Establishment method and application of UHPLC fingerprint of traditional Chinese medicine composition
The UHPLC fingerprinting method addresses the shortcomings in quality control of traditional Chinese medicine (TCM) compositions, enabling comprehensive quality control of compositions containing herbs such as Drynaria fortunei, Cibotium barometz, Ligustrum lucidum, Spatholobus suberectus, Pyrola rotundifolia, and Achyranthes bidentata. This method boasts high precision and stability, making it suitable for the systematic and refined management of TCM pharmaceutical quality standards.
CN120703285BActive Publication Date: 2026-05-12SHAANXI UNIV OF CHINESE MEDICINE
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHAANXI UNIV OF CHINESE MEDICINE
- Filing Date
- 2025-07-17
- Publication Date
- 2026-05-12
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Figure CN120703285B_ABST
Abstract
The UHPLC fingerprint spectrum establishment method and application of the traditional Chinese medicine composition of the present application, rhizoma drynariae 15 parts, 12 parts of dracaena, 10 parts of ligustrum lucidum aiton, 10 parts of caesalpinia, 10 parts of pyrola calliantha and 10 parts of radix cyathulae are made into traditional Chinese medicine composition water decoction, vacuum freeze drying is prepared by vacuum concentration, freeze-dried powder, the quality control of traditional Chinese medicine composition is carried out by establishing UHPLC fingerprint spectrum, and the content of multiple index components of the traditional Chinese medicine composition is determined under the same chromatographic condition, and the quantity value transmission relationship of multiple index components is further determined, the quality control from single object to "composition-herb" whole chain quality monitoring is realized, and the comprehensiveness and effectiveness of quality control are significantly improved.
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