Sealing device, reagent storage device and sample analyzer
By installing a sealing device on the reagent compartment and using a drive device to control the sliding of the cover to close the liquid outlet, the problem of the reagent compartment's refrigeration temperature not meeting the standard is solved, and the airtightness and refrigeration effect of the reagent compartment are maintained.
Patent Information
- Application Number
- CN202410496497.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-23
- Publication Date
- 2025-10-24
AI Technical Summary
The reagent compartment of existing photo-induced chemiluminescence detectors has an open dispensing port, which causes reagents to be exposed to air for a long time, resulting in substandard refrigeration temperatures and affecting reagent quality.
Design a sealing device that controls the cover to slide between a first position and a second position via a drive device. When no liquid is being dispensed, the cover closes the dispensing port to ensure the airtightness of the reagent compartment; when liquid is being dispensed, the dispensing port is opened to allow the reagent needle to enter.
To effectively maintain the refrigeration effect of the reagent compartment, avoid substandard refrigeration temperature, prevent reagent contamination and dilution, and ensure reagent quality.
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Figure CN120828971A_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of medical equipment, in particular to a sealing device, a reagent storage device and a sample analyzer. BACKGROUND
[0002] When analyzing blood, urine or other tissue fluid samples, biochemical automatic analyzers and immune automatic analyzers are usually used. These instruments generally add reagents to the sample, and then measure the characteristics, chemical composition and concentration of the sample by certain means after the reagent reacts with the sample. The reagent usually needs to be refrigerated.
[0003] In related technologies, a photochemical luminescence detector includes a reagent bin for storing reagents. The inside of the reagent bin provides a low-temperature environment for placing a reagent bottle. The top of the reagent bin is usually provided with an open liquid taking port opposite to the reagent bottle opening, so that a reagent needle can take reagents in the reagent bottle. However, the inside of the reagent bottle is in communication with the environment outside the reagent bin through the bottle opening and the liquid taking port, so that the reagents are exposed to the air for a long time, which may cause the refrigeration temperature of the reagent bin to be out of standard. SUMMARY
[0004] To solve or partially solve the problems in the related art, the present application provides a sealing device, a reagent storage device and a sample analyzer, which can seal the liquid taking port when the liquid is not taken, thereby ensuring the refrigeration effect of the reagent bin on the reagents.
[0005] The first aspect of the present application provides a sealing device, which is used in a reagent bin provided with a liquid taking port. The sealing device comprises a cover body provided with an opening, the cover body being used for sliding connection with the reagent bin; a driving device for driving the cover body to slide back and forth between a first position and a second position relative to the reagent bin; when the cover body is located at the first position, the opening is staggered with the liquid taking port, so that the cover body can seal the liquid taking port; when the cover body is located at the second position, the opening is arranged opposite to the liquid taking port.
[0006] Further, the reagent bin is provided with a plurality of liquid taking ports, and the cover body is provided with a plurality of openings. When the cover body is located at the second position, the plurality of openings are arranged in one-to-one correspondence with the plurality of liquid taking ports.
[0007] Further, the driving device is a motor or a pneumatic cylinder, which is arranged on the reagent bin and is in transmission connection with the cover body; or
[0008] The driving device comprises a driving member, a spring and a support, the driving member is connected with the reagent bin through the support, the output end of the driving member abuts against the cover, one end of the spring is connected with the support and the other end is connected with the cover; the driving member is a push-pull electromagnet or an electric push rod.
[0009] Further, the above sealing device further comprises a position sensor, which is triggered when the driving device drives the cover to move to the second position.
[0010] Further, the above sealing device further comprises a heating device arranged on the cover, the cover is provided with a plurality of openings, the heating device is in a sheet structure, the heating device is provided with a plurality of first through holes, and the plurality of first through holes are arranged one by one corresponding to the plurality of openings.
[0011] Further, the above sealing device further comprises a heat preservation cover connected with the cover, the heating device is arranged between the heat preservation cover and the cover; the heat preservation cover is provided with a plurality of second through holes, and the plurality of second through holes are arranged one by one corresponding to the plurality of first through holes.
[0012] Further, the above sealing device further comprises a temperature sensor arranged on the cover, and the temperature sensor is located at the end of the cover away from the driving device.
[0013] The bottom of the cover and the outside of the reagent bin are provided with a heat preservation layer.
[0014] Further, the above sealing device further comprises an over-temperature protector arranged on the cover, and the over-temperature protector is located on one side of the temperature sensor.
[0015] The second aspect of the present application provides a reagent storage device, comprising: the sealing device according to any one of the above solutions; a reagent bin, the reagent bin is provided with a liquid taking port, and the sealing device is arranged on the top of the reagent bin; a guide rail, the cover is slidably connected with the reagent bin through the guide rail.
[0016] The third aspect of the present application provides a sample analyzer, comprising the reagent storage device described above.
[0017] The technical scheme provided by the application can have the following beneficial effects: by arranging the sealing device on the reagent bin, when the reagent is not needed to be taken, the driving device drives the cover body to be located at the first position, the opening on the cover body is staggered with the liquid taking port, so that the cover body can seal the liquid taking port and ensure the sealing property of the reagent bin; when the reagent is taken, the driving device drives the cover body to be located at the second position, the opening is arranged opposite to the liquid taking port, so that the liquid taking needle can extend into the reagent bottle in the liquid taking port from the outside; therefore, the technical scheme provided by the application can only open the liquid taking port when the liquid is taken, and keep the liquid taking port sealed when the liquid is not needed to be taken, so that the cold storage effect of the reagent bin on the reagent can be ensured and the situation that the cold storage temperature is not up to the standard can be avoided.
[0018] It should be understood that the foregoing general description and the following detailed description are only exemplary and explanatory and are not restrictive of the application. BRIEF DESCRIPTION OF DRAWINGS
[0019] The above and other objects, features and advantages of the present application will become more apparent from the following detailed description when taken in conjunction with the accompanying drawings in which like reference characters refer to like parts throughout and in which:
[0020] Figure 1 is a structural schematic diagram of a reagent storage device shown in the embodiments of the application;
[0021] Figure 2 is an exploded schematic diagram of a reagent storage device shown in the embodiments of the application;
[0022] Figure 3 is a top view schematic diagram of a reagent storage device shown in the embodiments of the application;
[0023] Figure 4 is another top view schematic diagram of a reagent storage device shown in the embodiments of the application;
[0024] Figure 5 is an exploded schematic diagram of a sealing device shown in the embodiments of the application, in which the driving device is hidden.
[0025] LIST OF REFERENCE NUMERALS
[0026] 1-reagent bin, 11-liquid taking port, 2-sealing device, 21-cover body, 22-opening, 23-driving device, 231-driving member, 232-spring, 233-bracket, 24-position sensor, 25-heating device, 251-first through hole, 26-heat preservation cover, 261-second through hole, 27-temperature sensor, 28-over-temperature protector, 3-guide rail. DETAILED DESCRIPTION
[0027] Embodiments of the present application will be described in more detail with reference to the drawings. Although the embodiments of the present application are shown in the drawings, it is understood that the present application can be implemented in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that the present application will be thorough and complete, and will fully convey the scope of the present application to those skilled in the art.
[0028] It should be understood that, although the terms "first", "second", "third", etc. are used herein to describe various information, these information should not be limited by these terms. These terms are only used to distinguish the same type of information from each other. For example, the first information can also be referred to as the second information, and similarly, the second information can also be referred to as the first information without departing from the scope of the present application. Therefore, the features defined as "first", "second" can explicitly or implicitly include one or more of the features. In the description of the present application, the meaning of "a plurality of" is two or more, unless otherwise explicitly specified.
[0029] In the description of the present application, it should be understood that the terms "length", "width", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the purpose of facilitating the description of the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation of the present application.
[0030] Unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connection", "fixing" and the like should be understood broadly, for example, it can be fixed connection, or detachable connection or integral; it can be mechanical connection, or electrical connection; it can be directly connected, or indirectly connected through intermediate medium; it can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.
[0031] In the related art, the photochemical chemiluminescence detector includes a reagent bin for storing reagents, and a low-temperature environment is provided inside the reagent bin to place the reagent bottle. The top of the reagent bin is usually provided with an open liquid taking port opposite to the reagent bottle opening, so that the reagent needle can suck the reagent in the reagent bottle. However, the inside of the reagent bottle is in communication with the environment outside the reagent bin through the bottle opening and the liquid taking port, so that the reagent is exposed to the air for a long time, which can easily cause the refrigeration temperature of the reagent bin to be out of standard.
[0032] To solve the above problems, the application provides a sealing device, a reagent storage device and a sample analyzer, which can seal the liquid taking opening when liquid is not taken, and ensure the refrigeration effect of the reagent storage device on the reagent.
[0033] The technical solutions of the application are described in detail below with reference to the drawings.
[0034] As shown in the drawings, Figures 1 to 4 The application provides a reagent storage device, which comprises a reagent storage device 1, a sealing device 2 and a guide rail 3. The reagent storage device 1 is provided with a liquid taking opening 11. After a reagent bottle is placed in the reagent storage device 1, the bottle opening of the reagent bottle is arranged in concentric circles with the liquid taking opening 11.
[0035] The sealing device 2 comprises a cover 21 and a driving device 23. The cover 21 is provided with an opening 22, and the cover 21 is slidably connected with the reagent storage device 1. The driving device 23 is used to drive the cover 21 to slide back and forth between a first position and a second position relative to the reagent storage device 1. Figure 3 When the cover 21 is located at the first position, the opening 22 is misaligned with the liquid taking opening 11, so that the cover 21 can seal the liquid taking opening 11. Figure 4 When the cover 21 is located at the second position, the opening 22 is arranged opposite to the liquid taking opening 11.
[0036] Based on the above scheme, when the reagent is not taken, the driving device 23 drives the cover 21 to be located at the first position, and the opening 22 on the cover 21 is misaligned with the liquid taking opening 11, so that the cover 21 can seal the liquid taking opening 11, and the airtightness of the reagent storage device 1 is ensured. When the reagent is taken, the driving device 23 drives the cover 21 to be located at the second position, and the opening 22 is arranged opposite to the liquid taking opening 11, so that the liquid taking needle can extend into the reagent bottle in the liquid taking opening 11 from the outside. Therefore, the technical scheme of the application can only open the liquid taking opening 11 when the liquid is taken, and keep the liquid taking opening 11 sealed when the liquid is not taken, so that the refrigeration effect of the reagent storage device 1 on the reagent can be ensured, and the situation that the refrigeration temperature is not up to the standard can be avoided. Specifically, the cover 21 is slidably connected with the reagent storage device 1 through the guide rail 3, and the guide rail 3 is arranged between the cover 21 and the reagent storage device 1.
[0037] In the embodiment, the reagent storage device 1 is provided with a plurality of liquid taking openings 11, and the cover 21 is provided with a plurality of openings 22. When the cover 21 is located at the second position, the plurality of openings 22 are arranged in one-to-one correspondence with the plurality of liquid taking openings 11. The reagent storage device 1 is provided with a reagent bottle below each liquid taking opening 11. When the cover 21 is located at the second position, the bottle opening of the reagent bottle, the liquid taking opening 11 and the opening 22 are arranged in concentric circles, and the liquid taking needle can extend into the reagent bottle through the opening 22, the liquid taking opening 11 and the bottle opening of the reagent bottle in sequence to take liquid.
[0038] In some embodiments, the driving device 23 can be a motor driving mode or a cylinder driving mode, and the driving device 23 is arranged on the reagent bin 1 and in transmission connection with the cover 21. Specifically, when the driving device 23 is in the motor driving mode, the motor can drive the cover 21 to move back and forth through the driving of a screw rod or a screw rod in rotation, and the screw rod or the screw rod is in threaded connection with the cover 21; when the driving device 23 is in the cylinder driving mode, the piston rod of the cylinder is connected with the cover 21, and the piston rod drives the cover 21 to move back and forth when the piston rod extends and retracts.
[0039] As shown in Figures 1 to 4 , in the embodiment, the driving device 23 comprises a driving member 231, a spring 232 and a bracket 233, the driving member 231 is fixedly connected with the reagent bin 1 through the bracket 233, the output end of the driving member 231 is in abutment with the cover 21, one end of the spring 232 is connected with the bracket 233, and the other end of the spring 232 is connected with the cover 21. Optionally, the driving member 231 is a push-pull electromagnet or an electric push rod.
[0040] Specifically, the spring 232 is in a stretched state, as shown in Figure 3 , the cover 21 is kept at the first position under the action of the spring 232, so that the opening 22 is misaligned with the liquid taking opening 11, the liquid taking opening 11 is sealed, and the cold storage of the reagent bin 1 is ensured to be sealed. Figure 4 When it is necessary to suck the reagent, as shown in Figure 4 , the output end of the driving member 231 extends and abuts against the cover 21, so that the cover 21 moves to the second position against the force of the spring 232, and the cover 21 is kept at the second position after being in place, at this time, the opening 22 is concentric with the liquid taking opening 11, and the reagent needle can suck the reagent in the reagent bottle, when the reagent is sucked up, the output end of the driving member 231 is retracted, and the spring 232 drives the cover 21 to move to the first position, so as to seal the liquid taking opening 11 at the top of the reagent bin 1. As shown in Figure 3 and Figure 4 , in the embodiment, the driving device 23 is located at the left side of the cover 21, and the cover 21 can slide left and right relative to the reagent bin 1, when the cover 21 moves to the first position, the cover 21 slides left to be close to the driving device 23, and when the cover 21 moves to the second position, the cover 21 slides right to be away from the driving device 23.
[0041] In an embodiment, as shown in Figures 1 to 4 , the sealing device 2 further comprises a position sensor 24, which is triggered when the driving device 23 drives the cover 21 to move to the second position. Specifically, the position sensor 24 can be an optical sensor, which is arranged on the reagent bin 1, and is triggered when the cover 21 moves right to indicate that the cover 21 is at the second position, so that the driving device 23 stops driving the cover 21 to continue to move, and the cover 21 is kept at the second position.
[0042] The inside of the reagent bin 1 requires reagent refrigeration, and the temperature is 2-8℃. The reagent bin 1 needs to be filled with reagent on the top, and a liquid taking port 11 is arranged. The top of the reagent bin 1 will be cold due to the influence of the inside of the reagent bin 1, and the temperature is low. However, the external environment of the reagent bin 1 is about 20℃. Therefore, the hot air outside the reagent bin 1 will condense into small water droplets on the top of the reagent bin 1. The more water droplets, the more water droplets will drip into the reagent bottle from the liquid taking port 11, which will pollute and dilute the reagent.
[0043] In order to solve the problem that the condensate water generated on the top of the reagent bin 1 will pollute and dilute the reagent, in an embodiment, as shown in the figure, Figure 5 The sealing device 2 further comprises a heating device 25 arranged on the cover body 21. The heating device 25 can heat the cover body 21, so that the temperature of the cover body 21 is close to the temperature of the external environment of the reagent bin 1. In this way, the hot air outside can be prevented from condensing into water droplets on the cover body 21. When the cover body 21 is in the second position, the condensate water will not fall into the reagent bottle, which can prevent the reagent from being polluted and diluted. Specifically, the cover body 21 is provided with a plurality of openings 22, and the heating device 25 is in a sheet structure. The heating device 25 is provided with a plurality of first through holes 251, and the plurality of first through holes 251 are arranged one by one corresponding to the plurality of openings 22, so as to allow the liquid taking needle to pass through. Optionally, the heating device 25 is a resistance heating sheet.
[0044] In an embodiment, the sealing device 2 further comprises a heat preservation cover 26 connected with the cover body 21, and the heating device 25 is arranged between the heat preservation cover 26 and the cover body 21. The heat preservation cover 26 is used for covering the heating device 25 on the cover body 21, so as to prevent the heat generated by the heating device 25 from being lost. Specifically, the upper end of the cover body 21 can be provided with a cavity for mounting the heating device 25. The heating device 25 can be fixed on the cover body 21 by bolts, and the heat preservation cover 26 covers the heating device 25. The heat preservation cover 26 is provided with a plurality of second through holes 261, and the plurality of second through holes 261 are arranged one by one corresponding to the plurality of first through holes 251, so as to allow the liquid taking needle to pass through.
[0045] In an embodiment, the sealing device 2 further comprises a temperature sensor 27 arranged on the cover body 21, and the temperature sensor 27 is located at the end of the cover body 21 away from the driving device 23. The temperature sensor 27 is used for detecting the temperature of the cover body 21 after being heated by the heating device 25. The control system can control the heating device 25 to heat to a set temperature value according to the temperature detected by the temperature sensor 27. The bottom of the cover body 21 and the outside of the reagent bin 1 are provided with a heat preservation layer, which can be a heat preservation material coated. The heat preservation layer plays a role of heat preservation and heat insulation.
[0046] In an embodiment, the sealing device 2 further comprises an over-temperature protector 28 arranged on the cover 21, and the over-temperature protector 28 is located on one side of the temperature sensor 27. Specifically, when the temperature sensor 27 is damaged, the heating device 25 will continue to heat. When the temperature reaches the temperature set by the over-temperature protection, the power supply of the heating device 25 is disconnected to stop heating, thereby playing a protection role.
[0047] The application further provides a sample analyzer comprising the storage device.
[0048] The scheme of the application has been described in detail above with reference to the drawings. In the above embodiments, the description of each embodiment has its own focus, and the parts not described in detail in a certain embodiment can be referred to the relevant description of other embodiments. It should also be known by those skilled in the art that the actions and modules involved in the specification are not necessarily required by the application. In addition, it can be understood that the steps in the method of the embodiments of the application can be adjusted, combined and reduced in sequence according to actual needs, and the modules in the device of the embodiments of the application can be combined, divided and reduced according to actual needs.
[0049] The above has described the embodiments of the application, and the above description is exemplary, not exhaustive, and is not limited to the disclosed embodiments. Many modifications and changes are obvious to those skilled in the art without departing from the scope and spirit of the described embodiments. The choice of terms used herein is intended to best explain the principles of the embodiments, practical application or improvement of technology in the market, or to enable other ordinary skilled persons in the art to understand the embodiments disclosed herein.
Claims
1. A closure device, characterized in that The sealing device is used for a reagent bin provided with a liquid taking opening, and comprises: a cover body provided with an opening, the cover body being used for being slidably connected with the reagent bin; a driving device used for driving the cover body to slide back and forth between a first position and a second position relative to the reagent bin, when the cover body is located at the first position, the opening is misaligned with the liquid taking opening, so that the cover body can close the liquid taking opening, and when the cover body is located at the second position, the opening is arranged opposite to the liquid taking opening.
2. The sealing device according to claim 1, wherein: the reagent bin is provided with a plurality of liquid taking openings, and the cover body is provided with a plurality of openings, when the cover body is located at the second position, the plurality of openings are arranged in one-to-one correspondence with the plurality of liquid taking openings.
3. The sealing device according to claim 1, wherein: the driving device is a motor or a pneumatic cylinder, the driving device is arranged on the reagent bin, and the driving device is in transmission connection with the cover body; or the driving device comprises a driving member, a spring and a bracket, the driving member is connected with the reagent bin through the bracket, an output end of the driving member is in abutment with the cover body, one end of the spring is connected with the bracket, and the other end of the spring is connected with the cover body, and the driving member is a push-pull electromagnet or an electric push rod.
4. The sealing device according to claim 1, further comprising a position sensor, the position sensor is triggered when the driving device drives the cover body to move to the second position.
5. The sealing device according to claim 1, further comprising a heating device arranged on the cover body, the cover body is provided with a plurality of openings, the heating device is in a sheet structure, the heating device is provided with a plurality of first through holes, and the plurality of first through holes are arranged in one-to-one correspondence with the plurality of openings.
6. The sealing device according to claim 5, further comprising a heat preservation cover connected with the cover body, the heating device is arranged between the heat preservation cover and the cover body, the heat preservation cover is provided with a plurality of second through holes, and the plurality of second through holes are arranged in one-to-one correspondence with the plurality of first through holes.
7. The sealing device according to claim 5, further comprising a temperature sensor arranged on the cover body, the temperature sensor is located at an end of the cover body away from the driving device; a heat preservation layer is arranged on a bottom of the cover body and an outer portion of the reagent bin.
8. The sealing device according to claim 7, further comprising an over-temperature protector arranged on the cover body, the over-temperature protector is located at one side of the temperature sensor. The sealing device according to any one of claims 1-8; a reagent bin provided with a liquid taking opening, the sealing device being arranged on a top portion of the reagent bin; a guide rail, the cover body being slidably connected with the reagent bin through the guide rail. The reagent storage device according to claim 9. 9. A reagent storage device, characterized by, 10. A sample analyzer characterized by,