Traditional Chinese medicine formula for treating blood vessel clogging

Abstract

A traditional Chinese medicine formula for treating blood vessel clogging belongs to the field of traditional Chinese medicine formulas, and comprises the following main raw materials: 29-31 parts of black pearl, 11-13 parts of codonopsis pilosula, 7-9 parts of saffron crocus, 8-10 parts of angelica sinensis, 190-210 parts of leek, 9-11 parts of pseudo-ginseng, 37-43 parts of hawthorn, 95-105 parts of astragalus membranaceus, 18-22 parts of kudzu vine root, 8-10 parts of peach kernel, 8-10 parts of prepared rehmannia root, 9-11 parts of radix rehmanniae, 11-13 parts of white paeony root, 3 parts of red ginseng, 9-11 parts of radix ophiopogonis, 14-16 parts of spina date seed, 11-13 parts of Chinese yam, 14-15 parts of schisandra chinensis, 9-11 parts of polygonum multiflorum, 7-9 parts of cinnamon, 18-21 , 13-15 parts of anise and 12-14 parts of rhizoma polygonati. The traditional Chinese medicine composition has an obvious improvement effect on coronary artery insufficiency, myocardial ischemia, mitral valve, tricuspid valve, aortic valve regurgitation, chronic heart failure, patients needing operation bypass stenting, angina pectoris, myocardial infarction sequelae, cerebral ischemia, cerebrovascular sequelae and other symptoms caused by cardiac insufficiency, the dosage is small, the effect is fast, the cure rate is high, relapse is not prone to occurring, and the traditional Chinese medicine composition is suitable for clinical application. The effects of tonifying qi and activating blood, dredging channels and relieving pain, eliminating phlegm and removing blood stasis, tonifying heart and soothing nerves and the like can be achieved.

Description

Technical Field

[0001] This invention belongs to the field of traditional Chinese medicine formulas, specifically relating to a traditional Chinese medicine formula for treating vascular blockage. Background Technology

[0002] The heart is the power source that drives the circulation of blood in the human body. Through rhythmic contraction and relaxation, it propels blood to flow rapidly throughout the body, thereby ensuring the normal functioning of various life activities. Arteries and veins in the human body are the main channels for blood circulation. Under the power of the heart, blood circulates continuously in these blood vessels, providing the body with necessary nutrients and maintaining metabolism. The heart and blood vessels together form the core of the human circulatory system, responsible for providing essential nutrients to all vital organs. However, when the heart and blood vessels develop certain diseases, it can lead to a variety of uncomfortable symptoms, causing problems such as blood vessel blockage and insufficient blood supply. For example, coronary artery insufficiency due to coronary heart disease, myocardial ischemia, mitral, tricuspid, and aortic regurgitation, chronic heart failure, patients requiring bypass surgery and stenting, angina pectoris, sequelae of myocardial infarction, cerebral ischemia caused by heart failure, and sequelae of cerebrovascular disease all seriously affect the health of patients. Various causes of poor blood flow or blockage can also cause palpitations, anxiety, chest tightness, shortness of breath, insomnia, forgetfulness, irritability, and fatigue, which seriously trouble patients. Simply suppressing these symptoms with Western medicine can also have corresponding side effects. Summary of the Invention

[0003] To overcome the shortcomings of existing technologies, this invention provides a traditional Chinese medicine formula for treating vascular blockage and its production method, which can solve the above-mentioned technical problems.

[0004] The technical solution adopted by this invention to solve its technical problem is as follows: A traditional Chinese medicine formula (by weight) for treating vascular congestion is designed, the main ingredients of which include 29-31 parts black pearl, 11-13 parts Codonopsis pilosula, 7-9 parts saffron, 8-10 parts Angelica sinensis, 190-210 parts leek, 9-11 parts Panax notoginseng, 37-43 parts hawthorn, 95-105 parts Astragalus membranaceus, 18-22 parts Pueraria lobata, 8-10 parts peach kernel, 8-10 parts prepared Rehmannia glutinosa, 9-11 parts raw Rehmannia glutinosa, 11-13 parts white peony root, 3 parts red ginseng, 9-11 parts Ophiopogon japonicus, 14-16 parts jujube seed, 11-13 parts yam, 14-15 parts Schisandra chinensis, 9-11 parts Polygonum multiflorum, 7-9 parts cinnamon, and 18-21 parts Cuscuta chinensis. Job's tears 18-21 parts, star anise 13-15 parts, Polygonatum 12-14 parts.

[0005] Furthermore, the Chinese herbal formula is made into an oral liquid. After cleaning each component, the Chinese herbal medicine is decocted. Then, water four times the total amount of each component is added and simmered over medium heat for four hours. After simmering, it is placed in a constant temperature fermentation chamber for 48 hours and filtered to obtain the oral liquid. The fermentation temperature is controlled at 35 degrees Celsius.

[0006] Furthermore, the traditional Chinese medicine formula for treating vascular blockage (by weight parts) is as follows: Black pearl 30 parts, Codonopsis pilosula 12 parts, saffron 8 parts, Angelica sinensis 9 parts, leek 200 parts, Panax notoginseng 10 parts, hawthorn 40 parts, Astragalus membranaceus 100 parts, kudzu root 20 parts, peach kernel 9 parts, prepared Rehmannia glutinosa 9 parts, raw Rehmannia glutinosa 10 parts, white peony root 12 parts, red ginseng 3 parts, Ophiopogon japonicus 10 parts, jujube seed 15 parts, yam 12 parts, Schisandra chinensis 15 parts, Polygonum multiflorum 10 parts, cinnamon 8 parts, Cuscuta chinensis 20 parts, Coix seed 20 parts, star anise 14 parts, Polygonatum sibiricum 13 parts.

[0007] Furthermore, the traditional Chinese medicine formula for treating vascular blockage (by weight parts) is as follows: Black pearl 29 parts, Codonopsis pilosula 12 parts, Saffron 9 parts, Angelica sinensis 10 parts, Leek 190 parts, Panax notoginseng 11 parts, Hawthorn 40 parts, Astragalus membranaceus 98 parts, Kudzu root 19 parts, Peach kernel 10 parts, Rehmannia glutinosa (processed) 9 parts, Rehmannia glutinosa (raw) 11 parts, White peony root 11 parts, Red ginseng 3 parts, Ophiopogon japonicus 9 parts, Ziziphus jujuba seed 15 parts, Dioscorea opposita 11 parts, Schisandra chinensis 14 parts, Polygonum multiflorum 11 parts, Cinnamon 9 parts, Cuscuta chinensis 20 parts, Coix seed 20 parts, Star anise 13 parts, Polygonatum sibiricum 13 parts Furthermore, the traditional Chinese medicine formula for treating vascular blockage (by weight) is as follows: weigh out 31 parts of black pearl, 11 parts of Codonopsis pilosula, 8 parts of saffron, 8 parts of Angelica sinensis, 210 parts of leek, 9 parts of Panax notoginseng, 37 parts of hawthorn, 105 parts of Astragalus membranaceus, 21 parts of kudzu root, 10 parts of peach kernel, 9 parts of prepared Rehmannia glutinosa, 10 parts of raw Rehmannia glutinosa, 12 parts of white peony root, 3 parts of red ginseng, 10 parts of Ophiopogon japonicus, 15 parts of jujube seed, 12 parts of yam, 15 parts of Schisandra chinensis, 10 parts of Polygonum multiflorum, 8 parts of cinnamon, 19 parts of Cuscuta chinensis, 20 parts of coix seed, 15 parts of star anise, and 13 parts of Polygonatum sibiricum.

[0008] The beneficial effects of this invention are as follows: The traditional Chinese medicine formula for treating vascular blockage provided by this invention has a significant effect on improving symptoms such as insufficient coronary artery blood supply, myocardial ischemia, mitral, tricuspid, and aortic regurgitation, chronic heart failure, patients requiring bypass surgery and stenting, angina pectoris, sequelae of myocardial infarction, cerebral ischemia caused by heart failure, and sequelae of cerebrovascular diseases. It has the advantages of small dosage, rapid effect, significant curative effect, high cure rate and low recurrence rate. It can also invigorate qi and blood circulation, clear the meridians and relieve pain, eliminate phlegm and remove blood stasis, and nourish the heart and calm the mind. Detailed Implementation

[0009] A traditional Chinese medicine formula for treating vascular blockage includes the following components in parts by weight: The ingredients are: 29-31 parts black pearl, 11-13 parts codonopsis, 7-9 parts saffron, 8-10 parts angelica, 190-210 parts leek, 9-11 parts notoginseng, 37-43 parts hawthorn, 95-105 parts astragalus, 18-22 parts kudzu root, 8-10 parts peach kernel, 8-10 parts prepared rehmannia root, 9-11 parts raw rehmannia root, 11-13 parts white peony root, 3 parts red ginseng, 9-11 parts ophiopogon root, 14-16 parts jujube seed, 11-13 parts yam, 14-15 parts schisandra fruit, 9-11 parts polygonum multiflorum, 7-9 parts cinnamon, 18-21 parts dodder seed, 18-21 parts coix seed, 13-15 parts star anise, and 12-14 parts polygonatum rhizome. The black pearl is weighed in powder form.

[0010] The preferred dosage form of the traditional Chinese medicine formula for treating vascular blockage described in this invention is an oral liquid. After cleaning, the traditional Chinese medicine is decocted, and then water is added at four times the total amount of each component. The decoction is simmered over medium heat for four hours. After simmering (temperature controlled at 35 degrees Celsius), it is placed in a constant temperature fermentation chamber for 48 hours and then filtered to obtain the oral liquid.

[0011] The traditional Chinese medicine formula for treating vascular blockage described in this invention is mainly used to improve symptoms such as coronary artery insufficiency, myocardial ischemia, mitral, tricuspid, and aortic regurgitation, chronic heart failure, patients requiring bypass surgery and stenting, angina pectoris, sequelae of myocardial infarction, cerebral ischemia caused by heart failure, and sequelae of cerebrovascular diseases.

[0012] The present invention provides a detailed description of the technical solutions provided by the present invention in conjunction with the following embodiments, but these should not be construed as limiting the scope of protection of the present invention.

[0013] Example 1 Weigh out 30 parts of black pearl, 12 parts of Codonopsis pilosula, 8 parts of saffron, 9 parts of Angelica sinensis, 200 parts of leek, 10 parts of Panax notoginseng, 40 parts of hawthorn, 100 parts of Astragalus membranaceus, 20 parts of kudzu root, 9 parts of peach kernel, 9 parts of prepared Rehmannia glutinosa, 10 parts of raw Rehmannia glutinosa, 12 parts of white peony root, 3 parts of red ginseng, 10 parts of Ophiopogon japonicus, 15 parts of jujube seed, 12 parts of yam, 15 parts of Schisandra chinensis, 10 parts of Polygonum multiflorum, 8 parts of cinnamon, 20 parts of Cuscuta chinensis, 20 parts of Coix lacryma-jobi, 14 parts of star anise, and 13 parts of Polygonatum sibiricum. After washing, decoct the herbs, then add four times the total amount of water of each component and simmer over medium heat for four hours. After simmering (temperature controlled at 35 degrees Celsius), place in a constant temperature fermentation chamber for 48 hours and filter to obtain an oral liquid.

[0014] Example 2 Weigh out 29 parts of black pearl, 12 parts of Codonopsis pilosula, 9 parts of saffron, 10 parts of Angelica sinensis, 190 parts of leek, 11 parts of Panax notoginseng, 40 parts of hawthorn, 98 parts of Astragalus membranaceus, 19 parts of kudzu root, 10 parts of peach kernel, 9 parts of prepared Rehmannia glutinosa, 11 parts of raw Rehmannia glutinosa, 11 parts of white peony root, 3 parts of red ginseng, 9 parts of Ophiopogon japonicus, 15 parts of jujube seed, 11 parts of yam, 14 parts of Schisandra chinensis, 11 parts of Polygonum multiflorum, 9 parts of cinnamon, 20 parts of Cuscuta chinensis, 20 parts of Coix lacryma-jobi, 13 parts of star anise, and 13 parts of Polygonatum sibiricum. After washing, decoct the herbs, then add four times the total amount of water of each component and simmer over medium heat for four hours. After simmering (temperature controlled at 35 degrees Celsius), place in a constant temperature fermentation chamber for 48 hours and filter to obtain oral liquid.

[0015] Example 3 Weigh out 31 parts of black pearl, 11 parts of Codonopsis pilosula, 8 parts of saffron, 8 parts of Angelica sinensis, 210 parts of leek, 9 parts of Panax notoginseng, 37 parts of hawthorn, 105 parts of Astragalus membranaceus, 21 parts of kudzu root, 10 parts of peach kernel, 9 parts of prepared Rehmannia glutinosa, 10 parts of raw Rehmannia glutinosa, 12 parts of white peony root, 3 parts of red ginseng, 10 parts of Ophiopogon japonicus, 15 parts of jujube seed, 12 parts of yam, 15 parts of Schisandra chinensis, 10 parts of Polygonum multiflorum, 8 parts of cinnamon, 19 parts of Cuscuta chinensis, 20 parts of coix seed, 15 parts of star anise, and 13 parts of Polygonatum sibiricum. After washing, decoct the herbs, then add four times the total amount of water of each component and simmer over medium heat for four hours. After simmering (temperature controlled at 35 degrees Celsius), place in a constant temperature fermentation chamber for 48 hours and filter to obtain oral liquid.

[0016] Patients with symptoms such as coronary artery insufficiency, myocardial ischemia, mitral, tricuspid, and aortic regurgitation, chronic heart failure, requiring bypass surgery and stenting, angina pectoris, sequelae of myocardial infarction, cerebral ischemia due to heart failure, and sequelae of cerebrovascular diseases were collected. The oral liquid obtained using the formula in Example 1 was used in clinical trials, achieving good results with no toxic side effects. Two case studies are described below: Case 1: Ms. Si, 52 years old, underwent a cardiac ultrasound examination on March 6, 2019. The ultrasound findings included left ventricular enlargement and thickening, a 5mm deep hypoechoic area in the right ventricular cavity, mild aortic regurgitation, mild pulmonary hypertension, mild tricuspid regurgitation, slightly rapid flow velocity across the aortic valve, and reduced left ventricular diastolic function (grade 1). She took the oral solution described in Example 1 3-6 times daily, 20-30ml each time, for a two-month course of treatment. Her clinical symptoms improved significantly after the first course of treatment, and disappeared after the third course. On October 8, 2019, a cardiac ultrasound examination showed normal right ventricular diameter, normal ventricular wall thickness and motion, normal valve morphology, and normal aortic and pulmonary artery diameters. After consolidation treatment, no abnormal blood flow signals were observed.

[0017] Case 2, Gao XX, male, 38 years old, underwent a cardiac ultrasound examination on January 8, 2019. The ultrasound diagnosis showed that the ascending aorta was widened, the aortic valve had mild regurgitation, and the left ventricular diastolic function was reduced. He took the oral liquid in Example 1 3 to 6 times a day, with each dose being 20 to 30 ml. One course of treatment lasted two months. The clinical symptoms improved significantly after the first course of treatment, and the symptoms disappeared after the third course of treatment. When the cardiac ultrasound was repeated, no abnormalities were found in the intracardiac structure.

[0018] In summary, after applying the traditional Chinese medicine formula for treating vascular blockage described in this invention, the clinical symptoms disappeared after the first course of treatment. Two more courses of treatment were then administered to complete the recovery of cardiac function, meaning the three courses essentially achieved the therapeutic goal. There were no toxic side effects, and the formula had the effects of invigorating qi and blood circulation, clearing the meridians and relieving pain, eliminating phlegm and removing blood stasis, and nourishing the heart and calming the mind. It was effective for symptoms such as coronary artery insufficiency, myocardial ischemia, mitral, tricuspid, and aortic regurgitation, chronic heart failure, patients requiring bypass surgery, angina pectoris, sequelae of myocardial infarction, cerebral ischemia caused by heart failure, and sequelae of cerebrovascular diseases. Furthermore, it significantly improved symptoms such as palpitations, chest tightness, shortness of breath, insomnia, forgetfulness, irritability, and fatigue in some patients.

[0019] The oral liquid prepared from the traditional Chinese medicine formula for treating vascular blockage should be used with caution by patients who have undergone coronary artery bypass grafting. Spicy and cold foods should be avoided, and penicillin and cephalosporin antibiotics should not be used while taking this product.

[0020] Finally, it should be noted that the above embodiments are only used to illustrate and not limit the technical solutions of the present invention. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that modifications or equivalent substitutions can still be made to the present invention without departing from the spirit and scope of the present invention. Any modifications or partial substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A traditional Chinese medicine formula for treating vascular blockage, characterized in that, The main raw materials (by mass) include: Black pearl 29-31 parts, Codonopsis pilosula 11-13 parts, Saffron 7-9 parts, Angelica sinensis 8-10 parts, Leek 190-210 parts, Panax notoginseng 9-11 parts, Hawthorn 37-43 parts, Astragalus membranaceus 95-105 parts, Pueraria lobata 18-22 parts, Peach kernel 8-10 parts, Rehmannia glutinosa (processed) 8-10 parts, Rehmannia glutinosa (raw) 9-11 parts, White peony root 11-13 parts, Red ginseng 3 parts, Ophiopogon japonicus 9-11 parts, Ziziphus jujuba var. spinosa 14-16 parts, Dioscorea opposita 11-13 parts, Schisandra chinensis 14-15 parts, Polygonum multiflorum 9-11 parts, Cinnamomum cassia 7-9 parts, Cuscuta chinensis 18-21 parts, Coix lacryma-jobi 18-21 parts, Illicium verum 13-15 parts, Polygonatum sibiricum 12-14 parts.

2. The traditional Chinese medicine formula for treating vascular blockage according to claim 1, characterized in that: The traditional Chinese medicine formula is made into an oral liquid. After cleaning each component, the traditional Chinese medicine is decocted. Then, water is added at four times the total amount of each component and simmered over medium heat for four hours. After simmering, it is placed in a constant temperature fermentation chamber for 48 hours and filtered to obtain the oral liquid. The fermentation temperature is controlled at 35 degrees Celsius.

3. The traditional Chinese medicine formula for treating vascular blockage according to claim 1, characterized in that, The herbal formula (by mass fraction) includes: 30 parts black pearl, 12 parts codonopsis, 8 parts saffron, 9 parts angelica, 200 parts leek, 10 parts notoginseng, 40 parts hawthorn, 100 parts astragalus, 20 parts kudzu root, 9 parts peach kernel, 9 parts prepared rehmannia root, 10 parts raw rehmannia root, 12 parts white peony root, 3 parts red ginseng, 10 parts ophiopogon root, 15 parts jujube seed, 12 parts yam, 15 parts schisandra fruit, 10 parts he shou wu, 8 parts cinnamon, 20 parts dodder seed, 20 parts coix seed, 14 parts star anise, and 13 parts polygonatum rhizome.

4. The traditional Chinese medicine formula for treating vascular blockage according to claim 1, characterized in that, The herbal formula (by mass fraction) includes: 29 parts black pearl, 12 parts codonopsis, 9 parts saffron, 10 parts angelica, 190 parts leek, 11 parts notoginseng, 40 parts hawthorn, 98 parts astragalus, 19 parts kudzu root, 10 parts peach kernel, 9 parts prepared rehmannia root, 11 parts raw rehmannia root, 11 parts white peony root, 3 parts red ginseng, 9 parts ophiopogon root, 15 parts jujube seed, 11 parts yam, 14 parts schisandra fruit, 11 parts he shou wu, 9 parts cinnamon, 20 parts dodder seed, 20 parts coix seed, 13 parts star anise, and 13 parts polygonatum rhizome.

5. The traditional Chinese medicine formula for treating vascular blockage according to claim 1, characterized in that, The herbal formula (by mass fraction) includes: 31 parts black pearl, 11 parts codonopsis, 8 parts saffron, 8 parts angelica, 210 parts leek, 9 parts notoginseng, 37 parts hawthorn, 105 parts astragalus, 21 parts kudzu root, 10 parts peach kernel, 9 parts prepared rehmannia root, 10 parts raw rehmannia root, 12 parts white peony root, 3 parts red ginseng, 10 parts ophiopogon root, 15 parts jujube seed, 12 parts yam, 15 parts schisandra fruit, 10 parts he shou wu, 8 parts cinnamon, 19 parts dodder seed, 20 parts coix seed, 15 parts star anise, and 13 parts polygonatum.