Quantitative evaluation system for sub-health of depression patient based on acupoint resistance characteristics

Abstract

The invention relates to the technical field of personal health risk assessment, and provides a depression patient sub-health quantitative assessment system based on acupoint resistance characteristics, which comprises a high-temperature region acquisition module, a local hardening influence coefficient acquisition module, a sensitization and weakening coefficient acquisition module and an adjustment parameter acquisition module, and is characterized in that a high-temperature region of a depression patient body is determined; according to the difference between the tissue hardness characteristic of each acupoint and the tissue hardness characteristic of the acupoint in the non-high-temperature area, obtaining the local hardening influence coefficient of each acupoint, obtaining the electrical impedance change condition of each acupoint before and after stimulation, and obtaining the sensitization weakening coefficient of each acupoint in combination with the residual error of the corresponding fitting electrical impedance and the overall change degree of the electrical impedance; according to the high-temperature characteristics, the local hardening influence coefficient and the sensitization weakening coefficient of each acupuncture point, the electrical impedance adjustment parameter of each acupuncture point is obtained, the electrical impedance adjustment is realized, the accuracy of the electrical impedance detection result is improved, and the accuracy of the sub-health quantitative evaluation result of the depression patient is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of personal health risk assessment, and in particular to a quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics. Background Art

[0002] For patients with depression, in addition to focusing on their mental symptoms, understanding their physical sub-health status is also crucial. This helps comprehensively assess their health and develop more effective treatment and rehabilitation plans. Existing sub-health assessment methods often rely on subjective questionnaires or single physiological indicator tests, lacking objectivity and comprehensiveness. When the human body is in a sub-healthy or diseased state, organ dysfunction occurs, and the electrical resistance of corresponding meridian acupoints changes. Therefore, by analyzing the electrical resistance characteristics of meridian acupoints, it is possible to assess the sub-health status of depressed patients.

[0003] However, when analyzing the resistance characteristics of meridian acupoints, the electrical impedance of the collected acupoints is easily affected by many factors. This is mainly because the psychological health of depressed patients affects their living habits, eating habits, work and rest, etc., resulting in physical symptoms, which in turn leads to changes in the skin environment, stratum corneum, etc., affecting the adhesion of the resistance patch. In addition, the physical symptoms of depression are often related to systemic low-grade inflammation, which causes changes in body temperature, further affecting the electrical impedance test results, resulting in certain differences between the electrical impedance test results and the actual physical condition of the depressed patients, affecting the accuracy of the electrical impedance test results, and thus affecting the accuracy of the quantitative assessment results of sub-health in depressed patients. Summary of the Invention

[0004] In order to solve the technical problem of low accuracy of electrical impedance detection results for patients with depression, the present invention aims to provide a quantitative assessment system for sub-health of patients with depression based on acupoint resistance characteristics. The technical solution adopted is as follows:

[0005] The present invention provides a quantitative assessment system for sub-health status of depressed patients based on acupoint resistance characteristics, comprising:

[0006] A high temperature region acquisition module is used to determine the high temperature region of the body of the depressed patient; the high temperature region is obtained by the high temperature characteristics of each acupoint, and the high temperature characteristics are obtained by the temperature of each acupoint;

[0007] a local induration influence coefficient acquisition module, configured to obtain the local induration influence coefficient of each acupoint based on the difference between the tissue hardness characteristics of each acupoint and the tissue hardness characteristics of the acupoints in other areas outside the high temperature area;

[0008] The sensitization and weakening coefficient acquisition module is used to obtain the electrical impedance change sequence before and after acupoint stimulation of each acupoint, and obtain the sensitization and weakening coefficient of each acupoint based on the residual fluctuation of the corresponding fitting line and the overall change degree of the electrical impedance;

[0009] The adjustment parameter acquisition module is used to obtain the electrical impedance adjustment parameters of each acupoint according to the high temperature characteristics, local nodule influence coefficient and sensitization weakening coefficient of each acupoint.

[0010] In an exemplary embodiment, the process of obtaining the local hardening influence coefficient includes:

[0011] Obtaining an average value of tissue hardness characteristics of all acupuncture points in areas other than the high temperature area;

[0012] The difference between the tissue hardness characteristic of the target acupoint and the average value of the tissue hardness characteristic is obtained to obtain the local induration influence coefficient of the target acupoint; the target acupoint is any acupoint.

[0013] In an exemplary embodiment, the process of obtaining the overall change degree of the electrical impedance includes:

[0014] Acquiring an overall electrical impedance change sequence, wherein the overall electrical impedance change sequence is obtained by splicing the electrical impedance change sequence before acupoint stimulation and the electrical impedance change sequence after acupoint stimulation;

[0015] A fitting straight line of the overall electrical impedance change sequence is obtained, where the overall electrical impedance change degree is the absolute value of the slope of the fitting straight line.

[0016] In an exemplary embodiment, the process of obtaining the sensitization weakening coefficient includes:

[0017] Obtaining a first residual sequence and a second residual sequence; the first residual sequence is a residual sequence of an electrical impedance change sequence of a target acupoint before acupoint stimulation and a fitted straight line, and the second residual sequence is a residual sequence of an electrical impedance change sequence of a target acupoint after acupoint stimulation and a fitted straight line, wherein the target acupoint is any acupoint;

[0018] Obtaining a variance difference between the second residual sequence and the first residual sequence;

[0019] The sensitization weakening coefficient of the target acupuncture point is obtained according to the overall change degree of the electrical impedance of the target acupuncture point and the variance difference.

[0020] In an exemplary embodiment, obtaining the sensitization coefficient of the target acupoint according to the overall change degree of the electrical impedance of the target acupoint and the variance difference includes:

[0021] The product of the overall change degree of the electrical impedance and the variance difference is calculated, and negative correlation normalization is performed to obtain the sensitization weakening coefficient.

[0022] In an exemplary embodiment, the electrical impedance adjustment parameter of the target acupuncture point includes an intermediate adjustment parameter and a final adjustment parameter of the target acupuncture point; the target acupuncture point is any acupuncture point;

[0023] The intermediate adjustment parameter of the target acupoint is equal to the sum of the value 1 and the high temperature coefficient of the target acupoint; wherein, if the target acupoint is in the high temperature area, the high temperature coefficient of the target acupoint is the average value of the high temperature characteristics of each acupoint in the high temperature area; if the target acupoint is not in the high temperature area, the high temperature coefficient of the target acupoint is 0;

[0024] The final adjustment parameter of the target acupoint is equal to the product of the local induration influence coefficient of the target acupoint and the sensitization increase coefficient of the target acupoint, and the sensitization increase coefficient of the target acupoint is equal to the sum of the value 1 and the sensitization weakening coefficient of the target acupoint.

[0025] In an exemplary embodiment, the sub-health quantitative assessment system for depression patients based on acupoint resistance characteristics further includes an electrical impedance adjustment module, which is configured to perform the following adjustment process:

[0026] c′ j,b =c j,b *ω j,1 ;

[0027]

[0028] Among them, c j,b is the initial electrical impedance of the jth acupoint at the bth moment, v j,1 is the intermediate adjustment parameter of the jth acupoint, c′ j,b is the intermediate electrical impedance of the jth acupoint at the bth moment, is the average value of the intermediate electrical impedance of the jth acupoint at all times, is the average value of the initial electrical impedance of the jth acupoint at all times, ω j,2 is the final adjustment parameter of the jth acupoint, c″ j,b is the final electrical impedance of the jth acupoint at the bth moment.

[0029] In an exemplary embodiment, the process of acquiring the high temperature characteristics includes:

[0030] Obtaining a first difference of a target acupuncture point, where the first difference is a difference between a temperature of the target acupuncture point and a preset priori temperature of the target acupuncture point; the target acupuncture point is any acupuncture point;

[0031] Obtaining a second difference of the target acupuncture point, where the second difference is a difference between the temperature of the target acupuncture point and an average temperature of all acupuncture points;

[0032] The first difference and the second difference are integrated to obtain the high temperature characteristic of the target acupuncture point.

[0033] In an exemplary embodiment, the process of obtaining the high temperature region includes:

[0034] The high temperature characteristics of each acupoint are compared with a preset high temperature characteristic threshold, and the area formed by adjacent acupoints in the acupoints corresponding to the high temperature characteristics greater than the preset high temperature characteristic threshold is regarded as a high temperature area.

[0035] In an exemplary embodiment, the tissue hardness characteristic is a Young's modulus value.

[0036] The present invention has the following beneficial effects: since the body temperature of a depressed patient will affect the electrical impedance of each acupuncture point, the high temperature area of the depressed patient's body is first obtained based on the temperature of each acupuncture point. Since the high temperature area is often accompanied by local inflammation, and local inflammation can cause the tissue hardness of the acupuncture point to change, the local induration influence coefficient of each acupuncture point is obtained according to the tissue hardness characteristics of each acupuncture point. Before and after the acupuncture point stimulation of a depressed patient, normal people and depressed patients will have different reactions to the stimulation, and the sensitization weakening coefficient of each acupuncture point is obtained according to the change of the electrical impedance before and after the acupuncture point stimulation. The high temperature characteristics, local induration influence coefficient and sensitization weakening coefficient of each acupuncture point jointly determine the electrical impedance adjustment amplitude of the acupuncture point, and the electrical impedance adjustment parameters of each acupuncture point are obtained according to the high temperature characteristics, local induration influence coefficient and sensitization weakening coefficient of each acupuncture point. When the electrical impedance of each acupuncture point is adjusted according to the electrical impedance adjustment parameters of each acupuncture point, the adjusted electrical impedance matches the actual physical condition of the depressed patient, thereby improving the accuracy of the electrical impedance detection results, thereby improving the accuracy of the quantitative assessment results of sub-health of depressed patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] Figure 1 This is a schematic structural diagram of a system for quantitatively assessing sub-health of depressed patients based on acupoint resistance characteristics, provided by one embodiment of the present invention;

[0038] Figure 2 This is a flowchart of the steps corresponding to various modules of a system for quantitatively evaluating sub-health of depressed patients based on acupoint resistance characteristics, provided by one embodiment of the present invention;

[0039] Figure 3 is a flow chart for obtaining high temperature characteristics provided by one embodiment of the present invention;

[0040] Figure 4 This is a flow chart for obtaining a local induration influence coefficient provided by one embodiment of the present invention;

[0041] Figure 5 This is a flow chart for obtaining the overall change degree of electrical impedance provided by one embodiment of the present invention;

[0042] Figure 6 This is a flow chart for obtaining a sensitization weakening coefficient provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0043] To further illustrate the technical means and effects employed by the present invention to achieve its intended objectives, the following detailed description of the specific embodiments, structures, features, and effects of the present invention is provided in conjunction with the accompanying drawings and preferred embodiments. In the following description, references to "one embodiment" or "another embodiment" do not necessarily refer to the same embodiment. Furthermore, specific features, structures, or characteristics of one or more embodiments may be combined in any suitable manner.

[0044] Unless otherwise defined, all technical and scientific terms used herein have the same meanings as commonly understood by those skilled in the art to which this invention pertains. The data and information collected in this application were obtained with full consent and authorization.

[0045] When the human body is in a pathological state, the activity of acupoints, which are reaction points on the body surface, increases significantly, which can be clearly observed from physical signs. For example, acupoints may experience obvious pain when pressed, patients may report abnormal heat in the acupoint area, or the acupoints may undergo visible changes in appearance, such as swelling or color change. These physical signs provide important diagnostic clues for TCM acupuncture and moxibustion. These acupoints are also called sensitized acupoints. Sensitized acupoints, also known as reaction points or pathological reaction points, refer to specific acupoints that show abnormal sensitivity (such as tenderness, nodules, temperature changes, etc.) when the human body is ill. These acupoints are closely related to the disease state.

[0046] However, due to differences in the onset time and physical signs of depression among different patients, sensitized acupoints may shift or disappear as the condition progresses or resolves (e.g., tenderness at the Weizhong acupoint in the early stages of acute low back pain shifts to the Shenshu acupoint in later stages). This leads to individualized differences in the electrical impedance of sensitized acupoints. Furthermore, because depression often presents with physical symptoms, which particularly affect the surface of the skin, the electrical impedance of acupoints measured using resistance sheets can vary. Sensitized acupoints vary from person to person, and their location and intensity of response vary from person to person, requiring a comprehensive diagnosis.

[0047] Depressed patients usually have the following conditions: Hypothalamic dysfunction: Abnormalities in the HPA axis (hypothalamic-pituitary-adrenal axis) in depressed patients may interfere with the body temperature regulation center, leading to body temperature fluctuations, such as long-term low fever or subjective chills / fever; decreased basal metabolic rate: The reduced physical activity and energy metabolism associated with depression may lead to a slight drop in basal body temperature; autonomic nervous system disorders: Abnormalities in the sympathetic nerves may trigger vasoconstriction (cold hands and feet) or hot flashes and sweating, affecting the perceived temperature.

[0048] Therefore, the present invention analyzes the electrical impedance and body surface information of different acupoints of depressed patients, adjusts and corrects the electrical impedance measured at different acupoints, and thus eliminates the problem of electrical impedance differences caused by physical symptoms of depressed patients.

[0049] This embodiment provides a quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics. The application scenario is as follows: during the test process, more or less depressed patients will have certain mood swings, and when performing acupoint impedance testing, emotions will be induced, causing the skin of depressed patients to become moist, thereby reducing the impedance of each acupoint. However, for anxious and depressed people, due to their long-term exposure to negative and anxious emotions, their skin will become moist for a long time, causing the impedance to remain at a low level for a long time. In addition, depression is often accompanied by nutritional intake and endocrine problems, resulting in poor nutritional intake in depressed patients. The combined reasons cause the thinning of the skin stratum corneum and the fragility of the skin barrier, which in turn reduces the impedance. In addition, when performing emotion-induced impedance testing, anxious and depressed people, due to their long-term exposure to negative emotions, often react to external stimuli in an extreme or unresponsive manner.

[0050] At the same time, under disease conditions, the physiological state of acupoints changes. The release and accumulation of inflammatory mediators around the lesions, such as interleukins and tumor necrosis factors, not only directly participate in the inflammatory response, causing the temperature of the acupoints to rise, but also regulate the sensitivity of nerve fibers, enhance pain transmission, and induce edema of the tissues around the acupoints. At the same time, the sensitivity of nerve endings increases under pathological conditions, and the nerve endings' ability to recognize external stimuli is enhanced, and the transmission efficiency is improved, thereby amplifying the intensity of the acupoints' response to stimuli. When edema of the surrounding tissues is induced, subcutaneous nodules, cords, or muscle tension can be felt at the acupoints, causing local induration / cords at the acupoints. Local induration / cords refer to subcutaneous nodules, cords, or muscle tension that can be felt at the acupoints, which can be detected by ultrasound elastography.

[0051] This embodiment provides a quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics. Figure 1As shown, it includes: a high temperature area acquisition module, a local induration influence coefficient acquisition module, a sensitization weakening coefficient acquisition module and an adjustment parameter acquisition module. Each module can be a software module, which is essentially a corresponding method step; it can also be a hardware module, and the executed method steps are configured in the hardware module so that the hardware module realizes the corresponding function. Accordingly, the sub-health quantitative assessment system for depressed patients based on acupoint resistance characteristics can be a software system, configured in relevant processors, computer hosts, and related medical platforms; it can also be a hardware system, such as a server, computer host, etc. This embodiment does not limit the specific configuration of each module and the sub-health quantitative assessment system for depressed patients based on acupoint resistance characteristics.

[0052] like Figure 2 As shown, the method steps corresponding to each module are as follows:

[0053] A high temperature region acquisition module is used to determine the high temperature region of the body of a depressed patient; the high temperature region is obtained by the high temperature characteristics of each acupoint, and the high temperature characteristics are obtained by the temperature of each acupoint;

[0054] A local induration influence coefficient acquisition module is used to obtain the local induration influence coefficient of each acupoint based on the difference between the tissue hardness characteristics of each acupoint and the tissue hardness characteristics of acupoints in other areas outside the high temperature area;

[0055] The sensitization and weakening coefficient acquisition module is used to obtain the electrical impedance change sequence before and after acupoint stimulation of each acupoint, and obtain the sensitization and weakening coefficient of each acupoint based on the residual fluctuation of the corresponding fitting line and the overall change degree of the electrical impedance;

[0056] The adjustment parameter acquisition module is used to obtain the electrical impedance adjustment parameters of each acupoint according to the high temperature characteristics, local nodule influence coefficient and sensitization weakening coefficient of each acupoint.

[0057] The specific implementation process of each module is described below in conjunction with the accompanying drawings.

[0058] To identify high-temperature areas on a depressed patient's body, the high-temperature region acquisition module needs to obtain the temperature of each acupuncture point on the patient's body. In one exemplary embodiment, thermal infrared sensors are placed at each acupuncture point to obtain the temperature of each acupuncture point on the patient's body. An increase in acupuncture point temperature indicates heat sensitivity, while a decrease in temperature indicates cold sensitivity.

[0059] When the electrical impedance of each acupoint is subsequently collected, a certain amount of emotion induction will be added thereto, for example, acupuncture needles are used to prick each acupoint of the patient, thereby measuring the patient's emotional fluctuations. Then, in an exemplary embodiment, an emotion induction time period is set, and the data obtained in this embodiment is the data information within the emotion induction time period. More preferably, the emotion induction moment of each acupoint (i.e., the acupoint stimulation moment) is the middle moment of the emotion induction time period, so that the emotion induction time period is divided into two sections, the first section is the time period before the acupoint stimulation, and the second section is the time period after the acupoint stimulation.

[0060] In order to ensure the reliability of the temperature during data processing, the temperature of each acupoint collected in this embodiment is the temperature at the end moment of the emotion induction time period.

[0061] Depression often leads to neurotransmitter imbalances. For example, substance P can trigger local inflammation in patients with depression, leading to systemic low-grade inflammation. Because meridians and acupoints connect to internal and physiological systems via nerve endings, when neurotransmitters trigger inflammation in the body, inflammatory mediators are released and accumulate around the lesion. These mediators, such as interleukins and tumor necrosis factor, not only directly participate in the inflammatory response but also modulate nerve fiber sensitivity, enhance pain transmission, and induce edema in surrounding tissues. Furthermore, under pathological conditions, nerve endings become more sensitive, their ability to recognize external stimuli increases, and transmission efficiency improves, thereby amplifying the intensity of acupoint responses to stimulation. Furthermore, when inflammation occurs in the human body, the body initiates the inflammatory process, releasing inflammatory mediators such as prostaglandins and interleukins. These mediators cause vasodilation, increase local blood flow and heat generation, and result in localized hyperthermia. Higher skin surface temperatures reduce the skin's electrical impedance, which in turn reduces the electrical impedance of acupoints located in these areas. Therefore, the temperature of each acupoint is first determined to identify these areas of high temperature.

[0062] First, the high temperature characteristics of each acupoint are obtained based on the temperature of each acupoint. The high temperature characteristics are the high temperature performance of the acupoint, which characterizes the high temperature situation of the acupoint temperature. The higher the temperature of the acupoint is compared with the temperature of other acupoints, the more obvious the high temperature characteristics of the acupoint are. In an exemplary embodiment, Figure 3 As shown, a specific process of obtaining high temperature characteristics is given as follows:

[0063] Step 1-1: Obtain a first difference of a target acupuncture point, where the first difference is a difference between a temperature of the target acupuncture point and a preset priori temperature of the target acupuncture point.

[0064] It should be understood that each acupoint has a preset temperature, which is set to the temperature of the acupoint in a normal person under normal conditions. It should be understood that the preset prior temperatures of various acupoints may be the same or different, depending on the actual conditions of the acupoint. Therefore, the greater the difference between the acupoint temperature (i.e., the actual temperature collected) and its preset prior temperature, the more pronounced the high temperature characteristic of the acupoint.

[0065] For ease of explanation, the target acupoint is set to any acupoint. The temperature of the target acupoint is calculated by subtracting the preset prior temperature of the target acupoint, and the difference obtained is used as the first difference of the target acupoint. It should be understood that the first difference may be positive or negative. When it is a positive value, it means that the temperature of the target acupoint is greater than the preset prior temperature of the target acupoint, and it has a certain high temperature characteristic. The larger the positive value, the more obvious the high temperature characteristic of the target acupoint.

[0066] Step 1-2: Obtain a second difference of the target acupoint, where the second difference is the difference between the temperature of the target acupoint and the average temperature of all acupoints.

[0067] The average temperature of all acupoints is obtained. The average temperature of all acupoints represents the overall body temperature of the depressed patient. The temperature of the target acupoint is calculated by subtracting the average temperature of all acupoints, and the difference obtained is used as the second difference of the target acupoint. It should be understood that the second difference may be positive or negative. When it is a positive value, it indicates that the temperature of the target acupoint is greater than the average temperature of all acupoints, indicating that it has a certain high temperature characteristic. The larger the positive value, the more obvious the high temperature characteristic of the target acupoint.

[0068] Step 1-3: Fusion the first difference and the second difference to obtain the high temperature characteristics of the target acupuncture point.

[0069] The first difference and the second difference of the target acupuncture point are fused. In an exemplary embodiment, a fusion method is given as follows: the sum of the first difference and the second difference is calculated, the sum is defined as the difference sum, and the difference sum is normalized, and the result obtained is the high temperature feature of the target acupuncture point.

[0070] In an exemplary embodiment, the normalization method is as follows: obtaining the maximum and minimum values of the difference sum values of all acupoints, and then normalizing the difference sum value of the target acupoint using the maximum and minimum normalization method to obtain the high temperature signature of the target acupoint. Furthermore, the high temperature signature of each acupoint is obtained.

[0071] Since the higher the temperature of an acupoint is, the more obvious its high temperature characteristic is, then, as another implementation method, the temperature of each acupoint can be directly normalized, and the obtained result can be used as the high temperature characteristic of each acupoint.

[0072] Then, based on the high temperature characteristics of each acupuncture point, the high temperature area of the body is obtained. Since the more obvious the high temperature characteristics, that is, the larger the high temperature characteristic value, the more the location of the acupuncture point belongs to the high temperature area, then a high temperature characteristic threshold is preset. This preset high temperature characteristic threshold is used to compare with the high temperature characteristics of each acupuncture point to determine whether the high temperature characteristics of each acupuncture point are high, thereby screening for high high temperature characteristics. It should be understood that the numerical range of the preset high temperature characteristic threshold is 0-1. Under the premise of meeting the above-mentioned judgment requirements, the specific numerical value of the preset high temperature characteristic threshold is flexibly set by the implementer. In this embodiment, the preset high temperature characteristic threshold is set to 0.7.

[0073] The high temperature characteristics of each acupoint are compared with a preset high temperature characteristic threshold, and the acupoint corresponding to the high temperature characteristic greater than the preset high temperature characteristic threshold is obtained and defined as a high temperature acupoint. Adjacent high temperature acupoints are merged to form a region as a high temperature region, thereby obtaining at least one high temperature region. It should be understood that for isolated high temperature acupoints, that is, there are no adjacent high temperature acupoints, this may be due to interference from the external environment. In this case, the isolated high temperature acupoint is determined as a non-high temperature acupoint and not as a separate high temperature region.

[0074] The local induration influence coefficient acquisition module first needs to obtain the tissue hardness characteristics of each acupoint. In one exemplary embodiment, the tissue hardness characteristics are Young's modulus values. Furthermore, the tissue hardness characteristics of each acupoint are collected at the end of the emotion-induced time period. That is, the tissue hardness characteristics of each acupoint are the tissue hardness characteristics of each acupoint at the end of the emotion-induced time period.

[0075] Shear wave elastography is used to obtain the Young's modulus value of each acupoint. Specifically, an ultrasound probe is applied to each acupoint and emits a focused acoustic radiation force pulse. The acoustic pressure component forms multiple focal points at different depths in the tissue, generating lateral displacement and exciting shear waves. The ultrasound probe then emits high-frequency ultrasonic pulses and receives echo signals reflected by the tissue, capturing the dynamic displacement of the tissue caused by the shear waves. The propagation time difference of the shear wave at different locations is tracked, and its propagation velocity is calculated. The shear modulus is then used to obtain the Young's modulus value. A larger Young's modulus indicates greater tissue hardness at the acupoint. Furthermore, acupoint sensitization is often accompanied by an increase in local tissue hardness (such as fascial adhesions or inflammatory reactions). Shear wave elastography can dynamically monitor changes in acupoint elasticity before and after acupuncture.

[0076] Based on the above logic, when the temperature of a depressed patient's acupoint increases, its electrical impedance will decrease. Therefore, the electrical impedance of the acupoint can be amplified by the high temperature area where the acupoint is located. However, at the same time, high temperature areas are often accompanied by local inflammation, which means that these acupoints will become sensitized acupoints. Sensitized acupoints can better reflect the patient's sub-health condition. On the other hand, due to individual differences among patients, the manifestation of sensitized acupoints in different diseases is not fixed, so the electrical impedance of sensitized acupoints needs to be corrected.

[0077] Because usually, only some acupoints in different diseases are sensitized acupoints, and sensitized acupoints will increase tissue hardness due to the accumulation of inflammatory factors, that is, the Young's modulus value increases, so the local induration influence coefficient of each acupoint is obtained based on the difference between the tissue hardness characteristics of each acupoint and the tissue hardness characteristics of acupoints in other areas outside the high temperature area. In an exemplary embodiment, Figure 4 As shown, a specific process for obtaining the local hardening influence coefficient is given as follows:

[0078] Step 2-1: Obtain the average value of the tissue hardness characteristics of all acupuncture points in areas other than the high-temperature area.

[0079] The patient's body is divided into two areas based on the high temperature area: one is the high temperature area, and the other is the area other than the high temperature area. The area other than the high temperature area is defined as the non-high temperature area. Both the high temperature area and the non-high temperature area contain multiple acupuncture points.

[0080] The tissue hardness characteristics of each acupoint within the non-high-temperature region were obtained, and then the average tissue hardness characteristics of all acupoints within the non-high-temperature region were calculated to represent the overall tissue hardness characteristics of the non-high-temperature region. The non-high-temperature region represents the area where all acupoints that have not undergone sensitization are located, and the average tissue hardness characteristics of all acupoints represent the average tissue hardness characteristics of the non-sensitized acupoints.

[0081] In addition, the high temperature coefficient of each acupoint is obtained. For a target acupoint, if the target acupoint is located in a high temperature region, the high temperature region in which the target acupoint is located is defined as the target high temperature region. The average value of the high temperature characteristics of each acupoint within the target high temperature region (i.e., the high temperature region in which the target acupoint is located) is calculated as the high temperature coefficient of the target acupoint. In this way, the high temperature coefficients of all acupoints belonging to the same high temperature region are equal. If the target acupoint is not located in the high temperature region, i.e., in a non-high temperature region, the high temperature coefficient of the target acupoint is 0. Thus, the high temperature coefficient of each acupoint is obtained. The average value of the tissue hardness characteristics of all acupoints in the non-high temperature region is the average value of the tissue hardness characteristics of all acupoints with a high temperature coefficient of 0.

[0082] Step 2-2: Obtain the difference between the tissue hardness characteristic of the target acupuncture point and the average value of the tissue hardness characteristic to obtain the local induration influence coefficient of the target acupuncture point.

[0083] Because the more likely an acupoint is a sensitized acupoint, the higher its tissue hardness characteristic is compared to other acupoints. Therefore, the difference between the tissue hardness characteristic of the target acupoint and the average tissue hardness characteristic of the non-high-temperature area is calculated, and the resulting difference is defined as the tissue hardness characteristic difference. This tissue hardness characteristic difference of the target acupoint is then normalized to obtain the local induration influence coefficient of the target acupoint.

[0084] In an exemplary embodiment, the normalization method is as follows: the maximum and minimum values of the tissue hardness characteristic differences of all acupoints are obtained, and then the tissue hardness characteristic differences of the target acupoint are normalized using the maximum-minimum normalization method to obtain the local induration influence coefficient of the target acupoint. Furthermore, the local induration influence coefficient of each acupoint is obtained.

[0085] The larger the difference in tissue hardness characteristics, the higher the tissue hardness characteristics of the target acupoint are compared with the tissue hardness characteristics of other acupoints, and the more likely the target acupoint is to be sensitized.

[0086] The sensitization coefficient acquisition module first needs to acquire the electrical impedance of each acupoint. In one exemplary embodiment, the acupoint impedance acquisition process is as follows: all acupoints are wiped with alcohol pads to reduce interference factors such as sweat, oil, and dandruff. After attaching the flexible electrode sheet, align the inner ring with the acupoint location and apply it to the patient's acupoint. The electrical impedance of each acupoint is measured using an acupoint electrical detector, which works based on the principle that reduced impedance increases conductivity. Furthermore, during the emotion-induced time period, the electrical impedance of each acupoint is collected at each moment according to a preset sampling period. The duration of the emotion-induced time period is set based on actual needs, such as 5 minutes, and the sampling period is set based on actual conditions, such as once every second. Thus, for any acupoint, the electrical impedance is acquired at multiple moments during the emotion-induced time period. During the acquisition process, depressed patients are instructed not to move any part of their body and maintain a normal breathing rate to ensure data accuracy. After the acquisition is completed, the flexible electrode sheet is removed and stored, and the electrode attachment site is wiped with an alcohol pad to prevent adhesive residue.

[0087] When conducting an emotion-induced electrical impedance test, depressed patients, due to long-term troubles caused by negative emotions, often show extreme or no reaction to external stimuli, and the electrical impedance of the sensitized acupoints of depressed patients often shows no fluctuation. Normal people will have certain mood swings more or less during the test. And emotion induction will cause the skin of normal people to be moist, thereby reducing the electrical impedance of each acupoint. However, for anxious and depressed people, due to their long-term influence of negative and anxious emotions, the skin will be moist for a long time, and depression is often accompanied by nutritional intake and endocrine problems, resulting in poor nutritional intake of depressed patients, which leads to a combination of reasons causing the thinning of the skin stratum corneum and the fragility of the skin barrier, thereby causing the electrical impedance to remain at a low state, and not a reduction caused by emotion induction. Therefore, the present invention analyzes whether the patient will show a reduction in the electrical impedance of the sensitized acupoints during the emotion-induced time period. If there is no reduction, it indicates that the patient may have been troubled by negative emotions for a long time, and the reaction to external stimuli is often shown as extreme or no reaction.

[0088] When conducting sub-health assessment of depressed patients based on acupoints, the analysis is conducted through the differences in acupoints with the same name on both sides of the body. Depressed patients are often accompanied by factors such as thinning of the skin stratum corneum, which leads to a weakening of the dynamic response of the electrical impedance of sensitized acupoints and a decrease in electrical impedance caused by high temperature of inflammation, resulting in errors in sub-health assessment. Therefore, it is necessary to analyze the changes in the electrical impedance of each acupoint during the emotion-induced time period to obtain the sensitization weakening coefficient of each acupoint. Specifically: obtain the electrical impedance change sequence before and after acupoint stimulation of each acupoint, and obtain the sensitization weakening coefficient of each acupoint based on the residual fluctuation with the corresponding fitting straight line and the overall change degree of electrical impedance.

[0089] Acupuncture is performed on the target acupoints at the middle of the emotion induction time period to induce the emotion. Then, the electrical impedance of the target acupoints at each moment in the pre-stimulation time period is obtained and arranged in time sequence to obtain a pre-stimulation impedance change sequence. Similarly, the electrical impedance of the target acupoints at each moment in the post-stimulation time period is obtained and arranged in time sequence to obtain a post-stimulation impedance change sequence.

[0090] Obtain the overall change degree of the electrical impedance of the target acupoint during the emotion induction time period. In an exemplary embodiment, Figure 5 As shown, a specific process for obtaining the overall change degree of electrical impedance is given as follows:

[0091] Step 3-1: Obtain the overall electrical impedance change sequence.

[0092] The electrical impedance change sequence before and after acupoint stimulation of the target acupoint is spliced in time sequence to obtain the overall electrical impedance change sequence of the target acupoint.

[0093] Step 3-2: Obtain a fitting straight line of the overall change sequence of the electrical impedance. The overall change degree of the electrical impedance is the absolute value of the slope of the fitting straight line.

[0094] A linear fit is performed on the overall change sequence of the electrical impedance of the target acupoint to obtain a fitted straight line. The absolute value of the slope of the fitted straight line is obtained, and the absolute value of the slope of the fitted straight line is used as the overall change degree of the electrical impedance of the target acupoint. Then, the larger the absolute value of the slope of the fitted straight line, the higher the overall change degree of the electrical impedance. Since the skin of a normal person will be moistened after emotional induction, the electrical impedance of the acupoint will decrease, so the slope of the fitted straight line is a negative value. However, the electrical impedance of the acupoint of a depressed patient does not decrease much, so the slope of the fitted straight line may be a small negative value, 0, or a small positive value.

[0095] After emotional induction, a normal person's skin becomes moist, which reduces the electrical impedance of acupoints. However, due to the long-term negative emotions of depressed patients, their response to external stimuli is not obvious, and the electrical impedance of acupoints does not change significantly. Therefore, the smaller the overall change in electrical impedance, the more chronic the negative emotions are, which leads to a lack of response to external stimuli.

[0096] Then, based on the electrical impedance change sequence before and after acupoint stimulation of the target acupoint, as well as the residual fluctuation of the corresponding fitting straight line and the overall change degree of the electrical impedance of the target acupoint, the sensitization weakening coefficient of the target acupoint is obtained. In an exemplary embodiment, Figure 6 As shown, a specific process of obtaining the sensitization weakening coefficient is given as follows:

[0097] Step 3-3: Obtain a first residual sequence and a second residual sequence.

[0098] Perform linear fitting on the electrical impedance change sequence of the target acupoint before acupoint stimulation to obtain a fitted straight line corresponding to the electrical impedance change sequence before acupoint stimulation, which is defined as the first fitted straight line. Obtain the residual sequence between the electrical impedance change sequence of the target acupoint before acupoint stimulation and the first fitted straight line, which is defined as the first residual sequence. Specifically: calculate the difference between the actual electrical impedance and the fitted electrical impedance at each moment in the electrical impedance change sequence of the target acupoint before acupoint stimulation and the first fitted straight line, and construct the first residual sequence based on the difference at each moment. Among them, the actual electrical impedance is the electrical impedance at each moment in the electrical impedance change sequence before acupoint stimulation, and the fitted electrical impedance is the electrical impedance at each moment on the first fitted straight line.

[0099] Similarly, a straight line fitting is performed on the electrical impedance change sequence of the target acupoint after acupoint stimulation to obtain a fitting straight line corresponding to the electrical impedance change sequence after acupoint stimulation, which is defined as the second fitting straight line. The residual sequence of the electrical impedance change sequence of the target acupoint after acupoint stimulation and the second fitting straight line is obtained, which is defined as the second residual sequence. Specifically: the difference between the actual electrical impedance and the fitted electrical impedance at each moment in the electrical impedance change sequence of the target acupoint after acupoint stimulation and the second fitting straight line is calculated, and the second residual sequence is constructed according to the difference at each moment.

[0100] Step 3-4: Obtain the variance difference between the second residual sequence and the first residual sequence.

[0101] The variance of the first residual sequence is calculated to characterize the residual fluctuation of the first residual sequence; the variance of the second residual sequence is calculated to characterize the residual fluctuation of the second residual sequence.

[0102] The variance of the second residual sequence is calculated by subtracting the variance of the first residual sequence, and the obtained difference is used as the variance difference between the second residual sequence and the first residual sequence.

[0103] After emotional induction, the electrical impedance of acupoints in normal individuals will fluctuate to a certain extent. That is, the variance of the first residual sequence will be smaller than the variance of the second residual sequence, and there will be a certain difference between the two. However, due to the long-term negative emotions that plague depressed patients, their response to external stimuli is not obvious, and the fluctuation of the electrical impedance of the acupoints is not obvious. That is, the variance of the first residual sequence is not much different from the variance of the second residual sequence.

[0104] Then, the smaller the value of the variance difference between the second residual sequence and the first residual sequence, the smaller the fluctuation of the electrical impedance of the target acupoint before and after the emotion induction, which means that the depressed patient is more likely to be troubled by negative emotions for a long time, resulting in a lack of obvious response to external stimuli.

[0105] Step 3-5: According to the overall change degree and variance difference of the electrical impedance of the target acupoint, the sensitization and weakening coefficient of the target acupoint is obtained.

[0106] According to the overall change degree and variance difference of the electrical impedance of the target acupoint, the sensitization and weakening coefficient of the target acupoint is obtained, wherein the sensitization and weakening coefficient is inversely proportional to the overall change degree and variance difference of the electrical impedance.

[0107] In an exemplary embodiment, the product of the overall change degree of the electrical impedance of the target acupoint and the variance difference is calculated and defined as the characteristic product. The characteristic product is then negatively normalized, and the result obtained is the sensitization and weakening coefficient of the target acupoint. The negative correlation normalization method here can be: obtaining the maximum and minimum values of the characteristic products of all acupoints, and then normalizing the characteristic product of the target acupoint using the maximum and minimum normalization method, and finally calculating the difference between the value 1 and the normalized characteristic product of the target acupoint (to achieve negative correlation normalization), and the result obtained is the sensitization and weakening coefficient of the target acupoint.

[0108] Using the above process, the sensitization coefficient of each acupoint is obtained. The sensitization coefficient indicates the degree to which the electrical impedance of an acupoint needs to be adjusted if it is a sensitized acupoint. The larger the sensitization coefficient, the greater the degree to which the electrical impedance of the acupoint needs to be adjusted if it is a sensitized acupoint.

[0109] For the adjustment parameter acquisition module, through the above process, the local induration influence coefficient and sensitization weakening coefficient of each acupoint are obtained, wherein the local induration influence coefficient characterizes the possibility that each acupoint belongs to a sensitized acupoint, and the sensitization weakening coefficient reflects the change in electrical impedance during the emotional excitation process. Then when an acupoint belongs to a sensitized acupoint, it is necessary to increase the information content of its electrical impedance during the emotional excitation process, that is, to increase the fluctuation amplitude of its electrical impedance. At the same time, if there is inflammation in the sensitized acupoint, the increase in temperature will cause the overall electrical impedance of the acupoint to decrease. Therefore, the intermediate adjustment parameter (that is, the overall adjustment parameter) is obtained through the high temperature coefficient of each acupoint, and the final adjustment parameter (that is, the amplitude adjustment coefficient) is obtained through the local induration influence coefficient and sensitization weakening coefficient of the acupoint, thereby constituting the electrical impedance adjustment parameter of each acupoint.

[0110] Taking a target acupoint as an example, the electrical impedance adjustment parameters of the target acupoint include the intermediate adjustment parameters and the final adjustment parameters of the target acupoint. The intermediate adjustment parameters of the target acupoint are equal to the sum of the value 1 and the high temperature coefficient of the target acupoint. The process of obtaining the final adjustment parameters of the target acupoint includes: calculating the sum of the value 1 and the sensitization weakening coefficient of the target acupoint to obtain the sensitization increase coefficient of the target acupoint, and then calculating the product of the local induration influence coefficient of the target acupoint and the sensitization increase coefficient of the target acupoint as the final adjustment parameter of the target acupoint.

[0111] Taking the jth acupoint as an example, the calculation formula is as follows:

[0112] ω j,1 =1+g j ;

[0113] ω j,2 =Y j *(1+M j );

[0114] Among them, ω j,1 is the intermediate adjustment parameter of the jth acupoint (i.e., the overall adjustment parameter), g j is the high temperature coefficient of the jth acupoint; ω j,2 is the final adjustment parameter of the jth acupoint (i.e., amplitude adjustment coefficient), M j is the sensitization weakening coefficient of the jth acupoint, Y j is the local induration influence coefficient of the j-th acupoint.

[0115] According to the intermediate adjustment parameters and final adjustment parameters of each acupoint, the electrical impedance of each acupoint can be adjusted. In an exemplary embodiment, the sub-health quantitative assessment system for depression patients based on acupoint resistance characteristics provided by this embodiment also includes an electrical impedance adjustment module, which is used to perform the following adjustment process:

[0116] For the initial electrical impedance of the jth acupoint at the bth moment, that is, the actual collected electrical impedance c j,b , then the final electrical impedance c″ of the jth acupoint at the bth moment j,b The calculation method is:

[0117] c′ j,b =c j,b *ω j,1 ;

[0118]

[0119] Among them, c j,b is the initial electrical impedance of the jth acupoint at the bth moment, c′ j,b is the intermediate electrical impedance of the jth acupoint at the bth moment, is the average value of the intermediate electrical impedance of the jth acupoint at all times, is the average value of the initial electrical impedance of the jth acupoint at all times, c″ j,b is the final electrical impedance of the jth acupoint at the bth moment.

[0120] After the above process, the final electrical impedance of each acupoint after adjustment is obtained. In subsequent applications, the final electrical impedance of each acupoint after adjustment can be used as a data reference to quantitatively evaluate the sub-health of depressed patients. In a specific application, the average values of the electrical impedance are calculated, including the average value of the electrical impedance of all acupoints (mean, M), the ratio of all yin meridians to yang meridians (yin-yang ratio, YinYangratio, Yi / Ya), the ratio of hand meridians to foot meridians (up-down ratio, U / D), and the ratio of the left meridian to the right meridian (left-right ratio, L / R).

[0121] Acupoints are divided into Yin meridians (three Yin meridians of the hand and three Yin meridians of the foot) and Yang meridians (three Yang meridians of the hand and three Yang meridians of the foot). The ratio of all Yin meridians to Yang meridians (YinYangratio, Yi / Ya) is calculated: Yin meridian Yi is equal to the ratio of the electrical impedance of all Yin meridian acupoints to the total number of Yin meridian acupoints, and Ya is equal to the ratio of the electrical impedance of all Yang meridian acupoints to the total number of Yang meridian acupoints.

[0122] Acupoints are divided into the hand meridians (the hand three yin meridians and the hand three yang meridians) and the foot meridians (the foot three yin meridians and the foot three yang meridians). The hand meridian to foot meridian ratio (up-down ratio, U / D) is calculated as follows: U for the hand meridian is equal to the ratio of the total electrical impedance of all hand meridian acupoints to the total number of hand meridian acupoints, while D for the foot meridian is equal to the ratio of the total electrical impedance of all foot meridian acupoints to the total number of foot meridian acupoints.

[0123] Acupoints are divided into left and right sides. The left-right ratio (L / R) is calculated as follows: L for the left meridians is equal to the ratio of the total electrical impedance of all left meridian acupoints to the total number of left meridian acupoints; R for the right meridians is equal to the ratio of the total electrical impedance of all right meridian acupoints to the total number of right meridian acupoints.

[0124] The range between the 30th percentile (P30) and the 70th percentile (P70) of the M value is defined as the normal physiological range. Meridian impedance values below P30 are defined as deficiency syndrome of that meridian, and values above P70 as excess syndrome. A Yi / Ya value of 0.8 to 1.2 indicates yin-yang balance, a Yi / Ya value greater than 1.2 indicates cold syndrome, and a Yi / Ya value less than 0.8 indicates heat syndrome. A U / D value of 0.8 to 1.2 indicates upper-lower balance, a U / D value greater than 1.2 indicates upper-excess and lower-deficiency, and a U / D value less than 0.8 indicates upper-deficiency and lower-excess. A L / R value of 0.8 to 1.2 indicates left-right balance, and L / R values greater than 1.2 or less than 0.8 indicate left-right meridian imbalance. For each of the above items, no treatment is performed if it is within the normal range. If any item is outside the normal range, the absolute difference from the normal range is used to determine the severity of the patient's sub-health manifestations. It should be understood that the subsequent sub-health quantitative assessment process based on the adjusted final electrical impedance of each acupoint belongs to the existing technology, such as the specific process given in the paper entitled "Clinical Study on the Resistance Characteristics of Meridian Acupoints in Sub-Healthy States".

[0125] It should be understood that the focus of the present invention is the process of adjusting the electrical impedance of each acupoint, and is not limited to the subsequent sub-health quantitative assessment process based on the final electrical impedance after adjustment of each acupoint. In addition to the quantitative assessment process provided above, the implementer can also select other quantitative assessment processes according to actual needs. The present invention is not constrained by the subsequent sub-health quantitative assessment process based on the final electrical impedance after adjustment of each acupoint.

[0126] It should be noted that the order in which the embodiments of the present invention are described above is for illustrative purposes only and does not necessarily represent the superiority or inferiority of the embodiments. The processes depicted in the accompanying drawings do not necessarily require the specific order or sequential order shown to achieve the desired results. In certain embodiments, multitasking and parallel processing are also possible or may be advantageous.

[0127] The various embodiments in this specification are described in a progressive manner, and the same or similar parts between the various embodiments can be referred to each other. Each embodiment focuses on the differences from other embodiments.

Claims

1. A quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics, characterized by: include: A high temperature region acquisition module is used to determine the high temperature region of the body of the depressed patient; the high temperature region is obtained by the high temperature characteristics of each acupoint, and the high temperature characteristics are obtained by the temperature of each acupoint; a local induration influence coefficient acquisition module, configured to obtain the local induration influence coefficient of each acupoint based on the difference between the tissue hardness characteristics of each acupoint and the tissue hardness characteristics of the acupoints in other areas outside the high temperature area; The sensitization and weakening coefficient acquisition module is used to obtain the electrical impedance change sequence before and after acupoint stimulation of each acupoint, and obtain the sensitization and weakening coefficient of each acupoint based on the residual fluctuation of the corresponding fitting line and the overall change degree of the electrical impedance; The adjustment parameter acquisition module is used to obtain the electrical impedance adjustment parameters of each acupoint according to the high temperature characteristics, local nodule influence coefficient and sensitization weakening coefficient of each acupoint.

2. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, characterized in that: The process of obtaining the local induration influence coefficient includes: Obtaining an average value of tissue hardness characteristics of all acupuncture points in areas other than the high temperature area; The difference between the tissue hardness characteristic of the target acupoint and the average value of the tissue hardness characteristic is obtained to obtain the local induration influence coefficient of the target acupoint; the target acupoint is any acupoint.

3. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, characterized in that: The process of obtaining the overall change degree of the electrical impedance includes: Acquiring an overall electrical impedance change sequence, wherein the overall electrical impedance change sequence is obtained by splicing the electrical impedance change sequence before acupoint stimulation and the electrical impedance change sequence after acupoint stimulation; A fitting straight line of the overall electrical impedance change sequence is obtained, where the overall electrical impedance change degree is the absolute value of the slope of the fitting straight line.

4. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, characterized in that: The process of obtaining the sensitization weakening coefficient includes: Obtaining a first residual sequence and a second residual sequence; the first residual sequence is a residual sequence of an electrical impedance change sequence of a target acupoint before acupoint stimulation and a fitted straight line, and the second residual sequence is a residual sequence of an electrical impedance change sequence of a target acupoint after acupoint stimulation and a fitted straight line, wherein the target acupoint is any acupoint; Obtaining a variance difference between the second residual sequence and the first residual sequence; The sensitization weakening coefficient of the target acupuncture point is obtained according to the overall change degree of the electrical impedance of the target acupuncture point and the variance difference.

5. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 4, characterized in that: Obtaining the sensitization weakening coefficient of the target acupoint according to the overall change degree of the electrical impedance of the target acupoint and the variance difference includes: The product of the overall change degree of the electrical impedance and the variance difference is calculated, and negative correlation normalization is performed to obtain the sensitization weakening coefficient.

6. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, characterized in that: The electrical impedance adjustment parameters of the target acupuncture point include the intermediate adjustment parameters and the final adjustment parameters of the target acupuncture point; the target acupuncture point is any acupuncture point; The intermediate adjustment parameter of the target acupoint is equal to the sum of the value 1 and the high temperature coefficient of the target acupoint; wherein, if the target acupoint is in the high temperature area, the high temperature coefficient of the target acupoint is the average value of the high temperature characteristics of each acupoint in the high temperature area; if the target acupoint is not in the high temperature area, the high temperature coefficient of the target acupoint is 0; The final adjustment parameter of the target acupoint is equal to the product of the local induration influence coefficient of the target acupoint and the sensitization increase coefficient of the target acupoint, and the sensitization increase coefficient of the target acupoint is equal to the sum of the value 1 and the sensitization weakening coefficient of the target acupoint.

7. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 6, characterized in that: The sub-health quantitative assessment system for depression patients based on acupoint resistance characteristics further includes an electrical impedance adjustment module, which is used to perform the following adjustment process: c′ j,b =c j,b *oh j,1 ; Among them, c j,b is the initial electrical impedance of the jth acupoint at the bth moment, ω j,1 is the intermediate adjustment parameter of the jth acupoint, c′ j,b is the intermediate electrical impedance of the jth acupoint at the bth moment, is the average value of the intermediate electrical impedance of the jth acupoint at all times, is the average value of the initial electrical impedance of the jth acupoint at all times, ω j,2 is the final adjustment parameter of the jth acupoint, c″ j,b is the final electrical impedance of the jth acupoint at the bth moment.

8. The quantitative assessment system for sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, characterized in that: The process of obtaining the high temperature characteristics includes: Obtaining a first difference of a target acupuncture point, where the first difference is a difference between a temperature of the target acupuncture point and a preset priori temperature of the target acupuncture point; the target acupuncture point is any acupuncture point; Obtaining a second difference of the target acupuncture point, where the second difference is a difference between the temperature of the target acupuncture point and an average temperature of all acupuncture points; The first difference and the second difference are integrated to obtain the high temperature characteristic of the target acupuncture point.

9. The system for quantitatively assessing sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, wherein: The process of obtaining the high temperature area includes: The high temperature characteristics of each acupoint are compared with a preset high temperature characteristic threshold, and the area formed by adjacent acupoints in the acupoints corresponding to the high temperature characteristics greater than the preset high temperature characteristic threshold is regarded as a high temperature area.

10. The system for quantitatively assessing sub-health of depressed patients based on acupoint resistance characteristics according to claim 1, wherein: The tissue hardness characteristic is the Young's modulus value.

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