Anti-dandruff itching-relieving shampoo and preparation method thereof
By using a shampoo preparation method that combines amino acid surfactants, anti-dandruff agents, anti-itch agents, and conditioning agents, the problems of existing shampoos being short-lasting and highly irritating have been solved, achieving significant dandruff removal, long-lasting itch relief, and gentle effects.
Patent Information
- Application Number
- CN202511187811.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-08-25
- Publication Date
- 2025-11-14
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing anti-dandruff and anti-itch shampoos do not provide long-lasting effects, are highly irritating, and are difficult to effectively solve dandruff and itching problems.
Shampoo is prepared by using a compound of amino acid surfactants, anti-dandruff agents, antipruritic agents, moisturizers and conditioning agents, through a specific combination ratio and preparation process, including the preparation of aqueous phase solution, functional phase solution and low-temperature emulsification treatment.
It achieves significant dandruff removal and long-lasting itch relief, while being gentle and non-irritating to the scalp and hair, and exhibits good product stability.
Smart Images
Figure CN120938841A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of shampoo technology, and in particular to an anti-dandruff and anti-itch shampoo and its preparation method. Background Technology
[0002] With the fast pace of life and increased environmental pollution, scalp health problems are becoming increasingly prominent, with excessive dandruff and itchy scalp being common issues that plague many people. Dandruff is mainly related to the overgrowth of fungi such as Malassezia and abnormal scalp cell metabolism, while itchy scalp may be caused by fungal irritation, scalp dryness, or allergies.
[0003] There are many types of anti-dandruff and anti-itch shampoos on the market, but many products have problems such as short-lasting anti-dandruff and anti-itch effects, high scalp irritation, and dry hair. Therefore, the development of a highly effective, gentle, and long-lasting anti-dandruff and anti-itch shampoo is of great practical significance. Summary of the Invention
[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing an anti-dandruff and anti-itch shampoo and its preparation method.
[0005] To achieve the above objectives, the present invention adopts the following technical solution: an anti-dandruff and anti-itch shampoo, comprising the following components by weight: 10-20 parts amino acid surfactant, 5-10 parts anti-dandruff agent, 3-8 parts anti-itch agent, 5-10 parts moisturizer, 2-5 parts conditioning agent, 0.1-0.5 parts preservative, 0.1-0.5 parts fragrance, and the balance being deionized water.
[0006] As a further description of the above technical solution:
[0007] The amino acid surfactant is a compound of sodium lauroyl sarcosinate and cocamidopropyl betaine in a weight ratio of 2:1.
[0008] As a further description of the above technical solution:
[0009] The dandruff remover is a compound of zinc pyrithione and salicylic acid in a weight ratio of 3:2.
[0010] As a further description of the above technical solution:
[0011] The antipruritic agent is a compound of dipotassium glycyrrhizate and allantoin, with a weight ratio of 1:1.
[0012] As a further description of the above technical solution:
[0013] The moisturizer is a compound of glycerin and propylene glycol in a weight ratio of 3:2.
[0014] As a further description of the above technical solution:
[0015] The conditioning agent is a compound of polydimethylsiloxane and cationic guar gum in a weight ratio of 2:1.
[0016] As a further description of the above technical solution:
[0017] The preservative is sodium benzoate.
[0018] A method for preparing an anti-dandruff and anti-itch shampoo, the method comprising the following steps:
[0019] Preparation of aqueous solution: Add deionized water to the reaction vessel, start stirring, and heat to 60-70℃; add amino acid surfactant and humectant in sequence, and stir until completely dissolved to prepare aqueous solution;
[0020] Preparation of the functional phase solution: Add the anti-dandruff agent and antipruritic agent to deionized water, disperse them by ultrasonication at 30-50kHz for 5-10 minutes, and then slowly drop them into the aqueous phase solution. Maintain the temperature at 60-70℃ and stir at a stirring speed of 50-80r / min for 15-25 minutes to prepare the functional phase solution.
[0021] Low-temperature emulsification: Cool the active phase solution to 45°C, add the emulsified conditioning agent, preservative, and fragrance, turn on the high-shear emulsifier, and emulsify and shear at a speed of 2000-3000 r / min for 10-15 minutes to prepare the shampoo system.
[0022] Post-treatment: Filter the shampoo system using a 100-200 mesh filter to remove insoluble matter, impurities, or unevenly dispersed particles; transfer the filtered shampoo system to a vacuum degassing tank and degas it for 10-15 minutes at a vacuum of -0.05 to -0.08 MPa to remove air mixed in with the shampoo system.
[0023] Quality inspection and packaging: The degassed shampoo is subjected to quality inspection. After passing the inspection, it is filled and packaged according to the product specifications to obtain the finished anti-dandruff and anti-itch shampoo.
[0024] The present invention has the following beneficial effects:
[0025] This invention, through the rational selection of components such as amino acid surfactants, anti-dandruff agents, antipruritic agents, moisturizers, and conditioning agents, and the optimization of the proportions of each component, results in a shampoo with the following beneficial effects:
[0026] Significant dandruff-reducing effect: Zinc pyrithione can effectively inhibit the growth and reproduction of Malassezia, while salicylic acid can remove aging keratinocytes. When used together, the two work synergistically to reduce dandruff production from the root.
[0027] Long-lasting anti-itch effect: Dipotassium glycyrrhizate has anti-inflammatory and anti-allergic effects, while allantoin can soothe the scalp and reduce itching. When combined, the two can quickly relieve scalp itching symptoms and have a long-lasting effect.
[0028] Gentle and non-irritating: Utilizing a surfactant blend of sodium lauroyl sarcosinate and cocamidopropyl betaine, this formula produces rich, fine foam with moderate cleansing power and minimal irritation to the scalp and hair. Simultaneously, moisturizers and conditioning agents are added to effectively retain scalp and hair moisture, improve hair combability and shine, and prevent dryness and split ends. Attached Figure Description
[0029] Figure 1 This is a flowchart of the method of the present invention. Detailed Implementation
[0030] Example 1
[0031] Weigh the following components by weight: 8 parts sodium lauroyl sarcosinate, 4 parts cocamidopropyl betaine, 3 parts zinc pyrithione, 2 parts salicylic acid, 1.5 parts dipotassium glycyrrhizate, 1.5 parts allantoin, 3 parts glycerin, 2 parts propylene glycol, 1.33 parts polydimethylsiloxane, 0.67 parts cationic guar gum, 0.1 parts sodium benzoate, 0.1 parts fragrance, and 73.33 parts deionized water.
[0032] Preparation method:
[0033] Preparation of aqueous solution: Add deionized water to the reaction vessel, start stirring, and heat to 60°C; add sodium lauroyl sarcosinate, cocamidopropyl betaine, glycerol, and propylene glycol in sequence, and stir until completely dissolved to prepare an aqueous solution;
[0034] Preparation of the functional phase solution: Zinc pyrithione, salicylic acid, dipotassium glycyrrhizate, and allantoin were added to deionized water and dispersed by ultrasonication at 30 kHz for 8 minutes. The mixture was then slowly added dropwise to the aqueous phase solution. The solution was maintained at 60 ℃ and stirred at 60 r / min for 20 minutes to prepare the functional phase solution.
[0035] Low-temperature emulsification: Cool the active phase solution to 45°C, add emulsified polydimethylsiloxane, cationic guar gum, sodium benzoate, and fragrance, turn on the high-shear emulsifier, and emulsify and shear at 2000 r / min for 12 minutes to prepare the shampoo system.
[0036] Post-treatment: Filter the shampoo system using a 100-mesh filter to remove insoluble matter, impurities, or unevenly dispersed particles; transfer the filtered shampoo system to a vacuum degassing tank and degas it for 10 minutes at a vacuum of -0.05MPa to remove air mixed in with the shampoo system.
[0037] Quality inspection and packaging: The degassed shampoo is subjected to quality inspection. After passing the inspection, it is filled and packaged according to the product specifications to obtain the finished anti-dandruff and anti-itch shampoo.
[0038] Example 2
[0039] Weigh the following components by weight: 12 parts sodium lauroyl sarcosinate, 6 parts cocamidopropyl betaine, 6 parts zinc pyrithione, 4 parts salicylic acid, 4 parts dipotassium glycyrrhizate, 4 parts allantoin, 6 parts glycerin, 4 parts propylene glycol, 3.33 parts polydimethylsiloxane, 1.67 parts cationic guar gum, 0.5 parts sodium benzoate, 0.5 parts fragrance, and 43.5 parts deionized water.
[0040] Preparation method:
[0041] Preparation of aqueous solution: Add deionized water to the reaction vessel, start stirring, and heat to 65°C; add sodium lauroyl sarcosinate, cocamidopropyl betaine, glycerol, and propylene glycol in sequence, and stir until completely dissolved to prepare an aqueous solution;
[0042] Preparation of the efficacy phase solution: Zinc pyrithione, salicylic acid, dipotassium glycyrrhizate, and allantoin were added to deionized water and dispersed by ultrasonication at 40 kHz for 10 minutes. The solution was then slowly added dropwise to the aqueous phase solution. The solution was maintained at 65 ℃ and stirred at 70 r / min for 15 minutes to prepare the efficacy phase solution.
[0043] Low-temperature emulsification: Cool the active phase solution to 45°C, add emulsified polydimethylsiloxane, cationic guar gum, sodium benzoate, and fragrance, turn on the high-shear emulsifier, and emulsify and shear at a speed of 2500 r / min for 10 minutes to prepare the shampoo system.
[0044] Post-treatment: The shampoo system is filtered using a 120-mesh filter to remove insoluble matter, impurities, or unevenly dispersed particles; the filtered shampoo system is then transferred to a vacuum degassing tank and degassed for 12 minutes at a vacuum of -0.06 MPa to remove air mixed into the shampoo system.
[0045] Quality inspection and packaging: The degassed shampoo is subjected to quality inspection. After passing the inspection, it is filled and packaged according to the product specifications to obtain the finished anti-dandruff and anti-itch shampoo.
[0046] Example 3
[0047] Weigh the following components by weight: 10 parts sodium lauroyl sarcosinate, 5 parts cocamidopropyl betaine, 4.5 parts zinc pyrithione, 3 parts salicylic acid, 2.5 parts dipotassium glycyrrhizate, 2.5 parts allantoin, 4.5 parts glycerin, 3 parts propylene glycol, 2 parts polydimethylsiloxane, 1 part cationic guar gum, 0.3 parts sodium benzoate, 0.3 parts fragrance, and 56.9 parts deionized water.
[0048] Preparation method:
[0049] Preparation of aqueous solution: Add deionized water to the reaction vessel, start stirring, and heat to 70°C; add sodium lauroyl sarcosinate, cocamidopropyl betaine, glycerol, and propylene glycol in sequence, and stir until completely dissolved to prepare an aqueous solution;
[0050] Preparation of the efficacy phase solution: Zinc pyrithione, salicylic acid, dipotassium glycyrrhizate, and allantoin were added to deionized water and dispersed by ultrasonication at 45 kHz for 10 minutes. The solution was then slowly added dropwise to the aqueous phase solution. The solution was maintained at 70°C and stirred at 75 r / min for 25 minutes to prepare the efficacy phase solution.
[0051] Low-temperature emulsification: Cool the active phase solution to 45°C, add emulsified polydimethylsiloxane, cationic guar gum, sodium benzoate, and fragrance, turn on the high-shear emulsifier, and emulsify and shear at 3000 r / min for 12 minutes to prepare the shampoo system.
[0052] Post-treatment: The shampoo system is filtered using a 150-mesh filter to remove insoluble matter, impurities, or unevenly dispersed particles; the filtered shampoo system is then transferred to a vacuum degassing tank and degassed for 10 minutes at a vacuum of -0.08 MPa to remove air mixed into the shampoo system.
[0053] Quality inspection and packaging: The degassed shampoo is subjected to quality inspection. After passing the inspection, it is filled and packaged according to the product specifications to obtain the finished anti-dandruff and anti-itch shampoo.
[0054] Comparative Example 1
[0055] This comparative example provides a commercially available anti-dandruff and anti-itch shampoo as a control sample.
[0056] Dandruff removal effect test
[0057] Experimental subjects: Sixty volunteers with excessive dandruff were randomly divided into three groups of 20 each. Each group used the shampoo from Examples 1-3 and the shampoo from Comparative Example 1, respectively, once a day for seven consecutive days.
[0058] Test method: Before use and 7 days after use, dandruff samples were collected from volunteers' scalps. The weight of the dandruff was measured by weighing, and the dandruff reduction rate was calculated.
[0059] Dandruff reduction rate = (Dandruff weight before use - Dandruff weight after use) / Dandruff weight before use × 100%
[0060] Table 1. Experimental results of the dandruff removal test.
[0061]
[0062]
[0063] The experimental results show that the shampoos of Examples 1-3 of the present invention reduced dandruff by more than 85% after 7 days of use, which is significantly higher than that of the commercially available shampoo of Comparative Example 1, indicating that the shampoo of the present invention has a significant dandruff removal effect.
[0064] Anti-itch effect test
[0065] Experimental subjects: Sixty volunteers with scalp itching symptoms were randomly divided into three groups of 20 each. Each group used the shampoos of Examples 1-3 and Comparative Example 1, respectively. The time and duration of itching relief after use were recorded.
[0066] Testing method: Before use, volunteers assessed their itching level, classifying it as severe, moderate, or mild. After using the shampoo, volunteers were asked about changes in itching level every 5 minutes. The time it took for the itching to significantly decrease (from severe to moderate or from moderate to mild) and the duration of complete disappearance or reduced itching were recorded.
[0067] Table 2. Experimental results of the itch relief test.
[0068] Group Average time (minutes) for significant reduction in itching sensation Average time (in hours) for itching to subside Example 1 12 13 Example 2 10 14 Example 3 11 13.5 Comparative Example 1 20 8
[0069] Experimental results show that the shampoos of Examples 1-3 of the present invention can quickly relieve scalp itching symptoms. The average time for significant relief of itching is between 10 and 12 minutes, and the average time for sustained relief is between 13 and 14 hours. Both are superior to the commercially available shampoo of Comparative Example 1, indicating that the anti-itch effect of the shampoo of the present invention is long-lasting.
[0070] Stimulation test
[0071] Experimental subjects: Thirty healthy New Zealand white rabbits were randomly divided into three groups of 10 each. Skin irritation tests were conducted on the shampoos of Examples 1-3 and Comparative Example 1, respectively.
[0072] Test method: The rabbit skin irritation test method was used. An appropriate amount of shampoo was applied to the shaved area on the back of each rabbit once a day for 7 consecutive days. The skin was observed to see if there were any irritation reactions such as erythema or edema.
[0073] Table 3. Experimental results of the stimulation test
[0074] Group Incidence of erythema (%) Incidence of edema (%) Example 1 0 0 Example 2 0 0 Example 3 0 0 Comparative Example 1 10 5
[0075] The experimental results show that after 7 days of continuous use, the shampoos of Examples 1-3 of the present invention did not cause any irritation such as erythema or edema on the rabbits' skin. However, some rabbits with the commercially available shampoo of Comparative Example 1 showed mild erythema and edema. This indicates that the shampoo of the present invention is mild, non-irritating, and highly safe.
[0076] Stability test
[0077] Experimental method: The shampoos of Examples 1-3 were placed in transparent glass bottles and stored in a constant temperature chamber at 40℃ for 3 months. The products were observed to see if there were any phenomena such as layering, precipitation, or discoloration. Then, they were stored in a refrigerator at -10℃ for 3 months. After being taken out and restored to room temperature, the stability of the products was observed again.
[0078] Experimental results: After high-temperature and low-temperature storage, none of the shampoos in Examples 1-3 showed any phenomena such as layering, sedimentation, or discoloration, indicating good product stability.
[0079] In summary, the anti-dandruff and anti-itch shampoo provided by this invention has the advantages of significant anti-dandruff effect, long-lasting anti-itch effect, gentle and non-irritating properties, and good stability. Its preparation method is simple and feasible, and suitable for industrial production.
[0080] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A dandruff-reducing and anti-itch shampoo, characterized in that: By weight, it includes the following components: 10-20 parts amino acid surfactant, 5-10 parts anti-dandruff agent, 3-8 parts antipruritic agent, 5-10 parts moisturizer, 2-5 parts conditioning agent, 0.1-0.5 parts preservative, 0.1-0.5 parts fragrance, and the balance is deionized water.
2. The anti-dandruff and anti-itch shampoo according to claim 1, characterized in that: The amino acid surfactant is a compound of sodium lauroyl sarcosinate and cocamidopropyl betaine in a weight ratio of 2:
1.
3. The anti-dandruff and anti-itch shampoo according to claim 1, characterized in that: The dandruff remover is a compound of zinc pyrithione and salicylic acid in a weight ratio of 3:
2.
4. The anti-dandruff and anti-itch shampoo according to claim 1, characterized in that: The antipruritic agent is a compound of dipotassium glycyrrhizate and allantoin, with a weight ratio of 1:
1.
5. The anti-dandruff and anti-itch shampoo according to claim 1, characterized in that: The moisturizer is a compound of glycerin and propylene glycol in a weight ratio of 3:
2.
6. The anti-dandruff and anti-itch shampoo according to claim 1, characterized in that: The conditioning agent is a compound of polydimethylsiloxane and cationic guar gum in a weight ratio of 2:
1.
7. The anti-dandruff and anti-itch shampoo according to claim 1, characterized in that: The preservative is sodium benzoate.
8. A method for preparing an anti-dandruff and anti-itch shampoo, characterized in that: This method for manufacturing the anti-dandruff and anti-itch shampoo according to any one of claims 1-7 includes the following steps: Preparation of aqueous solution: Add deionized water to the reaction vessel, start stirring, and heat to 60-70℃; add amino acid surfactant and humectant in sequence, and stir until completely dissolved to prepare aqueous solution; Preparation of the functional phase solution: Add the anti-dandruff agent and antipruritic agent to deionized water, disperse them by ultrasonication at 30-50kHz for 5-10 minutes, and then slowly drop them into the aqueous phase solution. Maintain the temperature at 60-70℃ and stir at a stirring speed of 50-80r / min for 15-25 minutes to prepare the functional phase solution. Low-temperature emulsification: Cool the active phase solution to 45°C, add the emulsified conditioning agent, preservative, and fragrance, turn on the high-shear emulsifier, and emulsify and shear at a speed of 2000-3000 r / min for 10-15 minutes to prepare the shampoo system. Post-treatment: Filter the shampoo system using a 100-200 mesh filter to remove insoluble matter, impurities, or unevenly dispersed particles; transfer the filtered shampoo system to a vacuum degassing tank and degas it for 10-15 minutes at a vacuum of -0.05 to -0.08 MPa to remove air mixed in with the system. Quality inspection and packaging: The degassed shampoo is subjected to quality inspection. After passing the inspection, it is filled and packaged according to the product specifications to obtain the finished anti-dandruff and anti-itch shampoo.