Traditional Chinese medicine aqueous solution for treating skin defects and facilitating healing as well as preparation method and application of traditional Chinese medicine aqueous solution

Abstract

The invention discloses a traditional Chinese medicine aqueous solution for treating skin defects and facilitating healing and a preparation method and application thereof.The traditional Chinese medicine aqueous solution is prepared from, by weight, 12-18 parts of honeysuckle, 12-18 parts of dandelion, 12-18 parts of herba violae, 8-12 parts of rheum officinale, 8-12 parts of curcuma zedoary, 8-12 parts of rhizoma sparganii, 8-12 parts of frankincense, 8-12 parts of myrrh, 8-12 parts of sanguisorba officinalis and 8-12 parts of astragalus membranaceus. According to the formula principle of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, removing necrotic tissue, promoting granulation and promoting wound healing, all the medicines are compatible to jointly achieve the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, removing necrotic tissue, promoting granulation and promoting wound healing, the healing process of skin defects such as bedsores, car accidents, burns and scalds, great saphenous vein ulcer and the like is effectively accelerated, scar formation is reduced, and wound infection is avoided.

Description

Technical Field

[0001] The invention belongs to traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine aqueous solution for treating skin defects and facilitating healing, and a preparation method and application thereof. Background Art

[0002] There are many causes of skin defects. Bedsores are often caused by long-term bed rest, poor blood circulation, malnutrition of the skin, and damage and infection due to pressure and friction. Car accidents are caused by direct external force acting on the skin, causing tissue damage. Burns and scalds are caused by high-temperature substances contacting the skin, causing skin damage. Varicose vein ulcers are mostly caused by blood stasis, meridian blockage, and loss of skin warmth.

[0003] Although modern medicine has a variety of treatments, it still has shortcomings in promoting rapid skin healing, reducing scar formation and avoiding side effects. Traditional Chinese medicine has unique advantages in these aspects. Therefore, it is of great significance to develop and improve a Chinese medicine decoction that has wide applicability, significant efficacy, safety and no side effects. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine aqueous solution to address the shortcomings of existing drugs for treating skin defects in terms of efficacy, safety and scope of application, which can effectively promote the healing of various skin defects, relieve patients' pain, reduce scar formation, avoid wound infection, improve treatment effects, and have few side effects.

[0005] The technical scheme of the present invention is: a Chinese medicinal water preparation for treating skin defects and facilitating healing. The Chinese medicinal components in the Chinese medicinal water preparation include the following raw materials by weight: 12-18 parts of honeysuckle, 12-18 parts of dandelions, 12-18 parts of Viola yedoensis, 8-12 parts of rhubarb, 8-12 parts of Curcuma, 8-12 parts of Trigonella ternate, 8-12 parts of frankincense, 8-12 parts of myrrh, 8-12 parts of Sanguisorba officinalis and 8-12 parts of Astragalus.

[0006] The preparation method of the above-mentioned Chinese medicine aqueous solution comprises the following steps: S1: Accurately weigh honeysuckle, dandelion, plantain, rhubarb, zedoary, trifoliate green, frankincense, myrrh, sanguisorba officinalis, and astragalus, and check their appearance and smell to ensure that they are not deteriorated or infested by insects; S2: Put the weighed medicinal materials into a casserole or ceramic container, add clean water at a mass ratio of the Chinese medicine composition raw materials to water of 1:4-6, gently stir to fully immerse the medicinal materials, and soak for 30-60 minutes; S3: After soaking, first use high heat to quickly boil the water, then use low heat to keep it at a slight boil and continue to boil for 30-40 minutes; during the boiling process, stir it from time to time to prevent the herbs from sticking to the pot; S4: After the decoction is completed, the medicinal soup is filtered into a clean container to obtain the first decoction, and the medicinal residue is left in the original container; S5: Add clear water to the medicinal residues obtained in S4. The amount of clear water is half of the amount of water added for the first time. Perform the second decoction according to the decocting method in step S3 for 20 - 30 minutes; filter to obtain the second decocted medicinal juice. S6: Combine the medicinal juices obtained from the two decoctions in one container and stir evenly to make the concentration of the medicinal juice consistent. S7: Slowly concentrate the combined medicinal juice over a low heat until the water content is 50%, cool it to room temperature, sterilize it, and then package it according to the requirements of sub-packaging to obtain the traditional Chinese medicine aqueous solution.

[0007] Among them, the traditional Chinese medicine aqueous solution is packaged into an external spray.

[0008] Among them, the traditional Chinese medicine aqueous solution is applicable to skin defect problems caused by bedsore, traffic accident injury, burn and scald, and varicose ulcer of great saphenous vein.

[0009] The efficacy of the traditional Chinese medicine components in the above traditional Chinese medicine aqueous solution is as follows: Honeysuckle: Honeysuckle is cold in nature, sweet in taste, and belongs to the lung, heart, and stomach meridians. It has the effects of clearing heat and detoxifying, and dispersing wind and heat. In the treatment of skin defects, honeysuckle can clear the heat toxin at the wound, prevent and control infections, especially suitable for the cases of burn and scald, and traffic accident injury that are prone to infection, reduce the inflammatory reaction, and promote wound healing.

[0010] Dandelion: Dandelion is cold in nature, bitter and sweet in taste, and belongs to the liver and stomach meridians. It has the effects of clearing heat and detoxifying, dissipating swelling and nodules, and promoting diuresis and relieving stranguria. Dandelion can effectively clear the heat toxin around the wound, and has good anti-inflammatory and swelling-reducing effects on various skin defects accompanied by inflammation and swelling, and promotes the repair of damaged skin tissues.

[0011] Viola philippica: Viola philippica is cold in nature, bitter in taste, and belongs to the heart and liver meridians. It can clear heat and detoxify, cool blood and reduce swelling. When combined with honeysuckle and dandelion, it enhances the effects of clearing heat and detoxifying, and dissipating swelling and nodules, and has a significant relieving effect on the symptoms of redness, swelling, heat, and pain at the skin defect site, especially suitable for the diseases caused by the accumulation of heat toxin in burn and scald.

[0012] Rhubarb: Rhubarb is cold in nature, bitter in taste, and belongs to the spleen, stomach, large intestine, lung, pericardium, and liver meridians. It has the effects of purging and reducing accumulation, clearing heat and purging fire, cooling blood and detoxifying, and promoting blood circulation to remove blood stasis. Rhubarb promotes the excretion of blood stasis and heat toxin in the body in the prescription, regulates the gastrointestinal function, enhances the excretion ability of the body, is beneficial to the healing of skin defects, and at the same time its effect of promoting blood circulation to remove blood stasis helps to improve the local blood circulation and promote the growth of new tissues.

[0013] Curcuma zedoaria: Curcuma zedoaria is warm in nature, bitter and pungent in taste, and belongs to the liver and spleen meridians. It can promote blood circulation to break up stasis, promote qi movement and relieve pain, and eliminate stasis and masses. Curcuma zedoaria effectively promotes the blood circulation at the skin defect site, dissipates stasis masses, and has a significant therapeutic effect on skin defect diseases caused by qi stagnation and blood stasis, such as varicose ulcer of great saphenous vein, and accelerates the wound healing.

[0014] Rhizoma Sparganii: Rhizoma Sparganii is neutral in nature, bitter and pungent in taste, and belongs to the liver and spleen meridians. It functions to break blood and promote qi movement, eliminate accumulation and relieve pain. Acting synergistically with Rhizoma Curcumae, it enhances the power of promoting blood circulation to remove blood stasis, promoting qi movement and eliminating accumulation, accelerates the repair process of damaged tissues, reduces scar formation, and is applicable to skin defects caused by various reasons accompanied by stasis swelling and pain.

[0015] Olibanum: Olibanum is warm in nature, pungent and bitter in taste, and belongs to the heart, liver and spleen meridians. It has the effects of promoting blood circulation to relieve pain, dissipating swelling and promoting granulation. Olibanum can promote local qi and blood circulation, disperse stasis swelling and pain, and at the same time stimulate the growth of new tissues, which plays an important role in relieving the pain caused by skin defects and promoting healing, especially showing significant curative effects in bedsore and car accident injury diseases.

[0016] Myrrh: Myrrh is neutral in nature, pungent and bitter in taste, and belongs to the heart, liver and spleen meridians. It functions to disperse stasis and relieve pain, dissipate swelling and promote granulation. Acting synergistically with Olibanum, it enhances the power of promoting blood circulation to remove blood stasis, dissipating swelling and relieving pain, accelerates the repair process of damaged tissues, reduces scar formation, and is applicable to skin defects caused by various reasons accompanied by stasis swelling and pain.

[0017] Radix Sanguisorbae: Radix Sanguisorbae is cold in nature, bitter and sour in taste, and belongs to the liver and spleen meridians. It has the effects of cooling blood to stop bleeding, detoxifying and astringing sores. Radix Sanguisorbae can effectively remove heat toxin from the skin defect site, promote wound healing and tissue repair. At the same time, its effect of cooling blood to stop bleeding has a good hemostatic effect on the bleeding symptoms of various skin defects, especially applicable to burn and scald, and varicose ulcer of great saphenous vein accompanied by bleeding.

[0018] Radix Astragali: Radix Astragali is slightly warm in nature, sweet in taste, and belongs to the lung and spleen meridians. It has the effects of tonifying qi and lifting yang, benefiting qi and strengthening the superficial resistance, expelling toxins and promoting granulation, etc. Radix Astragali greatly tonifies qi and blood, provides sufficient vital qi support for skin repair, enhances the body's immunity, and promotes wound healing, especially applicable to skin defect diseases caused by long-term illness or qi and blood deficiency, such as bedsore, etc.

[0019] Compared with the prior art, the beneficial effects of the present invention are as follows: 1. Wide applicability: The present invention is based on the syndrome differentiation and treatment of skin defect diseases in traditional Chinese medicine, and comprehensively combines a variety of traditional Chinese medicines with the effects of promoting blood circulation to remove blood stasis, clearing heat and detoxifying, dissipating swelling and relieving pain, promoting granulation and astringing sores, tonifying qi and nourishing blood. Each drug acts synergistically to comprehensively improve qi and blood circulation, promote the delivery of nutrients to damaged skin tissues, accelerate the shedding of necrotic tissues and the growth of new tissues. Clinical practice has proved that after using the aqueous solution of the present invention, the healing time of patients with skin defects caused by different etiologies is significantly shortened, and the symptoms are significantly improved.

[0020] 2. Safe and non-toxic side effects: The traditional Chinese medicine raw materials in the aqueous solution of the present invention are all natural herbs, which are widely sourced and have been verified by long-term clinical practice, with high safety. The toxic and side effects on the human body are extremely small, especially suitable for long-term ill, patients with weak physical functions and various skin defect patients for long-term use, and will not cause obvious burden on liver and kidney functions.

[0021] 3. Promote tissue repair and reduce scar formation: The combined action of various traditional Chinese medicine components can not only promote cell proliferation and tissue regeneration at the skin defect site, but also regulate the local immune function and microenvironment. For example, frankincense and myrrh, which have the effects of detumescence and promoting granulation, stimulate the activity of fibroblasts, promote the synthesis of collagen, enable the new tissue to grow more healthily and orderly, and thus reduce the formation of scar tissue. In the late stage of wound healing, it can help the skin recover elasticity and luster, improve the healing quality, and reduce the impact of skin defects on the patient's body and appearance.

[0022] 4. Significant curative effect: Flos Lonicerae, Herba Taraxaci, and Herba Violae have the effects of clearing heat and detoxifying, antibacterial and anti-inflammatory, and are the monarch drugs; Rheum palmatum purges heat and promotes defecation, cools blood and detoxifies, Rhizoma Curcumae and Rhizoma Sparganii promote qi and break blood stasis, eliminate accumulation and relieve pain, frankincense and myrrh promote blood circulation and remove blood stasis, reduce swelling and relieve pain, and are the ministerial drugs; Radix Sanguisorba cools blood and stops bleeding, detoxifies and astringes sores, Astragalus membranaceus replenishes qi and supports detoxification, promotes granulation and astringes sores, and is the adjuvant drug. The monarch, ministerial, and adjuvant drugs synergistically enhance the effect dialectically and improve the curative effect. Specific implementation mode

[0023] The following further illustrates the technical solution of the present invention in combination with specific embodiments, but it should not be construed as a limitation to the technical solution.

[0024] Example 1: Prepare a traditional Chinese medicine aqueous solution for promoting healing of skin defects according to the following steps S1: Accurately weigh Flos Lonicerae, Herba Taraxaci, Herba Violae, Rheum palmatum, Rhizoma Curcumae, Rhizoma Sparganii, frankincense, myrrh, Radix Sanguisorba, and Astragalus membranaceus, and check their appearance and smell to ensure no deterioration or insect damage; the raw materials of each traditional Chinese medicine component are calculated by weight as follows: 12 parts of Flos Lonicerae, 12 parts of Herba Taraxaci, 12 parts of Herba Violae, 8 parts of Rheum palmatum, 8 parts of Rhizoma Curcumae, 8 parts of Rhizoma Sparganii, 8 parts of frankincense, 8 parts of myrrh, 8 parts of Radix Sanguisorba, and 8 parts of Astragalus membranaceus; S2: Put the weighed medicinal materials into a casserole or ceramic container, add clear water according to the mass ratio of the traditional Chinese medicine composition raw materials to water of 1:4, gently stir to completely immerse the medicinal materials, and soak for 30 minutes; S3: After soaking, first quickly bring the water to a boil with strong fire, and then change to slow fire to keep it boiling gently and continue to decoct for 30 minutes; during the decocting process, stir appropriately to prevent the medicinal materials from sticking to the pot; S4: After the decocting is completed, filter the decoction into a clean container to obtain the first decocted medicinal juice, and leave the medicinal residues in the original container; S5: Add clear water to the medicinal residues in S4, and the clear water is half of the first added water volume. Carry out the second decoction according to the decocting method in step S3 for 20 minutes; filter to obtain the second decocted medicinal juice; S6: Combine the two decocted medicinal juices in one container and stir evenly to make the concentration of the medicinal juice consistent; S7: Slowly concentrate the combined medicinal juice over a low heat until the water content reaches 50%, cool it to room temperature, sterilize it, and then package it according to the filling requirements to obtain the traditional Chinese medicine aqueous solution.

[0025] Example 2: Prepare a traditional Chinese medicine aqueous solution that is beneficial for healing skin defects according to the following steps S1: Accurately weigh Flos Lonicerae, Herba Taraxaci, Herba Violae, Radix et Rhizoma Rhei, Rhizoma Curcumae, Rhizoma Sparganii, Olibanum, Myrrha, Radix Sanguisorbae, and Radix Astragali, check their appearance and odor to ensure no deterioration or insect damage; the weight parts of each traditional Chinese medicine component are as follows: 15 parts of Flos Lonicerae, 15 parts of Herba Taraxaci, 15 parts of Herba Violae, 10 parts of Radix et Rhizoma Rhei, 10 parts of Rhizoma Curcumae, 10 parts of Rhizoma Sparganii, 10 parts of Olibanum, 10 parts of Myrrha, 10 parts of Radix Sanguisorbae, and 10 parts of Radix Astragali; S2: Put the weighed medicinal materials into a casserole or ceramic container, add clear water at a mass ratio of the traditional Chinese medicine composition to water of 1:5, gently stir to completely immerse the medicinal materials, and soak for 45 minutes; S3: After soaking, first quickly bring the water to a boil over high heat, and then change to low heat to keep it boiling gently and continue decocting for 35 minutes; during the decocting process, stir appropriately to prevent the medicinal materials from sticking to the pot; S4: After decocting, filter the medicinal soup into a clean container to obtain the first decocted medicinal juice, and leave the medicinal residues in the original container; S5: Add clear water to the medicinal residues in S4, where the clear water is half of the first added water volume, and perform the second decocting according to the decocting method in step S3 for 25 minutes; filter to obtain the second decocted medicinal juice; S6: Combine the two decocted medicinal juices in one container, stir evenly to make the concentration of the medicinal juice consistent; S7: Slowly concentrate the combined medicinal juice over a low heat until the water content reaches 50%, cool it to room temperature, sterilize it, and then package it according to the filling requirements to obtain the traditional Chinese medicine aqueous solution.

[0026] Example 3: Prepare a traditional Chinese medicine aqueous solution that is beneficial for healing skin defects according to the following steps S1: Accurately weigh Flos Lonicerae, Herba Taraxaci, Herba Violae, Radix et Rhizoma Rhei, Rhizoma Curcumae, Rhizoma Sparganii, Olibanum, Myrrha, Radix Sanguisorbae, and Radix Astragali, check their appearance and odor to ensure no deterioration or insect damage; the weight parts of each traditional Chinese medicine component are as follows: 18 parts of Flos Lonicerae, 18 parts of Herba Taraxaci, 18 parts of Herba Violae, 12 parts of Radix et Rhizoma Rhei, 12 parts of Rhizoma Curcumae, 12 parts of Rhizoma Sparganii, 12 parts of Olibanum, 12 parts of Myrrha, 12 parts of Radix Sanguisorbae, and 12 parts of Radix Astragali; S2: Put the weighed medicinal materials into a casserole or ceramic container, add clear water at a mass ratio of the traditional Chinese medicine composition to water of 1:6, gently stir to completely immerse the medicinal materials, and soak for 60 minutes; S3: After soaking, first quickly bring the water to a boil over high heat, and then change to low heat to keep it boiling gently and continue decocting for 40 minutes; during the decocting process, stir appropriately to prevent the medicinal materials from sticking to the pot; S4: After the decocting is completed, filter the medicinal broth into a clean container to obtain the first decoction juice, and leave the medicinal residues in the original container. S5: Add clear water to the medicinal residues in S4, where the amount of clear water is half of the amount of water added for the first time, and perform the second decoction according to the decocting method in step S3 for 30 minutes; filter to obtain the second decoction juice. S6: Combine the medicinal juices obtained from the two decoctions in one container and stir evenly to make the concentration of the medicinal juice consistent. S7: Slowly concentrate the combined medicinal juice over a low heat until the water content is 50%, cool it to room temperature, sterilize it, and then package it according to the dispensing requirements to obtain the traditional Chinese medicine aqueous solution.

[0027] The cases of treating with the traditional Chinese medicine aqueous solution of the present invention are as follows: Mr. Wang, 67 years old. He had been lying in bed for a long time after the operation. Due to maintaining the same posture for a long time, severe pressure sores appeared on the lower limb skin. After the family members found out, they immediately contacted our place for treatment. After examination, large areas of skin damage, local tissue necrosis, and purulent secretions were found on the patient's lower limb skin. It was diagnosed as severe pressure sores, and the wound area was about 8×10 cm. The aqueous solution prepared in Example 1 was used for treatment at our place. Before using the drug, first clean the wound surface with normal saline to remove necrotic tissue and secretions, and then dip a sterile cotton ball in an appropriate amount of the traditional Chinese medicine aqueous solution of Example 1 and evenly apply it on the wound surface to keep the wound surface moist. At the initial stage of treatment, there was more exudate on the wound surface, but as the treatment continued, the exudate gradually decreased, the necrotic tissue gradually fell off, and new granulation tissue began to grow. During the treatment process, the patient's pain gradually decreased, and there was no obvious aggravation of infection on the wound surface. After 6 weeks of treatment, the lower limb wound of the patient completely healed, the skin returned to normal, no obvious scar was formed, the patient could move normally, and there was no discomfort complaint. After 3 months of follow-up, there was no recurrence sign on the skin at the wound area of the patient, the patient's life returned to normal, and there were no other complications caused by this pressure sore.

[0028] Mr. Li, 35 years old. He suffered a fibular fracture and skin damage due to a car accident. His family members immediately sent him to our hospital for treatment. After examination, the skin damage at the fibular part of the patient was severe, the local tissue was swollen, and there was bleeding. It was diagnosed as open fracture with soft tissue injury. The aqueous solution prepared in Example 2 was used for treatment at our place. After 6 weeks of treatment, the wound surface of the patient completely healed, the skin returned to normal, no obvious scar was formed, the patient could move normally, and there was no discomfort complaint. After 3 months of follow-up, there was no recurrence sign on the skin at the wound area of the patient, and the patient's life returned to normal.

[0029] Mr. Sun, 53 years old. When cooking at home by himself, he accidentally knocked over hot oil, resulting in his lower extremities being splashed by the hot oil. After the injury, the pain was obvious. His family members immediately sent him to our hospital for treatment. After examination, multiple areas of redness and swelling appeared on the skin of the patient's lower extremities, and blisters and breakages occurred on some of the epidermis. He was diagnosed with superficial second-degree burns, and the burn area was about 12%. Since the patient had a relatively large burn area, the aqueous solution prepared in Example 3 was used for treatment at our place. In the initial stage of treatment, there was a small amount of exudation on the wound surface, but as the treatment continued, the exudation gradually decreased, and the wound surface began to scab. During the treatment process, the patient's pain gradually decreased, and there were no obvious signs of infection on the wound surface. The standard of complete recovery was achieved in the fifth week.

[0030] Mr. Li, 72 years old, had repeated ulcers on the inner side of the left lower leg for 5 years due to long-term varicose veins of the lower extremities. Recently, the wound surface expanded to 6×8 cm, with yellow necrotic tissue attached to the base, accompanied by severe pain, pigmentation of the surrounding skin, and turbid and foul-smelling local exudate. Pseudomonas aeruginosa was detected in the culture of the wound surface secretion. He was diagnosed with chronic venous ulcer complicated with bacterial infection. In the treatment, debridement was first performed to remove the necrotic tissue, and then the aqueous solution prepared in Example 2 was applied externally every day, supplemented with compression bandaging with elastic bandages. After 1 week of treatment, the exudation significantly decreased and the foul smell disappeared; after 3 weeks, the ulcer area shrank to 3×4 cm, and the granulation tissue was fresh; after 6 weeks, the wound surface completely healed, and there was no recurrence during the 3-month follow-up.

[0031] Mr. Liu, 28 years old, did not deal with the wound in time after being bitten by a stray dog on the left forearm. Three days later, the wound showed severe swelling and pain accompanied by yellow pus exudation. When he came to the hospital, the skin around the wound was purple-red, felt hot to the touch, and a 3×4 cm necrotic area formed in the center, accompanied by regional lymph node enlargement. A mixed infection of Pasteurella multocida and Streptococcus pyogenes was detected in the culture of the wound surface secretion. He was diagnosed with grade III dog bite accompanied by progressive cellulitis. After thorough debridement, the aqueous solution prepared in Example 2 was used externally every day. The pain significantly decreased after 2 days of treatment, the swelling area shrank by 50% after 4 days, and the necrotic tissue completely fell off after 1 week. Complete healing was achieved after 2 weeks of treatment, and the scar width was only 1.2 mm. During the 3-month follow-up, there were no recurrence signs on the skin of the patient's wound surface, and the patient's life returned to normal. For the sake of simplicity, the participants in the experiment were grouped and counted as follows: 107 patients aged 5 - 72 years. According to the wound surface type and severity, they were divided into burn and scald categories: 4 cases of first-degree burns; 12 cases of superficial second-degree burns; 18 cases of deep second-degree burns; chronic wound categories: 22 cases of stage III pressure ulcers; 15 cases of diabetic foot ulcers; infectious wound surfaces: 26 cases of postoperative incision infections; 10 cases of traumatic infections.

[0032] Treatment method: 1. After debridement, the traditional Chinese medicine aqueous solution prepared in Example 1 was applied externally to chronic wound surfaces, the traditional Chinese medicine aqueous solution prepared in Example 2 was applied externally to infectious wound surfaces, and the traditional Chinese medicine aqueous solution prepared in Example 3 was applied externally to burn and scald categories; 2. The dressing change frequency was adjusted according to the wound surface type (twice a day for burn and scald, once a day for chronic wound surfaces and infectious wound surfaces).

[0033] The recovery of patients was statistically analyzed, and the following data were obtained: Control group (conventional treatment with silver sulfadiazine): 98 age-matched patients with the same disease distribution as the experimental group.

[0034] Treatment method: 1. Apply 1% silver sulfadiazine cream (National Medicine Approval No. H20057720) after debridement; 2. The dressing change frequency is the same as that of the experimental group.

[0035] The recovery of patients was statistically analyzed, and the following data were obtained: The statistical results are shown in the following table: .

Claims

1. A traditional Chinese medicine aqueous solution beneficial to healing for treating skin defects, characterized in that, The Chinese medicinal components in the Chinese medicinal water preparation include the following raw materials by weight: 12-18 parts of honeysuckle, 12-18 parts of dandelions, 12-18 parts of Viola yedoensis, 8-12 parts of rhubarb, 8-12 parts of Curcuma, 8-12 parts of Trigonum, 8-12 parts of frankincense, 8-12 parts of myrrh, 8-12 parts of Sanguisorba officinalis, and 8-12 parts of Astragalus.

2. Preparation method of traditional Chinese medicine aqueous solution beneficial to healing for treating skin defects, characterized in that, The following steps are involved: S1: Accurately weigh honeysuckle, dandelion, plantain, rhubarb, zedoary, trifoliate green, frankincense, myrrh, sanguisorba officinalis, and astragalus, and check their appearance and smell to ensure that they are not deteriorated or infested by insects; S2: Put the weighed medicinal materials into a casserole or ceramic container, add clean water at a mass ratio of the Chinese medicine composition raw materials to water of 1:4-6, gently stir to fully immerse the medicinal materials, and soak for 30-60 minutes; S3: After soaking, first use high heat to quickly boil the water, then use low heat to keep it at a slight boil and continue to boil for 30-40 minutes; during the boiling process, stir it from time to time to prevent the herbs from sticking to the pot; S4: After the decoction is completed, the medicinal soup is filtered into a clean container to obtain the first decoction, and the medicinal residue is left in the original container; S5: adding clean water to the residue in S4, wherein the clean water is half the amount of water added in the first step, and performing a second decoction according to the decoction method in step S3 for 20-30 minutes; Filter to obtain the second decoction; S6: combining the decoctions obtained from the two decoctions into one container, and stirring evenly to make the concentration of the decoction uniform; S7: Place the combined medicinal juice on a low fire to slowly concentrate it to a water content of 50%, cool it to room temperature, sterilize it, and package it according to the packaging requirements to obtain a Chinese medicine aqueous solution.

3. Preparation method of traditional Chinese medicine aqueous solution beneficial to healing for treating skin defects, characterized in that, The Chinese medicinal liquid is packaged into an external spray.

4. Use of a traditional Chinese medicine aqueous solution beneficial to healing for treating skin defects, characterized in that, The Chinese medicinal liquid is suitable for skin defects caused by bedsores, traffic accident injuries, burns, and varicose vein ulcers of the great saphenous vein.

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