Child rat medicinal liquor for treating burns and scalds

Abstract

The invention relates to a child rat medicinal liquor for treating burn and scald, and the core scheme is as follows: taking about 8 (100g) living child rats with unopened eyes, disinfecting step by step with 500g of 60-degree white spirit, draining, and soaking for 180 days in a sealed manner to obtain thick medicinal liquor. The method is technically characterized in that a living biological material releases active components during long-time light-shielding aging to form a high-viscosity liquid medicine. After the medicinal liquor is externally applied to burn and scald wounds, the wound reaction can be remarkably relieved, and no pain or itching feeling exists in the whole process; the wound convergence can be effectively promoted by three times of application every day, and the typical performance is that physiological scabbing is realized within 72 hours of continuous use. The traditional medicinal liquor preparation mode is broken through, and three clinical pain points of wound pain control, healing speed and operation convenience are synchronously solved through three innovations of living body treatment, Baijiu conversion and aging control.

Description

Technical Field

[0001] The invention relates to the technical field of scald medicines, in particular to a rat medicine wine for treating burns and scalds. Background Art

[0002] In the clinical treatment of burns and scalds, conventional topical medications generally have three contradictions:

[0003] The contradiction between analgesic needs and irritation effects: Although commercially available ointments containing ingredients such as alcohol and benzocaine have analgesic effects, high-concentration solvents can easily cause stinging or burning sensations on the wound surface (such as phenolic preparations), aggravating the patient's pain;

[0004] Conflict between anti-infection and delayed healing: while antibiotic ointments inhibit bacteria, they also delay epithelial cell migration (such as silver sulfadiazine), leading to delayed scab formation;

[0005] Conflict between physical barrier and breathability: Although occlusive dressings such as Vaseline can isolate pollution, they hinder oxygen exchange in the wound and easily induce maceration and even secondary infection.

[0006] Existing animal-derived medicinal wine technologies (such as snake and scorpion-infused wines) mostly focus on anti-rheumatic or internal use, and their application to wounds has obvious drawbacks:

[0007] Insufficient release of active substances: Traditional processes use rigor mortis animals, which results in loss of cell membrane permeability and a dissolution rate of less than 5% of bioactive factors.

[0008] Risk of residual irritation: When animals with unremoved internal organs are soaked in alcohol, their bodies release pain- and itching-inducing substances such as histamine and cadaverine.

[0009] Unsuitable application form: The medicinal wine is too fluid (viscosity < 50cp) and cannot form a stable covering layer on the wound surface, requiring frequent reapplication.

[0010] Therefore need a kind of rat medicine wine that is used to treat burns and scalds to solve the above problems. Summary of the Invention

[0011] In order to solve the problems of the prior art, the present invention provides a rat-derived medicinal wine for treating burns and scalds. By treating rat-derived mice at a specific life stage and controlling the time of treatment, a substantial improvement in the therapeutic efficacy is achieved.

[0012] In order to solve the above technical problems, the present invention is achieved through the following technical solutions: In the first aspect, a rat medicine wine for treating burns and scalds is prepared by the following method:

[0013] Take a litter of live, eye-opening newborn mice, weighing 80-120 grams in total;

[0014] Disinfect the surface of the rats with 250±20ml of 60% alcohol and drain.

[0015] Place the drained offspring into a sterilized glass container;

[0016] Add 250±20ml of 60% alcohol to completely immerse the rats;

[0017] Seal and keep away from light and soak for 150-210 days until the liquid becomes thick.

[0018] In this application, after being sealed and soaked until it becomes thick for half a year, this medicinal wine, when applied externally to burn and scald wounds, can significantly relieve wound discomfort reactions, and patients do not feel pain or itching during use. By spraying or applying the medicinal wine to the affected area three times a day, it can be observed that the wound exudate is reduced and the tissue repair process is accelerated. After three days of continuous use, a protective scab is formed on the wound, achieving the natural reconstruction of the physical barrier. This effect is due to the medicinal wine directly acting on the damaged skin surface, promoting the stable transition of the wound to the healing stage.

[0019] In a specific embodiment of the first aspect, the offspring is a newborn mammalian rodent;

[0020] There are 6-10 mice in each litter.

[0021] In a second aspect, a method for preparing a rat medicine wine for treating burns and scalds comprises the following steps:

[0022] S1: Live offspring are disinfected with white wine and then drained;

[0023] S2: Place the sterilized rats and liquor in a sealed container at a weight ratio of 1:5±0.5;

[0024] S3: Soak in a dark environment at 25±5℃ for 180±30 days.

[0025] In a third aspect, a method for treating burns and scalds using a rat medicine wine in the preparation of a burn and scald external application medicine is provided, wherein the thick wine is directly sprayed or applied to the wound surface with a cotton swab;

[0026] Apply 2-4 times daily;

[0027] Continue to use until the wound scabs over.

[0028] In a specific embodiment of the first aspect, there is no pain or itching reaction on the wound after the medication is applied;

[0029] The treatment cycle is 3±1 days.

[0030] The beneficial effects of the present invention are:

[0031] 1. Through the long-term reaction between live mice and high-concentration liquor, a breakthrough is made in the traditional preparation model of medicinal wine for trauma. Living tissue is infiltrated by liquor in a closed environment, prompting it to fully release bioactive substances, forming a unique thick medicinal solution. While completely retaining the bioactive components, this process completely avoids the risk of exogenous contamination, and ensures that the final product has stable physical properties (the fluidity automatically decreases to a suitable viscosity for coating). Compared with conventional alcohol extracts, this medicinal wine forms a breathable protective film when applied directly to the wound surface, which not only isolates the wound from environmental stimuli, but also maintains the physiological moist environment of the wound surface, creating favorable conditions for tissue repair. DETAILED DESCRIPTION

[0032] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0033] A rat medicine wine used to treat burns and scalds.

[0034] 1. Raw Materials Preparation

[0035] Rats: Obtain a litter of newly born, eyeless rats (about 8, total weight about 100 grams);

[0036] Liquor: 500 grams (half a pound) of 60-proof liquor.

[0037] 2. Disinfection

[0038] Place the live rats in a clean container and pour 250g of 60% alcohol into the container to rinse and disinfect the surface.

[0039] Let it sit and drain until there is no wine residue on the surface of the rat (about 10 minutes).

[0040] 3. Bottle soaking

[0041] Take a transparent glass bottle (capacity ≥ 1 liter) that has been sterilized at high temperature;

[0042] Transfer the drained live offspring intact into a glass bottle;

[0043] Pour the remaining 250 grams of 60-proof liquor into the bottle (the total amount of liquor is 500 grams);

[0044] Seal the bottle immediately.

[0045] 4. Storage and aging

[0046] Place the sealed glass bottle in a cool, dark place (such as inside a cupboard);

[0047] Keep it in a standing position and soak for 180 days (half a year) and do not open the package during this period.

[0048] 5. Medicinal wine is used

[0049] After the soaking period is over, open the bottle and confirm that the medicinal wine is thick (the fluidity is significantly reduced and the color is darker);

[0050] Use sterilized tweezers to filter out the residue and keep the thick medicinal wine for later use.

[0051] 6. Usage

[0052] Applicable symptoms: mild to moderate burns and scald wounds;

[0053] Steps:

[0054] Spray the medicinal wine directly onto the wound, or use a sterilized cotton swab to dip the medicinal wine and apply it evenly;

[0055] The wound surface did not cause pain or itching after application of the medicine;

[0056] Frequency of use: once in the morning, noon, and evening (3 times a day);

[0057] Treatment period: 3 consecutive days (in most cases, the wound will form a complete scab). Example: Preparation of Rat Medicinal Wine and its application in treating burns

[0058] 1. Raw material ratio

[0059] Components Specifications and dosage Live rats Newly born with eyes closed, 1 litter (about 8 puppies, total weight 100g) 60% alcohol liquor Total 500g (half a pound)

[0060] 2. Preparation Process

[0061] Step 1 Pretreatment of offspring

[0062] Place the live rat in a sterilized beaker and pour in 250g of liquor to rinse the surface impurities; let it stand for 10 minutes and drain until no liquor drips.

[0063] Step 2: Soaking and aging

[0064] Take a 1L brown glass bottle and sterilize it at 120℃ for 30 minutes;

[0065] Transfer the drained offspring into the bottle and add the remaining 250g of liquor (the liquid level is enough to completely submerge the offspring); tighten the bottle cap, wrap it with aluminum foil to avoid light, and place it in a cool place (ambient temperature 25±3℃).

[0066] Step 3: Post-ripening

[0067] Soak for 180 days (calculated from the date of sealing the bottle);

[0068] Open the bottle and confirm that the medicinal wine is thick amber in color (the fluidity is close to syrup).

[0069] Key control points: Use living animals as medicine (not after slaughter), use white wine in divided doses (half a pound for disinfection + half a pound for soaking), strictly avoid light (no light throughout the process).

[0070] 3. Efficacy verification (based on real cases)

[0071] Case Overview

[0072] Patient: A 35-year-old male with superficial second-degree hot oil burn on the right forearm (wound area approximately 3 cm × 4 cm, ruddy base with blisters);

[0073] The patient was seen 2 hours after the injury and the blister was drained after debridement.

[0074] Medication regimen

[0075] Take the thick medicinal wine prepared in Example 1;

[0076] Usage: Dip a sterilized cotton swab in the medicinal wine and apply it evenly and thinly on the wound surface (no friction);

[0077] Frequency: once every day at 8:00 am, 2:00 pm, and 8:00 pm (3 times a day);

[0078] Treatment course: 3 consecutive days of use.

[0079] Observation results

[0080]

[0081] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.

Claims

1. A rat medicine wine for treating burns and scalds, characterized in that: Prepared by the following method: Take a litter of live, eye-opening newborn mice, weighing 80-120 grams in total; Disinfect the surface of the rats with 250±20ml of 60% alcohol and drain. Place the drained offspring into a sterilized glass container; Add 250±20ml of 60% alcohol to completely immerse the rats; Seal and keep away from light and soak for 150-210 days until the liquid becomes thick.

2. The rat medicine wine for treating burns and scalds according to claim 1, characterized in that: The offspring is a newborn mammal or rodent; There are 6-10 mice in each litter.

3. A method for preparing rat medicine wine for treating burns and scalds, characterized in that: The following steps are involved: S1: Live offspring are disinfected with white wine and then drained; S2: Place the sterilized rats and liquor in a sealed container at a weight ratio of 1:5±0.5; S3: Soak in a dark environment at 25±5℃ for 180±30 days.

4. A method for treating burns and scalds using a rat medicine wine in the preparation of a burn and scald external application medicine, characterized in that: Spray the thick medicinal wine directly or apply it on the wound with a cotton swab; Apply 2-4 times daily; Continue to use until the wound scabs.

5. The use of the rat medicine wine for treating burns and scalds according to claim 4 in preparing a burn and scald external application medicine, characterized in that: There is no pain or itching reaction on the wound after medication; The treatment cycle is 3±1 days.

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