Multidrug-resistant escherichia coli bacteriophage and application thereof
By using Escherichia coli phage vB_EOP_Se004, the treatment challenge of multidrug-resistant Escherichia coli has been solved, achieving efficient and safe bacterial killing and protection of microecological balance, and it has the potential for self-replication and combination therapy.
CN120966767BActive Publication Date: 2026-07-03SHANXI PROVINCE CHINESE MEDICINE RESEARCH INSTITUTE
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- SHANXI PROVINCE CHINESE MEDICINE RESEARCH INSTITUTE
- Filing Date
- 2025-07-18
- Publication Date
- 2026-07-03
Smart Images
Figure CN120966767B_ABST
Abstract
This invention relates to the field of biomedical technology, and particularly to a multidrug-resistant Escherichia coli bacteriophage and its applications. This invention has screened an Escherichia coli bacteriophage, vB_EOP_Se004, which exhibits good killing effects against clinically isolated multidrug-resistant Escherichia coli. It also demonstrates strong tolerance to temperature and pH, maintaining stable survival rates within a pH range of 4-10 and a temperature range of -20°C to 70°C. This bacteriophage can effectively address the resistance of multidrug-resistant Escherichia coli to multiple antibiotics, offering significant advantages in the clinical treatment of infections.
Need to check novelty before this filing date? Find Prior Art