Rib bone plate, rib bone plate preparation method, and bone plate base preparation method

Abstract

The present invention provides a rib plate and a method for preparing a rib plate, and also provides a method for preparing a plate base. The rib plate is used to connect a broken left bone and a broken right bone. The rib plate includes a connecting portion, a columnar portion, a fixing portion, and a plurality of abutting whiskers. The columnar portion is connected to the first end of the connecting portion, and the fixing portion is connected to the second end of the connecting portion. The abutting whiskers are fixed to the side wall of the columnar portion. The connecting portion is located in the bone marrow cavity of the broken left bone and the broken right bone, the abutting whiskers abut the inner wall of the bone marrow cavity of the broken left bone, and there is a gap between the columnar portion and the inner wall of the bone marrow cavity, and the fixing portion is connected to the broken right bone. The present invention provides the abutting whiskers so that the rib plate of the present invention is not prone to large deformation, and is not prone to lateral displacement of the fractured rib end due to human breathing. At the same time, the surgical incision of the rib plate is small.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a rib bone fracture plate, a method for preparing the rib bone fracture plate, and a method for preparing a bone fracture plate matrix. Background Art

[0002] When a rib is fractured, a plate is often used to connect the broken bones together.

[0003] Currently, there are two main types of bone fixation plates used clinically: external fixation and intramedullary fixation. External fixation plates are installed on the outer surface of the bone, while intramedullary fixation plates are implanted in the bone marrow cavity for fixation. From a biomechanical perspective, intramedullary fixation plates are closer to the mechanical neutral axis of the bone. When responding to mechanical loads such as bending and torsion, they are subject to significantly less stress than external fixation plates placed on the bone surface. This design advantage makes the intramedullary fixation system perform better in terms of mechanical stability.

[0004] However, existing intramedullary fixation plates mostly use a fixation method that fixes the plate at both ends. First, the intramedullary nail is implanted into the bone marrow cavity using an intramedullary nail fixation method, and then the two ends of the plate are fixed to the two ends of the bone crack with fixing nails. However, when the existing intramedullary fixation plate is used on the ribs, the ribs will also move when the human body breathes. Due to the gap between the plate body and the inner wall of the bone marrow cavity, the plate body will also move in the radial direction of the bone marrow cavity, and the plate body is prone to large deformation, which eventually leads to lateral displacement of the rib fracture end. At the same time, the existing intramedullary fixation plate requires fixing with fixing nails at both ends, so the surgical wound is large. Summary of the Invention

[0005] In response to the problems existing in the above-mentioned prior art, the present invention discloses a rib bone plate, a method for preparing a rib bone plate, and a method for preparing a bone plate matrix. The fractured ends of the ribs are not prone to lateral displacement, and the surgical wound is smaller.

[0006] The purpose of the present invention is achieved through the following technical solutions:

[0007] The present invention provides a rib bone plate for connecting a broken left bone and a broken right bone, comprising a connecting portion, a columnar portion, a fixing portion and a plurality of abutting whiskers; the columnar portion is connected to a first end of the connecting portion, and the fixing portion is connected to a second end of the connecting portion; the abutting whiskers are fixed on the side wall of the columnar portion; the connecting portion is located in the bone marrow cavity of the broken left bone and the broken right bone, the abutting whiskers abut against the inner wall of the bone marrow cavity of the broken left bone, and there is a gap between the columnar portion and the inner wall of the bone marrow cavity, and the fixing portion is connected to the broken right bone.

[0008] Furthermore, it also includes a plurality of space-retaining whiskers arranged on the columnar portion, the space-retaining whiskers are all arranged on the side of the supporting whiskers away from the connecting portion, and there is a gap between the space-retaining whiskers and the inner wall of the bone marrow cavity; a gap is provided between each of the space-retaining whiskers for accommodating bone fragments in the bone marrow cavity.

[0009] Furthermore, a gap is provided between each of the abutting tendons for accommodating bone debris in the medullary cavity.

[0010] Furthermore, the resisting whiskers include a hydrogel layer, which forms the outer surface of the resisting whiskers. After the hydrogel layer absorbs body fluid and swells, the contact area between the resisting whiskers and the inner wall of the bone marrow cavity increases.

[0011] Furthermore, the connecting portion, the columnar portion, the fixing portion and the abutting member are all made of degradable materials.

[0012] Furthermore, a guide portion for opening a passage is provided at one end of the columnar portion away from the connecting portion.

[0013] Furthermore, a surgical hole is provided on the side wall of the broken right bone, the columnar portion, the abutting whiskers and the connecting portion pass through the surgical hole and enter the bone marrow cavity, and the fixing portion is fixed on the outer wall of the broken right bone.

[0014] Furthermore, one end of the abutting whisker and the yielding whisker are both connected to the side wall of the columnar portion, and the other end of the abutting whisker abuts the inner wall of the bone marrow cavity of the broken left bone; the abutting whisker and the yielding whisker are both inclined toward one side of the connecting portion.

[0015] Furthermore, the connecting portion, the columnar portion and the fixing portion are all provided with reinforcing ribs, and the reinforcing ribs are covered with a silk protein layer; the reinforcing ribs include magnesium wires, PCL wires and / or PCLA wires.

[0016] Furthermore, the PCL wire and / or the PCLA wire are wound around the magnesium wire and woven to form the reinforcing rib.

[0017] Furthermore, at least two reinforcing ribs are provided; the reinforcing ribs are arranged in parallel, or the reinforcing ribs are arranged crosswise.

[0018] Furthermore, the supporting whiskers also include a silk protein core, and the hydrogel layer covers the silk protein core.

[0019] The present invention also provides a method for preparing a rib bone plate, which is used to prepare the rib bone plate having a silk protein core as the support, comprising the following steps:

[0020] Step 1: providing a bone plate base, wherein the bone plate base comprises a columnar portion, a connecting portion, and a fixing portion connected in sequence;

[0021] Step 2: mixing the silk protein solution and the silver nanowire solution to form a first mixed solution;

[0022] Step 3, using the first mixed solution to prepare a silk protein core, wherein one end of the silk protein core is connected to the columnar portion;

[0023] Step 4, mixing the silk protein solution, gelatin, polypyrrole monomer, ferric chloride, glycerol and chitosan to form a second mixed solution;

[0024] Step five: immersing the silk protein core in the second mixed liquid, and forming a hydrogel layer on the silk protein core through an electrochemical reaction, thereby obtaining the resisting whiskers.

[0025] In addition, the present invention provides a method for preparing a bone plate matrix, which is used to prepare the bone plate matrix, comprising the following steps:

[0026] Step 1: PCL wire and / or PCLA wire are mixed and braided with magnesium wire to form reinforcing ribs;

[0027] Step 2: placing the reinforcing rib into a pouring container, and fixing both ends of the reinforcing rib to the side walls of the pouring container;

[0028] Step 3: injecting the silk protein solution into the casting container, immersing the reinforcing ribs in the silk protein solution, and obtaining a bone plate blank after the casting is completed;

[0029] Step 4: Perform a subtractive manufacturing process on the bone plate blank to form the bone plate base.

[0030] Compared with the prior art, the beneficial effect of the present invention is that: by setting the abutting whiskers, one end of the bone plate is equivalent to being movably connected to the medullary cavity. During the reciprocating motion of the ribs caused by human breathing, the bone plate reciprocates along the axis of the medullary cavity in the medullary cavity, and the rib bone plate of the present invention is not easy to produce large deformation. And because the abutting whiskers abut the inner wall of the medullary cavity, it is equivalent to there being no gap between one end of the rib bone plate and the inner wall of the medullary cavity. Therefore, the rib bone plate of the present invention is not easy to cause lateral displacement of the fractured end of the rib due to human breathing. In addition, the rib bone plate of the present invention is only fixedly connected to the rib at one end, and the surgical incision is small. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 This is a schematic diagram of a traditional intramedullary fixation plate in the medullary cavity of a fractured rib;

[0032] Figure 2 is a schematic diagram of the rib bone plate of the present invention in the medullary cavity of a fractured rib;

[0033] Figure 3 is a three-dimensional diagram of a rib bone plate of the present invention;

[0034] Figure 4 is a top view of the rib bone plate of the present invention;

[0035] Figure 5 This is a front view of the rib bone fracture plate of the present invention;

[0036] Figure 6 is a three-dimensional view of the bone plate base of the present invention;

[0037] Figure 7 is a perspective view of a reinforcing rib of the present invention;

[0038] Figure 8 is a schematic diagram of the reinforcing rib of the present invention in a pouring container;

[0039] Figure 9 is a schematic diagram of the parallel arrangement of reinforcing ribs in the present invention;

[0040] Figure 10 It is a schematic diagram of the cross-arranged reinforcing ribs in the present invention.

[0041] In the picture:

[0042] 1a-fractured left bone; 1b-fractured right bone; 2-connecting part; 3-columnar part; 4-fixing part; 5-supporting whiskers; 6-displacing whiskers; 7-guide part; 8-reinforcement ribs; 8a-magnesium wire; 8b-PCL wire; 8c-PCLA wire; 9-casting container; 10-bone plate body; 11-through screw; 12-fixing screw. DETAILED DESCRIPTION

[0043] The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0044] In the description of the present invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are intended solely to facilitate and simplify the description of the present invention. They are not intended to indicate or imply that the devices or components referred to must have, be constructed, or operate in a specific orientation, and therefore should not be construed as limitations on the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0045] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be internal communication between two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0046] Traditional intramedullary fixation plates Figure 1 As shown, the plate body 10 is implanted in the bone marrow cavity of the fractured rib, and the bones on the left and right sides of the crack of the fractured rib are defined as the broken left bone 1a and the broken right bone 1b respectively. The first end of the plate body 10 is located in the bone marrow cavity of the broken left bone 1a, and the first end of the plate body 10 is fixed to the broken left bone 1a by a through screw 11. The second end of the plate body 10 is located in the bone marrow cavity of the broken right bone 1b, and the second end of the plate body 10 is fixed to the broken right bone 1b by a fixing screw 12. Figure 1 As can be seen in the figure, in order to facilitate the implantation of the bone plate body 10 into the bone marrow cavity, there is a gap between the first end of the bone plate body 10 and the inner wall of the rib bone marrow cavity. Therefore, the traditional intramedullary fixation bone plate has the following defects:

[0047] First, when the human body breathes, the ribs will reciprocate due to the expansion and contraction of the chest cavity, and the bone plate body 10 will also reciprocate accordingly. The long-term reciprocating movement of the bone plate body 10 can easily cause the bone plate body 10 to deform.

[0048] Secondly, due to the gap between the plate body 10 and the inner wall of the medullary cavity, during the breathing process of the human body, as the ribs move back and forth, the plate body 10 will also move in the radial direction of the medullary cavity, eventually causing the rib fracture end to shift laterally, such as Figure 1 As shown, there is a dislocation between the broken left bone 1a and the broken right bone 1b.

[0049] Third, because the first end of the plate body 10 is fixed to the fractured left bone 1a via the through screw 11, and the second end of the plate body 10 is fixed to the fractured right bone 1b via the fixation screw 12, at least two incisions are required during implantation of the plate body 10 into the rib, one for securing the through screw 11 and the other for securing the fixation screw 12, resulting in a relatively large surgical incision.

[0050] In view of the defects of the above-mentioned traditional intramedullary fixation bone plate, the present invention discloses a rib bone plate, which adopts the intramedullary fixation method, such as Figure 2As shown, it is used to connect the broken left bone 1a and the broken right bone 1b on the ribs.

[0051] like Figures 3 to 5 As shown, the rib bone plate of the present invention includes a connecting portion 2, a columnar portion 3, a fixing portion 4, and a plurality of abutting whiskers 5. The columnar portion 3 is connected to the first end of the connecting portion 2, and the fixing portion 4 is connected to the second end of the connecting portion 2, that is, the columnar portion 3, the connecting portion 2, and the fixing portion 4 are connected in sequence along the same straight line. The abutting whiskers 5 are fixed to the side wall of the columnar portion 3, and the abutting whiskers 5 and the columnar portion 3 form a shape similar to a feather duster. The connecting portion 2 is a flat, long plate with high strength and rigidity, and is used to connect the broken left bone 1a and the broken right bone 1b.

[0052] like Figure 2 As shown, when the rib bone plate of the present invention needs to be implanted on a fractured rib. A surgical hole connecting to the medullary cavity is opened on the broken right bone 1b, and then the columnar portion 3 is driven together with the abutting whiskers 5 to enter the surgical hole. At this time, the abutting whiskers 5 have abutted the inner wall of the medullary cavity of the broken right bone 1b. The columnar portion 3 is pushed toward the broken left bone 1a, and the connecting portion 2 also enters the medullary cavity of the broken right bone 1b. The columnar portion 3 is continued to be pushed together with the abutting whiskers 5 toward the broken left bone 1a. When the columnar portion 3 enters the medullary cavity of the broken left bone 1a, the abutting whiskers 5 abut the inner wall of the medullary cavity of the broken left bone 1a. The columnar portion 3 is continued to be pushed together with the abutting whiskers 5 toward the broken left bone 1a until the connecting portion 2 enters the medullary cavity of the broken left bone 1a. At this time, a part of the connecting portion 2 is still located in the medullary cavity of the broken right bone 1b.

[0053] like Figure 2 As shown, after the connecting portion 2 is located in the medullary cavity of the broken left bone 1a and the broken right bone 1b, the columnar portion 3 is located in the medullary cavity of the broken left bone 1a, and the abutting whiskers 5 abut the inner wall of the medullary cavity of the broken left bone 1a. The friction between each abutting whisker 5 and the inner wall of the medullary cavity makes it difficult for the abutting whiskers 5 to move, thereby making it difficult for the columnar portion 3 to move. Due to the presence of the abutting whiskers 5, there is a gap between the columnar portion 3 and the inner wall of the medullary cavity. Compared to the abutting whiskers 5, the harder columnar portion 3 will not abut the inner wall of the medullary cavity, so that the columnar portion 3 will not be caused by the reciprocating movement of the ribs due to human breathing, thereby causing the columnar portion 3 to rub back and forth in the medullary cavity. Subsequently, the fixing portion 4 is connected to the broken right bone 1b, and the implantation of the rib bone plate of the present invention is completed.

[0054] The rib bone fracture plate of the present invention has the following advantages:

[0055] First, when the human body breathes, the ribs reciprocate due to the expansion and contraction of the chest cavity. Because the abutting whiskers 5 are relatively soft and non-rigidly connected to the inner wall of the medullary cavity of the fractured left bone 1a, even if the ribs reciprocate, the columnar portion 3 only reciprocates along the axis of the medullary cavity within the fractured left bone 1a, minimizing the deformation of the connecting portion 2 that connects the fractured ribs.

[0056] Secondly, because the supporting force 5 is against the inner wall of the bone marrow cavity of the broken left bone 1a, there is no gap between the rib bone plate of the present invention and the inner wall of the bone marrow cavity of the broken left bone 1a. Therefore, the rib bone plate of the present invention is not easy to move with the breathing of the human body, resulting in the occurrence of the following between the broken left bone 1a and the broken right bone 1b: Figure 1 Misalignment shown.

[0057] Thirdly, because the rib bone plate of the present invention needs to be connected to the fractured rib only at the fixing portion 4, the surgical incision of the rib bone plate of the present invention is smaller than that of conventional intramedullary fixation bone plates which require at least two fixing points.

[0058] The rib plate of the present invention has various technical features, such as the material and arrangement of the abutting whiskers 5 , that can be implemented in various ways. Below, a detailed description of each of these technical features, including the material of the abutting whiskers 5 , will be given of one embodiment. This embodiment will be referred to as the present embodiment. Other implementations of these features, such as the material of the abutting whiskers 5 , are referred to as other embodiments, which are briefly described below.

[0059] In this embodiment, if Figure 2 and Figure 3 As shown, the rib bone plate of the present invention also includes a plurality of displacement whiskers 6 arranged on the columnar portion 3. The displacement whiskers 6 are elastic. Each displacement whisker 6 is arranged on the side of the abutting whisker 5 away from the connecting portion 2. The abutting whisker 5 and the displacement whisker 6 can be fixed on the columnar portion 3 at one end, and the length of the displacement whisker 6 is shorter than the length of the abutting whisker 5. When the rib bone plate of the present invention is implanted into a fractured rib, there is a gap between each displacement whisker 6 and the inner wall of the bone marrow cavity of the broken left bone 1a. At the same time, a gap is provided between each displacement whisker 6 for accommodating bone debris in the bone marrow cavity, such as Figure 2 As shown, each of the clearance whiskers 6 can be disposed around the axis of the columnar portion 3 , and each of the clearance whiskers 6 is arranged in an array, so that bone debris can be stuck in the gaps between the clearance whiskers 6 .

[0060] In this embodiment, if Figure 2 and Figure 3As shown, after a rib fracture, some bone debris from the fracture will fall into the medullary cavity. Since the abutting whiskers 5 already abut the inner wall of the medullary cavity of the fractured right bone 1b when entering it, the abutting whiskers 5 may push bone debris from the medullary cavity of the fractured right bone 1b through the rib fracture crack and out of the medullary cavity as they move along with the columnar portion 3 toward the fractured left bone 1a. This can cause bone debris to fall into the chest cavity, potentially damaging internal organs. However, due to the placement of the reciprocating whiskers 6, the reciprocating whiskers 6 never come into contact with the medullary cavity during their movement. Because the medullary cavity contains other substances such as red bone marrow, bone debris often adheres to the sidewalls of the medullary cavity. When the abutting whiskers 5 come into contact with bone debris that has fallen into the medullary cavity, they cause the debris to dislodge from the sidewalls. The dislodged bone debris then becomes lodged in the spaces between the reciprocating whiskers 6. As the retaining whiskers 5 continue to move toward the fractured left bone 1a, the repositioning whiskers 6, along with the bone fragments, move into the medullary cavity of the fractured left bone 1a. Therefore, the provision of the repositioning whiskers 6 in the present invention significantly reduces the possibility of bone fragments falling into the chest cavity. In other embodiments, if an X-ray examination reveals that the medullary cavity is relatively clean and free of bone fragments, the repositioning whiskers 6 may be omitted.

[0061] In this embodiment, if Figure 2 and Figure 3 As shown, each of the abutting whiskers 5 is also provided with a gap for accommodating bone debris in the medullary cavity. Each of the abutting whiskers 5 is also arranged around the axis of the columnar portion 3, and the abutting whiskers 5 are arranged in an array. Therefore, when the abutting whiskers 5 move in the medullary cavity of the broken right bone 1b, some bone debris may also be stuck in the gap between the abutting whiskers 5, reducing the possibility of bone debris falling into the chest cavity. At the same time, in this embodiment, due to the provision of the yield whiskers 6, even if some bone debris does not get stuck in the gap between the abutting whiskers 5, it can still fall into the gap between the yield whiskers 6. In other embodiments, when an X-ray examination shows that the medullary cavity is relatively clean and free of bone debris, in addition to not providing the yield whiskers 6, the abutting whiskers 5 can also be arranged in a dispersed or dense arrangement, that is, the abutting whiskers 5 can adopt a gap that is much larger than the maximum length of the bone debris and a gap that is much smaller than the minimum length of the bone debris. In other embodiments, either one of the gaps between the yielding whiskers 6 for accommodating bone debris in the medullary cavity or the gaps between the supporting whiskers 5 for accommodating bone debris in the medullary cavity can be selected, but the effect is not as good as setting both.

[0062] In this embodiment, if Figure 2As shown, the supporting whiskers 5 include a hydrogel layer, which forms the outer surface of the supporting whiskers 5. Hydrogel is a type of extremely hydrophilic three-dimensional network structure gel that swells rapidly when exposed to water. When the rib bone plate of the present invention is in the process of implantation, the hydrogel layer will not expand immediately because the implantation process takes a short time. However, after the rib bone plate of the present invention is implanted, the body fluid in the bone marrow cavity contains moisture, and this moisture is in contact with the hydrogel layer located at the supporting whiskers 5 for a long time. The hydrogel layer absorbs the moisture in the body fluid and gradually expands, thereby increasing the contact area between the supporting whiskers 5 and the inner wall of the bone marrow cavity, thereby increasing the friction between the supporting whiskers 5 and the inner wall of the bone marrow cavity located at the broken left bone 1a, and further making the connection of the rib bone plate of the present invention more stable. In other embodiments, the supporting whiskers 5 can also be made entirely of silk protein, so that the supporting whiskers 5 have better flexibility.

[0063] In this embodiment, if Figure 2 As shown, the support whiskers 5 also include a silk protein core, and the hydrogel layer covers the silk protein core. Since hydrogel has the disadvantages of low strength and poor toughness, in order to prevent the support whiskers 5 from entering the bone marrow cavity and being squeezed and broken during the implantation of the rib bone fracture plate of the present invention, it is necessary to set a silk protein core inside the hydrogel layer to play a supporting role. Silk protein has good mechanical properties and physical and chemical properties, such as good flexibility and tensile strength. During the preparation of the support whiskers 5, the silk protein core is first fixed on the columnar portion 3, and then the hydrogel layer is coated on the outside of the silk protein core. The yield whiskers 6 can be made only of silk protein and cannot have a hydrogel component, so as to avoid the expansion of the yield whiskers 6 affecting the accommodation of bone fragments. In other embodiments, in order to reduce the preparation cost of the support whiskers 5, the support whiskers 5 can be completely composed of hydrogel, but in this embodiment, the support whiskers 5 are prone to breakage.

[0064] In this embodiment, if Figure 2 and Figure 3 As shown, one end of the abutting whiskers 5 and the giving way whiskers 6 are both connected to the side wall of the columnar portion 3, and the other end of the abutting whiskers 5 abuts the inner wall of the bone marrow cavity of the broken left bone 1a. The abutting whiskers 5 and the giving way whiskers 6 are both inclined toward one side of the connecting portion 2. Therefore, each abutting whisker 5 and each giving way whisker 6 together form an arrow-shaped structure, which facilitates the movement of the abutting whiskers 5 and the giving way whiskers 6 in the bone marrow cavity. In other embodiments, if the giving way whiskers 6 are not provided, and there is no need to provide a gap between each abutting whisker 5 for accommodating bone fragments, the middle part of each abutting whisker 5 can also be fixed on the columnar portion 3, and the fixing points of each abutting whisker 5 on the columnar portion 3 are located on the same radial cross-section of the columnar portion 3, and the fixing points of each abutting whisker 5 on the columnar portion 3 are arranged at equal intervals, and both ends of each abutting whisker 5 are used to abut the inner wall of the bone marrow cavity.

[0065] In this embodiment, if Figure 2 and Figure 3As shown, a guide portion 7 for clearing a passage is provided at one end of the columnar portion 3 away from the connecting portion 2. The cross-sectional area of ​​the guide portion 7 gradually decreases in a direction away from the connecting portion 2, i.e., the tip of the guide portion 7 is positioned in a direction away from the connecting portion 2. The present invention utilizes the provision of the guide portion 7 to allow the connecting portion 2 to move within the medullary cavity while the connecting portion 2 moves within the medullary cavity, thereby clearing a passage for the connecting portion 2. In other embodiments, the guide portion 7 may be provided when there is no bone debris or other debris within the medullary cavity.

[0066] In this embodiment, if Figure 2 As shown, the surgical hole is provided on the side wall of the fractured right bone 1b. The guide portion 7, columnar portion 3, retracting whiskers 6, abutting whiskers 5, and connecting portion 2 pass through the surgical hole and enter the medullary cavity of the fractured right bone 1b. After the abutting whiskers 5 abut the inner wall of the medullary cavity of the fractured left bone 1a, the fixing portion 4 is fixed to the outer wall of the fractured right bone 1b. Specifically, the fixing portion 4 is provided in close contact with the outer wall of the fractured right bone 1b, and the fixing point of the fixing portion 4 is located near the surgical hole. By fixing the fixing portion 4 to the outer wall of the fractured right bone 1b, the present invention facilitates surgical operation. Furthermore, since the surgical hole is located near the fixing point of the fixing portion 4, the surgical incision can be smaller. Furthermore, since the fixing portion 4 is in close contact with the outer wall of the fractured right bone 1b, the rib plate of the present invention has no gap between the ribs at both ends, making it less likely for the ribs to be misaligned due to breathing. In other embodiments, the fixing portion 4 can also be fixed to the inner wall of the medullary cavity of the fractured right bone 1b. In this way, the rib plate is completely located within the medullary cavity, but securing the fixing portion 4 is difficult.

[0067] In this embodiment, if Figure 2 As shown, the connecting portion 2, the columnar portion 3, the fixing portion 4 and the supporting whiskers 5 are all made of degradable materials. Similarly, the yield whiskers 6 can also be made of degradable materials, that is, the rib plates of the present invention are all made of degradable materials. Conventional rib plates are usually made of metal materials that are not easily degraded, so after the fracture is healed, the conventional rib plates need to be taken out again to avoid blockage of the bone marrow cavity. Because the rib plates of the present invention are all made of degradable materials, the rib plates can automatically degrade during the healing process of the rib fracture, and there is no need for a second operation to remove the rib plates. In this embodiment, the degradable material can be a degradable metal material such as silk protein and magnesium metal.

[0068] In this embodiment, if Figure 6As shown, the connecting portion 2, the columnar portion 3, the fixing portion 4 and the guide portion 7 are all made of a degradable material in one piece. In some embodiments without the guide portion 7, the connecting portion 2, the columnar portion 3 and the fixing portion 4 are made of a degradable material in one piece. Regardless of whether there is a guide portion 7, the present invention refers to the structure consisting of the connecting portion 2, the columnar portion 3, the fixing portion 4 and the guide portion 7, or the structure consisting of the connecting portion 2, the columnar portion 3 and the fixing portion 4 as a bone plate matrix. The bone plate matrix is ​​in the shape of a long strip, so when the bone plate matrix enters the bone marrow cavity, it will not block the bone marrow cavity, and the nutrients in the bone marrow cavity still have a large space to flow freely.

[0069] In this embodiment, if Figure 6 and Figure 7 As shown, the plate base is composed of reinforcing ribs 8 and a silk protein layer covering the reinforcing ribs 8. The connecting portion 2, columnar portion 3, fixing portion 4, and guide portion 7 all have reinforcing ribs. In some embodiments without the guide portion 7, the connecting portion 2, columnar portion 3, and fixing portion 4 all have reinforcing ribs. The reinforcing ribs 8 include magnesium filaments 8a, and also include PCL filaments 8b and / or PCLA filaments 8c. The reinforcing ribs 8 serve to enhance the strength of the plate base. PCL stands for polylactic acid, and PCLA stands for polylactic acid copolymer. Both PCL and PCLA produce acid upon degradation. Magnesium metal, on the other hand, produces base upon degradation. Therefore, through acid-base neutralization, degradation of the plate base does not produce side effects on the human body. Silk protein is a natural, biodegradable, and harmless high-molecular-weight fibrous protein. Therefore, by providing the reinforcing ribs 8 and the silk protein layer, the plate base is degradable while maintaining its strength. Meanwhile, due to the setting of magnesium wire 8a, therefore rib bone plate of the present invention develops under CT irradiation, is convenient to the position that doctor clearly understands bone plate.In other embodiments, bone plate matrix also can all be made of silk protein, but the intensity of bone plate matrix is ​​difficult to guarantee, need to design the shape of bone plate matrix, as the radial cross section of design bone plate matrix is ​​triangular, to promote the intensity of bone plate matrix, but the intensity of bone plate matrix under this embodiment is not as good as present embodiment.Simultaneously, the bone plate matrix only made of silk protein can't develop under CT irradiation, therefore in bone plate matrix preparation process, need to add as developer such as iohexol, iopamidol in silk protein solution, and developer can damage kidney.

[0070] In this embodiment, if Figure 7 As shown, PCL wire 8b and / or PCLA wire 8c are wound around magnesium wire 8a and woven to form reinforcing rib 8. Figure 7In the embodiment, magnesium wire 8a is located in the center, while PCL wire 8b and PCLA wire 8c are located on either side of magnesium wire 8a. By arranging the reinforcing rib 8 using braided magnesium wire 8a and other materials, the present invention ensures more effective acid-base neutralization during the degradation of the reinforcing rib 8. In other embodiments, to reduce manufacturing costs and simplify the braiding steps of the reinforcing rib 8, the magnesium wire 8a, PCL wire 8b, and PCLA wire can also be arranged parallel to each other.

[0071] With respect to the structure of the bone plate base in this embodiment, the present invention further discloses a method for preparing the bone plate base, which specifically comprises the following steps:

[0072] Step 1, such as Figure 7 As shown, PCL wires 8b and / or PCLA wires 8c are mixed and woven with magnesium wires 8a to form the reinforcing ribs 8.

[0073] Step 2, such as Figure 8 As shown, the reinforcing rib 8 is bent to form a Z-shaped shape. The reinforcing rib 8 is then placed in a pouring container 9. The pouring container 9 is a box-shaped container with an opening on one side. The two opposite side walls of the pouring container 9 are provided with receiving holes for accommodating the ends of the reinforcing rib 8. During the process of placing the reinforcing rib 8 into the pouring container 9, the two ends of the reinforcing rib 8 are respectively fixed in the receiving holes located on the side walls of the pouring container 9. In order to ensure the strength of the bone plate base, at least two reinforcing ribs 8 are provided, and each reinforcing rib 8 can be as shown in the following example. Figure 9 In the manner shown, the ribs 8 are arranged in parallel in the casting container 9; or as shown in FIG. Figure 10 In the manner shown, the reinforcing ribs 8 and the casting containers 9 are arranged crosswise.

[0074] Step three, such as Figure 8 As shown, the silk protein solution is injected into the casting container 9, and each reinforcing rib 8 is immersed in the silk protein solution. After the casting is completed, the bone plate blank is obtained.

[0075] Step 4: The bone plate blank is processed by a subtractive manufacturing process to form Figure 6 The bone plate base shown is in a Z-like shape.

[0076] In addition, in this embodiment, after the bone plate base is obtained through the casting process and the subtractive manufacturing process, it is necessary to prepare the abutting bead 5 and the relief bead 6 on the columnar portion 3 before the rib bone plate of the present invention can be finally manufactured. The abutting bead 5 and the relief bead 6 have the same structure, and the method of preparing the abutting bead 5 is used as an example to explain in detail below. Specifically:

[0077] The present invention provides a method for preparing a rib bone plate, comprising the following steps:

[0078] Step 1: Provide a prepared bone plate base.

[0079] Step 2: Mix the silk protein solution and the nano silver wire solution to form a first mixed solution. Specifically, the nano silver wire solution is added to the silk protein solution, the concentration of the nano silver wire solution is between 0.5-2 mg / mL, the concentration of the silk protein solution is between 5 and 10 mg / mL, and the ratio of the nano silver wire solution to the silk protein solution is approximately 1 to 5 to 1 to 20. Since the nano silver wires are in the form of filaments, the nano silver wire solution and the silk protein solution are easier to mix. Stir the mixture of the silk protein solution and the nano silver wire solution in a clockwise direction. The stirring speed is set to 300-500 rpm. This stirring speed can ensure that the nano silver wires are evenly dispersed in the silk protein solution while not destroying the nano silver wires in the mixed solution or generating too many unnecessary bubbles in the mixed solution due to excessive stirring speed. After 2 to 3 hours of continuous stirring, the nano silver wires are fully diffused in the silk protein solution, and the first mixed solution is obtained.

[0080] Step 3: Use the first mixed solution to prepare a silk protein core, one end of which is connected to the columnar portion 3. Specifically, a 3D printing method is used to additively manufacture a silk protein core with a diameter of 0.5 mm on the side wall of the columnar portion 3 using the first mixed solution. The angle between the axis of the silk protein core and the axis of the columnar portion 3 is 35° to 45°.

[0081] Step 4, mixing the silk protein solution, gelatin, polypyrrole monomer, ferric chloride, glycerol and chitosan to form a second mixed solution;

[0082] Step five, immerse the silk protein core in the second mixed solution, and form a hydrogel layer on the silk protein core through an electrochemical reaction, thereby obtaining the resisting whiskers 5. In detail, when the silk protein core is immersed in the second mixed solution, the silk protein core and the platinum sheet are placed in the second mixed solution. Because the silk protein core contains nano silver wires, it can be used as an electrode for the electrochemical reaction like the platinum sheet. Subsequently, the silk protein core and the platinum sheet are energized to carry out an electrochemical reaction, and the DC voltage of the energization is set to 1.5-3V, the current density of the energization is set to 0.1-0.5mA / cm², and the energization time is set to 10-30 minutes. During the electrochemical reaction, the negatively charged silk protein and polypyrrole monomer in the second mixed solution migrate to and enrich the silk protein core as the anode, and then the iron ions in the ferric chloride trigger the polymerization of the polypyrrole monomer on the surface of the silk protein core. At the same time, the silk protein and gelatin are cross-linked through hydrogen bond hydrophobic interaction, thereby forming a hydrogel layer on the surface of the silk protein core. At the same time, since the silk protein core contains filamentous nano-silver wires, during the electrochemical reaction, it is easier for the negatively charged silk protein and polypyrrole monomers in the second mixed solution to gather on the surface of the silk protein core.

[0083] In summary, the present invention utilizes the support whiskers 5 to minimize surgical incisions. The rib plate of the present invention exhibits minimal deformation during breathing, and the fractured left bone 1a and right bone 1b are less likely to misalign. Furthermore, the provision of the repositioning whiskers 6 significantly reduces the likelihood of bone debris entering the thoracic cavity. The provision of gaps between the support whiskers 5 to accommodate bone debris within the medullary cavity also reduces the likelihood of bone debris entering the thoracic cavity. The provision of a hydrogel layer further enhances the stability of the rib plate connection. Furthermore, the support whiskers 5 contain a silk protein core, ensuring excellent mechanical and physical and chemical properties. The support whiskers 5 and repositioning whiskers 6 are both inclined toward the connecting portion 2, facilitating their movement within the medullary cavity. The provision of the guide portion 7 facilitates movement of the connecting portion 2 within the medullary cavity. Furthermore, the securing portion 4 to the outer wall of the fractured right bone 1b facilitates surgical operation. By making the rib plates from biodegradable materials, the rib plates can be removed without a second surgery. The reinforcement ribs 8 and silk protein layer ensure that the plate base is biodegradable while maintaining its strength. The position of the plate base can be clearly determined under CT scans. Furthermore, by making the reinforcement ribs 8 woven from magnesium wire 8a, for example, the acid-base neutralization process is more complete during the degradation of the reinforcement ribs 8.

[0084] It should be emphasized that the above are only preferred embodiments of the present invention and do not limit the present invention in any form. Any simple modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A rib bone plate for connecting a broken left bone (1a) and a broken right bone (1b), characterized in that: It comprises a connecting portion (2), a columnar portion (3), a fixing portion (4) and a plurality of supporting whiskers (5); The columnar portion (3) is connected to the first end of the connecting portion (2), and the fixing portion (4) is connected to the second end of the connecting portion (2); The abutting member (5) is fixed on the side wall of the columnar portion (3); The connecting portion (2) is located in the bone marrow cavity of the broken left bone (1a) and the broken right bone (1b), the abutting bar (5) abuts against the inner wall of the bone marrow cavity of the broken left bone (1a), and a gap exists between the columnar portion (3) and the inner wall of the bone marrow cavity, and the fixing portion (4) is connected to the broken right bone (1b); It also includes a plurality of paving whiskers (6) arranged on the columnar portion (3), the paving whiskers (6) are all arranged on the side of the abutting whisker (5) away from the connecting portion (2), and there is a gap between the paving whiskers (6) and the inner wall of the bone marrow cavity; a gap is provided between each of the paving whiskers (6) for accommodating bone debris in the bone marrow cavity; The abutting whiskers (5) include a hydrogel layer, and the hydrogel layer forms the outer surface of the abutting whiskers (5); after the hydrogel layer absorbs body fluid and expands, the contact area between the abutting whiskers (5) and the inner wall of the bone marrow cavity increases; The supporting whiskers (5) further comprise a silk protein core, and the hydrogel layer covers the silk protein core.

2. The rib bone plate according to claim 1, characterized in that: A gap is provided between each of the abutting bars (5) for accommodating bone debris in the bone marrow cavity.

3. The rib bone plate according to claim 1, characterized in that: The connecting portion (2), the columnar portion (3), the fixing portion (4) and the abutting whiskers (5) are all made of degradable materials.

4. The rib bone fracture plate according to claim 1, characterized in that: The columnar portion (3) is provided with a guide portion (7) for opening a passage at one end away from the connecting portion (2).

5. The rib bone plate according to claim 1, characterized in that: A surgical hole is provided on the side wall of the broken right bone (1b); the columnar portion (3), the abutting whiskers (5) and the connecting portion (2) pass through the surgical hole and enter the bone marrow cavity; the fixing portion (4) is fixed on the outer wall of the broken right bone (1b).

6. The rib bone fracture plate according to claim 1, characterized in that: One end of the abutting whisker (5) and the one end of the giving way whisker (6) are both connected to the side wall of the columnar portion (3), and the other end of the abutting whisker (5) abuts the inner wall of the bone marrow cavity of the broken left bone (1a); the abutting whisker (5) and the one end of the giving way whisker (6) are both inclined toward one side of the connecting portion (2).

7. The rib bone fracture plate according to claim 3, characterized in that: Reinforcing ribs (8) are provided in the connecting portion (2), the columnar portion (3) and the fixing portion (4), and the reinforcing ribs (8) are coated with a silk protein layer; the reinforcing ribs (8) include magnesium wires (8a), PCL wires (8b) and / or PCLA wires (8c).

8. The rib bone plate according to claim 7, characterized in that: The PCL wire (8b) and / or the PCLA wire (8c) are wound around the magnesium wire (8a) and woven to form the reinforcing rib (8).

9. The rib bone fracture plate according to claim 8, characterized in that: At least two reinforcing ribs (8) are provided; the reinforcing ribs (8) are arranged in parallel, or the reinforcing ribs (8) are arranged crosswise.

10. A method for preparing a rib bone plate, used for preparing the rib bone plate according to claim 8, characterized in that: The following steps are involved: Step 1: providing a bone plate base, wherein the bone plate base comprises a columnar portion (3), a connecting portion (2), and a fixing portion (4) connected in sequence; Step 2: mixing the silk protein solution and the silver nanowire solution to form a first mixed solution; Step 3, using the first mixed solution to prepare the silk protein core, one end of the silk protein core is connected to the columnar portion (3); Step 4, mixing the silk protein solution, gelatin, polypyrrole monomer, ferric chloride, glycerol and chitosan to form a second mixed solution; Step five: immersing the silk protein core in the second mixed solution, and forming a hydrogel layer on the silk protein core through an electrochemical reaction, thereby obtaining the resisting whiskers (5).

11. A method for preparing a bone plate matrix, characterized in that: Used for preparing the bone plate matrix described in claim 10, The following steps are included: Step 1: PCL wire (8b) and / or PCLA wire (8c) are mixed and braided with magnesium wire (8a) to form a reinforcing rib (8); Step 2: placing the reinforcing rib (8) into a pouring container (9), and fixing both ends of the reinforcing rib (8) to the side walls of the pouring container (9); Step three, injecting the silk protein solution into the casting container (9), immersing the reinforcing rib (8) in the silk protein solution, and obtaining a bone plate blank after the casting is completed; Step 4: Perform a subtractive manufacturing process on the bone plate blank to form the bone plate base.

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