Preparation method of liver-resolving decoction granules retaining volatile active ingredients
By using steam distillation and cyclodextrin inclusion technology, the problem of volatile loss of paeonol in Huaganjian granules was solved, thus achieving the stability and efficacy of Huaganjian granules and meeting the needs of modern life.
CN121570543APending Publication Date: 2026-02-27SICHUAN LVYE BAO GUANG PHARMA IND
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Patent Information
- Application Number
- CN202511731735.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-11-24
- Publication Date
- 2026-02-27
AI Technical Summary
Technical Problem
Traditional decoctions for liver health have problems such as being inconvenient to carry, unstable storage, and easy loss of the active ingredient paeonol due to volatility. Existing granule preparation methods have not effectively solved the problem of volatile loss of paeonol.
Method used
Paeonol was extracted by steam distillation and then encapsulated with cyclodextrin. Combined with full-formula extraction and concentration granulation, a stable paeonol β-cyclodextrin inclusion complex was formed, ensuring the stability of paeonol during preparation and storage.
Benefits of technology
It significantly improved the content and stability of paeonol, achieving controllable quality, portability, and efficacy of Huaganjian granules, meeting the needs of modern dosage forms.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention provides a preparation method of liver-removing decoction granules capable of retaining volatile effective components. The preparation method comprises the following steps: S1, independently extracting and stabilizing paeonol; s2, a step of carrying out whole-formula extraction; s3, a step of performing concentration; s4, a step of carrying out granulation; s5, carrying out particle finishing; and S6, carrying out subpackaging. The invention aims to overcome the defects in the prior art and provides the preparation method of the liver-removing decoction granules. According to the method, the volatile component paeonol in the moutan bark is independently extracted and stabilized before being decocted through an innovative'shunt treatment 'process, so that the effective component is reserved in the granules to the maximum extent, and the stable product quality and the remarkable curative effect are ensured. Meanwhile, the liver-removing decoction granules prepared by the method provided by the invention have the advantages of high paeonol content, stable quality and convenience in taking and storage.
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