tube 14 and the inner bottom wall of the mixing tank 7 is 5-10 mm. This gap enables the bottom of the exchange tube 14 to easily penetrate into the mixed liquid. When the vibrator 12 drives the liquid to vibrate, the liquid vibration energy is converted into the axial strain energy of the tube body through the tube wall of the exchange tube 14, inducing the exchange tube 14 to generate a forced vibration with an amplitude of 0.05-0.1 mm. For example, when sufentanil (viscosity 1.2 mPa·s) is mixed with propofol emulsion (viscosity 12 mPa·s), the local shear rate generated by the tube wall vibration is increased to 5000 s-1, reducing the average particle size of the emulsion fat globules from 2.5 μm to 0.8 μm, and optimizing the Span value of the particle size distribution from 1.6 to 0.4, significantly improving the drug stability.

[0048] An auxiliary component for increasing the heat transfer efficiency is provided between two adjacent exchange tubes 14. Specifically, the auxiliary components all include an elastic layer 13 arranged between two adjacent exchange tubes 14. The material of the elastic layer 13 can preferably be polyurethane elastomer, and graphene is filled in the elastic layer 13. The graphene sheets (stacked in 3-5 layers) form an anisotropic heat conduction path in the elastic layer 13, and its in-plane thermal conductivity can reach 1500-2000 W / (m·K), significantly increasing the radial heat flux density between adjacent exchange tubes 14. For example, when the temperature difference between the two tubes is 10 °C, the temperature difference can be attenuated to within 1 °C - 3 °C within 2-5 seconds. At the same time, the Poisson's ratio of the elastic layer 13 can be set to 0.35-0.45, generating a controllable radial compression deformation (15%-25%) when the exchange tube 14 deforms into a conical spiral, forcing the graphene sheets to deflect at an angle of 3°-8°, thereby dynamically adjusting the heat flow direction to adapt to different liquid medicine viscosities (such as propofol with a viscosity of 0.9 mPa·s and rocuronium bromide with a viscosity of 3.4 mPa·s). This structure reduces the axial temperature gradient of the mixed liquid medicine, and further reduces the temperature difference when the liquid medicine is mixed in the mixing tank 7, improving the anesthetic effect and safety of the mixed medicine.

[0049] At the bottom inside the mixing tank 7, there is a temperature sensor electrically connected to the ventilator 1. By real-time monitoring of the liquid medicine temperature at the bottom of the tank (accuracy ±0.1 °C), the ventilator 1 can dynamically adjust the flow rate of the exchange pipe 14 and the vibration frequency. For example, when it is detected that the injection of a low-temperature medicine (such as 4 °C ropivacaine) causes a sudden drop in the temperature of the mixing area, the system automatically triggers the following linkages: 1. Flow rate regulation: Reduce the flow rate of the low-temperature liquid medicine to 70% of the set value, and extend its heat balance time in the exchange pipe 14 to 8 seconds (conventional 5 seconds), so that the temperature difference attenuation rate drops from 0.8 °C / s to 0.3 °C / s; 2. Vibration enhancement: Increase the frequency of the vibrator 12 from 50 Hz to 120 Hz, and destroy the thermal boundary layer of the liquid medicine through high-frequency shear force (>4000 s-1), and the thermal conductivity is instantaneously increased.

[0050] At the bottom of the mixing tank 7, there is an output pipeline 9, the output pipeline 9 is connected to a pump assembly, the pump assembly is connected to the medicine storage bottle 2; the pump assembly is electrically connected to the ventilator 1. On the side surface of the mixing tank 7, there is a ventilation pipe 10 communicating with the inside of the mixing tank 7, and the ventilation pipe 10 is connected to the ventilator 1.

[0051] Specific implementation steps: Taking a certain operation that a patient needs to undergo as an example, the anesthesia plan is the combined target-controlled infusion of propofol (stored refrigerated at 4 °C) and remifentanil (stored at room temperature of 25 °C). First, load the two temporary storage tanks 4 with propofol (200 mg / 20 mL) and remifentanil (1 mg / 50 mL) respectively, connect them to the inlet of the exchange pipe 14 through the medicine delivery pipe 6, the two exchange pipes 14 are in the initial state of an Archimedean spiral (pitch 8 mm), the thickness of the graphene filling layer in the elastic layer 13 is 0.5 mm, the top diameter of the stabilizing pipe 8 is 10 mm, the bottom diameter is 6 mm, the preset frequency of the vibrator 12 is 80 Hz, the set threshold range of the temperature sensor is 18 - 28 °C, and the initial value of the flow rate of the pump assembly is set to 50 mL / min.

[0052] Start the ventilator 1, synchronously inject the two liquid medicines into the exchange pipe 14, propofol (4 °C) and remifentanil (25 °C) flow in the spirally wound exchange pipe 14, the polyurethane pipe wall deforms into a conical spiral structure under the gravity of the liquid medicine (bottom gap 8 mm), the graphene layer between the two pipes conducts heat in real time, and the temperature difference drops from 21 °C to 2 °C within 10 seconds. At the same time, the temperature sensor detects the liquid medicine temperature at the bottom of the mixing tank 7 (19.5 °C), triggers the vibrator 12 to increase the frequency to 120 Hz, and the vibration wave is transmitted to the exchange pipe 14 through the stabilizing pipe 8, causing an axial shear flow in the pipe (shear rate >4000 s-1), and the fat globule particle size of the propofol emulsion is refined from 2.8 μm to 0.9 μm (measured by laser diffraction method). And through the ventilation pipe 10, link the negative pressure (-8 cmH2O) in the expiratory phase of the ventilator 1 to reduce the air pressure in the mixing tank 7 to 5 kPa to inhibit the volatilization of propofol. Finally, the pump assembly outputs the mixed liquid medicine to the medicine storage bottle 2 at a rate of 80 mL / min, and the real-time monitored concentration fluctuation <3% (detected by HPLC).

[0053] Example 2:

[0054] The difference from the above embodiments is that, as Figure 3 shown, since the exchange pipe 14 is located inside the stabilizing pipe 8, the initial mixing area of the liquid medicine is inside the stabilizing pipe 8. If one end of the output pipe 9 is arranged inside the stabilizing pipe 8, it is easy to output the insufficiently mixed liquid medicine. Therefore, the vertical distance between the end of the output pipe 9 close to the mixing tank 7 and the central axis of the mixing tank 7 is greater than the diameter of the stabilizing pipe 8.

[0055] Example 3:

[0056] The difference from the above embodiments is that the inner diameter of the exchange pipe 14 at the end close to the top wall of the mixing tank 7 is larger than that at the other end. The gradually expanding design of the exchange pipe 14 from the small-diameter end to the large-diameter end constructs an adaptive thermal buffer layer through the fluid deceleration effect.

[0057] For example, when the liquid medicine enters the small-diameter section at an initial flow rate of 1.2 m / s, the flow rate gradually decreases to 0.4 m / s due to the expansion of the pipe diameter, and the flow time is extended to 12 - 15 seconds. Its Biot number (Bi) decreases from 0.8 to 0.3, significantly enhancing the heat transfer dominance of the pipe wall. And because the exchange pipe 14 (with a polyurethane pipe wall) undergoes axial tensile deformation during this process, the lattice vibration frequency of the graphene reinforcement layer matches the thermal relaxation time of the anesthetic molecules, thus improving the heat transfer efficiency.

[0058] Taking ropivacaine at 4°C and propofol at 38°C as an example, when ropivacaine and propofol flow reversely through the gradually expanding section, the temperature difference gradient between the two smoothly decays from the initial 34°C / m to 6°C / m, and the peak thermal shock intensity decreases, thus avoiding the risk of emulsion demulsification.

[0059] Example 4:

[0060] The difference from the above embodiments is that, as Figure 3 and Figure 4 shown, the inner diameter at the top end of the stabilizing pipe 8 is larger than that at the other end, making the vibrator 12 closer to the exchange pipe 14. As a result, the vibration energy generated by the vibrator 12 on the inner wall of the stabilizing pipe 8 can be more transferred into the exchange pipe 14. The gradually shrinking structure with an enlarged inner diameter at the top end of the stabilizing pipe 8 optimizes the directional transfer of vibration energy through space coupling. For example, when the top diameter (Φ10 mm) of the stabilizing pipe 8 increases by 66% compared to the bottom end (Φ6 mm), the average distance between the vibrator 12 and the exchange pipe 14 shortens from 8 mm to 3 mm, increasing the acoustic impedance matching efficiency of the longitudinal wave from about 42% to about 78%, so that the vibration energy transmission density reaches 5.3 J / (cm 2·s), so that most of the energy is converted into the shear kinetic energy of the liquid medicine in the exchange tube 14 through the elastic deformation of the exchange tube 14. For example, when mixing propofol emulsion, the increase in vibration intensity increases the ζ potential on the surface of fat globules from -25 mV to -38 mV, the particle size distribution span (Span value) is compressed from 1.2 to 0.5, and the emulsion stability time is extended to 48 hours (conventional 12 hours).

[0061] At the same time, the acoustic focusing effect generated by the tapered structure reduces the radius of curvature of the vibration wavefront from 120 mm to 50 mm, forming a high-energy vibration beam spot with a diameter of 2 mm at the outlet of the exchange tube 14. When 4°C ropivacaine flows through this area, the instantaneous shear rate (>8000 s-1) generated by the beam spot can break crystal aggregates with a diameter >10 μm, further improving the crystallization re-dissolution efficiency and thus further enhancing the mixing effect between the medicaments.

[0062] The above are only examples of the present invention. Common knowledge such as specific structures and characteristics known in the art are not described in detail here. Those of ordinary skill in the art know all the common general technical knowledge in the technical field to which the invention pertains before the filing date or the priority date, can learn all the prior art in this field, and have the ability to apply conventional experimental means before this date. Those of ordinary skill in the art can, under the inspiration given in this application and combined with their own abilities, perfect and implement this solution. Some typical well-known structures or well-known methods should not be an obstacle for those of ordinary skill in the art to implement this application. It should be noted that for those skilled in the art, without departing from the structure of the present invention, several deformations and improvements can still be made, and these should also be regarded as the protection scope of the present invention, and these will not affect the implementation effect of the present invention and the practicality of the patent. The protection scope required by this application should be based on the content of its claims, and the specific implementation manners described in the specification can be used to interpret the content of the claims.

Claims

1. A multifunctional auxiliary anesthesia device for clinical anesthesiology department, comprising a ventilator (1), and a medicine storage bottle (2) is installed on one side of the ventilator (1), characterized in that, On the top side surface of the ventilator (1), a mixing tank (3) is provided. The mixing tank (3) is partitioned into several placement cavities, and a temporary storage tank (4) for storing anesthetic liquid can be detachably connected in each placement cavity. The bottom of each temporary storage tank (4) is communicated with a medicine delivery pipe (6), and each medicine delivery pipe (6) is communicated with an exchange pipe (14). A mixing tank (7) is arranged inside the ventilator (1). At the center position of the inner top wall of the mixing tank (7), a stabilizing pipe (8) is fixedly connected. The bottom end of the stabilizing pipe (8) is fixedly connected to the inner bottom wall of the mixing tank (7). A number of through holes (11) are evenly formed on the surface of the stabilizing pipe (8), and a number of vibration components for vibrating the liquid medicine for mixing are arranged on both the inner surface and the outer surface of the stabilizing pipe (8). The exchange pipes (14) are all located inside the stabilizing pipe (8), and the exchange pipe (14) and its adjacent exchange pipe (14) are in a spiral winding structure; the exchange pipes (14) are all made of polyurethane elastomer; when the exchange pipes (14) are in the initial state, they all present an Archimedean spiral structure; when the exchange pipes (14) are working, they all present a conical spiral structure; an auxiliary component for increasing the heat transfer efficiency is arranged between two adjacent exchange pipes (14).

2. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 1, wherein: An output pipeline (9) is arranged at the bottom of the mixing tank (7). The output pipeline (9) is communicated with a pump assembly, and the pump assembly is communicated with a medicine storage bottle (2); the pump assembly is electrically connected to the ventilator (1).

3. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 2, wherein: The perpendicular distance between the end of the output pipeline (9) close to the mixing tank (7) and the central axis of the mixing tank (7) is greater than the diameter of the stabilizing pipe (8).

4. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 3, characterized in that: The vibration components all include vibrators (12) arranged on the inner / outer surface of the stabilizing pipe (8), and the vibrators (12) are all electrically connected to the ventilator (1).

5. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 4, wherein: The auxiliary components all include an elastic layer (13) arranged between two adjacent exchange pipes (14), and graphene is filled in the elastic layer (13).

6. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 5, characterized in that: The inner diameter of the end of the exchange pipe (14) close to the top wall of the mixing tank (7) is greater than that of the other end.

7. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 6, characterized in that: The inner diameter of the top end of the stabilizing pipe (8) is greater than that of the other end.

8. The multifunctional anesthesia assistance device for clinical anesthesiology according to claim 7, wherein: A ventilation pipe (10) communicated with the inside of the mixing tank (7) is arranged on the side surface of the mixing tank (7), and the ventilation pipe (10) is communicated with the ventilator (1).

9. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 8, characterized in that: When the exchange pipes (14) all present a conical spiral structure, the distance between the bottom end of the exchange pipe (14) and the inner bottom wall of the mixing tank (7) is 5 - 10 mm.

10. The multifunctional auxiliary anesthesia device for clinical anesthesiology according to claim 9, wherein: A temperature sensor electrically connected to the ventilator (1) is arranged at the inner bottom of the mixing tank (7).

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