Bone micropunch positioning and drug delivery guide plate

Abstract

The invention belongs to the field of dental instruments, and particularly relates to a bone micropunch positioning and drug delivery guide plate. Comprising a guide plate body, the guide plate body is provided with a buckling part matched with an invisible tooth socket, and the guide plate body is detachably connected with the invisible tooth socket through the buckling part; the guide plate body is provided with a plurality of array penetrating positioning holes which are used for guiding surgical instruments to perform bone micro-perforation; the positioning holes are communicated with overflow channels in the guide plate body, and the overflow channels are used for discharging cooling liquid and reducing the local temperature during drilling and grinding; a medicine containing groove is further formed in the side, making contact with gingiva, of the guide plate body. By adopting the device, the accuracy, the safety and the treatment effect of a bone micro-perforation operation can be improved.

Description

Technical Field

[0001] The invention belongs to the field of dental instruments, in particular to a bone micro-perforation positioning and drug delivery guide plate. Background Art

[0002] In the field of orthodontic treatment, bone microperforation technology has received widespread attention in recent years as an auxiliary means of accelerating tooth movement. This technology stimulates local bone metabolism by making tiny perforations in specific areas of the alveolar bone, thereby accelerating the movement of teeth under orthodontic forces and shortening the treatment cycle. However, existing bone microperforation technology has some drawbacks in clinical application:

[0003] Due to the lack of precise positioning tools, existing technologies are prone to deviations when determining the perforation position, which may accidentally injure important anatomical structures such as tooth roots, neurovascular bundles, and increase surgical risks. In addition, manual operation makes it difficult to accurately control the depth and angle of the perforation, resulting in a lack of uniformity and predictability in the stimulation effect. This lack of precision will affect the safety and therapeutic effect of the operation. Traditional bone microperforation surgery usually requires a larger surgical incision and a deeper perforation depth to ensure the effect of stimulating bone metabolism. However, this method increases the degree of tissue damage, leading to increased complications such as postoperative swelling and pain, and prolonging the patient's recovery time. In addition, after bone microperforation, local application of drugs that promote bone metabolism is often required to enhance the therapeutic effect, but due to the lack of precise drug delivery methods, the drug easily diffuses to the tissues around the perforation, resulting in a decrease in local drug concentration and unstable therapeutic effect.

[0004] In summary, existing bone microperforation techniques suffer from issues such as insufficient precision, excessive trauma, and unstable efficacy, which limit their effectiveness and patient comfort in orthodontic treatment. Therefore, a structure that can improve surgical precision, reduce tissue trauma, and achieve precise drug delivery is urgently needed. Summary of the Invention

[0005] To address these issues, the present invention provides a bone microperforation positioning and drug delivery guide. The guide is customized using the patient's 3D imaging data to match the structure of the invisible braces, ensuring precise alignment of the positioning holes with the target alveolar bone perforation area, ensuring precise guidance of surgical instruments. Furthermore, the guide is equipped with overflow channels and drug receiving grooves for draining coolant and directly introducing drugs. This device can improve the accuracy, safety, and therapeutic effectiveness of bone microperforation procedures.

[0006] In order to achieve the above objectives, the present invention specifically adopts the following technical means:

[0007] A bone microperforation positioning and drug delivery guide comprises a guide body, the guide body being provided with a snap-fit ​​portion that matches an invisible brace and is detachably connected to the invisible brace through the snap-fit ​​portion; the guide body being provided with a plurality of positioning holes extending through an array for guiding surgical instruments for bone microperforation; the positioning holes being connected to an overflow channel inside the guide body, the overflow channel being used to discharge coolant and reduce the local temperature during drilling and grinding; and a drug receiving groove being further provided on the side of the guide body that contacts the gums.

[0008] Furthermore, a buckling hole is provided in the buckling portion, and the buckling portion and the braces protrusion on the invisible braces form a stable connection through a plug-in structure.

[0009] Furthermore, the invisible braces and the braces protrusions are integrally formed.

[0010] Furthermore, the thickness of the guide plate body is 2 mm, the diameter of the positioning holes is 0.5 to 1.0 mm, and they are evenly distributed vertically 5 mm below the intergingival papilla.

[0011] Furthermore, the overflow channel is a pipe structure, which is connected to the positioning hole and extends to the edge of the guide plate body, and is used to discharge coolant to reduce the local temperature during drilling and grinding.

[0012] Furthermore, the microneedle patch is fixed to the micro-perforation through the drug receiving groove of the guide plate body, so as to slowly release the drug and introduce it into the micro-perforation.

[0013] Furthermore, the position of the positioning hole is planned based on the patient's three-dimensional imaging data, maintaining a safe distance from the tooth root, and the positioning error is less than 0.5 mm.

[0014] Compared with the prior art, the present invention has the following beneficial technical effects:

[0015] The present invention achieves a removable connection between the guide plate and the invisible braces through a snap-fitting portion on the guide plate body. The positioning holes are planned based on the patient's 3D imaging data, ensuring precise alignment with the target area for alveolar bone drilling. The positioning holes ensure precise guidance of surgical instruments while maintaining a safe distance from the tooth root, with positioning errors controlled to within 0.5mm.

[0016] Thanks to the precise positioning holes and the guide plate's 2mm thickness, this device allows for more precise surgical procedures, reducing the incision and perforation depth. Compared to traditional bone microperforation techniques, which require larger incisions and deeper perforations, this device reduces tissue damage, thereby lowering the incidence of complications such as postoperative swelling and pain, and shortening patient recovery time.

[0017] The side of the guide body that contacts the gums is equipped with a drug-receiving groove. This structure secures the microneedle patch to the microperforations, enabling sustained drug release and direct delivery into the microperforations. This design ensures sustained, localized, high-concentration drug action, preventing drug diffusion into surrounding tissues and improving the stability and reliability of the treatment.

[0018] The overflow channel inside the guide body connects to the positioning hole and extends to the edge of the guide, effectively draining coolant and reducing local temperatures during drilling. This prevents tissue damage from overheating, further improving surgical safety and providing additional protection during micro-perforation procedures. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the combination of a guide plate and invisible braces in a specific embodiment of the present invention;

[0020] Figure 2 It is a schematic diagram of a guide plate in a specific embodiment of the present invention;

[0021] Figure 3 is another schematic diagram of a guide plate in a specific embodiment of the present invention;

[0022] Figure 4 is a cross-sectional view of a guide plate in a specific embodiment of the present invention;

[0023] Figure 5 is a schematic diagram of a fastening portion in a specific embodiment of the present invention;

[0024] The numbers in the figure are: 1, invisible braces; 11, braces protrusion; 2, guide plate body; 21, buckling part; 22, recessed hole; 23, drug receiving groove; 24, positioning hole; 25, overflow channel. DETAILED DESCRIPTION

[0025] The following describes the embodiments of the present invention by means of specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and the details in this specification can also be modified or changed in various ways based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that the illustrations provided in the following embodiments are only schematic illustrations of the basic concept of the present invention, and the following embodiments and features in the embodiments can be combined with each other without conflict.

[0026] Among them, the accompanying drawings are only for illustrative purposes and represent only schematic diagrams rather than actual pictures, and should not be understood as limiting the present invention. In order to better illustrate the embodiments of the present invention, certain parts of the accompanying drawings may be omitted, enlarged or reduced, and do not represent the dimensions of actual products. For those skilled in the art, the omission of certain well-known structures and their descriptions in the accompanying drawings is understandable.

[0027] See also Figure 1 The present invention proposes a bone microperforation positioning and drug delivery guide, which is engaged with an invisible brace 1. The invisible brace 1 is provided with a brace protrusion 11, and the guide body 2 is provided with a snap-fit ​​portion 21 that matches the brace protrusion 11. The snap-fit ​​structure between the snap-fit ​​portion 21 and the brace protrusion 11 forms a stable connection between the guide body 2 and the invisible brace 1. The invisible brace and the brace protrusion 11 are integrally formed, and their elastic modulus is used to achieve wrapping of the dentition, ensuring that the guide body 2 can still fit tightly despite the dynamic displacement of the teeth during orthodontic correction.

[0028] See also Figure 2 and Figure 3 The guide body 2 is provided with 5 rows of through positioning holes 24, the diameter of the positioning holes 24 is 0.5 to 1.0 mm, and they are evenly distributed vertically 5 mm below the gingival papilla, for guiding surgical instruments to perform bone micro-perforation. The thickness of the guide body 2 is 2 mm, and it is used in conjunction with the limiting device of the surgical instrument to ensure precise control of the perforation depth. The position of the positioning hole 24 is planned based on the patient's three-dimensional imaging data, and is kept at a safe distance from the tooth root and neurovascular bundle through computer-aided design, with a positioning error of less than 0.5 mm. Figure 3 As shown, a drug receiving groove 23 is provided on the side of the guide plate body 2 that contacts the gums, for fixing the microneedle patch to achieve sustained release and targeted delivery of the drug.

[0029] See also Figure 4 The guide body 2 is internally provided with an overflow channel 25, a pipe structure that connects to the positioning hole 24 and extends to the edge of the guide body 2. This overflow channel 25 is used to discharge coolant, reducing the local temperature during drilling and milling, preventing tissue damage from overheating and improving surgical safety. During surgery, coolant enters the overflow channel 25 through the positioning hole 24, effectively controlling the temperature of the surgical area.

[0030] See also Figure 5 The fastening portion 21 is provided with a fastening hole, which forms a stable connection with the brace protrusion 11 on the invisible brace 1 through a plug-in structure. Multiple fastening portions 21 engage with the brace protrusion 11 of the invisible brace 1, ensuring easy assembly and preventing rotational displacement, meeting surgical precision requirements. This structure allows the guide body 2 to be detachably connected to the invisible brace 1. After the procedure, the guide body 2 can be removed and a microneedle patch inserted for bone microperforation drug delivery.

[0031] In some embodiments, the guide body 2 is manufactured in sections based on the surgical area, including anterior and bilateral posterior sections, to better fit the surgical area and ensure surgical precision. The anterior section can be placed on the buccal and gingival side of the lateral incisors, while the posterior section can be placed between the first and second premolars, and between the first and second molars.

[0032] In some embodiments, the microneedle patch drug is secured to the microperforations via the drug-receiving groove 23 of the guide body 2. After surgery, the reserved space in the drug-receiving groove 23 is used to assemble the microneedle patch, enabling targeted drug delivery without flap opening. Simply inserting the microneedle patch into the drug-receiving groove 23 allows for sustained release of the drug directly into the microperforations, preventing drug diffusion into surrounding tissues, enhancing local efficacy, and further accelerating tooth movement.

[0033] In this embodiment, the design of the guide body 2 is personalized based on the patient's three-dimensional imaging data (CBCT) combined with intraoral scanning. Through computer-aided design, the distribution of the positioning holes 24 strictly corresponds to the target area of ​​the alveolar bone, ensuring precise guidance of the surgical instrument. During the design process, an algorithm optimizes the perforation site, avoiding key anatomical structures such as the tooth root and neurovascular bundle, and controlling the positioning error to within 0.5mm. The guide body 2 is made of a biocompatible light-curing 3D printing resin with excellent biocompatibility. It can be sterilized at high temperature and high pressure and reused, reducing treatment costs.

[0034] In this embodiment, the guide plate body 2 is used in conjunction with the invisible braces 1 to address the difficulty and slowness of anterior tooth intrusion during invisible braces treatment. This optimizes tooth movement through precise bone microperforation. The guide plate body 2 is stably connected to the brace protrusions 11 on the invisible braces 1 via a snap-fitting portion 21. This allows for the installation of the surgical guide without replacing the patient's existing braces, enhancing treatment efficiency. After surgery, the invisible braces 1 continue to be worn until the corrective phase is complete, achieving a seamless integration of orthodontic treatment and bone microperforation technology.

[0035] The process of using this device is as follows:

[0036] First, the patient undergoes an oral scan and cone-beam computed tomography (CBCT) to obtain three-dimensional images of the teeth and alveolar bone, providing the basis for subsequent personalized design. Based on the oral scan data, a one-piece invisible brace with protrusions 11 is designed. Once the design is complete, the invisible brace is manufactured using 3D printing technology. The material used has appropriate elasticity to adapt to the dynamic movement of teeth during orthodontic treatment.

[0037] The guide body 2 is designed based on invisible braces and CBCT data, ensuring precise alignment of its positioning holes with the micro-perforations in the alveolar bone. The guide is manufactured using stereolithography 3D printing technology and biocompatible materials to ensure safety and durability.

[0038] Before the procedure begins, the doctor places the pre-made invisible braces on the patient's teeth to ensure a close fit, laying the foundation for the subsequent fixation of the guide plate. The guide plate is connected to the protrusions on the invisible braces through the snap-fitting part, ensuring a stable fixation in the patient's mouth and providing precise positioning support for the procedure.

[0039] The doctor guides the drill needle through the positioning hole 24 on the guide plate to perform micro-perforation of the bone, ensuring that the perforation position avoids key structures such as the tooth root and nerves and blood vessels. During the drilling process, the overflow channel 25 inside the guide plate is connected to the positioning hole 24 for draining the coolant.

[0040] After the bone microperforation surgery is completed, the doctor removes the guide plate body 2 from the invisible braces and fixes the microneedle patch to the microperforation through the drug receiving groove 23 on the guide plate body 2. The guide plate body 2 is reinstalled on the invisible braces 1 to complete the targeted drug delivery.

[0041] The above describes specific embodiments of the invention. It should be understood that the invention is not limited to the specific embodiments described above. Devices and structures not described in detail should be understood to be implemented in a common manner in the art. Those skilled in the art may make various modifications, variations, or simple deductions, deformations, or substitutions within the scope of the claims, without affecting the essence of the invention.

Claims

1. A bone microperforation positioning and drug delivery guide, characterized in that: The invention comprises a guide plate body (2), wherein the guide plate body (2) is provided with a snap-fit ​​portion (21) matching with the invisible braces (1), and is detachably connected to the invisible braces (1) through the snap-fit ​​portion; the guide plate body (2) is provided with a plurality of positioning holes (24) extending through an array, which are used to guide surgical instruments to perform bone micro-perforation; the positioning holes (24) are communicated with an overflow channel (25) inside the guide plate body (2), and the overflow channel (25) is used to discharge cooling liquid to reduce the local temperature during drilling and grinding; the side of the guide plate body (2) in contact with the gum is also provided with a drug receiving groove (23).

2. The bone microperforation positioning and drug delivery guide according to claim 1, characterized in that: A snap-fit ​​hole is provided in the snap-fit ​​portion (21), and the snap-fit ​​portion (21) and the brace protrusion (11) on the invisible brace (1) form a stable connection through a plug-in structure.

3. The bone microperforation positioning and drug delivery guide according to claim 1, characterized in that: The invisible braces (1) and the braces protrusion (11) are integrally formed.

4. The bone microperforation positioning and drug delivery guide according to claim 1, characterized in that: The thickness of the guide plate body (2) is 2 mm, the diameter of the positioning holes (24) is 0.5-1.0 mm, and they are evenly distributed vertically 5 mm below the gingival papilla.

5. The bone microperforation positioning and drug delivery guide according to claim 1, characterized in that: The overflow channel (25) is a pipe structure, communicated with the positioning hole (24) and extending to the edge of the guide plate body (2), and is used for discharging coolant to reduce the local temperature during drilling and grinding.

6. The bone microperforation positioning and drug delivery guide according to claim 1, characterized in that: The microneedle patch is fixed to the microperforation through the drug receiving groove (23) of the guide plate body (2) and is used for slowly releasing the drug and introducing it into the microperforation.

7. The bone microperforation positioning and drug delivery guide according to claim 1, characterized in that: The position of the positioning hole (24) is planned based on the patient's three-dimensional imaging data, maintaining a safe distance from the tooth root, and the positioning error is within a range of less than 0.5 mm.

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